TWAS hub - POLR2E

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2260	0.0400	1.3e-09	0.139	0.115	0.150	0.168	0.155	1.6e-16	7.9e-14	7.1e-18	5.2e-20	1.9e-18
2	GTEx	Artery Aorta	0.3600	0.0660	9.0e-06	0.101	NA	0.270	NA	0.303	3.5e-06	NA	3.5e-15	NA	3.7e-17
3	GTEx	Artery Tibial	0.3526	0.0502	2.5e-09	0.255	NA	0.271	NA	0.260	5.6e-20	NA	2.5e-21	NA	2.0e-20
4	GTEx	Breast Mammary Tissue	0.3950	0.0810	7.5e-05	0.059	NA	0.143	NA	0.156	5.8e-04	NA	8.7e-08	NA	2.1e-08
5	GTEx	Cells Transformed fibroblasts	0.2000	0.0510	3.0e-04	0.087	NA	0.158	NA	0.163	4.4e-07	NA	6.2e-12	NA	2.7e-12
6	GTEx	Colon Sigmoid	0.3420	0.0940	2.0e-03	0.077	NA	0.148	NA	0.109	1.1e-03	NA	6.9e-06	NA	1.2e-04
7	GTEx	Esophagus Muscularis	0.3770	0.0680	1.3e-06	0.177	NA	0.197	NA	0.156	5.8e-11	NA	3.9e-12	NA	9.6e-10
8	GTEx	Nerve Tibial	0.2536	0.0596	2.0e-04	0.055	NA	0.113	NA	0.131	9.1e-05	NA	2.3e-08	NA	1.6e-09
9	GTEx	Thyroid	0.2240	0.0590	8.0e-04	0.157	NA	0.125	NA	0.147	4.3e-12	NA	8.9e-10	NA	2.4e-11
10	GTEx	Whole Blood	0.1030	0.0390	8.1e-03	-0.002	NA	0.001	NA	0.000	6.9e-01	NA	2.3e-01	NA	3.3e-01
11	ROSMAP	Brain Pre-frontal Cortex	0.2853	0.0345	0.0e+00	0.274	0.232	0.289	0.284	0.292	2.5e-35	1.8e-29	1.8e-37	1.1e-36	6.6e-38
12	YFS	Blood	0.2044	0.0272	0.0e+00	0.131	0.133	0.159	0.160	0.148	1.7e-40	3.9e-41	1.8e-49	7.8e-50	5.3e-46
13	TCGA	Breast Invasive Carcinoma	0.0401	0.0174	4.6e-04	0.006	0.023	0.029	NA	0.019	2.0e-02	1.2e-05	1.2e-06	NA	6.2e-05
14	TCGA	Brain Lower Grade Glioma	0.0567	0.0265	6.0e-03	0.018	0.017	0.007	NA	0.006	3.3e-03	4.2e-03	4.7e-02	NA	5.8e-02
15	TCGA	Prostate Adenocarcinoma	0.0628	0.0246	3.1e-04	-0.001	0.032	0.010	NA	0.006	4.9e-01	2.3e-04	2.7e-02	NA	7.5e-02
16	TCGA	Thyroid Carcinoma	0.1380	0.0460	5.8e-08	0.079	0.078	0.096	NA	0.099	4.3e-08	4.7e-08	1.4e-09	NA	7.3e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Crohns Disease (2017)	8.1	17.8	65.8	-5.2	-4.5	-4.7	-8.1	-2.3	-2.5	-4.2	-4.6	-0.2	-4.3	-4.5	1.5	-1.6	-1.9	-5.2	-5.0
Irritable Bowel Disease (IBD)	7.0	16.7	51.9	-4.7	-4.5	-4.6	-7.2	-2.5	-2.9	-3.2	-4.3	-0.4	-4.3	-4.9	2.0	-3.0	-2.0	-5.6	-4.3
Blood White Count	5.8	43.3	75.3	-5.1	-8.2	-8.2	-8.4	-4.1	-4.8	-7.1	-7.9	-3.1	-5.7	-7.5	5.6	-5.0	-7.7	-8.7	-4.6
Alzheimer’s Disease (including proxy)	5.3	7.7	20.2	3.9	3.4	3.8	2.8	0.7	1.3	3.6	3.1	0.5	2.2	4.0	-0.0	-0.5	4.5	2.6	0.3
Wheeze or whistling in the chest in last year	4.5	8.0	17.2	1.0	4.1	2.7	2.4	2.7	-0.1	1.8	3.8	2.6	3.1	2.6	-2.5	2.0	3.6	4.1	2.9
Average weekly spirits intake	3.2	4.0	10.7	-2.3	-2.0	-2.6	-3.3	-0.6	-1.6	-1.9	-2.3	0.6	-2.7	-2.0	2.7	-1.0	-0.1	-2.0	-1.1
Eye problems/disorders: None of the above	3.1	3.6	9.7	-1.5	-2.4	-2.4	-3.1	-2.2	-1.3	-2.6	-2.6	-1.6	-1.3	-1.4	0.3	0.3	-1.4	-2.0	-1.1
Sensitivity / hurt feelings	2.8	4.8	12.2	-0.7	2.9	1.9	1.7	2.0	0.7	1.2	2.1	1.9	0.3	2.1	-2.7	3.5	2.9	2.8	2.8
Lupus	2.7	4.0	14.1	3.4	2.0	3.1	3.8	0.3	1.5	1.2	2.4	-0.8	0.6	2.9	-0.7	0.5	0.4	1.6	-1.9
Diabetes (father)	2.7	3.3	14.3	1.9	-2.1	0.3	-0.7	-3.8	-0.5	-1.8	-1.9	-2.9	2.2	1.0	-0.7	1.0	-1.3	-0.9	-2.2
Basal cell carcinoma (self-reported)	2.7	3.2	9.0	0.2	-2.3	-1.6	-2.1	-2.7	0.1	-0.8	-2.0	-1.9	-1.8	-1.2	0.9	-1.1	-1.8	-3.0	-2.2
Current tobacco smoking	2.6	4.3	8.6	1.0	2.8	2.0	2.1	2.2	0.4	2.1	2.3	1.8	2.3	2.1	1.6	0.9	2.2	2.9	2.7
Average weekly red wine intake	2.4	3.5	13.2	-0.1	2.5	0.8	0.8	3.5	1.4	1.1	1.7	3.6	-1.8	0.4	0.6	1.9	1.8	1.9	1.6
Serious illness, injury or assault to yourself	2.3	2.8	6.8	1.2	1.9	1.8	2.3	0.9	0.8	2.6	1.5	0.7	1.3	1.9	-1.6	1.0	1.8	2.3	1.6
Pain all over the body in last month	2.3	2.5	5.8	0.5	2.0	1.8	1.8	0.8	0.3	1.8	1.3	0.7	1.4	2.2	-1.0	1.9	1.1	2.0	2.4
Gout (self-reported)	2.3	3.1	6.5	-1.6	-2.6	-2.1	-0.9	-2.1	-0.7	-0.6	-2.2	-2.1	-1.8	-1.8	1.0	-1.9	-1.6	-2.2	-1.5
Average weekly beer plus cider intake	2.3	3.3	7.4	2.0	2.3	2.4	2.3	0.9	1.9	1.6	2.5	0.0	2.3	1.8	-0.9	1.0	0.8	2.7	1.1
Mouth/teeth dental problems: Mouth ulcers	2.2	3.6	13.0	-2.1	-1.2	-2.6	-3.1	0.5	-3.6	-2.0	-1.4	1.6	-2.0	-2.6	0.6	0.1	-0.1	-0.9	0.7
Blood Eosinophil Count	2.1	15.9	54.9	-7.4	1.3	-4.2	-0.3	6.8	-3.3	-2.9	2.2	5.3	1.4	-6.5	0.6	-0.7	1.0	2.1	5.6
Alcohol drinker status: Previous	2.0	2.3	10.2	-0.5	2.3	0.8	0.8	1.6	0.1	0.6	1.8	1.8	0.6	1.2	-1.1	1.1	3.2	2.3	1.1
Alzheimer’s Disease (in mother)	1.9	2.2	5.7	1.6	1.8	1.8	1.6	0.7	0.6	1.9	2.1	0.4	1.7	1.4	0.5	-1.1	2.4	1.5	0.7
Frequency of depressed mood in last 2 weeks	1.9	2.6	8.9	0.9	2.2	2.0	0.7	0.8	0.2	1.3	1.8	1.4	0.1	2.4	-2.0	0.4	3.0	1.9	1.3
Allergy	1.9	4.3	11.1	3.3	1.5	2.8	3.2	0.9	3.3	2.6	1.9	-0.1	2.8	2.0	1.0	-0.9	0.0	1.3	-0.1
Illnesses of siblings	1.9	2.7	6.2	1.2	2.2	1.9	0.0	1.4	2.1	1.2	1.5	2.1	-0.8	1.8	-0.1	1.8	2.5	2.2	0.7
Heart disease (mother)	1.9	2.3	8.6	0.0	-2.2	-1.1	-1.5	-2.9	-1.4	-1.3	-2.1	-2.2	-1.0	-0.4	0.6	0.7	-1.6	-1.6	-0.6
Prostate Cancer	1.8	2.5	6.2	0.9	1.1	1.9	1.0	-1.2	2.3	2.5	1.1	-1.9	1.1	2.4	-1.4	1.2	0.0	1.0	2.1
Hayfever, allergic rhinitis or eczema	1.8	4.0	10.2	-3.1	-1.7	-2.6	-3.2	-0.4	-2.4	-3.0	-1.6	0.5	-2.6	-2.2	-0.7	0.7	-0.8	-1.8	-0.8
Alcohol intake versus 10 years previously	1.8	2.7	7.5	-0.9	-2.7	-1.9	-1.2	-1.6	-1.5	-2.2	-2.5	-1.5	-0.2	-1.5	0.1	-1.0	-1.6	-1.6	-1.9
