TWAS hub - NRIP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0800	0.0280	1.5e-03	0.030	0.008	-0.001	0.011	0.010	1.4e-04	2.8e-02	4.2e-01	1.6e-02	1.7e-02
2	YFS	Blood	0.0363	0.0102	8.8e-06	0.017	0.015	0.019	0.015	0.020	1.9e-06	5.6e-06	5.0e-07	7.7e-06	2.8e-07
3	TCGA	Prostate Adenocarcinoma	0.0919	0.0335	3.2e-05	0.090	0.061	0.076	NA	0.082	1.3e-09	5.3e-07	2.4e-08	NA	6.0e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Wears glasses or contact lenses	6.6	7.6	14.1	-2.1	-2.1	-3.7
Irritable Bowel Disease (IBD)	5.2	12.5	36.6	-6.0	-0.8	-0.3
Crohns Disease (2017)	5.1	11.1	32.4	-5.7	-1.0	-0.1
Mouth/teeth dental problems: Loose teeth	3.9	4.7	13.2	-0.8	0.3	-3.6
Hypothyroidism/myxoedema (self-reported)	3.8	7.4	17.0	-4.1	0.7	-2.2
Medication: Atenolol	3.6	4.5	7.4	-2.7	-0.5	-2.4
Crohns Disease (2012)	3.3	5.3	15.4	-3.9	-0.4	-0.6
Hayfever/allergic rhinitis (self-reported)	3.3	4.3	7.7	-2.8	-1.4	-1.8
Average weekly spirits intake	3.2	3.9	6.4	-0.7	-2.5	-2.2
Ulcerative Colitis (UC)	3.1	5.9	17.3	-4.2	-0.5	-0.4
Hypothyroidism (self reported)	3.0	6.9	18.0	-4.2	0.7	-1.5
Taking other prescription medications	2.9	4.5	12.1	-3.5	-1.1	-0.5
Medication: Levothyroxine sodium	2.9	4.8	12.7	-3.6	-0.2	-1.3
Back pain experienced in last month	2.8	4.1	6.9	-2.1	-0.9	-2.6
Illnesses of siblings: Diabetes	2.7	3.3	7.2	-1.6	-0.5	-2.7
Migraine (self-reported)	2.6	3.2	4.6	2.0	2.1	1.1
Guilty feelings	2.6	3.9	10.8	-3.3	-0.4	-0.9
Qualifications: O levels/GCSEs or equivalent	2.5	3.9	4.4	2.1	2.1	1.7
Major Depression (MDD)	2.4	2.9	3.6	-1.4	-1.8	-1.9
Allergy	2.4	5.4	10.5	3.2	2.1	1.2
Emphysema/chronic bronchitis	2.4	2.7	6.1	0.4	-2.5	-1.4
Suffer from ‘nerves’	2.4	3.8	11.0	-0.2	-3.3	0.6
Worry (Nagel 2018)	2.3	4.9	11.9	-1.6	-3.5	-0.5
Coronary Artery Disease (CAD)	2.2	2.7	7.1	-0.6	-2.7	0.7
Ulcerative Colitis	2.2	3.2	6.0	-2.5	-1.5	-1.1
Financial situation satisfaction	2.2	2.7	3.4	1.3	1.7	1.8
Medication for hormone replacement therapy	2.1	2.3	2.8	1.5	1.7	1.4
Had other major operations	2.1	2.5	5.2	-0.8	-2.3	1.3
Noisy workplace	2.1	2.6	4.1	-0.4	-1.9	-2.0
Birth weight of first child	2.1	3.8	7.5	-2.0	-0.2	-2.7
Medication: Ventolin 100micrograms inhaler	2.1	2.7	5.8	-1.5	-2.4	0.0
Schizophrenia vs Biploar Disorder	2.0	2.6	4.8	0.3	-1.7	2.2
HDL Cholesterol	1.9	3.2	8.4	1.0	0.4	2.9
Medication: Cholesterol lowering	1.9	3.0	5.9	-1.7	-2.4	0.3
High cholesterol (Self-reported)	1.9	3.4	9.5	-0.7	-3.1	-0.3
Schizophrenia (2018)	1.8	3.6	10.8	0.1	0.4	3.3
Fasting Glucose	1.8	2.1	6.1	0.3	-2.5	-0.4
Qualifications: A levels/AS levels or equivalent	1.8	4.0	8.0	2.8	0.2	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	3.8	-1.2	-1.8	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	3.6	-0.9	-1.4	-1.9
Illnesses of father: Heart disease	1.8	2.5	3.1	-1.6	-1.8	1.3
