Best TWAS P=3.69e-09 · Best GWAS P=1.33e-09 conditioned to 0.0303
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | NEURL2 | 0.17 | 0.09 | lasso | 4 | 0.03 | 8.7e-03 | -5.7 | 5.8 | 6.1e-09 | -0.98 | 0.01 | 0.95 | FALSE |
| 2 | METSIM | Adipose | CD40 | 0.07 | 0.04 | lasso | 4 | 0.05 | 3.5e-08 | 5.0 | -5.7 | 1.2e-08 | 0.36 | 0.26 | 0.74 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MMP9 | 0.02 | 0.02 | blup | 46 | 0.02 | 3.5e-03 | -5.2 | 5.3 | 1.1e-07 | -0.88 | 0.02 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | MMP9 | 0.03 | 0.01 | blup | 46 | 0.01 | 6.7e-02 | -5.7 | 5.9 | 3.7e-09 | -0.72 | 0.01 | 0.72 | TRUE |