Unable to work because of sickness or disability	1.8	2.4	8.2	1.8	1.3	2.3	1.6	-0.6	0.1	1.9	0.9	-0.5	1.0	2.9	-1.0	1.8	1.7	1.7	0.9
Allergy or Eczema	1.7	4.4	12.0	-2.9	-1.5	-2.8	-3.5	0.1	-2.6	-3.1	-1.4	1.1	-2.7	-2.6	0.4	-0.3	-0.4	-1.9	-1.3
Father’s age at death	1.7	2.3	6.7	0.0	-2.3	-1.0	-1.3	-1.5	-0.4	-0.3	-2.4	-1.3	-0.9	-0.3	2.4	0.5	-2.6	-2.0	-1.1
Supplements: Vitamin C	1.7	2.0	6.9	0.7	-1.5	-0.6	-0.8	-1.9	0.1	0.2	-1.3	-1.6	-2.1	-0.5	1.3	-1.0	-2.6	-2.2	-0.9
Smoking status: Current	1.7	2.6	5.4	0.7	2.2	1.5	1.5	1.9	0.1	1.5	1.6	1.7	1.5	1.6	1.6	0.7	1.9	2.3	2.2
Ulcerative Colitis (UC)	1.6	3.0	7.7	-2.0	-1.6	-2.1	-2.8	-0.7	-1.5	-0.4	-1.6	0.5	-1.9	-2.6	1.1	-2.3	-0.2	-2.4	-0.9
Relative age of first facial hair	1.6	3.3	11.1	-1.6	-1.7	-2.1	-1.7	0.3	-1.5	-1.6	-1.8	0.7	-1.7	-1.8	1.2	-2.9	0.6	-2.0	-3.3
Medication: Amlodipine	1.6	2.3	8.7	-0.3	-2.2	-1.2	-1.1	-2.3	0.6	-1.1	-1.8	-2.6	0.2	-0.5	-0.3	1.0	-3.0	-1.4	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	6.8	-0.7	1.8	0.9	0.3	1.8	0.4	0.3	1.4	1.5	-1.2	0.6	-0.1	2.4	0.1	1.8	2.6
Hearing aid user	1.6	1.8	5.0	1.7	1.7	2.0	2.1	0.8	0.9	1.4	2.2	0.5	1.5	0.7	-0.7	-1.0	0.8	0.8	-0.4
Blood Red Count	1.5	14.5	34.1	-5.1	-5.4	-5.8	-5.0	-2.4	-3.1	-3.4	-5.7	-1.6	-1.9	-4.2	0.4	-1.3	-2.1	-4.7	-2.3
Number of children fathered	1.5	1.7	5.5	-0.4	1.6	1.0	1.4	2.4	0.9	1.0	1.6	1.8	1.7	0.6	1.0	0.0	0.8	1.3	1.0
Health satisfaction	1.5	2.0	4.7	-1.3	-0.8	-2.2	-1.0	0.9	-1.9	-1.1	-1.1	1.5	-0.8	-2.0	2.0	-2.1	1.2	-0.5	-0.3
Hypothyroidism (self reported)	1.4	3.3	9.7	3.1	-0.2	1.8	2.2	-1.5	0.4	2.3	-0.4	-2.6	1.9	3.1	-0.2	1.9	-1.7	0.0	0.5
Mouth/teeth dental problems	1.4	2.1	7.6	1.6	-0.5	1.2	1.3	-1.8	2.3	1.7	-0.4	-2.8	0.5	1.8	-0.9	-0.8	-0.3	-0.5	-1.8
Length of working week for main job	1.4	1.6	6.0	-1.3	-1.1	-1.7	-0.7	-0.3	-2.1	-1.1	-0.8	-0.0	-0.9	-2.4	1.6	-1.2	-0.5	-1.1	0.6
Comparative body size at age 10	1.4	3.8	6.5	1.2	2.4	2.5	2.5	1.6	1.9	2.1	2.5	0.9	1.6	1.4	-2.3	1.6	0.8	2.4	2.0
Worry too long after embarrassment	1.4	2.3	6.0	0.1	1.9	1.8	0.6	1.1	1.0	0.9	1.6	1.1	-0.4	2.2	-1.6	2.5	2.0	1.8	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	5.0	0.3	1.6	0.8	2.0	2.1	-0.8	0.1	1.4	1.5	0.8	0.7	-0.6	0.8	1.2	2.2	1.7
Medication for hormone replacement therapy	1.3	1.5	7.5	1.0	1.7	1.1	1.1	1.0	0.3	-0.3	1.6	1.4	1.0	0.7	0.1	-0.9	2.7	1.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.8	8.5	1.3	-2.7	-0.9	-0.1	-2.9	0.1	-0.1	-2.3	-2.7	-0.8	-0.1	-0.1	-0.4	-2.1	-2.3	-2.0
Had major operations	1.3	1.5	6.1	-0.3	-1.2	-1.1	0.1	-0.4	-1.5	-0.9	-1.1	-0.5	2.5	-1.1	1.5	-2.0	-0.2	-1.0	-1.4
Illnesses of siblings: Diabetes	1.3	1.6	3.0	-1.6	-1.7	-1.7	-0.8	-0.9	-0.6	-1.4	-1.6	-1.1	-1.0	-1.4	-0.0	-0.6	-1.5	-1.6	-1.2
Cholesterol lowering medication	1.3	1.9	4.5	2.1	1.4	1.8	2.1	0.4	1.1	1.4	1.4	-0.2	1.4	1.8	-0.7	1.1	0.7	1.5	1.3
Age at First Birth	1.2	1.7	4.4	-1.0	1.6	0.6	1.4	2.1	-0.2	0.3	1.4	1.4	2.0	-0.2	1.4	0.0	1.2	1.5	1.9
Hair/balding pattern: Pattern 2	1.2	1.5	3.5	-0.5	-1.8	-1.2	-0.9	-1.3	-0.9	-1.1	-1.5	-1.5	0.1	-0.8	0.4	-1.4	-1.1	-1.9	-1.7
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	4.4	-1.9	-1.0	-1.6	-2.1	-0.3	-1.9	-1.3	-1.4	0.3	-1.9	-1.2	-0.9	0.2	-0.4	-1.2	-0.4
Mouth/teeth dental problems: Dentures	1.2	2.0	7.5	-0.3	1.5	0.2	0.9	2.6	-0.3	-1.2	1.3	2.7	1.6	-0.6	1.1	0.1	0.9	1.8	1.6
Depression (self-reported)	1.2	1.4	3.1	-1.5	-0.7	-1.8	-0.8	1.0	-1.3	-1.7	-1.4	1.7	0.5	-1.7	0.6	-1.3	0.7	-0.0	0.2
Tense / ‘highly strung’	1.2	2.0	14.0	-1.0	-1.5	-1.4	-1.7	-1.0	-1.4	-0.9	-1.9	-0.3	-3.7	-0.5	-0.7	-0.5	0.3	-1.2	-0.8
Birth weight of first child	1.2	2.2	6.6	1.2	1.5	1.7	1.1	0.9	0.5	0.4	0.9	0.7	1.0	2.3	-1.3	2.1	1.3	2.6	2.0
Glaucoma (self-reported)	1.2	1.4	4.9	1.9	0.9	1.2	2.1	0.7	0.3	2.2	1.1	-0.3	0.6	1.1	-0.1	-0.1	0.1	1.2	1.7
Overall health rating	1.2	2.6	9.2	-2.3	0.9	-1.3	-1.4	1.9	-2.4	-1.6	0.1	3.0	-0.8	-0.8	1.1	-0.3	2.4	1.2	1.2
Qualifications: nursing, teaching	1.2	1.9	6.0	-0.0	2.1	1.6	0.9	1.6	1.1	1.2	1.7	1.1	-0.7	1.6	-0.0	1.5	0.8	1.3	2.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	4.2	1.6	1.3	1.4	1.0	0.3	0.8	1.1	0.9	0.4	0.4	2.1	-0.1	-0.1	1.9	1.6	0.6
Medication: Atenolol	1.1	1.4	6.2	2.5	0.6	1.6	1.2	-0.2	1.0	0.9	1.4	-0.8	0.7	1.6	-1.5	1.4	-0.3	0.5	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	9.5	1.7	-2.1	-0.4	0.5	-2.1	0.9	0.2	-1.6	-2.3	-0.9	0.1	-0.3	0.5	-3.1	-2.1	-1.8
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	7.5	0.7	2.0	1.1	0.5	1.2	0.4	1.1	1.6	1.5	0.7	0.9	-1.3	0.3	2.7	1.6	1.6
Impedance of arm (left)	1.1	5.2	23.8	1.0	2.7	2.0	0.3	2.4	3.6	0.9	2.0	3.0	1.4	1.3	0.5	-0.4	4.9	3.1	-0.8
Headache pain in last month	1.1	1.9	6.6	-1.7	1.7	-0.3	-0.5	2.2	-0.6	0.4	1.4	2.6	-0.5	-0.4	-1.0	1.2	1.7	1.1	2.0
Commuting to job workplace: Car/motor vehicle	1.1	1.3	3.1	0.1	1.3	1.1	1.2	1.0	-0.5	1.3	1.8	0.7	0.9	1.1	-0.9	0.4	1.6	1.4	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	4.5	-1.1	0.1	-1.4	-0.4	1.0	-2.1	-0.9	-0.2	1.5	-1.1	-1.6	0.1	-1.3	1.7	0.4	0.3
