Best TWAS P=3.7e-10 · Best GWAS P=2.84e-13 conditioned to 9.42e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | PDE4A | 0.20 | 0.02 | enet | 39 | 0.04 | 6.4e-03 | 6.0 | 6.1 | 8.4e-10 | -0.11 | 0.05 | 0.21 | TRUE |
| 2 | YFS | Blood | CDKN2D | 0.16 | 0.08 | lasso | 10 | 0.11 | 3.5e-35 | 4.9 | -6.3 | 3.7e-10 | 0.07 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | S1PR5 | 0.05 | 0.04 | lasso | 4 | 0.04 | 5.2e-04 | 3.6 | -5.5 | 2.9e-08 | 0.32 | 0.03 | 0.32 | FALSE |