TWAS hub - CD40

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0550	0.0260	1.2e-02	0.002	-0.002	-0.002	-0.001	0.001	1.7e-01	8.1e-01	9.2e-01	4.6e-01	2.5e-01
2	GTEx	Adipose Subcutaneous	0.0930	0.0410	7.3e-03	0.012	NA	0.035	NA	0.050	3.2e-02	NA	6.9e-04	NA	6.0e-05
3	GTEx	Adrenal Gland	0.2175	0.0727	2.5e-03	0.030	NA	0.063	NA	0.055	3.0e-02	NA	2.8e-03	NA	4.9e-03
4	GTEx	Brain Cortex	0.3590	0.1100	2.2e-03	-0.006	NA	-0.006	NA	-0.011	5.2e-01	NA	5.1e-01	NA	8.9e-01
5	GTEx	Cells Transformed fibroblasts	0.2480	0.0580	3.6e-07	0.108	NA	0.122	NA	0.148	1.8e-08	NA	2.0e-09	NA	3.5e-11
6	GTEx	Nerve Tibial	0.1323	0.0429	5.9e-04	0.008	NA	0.010	NA	0.020	8.2e-02	NA	6.3e-02	NA	1.4e-02
7	GTEx	Skin Sun Exposed Lower leg	0.1250	0.0430	1.1e-03	0.083	NA	0.054	NA	0.079	2.3e-07	NA	2.9e-05	NA	4.1e-07
8	GTEx	Whole Blood	0.1210	0.0350	1.2e-04	0.067	NA	0.075	NA	0.074	8.6e-07	NA	1.8e-07	NA	2.4e-07
9	METSIM	Adipose	0.0745	0.0219	7.2e-06	0.037	0.033	0.044	0.037	0.051	2.5e-06	8.7e-06	2.8e-07	3.0e-06	3.5e-08
10	NTR	Blood	0.0322	0.0123	9.3e-04	0.003	0.006	0.007	0.007	0.008	2.2e-02	3.8e-03	1.6e-03	2.5e-03	1.1e-03
11	YFS	Blood	0.1037	0.0224	8.8e-14	0.048	0.050	0.047	0.054	0.049	2.8e-15	5.9e-16	2.9e-15	3.8e-17	9.0e-16
12	TCGA	Breast Invasive Carcinoma	0.0616	0.0242	1.9e-10	0.054	0.059	0.048	NA	0.049	3.5e-11	3.3e-12	3.3e-10	NA	2.5e-10
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0407	0.0170	5.3e-05	0.022	0.038	0.040	NA	0.031	1.6e-03	4.0e-05	2.2e-05	NA	1.8e-04
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1040	0.0430	4.2e-05	0.008	0.093	0.064	NA	0.068	1.1e-01	5.8e-06	1.6e-04	NA	1.0e-04
15	TCGA	Brain Lower Grade Glioma	0.0762	0.0266	6.2e-10	0.060	0.087	0.086	NA	0.083	2.3e-07	4.4e-10	5.8e-10	NA	1.2e-09
16	TCGA	Stomach Adenocarcinoma	0.0590	0.0270	8.6e-04	0.014	0.040	0.021	NA	0.022	3.0e-02	6.7e-04	1.1e-02	NA	9.0e-03
17	TCGA	Thyroid Carcinoma	0.0290	0.0160	5.4e-03	0.001	0.014	0.005	NA	0.004	2.4e-01	1.4e-02	8.6e-02	NA	1.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Rheumatoid Arthritis	14.9	20.6	30.6	4.9	4.5	3.8	5.1	5.1	4.4	2.1	5.4	3.5	2.9	5.4	5.4	5.0	5.2	4.7	5.5
Depressed Affect (Nagel 2018)	12.5	26.4	42.0	-4.8	-5.1	-2.5	-5.8	-6.0	-5.7	-0.7	-5.9	-4.3	-2.3	-6.2	-6.3	-6.5	-6.3	-5.6	-6.4
Neuroticism (Nagel 2018)	10.3	24.2	41.2	-4.0	-4.8	-3.3	-4.9	-5.9	-5.4	-2.2	-6.4	-4.7	-3.1	-5.9	-5.9	-6.4	-5.8	-4.6	-5.6
Neuroticism	9.5	22.8	42.7	-3.9	-4.9	-4.2	-5.0	-5.6	-5.5	-1.9	-6.2	-4.3	-3.0	-5.1	-5.8	-6.5	-5.5	-4.0	-5.2
Fed-up feelings	8.1	14.8	28.1	-4.3	-3.8	-2.0	-4.0	-4.4	-3.9	-0.2	-3.9	-3.1	-0.7	-4.7	-4.7	-4.5	-4.9	-4.8	-5.3
Miserableness	7.8	13.5	23.7	-3.6	-4.5	-2.2	-4.1	-3.8	-4.2	0.6	-3.4	-2.6	-0.8	-4.0	-4.7	-4.2	-4.7	-4.6	-4.9
Depression (Nagel 2018)	7.3	11.0	19.6	-3.5	-3.4	-0.5	-2.7	-3.8	-3.9	-0.8	-4.1	-2.4	-1.8	-4.2	-4.4	-4.0	-4.2	-3.4	-4.2
Neuroticism score	7.3	15.1	27.8	-3.1	-4.1	-3.7	-3.8	-4.5	-4.4	-1.1	-4.7	-3.4	-2.0	-4.5	-4.7	-5.3	-4.5	-3.9	-4.5
Crohns Disease (2017)	7.2	15.8	32.5	-3.5	-3.9	-1.7	-3.7	-3.5	-3.8	-3.3	-5.7	-5.0	-3.1	-5.1	-4.5	-4.9	-4.9	-3.3	-3.9
Mood swings	7.0	12.6	21.2	-3.0	-3.7	-1.6	-4.4	-4.3	-4.4	1.2	-3.6	-2.2	-0.7	-4.1	-4.4	-4.6	-4.2	-4.1	-4.6
Average weekly spirits intake	6.7	8.3	16.0	-3.7	-2.8	-1.1	-3.1	-2.6	-3.4	-0.1	-2.9	-2.2	0.1	-3.5	-3.6	-2.9	-4.0	-3.5	-3.9
Guilty feelings	6.3	9.4	17.7	-3.2	-4.0	-1.1	-3.2	-2.6	-4.0	0.1	-3.0	-1.8	0.3	-3.5	-4.1	-4.2	-3.6	-3.7	-3.7
Bipolar Disorder (2018)	5.4	8.5	13.8	-2.6	-2.5	-2.5	-2.5	-3.3	-2.1	-2.8	-3.5	-3.7	-2.8	-3.5	-3.0	-2.8	-3.7	-3.1	-3.1
Allergy or Eczema	5.2	13.7	37.5	3.5	3.1	3.9	3.3	6.1	2.6	0.6	4.0	3.4	3.1	5.0	3.7	3.5	4.3	3.9	4.3
Seen doctor (GP) for nerves, anxiety, tension or depression	5.0	7.6	19.1	-1.9	-1.2	-1.5	-1.4	-4.1	-1.2	-2.5	-3.9	-4.4	-3.3	-3.8	-2.2	-2.9	-3.5	-2.4	-2.3
Bipolar Disorder or Schizophrenia	4.7	11.5	23.4	-2.8	-2.1	-2.1	-2.9	-4.3	-2.7	-3.3	-4.8	-4.5	-3.7	-4.0	-3.5	-3.4	-4.4	-2.7	-3.3
Irritable Bowel Disease (IBD)	4.6	11.0	20.8	-2.8	-3.0	-0.2	-3.5	-3.7	-3.3	-1.8	-4.6	-4.1	-1.9	-4.3	-3.7	-4.2	-4.0	-3.3	-3.5
Frequency of depressed mood in last 2 weeks	4.4	6.2	11.5	-2.3	-2.7	-0.9	-1.7	-2.6	-2.6	-0.2	-3.0	-2.3	-1.3	-3.3	-3.1	-2.6	-3.4	-3.0	-3.4
Hayfever/allergic rhinitis (self-reported)	4.4	5.9	13.9	2.4	2.5	2.0	2.7	3.7	2.4	0.1	2.7	1.4	1.4	2.9	2.8	2.9	2.6	2.2	3.0
Unable to work because of sickness or disability	4.1	5.4	13.2	-1.8	-2.5	0.6	-1.9	-3.6	-2.3	-0.1	-2.8	-1.9	-0.7	-3.2	-2.6	-2.6	-2.5	-3.0	-3.0
Chronotype (morning person)	3.8	8.8	16.9	2.8	3.4	1.1	2.2	4.1	3.3	-0.1	3.6	3.0	0.0	4.1	3.5	3.5	3.0	3.4	3.7
Crohns Disease (2012)	3.7	5.9	13.8	-1.8	-2.3	-2.1	-2.6	-2.2	-3.0	-1.3	-3.7	-1.7	-1.6	-3.1	-3.1	-3.3	-2.8	-1.6	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	3.7	4.8	17.6	-1.2	-0.9	-1.2	-0.3	-2.7	-0.5	-3.3	-2.9	-4.2	-3.5	-2.4	-1.4	-1.7	-2.6	-1.5	-1.6
Worry (Nagel 2018)	3.6	7.6	17.6	-1.4	-1.8	-3.4	-1.8	-3.6	-2.1	-3.2	-4.2	-3.5	-3.9	-2.7	-2.4	-3.4	-2.6	-0.8	-1.9
Loneliness, isolation	3.6	5.0	8.7	-1.3	-1.1	-1.8	-2.0	-3.0	-1.4	-1.8	-2.7	-2.4	-2.8	-2.7	-2.1	-2.8	-2.6	-2.8	-2.4
High cholesterol (Self-reported)	3.2	5.7	12.5	2.7	2.5	1.2	3.4	1.1	3.1	1.6	3.5	1.3	1.4	2.2	3.2	3.3	2.7	1.0	2.3
Smoking Status	3.0	7.3	19.9	-2.5	-2.5	-2.9	-2.5	-3.5	-1.8	0.1	-2.0	-2.8	-0.7	-3.7	-2.3	-3.2	-2.7	-4.5	-3.5
