TWAS hub - ICOSLG

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.1270	0.0500	5.5e-03	0.081	NA	0.028	NA	0.063	1.2e-06	NA	3.4e-03	NA	1.8e-05
2	GTEx	Esophagus Muscularis	0.1600	0.0570	4.4e-03	0.067	NA	0.077	NA	0.086	6.5e-05	NA	2.0e-05	NA	7.0e-06
3	GTEx	Skin Not Sun Exposed Suprapubic	0.2290	0.0820	3.8e-03	0.023	NA	0.048	NA	0.042	1.9e-02	NA	1.2e-03	NA	2.3e-03
4	GTEx	Skin Sun Exposed Lower leg	0.2060	0.0580	6.3e-05	0.084	NA	0.098	NA	0.092	1.8e-07	NA	1.7e-08	NA	4.8e-08
5	METSIM	Adipose	0.0840	0.0341	2.5e-03	0.023	0.028	0.030	0.036	0.034	1.9e-04	3.6e-05	2.3e-05	3.8e-06	5.9e-06
6	NTR	Blood	0.0518	0.0155	3.2e-06	0.012	0.028	0.031	0.027	0.025	6.9e-05	1.7e-09	2.9e-10	3.3e-09	1.4e-08
7	TCGA	Bladder Urothelial Carcinoma	0.0680	0.0270	1.6e-04	0.025	0.033	0.036	NA	0.035	3.2e-03	8.0e-04	4.5e-04	NA	6.1e-04
8	TCGA	Breast Invasive Carcinoma	0.0734	0.0217	1.5e-10	0.045	0.053	0.050	NA	0.051	1.2e-09	4.1e-11	1.5e-10	NA	1.1e-10
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0956	0.0288	9.6e-09	0.080	0.097	0.084	NA	0.095	2.8e-09	5.9e-11	1.0e-09	NA	7.9e-11
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0886	0.0324	4.5e-06	0.059	0.054	0.043	NA	0.043	3.4e-07	1.1e-06	1.1e-05	NA	1.2e-05
11	TCGA	Liver Hepatocellular Carcinoma	0.1520	0.0710	2.1e-03	0.020	0.035	0.030	NA	0.023	4.0e-02	8.9e-03	1.4e-02	NA	2.9e-02
12	TCGA	Lung Adenocarcinoma	0.0503	0.0232	1.3e-03	0.005	0.019	0.015	NA	0.010	7.8e-02	2.4e-03	6.9e-03	NA	2.2e-02
13	TCGA	Lung Squamous Cell Carcinoma	0.0491	0.0219	1.6e-03	0.011	0.022	0.023	NA	0.021	1.7e-02	1.4e-03	9.7e-04	NA	1.7e-03
14	TCGA	Pheochromocytoma and Paraganglioma	0.1380	0.0590	1.2e-03	0.073	0.101	0.068	NA	0.062	7.5e-04	8.2e-05	1.1e-03	NA	1.9e-03
15	TCGA	Prostate Adenocarcinoma	0.1402	0.0416	6.0e-10	0.057	0.108	0.113	NA	0.122	1.2e-06	2.5e-11	7.5e-12	NA	9.9e-13
16	TCGA	Thyroid Carcinoma	0.1150	0.0430	1.4e-06	0.029	0.077	0.068	NA	0.055	6.7e-04	5.6e-08	3.5e-07	NA	4.9e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Irritable Bowel Disease (IBD)	12.4	29.5	83.4	5.7	1.5	-4.2	-5.9	-2.1	-6.1	-4.1	-5.0	-4.6	-4.3	-6.7	-5.4	-5.3	-7.0	-5.3	-9.1
Crohns Disease (2017)	9.3	20.4	57.6	4.4	1.2	-3.7	-5.4	-1.6	-5.7	-3.5	-4.1	-3.4	-3.4	-4.9	-4.6	-4.7	-5.7	-4.2	-7.6
Ulcerative Colitis (UC)	9.3	17.5	48.4	4.2	0.8	-3.3	-4.1	-2.6	-4.5	-3.1	-3.7	-4.1	-3.5	-5.5	-4.1	-4.1	-5.2	-3.8	-7.0
Primary Biliary Cirrhosis	7.1	10.1	18.6	1.3	-2.1	-4.3	-3.3	-3.1	-3.9	-4.3	-2.6	-3.7	-2.5	-3.0	-3.6	-2.2	-4.0	-2.0	-3.2
Ulcerative Colitis	6.9	10.0	31.4	3.5	0.9	-2.6	-3.3	-2.5	-3.5	-1.8	-2.4	-3.2	-2.6	-3.8	-3.1	-3.1	-3.8	-2.0	-5.6
Crohns Disease (2012)	6.7	10.8	35.9	3.6	1.3	-2.4	-3.9	-1.3	-4.7	-2.1	-2.8	-2.2	-2.8	-2.5	-3.3	-3.9	-3.6	-2.5	-6.0
Rheumatoid Arthritis	5.1	7.0	13.8	2.6	0.1	-2.6	-2.7	-0.8	-1.9	-3.2	-1.9	-2.9	-3.1	-3.7	-2.5	-2.4	-3.5	-3.4	-2.0
Blood Eosinophil Count	4.9	37.6	86.8	-2.3	-7.9	-9.3	-6.7	-8.5	-6.7	-7.9	-3.3	-7.8	-5.5	-4.1	-6.1	-6.2	-4.7	-1.3	-2.0
Average weekly fortified wine intake	4.8	5.7	12.3	-0.9	-0.1	2.3	2.5	1.1	2.2	2.4	1.9	2.8	3.2	2.6	2.9	2.9	3.5	2.2	2.0
Bilateral oophorectomy (both ovaries removed)	4.1	4.7	10.7	-0.7	0.7	2.1	3.3	0.9	2.7	2.7	2.3	2.9	2.4	2.7	1.3	1.8	1.9	1.9	2.4
Heart disease (mother)	2.8	3.4	7.2	-1.3	1.2	1.8	2.2	0.8	1.7	2.0	2.0	2.0	0.4	2.6	2.0	1.2	2.4	1.5	2.7
Pain all over the body in last month	2.6	2.8	7.9	-0.9	-0.5	1.7	2.2	2.3	1.8	1.3	0.8	2.8	2.5	1.7	0.9	1.5	1.9	0.8	1.0
Alcohol intake versus 10 years previously	2.6	3.8	8.6	0.4	-1.1	-1.3	-2.3	-0.5	-1.7	-2.2	-2.7	-1.6	-1.7	-1.8	-2.1	-2.7	-2.0	-2.3	-2.9
