TWAS hub - ABCA7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.4550	0.1430	7.4e-03	0.021	NA	0.060	NA	0.058	9.6e-02	NA	1.2e-02	NA	1.4e-02
2	GTEx	Brain Cerebellum	0.4560	0.1410	5.7e-03	0.229	NA	0.128	NA	0.189	2.2e-07	NA	1.3e-04	NA	3.0e-06
3	GTEx	Breast Mammary Tissue	0.1990	0.0640	1.3e-03	0.043	NA	0.042	NA	0.083	2.9e-03	NA	3.3e-03	NA	4.6e-05
4	GTEx	Lung	0.1493	0.0489	1.1e-03	0.064	NA	0.075	NA	0.084	1.3e-05	NA	2.1e-06	NA	5.9e-07
5	GTEx	Nerve Tibial	0.2025	0.0604	7.4e-04	0.056	NA	0.019	NA	0.053	8.2e-05	NA	1.5e-02	NA	1.3e-04
6	GTEx	Skin Sun Exposed Lower leg	0.2980	0.0560	2.5e-06	0.143	NA	0.232	NA	0.202	7.4e-12	NA	4.1e-19	NA	1.3e-16
7	GTEx	Spleen	0.3830	0.1180	3.0e-03	0.156	NA	0.068	NA	0.165	8.4e-05	NA	8.2e-03	NA	5.0e-05
8	GTEx	Whole Blood	0.3340	0.0440	1.8e-13	0.252	NA	0.206	NA	0.219	4.2e-23	NA	9.5e-19	NA	5.4e-20
9	YFS	Blood	0.1980	0.0295	0.0e+00	0.037	0.100	0.135	0.141	0.089	4.3e-12	7.6e-31	5.6e-42	6.3e-44	1.1e-27
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0515	0.0200	3.1e-04	0.025	0.037	0.032	NA	0.033	7.2e-04	4.7e-05	1.5e-04	NA	1.1e-04
11	TCGA	Lung Adenocarcinoma	0.0565	0.0195	6.3e-06	0.028	0.036	0.026	NA	0.021	2.9e-04	3.9e-05	4.9e-04	NA	1.5e-03
12	TCGA	Prostate Adenocarcinoma	0.0904	0.0311	3.7e-05	0.029	0.028	0.027	NA	0.029	5.1e-04	5.8e-04	6.8e-04	NA	4.5e-04
13	TCGA	Thyroid Carcinoma	0.0950	0.0340	2.6e-04	0.060	0.028	0.016	NA	0.052	1.7e-06	8.7e-04	9.2e-03	NA	8.1e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Blood White Count	6.4	47.6	92.0	-7.9	-7.3	-6.1	-4.2	-7.2	-8.4	-4.0	-4.0	-5.0	-9.6	-6.5	-8.7	-7.7
Alzheimer’s Disease (including proxy)	6.0	8.8	19.2	2.0	2.2	-1.3	3.6	4.0	1.7	2.6	2.6	2.1	3.9	1.8	4.4	3.9
Wheeze or whistling in the chest in last year	4.7	8.4	20.0	2.8	2.6	2.2	2.4	2.8	3.5	2.5	2.2	0.9	4.5	3.3	3.5	2.9
Crohns Disease (2017)	3.9	8.6	29.7	0.4	-1.4	0.5	-2.9	-1.8	-0.6	-2.1	-2.6	-2.2	-5.5	-4.8	-4.4	-3.0
Alzheimer’s Disease (in father)	3.8	4.2	16.8	-0.7	0.5	-0.3	4.1	0.9	-0.2	3.1	3.1	3.7	0.5	1.0	1.1	-0.3
Unable to work because of sickness or disability	3.8	4.9	11.8	0.7	3.3	0.3	1.5	3.4	1.6	1.4	1.4	0.8	2.5	1.8	3.4	3.1
Irritable Bowel Disease (IBD)	3.5	8.4	31.6	-0.6	-1.4	-0.5	-2.5	-1.9	-0.5	-1.1	-1.4	-1.2	-5.6	-5.0	-4.5	-4.0
Lupus	3.2	4.9	11.2	0.7	1.3	0.7	2.1	1.1	1.6	2.0	2.5	3.0	3.3	3.1	2.7	2.5
Worry too long after embarrassment	3.0	5.0	10.4	3.0	2.1	0.4	-1.1	2.5	3.2	-2.7	-3.1	-2.5	1.4	-0.1	2.2	2.0
Hayfever, allergic rhinitis or eczema	2.9	6.3	15.1	-1.4	-1.7	-0.4	-3.2	-2.5	-0.2	-3.9	-3.9	-3.3	-2.6	-2.6	-2.4	-1.1
Length of working week for main job	2.4	2.7	9.0	-2.0	-1.2	-0.7	-0.8	-1.4	-2.2	-0.9	-0.1	-0.4	-1.9	-1.8	-2.0	-3.0
Tinnitus: Yes, now most or all of the time	2.4	2.8	8.7	-0.0	1.0	-1.0	-2.9	0.4	0.0	-2.3	-2.1	-0.4	-2.0	-3.0	-0.7	-1.4
Chronotype (morning person)	2.3	5.4	10.8	-2.4	-2.6	-2.1	-2.7	-3.3	-2.2	-1.6	-1.7	-1.3	-2.8	-1.9	-2.8	-2.1
Hypothyroidism (self reported)	2.2	5.0	11.8	0.3	1.4	1.4	2.4	2.4	1.7	2.0	1.4	2.5	2.0	3.3	3.4	2.9
Sensitivity / hurt feelings	2.2	3.7	10.0	3.2	2.4	1.9	-0.5	2.4	2.8	-0.1	-0.1	-0.8	1.8	0.1	2.2	2.6
Allergy	2.2	5.0	14.5	-0.1	0.1	-0.2	3.4	0.8	-1.3	3.8	3.5	3.6	1.9	2.4	1.5	0.5
Lung cancer (father)	2.2	2.5	9.5	-3.1	-1.0	-0.6	1.6	-1.4	-1.1	2.3	2.6	1.2	-0.3	1.4	-0.5	-0.8
Medication: Allopurinol	2.2	2.9	12.5	1.6	0.5	0.2	-2.5	0.1	-0.1	-3.5	-2.8	-1.5	-0.7	-2.4	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.8	14.1	-2.1	-1.4	-1.1	-2.8	-1.7	-1.9	-3.8	-3.3	-2.5	-1.3	-1.7	-1.6	-1.3
Current tobacco smoking	2.0	3.2	7.5	0.4	1.1	0.2	2.7	1.2	0.4	2.4	2.2	1.2	2.4	2.7	1.7	2.0
Lung FVC	1.9	9.6	27.2	-2.1	-2.1	1.1	-3.8	-2.4	-1.7	-5.2	-4.1	-2.6	-3.2	-4.2	-3.2	-1.9
Alzheimer’s Disease (in mother)	1.8	2.1	6.1	1.7	1.9	-0.6	1.2	2.5	1.1	1.1	1.1	0.7	1.9	0.7	1.8	1.1
Emphysema/chronic bronchitis	1.8	2.1	5.7	2.3	2.2	0.9	-0.8	2.4	2.3	-0.8	-0.3	-0.6	0.4	-1.0	0.8	1.2
Financial situation satisfaction	1.8	2.2	9.1	1.6	1.2	1.1	-2.1	0.6	0.4	-2.8	-3.0	-0.3	-0.1	-0.7	0.9	0.7
Heart disease (siblings)	1.8	2.2	5.8	0.5	0.1	1.2	-2.4	-0.4	-0.5	-1.9	-1.1	-2.3	-1.3	-2.4	-1.5	-0.9
Pain all over the body in last month	1.7	1.8	7.1	-1.2	-0.7	-1.0	1.1	-0.8	-1.5	1.0	0.5	-0.7	1.3	2.2	1.3	2.7
Leg pain on walking	1.7	2.1	3.9	-1.2	-0.5	-1.2	-1.6	-1.2	-1.4	-2.0	-1.7	-2.0	-1.3	-1.3	-1.2	-1.7
Mineral and other dietary supplements	1.7	2.3	5.6	1.1	0.2	0.8	2.4	0.1	0.7	2.2	1.9	2.1	1.9	2.3	0.7	0.5
