[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr20:61,522,825-62,912,463

Best TWAS P=2.92e-15 · Best GWAS P=2.67e-13 conditioned to 0.00374

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Brain Cerebellar Hemisphere	STMN3	0.39	0.08	lasso	5	0.22	2.1e-06	-6.3	-7.9	2.9e-15	0.65	0.19	0.53	TRUE
23	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	-6.1	-7.7	1.9e-14	0.88	0.01	0.80	FALSE
17	YFS	Blood	LIME1	0.12	0.19	enet	15	0.19	5.3e-59	-7.1	-7.4	1.1e-13	0.98	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNFRSF6B	0.05	0.02	blup	44	0.03	2.9e-03	-7.3	-7.3	2.5e-13	0.93	0.01	0.75	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ARFRP1	0.07	0.07	lasso	3	0.06	5.3e-08	-7.2	7.3	3.9e-13	-0.96	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARFRP1	0.03	0.02	lasso	2	0.02	1.2e-03	-7.2	7.2	5.0e-13	-0.98	0.01	0.97	FALSE
4	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	-5.9	-7.2	5.9e-13	0.66	0.04	0.95	FALSE
10	GTEx	Testis	RTEL1	0.19	0.06	lasso	5	0.14	8.0e-07	-6.2	-7.1	9.8e-13	0.62	0.17	0.66	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	-6.1	-7.1	1.4e-12	0.93	0.02	0.89	FALSE
5	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	-6.2	-6.8	7.6e-12	0.73	0.12	0.61	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	LIME1	0.04	0.05	blup	47	0.05	9.0e-06	-7.3	-6.8	1.0e-11	0.97	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	ARFRP1	0.04	0.00	blup	51	0.00	1.3e-01	-7.1	6.8	1.4e-11	-0.81	0.01	0.58	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	-6.3	6.8	1.5e-11	-0.83	0.05	0.95	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC2A4RG	0.05	0.01	blup	48	0.02	2.0e-03	-7.3	6.7	2.2e-11	-0.85	0.01	0.95	FALSE
15	METSIM	Adipose	STMN3	0.20	0.08	enet	30	0.11	1.0e-16	-6.2	6.7	2.9e-11	-0.43	0.91	0.09	FALSE
29	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LIME1	0.10	0.02	blup	47	0.04	1.5e-02	-7.3	-6.6	3.2e-11	0.90	0.01	0.64	FALSE
12	GTEx	Whole Blood	STMN3	0.10	0.00	lasso	3	0.00	1.2e-01	-6.5	6.5	5.8e-11	-0.73	0.02	0.81	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	-6.2	-6.3	2.7e-10	0.84	0.04	0.50	FALSE
2	CommonMind	Brain Pre-frontal Cortex	STMN3	0.07	0.02	lasso	4	0.05	2.8e-06	-6.3	-6.3	3.0e-10	0.71	0.03	0.97	FALSE
9	GTEx	Pituitary	STMN3	0.43	0.00	enet	8	0.06	1.1e-02	-3.1	-6.3	3.5e-10	0.55	0.05	0.32	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	-6.0	-6.1	1.4e-09	0.81	0.05	0.94	FALSE
7	GTEx	Cells Transformed fibroblasts	CTD-3184A7.4	0.09	0.00	enet	28	0.00	1.4e-01	-5.1	-6.0	1.5e-09	0.49	0.02	0.87	FALSE
16	METSIM	Adipose	TPD52L2	0.03	0.00	bslmm	207	0.02	1.5e-03	3.3	5.9	2.9e-09	-0.68	0.02	0.75	FALSE
14	METSIM	Adipose	RTEL1	0.07	0.01	enet	15	0.03	9.2e-06	-6.7	5.9	3.2e-09	-0.44	0.08	0.90	FALSE
6	GTEx	Breast Mammary Tissue (Female)	GMEB2	0.36	0.06	lasso	4	0.05	1.2e-02	-6.4	-5.9	3.7e-09	0.61	0.15	0.10	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A4RG	0.03	0.01	blup	48	0.02	2.4e-03	-6.1	5.8	8.2e-09	-0.69	0.06	0.50	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	STMN3	0.02	0.02	blup	43	0.02	1.7e-03	-6.2	-5.7	1.0e-08	0.63	0.02	0.76	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TNFRSF6B	0.03	0.01	blup	44	0.02	7.1e-04	-6.1	-5.7	1.4e-08	0.75	0.05	0.82	FALSE
11	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	-6.1	5.6	1.8e-08	-0.74	0.19	0.75	FALSE
13	METSIM	Adipose	DNAJC5	0.03	0.00	blup	201	0.01	2.0e-02	-4.1	-5.4	5.9e-08	0.60	0.08	0.42	FALSE
8	GTEx	Esophagus Muscularis	GMEB2	0.11	0.02	enet	30	0.00	4.5e-01	-6.3	-5.3	1.5e-07	0.36	0.08	0.39	FALSE