Coronary Artery Disease (CAD)	2.5	2.9	7.8	0.7	-0.5	-1.2	-1.2	-0.8	-2.1	-2.1	-1.8	-0.8	-2.1	-0.8	-2.2	-2.5	-1.6	-1.8	-2.8
Commuting to job workplace: Public transport	2.5	3.0	8.7	0.7	-0.2	-2.0	-1.6	-1.4	-1.9	-0.9	-1.3	-2.4	-1.4	-2.0	-2.0	-1.6	-2.4	-0.2	-3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.3	11.1	-1.4	-0.6	0.6	1.9	1.2	2.2	1.0	2.3	1.6	2.2	1.5	1.5	2.3	1.8	1.2	3.3
Gout (self-reported)	2.2	3.0	5.9	0.9	-1.0	-2.2	-1.7	-0.8	-2.4	-2.2	-1.3	-1.9	-1.7	-0.8	-2.4	-2.4	-1.9	-1.2	-1.2
Age at last live birth	2.2	3.2	6.4	-1.4	0.3	1.5	1.1	1.4	1.3	2.3	1.9	2.0	1.3	2.0	2.3	1.9	2.5	2.5	1.3
HbA1C	2.1	2.3	12.0	1.6	3.5	2.2	1.0	2.5	-0.1	1.6	-0.6	1.4	0.0	1.8	0.1	-0.3	0.5	-1.2	0.5
Glaucoma (self-reported)	2.1	2.5	6.3	0.1	-1.9	-2.1	-0.7	-0.5	-0.8	-2.5	-1.5	-2.2	-1.2	-1.7	-1.8	-1.4	-1.9	-1.4	-1.7
Allergy or Eczema	1.9	5.1	13.6	0.4	-1.8	-3.7	-3.0	-2.1	-0.9	-3.0	-1.6	-2.7	-2.0	-2.1	-2.5	-2.1	-2.8	-2.1	-0.1
Ever used hormone-replacement therapy (HRT)	1.9	2.5	8.7	-2.0	-0.7	0.9	2.3	1.0	2.9	1.2	1.1	2.0	1.9	0.9	1.0	1.6	0.9	1.8	0.9
Diabetes (self-reported)	1.9	3.0	5.8	-0.4	-1.3	-2.0	-1.3	-1.0	-1.5	-2.1	-0.9	-2.2	-2.4	-1.1	-2.3	-2.4	-2.3	-1.1	-1.7
Emphysema/chronic bronchitis	1.9	2.1	4.2	-0.3	-1.4	-1.1	-0.7	-1.8	-1.6	-2.0	-2.0	-1.7	-1.3	-0.9	-1.5	-1.8	-1.0	-1.5	-1.5
Medication for hormone replacement therapy	1.8	2.0	6.7	-1.3	-0.5	1.1	2.1	1.1	2.6	0.8	0.5	1.4	1.8	0.9	1.5	1.9	1.0	0.7	1.3
Number of children fathered	1.8	2.1	7.5	-1.9	-0.2	2.2	1.9	1.4	2.7	1.2	-0.4	1.7	0.7	0.9	1.5	0.8	1.6	0.0	-0.1
Average weekly red wine intake	1.8	2.6	5.5	-1.2	0.3	1.7	1.5	1.8	2.3	1.9	1.4	1.9	1.8	1.6	1.2	1.9	1.4	1.2	1.5
Hayfever, allergic rhinitis or eczema	1.7	3.6	12.2	0.6	-1.4	-3.5	-2.8	-2.0	-0.9	-2.3	-1.3	-2.5	-1.4	-2.2	-1.6	-1.0	-2.3	-1.5	-0.1
Neck or shoulder pain in last month	1.7	2.5	6.2	1.5	-0.3	-1.5	-1.5	-0.8	-2.1	-2.4	-2.3	-1.2	0.0	-1.5	-1.5	-0.5	-1.3	-2.5	-1.5
Age started oral contraceptive pill	1.7	2.1	7.2	-0.5	-1.0	1.5	1.9	2.3	2.1	0.8	-0.7	2.7	2.3	0.8	0.6	1.3	0.8	-0.2	-0.7
Heart disease (siblings)	1.7	2.1	5.5	-1.0	0.5	1.3	1.0	1.2	2.3	1.6	2.3	1.5	0.6	1.3	1.3	0.7	1.1	1.9	1.8
Allergy	1.6	3.6	12.8	-0.3	2.0	3.6	2.7	2.2	1.1	2.7	1.2	2.4	1.1	1.9	1.4	1.1	1.8	1.4	-0.1
Medication: Allopurinol	1.6	2.1	4.8	0.7	-0.5	-1.6	-1.7	-0.7	-1.7	-1.8	-1.0	-1.8	-1.9	-1.0	-1.6	-2.2	-1.5	-1.3	-0.7
Commuting to job workplace: Car/motor vehicle	1.6	1.8	5.3	-0.6	0.8	1.6	1.9	2.2	2.3	0.5	0.2	2.1	1.2	0.9	0.6	0.9	1.1	-0.4	1.4
Commuting to job workplace: Cycle	1.6	1.9	6.7	-1.2	-0.8	0.6	1.5	-0.4	1.2	0.7	1.1	1.1	1.3	1.3	1.7	2.3	1.8	0.7	2.6
Noisy workplace	1.5	1.9	3.7	0.8	1.5	1.9	1.0	1.1	0.4	1.2	1.1	1.6	1.4	1.6	1.8	1.3	1.7	0.1	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.9	18.6	0.6	-0.9	-1.6	-1.3	-0.2	-2.1	-1.8	-3.9	-1.9	-1.5	-1.7	-2.6	-2.2	-2.5	-2.3	-4.3
Supplements: Vitamin C	1.5	1.8	7.3	-1.5	-1.3	0.1	1.0	0.2	1.7	1.0	1.1	0.4	1.8	0.1	2.1	2.7	1.0	1.5	0.2
Back pain experienced in last month	1.5	2.1	6.2	1.9	1.1	-1.3	-2.5	-0.5	-1.9	-1.5	0.3	-1.9	-1.9	-1.5	-1.3	-1.2	-1.4	-1.0	-0.5
Number of full sisters	1.4	1.7	4.6	1.3	0.3	-0.9	-1.7	-0.7	-1.7	-1.2	-0.6	-1.8	-1.1	-2.2	-0.4	-0.8	-1.9	-1.0	-1.7
Unable to work because of sickness or disability	1.4	1.9	6.2	0.7	1.1	2.0	1.8	2.5	1.5	1.4	0.6	1.4	1.2	0.6	1.6	1.3	1.5	0.0	0.6
Alzheimer’s Disease (in mother)	1.3	1.5	3.7	-1.2	-1.0	-0.8	-0.1	-0.4	0.6	-1.5	-1.7	-1.2	-1.9	-0.7	-1.1	-1.3	-1.5	-0.9	-1.7
Prostate Cancer	1.3	1.9	4.8	-1.4	-1.0	0.9	1.1	0.6	2.1	1.4	0.4	2.2	1.9	0.9	1.4	1.6	1.5	1.1	0.7
Respiratory disease	1.3	2.9	11.9	-0.9	-3.1	-3.5	-1.9	-2.3	-0.7	-2.6	-0.4	-1.5	-0.6	-1.0	-1.3	-0.9	-1.1	-0.6	0.7