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	8.0	-1.5	-2.6	-0.9	-0.9	-2.8	-1.4	-0.3	-0.2	0.1	-0.2	0.8	-1.2	-1.4
Allergy or Eczema	1.5	3.9	7.1	-0.9	-0.9	-0.3	-2.2	-1.8	0.0	-2.7	-2.6	-2.6	-2.5	-2.6	-2.1	-1.8
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	4.8	1.6	1.0	-0.5	0.0	1.5	0.6	0.0	-0.0	0.2	2.2	1.2	2.1	2.2
Nervous feelings	1.5	2.8	6.1	1.5	1.3	1.4	-2.3	0.6	2.0	-2.3	-2.4	-2.5	-1.3	-1.5	-0.3	0.3
Hayfever/allergic rhinitis (self-reported)	1.5	1.9	6.0	-0.8	-0.7	-0.1	-2.5	-0.7	-1.0	-1.2	-1.2	-1.6	-2.1	-2.2	-1.3	-0.1
Neuroticism score	1.5	3.1	6.9	1.9	1.3	1.4	-2.0	1.3	2.3	-2.2	-2.6	-2.3	0.4	-0.7	1.4	1.4
Average weekly beer plus cider intake	1.5	2.2	9.5	0.3	-1.0	-0.6	0.4	-0.8	-0.9	0.6	0.1	0.7	3.0	3.1	1.7	1.6
Frequency of depressed mood in last 2 weeks	1.4	2.0	6.6	0.3	1.5	1.5	1.2	1.6	1.1	0.9	0.8	1.0	1.6	0.7	2.1	2.6
Maternal smoking around birth	1.4	2.1	5.4	0.1	1.2	1.1	1.7	1.5	1.4	1.0	1.3	0.7	2.3	1.8	1.9	1.2
Chronic bronchitis/emphysema (father)	1.4	1.6	5.0	-1.2	2.2	-0.4	0.5	1.6	0.6	1.2	1.2	1.1	1.1	1.4	1.8	0.6
Gout (self-reported)	1.4	1.9	4.8	0.7	0.6	-0.3	-1.5	0.0	-0.7	-2.2	-1.5	-0.7	-1.8	-2.0	-1.4	-2.1
Average weekly spirits intake	1.3	1.6	4.9	0.9	1.9	-1.6	-0.4	2.2	1.1	-0.0	0.3	0.2	-1.3	-1.4	-1.2	-1.7
Average weekly fortified wine intake	1.3	1.5	4.5	-2.1	-0.9	-2.1	1.6	0.1	-1.5	1.2	1.3	0.2	-0.3	0.8	-0.9	-1.0
Serious illness, injury or assault to yourself	1.3	1.6	6.9	-0.2	1.0	0.3	0.5	0.8	0.3	1.1	1.3	1.4	1.9	0.9	1.4	2.6
Supplements: Glucosamine	1.3	1.8	8.3	0.5	-0.1	-1.1	-1.9	-0.3	-0.6	-2.0	-1.3	-2.9	-0.9	-1.4	-0.6	-0.3
Birth weight of first child	1.3	2.4	9.2	3.0	-0.1	-0.2	-0.6	0.1	0.4	-0.6	-0.8	-2.2	2.3	1.3	1.6	2.6
Number of full sisters	1.3	1.6	5.3	-0.8	-0.5	-1.7	1.1	-1.0	-0.9	1.9	2.0	2.3	-0.1	0.7	0.0	-1.0
Eye problems/disorders: None of the above	1.2	1.3	3.7	-0.7	-1.9	0.1	-1.0	-1.1	-0.8	0.5	0.8	-0.4	-1.9	-1.5	-1.6	-1.1
Migraine (self-reported)	1.2	1.5	2.6	1.3	1.6	0.1	1.6	0.9	1.3	1.4	1.3	1.5	1.4	1.6	0.5	0.5
Illnesses of father: Heart disease	1.2	1.7	4.2	1.7	1.3	0.8	-1.4	1.7	2.0	-0.8	-1.0	-0.8	1.1	0.1	1.1	1.7
Illnesses of siblings: Diabetes	1.2	1.5	3.2	1.0	0.7	1.7	-1.8	0.5	0.3	-1.4	-1.5	-1.3	-1.6	-1.5	-0.6	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	4.3	0.0	-0.7	-1.3	-2.0	-0.8	-0.8	-1.1	-0.7	-0.5	-0.9	-2.1	-1.7	-0.6
Blood Platelet Count	1.1	13.0	36.1	-2.2	-2.6	0.5	-4.2	-2.8	-2.0	-3.9	-3.0	-6.0	-2.9	-4.6	-4.8	-3.8
Respiratory disease	1.1	2.4	5.8	2.4	2.0	2.2	0.2	1.5	2.3	-0.5	-0.1	-1.6	1.5	0.7	1.0	1.5
Worrier / anxious feelings	1.1	2.0	5.8	2.1	2.4	0.8	-0.9	1.9	1.9	-1.2	-1.5	-1.5	0.3	-0.3	1.1	0.4
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	2.6	1.0	1.6	1.3	1.6	1.6	1.4	1.3	1.0	1.0	1.6	0.7	1.5	1.0
Number of live births	1.1	1.5	4.9	1.7	0.3	-1.1	-1.2	-0.1	-0.1	-1.3	-1.9	-0.5	0.9	0.1	1.6	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.7	10.7	-1.1	-1.4	1.7	-2.6	-1.5	-1.2	-3.3	-2.5	-1.5	-1.8	-2.1	-1.8	-1.1
Loud music exposure frequency	1.1	1.2	5.5	0.4	2.3	-0.5	0.7	2.2	1.7	0.4	0.3	0.4	0.5	-0.3	0.8	0.7
Chronic bronchitis/emphysema (mother)	1.1	1.3	3.7	1.9	0.8	-0.5	-1.0	1.1	0.1	-1.2	-1.1	-1.8	0.3	-0.4	1.0	1.5
Forced vital capacity (FVC), Best measure	1.1	4.2	13.5	-0.8	-0.8	2.0	-2.9	-1.1	-0.9	-3.7	-2.5	-1.3	-2.0	-2.8	-1.9	-1.0
Medication for cholesterol	1.1	1.7	6.2	-0.7	-0.1	0.3	-0.8	-0.5	-0.0	-1.6	-2.0	-2.5	-1.6	-1.5	-1.3	-0.9
Smoking status: Current	1.1	1.8	4.4	0.4	0.8	0.2	2.1	0.9	0.1	1.8	1.6	0.8	1.6	2.0	1.2	1.5
Ever taken oral contraceptive pill	1.1	1.2	3.2	0.2	1.1	0.3	1.3	1.5	1.8	0.9	0.7	0.6	0.9	0.9	1.7	1.0
Medication: Lisinopril	1.1	1.4	3.2	1.8	1.4	-0.9	0.1	1.6	0.9	-1.1	-1.0	-1.1	1.3	0.3	1.6	1.0
Irritability	1.1	1.9	5.8	-1.3	0.2	0.6	-1.7	0.3	0.8	-2.1	-2.4	-2.2	-0.3	-0.3	1.1	1.5
Basal cell carcinoma (self-reported)	1.1	1.4	3.8	-0.3	0.1	-1.2	-1.0	-0.5	-1.2	-0.9	-0.8	0.6	-1.9	-2.0	-0.9	-1.9
Ulcerative Colitis (UC)	1.0	1.9	6.6	-0.3	-0.2	-0.8	-0.6	-0.6	0.5	0.4	0.3	0.3	-2.5	-2.6	-1.9	-2.4
Prostate Cancer	1.0	1.3	4.5	0.1	0.9	-0.4	0.6	1.1	0.6	-0.0	-0.5	-0.1	1.6	1.7	2.1	2.0
Blood Eosinophil Count	1.0	7.3	28.7	0.7	-0.7	1.1	-0.9	-1.2	-0.1	-1.4	0.0	-5.1	-1.1	-2.5	-5.2	-5.4
Angina	1.0	1.3	2.8	0.8	1.3	0.8	0.9	1.4	1.2	0.9	0.9	0.8	1.7	1.1	1.5	0.6
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	9.1	-0.8	-1.4	1.9	-2.4	-1.5	-1.0	-3.0	-2.3	-1.2	-1.4	-2.2	-1.8	-1.1