Sensitivity / hurt feelings	3.0	5.1	11.2	-1.8	-1.2	-1.3	-2.0	-3.3	-2.0	-1.2	-3.0	-2.9	-2.1	-2.8	-2.3	-2.6	-2.8	-1.9	-2.4
Knee pain experienced in last month	3.0	4.7	9.6	-2.6	-1.6	-1.6	-3.0	-2.7	-2.4	-0.4	-1.6	-1.6	-0.8	-2.0	-2.6	-2.4	-2.8	-2.4	-3.1
Diabetes (father)	2.9	3.5	10.4	1.7	1.0	3.2	0.9	2.1	1.4	2.1	2.3	1.5	1.0	2.9	2.0	1.1	2.4	1.8	1.8
Mean Putamen Volume	2.8	3.2	10.9	-2.1	-1.7	-0.1	-0.9	-2.3	-1.4	1.1	-0.9	-1.2	0.2	-2.9	-1.8	-1.7	-2.1	-3.3	-2.6
Neuroticism (2016)	2.8	4.0	9.8	-0.8	-1.2	-1.7	-2.6	-2.6	-3.0	1.0	-2.8	-1.0	0.1	-2.3	-2.7	-3.1	-2.0	-1.1	-2.0
Schizophrenia (2014)	2.8	6.1	14.3	-2.3	-1.1	-1.1	-2.1	-3.4	-1.9	-2.7	-3.8	-3.0	-3.1	-2.8	-2.6	-2.3	-3.1	-1.3	-2.4
Bipolar Disorder (2011)	2.7	2.6	5.2	-0.9	-1.9	-0.9	-2.1	-2.1	-1.0	-1.2	-2.3	-2.2	-1.6	-1.5	-1.4	-2.1	-2.0	-1.1	-1.3
HDL Cholesterol	2.7	4.5	9.9	2.0	1.2	3.2	2.6	2.3	2.7	-3.0	0.3	-1.5	-1.5	1.9	2.0	2.6	1.2	2.4	2.6
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.4	13.9	-1.9	-1.8	0.1	-0.9	-2.6	-1.8	-0.1	-1.5	-2.3	-0.9	-3.4	-2.2	-1.5	-2.6	-3.7	-3.0
Maternal smoking around birth	2.6	3.7	8.5	-2.1	-1.2	-1.5	-2.1	-2.9	-1.1	-0.9	-1.2	-2.0	-1.4	-2.2	-1.8	-2.1	-2.5	-2.7	-2.5
Hayfever, allergic rhinitis or eczema	2.6	5.6	16.0	2.2	2.5	2.7	1.9	4.0	2.0	0.2	2.3	1.8	1.7	3.1	2.6	2.0	2.7	2.5	2.8
Allergy	2.5	5.7	15.2	-2.3	-2.9	-2.7	-1.8	-3.9	-2.3	-0.1	-2.4	-1.5	-1.1	-3.3	-2.8	-1.9	-2.6	-2.5	-2.8
Health satisfaction	2.5	3.3	9.4	-1.7	-1.3	-1.9	-0.8	-2.8	-1.0	-0.4	-1.5	-2.0	-0.3	-2.6	-1.6	-1.6	-2.1	-3.1	-2.6
Neck or shoulder pain in last month	2.5	3.5	9.6	-2.1	-1.0	-0.3	-2.6	-2.5	-1.1	-0.9	-1.5	-1.8	-1.3	-1.9	-1.8	-2.0	-2.4	-3.1	-2.6
Worrier / anxious feelings	2.4	4.5	12.0	-0.5	-1.3	-2.9	-0.4	-3.5	-1.5	-1.6	-3.1	-3.0	-2.1	-3.0	-1.7	-2.6	-1.8	-1.3	-1.5
Depression (self-reported)	2.4	2.9	6.1	-1.5	-1.3	-0.2	-1.2	-2.3	-1.2	-1.0	-2.3	-2.0	-1.8	-2.4	-1.8	-2.5	-2.2	-1.1	-1.7
Illnesses of siblings: Diabetes	2.4	3.0	6.4	-2.0	-2.5	-0.2	-2.3	-0.3	-2.4	2.0	-0.5	0.2	0.6	-1.3	-2.1	-1.9	-1.9	-2.3	-2.5
Irritability	2.4	4.0	8.8	-1.4	-2.4	-1.1	-1.7	-2.1	-3.0	0.4	-2.3	-1.3	0.1	-2.1	-2.7	-2.8	-2.4	-2.2	-2.4
Ever had prostate specific antigen (PSA) test	2.4	2.8	4.8	-1.4	-2.2	0.1	-1.7	-2.1	-2.2	-0.4	-1.9	-1.5	-1.0	-2.0	-2.1	-1.9	-1.8	-1.8	-1.8
Major Depression (MDD)	2.3	2.8	6.0	-1.6	-0.9	-0.7	-1.1	-2.0	-1.2	-1.1	-2.1	-2.2	-1.2	-2.4	-1.7	-1.8	-2.4	-1.8	-1.9
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.6	6.7	-1.3	-2.5	-2.1	-1.9	-2.1	-2.4	0.2	-2.0	-1.1	-0.4	-1.9	-2.4	-2.6	-2.0	-2.2	-2.3
Smoking status: Current	2.2	3.5	9.1	-1.8	-1.8	-1.9	-1.6	-2.5	-1.2	-0.5	-1.1	-2.5	-1.2	-2.2	-1.5	-1.9	-2.1	-3.0	-2.5
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	5.8	-2.2	-1.8	-1.9	-2.4	-0.6	-1.8	0.7	-0.9	-0.6	-0.1	-1.3	-1.8	-1.6	-1.9	-1.6	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.4	8.3	1.7	0.8	2.9	1.6	1.3	0.9	2.2	1.9	1.7	1.3	1.2	1.4	1.5	1.4	1.1	1.4
Ever taken oral contraceptive pill	2.1	2.3	4.5	-1.3	-1.8	-0.6	-1.5	-1.1	-1.1	-1.6	-1.7	-1.8	-0.8	-1.7	-1.4	-2.1	-1.7	-2.1	-1.8
Risk taking	2.1	3.0	9.7	-1.5	-1.6	-0.4	-2.0	-1.4	-1.7	0.8	-1.2	-1.2	-0.1	-2.4	-1.8	-2.2	-1.9	-3.1	-2.5
Schizophrenia (2018)	2.0	4.2	11.3	-1.5	-0.6	-0.6	-1.7	-2.9	-1.7	-2.0	-3.4	-2.8	-2.5	-2.3	-2.1	-2.1	-2.6	-1.0	-1.8
Medication: Co-codamol	2.0	2.3	8.4	-1.1	-1.4	-0.1	-1.2	-2.7	-1.1	-0.8	-2.1	-2.9	-1.8	-1.3	-1.2	-1.4	-1.5	-0.4	-1.6
Mouth/teeth dental problems	1.9	2.8	10.4	1.2	1.9	0.4	1.7	2.4	1.4	-0.7	1.0	0.8	-0.8	2.3	1.6	1.7	1.5	3.2	2.5
Suffer from ‘nerves’	1.9	2.9	6.8	-1.2	-0.9	-1.7	-1.3	-1.9	-1.1	-1.8	-2.6	-2.6	-2.5	-1.6	-1.5	-2.0	-1.8	-0.7	-1.6
Back pain experienced in last month	1.9	2.7	13.1	-1.4	0.7	-0.1	-0.5	-3.0	0.6	-1.3	-0.6	-3.6	-2.6	-1.8	-0.3	-0.1	-1.8	-1.8	-1.6
Current tobacco smoking	1.8	2.9	8.7	-1.7	-1.8	-1.8	-1.7	-2.1	-1.3	-0.0	-0.7	-2.0	-1.0	-1.9	-1.5	-1.8	-1.8	-3.0	-2.4
Trunk fat-free mass	1.8	10.3	18.7	-3.7	-3.3	-2.3	-1.8	-2.1	-3.5	-1.0	-3.7	-3.7	-1.2	-4.3	-3.9	-3.9	-4.2	-3.5	-4.1
Trunk predicted mass	1.8	10.5	19.0	-3.7	-3.3	-2.4	-1.8	-2.2	-3.5	-1.0	-3.7	-3.7	-1.2	-4.4	-3.9	-3.9	-4.2	-3.6	-4.1
Commuting to job workplace: Car/motor vehicle	1.8	2.1	11.4	1.2	1.4	3.4	0.9	0.2	1.1	1.6	1.6	1.4	1.0	1.4	1.4	1.7	1.6	0.9	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.6	-1.3	-2.1	0.5	-1.6	-1.6	-2.0	-0.6	-2.1	-0.7	-2.0	-0.9	-1.9	-1.5	-1.2	-0.2	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	3.6	-1.1	-1.2	-1.9	-1.5	-1.8	-1.2	0.4	-1.6	-1.1	-1.6	-1.9	-1.3	-1.3	-1.8	-1.6	-1.4
Family relationship satisfaction	1.7	2.1	5.3	-1.8	-2.3	-1.7	-1.4	-1.2	-1.8	-0.2	-1.1	-0.8	-0.7	-1.1	-1.9	-1.4	-1.9	-1.2	-1.9
Supplements: Calcium	1.7	1.9	4.9	1.3	1.2	1.0	0.7	1.5	0.8	0.1	1.4	1.4	1.4	2.1	1.2	1.2	1.9	2.2	1.8
Intelligence (Savage-Jansen 2018)	1.6	5.0	17.1	1.7	1.4	-0.0	1.7	4.1	1.3	1.2	3.8	3.1	2.7	2.7	2.0	2.3	2.4	0.8	1.9
Lupus	1.6	2.5	5.9	-2.2	-0.7	-0.2	-2.2	-1.5	-1.6	-0.2	-2.0	-1.7	-1.6	-1.4	-2.0	-1.5	-2.4	-0.1	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	4.4	-1.6	-1.5	0.1	-1.4	-2.1	-1.9	0.7	-1.4	-0.6	-0.8	-1.4	-1.9	-1.5	-1.8	-1.5	-2.0
Nervous feelings	1.6	3.0	7.7	-0.5	-1.2	-2.8	-1.6	-2.1	-1.3	-2.1	-2.7	-2.2	-2.4	-1.2	-1.4	-2.4	-1.2	0.0	-0.8
Asthma	1.6	3.1	5.7	2.4	1.8	1.8	1.8	1.8	1.6	1.5	1.6	1.4	1.1	2.3	2.1	1.9	1.9	1.6	2.0