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	9.4	-0.9	-0.6	-2.0	-1.8	-3.1	-1.1	-1.0	0.8	-2.0	-1.6	-0.6	-0.9	-0.9	-1.0	1.1	0.7
Chronic bronchitis/emphysema (mother)	1.3	1.5	7.7	1.8	2.8	0.4	-0.8	-0.5	-1.4	0.2	1.7	-0.1	-1.5	0.9	-0.3	-0.8	0.0	-0.2	1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	3.4	-1.5	-0.3	1.8	1.7	0.9	1.4	1.4	-1.4	1.0	0.8	0.9	1.0	-0.1	1.2	0.8	-1.9
Alcohol intake frequency.	1.3	3.0	6.3	1.2	-0.3	-1.7	-2.5	-0.5	-1.5	-2.3	-1.0	-2.4	-1.7	-2.3	-1.6	-0.9	-2.4	-1.8	-1.3
Alzheimer’s Disease (including proxy)	1.2	1.8	3.9	-1.2	-1.6	-1.5	-0.2	-0.9	0.1	-1.7	-1.5	-1.3	-2.0	-0.4	-1.5	-1.7	-1.4	-0.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	5.5	2.1	2.4	1.4	0.9	1.1	0.1	0.8	-0.5	0.5	1.0	-0.4	1.1	1.5	0.4	-1.5	0.3
Average weekly champagne plus white wine intake	1.2	1.6	3.9	-2.0	0.2	1.6	1.6	0.9	1.4	1.7	0.8	1.3	0.6	0.2	1.4	0.6	1.4	1.9	-0.8
Eye problems/disorders: Glaucoma	1.2	1.5	3.8	0.5	-0.7	-1.1	-0.6	0.0	-1.3	-1.7	-1.6	-1.3	-0.9	-0.8	-1.6	-1.2	-1.2	-1.2	-2.0
Stomach or abdominal pain in last month	1.1	1.4	3.0	1.7	0.9	-0.4	-0.9	0.1	-1.5	-1.1	-1.2	-1.2	-1.3	-0.4	-1.3	-1.7	-1.2	-1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	6.3	-1.5	-1.7	-2.5	-1.1	-1.4	-0.4	-1.1	0.2	-1.5	-0.8	-1.1	-0.5	-0.3	-1.1	0.6	0.8
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	4.7	0.1	0.8	1.2	0.8	1.1	2.2	1.4	1.1	0.9	1.1	-0.0	1.4	1.5	0.9	0.3	1.2
Family relationship satisfaction	1.1	1.4	3.5	-0.9	0.6	1.9	1.6	1.7	1.0	1.1	-0.6	1.7	1.5	0.8	0.9	1.0	1.1	0.2	-0.7
Knee pain experienced in last month	1.1	1.7	6.0	-0.0	-0.6	-1.4	-2.4	-1.0	-0.8	-1.6	0.0	-1.1	-2.0	-1.4	-1.4	-1.3	-1.3	-0.3	-1.5
Medication: Co-codamol	1.0	1.1	3.0	0.3	1.0	0.7	0.1	1.6	1.3	0.9	1.7	1.2	0.7	0.5	1.3	1.1	0.8	0.1	1.7
Current tobacco smoking	1.0	1.7	3.4	-0.9	-0.1	1.6	1.7	0.8	1.9	1.7	-0.3	1.5	1.8	1.2	1.4	1.5	1.6	0.3	0.5
Medication: Atenolol	1.0	1.2	3.2	1.1	0.8	1.3	0.8	1.5	0.3	1.4	1.8	1.3	1.4	0.2	0.9	0.8	1.0	1.0	0.5
Chronic bronchitis/emphysema (father)	1.0	1.2	5.3	1.9	0.7	0.7	-1.0	0.4	-0.8	-0.3	-1.7	0.7	0.7	-0.3	-0.5	0.1	-0.6	-1.5	-2.3
Alcohol usually taken with meals	1.0	1.7	5.2	-1.9	-0.1	1.6	0.8	1.0	2.3	1.8	0.9	1.1	0.4	1.7	0.9	0.4	1.3	1.5	0.8
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	11.0	0.4	-1.0	-1.7	-0.7	0.1	-1.4	-1.8	-3.3	-1.8	-1.2	-1.5	-2.2	-1.8	-2.2	-2.1	-3.1
Pulse rate	1.0	1.7	4.0	1.3	0.1	-1.2	-1.9	-0.7	-1.3	-1.0	-1.5	-1.0	-0.7	-2.0	-1.3	-1.0	-1.5	-1.7	-1.5
Headache pain in last month	1.0	1.7	4.0	1.1	-0.5	-0.7	-1.7	-1.6	-1.9	-1.6	-2.0	-0.6	0.0	0.3	-1.6	-0.8	-0.7	-1.9	-1.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.3	1.0	1.7	0.1	0.4	-0.4	-0.6	-0.4	-1.4	-0.9	-1.8	-1.5	-0.9	-1.8	-1.0	-1.4	-0.6
Qualifications: nursing, teaching	1.0	1.6	5.2	-1.1	-0.9	-1.1	0.4	-2.0	-0.3	0.3	2.1	-1.0	0.5	0.1	0.9	1.5	0.9	2.3	1.7
Mother’s age at death	1.0	1.3	4.6	1.2	1.8	0.5	-0.0	-0.1	0.6	1.7	2.1	0.7	0.7	-0.2	1.3	1.3	0.1	1.3	1.6
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.9	-1.1	-0.5	0.9	1.1	0.6	1.0	1.3	1.2	1.4	0.9	1.7	0.6	0.1	1.3	1.2	1.1
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.3	0.3	0.9	0.0	-0.4	0.3	-0.7	-1.1	-1.8	-0.5	-1.2	-0.4	-0.6	-0.7	-1.2	-2.1	-1.0
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	3.1	-0.5	-0.5	0.6	0.8	0.9	1.5	0.5	-1.2	1.5	1.7	0.1	0.7	1.5	0.7	-0.4	-0.3
Mouth/teeth dental problems	0.9	1.4	5.4	-0.6	-1.0	-1.6	0.0	-1.4	0.2	-0.7	1.9	-1.6	-0.2	-1.2	1.1	1.0	0.0	0.4	2.3
Father’s age at death	0.9	1.2	3.0	0.6	0.9	1.1	1.2	-1.0	-0.5	1.5	0.9	0.3	1.5	1.1	1.0	1.4	1.5	1.7	0.2