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	6.8	0.7	1.2	1.5	0.6	1.8	1.0	0.4	0.0	1.1	1.0	1.8	2.6	2.2
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.7	1.3	0.6	0.0	-1.4	0.3	-0.0	-1.9	-1.5	-1.3	0.9	-0.5	0.8	1.0
Handedness (chirality/laterality): Left-handed	1.0	1.2	1.8	1.0	1.1	-1.0	1.3	1.4	0.8	1.3	1.2	1.3	0.8	0.6	1.1	1.3
Miserableness	1.0	1.7	5.5	0.4	0.1	1.4	-1.8	0.4	1.1	-1.8	-2.4	-1.6	0.8	0.1	0.5	1.6
Illnesses of father: High blood pressure	1.0	1.2	3.5	-0.5	-1.9	-0.7	-1.3	-1.8	-0.9	0.0	0.1	-0.1	-1.2	-1.1	-1.4	-1.1
Fractured/broken bones in last 5 years	1.0	1.3	5.1	1.3	0.8	-0.8	1.3	0.7	-0.3	1.8	2.3	1.7	-0.3	0.2	-0.1	-0.0
Neuroticism (Nagel 2018)	0.9	2.1	5.4	1.4	1.2	0.7	-1.8	1.0	2.1	-1.7	-2.0	-2.3	-0.3	-1.0	0.7	1.0
Neuroticism	0.9	2.1	6.7	1.6	1.1	0.6	-1.1	1.1	2.1	-1.5	-1.8	-2.6	0.5	-0.3	1.5	1.3
Relative age of first facial hair	0.9	1.9	6.6	-0.5	-0.2	-0.7	-1.5	-0.3	-0.3	-1.6	-1.5	-1.3	-1.9	-2.6	-1.6	-1.3
Diabetes (father)	0.9	1.2	4.7	-0.6	-0.7	2.2	1.1	-0.4	-0.0	0.7	0.6	2.1	-0.2	1.3	0.5	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	9.1	-3.0	-1.7	-1.9	-1.1	-1.8	-2.0	-0.5	-0.9	0.2	-0.9	-0.4	-0.6	-0.8
Stomach or abdominal pain in last month	0.9	1.1	2.4	1.6	1.6	-0.6	1.3	1.0	0.8	1.3	1.4	1.3	0.2	0.0	0.2	-0.6
Medication: Atenolol	0.9	1.2	4.8	0.1	-0.4	-0.7	0.8	0.4	0.4	1.9	2.2	0.5	1.4	0.9	1.3	0.9
High blood pressure (mother)	0.9	1.2	4.5	-2.1	-1.1	-0.3	-1.0	-0.9	-1.0	-1.2	-0.9	-0.8	-1.2	-0.5	-1.0	-1.4
Medication: Ramipril	0.9	1.2	3.5	-1.1	-1.9	-1.5	0.0	-1.4	-1.1	0.9	0.7	-0.0	0.6	1.8	-0.2	0.4
Medication: Simvastatin	0.9	1.4	4.5	-0.5	-0.4	0.3	1.0	-0.2	-0.4	1.9	2.1	1.3	1.3	2.0	0.7	0.4
Tense / ‘highly strung’	0.9	1.6	4.2	0.5	0.1	0.2	-1.4	-0.4	1.5	-2.0	-1.6	-0.9	-2.0	-1.8	-0.7	0.1
Blood clot in the leg (DVT)	0.9	1.2	2.7	1.6	1.4	1.3	-1.2	1.0	1.4	-1.2	-0.9	-0.6	-0.8	-0.9	-0.2	-0.5
Medication: Ventolin 100micrograms inhaler	0.9	1.2	5.7	2.4	1.6	0.1	0.1	1.0	1.9	0.4	0.9	0.4	-0.1	-0.9	0.2	0.3
Heart disease (mother)	0.9	1.1	5.8	-1.4	-1.0	-2.4	-0.5	-1.2	-1.0	-0.3	-0.6	-0.0	-1.2	0.4	-0.6	-0.3
Suffer from ‘nerves’	0.9	1.4	3.6	0.3	-0.0	0.2	-1.2	-0.5	0.2	-1.2	-1.9	-1.0	-1.7	-1.5	-1.3	-1.9
Had major operations	0.9	1.1	3.2	-0.2	-0.0	0.2	-0.6	-0.3	-1.2	-1.4	-1.8	0.6	-1.4	-1.6	-0.8	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.9	-0.6	-0.4	-0.5	-1.7	-0.8	-0.3	-1.6	-0.8	-1.6	-1.1	-1.2	-0.7	-0.2
Long-standing illness, disability or infirmity	0.9	1.3	3.8	0.1	1.2	-0.6	1.4	1.3	0.9	1.3	1.5	0.7	1.1	1.9	1.0	0.9
Eye problems/disorders: Cataract	0.9	1.1	4.0	1.6	0.2	-2.0	0.1	-0.5	-0.9	-1.5	-2.0	-0.1	0.4	0.4	0.1	0.2
Osteoporosis (self-reported)	0.9	1.1	2.3	0.6	-0.5	-0.4	-1.5	-1.3	-0.8	-1.5	-0.9	-0.3	-1.1	-1.3	-1.4	-0.7
Alcohol drinker status: Never	0.9	1.0	3.6	0.8	1.9	1.1	0.5	1.4	1.6	1.0	1.1	0.4	0.5	0.4	0.5	-0.3
Cholesterol lowering medication	0.9	1.4	3.2	-0.3	-0.2	-0.5	1.5	0.2	-0.3	1.3	1.8	0.8	1.5	1.7	1.6	1.4
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.3	1.5	1.3	1.3	-1.2	0.9	1.3	-1.1	-0.9	-0.5	-1.1	-1.1	-0.5	-0.5
Alcohol drinker status: Previous	0.9	1.0	4.0	1.5	0.7	-0.2	-0.7	0.7	1.2	-0.1	-0.3	-0.4	1.3	-0.2	1.3	2.0
Medication: Metformin	0.8	1.2	2.5	1.6	0.8	0.6	1.4	0.7	0.5	1.3	1.5	0.6	1.4	1.2	1.1	0.1
Relative age voice broke	0.8	1.2	5.4	-0.6	-0.9	-0.3	-1.3	-0.9	-1.2	-0.4	0.1	-0.7	-1.3	-2.3	-1.4	-0.9
Forced vital capacity (FVC)	0.8	3.2	10.8	-0.7	-0.6	2.2	-2.4	-0.9	-0.7	-3.3	-2.4	-1.0	-1.5	-2.5	-1.5	-0.8
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	4.2	0.2	1.1	1.1	-2.0	0.5	0.1	-1.5	-1.3	-0.6	-0.2	-1.2	0.7	0.3
Falls in the last year	0.8	1.1	6.8	2.6	1.2	0.6	-0.5	1.4	1.3	-0.2	0.0	-0.4	-0.1	-1.1	0.6	-0.7
Qualifications: A levels/AS levels or equivalent	0.8	1.7	8.7	2.9	0.3	-0.4	-0.5	1.5	0.4	-1.6	-1.7	-1.2	0.8	-0.9	0.4	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	4.9	-0.5	0.9	2.2	0.5	0.3	0.0	0.1	0.2	0.7	-0.3	0.7	-0.7	-1.9
Asthma	0.8	1.6	5.5	1.3	1.9	1.3	-0.0	1.4	2.4	-0.0	0.3	-1.8	1.2	0.3	0.8	0.9
Exposure to tobacco smoke at home	0.8	0.9	3.1	0.6	-0.2	-1.3	0.9	-0.7	-0.5	1.6	1.8	1.4	0.1	0.1	0.0	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.5	-0.2	1.0	2.1	-1.0	0.4	0.2	-1.4	-1.9	-0.8	0.7	0.7	1.1	1.1
Number of children fathered	0.8	0.9	2.1	0.7	1.1	0.1	0.8	0.4	0.4	1.1	1.1	1.4	1.2	1.5	0.7	0.6
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.6	1.0	-1.0	-1.1	-1.8	-0.5	0.6	-0.5	-0.8	-1.9	-0.3	-1.0	-0.2	-0.1
