Best TWAS P=1.7e-07 · Best GWAS P=3.67e-08 conditioned to 0.00367
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD244 | 0.07 | 0.08 | lasso | 3 | 0.08 | 1.1e-09 | -5.0 | -5.1 | 3.0e-07 | 0.98 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CD244 | 0.05 | 0.05 | lasso | 2 | 0.05 | 3.2e-06 | -5.1 | -5.2 | 2.4e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | CD244 | 0.03 | 0.00 | blup | 59 | 0.02 | 5.7e-04 | -5.0 | -5.2 | 2.0e-07 | 0.91 | 0.02 | 0.94 | FALSE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | ITLN1 | 0.13 | 0.13 | lasso | 1 | 0.13 | 2.2e-04 | -5.2 | 5.2 | 1.7e-07 | -0.61 | 0.03 | 0.78 | TRUE |