Illnesses of mother	0.9	1.1	4.1	-1.3	-2.0	0.3	0.1	1.2	0.2	0.6	-1.1	0.8	1.7	0.2	0.6	1.1	1.0	0.5	-1.4
Blood clot in the leg (DVT)	0.9	1.1	2.5	0.3	1.2	1.1	0.3	0.4	0.5	1.3	1.0	1.0	1.2	1.2	1.1	1.6	1.1	1.1	1.4
Wheeze or whistling in the chest in last year	0.9	1.5	5.4	-0.7	-2.3	-2.0	-0.3	-1.4	-0.1	-2.0	-0.4	-1.8	-0.6	-1.6	-0.6	-0.9	-0.7	-0.7	0.2
Medication: Omeprazole	0.9	1.1	2.9	-1.1	-1.7	-1.1	-0.7	-0.4	0.5	-1.6	-1.3	-1.1	-1.0	-1.1	-0.4	-0.3	-0.9	-1.2	-0.9
Chest pain or discomfort	0.9	1.3	3.7	0.7	-0.3	-1.8	-1.1	-1.1	-1.9	-1.8	1.0	-1.2	-0.8	-0.9	-1.5	-0.3	-0.8	-0.1	0.3
Arm fat percentage (left)	0.9	3.4	7.3	0.4	0.1	-1.4	-2.6	0.2	-1.3	-2.1	-1.9	-1.8	-2.7	-1.0	-2.6	-2.7	-2.1	-1.8	-1.8
Diabetes diagnosed by doctor	0.9	1.4	3.3	-0.2	-0.6	-0.8	-0.5	-0.6	-1.3	-1.3	-1.2	-1.2	-1.7	-0.7	-1.3	-1.8	-1.4	-1.3	-1.8
Smoking status: Current	0.9	1.4	3.1	-0.9	0.1	1.6	1.5	1.1	1.8	1.5	-0.7	1.4	1.5	0.8	1.2	1.1	1.3	-0.0	-0.1
Bipolar Disorder (2018)	0.8	1.3	5.6	1.5	0.8	0.0	-0.5	0.7	-0.9	-0.6	-1.6	-0.0	-0.3	-1.3	-0.7	-0.3	-1.4	-1.7	-2.4
Fasting Glucose	0.8	1.0	3.5	1.6	1.9	0.5	0.2	1.1	0.2	1.3	-0.2	1.5	1.4	0.6	0.2	1.1	0.4	0.2	0.2
Blood Red Count	0.8	8.1	17.0	-0.3	-2.4	-4.0	-3.4	-2.6	-2.4	-3.3	-1.0	-3.3	-3.6	-3.0	-2.9	-4.1	-3.1	-1.1	-1.7
Supplements: Zinc	0.8	0.8	4.4	1.2	0.4	-1.2	-0.1	-0.7	0.5	-0.8	0.7	-0.7	0.2	-2.1	0.1	1.2	-1.2	-0.5	0.5
Diabetes (father)	0.8	1.0	6.3	1.6	2.5	1.1	0.8	0.5	0.2	0.5	-0.4	-0.0	0.6	-0.3	0.8	1.2	0.1	-0.9	0.9
Had menopause	0.8	1.0	3.5	-0.1	-0.7	-1.0	-0.3	0.1	0.3	-0.9	-0.6	-0.1	-1.3	-0.9	-1.8	-1.5	-1.9	-0.4	-1.3
Arm fat percentage (right)	0.8	3.0	7.2	0.3	0.1	-1.2	-2.3	0.2	-1.3	-1.9	-1.7	-1.7	-2.6	-0.8	-2.5	-2.7	-1.9	-1.6	-1.7
Happiness	0.8	1.0	2.3	-0.2	0.5	1.2	1.0	1.1	0.6	1.3	0.8	1.4	1.4	0.4	0.7	1.5	1.0	1.0	0.1
Asthma	0.8	1.5	7.7	-1.2	-2.8	-2.4	-0.7	-1.8	-0.2	-1.6	0.2	-1.2	0.3	-0.6	0.2	0.2	-0.0	0.3	1.0
Arm fat mass (right)	0.8	3.2	7.3	0.4	0.1	-1.0	-2.3	0.6	-1.2	-1.9	-2.2	-1.5	-2.4	-0.8	-2.6	-2.7	-1.9	-1.9	-2.2
Peak expiratory flow (PEF)	0.8	1.9	9.3	0.2	-1.0	-0.7	0.4	0.7	-0.4	-0.9	-2.8	-0.9	0.2	-1.6	-0.9	-0.4	-1.6	-1.7	-3.0
Loud music exposure frequency	0.8	0.8	3.6	-1.9	-1.0	0.7	1.4	-0.3	0.9	0.5	-0.7	1.0	0.6	0.8	1.0	0.3	1.3	0.0	0.2
High blood pressure (siblings)	0.8	1.2	3.7	1.3	1.3	-0.9	-1.9	-0.4	-1.9	-0.3	0.7	-0.5	-1.2	0.6	-1.1	-1.7	-0.7	0.3	0.7
Forced vital capacity (FVC), Best measure	0.8	2.8	13.4	-0.5	-1.3	-1.1	-0.6	0.2	-1.1	-1.1	-3.3	-1.2	-0.8	-1.4	-1.7	-1.6	-1.7	-1.5	-3.7
Comparative body size at age 10	0.8	2.1	5.6	0.4	2.1	1.7	1.6	1.2	1.8	1.8	0.3	2.4	1.3	0.7	1.3	1.8	1.0	-0.2	1.2
Illnesses of father: None of the above (group 1)	0.8	1.0	6.4	-2.5	-1.5	0.4	0.2	-0.6	1.4	0.4	0.6	-0.4	-0.3	-0.4	1.4	0.3	0.8	1.2	0.3
Arm fat mass (left)	0.8	3.2	6.9	0.2	-0.0	-1.1	-2.2	0.8	-1.1	-1.9	-2.3	-1.5	-2.4	-0.7	-2.6	-2.6	-2.0	-1.9	-2.2
Number of self-reported non-cancer illnesses	0.8	1.5	4.4	-0.5	-1.4	-2.1	-1.3	-2.1	-1.1	-0.8	0.4	-2.0	-0.7	-1.2	-0.7	-0.9	-0.8	0.7	-0.5
Hearing aid user	0.8	0.9	2.5	0.6	1.3	1.4	0.5	0.7	0.6	1.2	1.0	1.0	0.6	0.6	1.0	0.3	1.2	0.6	1.6
Pain experienced in last month	0.8	1.3	3.3	-0.9	0.5	1.0	1.6	1.5	1.7	1.8	0.8	1.5	0.7	1.1	0.8	0.4	0.3	1.5	0.6
Reaction Time	0.7	1.4	3.8	0.1	-1.0	-1.8	-1.2	-1.8	-2.0	-1.6	-0.6	-1.4	-1.3	-0.0	-1.1	-1.0	-0.8	-0.5	-0.5
Breast Cancer	0.7	1.6	12.2	0.8	-0.7	-1.1	0.4	-0.8	0.3	-1.1	-0.6	-1.6	0.2	-3.5	0.3	0.9	-1.4	-1.7	-0.0
Lung FVC	0.7	3.6	6.6	-1.3	-2.1	-2.2	-0.5	-0.2	-0.1	-2.3	-2.5	-2.2	-2.4	-1.4	-2.3	-2.6	-2.3	-1.8	-1.7
Average weekly spirits intake	0.7	0.9	3.1	-1.0	-1.8	-1.3	-1.6	-0.2	0.4	-0.1	0.7	-1.3	-0.9	-0.7	-0.9	-0.9	-0.6	0.9	-0.4