Average weekly red wine intake	1.6	2.4	7.4	-1.6	-0.2	-2.3	-1.6	-1.0	-1.2	-2.7	-1.8	-1.5	-1.9	-1.3	-1.5	-1.1	-2.0	-1.0	-1.4
Alcohol drinker status: Never	1.6	1.9	9.7	-0.7	-0.6	-0.1	-0.6	-2.9	-0.7	-0.9	-1.6	-3.1	-1.6	-1.4	-1.0	-0.9	-1.6	-0.5	-1.1
Arm predicted mass (left)	1.6	8.3	15.9	-3.6	-3.0	-1.3	-1.6	-1.8	-3.2	-0.1	-2.9	-3.0	-0.6	-3.9	-3.5	-3.4	-3.8	-3.6	-4.0
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.6	-1.2	-1.8	0.4	-1.3	-0.3	-1.9	1.3	-0.5	-1.1	0.1	-0.9	-1.7	-1.6	-1.5	-1.6	-1.9
Alcohol usually taken with meals	1.5	2.5	8.0	0.2	2.2	-2.7	1.4	0.3	1.6	-2.7	-0.6	-0.9	-1.8	0.5	1.2	0.8	0.7	2.8	1.6
Qualifications: None of the above	1.5	3.2	10.0	-1.7	-1.5	0.6	-2.3	-3.2	-1.7	0.2	-1.3	-1.1	-1.2	-1.8	-2.0	-1.9	-2.2	-2.1	-2.4
Time employed in main current job	1.5	1.8	3.7	-1.6	-1.8	-1.0	-0.5	-1.9	-0.9	-1.1	-1.7	-1.0	-0.0	-1.7	-1.5	-1.0	-1.8	-1.1	-1.6
Medication: Amlodipine	1.5	2.1	7.6	-0.5	0.7	-1.8	-0.2	-2.8	0.4	-1.6	-1.7	-2.4	-2.4	-2.1	-0.2	-0.6	-1.4	-0.7	-0.5
Arm predicted mass (right)	1.5	7.5	14.3	-3.3	-3.0	-1.7	-1.4	-1.6	-3.0	0.1	-2.6	-2.7	-0.5	-3.8	-3.3	-3.2	-3.6	-3.7	-3.8
Whole body fat-free mass	1.5	8.6	16.2	-3.4	-3.1	-1.5	-1.6	-1.8	-3.3	-0.5	-3.2	-3.3	-0.8	-4.0	-3.6	-3.4	-3.9	-3.5	-3.9
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	3.1	-1.8	-0.1	0.2	-1.4	-0.8	-1.3	-1.0	-1.4	-0.4	-0.4	-1.7	-1.7	-1.7	-1.7	-1.5	-1.6
High blood pressure (mother)	1.4	1.9	7.2	-1.1	0.3	-0.7	-1.0	-0.9	0.6	-2.7	-1.4	-2.7	-2.3	-1.7	-0.3	-0.4	-1.7	-1.0	-0.8
Number of incorrect matches in round	1.4	2.3	6.3	-1.4	-0.9	-0.9	-1.7	-2.4	-0.9	-0.9	-1.9	-1.9	-2.5	-1.8	-1.3	-1.3	-1.7	-0.6	-1.3
Forced vital capacity (FVC)	1.4	5.2	11.7	-2.7	-3.4	-1.1	-2.4	-0.1	-2.6	-1.3	-3.1	-2.1	-1.4	-1.9	-2.9	-3.2	-2.8	-1.6	-2.2
Ever unenthusiastic/disinterested for a whole week	1.4	1.8	4.2	-1.4	-1.4	-1.1	-1.2	-1.2	-1.4	-1.3	-1.7	-1.2	-1.3	-1.4	-1.7	-1.1	-2.0	-0.6	-1.3
Alcohol intake versus 10 years previously	1.4	2.1	5.6	1.4	1.6	0.8	1.3	1.5	1.1	1.8	2.4	1.7	1.4	1.7	1.5	1.6	1.5	0.8	1.3
Falls in the last year	1.4	2.0	4.0	-1.7	-1.3	-0.6	-1.5	-1.5	-0.9	-1.2	-1.2	-1.4	-1.1	-1.7	-1.3	-1.5	-2.0	-1.7	-1.7
Birth weight of first child	1.4	2.6	9.7	-1.6	-1.5	-2.1	-0.2	-1.1	-1.1	-0.4	-1.5	-1.3	1.1	-3.1	-1.5	-1.0	-1.9	-2.5	-1.9
Loud music exposure frequency	1.4	1.6	5.0	1.0	2.2	-1.5	1.1	0.9	1.7	-0.4	0.7	-0.3	-0.7	0.9	1.6	0.5	1.3	2.1	1.6
Arm fat-free mass (right)	1.4	7.3	14.4	-3.4	-2.8	-1.4	-1.4	-1.8	-2.9	0.1	-2.5	-2.8	-0.7	-3.7	-3.2	-3.1	-3.6	-3.6	-3.8
Overall health rating	1.4	2.9	9.6	-1.4	-0.6	-0.9	-1.4	-3.0	-0.7	0.1	-1.1	-1.9	-1.0	-2.5	-1.1	-1.9	-1.9	-3.1	-2.3
Long-standing illness, disability or infirmity	1.4	2.2	6.5	-1.5	0.2	0.1	-1.0	-2.5	-0.5	0.4	-0.8	-1.6	-0.3	-2.4	-1.0	-1.7	-1.7	-2.5	-2.2
Whole body water mass	1.4	8.0	15.1	-3.3	-3.1	-1.5	-1.5	-1.7	-3.3	-0.3	-3.1	-3.0	-0.6	-3.9	-3.5	-3.4	-3.7	-3.4	-3.8
Arm fat-free mass (left)	1.4	6.9	13.4	-3.4	-2.7	-1.0	-1.3	-1.5	-2.9	-0.2	-2.6	-3.0	-0.6	-3.6	-3.2	-3.0	-3.5	-3.3	-3.7
Father’s age at death	1.3	1.7	3.6	1.0	1.6	-0.2	0.8	1.9	1.3	0.2	1.4	1.9	0.7	1.7	1.5	1.3	1.6	1.4	1.6
Commuting to job workplace: Public transport	1.3	1.5	12.3	-0.9	-1.3	-3.5	-0.9	0.2	-1.4	-0.3	-0.8	-0.5	0.5	-1.0	-1.3	-1.4	-1.1	-0.1	-0.8
Ever smoked	1.3	2.3	7.1	-2.2	-1.4	-1.7	-1.4	-1.2	-1.1	0.4	-0.4	-0.8	0.9	-2.0	-1.3	-1.4	-1.5	-2.7	-2.3
Basal metabolic rate	1.3	7.3	14.3	-3.2	-2.8	-1.1	-1.4	-1.8	-3.0	-0.2	-2.9	-3.2	-0.6	-3.8	-3.3	-3.1	-3.6	-3.3	-3.7
Number of operations (self-reported)	1.3	1.9	5.0	-2.2	-0.7	0.3	-1.8	-1.7	-1.1	0.9	-0.9	-0.8	-0.0	-1.7	-1.5	-1.3	-1.6	-1.6	-2.1
Alzheimer’s Disease (in mother)	1.2	1.4	5.3	-0.6	-1.1	0.1	-1.0	-2.3	-1.6	-0.8	-1.8	-1.0	-0.7	-1.0	-1.5	-1.0	-1.2	-1.1	-1.4
Primary Biliary Cirrhosis	1.2	1.7	4.7	-0.6	0.6	-0.2	0.6	-2.2	0.1	-1.9	-1.8	-1.9	-1.8	-2.2	-0.5	-0.8	-1.1	-1.1	-0.9
Hearing difficulty/problems: Yes	1.2	1.8	4.7	1.7	1.1	0.4	0.4	1.6	0.8	1.8	1.5	1.5	2.2	1.5	1.3	0.4	1.9	0.8	1.2
Average weekly fortified wine intake	1.2	1.4	5.8	-0.7	-1.0	-1.9	-1.2	-2.4	-0.9	0.6	-0.9	-0.1	-0.0	-1.4	-1.2	-1.2	-0.7	-1.4	-1.5
Impedance of arm (left)	1.2	5.4	11.4	2.6	2.0	1.2	1.3	2.4	2.5	0.3	2.4	2.2	1.8	3.4	2.6	3.0	2.9	3.0	2.9
Forced vital capacity (FVC), Best measure	1.2	4.3	10.5	-2.4	-3.2	-0.1	-2.0	0.7	-2.6	-1.4	-2.8	-1.6	-0.5	-1.8	-2.7	-3.1	-2.5	-1.7	-2.0
Qualifications: College or University degree	1.2	3.7	18.9	1.3	1.1	-0.4	2.1	4.3	1.3	-0.0	1.5	1.4	2.2	2.0	1.8	1.4	2.1	2.7	2.3
Eye problems/disorders: None of the above	1.2	1.4	3.8	-0.6	-1.2	-1.7	-0.7	-0.9	-0.2	-1.6	-1.6	-1.4	-1.9	-1.1	-0.9	-1.4	-1.3	-0.8	-0.7
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	6.1	-0.8	-1.5	0.3	-1.3	-2.3	-1.1	-0.2	-1.4	-1.1	0.7	-2.1	-1.5	-1.2	-1.5	-2.5	-1.6
Asthma (self-reported)	1.2	2.4	5.7	2.4	1.6	1.6	1.6	1.2	1.6	1.2	1.2	0.9	0.6	1.9	2.0	1.7	1.8	1.4	1.9
Illnesses of father: High blood pressure	1.2	1.4	5.1	2.2	2.2	0.3	1.6	-0.6	1.6	-0.1	0.6	-0.5	-0.3	0.4	1.7	1.2	1.1	1.0	1.5
Schizophrenia vs Biploar Disorder	1.1	1.5	5.2	-2.3	-0.1	-0.4	-1.3	-0.8	-1.0	-1.2	-1.2	-0.7	-0.7	-1.6	-1.5	-0.8	-2.0	-0.8	-1.6
Age when periods started (menarche)	1.1	2.7	10.9	1.1	1.2	0.3	2.0	3.3	1.0	-1.3	1.6	0.8	0.7	2.4	1.3	2.2	1.0	2.1	1.9
Past tobacco smoking	1.1	2.0	5.9	1.7	1.0	1.4	1.6	1.5	0.9	-0.9	0.5	0.6	-1.1	2.0	1.1	1.5	1.2	2.4	2.2
