[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr19:388,413-1,802,433

Best TWAS P=5.1e-16 · Best GWAS P=9.1e-21 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Breast Mammary Tissue	POLR2E	0.39	0.06	lasso	8	0.16	2.1e-08	5.6	-8.1	5.1e-16	-0.47	0.41	0.17	TRUE
9	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	GPX4	0.17	0.03	blup	45	0.10	1.2e-05	5.4	6.4	1.5e-10	0.67	0.01	0.92	TRUE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GPX4	0.06	0.02	enet	8	0.06	5.8e-07	8.9	5.8	8.6e-09	0.63	0.01	0.98	TRUE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPX4	0.12	0.11	lasso	4	0.12	3.9e-13	5.4	5.7	1.1e-08	0.63	1.00	0.00	TRUE
3	GTEx	Cells Transformed fibroblasts	GPX4	0.37	0.20	lasso	9	0.23	4.3e-17	5.4	5.6	2.3e-08	0.63	1.00	0.00	TRUE
12	The Cancer Genome Atlas	Testicular Germ Cell Tumors	GPX4	0.27	0.03	lasso	5	0.15	4.5e-06	1.9	5.6	2.5e-08	0.47	0.01	0.35	TRUE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	POLR2E	0.06	0.00	blup	53	0.03	2.3e-04	-1.3	-5.2	1.5e-07	-0.37	0.05	0.26	TRUE
1	CommonMind	Brain Pre-frontal Cortex	POLR2E	0.23	0.14	bslmm	451	0.17	5.2e-20	-5.1	-5.2	1.9e-07	-0.12	1.00	0.00	TRUE
5	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	GPX4	0.08	0.01	lasso	7	0.02	4.7e-03	9.3	8.1	5.3e-16	0.87	0.00	0.97	FALSE
4	GTEx	Prostate	GPX4	0.41	0.23	lasso	3	0.22	4.1e-06	5.4	6.9	7.2e-12	0.65	0.02	0.80	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ABCA7	0.05	0.02	blup	71	0.04	4.7e-05	-5.1	-5.5	5.0e-08	-0.29	0.44	0.04	FALSE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPX4	0.21	0.15	lasso	4	0.14	6.9e-15	5.4	5.4	5.8e-08	0.66	1.00	0.00	FALSE