Medication: Metformin	0.7	1.0	2.2	-0.0	-0.5	-0.6	-0.7	-0.9	-1.3	-1.1	-1.4	-0.7	-0.8	-0.4	-1.4	-1.1	-1.2	-1.1	-1.5
Diabetes (mother)	0.7	0.8	3.9	-1.4	0.4	0.8	2.0	-0.1	1.2	1.0	0.5	0.5	0.4	1.0	0.6	-0.1	0.4	0.8	1.3
Trunk fat percentage	0.7	2.8	8.4	-0.1	-0.2	-1.2	-2.4	-0.1	-1.5	-1.6	-1.4	-1.6	-2.6	-0.8	-2.3	-2.9	-1.6	-0.9	-1.9
Taking other prescription medications	0.7	1.2	4.1	-0.1	-1.6	-2.0	-1.8	-1.6	-1.4	-1.1	0.4	-1.4	0.2	-0.2	-0.4	0.1	-0.4	0.6	0.1
Age when periods started (menarche)	0.7	1.7	7.6	-0.4	0.7	1.4	0.6	0.5	-0.3	2.2	1.8	1.3	1.0	1.2	1.4	0.3	1.5	2.8	0.1
Qualifications: CSEs or equivalent	0.7	0.9	4.2	1.2	0.3	-0.5	-0.5	0.1	0.1	-1.1	-1.2	-1.1	-0.6	-1.4	-0.6	-0.2	-1.3	-2.0	0.0
Body mass index (BMI)	0.7	2.8	6.6	-0.1	-0.2	-1.1	-2.1	0.4	-0.9	-2.1	-1.8	-1.4	-2.6	-0.8	-2.3	-2.5	-1.8	-1.8	-1.7
Exposure to tobacco smoke at home	0.7	0.8	2.0	1.4	1.4	1.2	1.3	-0.2	-1.1	0.7	-0.7	0.7	0.9	0.0	0.8	0.5	0.6	-0.7	-0.3
Pulse wave reflection index	0.7	0.9	4.7	-1.3	-0.6	-0.0	-0.3	-0.4	-0.2	-0.0	0.2	-0.4	-1.3	2.2	-1.0	-1.7	0.0	0.8	0.3
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.8	1.1	0.4	-0.0	-0.9	0.1	-1.0	-0.5	-1.6	-0.2	-0.2	-1.0	-1.0	-1.0	-0.2	-0.9	-1.9
Body fat percentage	0.7	2.7	7.2	-0.0	-0.2	-1.2	-2.3	-0.1	-1.4	-1.7	-1.3	-1.7	-2.6	-1.0	-2.3	-2.7	-1.6	-1.0	-1.8
Health satisfaction	0.7	0.9	2.9	1.6	1.1	0.3	-1.1	1.0	-0.8	-1.1	-1.5	0.0	-0.1	-0.6	-0.3	0.4	-0.3	-1.7	-0.6
Shortness of breath walking on level ground	0.7	0.8	3.4	0.3	-1.0	-1.0	-0.9	-0.4	-0.3	-1.8	-0.2	-1.3	-0.6	-1.4	-0.3	-0.2	-0.7	-1.2	-0.2
Mouth/teeth dental problems: Loose teeth	0.7	0.9	2.6	-0.8	-0.8	0.9	0.6	0.9	1.1	1.3	-0.3	0.9	1.6	0.8	0.5	0.9	1.2	0.9	-0.3
Overall health rating	0.7	1.6	4.9	2.2	0.0	-0.4	-1.2	0.7	-1.2	-2.1	-1.2	-0.9	-0.2	-1.1	-1.1	-0.7	-0.9	-2.2	-1.4
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.6	-0.2	0.3	-0.3	-0.7	-0.2	-0.6	-1.3	-1.6	-0.1	-1.5	-0.6	-0.7	-0.7	-1.1	-1.1	-1.5
Long-standing illness, disability or infirmity	0.7	1.1	3.4	1.2	0.3	-1.5	-1.5	-1.3	-1.8	-0.7	0.9	-1.0	-0.3	-1.3	-0.8	-0.3	-1.2	0.3	-0.2
Friendships satisfaction	0.7	0.9	3.2	-0.6	-0.1	1.1	1.6	0.5	0.7	0.7	-1.4	0.5	1.8	-0.1	-0.1	1.0	0.4	0.2	-1.5
Asthma (self-reported)	0.7	1.4	6.5	-1.0	-2.6	-2.4	-0.6	-1.9	-0.2	-1.6	-0.0	-1.3	0.1	-0.9	0.0	-0.0	-0.4	0.1	0.6
Wears glasses or contact lenses	0.7	0.8	3.1	1.2	1.3	0.1	-0.0	-0.2	0.5	0.6	1.3	0.2	0.9	0.0	1.0	1.6	0.3	0.0	1.8
Leg fat percentage (left)	0.7	2.5	5.8	-0.2	-0.8	-1.5	-2.1	-0.3	-1.0	-2.1	-1.2	-1.7	-2.4	-1.2	-2.0	-2.2	-1.5	-1.3	-1.5
Schizophrenia (2014)	0.6	1.4	4.4	0.5	0.1	-0.9	-0.6	-0.8	-1.7	-0.9	-1.2	-1.1	-0.8	-1.0	-2.1	-1.4	-1.4	-0.3	-1.8
Angina	0.6	0.8	3.9	-2.0	-1.2	-0.4	0.1	-0.4	0.6	-0.0	1.8	0.1	-0.7	0.4	-0.1	-0.8	0.1	1.3	0.5
Townsend deprivation index at recruitment	0.6	0.9	4.6	-0.7	-2.1	-1.4	-1.3	-1.0	-0.9	-0.8	-0.4	-1.2	-0.0	-0.4	-0.9	-0.3	-0.5	0.3	-0.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	1.9	0.1	-0.2	-0.4	-0.9	-0.1	-0.5	-1.4	-1.0	-0.7	-1.3	-0.1	-1.2	-0.9	-1.0	-1.3	-1.0
High blood pressure (mother)	0.6	0.8	2.4	1.4	0.8	-0.9	-0.9	-1.1	-0.7	-0.5	-0.3	-1.2	-0.5	0.4	-1.5	-0.8	-1.2	-0.6	0.3
Trunk fat mass	0.6	2.7	7.7	-0.1	-0.2	-1.0	-2.3	0.4	-1.4	-1.6	-1.7	-1.4	-2.4	-0.7	-2.3	-2.8	-1.4	-1.2	-2.1
Number of incorrect matches in round	0.6	1.1	2.5	0.1	-0.3	-1.0	-1.1	-0.1	-0.2	-1.6	-1.3	-0.4	-1.2	-1.0	-1.0	-0.9	-1.6	-1.5	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.9	-0.8	-0.3	0.1	1.3	-0.7	1.2	1.0	1.5	0.8	1.5	-0.1	0.3	0.8	0.5	1.7	0.6
Illnesses of siblings	0.6	0.8	3.0	-0.1	-0.7	-0.1	0.7	-0.9	-0.1	-0.3	-1.6	-0.8	0.7	-1.3	-0.3	1.0	-0.8	-1.1	-1.7