Lung cancer (father)	1.1	1.2	4.1	-0.9	-1.3	-2.0	-1.7	-0.6	-1.4	1.4	-0.8	1.4	0.7	-0.3	-1.3	-1.1	-0.5	-0.1	-1.1
Length of working week for main job	1.1	1.2	3.0	-1.5	-1.1	0.3	0.1	-1.1	-0.5	-1.7	-0.9	-1.6	-1.1	-1.3	-1.0	-0.4	-1.2	-1.2	-1.4
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	8.5	0.4	1.7	1.3	1.4	2.9	1.1	0.1	1.6	1.5	1.4	1.2	1.2	1.3	1.0	0.4	1.3
Medication: Paracetamol	1.1	1.8	7.6	-0.2	0.3	-0.2	-0.2	-2.8	0.1	-0.9	-1.4	-2.4	-2.2	-1.8	-0.4	-1.0	-1.2	-1.7	-1.2
Age started oral contraceptive pill	1.1	1.3	4.7	1.1	0.3	0.8	1.8	0.7	1.0	-1.6	0.1	0.1	0.7	1.0	1.0	1.3	1.3	2.2	1.7
Alzheimer’s Disease (including proxy)	1.0	1.4	3.2	-0.8	-1.2	-0.1	-0.9	-1.8	-1.3	-1.6	-1.4	-1.2	-1.0	-1.1	-1.3	-1.0	-1.4	-1.3	-1.4
Triglycerides	1.0	1.7	11.8	-0.2	0.9	-2.3	-0.7	-0.4	-0.3	3.4	1.6	2.0	1.4	0.1	0.3	0.1	0.7	-0.5	-0.4
Respiratory disease	1.0	2.2	6.6	2.6	1.4	1.5	1.5	1.0	1.7	0.8	0.8	0.6	0.4	1.7	2.0	1.6	1.8	1.4	2.0
Systolic blood pressure, automated reading	1.0	3.0	8.3	0.3	2.6	0.8	0.9	2.0	1.7	-0.5	2.2	0.9	-0.2	2.6	1.7	2.7	1.3	2.9	1.7
Leg fat-free mass (left)	1.0	5.5	10.4	-2.7	-2.5	-0.6	-1.2	-1.4	-2.9	0.1	-2.5	-2.5	-0.3	-3.2	-3.0	-2.7	-3.1	-2.8	-3.2
Leg predicted mass (left)	1.0	5.2	10.0	-2.7	-2.5	-0.6	-1.2	-1.3	-2.8	0.1	-2.4	-2.4	-0.3	-3.1	-3.0	-2.6	-3.1	-2.8	-3.2
Financial difficulties in last 2 years	1.0	1.4	4.3	0.7	-1.9	1.3	-0.9	-2.1	-1.0	1.4	-0.5	-0.2	0.7	-1.1	-0.8	-1.2	-0.4	-2.0	-1.2
Impedance of arm (right)	1.0	4.9	10.9	2.2	2.1	1.5	1.2	2.4	2.2	-0.2	2.1	2.0	1.4	3.3	2.4	2.8	2.7	3.2	2.8
Leg pain on walking	1.0	1.2	3.8	-0.8	-0.3	-0.6	-1.3	-1.9	-1.0	0.5	-1.0	-1.1	-0.2	-1.4	-1.1	-1.3	-1.1	-1.4	-1.7
Leg fat-free mass (right)	1.0	5.3	10.6	-2.6	-2.4	-0.5	-1.1	-1.4	-2.6	-0.2	-2.6	-2.8	-0.7	-3.3	-2.9	-2.6	-3.1	-2.8	-3.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	10.4	-1.5	-3.2	0.3	-1.1	1.1	-2.4	0.5	-1.5	0.7	0.6	-0.4	-1.9	-2.3	-1.0	-0.4	-0.9
Leg predicted mass (right)	1.0	5.3	10.4	-2.6	-2.3	-0.5	-1.1	-1.4	-2.6	-0.2	-2.6	-2.7	-0.7	-3.2	-2.9	-2.6	-3.1	-2.8	-3.1
Medication: Paracetamol	1.0	1.6	6.4	-0.3	0.4	0.1	0.2	-2.1	0.5	-0.8	-1.2	-2.5	-2.5	-1.5	-0.2	-0.7	-1.2	-1.3	-1.0
Pain experienced in last month	1.0	1.7	4.1	1.5	0.3	0.4	2.0	2.0	0.5	1.0	0.8	2.0	0.9	1.3	1.0	1.5	1.5	1.5	1.7
LDL Cholesterol	0.9	1.4	2.7	0.8	1.5	-0.6	1.2	1.6	1.5	0.6	1.5	0.7	0.3	1.4	1.4	1.5	1.3	1.4	1.3
Blood Red Count	0.9	9.0	29.6	2.0	1.7	5.4	2.4	4.7	1.6	-0.8	1.6	0.9	0.2	4.7	2.1	3.0	2.9	5.0	3.6
Lung FVC	0.9	4.6	9.6	-2.9	-2.3	0.1	-3.1	-0.6	-2.6	-1.0	-2.5	-1.5	-1.2	-2.1	-2.9	-2.7	-3.0	-1.5	-2.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	6.3	-1.0	0.4	0.3	-1.1	-2.5	-0.5	-0.0	-1.0	-1.6	-0.2	-1.3	-0.8	-0.9	-1.2	-0.9	-1.5
Medication: Metformin	0.9	1.2	5.8	-1.1	-1.2	0.1	-1.9	-0.3	-1.6	2.4	0.0	0.8	0.7	-0.1	-1.2	-1.1	-0.7	-0.6	-1.3
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	6.6	-2.1	-2.6	-0.9	-1.3	-0.2	-1.5	-1.6	-2.4	-2.1	-1.7	-1.3	-2.0	-2.2	-2.1	-1.0	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	7.5	-2.3	-2.7	-0.0	-1.4	0.4	-2.0	-1.4	-2.4	-1.7	-0.7	-1.4	-2.2	-2.4	-2.2	-1.2	-1.7
High blood pressure (siblings)	0.9	1.3	5.6	0.4	2.4	-0.2	0.7	0.9	1.5	-0.6	0.7	-0.6	-1.3	1.2	1.3	1.3	0.7	1.8	1.2
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.2	-0.3	-0.3	-1.2	-0.7	-1.5	-0.7	1.8	-0.0	-0.4	0.9	-1.7	-0.6	-1.0	-0.5	-1.8	-1.4
Heart disease (mother)	0.9	1.1	2.6	-0.3	-0.4	-1.6	-1.2	-0.7	0.1	-1.5	-1.2	-1.4	-1.2	-0.9	-0.4	-1.2	-1.1	-1.5	-0.7
Illnesses of father: None of the above (group 1)	0.9	1.1	5.1	-1.1	-1.0	-1.1	-0.4	1.2	-0.9	1.4	1.2	2.2	1.8	0.6	-0.7	0.6	0.2	0.6	-0.4
Wears glasses or contact lenses	0.9	1.0	2.8	-0.3	-0.8	1.1	-0.0	-1.6	-1.3	-0.3	-1.7	-1.1	1.0	-1.5	-1.1	-1.0	-0.8	-0.5	-0.9
Financial situation satisfaction	0.9	1.1	2.8	-0.0	-1.4	-1.2	-1.2	-0.7	-0.8	1.7	0.2	1.0	1.6	-0.8	-0.7	-1.0	-0.3	-1.6	-1.2
Medication: Atorvastatin	0.9	1.1	3.7	0.6	0.9	0.1	1.0	1.1	1.5	0.9	1.9	0.7	1.0	1.1	1.4	1.1	1.1	0.1	0.8
Impedance of whole body	0.9	4.7	10.8	2.2	1.8	1.0	1.0	2.1	2.5	-0.0	2.4	2.0	1.2	3.3	2.6	3.0	2.7	2.6	2.7
Ulcerative Colitis (UC)	0.8	1.5	3.2	-0.6	-0.8	1.5	-1.3	-1.8	-1.3	0.6	-1.2	-1.2	0.6	-1.6	-1.2	-1.5	-1.2	-1.6	-1.4
Reaction Time	0.8	1.5	6.3	0.8	-1.6	2.2	0.3	2.0	-0.3	1.1	0.5	1.9	2.5	1.0	0.1	-0.0	0.8	-0.0	0.3
Ulcerative Colitis	0.8	1.2	4.4	0.0	-1.0	1.5	-1.2	-2.1	-1.0	1.0	-1.1	-0.6	0.4	-1.1	-0.9	-1.2	-0.7	-1.4	-1.2
Diabetes (mother)	0.8	1.0	2.5	1.0	1.4	0.2	1.0	0.5	1.0	0.2	1.2	1.0	0.2	1.1	1.2	1.6	1.3	1.1	1.1
Severe depression (siblings)	0.8	0.9	2.8	-0.4	-0.6	0.7	-0.0	-1.4	-0.4	-0.3	-1.2	-1.6	-0.3	-1.7	-0.7	-0.5	-1.1	-1.6	-1.1
Townsend deprivation index at recruitment	0.8	1.1	5.4	0.3	-1.1	1.5	-0.8	-0.6	-0.4	2.0	0.5	0.6	1.3	-0.4	-0.4	-1.2	0.1	-2.3	-1.1
Stomach or abdominal pain in last month	0.8	1.0	4.3	0.0	0.1	1.3	-1.3	-2.1	-0.2	0.0	-0.8	-1.0	-0.9	-1.1	-0.5	-0.7	-1.1	-1.6	-0.9
Pulse rate	0.8	1.3	7.4	-0.2	0.5	-0.7	0.2	1.6	-0.2	2.7	1.4	2.0	1.9	-0.2	-0.0	0.5	-0.4	-0.9	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.9	1.1	1.3	1.0	1.6	0.1	1.7	0.0	0.8	-0.2	0.0	0.5	1.4	1.0	1.0	0.4	1.0
Medication: Cholesterol lowering	0.8	1.3	4.9	2.2	1.3	0.3	1.5	-0.2	1.3	1.1	1.5	0.6	0.9	0.7	1.6	1.2	1.2	-0.3	1.0
Prospective memory result	0.8	1.0	5.2	-0.1	-0.4	-0.2	-0.6	-2.3	0.1	-0.8	-1.2	-2.0	-1.3	-1.2	-0.3	-0.4	-0.8	-0.7	-0.9