Medication for cholesterol	1.8	2.8	4.5	-2.1	0.4	-1.9
Rheumatoid Arthritis	1.7	2.3	5.0	-1.1	0.8	2.2
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	3.5	-1.9	-0.6	-1.4
Eye problems/disorders: None of the above	1.7	2.0	4.4	2.1	0.1	1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	4.6	0.4	-0.8	2.1
Neuroticism (Nagel 2018)	1.6	3.8	6.2	-2.5	-2.2	-0.5
Nervous feelings	1.6	3.0	6.3	-1.3	-2.5	-1.0
Peak expiratory flow (PEF)	1.6	3.7	10.4	0.8	-3.2	-0.0
Worry too long after embarrassment	1.6	2.7	6.6	-2.6	-1.0	0.6
Heart attack	1.5	1.9	4.5	-2.1	-0.7	-0.7
Pulse wave peak to peak time	1.5	1.8	3.3	1.8	-0.9	1.1
Tinnitus: Yes, now most or all of the time	1.5	1.8	4.3	1.0	0.0	-2.1
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.9	-0.6	-2.0	-0.7
Blood White Count	1.4	10.6	26.9	1.5	1.6	5.2
Ever used hormone-replacement therapy (HRT)	1.4	1.8	2.5	1.6	-0.6	1.6
Forced vital capacity (FVC)	1.4	5.5	15.6	0.9	-3.9	-0.4
Asthma	1.4	2.7	5.7	-1.4	-2.4	-0.8
Pulse wave Arterial Stiffness index	1.4	1.6	3.1	-1.8	0.7	-1.1
Medication: Paracetamol	1.4	2.3	3.9	1.7	2.0	0.3
Wheeze or whistling in the chest in last year	1.4	2.4	4.6	-2.2	-0.9	-1.3
Medication: Seretide 50 evohaler	1.4	1.6	3.6	0.6	-1.9	-0.9
Friendships satisfaction	1.4	1.8	3.7	1.1	1.9	0.7
Age at First Birth	1.3	1.9	3.6	1.9	0.7	1.3
LDL Cholesterol	1.3	2.0	4.8	-1.0	-0.5	-2.2
High blood pressure (mother)	1.3	1.8	2.6	1.4	1.6	1.0
Pulse rate	1.3	2.3	6.4	-2.5	0.2	0.6
Forced vital capacity (FVC), Best measure	1.3	4.7	13.3	0.7	-3.6	0.7
Medication: Atorvastatin	1.3	1.6	3.5	0.2	-1.9	1.1
Unable to work because of sickness or disability	1.3	1.7	2.5	1.2	1.6	1.1
Lupus	1.2	1.8	3.5	-0.1	-1.9	1.4
Triglycerides	1.2	2.0	2.8	-1.7	-1.1	-1.3
Blood Platelet Count	1.2	14.3	33.5	1.4	2.7	5.8
Neuroticism	1.2	2.9	5.4	-1.6	-2.3	-0.8
Number of treatments/medications taken	1.2	2.2	4.5	-2.1	-1.1	-1.0
Sensitivity / hurt feelings	1.2	2.0	4.8	-2.2	-0.7	-0.7
Relative age of first facial hair	1.2	2.4	4.0	0.2	1.8	-2.0
Length of working week for main job	1.2	1.3	3.8	1.9	0.2	-0.1
Chronic bronchitis/emphysema (mother)	1.2	1.3	4.0	-0.2	0.1	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.6	-1.6	1.2	-0.5
Medication: Gliclazide	1.2	1.4	3.0	-0.8	0.8	-1.7
Ever smoked	1.2	2.1	6.4	0.0	0.2	-2.5
Heart attack/myocardial infarction (self-reported)	1.2	1.5	3.8	-1.9	-0.6	-0.7
Serious illness, injury or assault to yourself	1.1	1.3	2.4	1.5	-1.1	0.5
Hayfever, allergic rhinitis or eczema	1.1	2.4	6.3	-2.5	-0.9	-0.5
Exposure to tobacco smoke at home	1.1	1.2	2.5	1.0	-0.1	1.6
Family relationship satisfaction	1.1	1.3	1.8	1.4	-1.2	0.8
Eye problems/disorders: Cataract	1.1	1.2	2.3	-1.5	0.7	-0.9
Asthma (self-reported)	1.1	2.3	4.5	-1.3	-2.1	-0.8
Number of self-reported non-cancer illnesses	1.1	1.9	3.6	-1.1	-1.9	-0.9