Mood swings	0.8	1.5	5.5	0.3	-0.4	0.1	-2.4	-0.3	0.2	-1.9	-1.9	-1.4	-0.1	-1.1	0.5	1.9
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	4.2	-1.3	0.1	1.1	-0.3	0.1	0.0	-0.2	0.2	-1.1	-1.5	-1.6	-1.7	-2.0
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.2	-0.9	-0.3	-0.8	-1.8	-0.2	-0.2	-1.0	-0.8	-1.2	-1.5	-1.4	-0.9	-0.8
Number of operations (self-reported)	0.8	1.1	8.3	2.9	1.1	0.0	0.9	1.4	1.1	0.5	0.3	0.6	0.3	0.0	0.8	0.4
Worry (Nagel 2018)	0.7	1.5	3.8	1.1	1.4	-0.2	-1.2	0.6	1.5	-1.6	-1.9	-1.7	-1.1	-1.1	-0.2	-0.4
Breast Cancer	0.7	1.8	4.8	1.4	1.3	1.0	-0.5	1.6	2.2	-1.8	-1.4	-2.0	0.6	0.2	0.9	0.9
Primary Biliary Cirrhosis	0.7	1.0	3.1	1.2	0.0	0.8	1.8	0.9	0.0	1.4	1.6	1.1	1.0	0.7	0.3	0.1
Hand grip strength (left)	0.7	1.8	6.3	-0.5	0.7	2.0	-2.5	0.0	1.0	-2.1	-1.5	-1.6	-0.7	-1.4	-0.2	-0.1
Hearing difficulty/problems: Yes	0.7	1.1	5.0	0.3	0.1	2.0	-2.2	-0.2	0.5	-1.4	-1.1	-0.7	-0.2	-0.7	0.2	0.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.1	-0.1	1.4	0.0	1.4	1.5	0.7	0.6	0.3	0.8	0.2	0.9	0.8	1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.9	1.0	0.5	1.2	1.2	0.9	0.8	1.7	1.4	0.4	-0.0	0.7	0.2	-0.1
Ever had hysterectomy (womb removed)	0.7	0.8	2.4	-1.6	-0.5	0.6	0.9	-0.3	-0.4	0.0	-0.3	-0.8	0.7	1.4	0.9	1.5
Diabetes (mother)	0.7	1.0	2.2	-0.2	-0.8	-0.3	0.2	-1.2	-1.5	1.0	1.5	0.9	-0.4	-0.3	-1.3	-1.5
Age when periods started (menarche)	0.7	1.6	5.0	0.1	0.9	1.0	2.1	0.8	0.9	2.2	2.0	1.6	0.4	1.2	0.8	0.0
Multivitamins +/- minerals	0.7	0.9	2.8	0.1	0.6	1.2	-1.7	0.4	0.5	-1.0	-1.3	-1.4	-0.2	-0.9	0.6	0.6
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	3.1	-0.7	-0.9	-1.8	-1.0	-0.8	-1.0	-0.7	-0.5	-0.9	-0.7	-0.9	-0.9	-0.9
Mouth/teeth dental problems	0.7	1.1	3.2	-0.3	-1.3	-1.7	-0.2	-1.2	-1.8	-0.6	-0.9	0.4	-0.6	-0.3	0.1	1.6
Heart attack	0.7	0.9	2.1	0.8	0.7	0.5	1.2	1.1	0.9	1.4	1.2	1.0	1.0	0.8	0.8	0.2
Fluid intelligence score	0.7	1.4	5.4	2.3	1.0	0.8	0.8	1.8	1.6	-0.4	-0.7	-0.5	0.8	0.3	1.2	1.1
Pulse rate	0.7	1.1	2.2	-1.5	0.2	-0.1	-1.4	-0.6	-1.1	-0.7	-1.5	-1.4	-1.2	-0.3	-1.1	-0.9
Impedance of arm (left)	0.7	3.1	8.6	2.0	2.0	2.4	-1.1	2.7	2.9	-0.9	-1.5	-0.0	0.8	-1.3	1.5	1.3
Hair/balding pattern: Pattern 4	0.7	1.8	6.1	-1.7	-0.9	-0.1	-1.3	-1.4	-1.5	-2.5	-2.5	-0.8	-0.8	-0.7	-0.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	4.2	2.1	-0.3	-0.1	-0.9	0.6	0.1	-1.7	-2.0	-0.5	0.8	-0.2	0.3	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	2.8	1.6	-0.9	-0.4	0.4	-0.4	0.4	0.2	0.2	-1.4	1.2	1.7	-0.1	0.9
Pulse wave peak to peak time	0.7	0.8	2.7	1.4	0.8	0.5	0.6	1.4	1.7	-0.3	-0.5	0.6	0.6	-0.0	1.1	0.5
Shortness of breath walking on level ground	0.7	0.8	3.3	0.4	1.8	0.3	0.6	1.6	1.0	0.7	0.7	-0.1	1.2	0.8	0.4	0.1
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.9	0.8	-0.2	1.7	-0.1	-0.4	-0.3	-1.1	-1.0	-1.1	1.2	1.1	0.6	0.7
Angina (self-reported)	0.7	0.9	2.1	0.5	1.0	0.5	1.0	1.1	0.8	0.9	0.9	1.0	1.4	1.1	1.3	0.6
Overall health rating	0.7	1.4	4.0	1.4	2.0	0.4	0.9	1.9	1.8	1.4	1.2	0.4	0.6	0.7	0.3	0.3
Family relationship satisfaction	0.7	0.8	4.0	2.0	1.1	0.0	0.0	0.8	0.4	-1.0	-1.0	-0.6	1.1	0.2	0.8	0.7
Loneliness, isolation	0.7	1.0	2.5	1.6	1.4	0.3	0.5	1.3	1.1	1.3	1.2	0.1	0.8	0.5	1.1	0.7
Average weekly champagne plus white wine intake	0.7	0.9	3.9	-1.0	-1.1	-2.0	0.4	-1.0	-1.6	0.2	-0.1	0.3	-0.7	-0.5	-0.7	-0.9
Medication: Bendroflumethiazide	0.7	1.1	3.3	1.8	0.5	-0.9	0.3	0.6	0.3	1.3	1.7	0.8	1.2	1.4	0.5	0.5
Commuting to job workplace: Cycle	0.7	0.8	5.8	-2.4	0.2	-0.7	1.2	0.3	-0.1	0.5	0.8	1.3	-0.3	-0.0	-0.3	-0.3
Heart attack/myocardial infarction (self-reported)	0.7	0.8	2.2	0.7	0.6	0.4	1.3	1.0	0.8	1.5	1.3	1.0	0.8	0.8	0.6	0.1
Depressed Affect (Nagel 2018)	0.6	1.2	2.7	0.6	0.9	1.1	-1.6	0.9	1.6	-0.8	-1.1	-1.6	0.2	-0.6	1.0	1.4
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.9	1.1	1.2	0.7	0.8	1.6	1.5	0.0	-0.2	0.4	1.6	1.0	2.0	1.5
Blood Red Count	0.6	5.5	16.2	1.0	-0.9	2.1	-2.5	-1.4	-0.8	-0.8	-0.4	-1.3	-4.0	-3.6	-3.8	-3.2
Waist Hip Ratio (WHR)	0.6	2.9	8.2	-1.1	-1.1	-1.0	-2.1	-1.4	-0.6	-2.0	-2.9	-2.6	-1.8	-1.0	-0.9	-1.9
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.4	-1.1	-0.2	-0.2	0.4	-1.0	-0.5	0.0	0.1	-1.2	-1.1	-0.1	-1.1	-1.5
Medication for hormone replacement therapy	0.6	0.7	2.5	1.6	0.4	1.5	0.1	0.4	0.9	0.3	0.3	0.9	0.8	0.1	0.6	0.8
Vitamin and mineral supplements	0.6	0.8	2.2	-0.7	-0.9	-1.5	1.3	-1.0	-0.8	0.6	0.5	0.7	0.4	1.2	-0.3	-0.6