Pulse wave Arterial Stiffness index	0.8	0.9	3.3	0.6	-0.9	1.8	-0.4	-1.0	-0.4	1.2	-0.6	-0.4	1.8	-0.8	-0.4	-0.7	-0.3	-1.6	-0.7
Exposure to tobacco smoke at home	0.8	0.9	2.5	1.0	1.6	1.1	0.8	-0.6	1.4	0.5	1.0	-0.8	0.0	0.6	1.4	1.1	0.9	0.4	0.8
Pulse wave reflection index	0.8	1.0	6.1	1.0	-1.5	2.5	-0.1	-0.1	-0.9	1.2	-0.8	0.3	1.6	0.6	-0.4	-0.9	0.7	-0.2	0.0
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	3.5	-1.3	0.1	0.6	-0.2	-1.9	-0.2	-0.1	-0.7	-1.3	-0.8	-1.7	-0.7	-0.5	-1.2	-1.2	-1.4
Age at first live birth	0.8	1.3	6.4	0.8	-0.4	-0.0	1.5	2.5	0.8	-0.3	0.7	1.2	0.5	1.4	0.9	1.7	1.1	1.3	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.7	-0.8	-0.7	-0.6	-0.2	-1.7	-0.8	0.5	-0.5	-1.2	0.1	-1.3	-0.9	-0.2	-1.3	-1.0	-1.4
Eye problems/disorders: Cataract	0.8	0.9	3.3	0.2	0.4	0.8	0.3	0.8	-0.4	1.8	1.0	1.8	1.6	0.9	0.2	0.8	0.9	0.9	0.5
Medication for cholesterol	0.8	1.3	6.9	-0.1	-2.6	0.1	-1.6	0.8	-1.7	0.2	-1.1	0.6	0.9	-0.5	-1.4	-1.3	-0.9	-1.0	-0.7
Medication: Gliclazide	0.8	0.9	6.4	0.5	-0.3	0.5	-0.2	0.5	-0.4	2.5	1.2	1.4	1.3	1.3	0.4	0.3	1.0	0.8	0.3
Pain type(s) experienced in last month: Hip pain	0.8	1.1	2.7	1.1	1.6	-0.9	0.9	0.7	1.1	1.0	1.4	0.7	1.0	0.7	1.4	0.7	1.1	1.0	1.0
Ever depressed for a whole week	0.8	1.0	4.7	-0.8	-0.1	-2.2	-1.2	-1.0	-0.7	-0.8	-0.9	-1.1	-0.8	-0.9	-0.9	-0.9	-1.7	-0.4	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	5.6	0.4	1.1	1.3	-0.1	0.9	0.3	2.4	1.6	1.4	0.8	0.8	0.7	1.0	0.1	0.4	0.2
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.7	0.4	0.9	0.0	1.5	1.9	1.0	-1.3	0.7	0.3	-0.3	1.3	1.0	0.8	0.9	1.3	1.1
HbA1C	0.7	0.8	1.7	1.0	0.9	-1.3	1.1	0.6	1.1	-1.2	0.7	-0.7	0.3	0.5	1.0	1.0	0.7	1.0	1.0
Systolic Blood Pressure	0.7	3.4	9.4	0.7	3.1	-0.0	1.7	0.7	2.6	-1.5	2.2	0.3	-1.1	2.4	2.2	3.1	1.4	2.2	1.8
Mouth/teeth dental problems: Dentures	0.7	1.2	5.0	-0.4	-1.6	0.1	-2.2	-1.1	-1.0	1.2	-0.1	0.6	1.1	-0.4	-0.9	-1.7	-0.2	-1.6	-1.3
Standing height	0.7	7.2	13.0	-3.1	-3.2	-1.8	-1.8	-0.6	-2.9	-1.8	-3.5	-3.5	-0.4	-3.3	-3.4	-2.9	-3.6	-2.5	-3.2
Pulse wave peak to peak time	0.7	0.9	4.2	-1.0	0.7	-1.8	0.1	0.9	0.1	-1.4	0.3	0.1	-2.0	0.6	0.1	0.5	-0.1	1.5	0.5
Emphysema/chronic bronchitis	0.7	0.8	2.8	-0.9	0.5	-0.4	-1.3	-0.7	0.0	-0.9	-0.6	-1.2	-1.7	-1.1	-0.3	-0.9	-1.2	-0.7	-0.8
Myopia	0.7	1.0	3.6	0.2	0.6	-1.1	0.2	1.5	0.8	0.2	1.5	0.9	0.7	1.9	1.0	1.4	0.9	0.8	0.8
Verbal and Numeric Reasoning (VNR)	0.6	1.5	8.9	0.4	0.0	-1.1	0.7	3.0	0.1	0.1	2.0	1.7	1.9	1.2	0.5	0.8	0.8	0.1	0.8
Ovarian Cancer	0.6	0.8	5.1	-0.1	-2.3	-1.3	-1.1	-0.6	-1.0	1.0	-0.3	0.5	-0.1	-0.1	-0.8	-0.6	-0.1	-0.6	-0.8
Age at First Birth	0.6	0.9	4.2	0.2	-0.6	1.5	1.2	0.2	-0.3	2.0	0.7	0.9	2.1	-0.1	-0.0	0.9	0.5	-0.2	-0.2
Cardiovascular Disease	0.6	2.1	8.5	1.1	2.9	-0.3	1.8	-1.0	2.4	-0.5	1.9	-0.0	-1.4	0.6	2.1	1.9	1.1	0.5	1.1
Relative age of first facial hair	0.6	1.2	5.2	-0.7	-1.2	-2.3	-1.9	-0.4	-0.6	0.6	-1.2	-0.4	0.5	-0.8	-0.9	-1.7	-0.8	-1.2	-1.0
Supplements: Zinc	0.6	0.7	1.8	-1.1	0.6	-1.0	-0.3	-1.2	0.3	-0.8	-0.5	-1.3	-1.3	-1.2	-0.2	-0.3	-0.7	-0.4	-0.6
Multivitamins +/- minerals	0.6	0.7	2.8	-1.7	-0.5	-1.4	-0.6	-0.1	-0.8	1.2	0.0	1.4	0.4	-0.5	-0.9	-0.2	-0.4	0.1	-1.0
Weight	0.6	2.9	7.1	-2.0	-1.4	0.2	-0.7	-1.5	-1.6	0.5	-1.5	-2.5	-0.1	-2.7	-1.9	-1.6	-2.4	-2.2	-2.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.8	1.2	0.7	-0.1	1.1	-0.1	1.1	0.9	1.4	0.3	1.2	-0.0	1.0	1.1	0.9	-0.9	0.2
Medication: Lansoprazole	0.6	0.6	2.7	0.6	0.0	1.2	0.9	0.4	0.6	1.4	1.1	0.4	1.6	0.1	0.7	0.7	0.4	0.2	0.3
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.5	-0.6	-0.6	-1.3	-0.9	-0.4	-0.8	0.0	-0.8	-0.7	0.0	-1.1	-0.8	-1.9	-0.6	-0.9	-0.9
Blood clot in the leg (DVT)	0.6	0.8	2.8	0.2	0.9	-0.1	1.2	1.7	0.8	-1.3	0.5	0.3	-0.6	1.0	0.7	0.6	0.7	1.2	0.9
Exposure to tobacco smoke outside home	0.6	0.8	4.2	0.0	-0.0	-0.5	-0.9	-1.6	0.1	-0.6	-0.6	-2.0	-1.2	-0.7	-0.1	-0.6	-0.8	-1.0	-0.9
Wheeze or whistling in the chest in last year	0.6	1.1	7.2	0.4	-0.2	0.6	0.1	-0.6	-0.4	2.7	0.3	-0.2	1.9	-1.2	-0.0	-0.8	-0.1	-2.0	-0.8
Medication: Omeprazole	0.6	0.8	2.9	0.5	0.8	1.7	-0.2	1.1	0.4	1.3	1.3	1.1	0.2	1.1	0.6	1.0	-0.0	0.6	0.3
Mean time to correctly identify matches	0.6	1.2	6.0	0.2	-1.6	1.8	-0.5	1.6	-0.6	1.3	0.3	1.8	2.4	0.8	-0.2	-0.3	0.4	-0.2	-0.2
Pulse rate, automated reading	0.6	2.1	13.8	-1.1	0.5	0.1	-1.4	0.8	-0.2	3.7	2.5	2.3	1.3	0.4	-0.0	0.1	-0.3	-1.6	-0.9
Chest pain or discomfort	0.6	0.9	5.0	-0.1	-1.2	0.3	-0.5	-1.2	-0.5	0.8	-0.0	-1.0	0.6	-1.2	-0.5	-0.6	-0.9	-2.2	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	6.1	0.9	-0.0	2.5	0.8	2.0	0.4	0.2	0.6	0.7	0.7	1.7	0.7	1.0	1.0	1.5	1.2
Commuting to job workplace: Walk	0.6	0.6	2.2	0.2	0.9	0.1	1.1	1.5	1.2	-0.4	0.4	0.4	-0.1	0.5	0.9	0.5	0.5	1.1	1.2
Osteoarthritis (self-reported)	0.6	0.8	4.1	0.6	0.9	2.0	0.4	0.3	0.6	1.1	1.5	0.1	0.8	1.0	1.0	0.8	0.7	0.6	0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.6	-0.2	1.7	-1.0	0.9	-0.4	1.2	-1.9	-0.1	-0.7	-0.8	-0.2	0.7	0.5	0.2	1.2	0.5
Average weekly beer plus cider intake	0.6	0.9	4.2	1.1	0.7	2.0	0.7	0.1	1.1	1.2	1.3	-0.0	0.7	0.8	1.1	1.2	0.9	0.2	0.7
Commuting to job workplace: Cycle	0.6	0.7	4.5	0.9	-0.2	-2.1	1.4	0.1	0.2	1.1	-0.2	-0.6	1.4	-0.3	0.5	0.2	0.6	0.5	0.5
Breast Cancer	0.5	1.2	6.2	-0.6	-0.7	-0.1	-1.0	-2.5	-1.1	0.6	-0.7	-1.0	-1.2	-1.3	-0.9	-0.6	-1.2	-1.2	-1.2
Blood Platelet Count	0.5	5.4	14.4	2.9	3.1	1.4	2.7	0.3	2.6	-0.6	2.2	0.5	-1.5	2.6	2.7	3.8	2.1	3.0	2.9