Myopia	1.1	1.6	3.6	-0.6	-0.8	-1.9
Alzheimer’s Disease (in mother)	1.0	1.2	2.5	1.0	0.1	1.6
Ovarian Cancer	1.0	1.3	3.1	0.2	1.8	-0.9
Allergy or Eczema	1.0	2.5	6.4	-2.5	-1.1	0.0
Hearing difficulty/problems: Yes	1.0	1.5	2.5	0.4	-1.4	1.6
Supplements: Glucosamine	1.0	1.3	3.6	1.9	0.5	-0.3
Mouth/teeth dental problems	1.0	1.5	4.4	0.1	2.1	-0.4
Medication: Simvastatin	1.0	1.5	2.1	-1.1	-1.0	-1.5
Neuroticism score	1.0	2.2	4.3	-1.3	-2.1	-0.7
Worrier / anxious feelings	1.0	1.9	3.5	-1.4	-1.9	0.2
Hair/balding pattern: Pattern 3	1.0	1.4	3.2	0.9	1.8	-0.5
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	8.9	1.0	-3.0	-0.7
Illnesses of mother	1.0	1.2	2.5	-1.1	0.1	-1.6
Body fat percentage	1.0	3.9	11.5	0.4	3.4	-0.2
Arm fat percentage (left)	1.0	3.9	11.5	0.2	3.4	-0.5
Mood swings	1.0	1.7	2.6	-1.6	-1.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.4	0.6	1.6	0.8
Breast cancer (self-reported)	1.0	1.2	1.7	1.1	0.9	1.3
Illnesses of father: None of the above (group 1)	1.0	1.3	2.2	1.1	1.5	0.6
Bipolar Disorder or Schizophrenia	0.9	2.2	6.4	-0.0	0.3	2.5
Neuroticism (2016)	0.9	1.3	3.4	-0.7	-1.9	0.1
Time employed in main current job	0.9	1.0	2.8	-0.2	0.3	1.7
Falls in the last year	0.9	1.2	1.8	1.2	1.4	-0.4
Medication: Lansoprazole	0.9	1.1	1.4	-1.2	-1.1	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	7.8	0.8	-2.8	0.0
Birth weight	0.9	1.9	3.2	-1.4	-0.7	-1.8
Comparative body size at age 10	0.9	2.5	4.7	0.4	2.2	-1.6
Medication for pain relief, constipation, heartburn	0.9	1.5	2.5	-1.1	-1.6	-0.9
Ever had bowel cancer screening	0.9	1.1	1.7	-1.1	1.3	0.7
Hearing aid user	0.9	1.0	2.6	1.6	0.4	0.4
Supplements: Fish oil (including cod liver oil)	0.9	1.1	1.9	1.1	-1.4	-0.6
Leg fat percentage (left)	0.9	3.4	9.8	-0.0	3.1	-0.7
Commuting to job workplace: Cycle	0.9	1.1	3.1	1.7	-0.1	0.4
Schizophrenia (2014)	0.8	1.7	4.8	-0.3	-0.5	2.2
Pack years adult smoking proportion	0.8	1.2	2.8	-1.7	-0.8	0.3
Trunk fat percentage	0.8	3.3	9.6	0.3	3.1	-0.3
Arm fat percentage (right)	0.8	3.1	9.2	0.1	3.0	-0.2
Hip circumference	0.8	3.2	9.2	0.6	3.0	-0.3
Number of live births	0.8	1.1	1.9	1.0	0.7	1.4
Mouth/teeth dental problems: Dentures	0.8	1.3	2.3	-1.2	-1.5	-0.4
Tense / ‘highly strung’	0.8	1.4	2.8	1.1	-1.7	0.0
Blood clot in the leg (DVT)	0.8	1.0	1.8	1.4	0.4	1.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.7	1.6	1.2	0.1
Leg fat percentage (right)	0.8	3.0	8.9	-0.1	3.0	-0.5
Exposure to tobacco smoke outside home	0.8	1.0	1.3	1.1	1.1	0.8
Number of children fathered	0.8	1.0	2.5	0.5	1.6	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.1	0.3	1.5	-0.7
Age at first live birth	0.8	1.5	4.1	-0.4	-2.0	-0.4
Number of full sisters	0.8	1.0	2.7	1.6	0.6	-0.0
Qualifications: nursing, teaching	0.8	1.3	3.6	1.9	0.3	0.3
Medication: Aspirin	0.8	1.1	1.3	-0.9	-1.1	-1.0