Medication: Levothyroxine sodium	0.6	1.0	3.5	0.5	0.8	1.4	-0.3	1.3	0.4	-0.7	-0.9	0.7	0.5	0.6	1.9	1.2
Hair/balding pattern: Pattern 2	0.6	0.8	3.9	1.5	-0.3	-2.0	-0.5	-0.2	0.0	0.8	0.7	0.5	-0.4	-0.6	-0.5	-1.1
Impedance of arm (right)	0.6	2.9	8.8	1.8	2.1	2.5	-0.9	2.7	3.0	-0.6	-1.0	0.3	0.9	-1.2	1.5	1.1
Happiness	0.6	0.8	2.5	1.6	1.0	1.1	-0.7	0.6	0.8	-1.2	-1.4	-0.0	-0.1	-0.2	0.5	0.5
Depression (self-reported)	0.6	0.7	1.7	0.6	1.1	1.3	0.9	1.0	-0.1	1.0	1.2	0.8	-0.1	-0.1	-0.4	-0.9
Prospective memory result	0.6	0.8	2.1	-0.1	-0.5	-0.6	-0.2	-1.4	-1.2	0.8	0.5	0.7	-0.5	1.4	-0.8	-1.4
Birth weight	0.6	1.3	4.5	0.3	-1.4	-1.1	-1.1	-1.1	-0.5	-1.6	-1.8	-2.1	-0.0	-0.7	0.2	0.7
Ever had bowel cancer screening	0.6	0.7	2.2	-1.1	-0.7	-1.2	1.2	-0.7	-0.3	0.5	0.4	0.4	0.5	1.5	-0.6	-0.6
Diabetes diagnosed by doctor	0.6	0.9	2.4	0.6	0.8	-0.5	1.4	0.8	0.1	1.3	1.3	0.0	1.2	1.5	0.9	0.5
Asthma (self-reported)	0.6	1.3	4.2	1.2	1.6	1.3	0.0	1.3	2.1	0.2	0.5	-1.6	1.0	0.3	0.6	0.7
Osteoarthritis (self-reported)	0.6	0.7	3.4	-0.4	-0.8	-1.8	0.1	-0.8	-1.8	-0.1	0.6	0.1	-0.7	-0.3	-0.7	-0.2
Hearing aid user	0.6	0.7	1.8	-1.0	0.7	0.0	1.1	0.5	0.3	1.2	1.3	-0.1	1.1	0.8	0.7	-0.1
Medication: Blood pressure	0.6	1.1	3.7	0.4	-1.6	-1.9	-0.3	-1.1	-1.3	1.0	1.4	0.8	0.5	0.9	-0.3	0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.1	0.2	-0.7	0.7	-1.4	-0.8	-0.7	-0.5	0.2	-0.9	-0.8	-1.3	-1.4	-1.0
High cholesterol (Self-reported)	0.6	1.0	2.1	-1.1	-0.1	-1.0	0.4	-0.2	-0.9	1.2	1.3	1.0	1.0	1.2	1.4	1.1
Risk taking	0.6	0.9	2.3	-1.3	-1.2	-0.5	0.6	-1.5	-1.1	0.4	1.1	0.2	-0.9	0.1	-1.2	-0.2
Ever depressed for a whole week	0.6	0.8	2.0	0.6	0.4	0.5	-1.4	-0.1	-0.4	-1.2	-1.2	-0.8	-1.4	-1.1	-0.3	-0.3
Ovarian Cancer	0.5	0.6	1.9	-0.0	1.1	1.4	0.4	0.5	0.8	-0.6	-0.5	-1.2	-0.8	-0.6	-0.3	-0.8
Smoking Status	0.5	1.1	4.3	0.3	-0.0	0.9	1.6	0.3	0.8	2.1	1.8	1.2	0.2	1.0	0.0	0.4
Medication: Co-codamol	0.5	0.6	2.6	-0.7	1.6	0.2	0.3	1.4	0.2	-0.1	-0.2	0.2	0.7	0.8	0.9	0.4
Severe depression (siblings)	0.5	0.5	1.4	-0.1	1.2	1.0	-0.2	1.2	0.7	-0.2	0.1	-0.8	0.9	-0.3	1.0	0.4
Pack years adult smoking proportion	0.5	0.7	3.3	0.6	0.4	-1.0	1.1	0.4	-0.8	1.3	1.8	0.6	0.6	-0.0	-0.1	-0.7
Taking other prescription medications	0.5	0.7	2.9	1.7	1.2	0.3	-0.1	1.2	0.6	-0.3	-0.2	-0.1	0.6	0.6	1.2	1.1
Alcohol usually taken with meals	0.5	0.9	2.4	-1.1	-0.5	-0.9	0.9	-0.4	-0.3	0.2	1.1	1.0	-1.0	-0.8	-1.3	-1.5
Hearing difficulty/problems with background noise	0.5	0.7	2.3	1.5	-0.6	1.4	-0.5	0.4	1.5	-0.1	0.4	0.2	0.6	0.3	0.7	1.2
Had other major operations	0.5	0.6	2.0	1.4	0.7	-0.6	-0.0	0.6	0.5	-1.0	-0.8	-1.4	0.3	-0.2	0.1	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.3	7.0	-2.6	-1.3	-1.0	-0.5	-1.7	-1.2	0.1	-0.4	0.5	-1.0	0.0	-0.6	-0.7
Qualifications: None of the above	0.5	1.1	3.0	-1.0	1.7	-0.2	1.3	1.2	-0.3	1.7	1.6	-0.7	0.4	0.2	0.6	-0.0
Illnesses of siblings	0.5	0.7	3.0	-0.7	-0.5	-1.2	0.8	-0.5	0.2	0.0	-0.5	0.5	1.4	0.8	0.6	1.7
Alcohol intake versus 10 years previously	0.5	0.8	2.0	-0.0	0.0	1.4	-0.7	0.4	0.4	-0.5	-0.3	-1.3	-1.2	-1.1	-0.9	-1.2
Medication: Cholesterol lowering	0.5	0.7	2.2	-0.8	-1.0	-0.8	0.2	-0.8	-1.0	1.3	1.0	0.5	0.8	1.5	0.2	-0.0
Pulse wave Arterial Stiffness index	0.5	0.6	2.3	-1.3	-0.7	-0.5	-0.4	-1.1	-1.5	0.4	0.5	-0.6	-0.5	0.1	-0.9	-0.3
Breastfed as a baby	0.5	0.6	3.6	1.0	-0.4	-1.9	-0.1	-0.3	-0.4	0.2	0.2	0.6	0.3	0.5	0.2	-1.3
Peak expiratory flow (PEF)	0.5	1.1	3.4	0.7	-0.6	0.7	-1.3	-1.0	-0.8	-1.8	-1.6	-1.3	-0.5	-1.0	-0.8	-0.3
Leg fat percentage (right)	0.5	1.7	5.6	-1.7	-1.9	-1.0	-0.9	-1.9	-2.4	0.9	0.8	-1.0	-0.6	-0.7	-1.2	-0.6
Age at first live birth	0.5	0.9	5.1	1.2	0.1	0.6	1.1	0.4	-0.0	-0.0	-0.0	-0.0	-1.0	-0.8	-1.0	-2.3
Health satisfaction	0.5	0.7	2.5	0.6	1.2	0.6	-0.4	0.9	0.6	0.4	0.0	0.2	-1.2	-1.0	-0.5	-1.6
Comparative height size at age 10	0.5	2.8	9.0	2.3	0.9	3.0	0.5	2.2	1.9	0.4	0.5	1.4	0.6	0.3	2.1	2.5
Supplements: Vitamin C	0.5	0.6	2.4	-0.8	0.0	0.2	1.1	0.1	0.2	-0.1	0.5	1.3	-1.5	-0.5	-1.0	-0.9
Qualifications: nursing, teaching	0.5	0.8	2.8	1.2	0.6	-1.2	0.6	0.6	0.6	-0.0	0.6	-0.2	1.7	0.8	0.8	1.3
Illnesses of father: None of the above (group 1)	0.5	0.6	1.1	-0.3	-1.0	0.2	-0.1	-0.8	-0.9	-0.7	-0.7	-1.0	-0.4	-0.8	-0.9	-0.9
Diastolic blood pressure, automated reading	0.5	1.5	9.3	0.4	-0.3	0.7	-1.9	-0.9	-0.3	-1.3	-1.5	-3.0	-0.6	-0.4	-0.9	0.7
Supplements: Calcium	0.5	0.5	1.5	0.2	-0.7	0.1	-1.0	-0.6	-0.5	-1.0	-1.2	-0.3	-1.0	-0.8	-0.6	0.4