Time employed in main current job	0.6	0.7	4.0	0.2	0.4	0.6	0.6	1.0	0.4	-0.6	-1.3	-0.0	-1.0	-0.4	-0.7	-1.0	-0.6	-2.0	-0.5
Mouth/teeth dental problems: Dentures	0.6	0.9	3.9	-0.1	1.6	2.0	0.6	0.8	0.3	1.4	-0.6	1.3	0.1	1.3	-0.0	-0.6	0.3	0.6	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.5	-0.7	-0.8	-1.3	-1.4	-1.6	-0.2	-1.0	-0.4	-1.4	-1.0	-0.6	-0.3	-0.4	-0.5	-0.4	0.6
Pulse wave Arterial Stiffness index	0.6	0.7	4.1	-0.7	-0.6	-0.0	-0.2	0.2	-0.6	-0.1	-0.4	-0.0	-1.1	1.6	-1.4	-2.0	0.0	0.4	-0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.2	0.5	-0.2	-0.9	-1.0	-0.7	-1.5	-0.9	-0.1	-0.9	-0.9	-1.0	-0.4	-1.0	-0.3	-0.4	-0.8
Leg fat percentage (right)	0.6	2.2	4.8	-0.2	-0.8	-1.5	-1.8	-0.3	-1.0	-2.1	-1.0	-1.6	-2.2	-1.4	-1.9	-2.0	-1.5	-1.2	-1.5
Pulse wave peak to peak time	0.6	0.7	4.0	0.9	0.6	0.1	0.2	-0.2	0.3	-0.0	0.2	-0.0	1.1	-1.6	1.2	2.0	-0.0	-0.6	0.1
Eye problems/disorders: None of the above	0.6	0.7	2.0	-1.4	-1.2	0.1	0.3	-0.9	0.9	0.7	0.5	0.4	0.7	1.1	0.0	0.6	0.7	1.0	1.0
Whole body fat mass	0.6	2.3	6.2	0.1	0.1	-0.8	-2.1	0.5	-1.3	-1.5	-1.6	-1.3	-2.3	-0.7	-2.2	-2.5	-1.4	-1.2	-1.9
Leg fat mass (right)	0.6	2.2	4.9	-0.2	-0.5	-1.1	-1.9	0.3	-0.9	-1.9	-1.7	-1.3	-2.1	-1.0	-2.1	-2.2	-1.3	-1.5	-1.8
Pulse rate, automated reading	0.6	1.9	5.0	0.7	-1.0	-1.7	-2.0	-0.5	-1.3	-1.3	-1.5	-1.3	-1.0	-1.2	-1.4	-1.6	-1.3	-1.1	-2.2
Ever had bowel cancer screening	0.6	0.7	4.0	0.0	-0.8	-0.8	-0.8	0.7	-0.1	-0.8	-1.0	-0.4	0.0	-1.2	-0.5	-0.3	-0.9	-0.5	-2.0
Osteoporosis (self-reported)	0.6	0.8	2.0	0.8	-1.0	-1.1	-1.1	-1.0	-0.8	0.0	0.1	-0.4	1.4	-0.6	-1.2	0.8	-0.8	0.8	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	4.8	-0.5	-0.8	-0.8	-0.4	1.0	0.2	-0.5	-2.2	-0.3	-0.7	0.1	-1.9	-1.1	-1.6	-1.4	-2.0
Guilty feelings	0.6	0.9	4.6	-1.0	-0.8	0.6	2.1	-0.6	1.1	0.5	0.3	-0.0	1.3	-0.2	1.3	1.2	1.0	0.6	0.1
Ever taken oral contraceptive pill	0.6	0.7	2.9	1.2	1.7	0.5	-0.4	-0.5	-0.7	0.8	0.5	0.1	0.6	-1.2	1.1	1.1	0.2	0.4	-0.5
Financial situation satisfaction	0.6	0.8	3.4	-1.5	-1.8	-1.0	-0.5	-1.1	0.2	-0.9	-0.6	-1.0	-0.1	-1.2	-0.3	0.1	-0.5	0.1	-0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.1	-0.4	-0.4	-0.0	-0.2	1.1	1.0	0.6	1.5	1.3	1.0	0.5	0.6	1.1	0.8	1.3	0.9
Ever smoked	0.6	1.0	4.1	-0.1	-0.0	1.3	0.8	2.0	1.2	0.9	-0.7	1.0	1.7	0.7	0.8	0.9	1.0	-0.4	0.4
Basal cell carcinoma (self-reported)	0.6	0.7	3.3	-0.2	1.0	0.1	0.5	-0.6	-0.4	1.0	1.5	-0.2	-0.1	0.2	0.8	0.2	0.6	1.8	1.6
Leg fat mass (left)	0.6	2.2	5.2	-0.2	-0.5	-1.0	-2.0	0.4	-0.9	-1.8	-1.7	-1.2	-2.2	-0.8	-2.0	-2.3	-1.3	-1.5	-1.8
BMI	0.5	2.9	6.0	0.5	0.2	-0.8	-2.4	0.3	-1.5	-1.9	-2.2	-1.0	-2.4	-0.9	-1.9	-2.4	-1.7	-2.1	-2.2
Hypothyroidism (self reported)	0.5	1.1	2.8	-1.2	0.0	0.9	0.4	0.2	0.6	1.4	1.7	0.8	0.3	1.1	1.5	0.4	1.4	1.5	1.2
Ever had hysterectomy (womb removed)	0.5	0.6	1.8	-0.5	0.1	0.5	1.4	-0.2	0.9	0.6	0.9	1.1	0.5	1.3	-0.1	0.2	0.4	1.1	0.8
Pack years adult smoking proportion	0.5	0.8	4.0	-0.3	-1.4	-0.4	0.2	-0.9	-0.1	-0.9	-0.7	-0.7	-0.4	-2.0	-0.6	-0.5	-0.5	-1.0	-1.4
Supplements: Glucosamine	0.5	0.7	2.7	-1.2	-1.2	-0.5	0.1	1.6	0.8	-0.8	-1.1	-0.0	0.0	-1.0	0.1	0.4	-0.5	-0.7	-0.7
Waist circumference	0.5	1.9	4.7	-0.2	-0.6	-0.8	-1.7	0.7	-0.6	-1.7	-1.5	-1.2	-2.0	-0.6	-1.7	-2.2	-1.2	-1.5	-1.7
Hair/balding pattern: Pattern 2	0.5	0.7	1.4	-0.6	-0.2	1.2	1.2	0.6	0.9	0.7	-0.4	0.3	1.1	1.1	0.5	1.1	1.0	-0.1	0.8
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	2.8	-1.1	-0.7	0.2	0.2	1.0	0.4	0.4	-1.1	0.8	-0.2	0.2	-1.1	-1.2	-0.0	0.4	-1.7
Heart attack	0.5	0.7	2.0	1.0	1.4	0.3	-0.3	0.9	-0.5	-0.2	-0.4	-0.5	-0.9	-1.0	-0.5	-1.0	-0.8	-0.7	-1.2