Ever taken oral contraceptive pill	0.8	0.9	2.4	0.1	-1.5	0.4
Cholesterol lowering medication	0.8	1.2	1.9	0.8	-1.1	-1.4
Depression (Nagel 2018)	0.7	1.1	1.9	-1.0	-1.4	0.7
Alzheimer’s Disease (in father)	0.7	0.7	2.0	-1.4	-0.2	0.4
Bipolar Disorder (2011)	0.7	0.7	1.9	-1.4	0.3	0.0
Cardiovascular Disease	0.7	2.3	4.5	0.8	-2.1	1.3
Hand grip strength (left)	0.7	1.9	2.4	-1.4	-1.5	-1.1
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.5	-0.6	-1.6	0.4
Diabetes (father)	0.7	0.9	2.5	-1.6	0.1	-0.3
Hand grip strength (right)	0.7	1.8	3.5	-1.4	-1.9	0.2
Townsend deprivation index at recruitment	0.7	1.0	1.3	0.8	1.1	1.2
Chronic bronchitis/emphysema (father)	0.7	0.9	1.8	0.3	0.8	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.8	1.3	0.8	0.2
Arm fat mass (right)	0.7	2.9	8.5	0.3	2.9	-0.4
Loud music exposure frequency	0.7	0.7	2.1	0.0	-1.5	0.1
High blood pressure (siblings)	0.7	1.0	2.9	-0.2	-0.0	1.7
Angina (self-reported)	0.7	1.0	2.1	-1.4	-0.9	-0.3
Whole body fat mass	0.7	2.8	8.0	0.2	2.8	-0.7
Leg fat mass (right)	0.7	2.7	7.3	0.2	2.7	-0.9
Chest pain or discomfort	0.7	0.9	1.9	-1.4	-0.3	-0.9
Had major operations	0.7	0.9	1.5	-1.2	0.8	-0.7
Leg pain on walking	0.7	0.9	2.5	-0.3	-0.4	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.1	0.7	-0.8	1.4
Arm fat mass (left)	0.7	2.8	8.0	0.4	2.8	-0.6
Alcohol drinker status: Never	0.7	0.8	2.3	0.1	0.3	1.5
Pack years of smoking	0.7	1.0	2.3	-1.5	-0.5	0.7
Leg fat mass (left)	0.7	2.9	7.7	0.2	2.8	-0.9
Reaction Time	0.6	1.1	2.7	1.6	-0.0	0.9
Blood Eosinophil Count	0.6	4.7	12.5	-3.5	-1.2	0.6
Blood Red Count	0.6	6.0	14.1	-3.8	1.5	-1.3
Lung FVC	0.6	2.9	8.4	0.6	-2.9	-0.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.1	-1.0	0.6	-1.0
Medication: Metformin	0.6	0.9	2.7	-0.1	-0.1	-1.6
Current tobacco smoking	0.6	0.9	2.3	-0.6	0.2	-1.5
Body mass index (BMI)	0.6	2.6	6.9	-0.0	2.6	-0.9
Trunk fat mass	0.6	2.4	6.8	0.4	2.6	-0.3
Waist circumference	0.6	2.2	6.2	0.0	2.5	-0.6
Past tobacco smoking	0.6	1.1	2.4	-0.8	-0.4	1.6
Alcohol usually taken with meals	0.6	1.0	1.3	-0.9	0.9	1.1
Qualifications: None of the above	0.6	1.3	2.3	-1.2	1.5	0.4
Pain all over the body in last month	0.6	0.6	1.7	0.1	1.3	-0.2
Prospective memory result	0.6	0.7	1.1	-1.0	0.4	-1.0
Hair/balding pattern: Pattern 4	0.6	1.4	4.0	-2.0	-0.3	-0.2
Medication: Aspirin	0.6	0.8	1.2	-0.5	-1.1	-1.0
Mineral and other dietary supplements	0.6	0.8	1.3	-1.1	0.3	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.1	0.5	-1.8	-0.5
Risk taking	0.6	0.9	1.9	-0.3	-0.9	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	1.4	1.2	0.0	0.9
HbA1C	0.5	0.6	1.1	-0.7	-1.0	0.3
Respiratory disease	0.5	1.1	2.3	-1.0	-1.5	-0.4
Ever had hysterectomy (womb removed)	0.5	0.6	1.2	0.7	0.4	1.1
Angina	0.5	0.7	1.3	-1.1	-0.8	-0.2