Illnesses of father: High blood pressure	1.1	1.4	4.9	-1.5	-1.1	-1.9	-1.9	-0.9	-0.4	-2.2	-1.3	-0.0	-0.2	-1.6	-0.7	-0.5	0.3	-0.6	-0.6
Alzheimer’s Disease (in father)	1.0	1.1	4.2	1.9	-0.2	0.8	0.8	-0.8	0.6	2.1	0.2	-0.7	1.3	0.4	1.2	-1.6	0.2	-0.7	-1.0
Heel T-Score	1.0	7.6	31.1	4.4	-1.8	1.4	3.2	-4.0	3.1	2.6	-1.0	-5.6	1.3	2.6	0.6	-0.4	-2.6	-1.5	-2.1
Qualifications: CSEs or equivalent	1.0	1.3	4.3	-2.0	-0.1	-1.3	-1.6	1.1	-1.2	-2.1	-0.3	1.7	0.0	-1.4	0.6	0.4	0.5	0.8	0.0
Nervous feelings	1.0	1.9	12.2	-3.5	0.1	-1.1	-1.4	0.5	-0.3	-1.6	-0.4	0.8	-2.4	-0.4	-1.3	1.8	0.9	0.1	0.3
Asthma	1.0	2.0	6.9	-1.9	0.3	-1.2	-1.5	0.2	-2.6	-0.5	-0.5	1.0	-0.3	-0.2	-1.8	2.2	1.2	0.7	2.4
Medication: Lansoprazole	1.0	1.1	6.3	-1.2	-0.2	-1.0	-1.2	0.2	-1.0	-1.5	-1.1	0.7	-2.5	-0.5	1.3	-0.4	-0.4	-0.5	0.2
High blood pressure (siblings)	1.0	1.5	4.5	-0.9	-1.5	-1.3	-0.0	-0.7	-0.9	-1.0	-1.3	-1.5	0.5	-0.8	1.6	-1.1	-2.1	-1.7	-0.3
Shortness of breath walking on level ground	1.0	1.2	3.6	-0.6	0.8	-0.6	0.8	1.8	-1.2	0.6	0.7	1.1	0.5	-0.5	0.5	-0.4	1.5	1.9	1.9
Medication for cholesterol	1.0	1.6	5.6	-1.4	-1.5	-1.2	-1.3	-0.8	0.1	0.3	-1.4	-0.7	-2.1	-1.1	-0.1	0.8	-2.4	-1.5	-0.2
Asthma (self-reported)	1.0	2.0	8.9	-2.0	0.1	-1.4	-1.7	-0.1	-3.0	-1.0	-0.7	0.7	-0.4	-0.4	-1.5	1.9	1.0	0.4	2.2
Tinnitus: Yes, now most or all of the time	1.0	1.1	3.7	-0.6	-1.0	-1.3	-1.4	-0.5	-1.4	-0.7	-1.0	0.3	-1.9	-1.4	0.2	-1.4	0.6	-0.9	-0.3
Supplements: Fish oil (including cod liver oil)	1.0	1.2	5.2	-0.8	-1.3	-1.3	-1.2	-0.7	-0.6	0.1	-1.4	-0.3	-2.3	-1.0	0.3	-0.8	-1.1	-1.7	-0.4
Heart disease (siblings)	1.0	1.2	8.0	-1.1	0.2	-1.1	0.6	0.6	-2.8	-1.1	0.6	0.1	-0.9	-1.3	-1.2	0.1	-0.1	0.4	1.5
Respiratory disease	0.9	2.0	6.6	-1.8	0.2	-0.8	-0.9	-0.6	-2.5	-1.0	-0.7	-0.0	0.3	0.2	-1.9	2.6	1.2	1.3	2.3
Hearing difficulty/problems: Yes	0.9	1.4	3.4	-0.8	1.8	0.7	0.5	1.8	-1.0	1.0	1.5	1.6	-0.8	0.3	-1.8	1.3	0.4	0.5	1.3
Maternal smoking around birth	0.9	1.3	3.5	1.6	1.0	1.6	1.4	0.4	-0.1	1.0	1.3	0.4	1.4	1.2	-0.8	-0.2	1.7	1.9	-0.4
Supplements: Glucosamine	0.9	1.1	8.1	-1.0	-0.7	-0.7	-1.4	-0.8	-0.5	-1.1	-0.7	-0.3	-2.8	-0.3	-0.7	-0.1	-0.5	-1.4	-0.7
Medication: Levothyroxine sodium	0.9	1.4	5.1	1.9	-0.7	0.8	0.8	-1.7	0.6	2.3	-0.4	-2.0	1.0	1.7	-0.1	0.6	-0.8	-0.5	0.2
Had menopause	0.9	1.1	4.4	-0.4	-0.9	-0.3	-0.7	-1.7	-1.2	-0.1	-1.1	-2.1	-0.0	0.1	0.1	-0.2	-1.0	-2.1	-0.6
Number of live births	0.9	1.3	4.5	1.1	0.2	1.3	1.0	-1.8	1.1	1.5	0.1	-2.1	0.3	2.1	-0.6	0.1	0.5	0.1	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	4.9	-0.0	1.6	0.6	1.3	2.2	0.1	0.4	0.9	2.0	-0.3	0.5	-0.8	0.5	1.1	1.4	1.4
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	6.0	2.5	-0.4	1.3	1.3	-1.6	0.1	1.9	-0.5	-2.0	1.0	2.4	0.7	0.7	-0.8	-0.2	0.0
Chest pain or discomfort	0.9	1.3	4.2	-0.9	1.8	0.9	0.5	2.0	-0.6	0.4	1.5	2.0	0.1	0.8	-0.5	0.6	1.4	1.3	1.0
Medication: Aspirin	0.9	1.2	2.9	-1.7	-0.9	-1.5	-1.4	0.0	-0.7	-1.7	-1.2	-0.1	-1.3	-1.1	1.2	-0.5	-1.2	-0.9	0.2
Smoking status: Previous	0.9	1.4	2.6	-1.1	-1.3	-1.5	-1.4	-0.6	-1.6	-1.4	-1.5	0.2	-1.5	-1.1	0.2	-1.1	-0.7	-1.4	-0.8
Mineral and other dietary supplements	0.9	1.2	10.8	0.4	0.8	0.8	1.6	0.9	0.0	-0.3	1.1	-0.1	3.3	0.6	0.1	-0.1	0.2	1.3	0.5
Osteoporosis (self-reported)	0.9	1.1	3.4	-1.2	-0.4	-1.4	-1.2	0.1	-1.4	-1.9	-0.5	0.7	-1.1	-1.4	-0.1	-1.0	0.8	-0.3	-1.4
Osteoarthritis (self-reported)	0.9	1.2	4.8	-0.4	-1.2	-1.1	-1.4	-1.1	-2.2	-1.0	-1.2	-1.0	-1.2	-0.3	0.6	-0.4	-0.8	-1.4	-0.1
Ever taken oral contraceptive pill	0.9	1.0	3.1	1.0	1.0	1.5	0.9	-0.2	1.6	1.7	1.0	-0.1	-0.1	1.3	-0.7	0.6	0.9	1.0	0.4
Medication: Atorvastatin	0.9	1.1	2.5	1.6	1.0	1.4	1.3	-0.3	1.4	0.8	1.2	-0.5	0.9	1.2	-1.0	0.7	0.2	0.9	0.9
Arm fat-free mass (left)	0.9	4.3	14.3	-0.4	-2.5	-1.5	-0.6	-2.7	-3.8	-1.2	-2.0	-2.8	-1.0	-0.2	-2.1	0.4	-3.3	-2.9	-0.6
Age started oral contraceptive pill	0.9	1.1	3.5	-0.7	-0.7	-1.0	-1.0	-0.8	-1.6	-1.4	-1.2	-0.9	-0.2	-0.7	1.0	0.0	-1.9	-1.2	0.5
Chronotype (morning person)	0.8	1.8	5.1	-1.3	-1.5	-1.9	-1.4	0.1	-0.7	-2.3	-1.2	0.7	-0.6	-2.2	0.9	-0.6	-0.8	-1.4	-1.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	3.9	-1.0	-1.3	-0.9	-0.4	-0.4	0.1	0.2	-0.5	-0.5	-1.1	-1.2	-1.0	0.6	-2.0	-0.9	0.6
Angina	0.8	1.0	2.3	1.3	0.6	1.1	1.5	0.9	-0.0	0.2	1.2	0.3	1.5	0.9	-0.1	0.6	1.4	1.5	-0.2
Sitting height	0.8	5.8	18.6	1.9	-3.1	-0.9	-1.6	-4.3	-1.2	-1.1	-2.8	-3.3	-2.1	0.2	-0.9	-0.9	-2.2	-3.4	-3.7
Impedance of arm (right)	0.8	3.7	16.8	1.0	2.1	1.7	-0.1	1.7	3.5	0.8	1.5	2.3	1.3	1.1	-0.1	-0.2	4.1	2.5	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	3.5	-1.2	-0.8	-1.4	-0.2	0.8	-0.7	-1.1	-0.7	0.5	0.5	-1.9	0.8	-0.5	-1.6	-0.9	0.1
Arm fat-free mass (right)	0.8	4.3	16.6	-0.7	-2.5	-1.8	-0.9	-2.5	-4.1	-1.2	-2.0	-2.5	-1.8	-0.6	-1.5	0.2	-3.0	-2.9	-0.2
Arm predicted mass (right)	0.8	4.0	17.0	-0.6	-2.3	-1.7	-1.0	-2.5	-4.1	-1.3	-1.9	-2.4	-1.6	-0.5	-1.4	0.3	-2.9	-2.7	-0.1
Suffer from ‘nerves’	0.8	1.3	4.8	-2.2	-0.8	-1.8	-1.1	0.5	-0.2	-1.9	-0.9	0.8	-1.1	-1.9	0.7	-0.4	0.1	-0.7	0.3
Eye problems/disorders: Cataract	0.8	1.0	3.3	-0.3	1.2	0.5	1.5	1.8	0.1	1.1	0.9	1.6	-0.1	0.1	0.9	-1.0	0.8	0.9	0.8