Medication: Simvastatin	0.5	0.7	3.2	1.5	1.0	0.1	-0.1	0.8	-0.6	-0.1	-0.7	0.3	-0.6	-0.2	-0.9	-0.9	-1.2	-0.6	-1.8
Weight	0.5	2.3	6.0	-0.1	-0.2	-0.5	-1.7	1.1	-0.7	-1.5	-2.2	-0.9	-2.0	-0.5	-2.0	-2.4	-1.3	-1.6	-2.5
Medication: Lansoprazole	0.5	0.6	2.7	-1.6	-0.1	0.3	-0.4	0.0	1.4	0.9	0.8	0.8	0.5	-0.0	0.3	0.8	0.0	1.4	0.1
Medication: Ventolin 100micrograms inhaler	0.5	0.6	3.0	0.3	-1.3	-1.7	-0.9	-0.6	-0.9	-1.1	-0.4	-0.3	0.6	-0.1	-0.9	0.1	-0.6	-0.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.3	1.5	0.8	-0.6	-0.1	0.2	-0.2	-0.3	-0.2	-0.9	-0.2	-0.7	-1.4	-0.3	-1.4	-0.8	-0.5
Medication: Blood pressure	0.5	0.8	5.2	2.1	2.3	0.8	0.0	0.4	-1.0	0.4	0.3	0.4	0.3	-0.1	0.5	0.5	0.4	-0.3	0.3
Angina (self-reported)	0.5	0.7	3.0	-1.7	-1.1	-0.5	-0.1	-0.3	0.5	-0.2	1.5	0.0	-1.0	0.3	-0.3	-1.2	-0.2	1.0	0.1
Illnesses of father: Heart disease	0.5	0.7	3.3	0.3	-0.2	-1.8	-0.5	-1.1	-0.8	-0.9	0.6	-1.0	-0.5	-0.5	-0.8	-0.5	-0.6	0.3	1.0
Illnesses of siblings: Diabetes	0.5	0.6	5.0	0.5	-0.1	-0.3	-0.1	0.4	0.6	0.1	1.1	0.6	-0.1	0.8	0.1	-0.5	0.6	0.1	2.2
Commuting to job workplace: Walk	0.5	0.5	2.1	-0.3	-0.9	-0.3	-1.1	-0.6	-0.1	-0.1	-1.3	-0.5	-0.3	-0.1	-0.5	-0.5	-0.6	-0.5	-1.4
Medication for cholesterol	0.5	0.7	2.4	0.1	0.6	-0.5	-1.2	-1.3	-0.8	-0.0	0.7	-1.4	-0.9	-1.5	0.7	0.1	-0.2	-0.0	1.1
Medication: Bendroflumethiazide	0.5	0.8	2.8	0.6	-0.2	0.3	0.5	1.3	0.9	0.1	0.4	0.7	1.4	1.7	0.4	1.3	0.9	0.1	1.1
Ever depressed for a whole week	0.5	0.6	2.5	-1.3	-0.2	0.8	0.6	1.0	1.6	0.7	-0.9	0.8	0.1	0.3	-0.3	-0.2	0.1	0.0	-1.0
Myopia	0.5	0.7	2.0	-0.2	-0.1	-0.2	-0.7	-1.3	-0.7	-0.3	-1.1	-0.8	-0.9	-0.4	-0.9	-1.2	-0.7	-0.3	-1.4
Cholesterol lowering medication	0.5	0.7	2.7	1.2	0.9	-0.2	-1.0	0.8	0.2	-0.0	0.3	0.3	-0.5	-0.5	-1.6	-0.6	-1.5	-0.5	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.7	-1.6	-1.4	-0.8	-0.1	-0.3	0.7	-0.9	-0.4	-0.9	-1.0	-0.8	0.2	0.2	-0.4	-0.4	-0.1
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.6	0.9	1.6	0.5	-0.3	0.9	-0.4	-0.0	-0.3	-0.4	-1.0	-1.0	-0.4	-1.0	-0.8	-0.6	-1.1
Bipolar Disorder or Schizophrenia	0.4	1.0	3.9	0.6	0.3	-0.3	-0.2	0.8	-0.9	-0.6	-1.6	0.0	-0.3	-0.6	-1.7	-0.9	-1.3	-0.9	-2.0
Depression (Nagel 2018)	0.4	0.7	2.0	-0.6	-0.6	-0.0	1.3	0.0	1.1	0.0	1.0	0.8	1.2	0.4	0.1	1.1	0.4	0.4	1.4
Age at First Birth	0.4	0.6	1.7	-0.3	-1.3	-0.7	0.0	-0.6	-0.5	-1.1	-0.5	-1.2	-0.6	-1.2	-0.4	-0.3	-0.9	-0.9	-0.8
Neuroticism (2016)	0.4	0.6	1.7	-0.3	0.2	0.4	-0.0	0.4	0.7	1.0	0.4	1.2	1.2	-0.5	1.3	1.1	0.3	0.9	-0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.5	1.0	1.1	0.7	-0.3	0.9	0.0	1.2	0.9	0.6	-0.4	1.1	-0.1	-0.7	0.3	0.5	-0.2
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.2	-0.5	-0.3	-0.5	-0.3	-0.0	-1.1	-1.2	-0.8	-0.5	-1.5	0.3	-1.2	-1.3	-1.1	-1.0	-0.8
Hearing difficulty/problems: Yes	0.4	0.6	1.4	0.7	0.7	0.4	0.8	0.4	0.8	0.7	1.1	0.0	0.8	-1.1	1.2	1.2	0.4	0.6	0.5
Vitamin and mineral supplements	0.4	0.5	2.2	0.3	0.9	0.6	-0.4	-0.1	-1.5	0.2	-0.1	0.5	-0.9	1.4	-0.6	-1.2	0.0	-0.4	0.2
Severe depression (siblings)	0.4	0.4	1.4	0.5	0.2	-0.9	-0.2	0.0	-0.3	-0.7	0.2	-0.8	-0.7	-0.4	-1.0	-0.8	-1.2	-0.6	0.4
Leg fat-free mass (left)	0.4	1.9	7.6	-0.1	0.2	0.3	-1.0	1.8	-0.4	-0.8	-2.8	-0.1	-1.2	0.4	-1.6	-2.0	-0.7	-1.9	-2.5
Relative age voice broke	0.4	0.6	1.7	0.8	-0.2	-0.1	-0.8	0.5	-1.3	-0.8	-0.9	1.1	0.9	1.0	-1.1	-0.2	-0.0	-0.5	-0.8
Multivitamins +/- minerals	0.4	0.5	3.2	-0.0	-0.8	-1.1	-0.3	-0.3	0.8	-0.8	0.1	-0.9	-0.1	-1.8	-0.6	-0.3	-0.6	0.4	-0.4
Leg predicted mass (left)	0.4	2.0	7.7	-0.0	0.2	0.2	-1.1	1.7	-0.5	-0.9	-2.8	-0.1	-1.2	0.4	-1.7	-2.0	-0.8	-1.9	-2.5
