TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Crohns Disease (2017)
:
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chr19:9,829,303-11,376,675
Best TWAS P=3.7e-10 · Best GWAS P=2.84e-13 conditioned to 9.42e-11
9.8M
10M
10.2M
10.4M
10.6M
10.8M
11M
11.2M
11.4M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
CDKN2D
0.16
0.08
lasso
10
0.11
3.5e-35
4.9
-6.3
3.7e-10
0.07
1.00
0.00
TRUE
1
GTEx
Testis
PDE4A
0.20
0.02
enet
39
0.04
6.4e-03
6.0
6.1
8.4e-10
-0.11
0.05
0.21
TRUE
3
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
S1PR5
0.05
0.04
lasso
4
0.04
5.2e-04
3.6
-5.5
2.9e-08
0.32
0.03
0.32
FALSE