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.0	-1.7	-0.8	-1.6	-0.6	0.3	-1.1	-0.8	-1.2	0.5	-1.1	-1.6	-0.8	-0.2	-0.8	-0.7	0.6
Medication: Bendroflumethiazide	0.8	1.2	7.1	-0.7	-0.0	-0.6	0.4	-0.6	-1.7	-1.2	-0.5	-0.9	2.7	-0.0	0.1	0.7	0.3	0.9	1.9
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	3.3	-1.8	-0.5	-1.4	-1.1	0.5	-1.6	-1.0	-1.1	0.5	-0.5	-1.1	1.6	-0.6	0.2	-0.7	0.5
Arm predicted mass (left)	0.8	4.2	12.8	-0.6	-2.5	-1.7	-0.7	-2.6	-3.6	-1.1	-2.0	-2.8	-1.1	-0.3	-2.1	0.6	-3.3	-2.9	-0.3
Verbal and Numeric Reasoning (VNR)	0.7	1.8	6.3	2.2	0.5	1.9	1.7	-0.2	2.5	1.9	-0.1	-0.7	0.5	1.9	-1.2	0.6	-0.4	-0.2	-0.8
Neuroticism	0.7	1.7	6.5	-0.4	1.6	1.1	0.3	0.8	0.4	0.5	1.2	1.1	-1.2	1.3	-2.5	1.9	1.6	1.1	1.2
Number of treatments/medications taken	0.7	1.2	3.8	-1.0	-0.9	-1.4	-1.7	-0.9	-2.0	-1.6	-1.4	-0.3	-1.1	-0.6	0.7	-0.5	-0.6	-1.0	0.0
Diabetes (mother)	0.7	0.9	3.1	-1.2	-1.0	-1.6	0.2	0.6	-0.2	0.1	-0.5	-0.0	0.9	-1.5	-0.1	-0.6	-1.7	-1.0	0.6
Pack years adult smoking proportion	0.7	1.1	2.7	1.3	1.0	0.2	1.3	1.6	-0.6	0.9	1.2	1.4	0.4	-0.5	0.3	-0.7	1.3	1.3	1.0
Average weekly fortified wine intake	0.7	0.8	2.6	0.2	-1.1	-0.6	-0.2	-0.2	0.8	0.9	-1.0	-0.6	0.3	-0.7	1.5	-1.0	-1.6	-1.0	0.7
Relative age voice broke	0.7	1.1	2.2	-1.0	-0.7	-1.2	-1.3	0.4	-0.5	-1.1	-1.1	0.6	-1.2	-1.0	0.6	-1.4	0.3	-1.4	-1.5
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	4.0	0.4	0.9	0.9	0.4	0.9	1.0	0.3	2.0	1.0	-0.1	0.2	-1.0	-0.6	1.1	0.7	-0.6
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.8	-1.2	-0.9	-1.1	-0.9	0.0	-0.1	-1.0	-0.9	0.1	-1.4	-1.2	0.9	-0.4	0.1	-0.4	-1.7
Alcohol usually taken with meals	0.7	1.1	4.0	-0.1	-0.8	-1.1	-1.7	-0.4	-0.7	0.1	-1.0	0.2	-2.0	-1.4	0.7	-0.9	-0.8	-1.9	-0.0
Diabetes (self-reported)	0.7	1.0	3.6	0.4	0.7	0.9	1.9	0.4	0.5	1.9	1.2	-0.4	0.3	0.6	-1.7	-0.0	-0.4	0.3	1.3
Neuroticism score	0.7	1.4	5.6	-1.0	1.2	0.6	0.1	0.9	0.3	0.0	0.7	1.1	-1.2	1.1	-2.4	1.8	1.6	1.2	1.1
Hair/balding pattern: Pattern 3	0.7	1.0	3.4	0.6	1.0	0.8	0.2	0.6	0.3	1.6	0.5	0.8	-1.5	0.8	1.3	1.2	-0.1	0.1	1.8
Pulse rate	0.7	1.2	5.7	-2.4	-1.0	-1.5	-1.2	-0.1	-1.3	-0.4	-1.0	-0.3	0.3	-1.2	0.6	-0.2	-1.5	-1.4	0.5
Blood clot in the leg (DVT)	0.7	0.9	3.3	-1.8	-0.1	-1.2	-0.9	0.8	-1.4	-0.8	-0.8	0.8	-0.2	-1.0	1.6	-0.5	0.6	-0.4	0.6
Pulse wave peak to peak time	0.7	0.8	2.8	0.7	-0.2	0.8	0.3	-0.8	1.7	1.3	0.3	-0.8	-0.7	1.0	-0.7	-1.3	0.3	-0.7	-1.2
Emphysema/chronic bronchitis	0.7	0.8	4.7	0.5	0.0	0.2	0.6	-0.8	-0.9	0.1	-0.0	-0.5	-0.3	0.7	-2.2	-0.1	2.0	0.9	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	3.3	0.9	1.2	0.9	0.8	1.1	1.8	0.9	1.1	0.5	-0.3	0.4	0.7	-0.4	0.8	1.2	0.8
Leg pain on walking	0.7	0.9	2.8	-1.1	-0.6	-1.3	-0.2	0.6	-1.1	0.3	-0.1	0.3	-1.5	-1.7	0.3	-1.6	-0.9	-1.1	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.5	-1.5	-0.8	-1.1	-0.6	0.2	-0.0	-1.5	-0.3	0.1	-0.3	-1.3	0.3	-0.3	-1.9	-0.9	0.4
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.5	1.3	1.0	1.3	0.8	-0.4	-0.1	0.2	1.0	-0.2	-0.1	1.3	-0.9	0.3	1.6	1.2	0.3
Miserableness	0.7	1.2	3.6	-0.1	1.3	0.8	0.7	1.2	-0.1	0.3	0.7	1.2	-0.5	1.1	-1.6	1.7	1.1	1.9	1.3
Commuting to job workplace: Public transport	0.7	0.8	2.5	0.4	-1.0	-0.8	-0.5	-1.6	1.2	-0.5	-1.4	-1.2	0.6	-0.6	0.2	-0.6	-0.3	-0.8	-1.4
High cholesterol (Self-reported)	0.7	1.2	5.3	2.3	1.1	1.2	1.6	0.9	-0.0	1.1	0.9	0.6	0.5	1.2	-0.6	0.5	0.7	1.1	0.6
Diastolic blood pressure, automated reading	0.7	2.3	9.0	-2.9	-0.3	-1.5	-1.5	-0.2	-3.0	-1.2	-1.5	0.7	-0.2	-0.6	-1.3	2.3	-0.4	-0.6	1.5
Myopia	0.7	1.0	5.5	1.0	1.0	0.9	0.5	0.6	-0.3	-1.1	0.9	0.4	2.3	0.9	-0.4	1.6	0.8	1.1	-0.0
Neuroticism (Nagel 2018)	0.6	1.4	5.5	-1.7	0.5	-0.2	-1.0	0.7	-0.6	-0.2	-0.3	0.8	-2.3	0.5	-2.0	2.4	0.9	0.5	1.0
Worry (Nagel 2018)	0.6	1.2	11.9	-1.4	-0.1	-0.7	-1.1	0.4	0.1	-1.0	-0.4	0.7	-3.5	-0.5	-0.5	1.1	0.4	-0.0	-0.2
Rheumatoid Arthritis	0.6	0.8	6.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.0	-2.3	-2.6
Blood Platelet Count	0.6	6.8	20.4	-4.5	-0.3	-3.1	-2.7	2.5	-3.1	-3.5	-0.2	2.9	-2.4	-4.5	-1.7	1.0	-0.6	0.3	2.1
Height	0.6	10.6	37.8	3.9	-3.3	0.6	-1.4	-5.5	-1.4	0.3	-2.4	-5.1	-1.5	1.9	-3.3	-2.3	-0.7	-4.3	-6.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.1	-0.1	0.5	0.0	-0.1	0.8	-0.9	1.4	-0.7	1.3	-1.4	0.8	1.1	0.9	1.0	0.5	0.1
Supplements: Zinc	0.6	0.6	1.8	0.8	-0.5	0.2	-0.7	-1.3	1.1	-0.8	-0.0	-1.0	0.2	-0.0	0.3	-0.7	-1.0	-1.1	-1.1
Medication: Metformin	0.6	0.9	3.1	0.8	-0.5	0.4	1.3	-1.1	0.8	1.2	0.2	-1.7	0.5	0.4	-1.8	-0.5	-1.0	-0.5	-0.1
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	1.1	0.8	1.4	0.8	0.6	-0.4	1.5	1.2	0.4	-0.1	1.2	-0.9	0.3	0.3	0.4	-0.4
High blood pressure (mother)	0.6	0.9	2.6	-0.9	-1.1	-0.9	-1.6	-0.8	-0.1	-1.5	-0.7	-0.4	-1.3	-0.9	-0.1	0.6	-1.1	-1.1	0.5
Past tobacco smoking	0.6	1.1	3.2	1.0	0.9	1.3	1.1	-0.2	1.8	0.8	1.2	-0.8	1.7	0.9	-1.1	1.0	-0.1	0.9	0.2
Trunk fat-free mass	0.6	3.5	12.2	0.0	-2.5	-1.4	-0.6	-2.7	-3.5	-1.3	-1.9	-2.4	-0.7	-0.2	-1.8	0.3	-2.5	-2.4	-0.7
Worrier / anxious feelings	0.6	1.1	8.0	-0.6	0.6	0.4	-0.6	0.3	1.3	0.5	0.4	0.6	-2.8	0.6	-0.9	1.9	0.4	0.5	0.3