Height	0.5	10.2	18.3	-3.1	-4.3	-1.3	-3.1	-0.9	-4.1	0.0	-4.0	-2.3	1.3	-3.9	-4.1	-3.8	-4.1	-3.6	-4.0
Number of treatments/medications taken	0.5	1.0	4.1	-0.9	0.1	-0.9	-0.8	-2.0	-0.4	0.7	-0.6	-1.4	-0.8	-1.2	-0.4	-1.4	-0.9	-0.7	-1.4
Angina	0.5	0.7	2.7	0.8	0.8	-0.4	1.6	0.3	1.4	0.4	1.2	0.5	0.2	0.3	1.2	1.0	0.8	0.1	0.8
Medication for hormone replacement therapy	0.5	0.6	3.2	0.2	1.0	-0.5	0.3	-1.5	0.5	-0.7	-0.8	-1.8	-0.8	-0.8	0.3	-0.0	-0.2	0.0	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.8	0.9	1.4	0.2	1.7	0.9	1.4	0.1	0.6	0.9	-0.6	0.7	1.3	1.5	1.0	1.4	1.4
Impedance of leg (left)	0.5	2.3	5.5	1.5	1.4	0.2	0.7	1.1	2.2	-0.7	1.6	1.0	-0.0	2.4	2.0	2.1	1.8	1.7	2.0
Diabetes (self-reported)	0.5	0.8	1.7	-1.0	-1.0	-0.5	-1.2	-0.7	-1.3	0.5	-1.0	-0.6	-1.1	-0.2	-1.1	-1.1	-1.0	0.0	-1.1
Happiness	0.5	0.6	1.8	-1.1	-0.8	-1.2	-0.0	-0.3	-0.2	-0.9	-0.5	-1.3	0.0	-1.0	-0.6	-0.3	-1.1	-1.0	-1.1
Illnesses of mother	0.5	0.6	3.9	0.0	-0.6	-0.1	0.2	0.5	-0.9	2.0	0.7	1.3	1.2	0.4	-0.3	-0.2	0.5	0.4	-0.0
Glaucoma (self-reported)	0.5	0.6	1.2	1.1	1.1	0.1	0.8	-0.1	0.7	1.0	1.0	0.8	0.6	0.4	1.0	0.8	0.8	-0.2	0.6
Worry too long after embarrassment	0.5	0.9	2.7	0.4	-1.3	-1.4	-0.9	0.1	-1.7	0.5	-1.1	0.6	1.3	-0.4	-1.0	-1.6	-0.2	-0.5	-0.5
Number of children fathered	0.5	0.6	2.1	-0.4	0.8	-0.7	0.2	-1.4	0.4	-1.1	-0.5	-1.5	-0.4	-1.2	-0.1	-0.2	-0.4	-1.0	-0.5
Medication for pain relief, constipation, heartburn	0.5	0.9	4.3	0.3	0.2	0.1	0.9	2.1	0.7	-0.9	0.2	0.6	0.8	1.2	0.7	0.7	0.9	1.4	1.5
Medication: Blood pressure	0.5	0.8	3.1	-0.4	0.3	-0.7	-0.4	-1.8	-0.1	-0.5	-0.8	-1.7	-1.7	-0.9	-0.3	-0.5	-1.0	-0.7	-0.8
Medication: Ibuprofen	0.5	0.6	2.0	1.4	0.7	-0.4	0.8	0.4	0.7	0.7	1.3	0.5	0.9	0.4	0.9	0.9	1.1	-0.4	0.4
Medication: Seretide 50 evohaler	0.5	0.5	2.0	0.5	1.4	1.1	0.4	-0.3	0.8	-1.1	-0.0	-1.2	-1.1	-0.0	0.7	0.5	-0.1	-0.2	0.3
Alcohol intake frequency.	0.5	1.2	11.7	1.3	0.8	3.4	0.9	-1.3	0.9	0.4	-0.0	-1.0	-0.4	0.2	0.7	0.5	0.5	0.5	0.6
Had major operations	0.5	0.6	2.9	-0.3	-0.3	1.1	-0.2	-1.3	0.2	-0.9	-0.6	-1.7	-0.9	-0.6	-0.1	-0.5	-0.4	-0.7	-0.5
Age at last live birth	0.5	0.7	3.2	0.7	-0.7	0.5	0.3	1.8	0.2	0.2	0.6	1.4	0.9	1.4	0.4	1.1	0.6	0.7	0.8
Smoking status: Previous	0.5	0.7	2.4	-0.6	-0.4	-0.9	-0.9	-0.7	-0.1	1.4	0.1	0.1	1.2	-1.2	-0.3	-0.7	-0.3	-1.5	-1.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.8	0.7	0.8	0.5	0.8	-0.2	0.7	-1.5	-0.3	-0.7	-1.7	0.5	0.7	0.1	0.3	0.8	1.0
Mother’s age at death	0.5	0.6	2.3	0.1	1.5	0.2	0.2	0.5	0.9	-1.3	0.3	-0.1	-1.1	0.4	0.7	0.9	0.5	1.3	1.0
Eye problems/disorders: Glaucoma	0.5	0.6	1.8	0.8	1.4	0.1	1.0	-0.2	1.0	0.2	1.2	0.2	0.0	0.6	1.2	1.0	0.9	0.1	0.5
Medication: Bendroflumethiazide	0.5	0.7	3.1	-0.7	1.5	-1.8	0.1	-0.7	0.4	-0.6	-0.4	-1.3	-1.8	-0.4	0.1	0.1	-0.2	0.8	-0.1
Alzheimer’s Disease (in father)	0.4	0.4	1.2	0.1	-0.9	-0.7	-0.6	-1.1	-0.5	-0.4	-0.5	-0.3	-0.7	-0.6	-0.5	-0.8	-0.5	-1.0	-0.5
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.0	0.2	1.2	-0.5	0.4	-1.4	1.3	-0.1	0.5	-1.3	-0.5	-0.6	0.9	0.2	0.2	-0.0	-0.0
Ever had hysterectomy (womb removed)	0.4	0.4	1.0	-0.4	-0.5	0.6	-0.4	-1.0	-0.5	1.0	-0.1	-0.2	0.8	-0.8	-0.5	-0.8	-0.4	-0.8	-0.9
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	2.2	0.4	0.0	1.5	-0.3	0.2	-0.4	1.2	0.4	0.9	0.3	1.0	0.0	-0.0	0.5	0.6	0.4
Impedance of leg (right)	0.4	2.0	6.0	1.3	1.0	-0.3	0.3	1.2	1.6	0.0	1.7	1.5	0.5	2.4	1.7	1.9	1.8	1.8	1.7
Chronic bronchitis/emphysema (father)	0.4	0.4	1.2	-0.7	-0.1	0.1	-1.0	-0.6	-0.0	-1.1	-0.3	-1.1	-0.6	-0.6	-0.2	-0.7	-0.9	-0.8	-0.5
Had other major operations	0.4	0.5	4.1	-0.8	2.0	0.3	-0.4	-0.4	0.7	0.8	0.7	-0.2	-0.3	-0.6	0.4	0.4	0.0	-0.5	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.4	0.6	0.8	0.7	1.8	0.1	1.0	0.8	0.5	0.7	-0.2	0.5	1.0	1.3	1.2	1.5	1.1
Pain all over the body in last month	0.4	0.4	1.9	-0.6	-0.1	1.2	0.3	-1.4	-0.4	-0.1	-0.9	-0.8	-0.1	-0.9	-0.5	-0.5	-0.6	-0.1	-0.6
Medication: Ramipril	0.4	0.5	2.8	0.2	0.5	-1.7	0.4	-0.7	0.3	0.7	-0.1	-0.2	-0.4	0.2	0.5	-0.1	0.8	1.6	0.5
Fluid intelligence score	0.4	0.8	6.1	-0.2	-0.7	-0.9	0.3	2.5	-0.9	0.1	1.0	1.1	1.2	0.7	-0.4	0.4	0.1	0.1	0.2
Hip circumference	0.4	1.6	4.9	-1.3	-1.1	-0.1	-0.4	-1.4	-1.5	0.5	-1.3	-1.4	-0.1	-2.2	-1.6	-1.5	-1.5	-1.3	-1.7
Noisy workplace	0.4	0.5	2.8	0.2	1.0	-1.7	0.4	-1.5	0.6	-0.3	-0.4	-0.7	-0.9	-0.9	0.3	-0.3	0.0	-0.2	-0.1
Qualifications: A levels/AS levels or equivalent	0.4	0.8	6.4	0.1	0.2	0.6	1.5	2.5	-0.0	-1.0	0.0	0.3	1.2	0.6	0.2	0.4	0.6	1.0	0.8
Hair/balding pattern: Pattern 4	0.4	0.9	2.2	1.0	1.3	-0.1	0.6	0.8	1.5	-0.6	1.2	0.7	0.1	1.2	1.3	0.9	1.0	0.7	1.0
Peak expiratory flow (PEF)	0.4	1.0	3.5	0.3	1.2	-0.8	0.1	1.1	1.4	0.2	0.7	-0.2	-1.1	1.5	1.2	0.6	0.9	1.9	1.2
Angina (self-reported)	0.4	0.6	2.4	0.7	0.9	-0.0	1.6	-0.1	1.4	0.3	1.0	0.2	0.1	0.0	1.1	0.8	0.7	-0.0	0.7
Migraine (self-reported)	0.4	0.5	2.3	0.7	-0.6	1.5	0.4	-1.4	0.0	0.4	-0.3	0.1	0.8	-1.0	-0.1	-0.3	-0.1	-1.4	-0.4
Number of full sisters	0.4	0.5	1.6	0.0	-0.5	0.8	-0.9	0.8	-0.3	0.6	0.9	0.8	1.3	0.6	-0.2	-0.2	-0.1	-1.2	-0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	4.8	-0.3	-0.3	-2.2	-0.0	1.1	-0.1	-1.1	0.3	-0.2	-0.2	0.5	0.1	-0.0	0.1	0.8	0.4
Illnesses of father: Heart disease	0.4	0.6	2.0	1.0	-0.0	1.4	0.1	-1.3	0.7	-0.7	-0.6	-1.4	-1.2	-0.4	0.5	-0.2	0.0	-0.6	0.3
Hearing aid user	0.4	0.5	2.8	0.7	-0.9	0.9	-0.6	-1.0	0.1	0.0	-0.3	-0.5	0.9	-0.2	0.0	-0.4	-0.4	-1.7	-0.4