Pack years of smoking	0.5	0.8	3.2	0.6	0.4	-1.1	1.0	0.4	-0.7	1.3	1.8	0.5	0.5	-0.1	-0.2	-1.0
Age at First Birth	0.4	0.6	2.8	1.7	1.7	0.6	-0.1	1.2	0.8	-0.0	-0.3	-0.1	0.2	-0.4	0.1	-0.0
Heel T-Score	0.4	3.0	7.0	-2.4	1.1	-1.8	0.1	1.8	1.0	0.7	0.2	2.6	1.6	2.6	2.4	1.0
Lung FEV1/FVC ratio	0.4	2.3	7.7	-1.4	-2.8	-1.5	1.5	-2.2	-1.8	1.1	0.9	0.9	-0.3	2.0	-0.8	-0.3
Hand grip strength (right)	0.4	1.2	6.1	-0.5	0.0	0.8	-2.5	-0.1	0.4	-1.6	-1.2	-1.3	-0.3	-1.2	0.1	0.8
Fed-up feelings	0.4	0.7	3.1	-0.4	0.5	1.8	-0.9	0.6	1.2	-0.3	-0.8	-0.2	0.5	0.1	1.1	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.6	-0.8	0.3	-0.1	-0.6	0.3	0.8	-1.0	-1.2	-1.1	0.3	-0.3	0.5	1.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.6	0.4	1.0	0.3	0.3	0.4	0.9	-0.2	-0.0	0.0	1.2	0.9	0.8	-0.4
Had menopause	0.4	0.5	2.9	1.7	0.7	-0.5	-0.6	0.2	1.1	-0.1	0.2	-0.4	-0.8	-0.2	0.6	0.0
Diabetes (self-reported)	0.4	0.7	1.5	-0.1	1.2	-0.1	0.8	0.9	-0.0	1.0	1.0	-0.1	1.2	1.0	1.0	0.5
Time employed in main current job	0.4	0.4	2.3	0.2	-0.2	-0.7	0.4	-0.7	-1.5	0.5	1.0	1.0	-0.2	0.1	-0.2	-0.3
Hair/balding pattern: Pattern 3	0.4	0.6	2.7	-1.1	-0.2	-1.0	0.2	-0.2	-1.6	-1.2	-1.0	-0.2	0.0	-0.0	0.0	0.5
Noisy workplace	0.4	0.5	2.6	-0.6	-0.3	-0.7	-1.6	-0.2	-0.3	-0.8	-0.8	-1.2	0.3	-0.2	0.2	-0.3
Pulse wave reflection index	0.4	0.5	1.7	0.4	-0.8	0.1	-1.0	-1.1	-0.6	-0.4	0.0	-0.7	-0.8	-1.3	-0.7	-0.4
Headache pain in last month	0.4	0.7	1.8	1.4	1.2	0.9	-0.6	1.1	1.2	-0.2	0.4	0.5	0.5	-0.8	-0.4	0.6
Glaucoma (self-reported)	0.4	0.5	1.0	-0.1	1.0	-0.5	0.8	1.0	0.2	-0.0	-0.1	0.9	1.0	0.7	0.7	1.0
Mean time to correctly identify matches	0.4	0.7	2.5	0.8	0.2	-0.7	0.5	-0.2	-0.1	0.3	1.1	0.9	-1.1	-0.8	-1.1	-1.6
Pulse rate, automated reading	0.4	1.2	4.2	-1.7	-0.5	0.3	-0.6	-1.5	-2.1	0.6	-0.1	-1.2	-1.2	0.2	-1.3	-0.7
Alcohol intake frequency.	0.4	0.9	7.7	-0.4	0.2	2.8	-0.1	-0.0	0.7	0.9	1.1	0.2	-0.3	-1.0	-0.1	0.0
Chest pain or discomfort	0.4	0.6	2.6	0.5	-0.5	-0.7	0.5	0.2	-0.1	-0.1	-0.2	-0.6	1.6	1.3	0.8	1.1
Knee pain experienced in last month	0.4	0.6	2.4	-0.6	-0.4	0.3	-0.7	-0.1	0.4	-1.0	-0.9	-1.3	0.9	0.2	0.5	1.6
Average weekly red wine intake	0.4	0.6	1.6	1.1	-0.0	-0.9	-0.1	0.2	0.8	-0.9	-0.7	-0.9	1.3	0.5	0.3	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.1	0.9	0.9	-0.3	-0.3	1.0	0.2	-0.5	-0.4	-0.5	1.0	-0.2	1.0	0.8
Friendships satisfaction	0.4	0.5	2.1	1.1	0.6	1.4	0.8	0.7	-0.2	0.2	0.4	0.8	0.4	0.1	0.5	-0.7
Breast cancer (self-reported)	0.4	0.5	1.6	-0.5	0.6	0.3	-1.1	0.6	0.2	-1.3	-0.9	-0.5	-0.2	-1.0	-0.7	0.2
Medication: Gliclazide	0.4	0.4	2.5	1.6	-0.0	0.4	0.5	0.1	-0.6	0.3	0.3	0.4	0.9	0.8	-0.4	-0.1
Mother’s age at death	0.4	0.5	2.0	-0.4	-1.3	0.2	-0.2	-1.4	-0.8	-0.7	-0.3	-0.8	0.1	0.2	-0.5	0.9
Commuting to job workplace: Public transport	0.4	0.5	4.0	0.8	0.7	-0.1	0.8	0.5	0.4	0.6	0.1	2.0	0.1	0.1	0.0	-0.5
Medication: Paracetamol	0.4	0.6	2.8	0.3	-0.5	-1.7	0.1	-0.5	-0.8	1.1	0.9	-0.0	0.2	0.7	-0.2	1.2
Medication: Atorvastatin	0.4	0.4	1.4	-0.8	-0.4	-0.8	0.4	0.1	-0.3	-0.0	0.2	1.0	0.8	0.8	1.2	0.6
Leg fat percentage (left)	0.4	1.5	4.4	-1.7	-1.9	-1.0	-0.9	-1.7	-2.1	0.9	0.7	-1.2	-0.4	-0.5	-0.9	-0.2
Age started oral contraceptive pill	0.4	0.4	1.5	0.6	-0.5	0.6	0.7	-0.3	0.3	0.9	0.8	0.1	-0.4	1.2	-0.6	-0.7
Myopia	0.4	0.6	1.5	-1.2	-1.1	0.5	-0.2	-0.7	-0.8	0.7	0.4	-0.8	0.5	0.8	0.3	1.0
Depression (Nagel 2018)	0.3	0.5	1.3	0.1	1.1	1.1	-0.1	1.1	0.9	-0.1	-0.2	-0.2	0.3	-0.4	1.0	0.8
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.8	0.7	0.0	0.7	0.8	0.6	1.0	0.7	0.3	0.3	1.6	1.1	1.0	2.0
Fasting Glucose	0.3	0.4	1.2	0.0	0.9	1.0	-0.8	0.6	0.8	-0.0	-0.6	1.1	0.0	-0.1	0.3	-0.4
Rheumatoid Arthritis	0.3	0.5	2.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.4	-1.7	-1.0	-0.7
Systolic blood pressure, automated reading	0.3	0.8	4.6	-0.2	0.9	-0.2	-1.1	0.1	0.4	-1.2	-1.1	-2.2	0.3	0.2	0.3	0.4
Townsend deprivation index at recruitment	0.3	0.4	2.0	0.8	1.4	0.3	-0.3	0.8	0.4	0.6	0.0	0.2	0.5	-0.3	0.4	0.1
Sitting height	0.3	1.9	6.4	-1.8	-2.1	1.1	-0.3	-1.1	-1.2	-1.0	-0.3	0.7	-2.5	-1.8	-1.4	-0.1
Body mass index (BMI)	0.3	1.1	2.7	-0.7	-1.5	-0.8	-0.6	-1.7	-1.6	0.7	0.8	-1.6	-0.1	-0.0	-1.2	-0.2
Waist circumference	0.3	1.2	3.2	-0.3	-1.8	-0.8	-0.9	-1.5	-1.5	0.9	0.5	-1.8	-0.7	-0.3	-1.2	-0.5
Number of incorrect matches in round	0.3	0.5	1.6	0.8	0.2	-0.9	-0.1	-0.5	-0.0	-0.5	-0.2	1.3	-1.0	-0.7	-0.4	-1.1