Prospective memory result	0.6	0.8	2.6	-1.2	-0.3	-0.9	-0.3	0.7	0.6	-0.9	0.3	0.8	1.0	-1.4	1.6	-0.4	-0.8	0.4	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	4.3	0.1	-1.9	-1.1	-0.5	-1.6	-0.6	-2.1	-1.5	-1.8	-1.6	-1.1	0.0	-0.7	-1.6	-1.6	-1.5
Pulse wave Arterial Stiffness index	0.6	0.7	3.0	-0.6	0.1	-0.7	-0.3	0.6	-1.7	-1.2	-0.4	0.6	0.9	-0.8	0.6	1.4	-0.4	0.6	1.0
Trunk predicted mass	0.6	3.5	11.8	0.1	-2.5	-1.4	-0.6	-2.7	-3.4	-1.2	-1.9	-2.5	-0.6	-0.1	-1.8	0.3	-2.6	-2.5	-0.8
Medication: Ventolin 100micrograms inhaler	0.6	0.8	4.6	-0.3	-0.1	-0.9	0.1	0.1	-2.0	-1.0	-0.3	0.4	0.3	-0.4	-0.3	0.1	2.1	1.0	0.8
Birth weight	0.6	1.4	4.0	1.6	1.3	1.3	-0.4	0.6	-0.2	0.6	1.3	1.0	-2.0	1.0	-2.0	1.7	0.5	0.7	0.0
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.5	-0.6	0.2	-0.8	-0.3	0.1	-1.3	-0.5	-0.9	0.6	-1.1	0.4	-1.1	1.1	1.6	0.9	0.0
Forced vital capacity (FVC), Best measure	0.6	2.1	7.4	-0.2	-1.7	-1.3	-1.0	-1.4	-1.2	-1.8	-1.6	-1.3	-2.7	-1.2	-0.2	-0.6	-1.3	-1.9	-1.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.5	-0.9	0.6	0.3	0.2	0.8	-1.1	-0.6	0.3	1.1	1.2	0.6	-1.1	0.9	1.0	1.0	1.2
Medication for pain relief, constipation, heartburn	0.6	1.0	3.5	1.8	-0.4	0.6	1.9	-0.1	1.4	1.3	0.1	-0.8	1.5	0.1	0.6	-1.3	-0.1	0.2	-0.7
Neck or shoulder pain in last month	0.6	0.9	1.9	-0.5	1.3	0.4	0.9	1.3	-0.4	0.4	1.3	1.0	-0.9	0.7	-1.4	0.4	1.3	0.8	0.9
Angina (self-reported)	0.6	0.7	2.1	1.2	0.4	1.0	1.4	0.8	-0.0	0.0	0.8	0.1	1.4	0.9	0.1	0.6	1.0	1.3	-0.3
Medication: Allopurinol	0.6	0.8	4.8	-0.6	-0.5	0.0	0.5	-0.8	0.2	1.2	-0.1	-0.9	-2.2	0.3	-1.1	-0.9	0.2	-1.0	-1.3
Pulse rate, automated reading	0.6	2.0	5.6	-2.3	-1.3	-1.7	-2.4	-0.8	-1.6	-0.4	-1.4	-0.4	0.3	-1.1	-0.4	0.2	-2.2	-2.2	0.5
Family relationship satisfaction	0.6	0.7	2.0	-0.2	0.9	0.4	1.2	1.3	-0.9	-0.8	1.1	0.8	1.4	0.5	0.1	-0.4	0.8	0.7	0.7
Ever had bowel cancer screening	0.6	0.8	3.0	-0.1	0.5	0.3	0.8	1.7	0.9	-0.5	0.5	1.4	0.6	-0.5	1.7	-0.8	0.0	0.8	0.0
Number of self-reported non-cancer illnesses	0.6	1.0	3.2	-0.9	1.1	-0.3	-0.0	1.3	-1.6	-0.7	0.2	1.5	0.3	0.3	-0.7	0.2	1.8	1.3	1.0
Financial situation satisfaction	0.6	0.8	3.0	0.1	0.8	0.5	1.0	0.8	-0.6	0.1	0.9	1.0	0.5	0.6	0.1	-1.5	1.7	1.2	0.0
Number of operations (self-reported)	0.6	0.8	4.4	-0.6	-0.8	-0.8	-0.4	-0.8	-1.1	-0.3	-1.0	-0.5	2.1	-0.0	0.2	-1.3	1.2	-0.3	-0.6
Ever depressed for a whole week	0.6	0.7	1.9	-0.9	-1.3	-1.4	-0.3	-0.1	-0.6	-1.1	-1.4	-0.3	-0.8	-0.9	-0.2	0.4	-1.1	-0.5	0.3
Pain experienced in last month	0.6	1.0	5.0	0.9	-0.8	0.1	-0.0	-0.8	0.4	-0.4	-0.8	-1.0	0.6	-0.3	2.2	-1.2	-0.6	-0.8	-1.8
Pack years of smoking	0.6	0.9	2.4	1.2	0.7	-0.1	1.2	1.6	-0.9	0.9	0.9	1.2	0.0	-0.7	0.5	-1.0	0.9	0.8	0.8
Impedance of whole body	0.6	3.2	15.2	1.4	1.9	2.0	0.2	1.2	3.9	2.0	1.6	1.2	0.9	1.7	1.0	-0.8	2.9	1.3	-1.4
Mean Putamen Volume	0.5	0.6	2.2	0.2	1.3	0.5	0.5	1.5	0.2	0.4	1.2	1.5	-0.4	-0.3	0.5	-0.3	0.0	-0.0	0.7
HbA1C	0.5	0.6	1.6	1.2	-0.1	0.2	1.3	-0.5	-1.1	-1.3	-0.1	-0.6	1.3	-0.3	0.3	-0.9	0.4	0.3	-0.4
Lung FEV1/FVC ratio	0.5	2.5	11.4	1.6	-1.0	0.5	1.5	-1.4	0.2	-1.6	0.1	-2.5	2.1	0.3	0.8	-1.7	-3.4	-1.1	-1.5
Severe depression (siblings)	0.5	0.5	3.1	0.6	0.8	0.5	-0.0	-0.1	0.6	-0.4	1.3	-0.1	-0.3	0.5	-1.8	-0.6	0.9	0.2	-0.5
Hand grip strength (right)	0.5	1.4	5.8	2.0	0.0	0.8	-0.0	-1.5	-0.2	-0.2	0.2	-1.3	-2.4	0.9	-1.6	1.7	-0.3	-0.3	-1.0
Impedance of leg (left)	0.5	2.2	11.1	1.5	0.9	1.5	0.3	-0.2	3.3	2.4	1.1	-0.6	0.7	1.6	1.8	-1.3	0.4	-0.6	-1.9
Waist circumference	0.5	1.7	12.7	-1.4	-0.9	-1.9	-0.6	0.1	-3.6	-1.4	-0.9	0.2	0.1	-1.2	-0.8	-0.6	-0.7	-0.8	1.1
Hearing difficulty/problems with background noise	0.5	0.8	1.9	0.2	1.4	0.8	0.3	1.0	-0.4	-0.3	1.3	1.0	-0.0	0.8	-1.3	1.0	1.1	1.0	0.8
Heart attack	0.5	0.6	2.4	0.5	0.7	0.5	1.6	1.4	0.6	1.1	1.2	0.9	-0.3	0.6	-0.2	0.0	0.5	0.4	-0.3
Time employed in main current job	0.5	0.6	1.9	0.3	-0.4	-0.0	-0.2	-1.0	-0.1	-0.7	-0.3	-1.2	0.0	0.0	0.4	-1.3	-1.4	-1.1	-0.5
Noisy workplace	0.5	0.6	1.9	0.7	0.6	0.6	1.2	0.4	-0.3	-0.9	1.4	-0.2	1.0	-0.0	-1.2	-1.0	0.5	0.6	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.2	-1.4	0.4	-0.3	-1.5	0.4	-0.5	-0.4	0.6	1.0	-0.8	-0.6	-1.1	0.4	-0.4	-0.6	0.7
Illnesses of mother	0.5	0.6	2.5	0.0	0.6	0.4	0.2	1.3	0.5	1.2	0.5	1.0	-0.1	0.0	-0.0	-1.1	0.6	0.0	-1.6
Breastfed as a baby	0.5	0.7	6.5	-0.0	-0.1	-0.3	0.7	0.8	0.4	-0.2	-0.3	-0.1	-0.1	-0.8	2.6	-0.8	-1.0	-0.5	-0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.2	-0.3	0.7	-0.1	0.3	1.1	-0.6	1.2	0.3	1.5	0.5	0.5	-0.7	0.3	0.7	0.6	1.5
Medication: Ibuprofen	0.5	0.6	2.2	-1.5	0.3	-0.6	-1.3	0.5	-1.0	-0.1	0.4	0.8	-0.4	-0.7	-0.3	0.7	-0.8	-0.7	1.2
Medication: Omeprazole	0.5	0.6	1.9	1.4	0.1	0.8	0.7	-0.6	-1.3	1.1	0.5	-0.5	-1.1	0.8	-0.0	0.5	-0.3	0.0	0.4
Medication: Seretide 50 evohaler	0.5	0.5	2.0	-0.2	0.2	-0.3	-0.3	-0.0	-1.4	-0.9	0.4	0.4	0.4	-0.4	1.0	-1.0	0.9	0.6	1.3
Mean time to correctly identify matches	0.5	0.9	2.7	-1.4	-1.4	-1.3	-0.5	0.1	-1.1	-1.5	-0.9	-0.2	0.7	-1.6	0.9	-0.4	-0.7	-0.5	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.2	0.5	-0.2	-0.1	-0.9	-1.1	-1.0	-1.2	-0.4	0.3	-1.5	-0.2	-1.0	0.7	0.6	0.3	0.9
Illnesses of father: Heart disease	0.5	0.7	1.8	0.8	0.2	0.5	1.0	-0.2	-0.8	-0.4	-0.3	-0.4	1.2	1.0	-0.7	0.8	1.3	1.2	0.8