Supplements: Zinc	0.5	0.5	1.4	-0.4	0.2	1.2
Medication: Co-codamol	0.5	0.6	0.9	-0.4	-1.0	-0.8
Diabetes (mother)	0.5	0.7	1.0	0.5	-1.0	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.6	0.3	0.4	1.3
Relative age voice broke	0.5	0.8	1.8	0.4	0.7	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.9	-1.4	-1.0	-0.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	0.8	-0.2	1.1
Medication: Ramipril	0.5	0.6	1.3	0.7	0.3	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.2	0.5	1.1	0.6
Number of full brothers	0.5	0.6	0.8	0.8	-0.9	0.5
Neck or shoulder pain in last month	0.5	0.7	1.7	-1.3	-0.6	-0.1
Mean time to correctly identify matches	0.5	0.9	1.6	1.3	0.2	1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.9	-1.4	-0.1	0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.5	0.0	-1.2	-0.6
Diabetes diagnosed by doctor	0.5	0.9	2.2	-0.4	0.5	-1.5
Osteoporosis (self-reported)	0.5	0.6	1.6	-0.4	0.2	-1.2
Smoking status: Current	0.5	0.8	1.8	-0.5	0.5	-1.3
Medication: Paracetamol	0.5	0.8	1.4	1.0	1.2	0.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.4	-0.5	-0.2	1.2
Basal cell carcinoma (self-reported)	0.5	0.6	1.2	-1.1	-0.4	0.6
Alzheimer’s Disease (including proxy)	0.4	0.6	1.6	-0.0	-0.5	1.3
Primary Biliary Cirrhosis	0.4	0.5	0.9	1.0	0.5	0.6
BMI	0.4	2.0	3.9	0.7	2.0	-1.3
Chronotype (morning person)	0.4	0.9	1.8	-1.4	0.2	-0.8
Vitamin and mineral supplements	0.4	0.5	1.3	0.5	-0.2	1.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.1	-0.7	0.1	1.0
Multivitamins +/- minerals	0.4	0.5	0.8	0.9	0.5	0.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.7	0.6	-0.6	-0.8
Diabetes (self-reported)	0.4	0.6	1.4	-0.4	0.5	-1.2
Father’s age at death	0.4	0.5	1.1	0.2	1.1	0.6
Medication: Amlodipine	0.4	0.5	1.2	0.6	-1.1	-0.2
Medication: Blood pressure	0.4	0.8	1.7	-1.3	-0.7	-0.3
Heart disease (mother)	0.4	0.5	0.8	-0.3	-0.9	0.7
Overall health rating	0.4	0.9	1.9	-0.2	0.9	1.4
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.2	-1.1	0.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	1.7	0.1	1.3	-0.7
Long-standing illness, disability or infirmity	0.4	0.6	1.2	-0.0	-0.9	-1.1
Mother’s age at death	0.4	0.5	1.2	1.1	-0.1	0.5
Medication: Bendroflumethiazide	0.4	0.6	0.9	0.6	-0.7	1.0
Fractured/broken bones in last 5 years	0.4	0.5	0.8	0.3	0.9	-0.7
Ever depressed for a whole week	0.4	0.5	1.6	-0.2	-0.2	-1.2
Depressed Affect (Nagel 2018)	0.3	0.6	1.0	-1.0	-0.7	-0.6
Systolic Blood Pressure	0.3	1.3	2.4	1.1	-0.6	1.6
Smoking Status	0.3	0.6	1.6	-0.3	-0.5	-1.2
Qualifications: CSEs or equivalent	0.3	0.5	1.4	-0.0	1.2	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.8	-0.3	-0.9	0.6
Hair/balding pattern: Pattern 2	0.3	0.4	1.0	-0.6	-1.0	0.0
Financial difficulties in last 2 years	0.3	0.3	0.7	0.4	0.4	0.8
Fluid intelligence score	0.3	0.6	1.5	1.2	0.1	0.5