Past tobacco smoking	0.3	0.5	1.3	-0.4	-0.6	-1.1	-0.8	-0.8	-1.1	-0.8	-0.8	-0.6	0.3	-0.3	0.1	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.1	-0.1	0.2	0.2	-0.3	0.3	1.5	-0.8	-1.1	-1.2	-0.2	-0.3	0.2	0.9
Medication: Lansoprazole	0.3	0.4	1.4	-1.0	-0.3	-1.2	-0.2	-0.4	-0.6	-0.6	-0.4	-0.1	-0.8	0.5	-0.4	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.4	0.4	1.0	0.1	0.3	0.8	1.2	0.3	0.9	0.5	0.5	-0.1	0.3	-0.5
Medication: Amlodipine	0.3	0.4	1.6	-1.3	-0.6	-0.2	-0.4	-0.6	-0.3	0.0	0.0	-0.4	-1.0	0.1	-0.4	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.5	-0.4	0.6	0.1	-0.6	-0.2	-0.5	-0.9	-0.4	0.9	0.7	0.5	1.3
Neck or shoulder pain in last month	0.3	0.4	1.4	1.2	0.5	-0.0	-1.2	0.3	0.4	-0.6	0.1	0.4	0.6	-0.6	0.3	1.0
Medication: Seretide 50 evohaler	0.3	0.4	1.1	-0.2	0.1	0.7	-0.0	0.3	0.6	1.0	0.7	-0.2	0.7	1.1	0.5	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	3.0	-0.1	0.0	-1.7	0.0	-0.1	-0.5	-0.3	-1.0	-0.3	0.3	0.5	0.6	0.1
Leg fat mass (right)	0.3	1.2	3.0	-1.1	-1.7	-0.3	-1.0	-1.5	-1.7	0.8	0.7	-1.7	-0.3	-0.6	-1.1	-0.0
Age at last live birth	0.3	0.5	3.5	1.9	0.6	0.3	0.6	0.8	0.5	-0.3	-0.4	0.5	0.4	-0.3	0.5	-0.4
Medication: Aspirin	0.3	0.4	1.3	0.3	-0.8	0.1	0.3	-0.6	-0.2	0.8	0.4	0.8	-0.7	0.0	-1.1	-0.8
Smoking status: Previous	0.3	0.5	1.1	0.3	-0.1	0.8	0.7	0.2	1.0	1.0	1.0	1.0	-0.2	0.5	-0.2	-0.8
Commuting to job workplace: Walk	0.3	0.3	0.7	0.6	0.5	-0.4	-0.7	0.4	0.5	-0.4	-0.6	-0.6	-0.1	-0.7	0.8	0.8
Number of self-reported non-cancer illnesses	0.3	0.6	1.7	0.8	0.8	-0.0	-1.1	1.0	0.6	-0.3	-0.4	-0.7	0.6	-0.1	0.7	1.3
Guilty feelings	0.3	0.5	1.9	0.5	-0.5	1.2	-0.8	0.2	1.4	-0.3	-0.6	-0.0	0.9	0.2	0.6	0.2
Wears glasses or contact lenses	0.3	0.3	1.0	1.0	-0.4	0.2	-0.8	-0.3	0.2	-0.7	-0.7	-0.8	-0.1	-0.3	-0.3	-0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.9	-1.4	-0.5	-0.3	-0.6	-0.2	-0.7	-0.1	-0.4	-0.7	-0.3	-0.2	-0.1	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.5	-0.2	-0.7	-0.3	-1.0	-0.5	-0.4	0.1	0.6	1.2	-0.1	-0.4	0.1	0.7
Impedance of whole body	0.3	1.6	3.6	0.9	1.3	0.6	-1.2	1.9	1.6	-1.1	-1.8	0.3	0.4	-1.1	1.8	1.2
Leg fat mass (left)	0.3	1.1	3.3	-1.0	-1.6	-0.4	-0.9	-1.4	-1.6	0.7	0.7	-1.8	-0.3	-0.4	-0.9	0.2
Reaction Time	0.2	0.4	1.1	0.3	0.2	-0.2	0.3	-0.0	0.4	0.2	0.9	1.0	-0.9	-1.1	-0.9	-0.7
Mean Putamen Volume	0.2	0.2	1.4	-0.1	0.0	-0.0	-0.2	0.2	-0.7	-0.1	0.1	-1.2	0.1	-0.5	0.0	-0.6
BMI	0.2	1.0	2.3	-0.5	-1.5	-0.5	-0.0	-1.5	-1.4	1.3	1.2	-0.9	0.1	0.6	-1.4	-0.1
Cardiovascular Disease	0.2	0.5	1.8	0.7	-0.2	-1.3	-0.6	-0.2	-0.1	0.8	0.7	0.7	0.9	0.8	0.6	1.0
Hair Pigment	0.2	4.9	8.9	2.8	3.0	0.2	1.9	2.6	2.6	2.7	2.4	1.6	2.1	2.1	2.1	0.6
Number of treatments/medications taken	0.2	0.3	1.3	0.2	0.2	-1.0	-0.4	0.3	-0.2	0.9	1.1	0.4	0.1	0.7	0.1	0.2
Trunk fat percentage	0.2	0.6	2.4	-0.4	-1.1	0.0	-1.4	-0.6	-0.7	0.4	-0.1	-1.6	-0.1	-0.9	-0.5	0.5
Qualifications: CSEs or equivalent	0.2	0.3	0.9	-0.4	-0.6	0.6	0.0	-0.6	0.0	0.7	0.5	0.1	0.3	0.7	-1.0	-0.7
Impedance of leg (left)	0.2	0.7	2.7	-0.6	0.6	-0.9	-0.8	0.9	-0.1	-0.7	-1.2	1.1	0.0	-0.4	1.6	0.7
Hip circumference	0.2	1.0	3.5	0.6	-1.4	0.0	0.2	-1.0	-1.1	1.9	1.9	-0.3	-0.0	-0.2	-1.0	0.3
Father’s age at death	0.2	0.2	1.5	0.0	0.0	0.6	0.2	-0.4	-0.2	-0.1	-0.2	-0.1	-1.2	0.6	-0.5	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.8	-0.2	0.0	0.6	-0.8	-0.4	-0.2	-0.6	-0.2	-0.9	-0.1	-0.3	-0.9	-0.4
Standing height	0.2	2.1	11.0	2.1	0.7	3.3	-0.1	1.6	1.8	-0.3	0.0	0.3	-0.2	-1.1	1.0	1.9
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.4	-0.8	-0.1	-0.4	0.3	-0.3	-0.3	0.2	0.5	0.6	0.2	0.0	0.3	1.2
Medication: Paracetamol	0.2	0.3	1.6	-0.0	-0.1	-1.3	-0.5	-0.6	-0.7	0.2	-0.0	-0.5	-0.4	-0.1	-0.5	0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.9	0.3	0.7	0.9	-0.0	0.4	0.7	-0.7	-0.3	0.1	-0.3	-0.9	-0.1	0.3
Body fat percentage	0.2	0.7	2.0	-0.7	-1.2	-0.1	-1.1	-1.0	-1.1	0.7	0.3	-1.4	-0.1	-0.7	-0.7	0.2
Arm fat-free mass (right)	0.2	1.0	2.6	-0.6	-1.6	-0.1	0.2	-1.4	-1.6	0.6	1.0	-0.5	-1.3	-0.2	-1.3	-0.2
Exposure to tobacco smoke outside home	0.2	0.3	2.1	1.4	-0.3	-0.4	-0.2	-0.5	0.6	0.5	0.3	-0.0	0.3	-0.5	0.0	0.0
Comparative body size at age 10	0.2	0.7	3.4	0.3	0.8	-0.2	0.1	1.0	-0.4	0.2	0.3	-0.9	1.8	0.4	1.0	1.1
Number of full brothers	0.2	0.3	1.0	0.1	1.0	0.4	-0.2	0.8	-0.6	0.0	0.2	-0.4	-0.3	-0.7	0.5	0.3
Qualifications: College or University degree	0.2	0.7	3.2	1.8	-0.2	-1.7	0.5	0.4	0.5	0.5	0.4	0.2	0.8	0.4	0.8	0.7