Whole body fat-free mass	0.5	3.1	14.3	-0.4	-2.1	-1.4	-0.7	-2.1	-3.8	-1.6	-1.8	-1.9	-0.8	-0.4	-2.2	0.6	-2.0	-1.9	-0.3
Mood swings	0.5	1.0	7.5	-0.7	0.5	-0.0	-0.0	0.1	-1.0	-0.4	-0.3	0.0	-0.2	0.9	-2.7	1.6	1.0	0.6	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.9	0.5	0.5	0.5	1.3	-0.3	0.4	0.5	0.5	-0.4	1.0	0.7	-0.4	-1.0	1.4	0.7	-0.3
Medication: Aspirin	0.5	0.7	2.0	-1.4	-0.6	-1.1	-1.0	0.0	-0.2	-1.2	-0.9	-0.2	-0.8	-0.6	1.3	-0.6	-0.7	-0.7	0.2
Whole body water mass	0.5	3.1	14.4	-0.3	-2.2	-1.5	-0.7	-2.1	-3.8	-1.7	-1.8	-1.8	-1.0	-0.4	-2.2	0.6	-2.1	-1.9	-0.3
Average weekly champagne plus white wine intake	0.5	0.7	4.5	0.7	0.1	0.0	-0.5	0.3	0.5	-0.9	-0.5	0.4	0.7	-0.4	1.0	-2.1	0.2	-0.8	-1.4
Wears glasses or contact lenses	0.5	0.6	1.3	-0.4	-1.0	-0.7	-0.8	-0.4	0.2	-1.2	-0.9	-0.8	-0.1	-0.6	-0.8	-0.7	-0.6	-0.9	-1.1
Mother’s age at death	0.5	0.6	2.6	-0.0	0.4	0.3	0.4	-0.0	0.1	0.2	-0.1	-0.3	-0.7	0.6	-1.6	1.5	-1.3	0.0	1.5
Eye problems/disorders: Glaucoma	0.5	0.5	2.7	1.3	0.1	0.3	1.1	0.1	0.1	1.6	0.5	-0.7	0.4	0.3	0.5	-1.0	-0.7	-0.2	0.5
Basal metabolic rate	0.5	2.6	14.6	-0.4	-1.8	-1.3	-0.7	-1.8	-3.8	-1.6	-1.5	-1.4	-0.7	-0.3	-2.4	0.7	-1.5	-1.5	0.0
Risk taking	0.5	0.7	5.5	-0.8	-0.5	-1.0	-0.5	0.2	-2.3	-0.9	-1.0	-0.1	-0.4	-0.9	-0.3	-0.2	-0.9	-0.3	0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.5	2.1	1.4	0.3	0.8	0.5	-0.3	-1.2	0.7	0.5	-0.0	-1.4	0.9	-0.7	0.5	0.4	0.2	0.1
Depressed Affect (Nagel 2018)	0.4	0.9	5.1	-0.6	0.5	0.2	-0.2	0.2	-0.7	0.3	-0.1	0.3	-0.7	0.9	-2.2	2.1	1.0	0.6	1.2
LDL Cholesterol	0.4	0.7	6.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	2.5	1.6
BMI	0.4	2.6	15.4	-2.3	-0.7	-2.0	-0.2	1.0	-3.9	-1.7	-0.8	1.0	0.3	-1.3	-1.0	0.7	-0.8	-0.0	2.6
Lung FVC	0.4	2.1	5.9	-0.5	-1.6	-1.6	-0.3	-1.2	-1.9	-2.4	-2.0	-1.2	-1.2	-2.1	0.6	-1.5	-1.2	-1.5	0.3
Tanning	0.4	5.0	13.6	0.9	2.8	1.5	2.4	2.8	-0.1	0.9	2.3	3.0	3.2	1.3	0.9	0.7	2.9	3.7	2.4
Vitamin and mineral supplements	0.4	0.6	3.1	-0.0	0.2	-0.0	1.4	1.1	0.7	0.4	0.4	0.3	1.8	-0.3	1.0	-0.7	0.1	0.5	-0.2
Impedance of leg (right)	0.4	1.7	7.1	1.0	1.0	1.1	0.1	0.2	2.7	2.3	1.1	-0.0	1.2	1.0	1.8	-1.7	0.5	-0.8	-1.4
Leg fat-free mass (left)	0.4	2.2	15.4	-0.8	-1.1	-1.2	-0.8	-0.6	-3.9	-1.9	-1.1	-0.1	-0.7	-0.6	-2.8	0.9	-0.2	-0.3	0.7
Fed-up feelings	0.4	0.7	4.0	0.4	1.0	1.0	0.3	0.1	0.3	0.3	1.0	0.3	1.0	1.0	-2.0	0.3	1.1	0.8	0.4
Body mass index (BMI)	0.4	1.7	9.5	-1.6	-0.3	-1.3	-0.3	0.4	-3.1	-1.1	-0.3	0.5	-0.0	-0.9	-1.9	0.8	-0.5	-0.0	2.3
Leg predicted mass (left)	0.4	2.2	15.3	-0.9	-1.0	-1.2	-0.7	-0.6	-3.9	-1.9	-1.1	-0.0	-0.7	-0.6	-2.8	1.1	-0.2	-0.3	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.7	-0.9	0.7	0.0	-0.8	0.9	-0.5	-1.0	0.2	1.5	-0.2	0.2	-0.9	0.3	1.6	0.8	-0.1
Had other major operations	0.4	0.4	1.5	-0.7	-0.5	-0.9	-1.2	0.1	0.1	-0.8	-0.4	0.4	0.1	-0.3	-0.8	-0.2	1.0	-0.2	-1.1
Financial difficulties in last 2 years	0.4	0.5	1.8	-0.7	-0.1	-0.3	0.9	0.8	-1.2	-0.1	0.3	0.2	1.3	-0.7	-0.2	-1.1	-0.6	-0.3	0.3
Medication: Simvastatin	0.4	0.6	3.6	1.4	0.3	0.8	1.9	0.6	-0.2	0.3	0.7	-0.1	0.4	0.6	-0.1	0.6	-0.5	1.1	0.7
Arm fat percentage (right)	0.4	1.4	4.7	-1.4	0.1	-1.0	-0.4	1.0	-2.2	-1.2	-0.2	1.5	0.7	-0.7	-2.1	0.4	1.2	0.8	1.4
Hip circumference	0.4	1.9	13.7	-1.4	-1.0	-1.6	-0.7	-0.5	-3.7	-1.5	-1.1	-0.2	0.5	-0.6	-2.1	0.5	-0.1	-0.7	1.4
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.6	0.1	0.9	0.7	1.0	1.4	1.3	0.9	0.4	0.9	-1.3	1.0	-0.3	0.3	1.6	1.3	0.8
Lung cancer (father)	0.4	0.4	1.4	-0.7	0.4	-0.1	-0.1	0.8	-0.7	-0.5	0.5	1.2	0.3	-0.7	1.0	-0.3	-0.9	-0.6	0.3
Hair/balding pattern: Pattern 4	0.4	1.0	5.7	-0.2	-0.7	-0.6	0.4	-1.2	-0.8	-0.6	-0.3	-2.1	0.4	-0.0	-0.5	0.2	-2.4	-1.2	0.7
Loud music exposure frequency	0.4	0.4	2.1	0.0	-0.0	0.1	-0.0	-0.2	-1.2	-0.5	0.1	0.0	0.5	0.4	-0.5	-0.3	1.3	0.1	-1.4
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.8	-0.4	0.5	-0.5	-0.0	1.0	-1.7	-0.2	0.6	1.2	-0.9	-0.7	0.1	0.3	0.3	-0.1	0.7
Number of full brothers	0.4	0.5	3.3	0.9	0.0	0.2	1.0	-0.5	0.7	0.5	0.4	-0.9	1.0	0.5	-0.3	-1.8	0.3	-0.1	-0.4
Age at first live birth	0.4	0.8	3.3	-0.9	-0.6	-1.0	0.1	1.0	0.9	-0.3	-0.3	0.1	0.9	-1.8	1.3	-0.6	-1.2	-0.6	0.3
Qualifications: College or University degree	0.4	1.1	6.8	1.2	1.0	1.0	-0.3	0.2	2.2	0.6	0.4	0.5	-2.6	1.1	-0.3	0.9	0.4	0.0	0.2
Migraine (self-reported)	0.4	0.5	2.8	-0.5	0.4	0.0	0.3	0.9	-0.6	-0.5	0.4	0.8	0.7	-0.0	-1.7	0.8	-0.3	0.8	1.2
Leg fat mass (right)	0.4	1.6	11.0	-1.2	-0.3	-1.2	-0.7	0.3	-3.3	-0.7	-0.3	0.5	0.0	-0.7	-2.4	0.3	-0.6	-0.7	1.6
Comparative height size at age 10	0.4	2.1	6.7	2.6	0.0	1.8	0.4	-2.0	-0.8	0.9	0.1	-2.0	1.1	2.6	-1.9	0.5	0.4	-0.2	-1.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.4	0.3	-0.4	-0.2	-1.2	-0.9	0.7	-0.7	-0.3	-0.4	-0.8	0.0	-0.8	0.8	0.5	-0.1	-1.2
Knee pain experienced in last month	0.4	0.6	1.8	0.6	0.4	0.2	0.5	0.6	-0.6	-0.3	0.1	0.6	1.3	0.9	-1.0	0.8	1.0	1.2	0.7
Leg fat-free mass (right)	0.4	2.0	12.9	-0.6	-1.1	-1.0	-0.7	-0.9	-3.6	-2.0	-1.2	-0.4	-1.0	-0.4	-2.7	1.1	-0.4	-0.2	0.4
Arm fat percentage (left)	0.4	1.8	6.0	-1.6	0.4	-1.0	-0.5	1.4	-2.4	-1.2	0.0	2.0	0.5	-0.7	-1.8	0.4	1.6	1.0	1.7