Weight	0.3	1.5	3.9	0.5	2.0	-0.7
Happiness	0.3	0.4	0.7	0.9	0.5	0.4
Breastfed as a baby	0.3	0.4	1.0	0.5	-0.3	1.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	0.7	-0.4	-0.3	0.8
Headache pain in last month	0.3	0.6	1.1	-0.1	-1.1	-0.7
Health satisfaction	0.3	0.4	1.0	0.1	-0.5	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.9	0.9	0.4	-0.3
Smoking status: Previous	0.3	0.5	1.2	0.3	0.4	-1.1
Miserableness	0.3	0.6	0.8	-0.9	0.4	-0.9
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.5	-0.3	0.6	-0.7
Illnesses of father: High blood pressure	0.3	0.4	0.6	0.4	-0.8	0.7
Number of operations (self-reported)	0.3	0.4	0.8	0.9	-0.2	0.7
Irritability	0.3	0.5	0.9	0.2	-0.9	-0.8
Age started oral contraceptive pill	0.3	0.3	0.5	0.4	0.7	0.6
Diastolic blood pressure, automated reading	0.3	0.9	2.0	0.8	1.4	-0.4
Heart disease (siblings)	0.3	0.4	0.8	0.4	-0.9	-0.5
Body Mass Index (BMI) (2010)	0.2	0.3	0.6	-0.5	0.3	-0.7
Lung FEV1/FVC ratio	0.2	1.2	2.3	1.0	1.5	-0.6
Age when periods started (menarche)	0.2	0.6	1.7	0.1	1.3	0.2
Stomach or abdominal pain in last month	0.2	0.2	0.6	-0.3	-0.8	-0.0
Number of incorrect matches in round	0.2	0.3	0.7	0.8	-0.4	-0.2
Hearing difficulty/problems with background noise	0.2	0.3	0.4	0.1	-0.6	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.9	-0.6	-0.2	0.9
Illnesses of siblings	0.2	0.2	0.5	0.7	0.4	-0.2
Pulse wave reflection index	0.2	0.2	0.7	0.0	-0.0	-0.9
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	0.3	-0.1	-0.7
Medication: Ibuprofen	0.2	0.3	0.5	0.7	0.4	0.3
Medication: Omeprazole	0.2	0.2	0.5	0.0	0.3	0.7
Alcohol intake frequency.	0.2	0.5	1.1	-0.3	0.6	-1.0
Comparative height size at age 10	0.2	1.2	3.0	0.8	-1.7	0.4
Age at last live birth	0.2	0.2	0.4	-0.2	-0.6	-0.6
Knee pain experienced in last month	0.2	0.3	0.9	-0.0	0.2	0.9
Average weekly red wine intake	0.2	0.4	1.1	-0.1	0.1	1.0
Loneliness, isolation	0.2	0.2	0.6	-0.2	0.8	-0.3
Osteoarthritis (self-reported)	0.2	0.3	0.5	0.5	-0.2	-0.7
Average weekly champagne plus white wine intake	0.2	0.2	0.5	0.4	0.3	-0.7
Eye problems/disorders: Glaucoma	0.2	0.3	0.4	0.5	0.6	-0.3
Medication: Blood pressure	0.2	0.4	0.8	0.9	-0.5	0.5
Medication: Lisinopril	0.2	0.3	0.6	-0.7	-0.3	-0.5
Average weekly beer plus cider intake	0.2	0.3	0.7	0.4	-0.1	0.8
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.4	-0.7	-0.6	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.4	0.1	-0.1	0.7
Breast Cancer	0.1	0.2	0.3	-0.4	-0.3	-0.6
Prostate Cancer	0.1	0.1	0.1	0.4	0.1	-0.2
Mean Putamen Volume	0.1	0.1	0.3	-0.2	0.6	0.1
Heel T-Score	0.1	0.9	1.3	0.5	1.1	1.1
Height	0.1	1.8	2.6	1.6	-1.5	-0.7
Waist Hip Ratio (WHR)	0.1	0.2	0.7	-0.2	-0.1	-0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.4	-0.6	0.4	-0.4
Hair Pigment	0.1	2.3	4.3	-2.1	-1.1	1.1