Cholesterol lowering medication	0.4	0.6	1.9	0.2	1.3	-1.0	1.1	-1.0	1.4	0.2	1.0	-0.5	-0.3	0.3	1.0	0.8	0.7	-0.2	0.3
Coronary Artery Disease (CAD)	0.3	0.4	3.1	0.7	0.4	1.7	0.9	-0.9	-0.3	0.1	-0.7	-0.2	0.2	-0.7	-0.2	0.2	-0.1	0.4	0.2
Fasting Glucose	0.3	0.3	2.1	-0.4	0.5	-0.9	-0.1	0.1	-0.0	-1.5	-0.2	-0.5	-1.3	0.1	-0.2	-0.2	-0.3	0.5	0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.0	-0.7	0.1	-0.2	-0.8	-0.2	-0.9	0.1	-0.3	-0.0	-0.3	-0.6	-0.8	-0.6	-1.0	-0.2	-0.9
Blood White Count	0.3	2.0	7.1	-1.5	-0.3	-0.4	-0.9	-2.7	-0.5	-0.4	-0.7	-2.7	-1.8	-1.7	-0.8	-1.0	-1.9	-1.4	-1.6
Pack years adult smoking proportion	0.3	0.4	2.9	-0.7	0.0	0.2	0.0	0.1	0.7	-0.3	0.8	-1.0	-0.9	-0.2	0.2	0.2	-0.4	-1.7	-0.8
Supplements: Glucosamine	0.3	0.4	1.7	-0.3	0.6	-1.3	-0.7	-0.6	-0.6	0.5	-0.4	-0.2	-0.3	-0.0	-0.1	-0.6	0.6	1.3	-0.0
Sitting height	0.3	2.2	6.1	-2.3	-1.1	-1.1	-0.3	0.6	-0.9	-2.5	-1.8	-2.1	-1.3	-1.4	-1.6	-1.2	-2.2	-0.6	-1.3
Waist circumference	0.3	1.3	3.2	-1.0	-0.6	-0.0	-0.4	-1.6	-0.8	1.5	-0.4	-1.3	0.4	-1.8	-0.9	-0.9	-1.2	-1.8	-1.8
Medication: Simvastatin	0.3	0.5	2.5	1.3	0.4	-0.8	1.6	-1.1	0.6	-0.3	-0.2	-0.8	-0.3	-0.2	0.6	0.0	0.3	0.0	0.6
Birth weight	0.3	0.6	2.3	-0.8	-0.9	-1.5	0.5	1.1	-0.6	-0.5	-0.5	-0.2	1.2	-0.8	-0.7	-0.7	-0.7	-0.7	-0.5
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.0	-0.4	1.2	0.5	-0.2	0.4	0.3	0.9	1.0	1.4	0.4	0.0	0.3	-0.1	0.4	0.1	0.1
Comparative body size at age 10	0.3	0.9	2.3	1.1	1.5	0.2	1.5	-0.1	1.0	1.5	0.7	0.7	0.7	-0.3	1.0	1.1	1.1	0.4	0.9
Shortness of breath walking on level ground	0.3	0.4	1.3	-0.8	-0.0	1.1	-0.9	-0.6	0.4	0.8	0.3	-0.4	-0.6	-0.2	0.0	0.1	-0.5	-1.1	-0.8
Medication: Allopurinol	0.3	0.4	2.6	0.3	0.1	0.7	-0.1	1.6	0.6	0.1	0.7	0.7	0.0	0.9	0.6	0.3	0.5	0.7	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	-0.6	-0.8	-0.1	-1.0	-0.8	-0.7	0.1	-0.8	-0.7	-1.0	-0.1	-0.7	-0.8	-0.3	0.8	-0.2
Medication: Aspirin	0.3	0.4	1.4	-0.5	-0.3	-1.2	-0.9	-0.5	-0.8	-0.4	-0.4	-0.6	-0.1	-0.2	-0.6	-0.8	-0.7	0.0	-0.5
Supplements: Vitamin C	0.3	0.4	1.0	0.6	1.0	0.9	-0.0	0.6	0.8	-0.7	-0.1	-0.2	-0.3	0.6	0.8	0.5	0.6	0.8	0.7
Ever had bowel cancer screening	0.3	0.3	1.6	-0.8	0.5	-0.5	-0.3	-0.4	-0.0	-1.1	-0.4	-0.5	-1.2	-0.2	-0.3	-0.2	-1.0	0.0	-0.3
Mineral and other dietary supplements	0.3	0.4	2.4	0.4	-1.1	1.5	-0.2	0.8	-0.4	0.9	0.1	0.4	0.4	0.2	-0.2	-0.2	-0.1	-1.0	-0.2
Breast cancer (self-reported)	0.3	0.3	1.6	-0.0	0.1	-0.7	-0.4	-0.8	0.3	0.9	0.0	0.1	1.1	-0.4	0.2	-0.4	0.1	-1.3	-0.6
Medication: Aspirin	0.3	0.4	1.4	-0.4	-0.6	-1.2	-0.7	-0.6	-0.8	-0.2	-0.6	-1.0	0.3	-0.3	-0.6	-0.9	-0.7	-0.1	-0.6
Number of self-reported non-cancer illnesses	0.3	0.6	1.9	0.5	1.4	-0.4	0.1	-1.2	1.1	1.2	1.2	-0.4	0.4	-0.2	0.9	0.3	-0.0	-0.6	-0.2
Average weekly champagne plus white wine intake	0.3	0.4	2.0	-0.3	-1.0	-1.3	0.3	1.4	0.1	-0.7	-0.1	-0.3	0.4	0.9	-0.1	0.4	0.2	0.7	0.4
Medication: Lisinopril	0.3	0.4	0.9	0.1	-0.1	0.2	-0.6	-0.9	-0.9	0.8	-0.5	-0.4	0.0	-0.9	-0.6	-0.8	-0.7	-0.9	-0.6
Vascular/heart problems diagnosed by doctor	0.3	0.7	4.3	0.3	-2.1	0.8	-0.6	0.7	-1.2	0.6	-0.9	0.3	1.4	-0.0	-0.8	-0.8	0.0	-0.5	-0.2
Basal cell carcinoma (self-reported)	0.3	0.3	1.7	-0.7	-0.8	-0.7	-0.3	-0.1	-0.7	1.3	0.1	0.3	0.4	0.4	-0.5	-0.5	0.1	0.4	-0.5
Heart disease (siblings)	0.3	0.4	1.8	-0.2	-1.2	-1.3	-0.6	-0.1	-0.4	0.7	-0.2	-0.3	0.5	0.2	-0.5	-0.4	-0.6	-1.0	-0.5
Pack years of smoking	0.3	0.4	1.7	-0.4	0.5	0.4	0.3	0.3	1.1	-0.3	1.1	-0.9	-1.0	0.2	0.6	0.6	-0.1	-1.3	-0.4
Prostate Cancer	0.2	0.3	1.3	0.1	-1.1	0.7	-0.6	0.1	-0.8	-0.4	-0.4	-0.1	0.0	0.1	-0.6	-0.5	-0.2	-0.5	-0.5
Body Mass Index (BMI) (2010)	0.2	0.3	0.8	0.5	-0.8	0.4	-0.4	0.2	-0.8	0.8	-0.3	0.7	0.9	-0.0	-0.4	-0.5	0.2	0.6	0.4
Blood Eosinophil Count	0.2	1.4	3.0	-1.3	-0.7	-0.5	-0.4	-1.7	-0.9	-0.7	-1.1	-1.7	-0.7	-1.5	-1.2	-1.1	-1.5	-1.7	-1.6
Waist Hip Ratio (WHR)	0.2	0.7	2.4	0.6	-0.1	-1.0	0.2	-1.2	0.9	1.6	1.1	-0.3	0.7	0.2	0.9	0.8	0.5	-1.4	-0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.9	0.1	-0.8	-1.2	-0.5	-0.4	-1.4	0.7	-0.5	-0.1	-0.5	0.1	-0.7	-0.6	-0.1	0.5	-0.3
Lung FEV1/FVC ratio	0.2	1.1	4.5	-0.2	1.5	-0.5	1.3	-0.1	2.1	-1.4	0.8	-1.2	-0.6	0.6	1.4	1.1	0.2	0.8	0.8
Vitamin and mineral supplements	0.2	0.3	1.6	1.2	-0.3	1.3	0.4	-0.1	-0.0	-0.2	0.1	-0.8	-0.2	0.5	0.2	0.3	0.2	-0.3	0.6
Trunk fat percentage	0.2	0.7	4.6	-0.1	0.6	2.2	0.5	0.1	0.4	1.5	0.9	-0.1	1.2	0.1	0.3	1.1	0.1	-0.0	-0.2
Relative age voice broke	0.2	0.4	2.3	-0.1	-0.8	-1.5	-0.7	-0.5	0.1	0.7	-0.7	0.5	-0.2	0.0	-0.1	-1.0	0.2	-0.1	-0.2
Taking other prescription medications	0.2	0.3	1.8	-0.2	1.3	0.8	-0.0	-0.7	0.4	1.1	0.4	-0.0	-0.4	0.2	0.3	-0.3	0.3	0.6	-0.1
High blood pressure	0.2	0.6	3.7	-0.5	1.9	-1.0	0.4	-0.9	1.0	-0.3	0.8	-0.2	-1.5	-0.2	0.6	0.6	-0.0	0.2	-0.1
Body mass index (BMI)	0.2	0.8	1.8	-0.9	-0.1	1.0	-0.0	-1.4	-0.5	1.3	-0.1	-1.0	-0.0	-1.4	-0.6	-0.4	-1.0	-1.2	-1.3
Hearing difficulty/problems with background noise	0.2	0.3	1.5	0.8	0.4	-1.2	-0.1	0.7	0.3	-0.6	-0.3	-0.2	0.0	0.6	0.4	-0.5	0.4	0.6	0.5
Hair/balding pattern: Pattern 2	0.2	0.2	0.8	-0.6	-0.4	-0.5	0.2	0.2	-0.9	0.5	-0.3	0.5	0.1	-0.1	-0.6	-0.5	-0.5	-0.3	-0.5
Had menopause	0.2	0.2	2.2	-0.2	0.1	1.5	-0.0	-0.3	-0.4	0.2	0.1	-0.4	0.8	0.0	-0.3	-0.4	0.0	0.0	-0.3
Heart attack	0.2	0.2	0.9	0.5	-0.2	0.9	0.1	-0.7	0.3	-0.7	-0.6	-0.6	-0.2	0.2	0.2	-0.3	-0.0	0.3	0.3
