[Hub]/) : Traits : Crohns Disease (2017) : ← →

chr21:44,948,764-46,443,886

Best TWAS P=3.17e-14 · Best GWAS P=2.02e-19 conditioned to 2.24e-07

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	The Cancer Genome Atlas	Thyroid Carcinoma	ICOSLG	0.11	0.03	blup	68	0.08	5.6e-08	-6.6	-7.6	3.2e-14	-0.70	0.01	0.98	TRUE
1	GTEx	Breast Mammary Tissue (Male)	PFKL	0.27	0.09	lasso	2	0.09	3.5e-03	-5.8	5.7	1.1e-08	0.43	0.06	0.14	FALSE
3	NTR	Blood	ICOSLG	0.05	0.01	enet	17	0.03	2.9e-10	-2.0	-5.7	1.5e-08	-0.57	0.08	0.92	FALSE
4	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ICOSLG	0.14	0.07	blup	68	0.10	8.2e-05	-3.9	-5.7	1.5e-08	-0.47	0.14	0.21	FALSE
2	GTEx	Skin Sun Exposed Lower leg	ICOSLG	0.21	0.08	enet	27	0.10	1.8e-08	-3.8	-5.4	5.4e-08	-0.42	0.88	0.12	FALSE