TWAS
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Usage
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Genes
Traits
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Traits
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Crohns Disease (2017)
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chr21:15,634,304-17,135,372
Best TWAS P=1.28e-08 · Best GWAS P=2.68e-27 conditioned to 2.23e-20
15.6M
15.8M
16M
16.2M
16.4M
16.6M
16.8M
17M
17.2M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
NRIP1
0.08
0.03
bslmm
583
0.01
0.016
5.8
-5.7
1.3e-08
0.59
0.13
0.69
TRUE