Number of live births	0.2	0.3	2.2	0.9	-0.1	0.7	-0.3	-0.8	-0.3	1.5	0.1	0.3	0.7	-0.0	0.1	-0.7	0.2	-0.3	-0.0
Arm fat mass (right)	0.2	0.9	2.3	-1.2	-0.5	1.0	-0.2	-1.1	-0.9	1.1	-0.4	-1.2	0.5	-1.4	-1.0	-0.6	-1.1	-1.1	-1.5
Breastfed as a baby	0.2	0.2	0.8	-0.3	0.8	0.4	-0.1	0.4	-0.1	0.6	-0.2	0.4	-0.6	0.6	-0.0	0.1	0.3	0.9	0.2
Tense / ‘highly strung’	0.2	0.3	1.7	0.4	0.2	-1.3	0.1	-0.6	-0.5	-0.3	-0.4	-0.5	-1.2	0.3	-0.2	0.1	-0.1	1.1	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.5	-0.9	-1.2	-0.0	-0.7	0.9	-0.9	-0.3	-0.6	0.5	0.3	-0.0	-0.9	-0.7	-0.1	0.2	-0.3
Gout (self-reported)	0.2	0.3	0.7	0.8	0.1	0.6	0.5	0.5	0.9	-0.0	0.2	-0.3	0.1	0.4	0.7	0.8	0.2	0.7	0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.6	0.2	-0.4	-0.6	-0.1	-0.6	-0.3	1.3	0.1	1.0	0.4	-0.6	-0.2	-0.1	0.1	-0.8	-0.4
Body fat percentage	0.2	0.7	3.4	0.1	0.8	1.8	0.6	-0.2	0.5	1.6	1.0	-0.1	1.1	0.1	0.5	1.1	0.2	-0.0	-0.1
Number of full brothers	0.2	0.2	1.0	0.3	-0.5	0.4	-0.8	-0.6	-0.4	1.0	-0.1	0.7	0.2	0.1	-0.3	-0.5	0.1	-0.4	-0.3
Leg fat mass (right)	0.2	0.9	2.6	-1.1	-0.7	0.5	-0.2	-1.2	-0.8	1.0	-0.3	-1.1	0.2	-1.4	-1.0	-0.7	-1.2	-1.5	-1.6
Comparative height size at age 10	0.2	1.2	3.6	-1.2	-1.3	0.3	-0.8	0.3	-1.6	-0.6	-1.4	-1.9	-0.3	-0.9	-1.5	-0.9	-1.6	0.2	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.3	0.6	0.3	0.4	-0.8	-0.2	-0.4	1.1	0.2	0.7	0.3	0.7	-0.0	-0.5	0.4	0.9	0.2
Hypertension (Self-reported)	0.2	0.7	4.1	-1.0	1.3	-1.0	0.1	-1.4	0.4	-0.5	0.1	-0.7	-2.0	-0.5	0.0	-0.0	-0.5	0.1	-0.5
Arm fat percentage (left)	0.2	0.6	3.2	0.3	0.8	1.5	0.7	-0.3	0.5	1.8	0.9	-0.0	1.1	0.1	0.5	0.9	0.4	0.1	-0.0
Friendships satisfaction	0.2	0.3	1.8	0.1	-0.1	-0.4	1.1	0.1	0.7	-1.4	0.6	-0.3	-0.0	0.0	0.4	0.6	0.1	-0.4	0.2
Qualifications: nursing, teaching	0.2	0.2	1.1	0.0	-0.1	0.8	0.5	1.1	0.4	0.3	0.2	0.1	0.3	0.1	0.4	0.8	0.1	0.7	0.6
Arm fat mass (left)	0.2	0.7	1.9	-1.1	-0.4	0.8	-0.1	-0.8	-0.7	1.3	-0.2	-1.1	0.6	-1.1	-0.8	-0.4	-1.0	-1.0	-1.4
Tinnitus: Yes, now most or all of the time	0.2	0.3	2.0	-0.1	0.2	-0.8	0.4	0.7	0.6	-1.4	-0.4	-0.1	0.3	0.5	0.1	0.5	-0.4	-0.0	0.1
Medication: Blood pressure	0.2	0.3	1.9	-0.8	1.4	-0.3	0.4	-0.7	0.4	0.6	0.7	0.5	-0.5	-0.2	0.2	-0.1	0.2	0.2	-0.2
Diastolic blood pressure, automated reading	0.2	0.7	2.1	-1.4	1.3	-0.2	-0.0	1.0	0.6	-1.0	1.2	0.0	-1.0	0.5	0.2	1.5	-0.6	0.5	-0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	0.3	-0.4	0.9	-0.0	-0.7	0.3	-0.7	-0.7	-0.7	-0.3	0.1	0.1	-0.3	-0.1	0.2	0.2
Alcohol drinker status: Previous	0.2	0.3	1.5	0.5	0.8	1.2	0.6	0.6	0.6	0.0	-0.1	0.5	0.3	0.1	0.6	-0.1	0.5	0.0	0.4
Leg fat mass (left)	0.2	0.9	2.6	-1.0	-0.5	0.4	0.1	-1.3	-0.6	0.8	-0.3	-1.3	0.2	-1.5	-0.8	-0.5	-1.2	-1.6	-1.5
Heel T-Score	0.1	1.1	4.2	-1.3	1.0	-2.0	1.2	-1.8	1.2	0.8	0.1	0.0	-0.1	-1.8	0.4	0.3	-0.0	-1.0	-0.6
BMI	0.1	0.4	3.0	0.1	-0.0	1.7	0.9	0.4	-0.3	1.2	0.3	-0.5	0.5	-0.3	-0.1	0.1	-0.2	-0.3	-0.3
Hypothyroidism (self reported)	0.1	0.1	0.6	-0.2	0.5	0.8	-0.1	0.4	0.2	-0.2	0.5	0.4	-0.3	0.4	0.2	-0.3	0.0	0.2	0.2
Hair Pigment	0.1	4.1	12.6	-1.9	-1.9	0.1	-2.1	-2.6	-2.3	0.9	-1.1	-0.9	0.6	-2.6	-2.4	-2.0	-2.0	-3.5	-3.1
Tanning	0.1	1.7	7.7	-1.1	0.6	-1.7	0.2	-1.2	0.9	-2.8	-0.7	-2.2	-2.5	0.0	0.4	-0.1	-0.0	1.6	0.3
Hand grip strength (left)	0.1	0.2	0.8	0.2	0.5	0.1	0.8	0.9	0.6	0.0	0.1	0.4	-0.8	0.3	0.3	0.2	0.3	0.3	0.6
Hand grip strength (right)	0.1	0.2	1.4	-0.4	0.8	-1.2	0.1	0.8	0.6	0.3	0.3	0.4	-0.8	-0.1	0.1	0.3	-0.1	0.1	0.1
Qualifications: CSEs or equivalent	0.1	0.2	0.9	0.4	-0.3	-0.6	-0.1	-0.9	-0.1	0.7	-0.5	-0.2	0.2	-0.5	-0.1	-0.5	0.1	-0.2	-0.2
Serious illness, injury or assault to yourself	0.1	0.1	0.3	-0.5	0.1	0.3	0.3	-0.2	0.4	0.2	-0.1	-0.6	0.1	-0.3	0.2	0.3	0.1	0.5	-0.1
Medication: Atenolol	0.1	0.1	0.5	-0.4	0.3	-0.5	0.2	-0.1	0.4	0.3	0.4	0.7	-0.5	0.4	0.3	0.1	0.3	0.3	0.1
Medication: Levothyroxine sodium	0.1	0.1	0.5	-0.4	0.0	0.5	-0.1	-0.2	-0.3	0.7	0.4	0.4	0.5	0.1	-0.1	-0.2	-0.1	-0.2	-0.3
Trunk fat mass	0.1	0.6	1.7	-0.9	-0.2	1.3	0.1	-0.5	-0.5	1.1	-0.1	-1.0	0.8	-1.0	-0.6	0.1	-0.9	-0.9	-1.2
Illnesses of siblings	0.1	0.2	0.9	0.3	-0.4	0.7	0.2	-0.5	-0.4	-1.0	-0.6	0.4	0.4	-0.6	-0.3	-0.3	0.1	-0.1	-0.1
Arm fat percentage (right)	0.1	0.5	2.8	0.2	0.8	1.7	0.8	-0.2	0.4	1.4	0.8	-0.1	1.0	0.1	0.4	0.9	0.3	0.3	-0.0
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	0.3	-0.1	-0.1	0.4	-0.4	-0.0	-0.1	-0.1	-0.3	0.7	-0.8	-0.0	0.3	-0.1	-0.5	-0.0
Headache pain in last month	0.1	0.2	0.9	0.1	-0.2	-0.2	0.6	-0.7	0.7	-0.4	0.1	-0.9	0.0	-0.5	0.3	-0.2	-0.0	-0.5	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.8	-0.7	-0.3	0.9	-0.2	0.2	-0.4	0.8	0.3	0.2	0.3	-0.2	-0.3	-0.6	-0.4	-0.2	-0.5
Leg fat percentage (right)	0.1	0.3	1.6	-0.3	0.3	0.6	0.4	-1.3	0.4	1.1	0.6	-0.4	0.1	-0.4	0.2	0.5	-0.2	-0.6	-0.6
Whole body fat mass	0.1	0.6	1.5	-0.9	-0.2	1.0	0.1	-0.6	-0.5	1.2	0.0	-1.1	0.7	-1.0	-0.6	-0.0	-0.9	-1.0	-1.2
Diabetes diagnosed by doctor	0.1	0.1	0.7	0.0	0.1	0.3	-0.2	0.2	-0.3	0.8	0.3	0.4	-0.3	0.7	0.0	0.0	0.1	0.5	-0.1
Osteoporosis (self-reported)	0.1	0.2	0.6	0.3	0.8	0.4	0.1	-0.1	0.6	0.0	0.5	-0.1	0.4	0.2	0.5	0.6	0.6	0.4	0.3
Leg fat percentage (left)	0.1	0.5	1.9	-0.1	0.7	0.8	0.8	-1.4	0.8	0.6	0.6	-0.8	-0.2	-0.6	0.4	0.8	-0.2	-0.6	-0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.9	-0.5	0.9	-0.9	-0.1	0.0	-0.0	-0.4	0.1	-0.1	-0.0	-0.1	0.1	-0.3	0.0	-0.2	-0.3

Hub : Genes

CD40

Models

Trait associations