Systolic blood pressure, automated reading	0.1	0.3	0.8	0.9	-0.1	-0.1
Severe depression (siblings)	0.1	0.1	0.3	0.1	0.5	0.1
Impedance of leg (right)	0.1	0.3	0.6	0.3	0.8	0.5
Average weekly fortified wine intake	0.1	0.2	0.2	0.5	-0.4	-0.2
Fed-up feelings	0.1	0.1	0.2	-0.4	0.5	-0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	0.1	-0.1	-0.5
High blood pressure	0.1	0.2	0.4	0.5	-0.2	0.6
Sitting height	0.1	0.8	1.7	1.3	-0.7	0.3
Impedance of leg (left)	0.1	0.4	0.9	0.1	0.9	0.4
Had menopause	0.1	0.2	0.5	0.7	-0.1	-0.1
Impedance of arm (right)	0.1	0.5	1.1	0.4	0.4	1.0
Trunk fat-free mass	0.1	0.5	1.3	0.2	-1.2	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.2	-0.2	0.5	-0.3
Depression (self-reported)	0.1	0.1	0.2	-0.3	-0.4	-0.2
Impedance of arm (left)	0.1	0.7	1.4	0.6	1.2	0.6
Trunk predicted mass	0.1	0.6	1.5	0.3	-1.2	-0.4
Standing height	0.1	0.9	1.6	1.0	-1.3	-0.1
Glaucoma (self-reported)	0.1	0.1	0.2	0.2	0.2	-0.4
Arm fat-free mass (right)	0.1	0.4	0.5	0.6	-0.6	-0.7
Shortness of breath walking on level ground	0.1	0.1	0.4	0.2	-0.6	-0.0
Qualifications: College or University degree	0.1	0.3	0.6	-0.7	0.1	0.8
Medication: Allopurinol	0.1	0.2	0.3	-0.1	0.5	0.6
Arm predicted mass (right)	0.1	0.4	0.7	0.7	-0.3	-0.8
Pulse rate, automated reading	0.1	0.3	0.6	0.4	0.8	0.4
Hypertension (Self-reported)	0.1	0.4	0.7	0.6	0.3	0.8
Commuting to job workplace: Walk	0.1	0.1	0.2	0.5	0.1	0.1
Commuting to job workplace: Public transport	0.1	0.1	0.2	-0.4	0.4	-0.1
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.4	-0.3	0.6	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	0.4	0.3	0.6
Pain experienced in last month	0.1	0.2	0.6	0.8	-0.2	-0.1
Impedance of whole body	0.1	0.7	0.9	0.7	1.0	0.8
Bipolar Disorder (2018)	0.0	0.0	0.0	-0.1	-0.0	-0.0
Tanning	0.0	0.1	0.3	-0.1	-0.4	0.5
Leg fat-free mass (left)	0.0	0.2	0.3	0.6	0.3	-0.4
Maternal smoking around birth	0.0	0.1	0.1	0.4	0.1	-0.1
Leg predicted mass (left)	0.0	0.2	0.3	0.6	0.2	-0.4
Alcohol intake versus 10 years previously	0.0	0.0	0.0	0.1	-0.1	-0.1
Lung cancer (father)	0.0	0.0	0.1	0.3	0.1	0.3
Gout (self-reported)	0.0	0.0	0.1	-0.3	-0.2	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.3	0.2	-0.1
Supplements: Vitamin C	0.0	0.0	0.1	-0.1	0.3	0.0
Whole body fat-free mass	0.0	0.2	0.4	0.4	-0.6	-0.3
Leg fat-free mass (right)	0.0	0.1	0.3	0.5	-0.0	-0.4
Whole body water mass	0.0	0.2	0.3	0.5	-0.5	-0.3
Leg predicted mass (right)	0.0	0.1	0.2	0.5	-0.1	-0.5
Basal metabolic rate	0.0	0.1	0.3	0.5	0.1	-0.3
Arm fat-free mass (left)	0.0	0.2	0.2	0.4	-0.4	-0.4
Supplements: Calcium	0.0	0.0	0.0	-0.1	-0.0	-0.0
Alcohol drinker status: Previous	0.0	0.0	0.1	0.3	-0.1	-0.2
Arm predicted mass (left)	0.0	0.2	0.4	0.7	-0.3	-0.4

Hub : Genes

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Trait associations