Long-standing illness, disability or infirmity	0.4	0.6	2.6	-0.9	-0.3	-0.9	0.1	0.3	-0.9	1.6	-0.8	0.1	-0.0	0.2	1.4	-0.4	-0.3	-0.3	1.1
Leg predicted mass (right)	0.4	2.0	12.9	-0.6	-1.1	-1.0	-0.7	-0.9	-3.6	-2.0	-1.2	-0.4	-1.0	-0.3	-2.7	1.2	-0.4	-0.3	0.4
Arm fat mass (left)	0.4	1.5	9.7	-1.4	-0.3	-1.2	-0.8	0.4	-3.1	-1.4	-0.5	0.8	-0.1	-0.5	-2.2	0.8	0.4	-0.0	1.3
Medication: Blood pressure	0.4	0.8	3.9	-0.6	0.7	-0.3	0.4	1.1	-1.5	-1.1	0.4	0.8	0.9	-0.3	0.4	0.1	0.4	0.9	2.0
Medication: Lisinopril	0.4	0.6	2.0	0.9	0.4	0.5	1.4	0.4	-0.0	0.3	0.5	0.1	0.8	1.1	-0.8	-1.3	0.6	0.1	-0.9
Irritability	0.4	0.6	2.7	-0.3	0.1	0.3	-0.8	-0.5	0.3	0.6	-0.3	-0.5	-1.1	1.2	-1.6	1.5	-0.5	-0.6	0.0
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.6	0.0	-0.7	-0.2	-0.4	-0.3	-0.2	1.0	-0.6	-0.6	-0.0	-0.5	-0.3	-0.5	-1.6	-1.1	-0.6
Leg fat mass (left)	0.4	1.5	10.6	-1.1	-0.5	-1.1	-0.6	-0.0	-3.2	-0.9	-0.5	0.2	-0.1	-0.5	-2.4	0.4	-0.7	-0.7	1.3
Depression (Nagel 2018)	0.3	0.5	3.5	-0.0	0.9	0.5	-0.3	0.5	0.2	0.5	0.6	0.9	-0.1	0.8	-0.6	-0.1	1.9	0.6	0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.5	1.4	0.5	1.4	1.0	-0.1	1.8	0.8	-0.1	-0.7	0.3	1.9	-0.9	0.8	-0.3	0.2	-0.2
Ovarian Cancer	0.3	0.4	1.3	-0.8	-0.7	-0.7	-1.1	-0.0	-0.6	0.3	-0.6	0.3	0.6	-0.9	0.0	-0.7	-0.2	-1.1	-0.8
Fasting Glucose	0.3	0.4	1.3	0.4	0.7	0.1	0.1	0.7	-0.5	-0.9	0.2	0.8	1.2	-0.3	0.8	-0.4	0.9	0.6	0.1
Neuroticism (2016)	0.3	0.4	1.6	-0.7	0.2	-0.4	-0.4	0.4	-0.9	-0.3	-0.3	0.8	-0.1	0.0	-1.1	1.3	-0.1	0.0	0.9
Primary Biliary Cirrhosis	0.3	0.4	1.7	0.1	0.6	0.9	0.8	0.8	0.5	1.3	1.0	0.1	0.0	0.5	-0.7	-0.4	-0.3	0.0	-0.4
Waist Hip Ratio (WHR)	0.3	1.4	8.2	-0.4	-0.7	-1.0	-0.4	0.1	0.6	-0.3	-0.5	0.1	-0.5	-1.3	2.6	-2.9	-0.7	-1.1	-1.1
Smoking Status	0.3	0.8	4.1	-1.1	0.2	-0.6	-0.4	0.8	-1.2	-0.5	-0.7	1.1	-0.1	-0.2	2.0	-0.7	1.1	0.6	0.9
Hand grip strength (left)	0.3	0.9	7.2	1.2	0.1	0.3	-0.1	-0.8	-0.5	0.1	0.4	-0.4	-2.7	0.1	-1.4	1.3	-0.2	-0.1	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	3.1	-0.4	0.6	0.0	-0.5	0.3	-0.1	-0.4	0.1	0.9	-0.6	0.6	-0.8	-0.3	1.8	0.9	0.1
High blood pressure	0.3	0.8	4.3	-1.3	0.3	-0.6	-0.6	0.4	-2.1	-1.7	0.0	0.7	0.8	-0.2	0.5	0.5	-0.0	0.4	1.1
Multivitamins +/- minerals	0.3	0.4	1.2	-0.9	-0.0	-0.5	-1.1	-0.4	-0.8	-0.9	-0.5	0.4	-0.6	-0.1	-0.9	1.1	0.4	0.2	0.5
Stomach or abdominal pain in last month	0.3	0.4	1.6	-0.8	0.1	-0.4	-0.2	0.5	-0.1	1.2	0.0	0.5	0.4	-0.5	1.1	-0.4	0.8	0.1	0.8
Number of incorrect matches in round	0.3	0.6	1.3	-0.3	-1.0	-0.9	-0.5	-0.7	-0.9	-0.4	-1.0	-0.8	0.0	-0.9	1.1	0.0	-0.9	-0.8	0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.4	0.6	0.5	0.2	1.1	0.6	0.6	0.2	0.6	0.2	-0.2	0.1	-0.6	-1.2	0.7	0.5	-0.6
Medication: Ramipril	0.3	0.4	1.8	-0.5	-0.0	-0.3	-0.3	-0.2	-0.4	-1.3	0.1	-0.3	-0.5	0.2	0.7	0.8	-1.2	0.4	1.1
Fluid intelligence score	0.3	0.7	2.8	1.3	0.1	0.9	0.6	-0.2	1.1	0.8	-0.9	-0.4	-0.7	1.2	-0.4	0.2	-0.2	-0.7	-1.7
Weight	0.3	1.7	12.8	-0.6	-0.8	-1.0	-0.4	-0.6	-3.6	-1.2	-0.7	-0.4	-0.1	-0.2	-2.7	0.6	-0.4	-0.6	0.9
Falls in the last year	0.3	0.3	1.3	-0.6	0.3	-0.2	-0.3	0.8	-0.6	-0.6	0.2	1.1	-1.2	-0.5	0.1	-0.5	0.6	-0.3	-0.0
Arm fat mass (right)	0.3	1.3	8.2	-1.1	-0.1	-0.9	-0.4	0.4	-2.9	-1.2	-0.2	0.8	0.3	-0.2	-2.5	0.8	0.5	0.2	1.2
Standing height	0.3	2.6	10.6	2.4	-1.1	0.8	-0.3	-2.6	-0.9	-0.3	-0.8	-2.2	-0.2	1.9	-2.2	-0.3	0.4	-1.3	-3.3
Pulse wave reflection index	0.3	0.4	2.2	-0.1	-0.3	-0.5	-0.4	-0.5	-0.8	-1.1	-0.4	-0.1	0.2	-0.6	-1.1	1.5	0.0	-0.0	0.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.4	0.1	0.8	0.4	1.1	1.1	0.5	0.5	0.2	0.8	0.5	0.8	-0.3	-0.6	1.2	1.0	0.4
Medication: Paracetamol	0.3	0.5	2.6	-1.3	0.2	-0.5	-1.6	0.1	-0.8	-0.8	-0.3	0.7	-0.7	-0.1	0.5	0.5	0.1	-0.6	-0.0
Leg fat percentage (right)	0.3	1.2	7.3	-1.3	-0.2	-1.2	-0.5	0.5	-2.7	-0.2	-0.0	0.6	0.5	-1.0	-1.5	-0.6	-0.4	-0.8	1.8
Whole body fat mass	0.3	1.2	8.8	-0.8	-0.2	-0.8	-0.4	0.2	-3.0	-1.0	-0.3	0.4	0.3	-0.2	-2.3	0.2	0.1	-0.2	1.1
Alcohol intake frequency.	0.3	0.7	3.6	0.3	-0.7	-0.4	-0.3	-1.3	0.2	-0.6	0.0	-1.0	1.8	-0.1	-1.9	0.1	0.4	-0.2	-1.0
Number of full sisters	0.3	0.4	1.3	0.8	-0.3	-0.2	0.5	-0.8	0.1	0.4	0.2	-1.0	0.9	-0.4	0.6	-1.1	-0.7	-0.7	-0.2
Age at last live birth	0.3	0.4	1.1	0.1	0.7	0.2	0.7	1.1	0.9	-0.0	0.7	0.5	1.0	-0.2	0.5	-0.5	0.8	0.6	0.4
Hypertension (Self-reported)	0.3	1.0	3.7	-1.0	0.9	-0.2	-0.0	0.8	-1.9	-1.0	0.5	1.0	1.0	0.2	0.3	1.0	0.1	1.0	1.9
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.3	-0.7	-0.3	-0.1	-1.3	-0.4	0.6	-0.4	-0.4	0.3	-1.0	0.5	-1.5	0.7	0.3	-0.7	-1.0
Diabetes diagnosed by doctor	0.3	0.4	2.0	-0.2	-0.0	0.1	1.4	-0.2	-0.1	1.0	0.4	-0.8	0.4	0.3	-1.1	-0.3	-0.7	0.0	1.0
Friendships satisfaction	0.3	0.3	2.3	-0.2	-0.2	-0.3	0.3	0.1	-0.1	0.4	0.1	-0.6	1.2	-0.4	0.2	-1.5	-0.2	-0.7	-0.1
Commuting to job workplace: Walk	0.3	0.3	1.0	0.7	0.4	0.6	0.3	0.3	-0.0	0.4	0.5	0.0	-0.5	0.9	-0.9	0.2	0.3	-0.5	-1.0
Breast cancer (self-reported)	0.3	0.3	1.3	-0.1	0.2	-0.4	0.3	1.1	-0.3	0.1	0.1	0.6	-0.8	-0.4	-0.3	1.1	-0.1	0.5	1.0
Medication: Gliclazide	0.3	0.4	2.2	-0.6	-0.2	-0.2	1.1	0.1	-0.7	-0.2	0.1	-0.3	0.9	-0.3	-0.4	-0.3	0.1	0.6	1.5
