Best TWAS P=3.17e-14 · Best GWAS P=2.02e-19 conditioned to 2.24e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | PFKL | 0.27 | 0.09 | lasso | 2 | 0.09 | 3.5e-03 | -5.8 | 5.7 | 1.1e-08 | 0.43 | 0.06 | 0.14 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ICOSLG | 0.21 | 0.08 | enet | 27 | 0.10 | 1.8e-08 | -3.8 | -5.4 | 5.4e-08 | -0.42 | 0.88 | 0.12 | FALSE |
| 3 | NTR | Blood | ICOSLG | 0.05 | 0.01 | enet | 17 | 0.03 | 2.9e-10 | -2.0 | -5.7 | 1.5e-08 | -0.57 | 0.08 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ICOSLG | 0.14 | 0.07 | blup | 68 | 0.10 | 8.2e-05 | -3.9 | -5.7 | 1.5e-08 | -0.47 | 0.14 | 0.21 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | ICOSLG | 0.11 | 0.03 | blup | 68 | 0.08 | 5.6e-08 | -6.6 | -7.6 | 3.2e-14 | -0.70 | 0.01 | 0.98 | TRUE |