Medication: Ibuprofen	0.2	0.2	1.0	-0.2	0.4	-0.5	0.1	-0.0	-0.1	0.7	1.0	-0.3	0.3	0.5	-0.6	-0.5
Medication: Omeprazole	0.2	0.3	1.4	-0.4	0.0	-0.4	-0.6	-0.0	-0.5	0.3	0.7	1.2	-0.3	-0.3	0.2	0.5
Whole body fat mass	0.2	0.7	2.2	-0.5	-1.4	0.3	-0.8	-1.0	-1.1	0.8	0.6	-1.5	-0.1	-0.4	-0.7	0.5
Arm predicted mass (right)	0.2	0.8	1.9	-0.4	-1.4	0.2	0.4	-1.2	-1.4	0.8	1.3	-0.4	-1.1	0.0	-1.1	-0.1
Hypertension (Self-reported)	0.2	0.5	1.2	0.9	-0.9	-0.9	-0.5	-0.3	-0.2	0.8	0.6	-0.4	0.6	1.1	-0.2	0.6
Back pain experienced in last month	0.2	0.3	0.8	0.3	0.3	0.4	-0.9	0.6	0.2	-0.6	-0.3	-0.3	0.6	0.8	0.5	-0.0
Medication: Aspirin	0.2	0.3	0.6	0.7	-0.6	-0.4	0.2	-0.4	-0.3	0.7	0.4	0.8	-0.3	0.1	-0.6	-0.5
Eye problems/disorders: Glaucoma	0.2	0.3	1.0	-0.8	0.1	0.1	1.0	0.2	-0.9	0.4	0.3	0.7	0.2	0.2	-0.1	0.1
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.9	-1.4	0.5	0.4	0.4	-0.0	-0.1	-0.8	-0.8	0.0	-0.9	-1.2	-0.4	-0.7
HbA1C	0.1	0.1	0.5	0.2	0.2	-0.0	0.1	-0.2	0.3	-0.3	0.0	-0.1	-0.0	-0.2	-0.1	-0.7
Neuroticism (2016)	0.1	0.2	1.1	-0.2	-0.1	0.3	-0.5	-0.3	1.1	0.3	-0.2	-0.5	-0.3	0.2	0.4	0.4
Height	0.1	2.0	10.7	1.4	-0.3	2.4	-1.1	0.6	0.0	-0.8	0.1	0.4	-1.7	-3.3	0.5	1.2
Systolic Blood Pressure	0.1	0.7	2.4	0.2	0.7	-1.0	-0.4	0.3	0.5	-0.8	-0.9	-1.6	0.9	0.9	0.9	0.7
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	-0.0	0.3	0.1	0.3	0.5	0.2	0.7	0.8	0.0	0.4	0.6	0.4	0.1
Tanning	0.1	1.6	5.6	1.2	0.3	0.6	0.7	0.5	0.5	0.9	0.1	1.2	2.4	2.2	1.4	1.7
Supplements: Zinc	0.1	0.1	0.4	-0.6	0.2	0.4	0.2	0.5	0.1	-0.4	0.1	-0.1	-0.1	-0.3	0.2	-0.3
Impedance of leg (right)	0.1	0.6	1.7	-0.8	0.6	-0.4	-0.7	0.8	-0.3	-0.7	-1.0	1.2	-0.1	-0.7	1.3	0.1
Leg fat-free mass (left)	0.1	0.7	3.0	0.2	-0.8	1.7	0.1	-0.5	-0.2	0.7	1.1	-1.2	-0.3	-0.4	-1.2	0.3
High blood pressure	0.1	0.3	1.0	0.9	-0.9	-0.7	-1.0	-0.3	-0.1	0.3	0.1	-0.5	0.3	0.7	-0.3	0.2
Leg predicted mass (left)	0.1	0.7	3.2	0.2	-0.8	1.8	0.1	-0.5	-0.2	0.7	1.1	-1.2	-0.3	-0.4	-1.2	0.4
Trunk fat mass	0.1	0.6	1.8	-0.4	-1.2	0.4	-1.0	-0.8	-0.9	0.8	0.5	-1.3	-0.3	-0.8	-0.7	0.5
Financial difficulties in last 2 years	0.1	0.2	1.0	0.0	-0.0	-0.3	0.3	-0.4	-0.6	-0.6	-0.4	0.3	0.2	0.3	-0.1	-1.0
Weight	0.1	0.7	1.7	0.1	-1.3	0.7	-0.5	-1.0	-0.9	0.7	0.9	-1.3	-0.3	-0.5	-0.9	0.6
Arm fat percentage (right)	0.1	0.4	1.8	-0.0	-0.6	0.5	-0.9	-0.5	-0.3	0.9	0.6	-1.3	0.2	-0.5	-0.6	0.2
Trunk fat-free mass	0.1	0.7	3.3	0.2	-0.7	1.2	1.0	-0.5	-0.6	1.2	1.8	0.4	-0.5	0.3	-0.7	0.1
Mouth/teeth dental problems: Dentures	0.1	0.3	0.8	0.2	-0.4	-0.7	-0.1	-0.0	-0.1	0.6	0.5	-0.3	0.9	0.7	-0.2	-0.7
Illnesses of mother	0.1	0.2	0.7	0.5	0.3	0.4	-0.4	0.1	0.2	-0.2	-0.8	-0.1	-0.4	-0.7	0.1	0.1
Arm fat mass (right)	0.1	0.5	2.1	0.0	-0.8	0.6	-0.8	-0.6	-0.4	0.8	0.8	-1.5	0.3	-0.3	-0.5	0.6
Trunk predicted mass	0.1	0.7	3.5	0.2	-0.7	1.3	1.1	-0.4	-0.6	1.2	1.9	0.5	-0.5	0.4	-0.6	0.2
High blood pressure (siblings)	0.1	0.2	0.9	0.4	0.3	-0.1	-0.3	0.5	-0.0	0.4	0.6	0.2	-0.6	0.2	-0.0	-1.0
Medication for pain relief, constipation, heartburn	0.1	0.2	0.7	-0.2	0.1	0.3	0.9	0.4	0.3	-0.3	-0.2	-0.3	0.2	0.1	0.6	-0.7
Medication: Blood pressure	0.1	0.1	0.5	-0.2	-0.1	-0.1	0.1	0.3	0.3	0.6	0.2	-0.6	0.4	0.7	0.3	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.0	0.2	-0.4	0.3	-0.3	0.3	-0.1	-0.0	-0.0	-0.8	-0.5	-1.0	0.1	0.5
Whole body fat-free mass	0.1	0.7	2.3	0.1	-0.9	1.4	0.6	-0.6	-0.6	1.0	1.5	-0.3	-0.6	0.1	-1.0	0.1
Leg fat-free mass (right)	0.1	0.7	2.5	0.5	-0.9	1.6	0.2	-0.5	-0.1	0.7	1.1	-1.1	-0.3	-0.2	-1.2	0.5
Arm fat percentage (left)	0.1	0.5	2.6	-0.1	-0.8	0.5	-1.1	-0.6	-0.3	0.7	0.3	-1.6	0.0	-0.8	-0.8	0.3
Whole body water mass	0.1	0.6	2.0	0.1	-1.0	1.3	0.6	-0.7	-0.7	0.9	1.4	-0.3	-0.6	0.1	-1.0	0.1
Leg predicted mass (right)	0.1	0.7	2.6	0.5	-0.9	1.6	0.2	-0.5	-0.1	0.8	1.1	-1.1	-0.3	-0.2	-1.2	0.6
Arm fat mass (left)	0.1	0.6	2.5	0.1	-0.9	0.4	-1.0	-0.7	-0.5	0.7	0.6	-1.6	-0.1	-0.6	-0.7	0.5
Ever smoked	0.1	0.3	0.9	0.6	0.2	0.3	1.0	0.4	0.6	0.8	0.8	0.3	0.1	0.5	-0.1	0.2
Basal metabolic rate	0.1	0.6	1.9	0.1	-0.9	1.2	0.4	-0.6	-0.6	0.9	1.4	-0.6	-0.4	-0.1	-0.9	0.3
Arm fat-free mass (left)	0.1	0.6	1.8	-0.3	-1.4	0.3	0.2	-1.1	-1.2	0.6	1.1	-0.5	-0.7	0.3	-0.8	0.2
Pain experienced in last month	0.1	0.2	0.9	0.6	-0.0	0.3	0.9	0.2	0.4	0.3	-0.5	0.5	-0.1	0.4	0.3	-0.9
Arm predicted mass (left)	0.1	0.5	1.4	-0.2	-1.2	0.4	-0.0	-1.0	-1.2	0.3	0.8	-0.7	-0.7	0.2	-0.8	0.2
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ABCA7

Models

Trait associations