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	-0.6	0.4	0.1	0.2	1.2	0.6	0.3	0.9	0.8	-0.6	-0.6	0.3	-1.1	-0.4	-0.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.7	-0.5	-0.6	-0.7	-0.1	0.4	-0.2	-0.6	-0.4	0.1	-1.4	-1.0	1.1	-0.5	-1.6	-1.6	-0.1
Guilty feelings	0.3	0.5	1.2	-0.6	0.8	0.4	-0.6	1.0	0.5	-0.5	0.5	1.0	-0.6	0.2	-1.1	0.9	0.9	0.6	-0.2
Medication: Paracetamol	0.3	0.5	1.5	-1.2	0.5	-0.4	-1.0	0.2	-1.2	-0.4	-0.3	0.7	-0.5	0.4	0.7	1.0	-0.0	-0.3	0.6
Alcohol drinker status: Never	0.3	0.3	1.5	0.1	0.4	-0.1	-0.0	0.8	0.7	-0.4	0.7	0.7	1.2	-0.3	-0.0	0.2	0.8	0.5	-0.5
Ever smoked	0.3	0.5	2.0	-0.2	-0.6	-0.8	-0.8	0.0	-1.2	-0.4	-1.2	0.6	-1.4	-0.0	0.8	-0.5	0.5	-0.4	0.0
Fractured/broken bones in last 5 years	0.3	0.4	1.4	-0.9	-0.3	-0.6	-1.1	-0.2	-0.6	-1.2	-0.7	0.2	0.3	-0.4	0.7	-0.4	0.6	-0.0	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.1	0.3	0.5	0.4	1.4	1.3	0.4	0.8	1.0	0.8	-0.1	0.5	0.1	0.0	0.3	0.2	-0.5
Reaction Time	0.2	0.3	1.6	-1.3	-0.6	-0.6	-0.4	0.2	-0.8	-0.7	-0.3	0.1	0.2	-0.8	0.3	0.6	0.1	0.1	-0.1
Breast Cancer	0.2	0.5	1.4	-0.4	0.1	-0.1	0.8	1.0	-1.2	-1.1	-0.7	0.7	0.5	0.2	-0.0	-0.6	0.9	0.6	0.8
Body Mass Index (BMI) (2010)	0.2	0.3	3.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.9	-1.0	0.3
Cardiovascular Disease	0.2	0.6	1.7	0.8	0.4	0.2	1.2	-0.4	-0.9	-0.2	0.3	-0.1	1.3	0.9	-0.4	1.1	0.6	1.2	1.0
Type 2 Diabetes (T2D) (2018)	0.2	0.5	2.0	0.6	-0.9	-0.2	0.8	-1.0	0.2	0.3	-0.4	-1.4	-0.4	0.1	-1.2	-0.4	-0.7	-0.1	0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.2	-0.4	-0.0	-0.1	-0.4	-0.0	-0.9	-0.4	-0.3	0.0	0.8	-0.3	1.1	0.2	0.7	-0.0	0.0
Ever had hysterectomy (womb removed)	0.2	0.3	1.4	0.8	0.4	0.6	0.2	-0.1	0.4	0.1	0.1	-0.3	1.2	1.1	-0.1	-0.0	0.1	0.5	-0.1
Systolic blood pressure, automated reading	0.2	0.6	2.0	-1.3	0.2	-0.3	-0.2	-0.4	-1.1	0.2	-0.1	-0.0	-0.5	0.0	-1.4	1.3	-0.5	-0.4	1.1
Medication: Co-codamol	0.2	0.3	1.4	0.5	0.3	0.2	-0.1	0.1	-0.3	0.0	0.3	0.1	1.2	0.2	0.6	-0.2	0.6	0.6	-1.1
Trunk fat percentage	0.2	0.8	3.0	-0.9	0.4	-0.4	-0.3	1.0	-1.7	-0.3	0.2	1.1	0.6	-0.1	-1.7	0.1	1.1	0.6	1.4
Townsend deprivation index at recruitment	0.2	0.3	2.2	-1.0	-0.3	-0.8	0.3	-0.1	-1.5	-0.2	-0.5	-0.0	0.4	-0.4	-0.6	0.3	0.2	0.3	0.4
Age when periods started (menarche)	0.2	0.5	1.4	0.8	-0.5	0.3	-1.2	-1.0	-0.7	-0.0	-0.5	-0.7	0.2	0.4	0.9	-0.4	-0.1	-0.8	-1.2
Trunk fat mass	0.2	0.9	6.5	-0.7	-0.3	-0.7	-0.6	0.1	-2.5	-0.7	-0.4	0.3	0.3	-0.1	-2.2	0.0	0.4	-0.2	0.9
Forced vital capacity (FVC)	0.2	0.8	4.6	0.4	-0.9	-0.6	-0.4	-0.6	-1.0	-0.7	-1.1	-0.5	-2.1	-0.7	-0.3	-0.5	-0.4	-1.0	-1.1
Qualifications: None of the above	0.2	0.5	1.3	0.5	0.5	0.5	0.9	0.2	-1.1	0.6	1.0	-0.0	0.6	-0.1	-0.6	0.2	0.5	1.1	1.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.8	0.3	-1.2	-0.6	0.0	-0.8	-0.5	-1.1	-0.8	-1.1	-1.2	-1.0	-0.3	-0.9	-1.0	-1.0	-1.3
Happiness	0.2	0.3	2.6	-0.5	0.3	0.1	0.0	0.3	0.0	-0.7	0.4	0.2	-1.6	0.4	0.4	-0.2	0.1	-0.3	-0.2
Medication: Cholesterol lowering	0.2	0.3	1.4	0.4	0.1	-0.2	1.2	0.7	-0.4	-0.1	0.4	0.4	0.8	-0.1	0.2	-0.4	-0.8	0.5	0.7
Exposure to tobacco smoke at home	0.2	0.2	0.7	0.5	0.2	0.5	-0.1	-0.8	0.3	0.1	0.3	-0.1	0.2	0.0	-0.6	0.2	0.8	0.5	0.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	2.6	-0.4	0.1	0.0	-1.3	-0.5	-0.1	-0.0	-0.4	-0.1	-1.6	0.1	-0.3	0.9	0.7	-0.5	-0.4
Body fat percentage	0.2	1.0	4.9	-1.1	0.1	-0.7	-0.3	0.8	-2.2	-0.5	0.0	0.8	0.9	-0.4	-1.8	-0.0	0.6	0.2	1.5
Medication: Blood pressure	0.2	0.4	3.2	0.5	0.4	0.3	0.7	0.7	0.1	-0.4	0.6	0.6	1.8	0.2	-0.1	-0.5	-0.1	0.6	0.5
Back pain experienced in last month	0.2	0.3	1.3	-0.9	0.1	-0.4	-0.6	0.6	-0.3	-0.8	-0.0	0.3	1.1	-0.1	0.0	-0.6	-0.2	-0.3	-0.3
Leg fat percentage (left)	0.2	0.8	5.6	-0.9	-0.1	-0.9	-0.3	0.3	-2.4	-0.3	-0.0	0.3	0.3	-0.6	-1.7	-0.4	-0.4	-0.6	1.4
Commuting to job workplace: Cycle	0.2	0.3	1.2	0.3	-0.2	-0.1	-0.2	-0.3	0.4	-0.0	-0.5	0.5	-0.4	-0.4	1.1	-1.0	0.3	-0.2	-1.1
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.1	0.5	-0.7	-0.3	-0.1	-0.5	1.1	0.7	-0.8	-0.6	-1.0	-0.6	0.2	-0.8	-0.2	-0.7	-1.0
Supplements: Calcium	0.2	0.3	1.2	0.2	-0.2	0.3	-0.3	-1.1	-0.1	-0.4	-0.1	-0.8	-1.1	0.3	-0.1	0.7	-0.6	-0.1	-0.1
HDL Cholesterol	0.1	0.2	2.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.7	1.6
Triglycerides	0.1	0.2	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.6	0.0	0.4
Systolic Blood Pressure	0.1	0.7	3.4	-0.1	-0.3	-0.3	0.2	-1.8	0.5	-1.1	-0.6	-1.2	1.8	0.5	-0.7	0.5	-0.2	-0.0	-0.1
Taking other prescription medications	0.1	0.2	0.4	-0.0	-0.3	-0.1	-0.2	-0.2	-0.6	-0.1	-0.7	-0.3	-0.5	0.6	0.1	-0.3	0.6	0.1	-0.6
Peak expiratory flow (PEF)	0.1	0.2	1.2	-0.7	-0.0	-0.3	-0.3	0.6	-0.5	-0.5	0.1	0.7	-1.1	-0.3	-0.1	0.2	0.4	-0.0	-0.4
Exposure to tobacco smoke outside home	0.1	0.1	0.5	-0.3	-0.2	-0.3	-0.4	-0.2	-0.2	-0.4	-0.1	0.3	-0.2	0.0	-0.1	-0.1	0.7	-0.3	-0.7
Loneliness, isolation	0.1	0.2	0.9	-0.1	0.0	-0.0	0.8	-0.0	-0.4	-0.2	0.1	-0.1	0.4	0.5	-0.5	-0.7	0.9	0.3	0.3
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.4	4.0	-0.9	1.5	1.0	-0.2	1.4	0.8	0.6	0.9	1.6	-1.0	0.6	1.0	0.2	2.0	1.6	1.6

Hub : Genes

POLR2E

Models

Trait associations