Qualifications: None of the above	0.4	0.9	2.5	-0.7	-1.3	0.9	0.1	1.2	0.8	0.1	-0.0	1.6	1.1	0.9	1.0	1.4	1.0	-0.5	0.7
Fluid intelligence score	0.4	0.8	3.0	-0.1	0.0	-1.3	-0.8	-1.5	0.3	-0.4	-0.1	-1.4	-0.7	-1.7	-0.5	-0.4	-1.4	0.0	-0.7
Hip circumference	0.4	1.8	4.9	0.6	0.4	0.1	-1.3	1.5	-0.5	-1.0	-2.2	-0.4	-1.4	-0.4	-1.6	-1.9	-0.9	-2.0	-2.2
Exposure to tobacco smoke outside home	0.4	0.6	1.7	0.9	0.6	1.2	0.9	0.3	-0.9	0.3	-0.3	0.6	0.5	1.2	0.7	-0.2	1.3	-0.8	0.2
Age at first live birth	0.4	0.7	2.0	-0.7	-0.2	0.9	0.7	0.8	0.3	0.7	0.4	1.2	0.4	1.3	1.1	0.8	1.4	0.7	-0.0
Qualifications: College or University degree	0.4	1.4	6.6	-0.4	1.4	-0.0	0.8	-1.0	0.1	1.2	2.6	-0.3	-0.2	-0.0	1.1	0.6	0.2	1.8	2.2
Mean time to correctly identify matches	0.4	0.7	1.9	-0.5	-1.2	-1.4	-0.4	-1.0	-0.9	-1.2	0.3	-1.2	-1.1	0.1	-0.7	-0.6	-0.7	0.1	0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.5	-0.4	-1.1	-0.7	-0.7	-0.6	0.3	-1.1	-1.2	-0.7	-0.6	-0.9	0.1	-0.5	-0.1	-0.8	-0.1
Arm predicted mass (right)	0.4	1.9	6.1	0.2	-0.0	-0.0	-1.2	1.5	-0.3	-1.0	-2.5	-0.4	-1.3	-0.4	-1.7	-2.0	-1.1	-1.8	-2.4
Suffer from ‘nerves’	0.4	0.6	1.8	-0.6	-0.8	0.2	1.4	-0.0	0.5	0.6	1.1	0.6	1.1	0.4	0.4	0.5	1.0	1.2	0.3
Had major operations	0.4	0.4	1.8	-0.1	0.0	0.7	0.8	0.3	-0.0	0.4	-0.6	0.8	1.3	0.8	0.6	0.4	1.3	-0.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.7	-0.9	-0.1	-0.9	0.1	-0.5	0.4	-0.5	0.8	-1.1	-1.3	-0.7	-0.1	0.0	-0.9	0.7	0.4
Smoking status: Previous	0.4	0.5	1.7	-0.1	-0.8	-0.9	-1.3	0.3	-0.8	-0.9	-0.6	-1.0	-0.6	-0.8	-0.4	-0.7	-0.7	-0.4	-0.4
Leg fat-free mass (right)	0.4	2.2	8.8	0.1	0.0	0.2	-1.3	1.6	-0.5	-1.0	-3.0	-0.2	-1.2	0.4	-1.7	-2.1	-0.8	-2.0	-2.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.4	1.1	1.1	0.7	0.8	-0.1	0.2	0.8	0.2	-0.2	0.8	-0.0	0.9	1.2	0.4	-0.1	0.4
Mood swings	0.4	0.6	2.5	-0.5	-0.1	0.6	1.6	0.8	1.2	0.8	0.3	1.0	1.3	-0.3	0.5	1.1	0.4	0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.8	0.9	1.2	0.5	-1.0	-0.2	-0.8	1.0	0.2	1.0	0.4	1.4	-0.9	-0.2	0.0	0.5	-0.3
Breast cancer (self-reported)	0.4	0.5	2.5	-0.4	-0.2	-0.3	-0.8	-0.4	-1.0	-0.4	0.0	-0.3	-1.6	0.3	-0.2	-1.4	0.1	0.1	-0.8
Osteoarthritis (self-reported)	0.4	0.5	1.9	-0.9	-0.6	-1.0	-0.6	-0.5	0.3	-1.1	0.1	-0.7	-1.1	-1.4	0.0	-0.3	-0.7	-0.3	-0.1
Medication: Aspirin	0.4	0.5	2.4	0.4	0.9	0.4	-0.3	1.4	0.0	-0.0	-0.5	0.3	-1.0	-0.6	-0.4	-0.7	-0.6	-0.5	-1.5
Leg predicted mass (right)	0.4	2.0	8.4	0.1	0.1	0.3	-1.2	1.7	-0.5	-0.9	-2.9	-0.1	-1.2	0.4	-1.6	-2.0	-0.7	-1.9	-2.5
Medication: Blood pressure	0.4	0.7	2.4	-0.8	-1.4	-0.2	0.2	1.1	0.1	-0.7	-0.6	0.5	-0.5	1.5	-1.3	-1.0	0.1	0.4	-1.2
Medication: Paracetamol	0.4	0.5	2.6	-1.2	-0.8	-0.9	-0.4	-1.6	0.6	-0.2	0.7	-0.3	-0.3	-0.4	0.4	0.2	0.4	0.5	1.0
Alcohol drinker status: Never	0.4	0.4	1.7	0.4	0.8	-0.0	-0.4	0.8	0.7	0.5	1.1	0.4	0.7	-0.2	-0.0	1.3	-0.2	0.5	0.7
Irritability	0.4	0.6	1.4	0.8	1.2	-0.3	-0.5	0.2	-0.8	-0.6	-0.2	-0.8	-1.0	-1.1	-1.0	-1.0	-1.2	-0.7	-0.1
Fractured/broken bones in last 5 years	0.4	0.5	1.0	-0.6	-0.8	-0.0	0.8	0.0	0.2	0.7	0.8	0.9	1.0	0.7	0.1	0.8	0.7	1.0	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.1	0.1	0.8	0.8	-0.1	0.3	0.2	1.0	0.7	0.7	0.8	1.0	0.7	1.1	0.8	0.9	1.0
Alcohol drinker status: Previous	0.4	0.4	1.4	0.8	0.7	0.5	0.5	0.2	0.8	-0.3	-0.1	-0.6	0.2	-0.8	0.8	1.2	-0.1	-0.8	0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	2.4	-0.3	0.1	-0.1	0.1	-0.0	0.7	0.8	1.3	-0.1	0.0	0.5	0.1	-0.4	0.5	1.5	0.6
Alzheimer’s Disease (in father)	0.3	0.4	1.4	0.0	-0.6	-0.6	-0.2	-0.1	-0.3	-0.7	-1.1	0.1	-0.3	0.1	-0.9	-0.6	-0.4	-0.7	-1.2
Mean Putamen Volume	0.3	0.3	1.0	0.7	-0.4	-0.3	0.5	0.1	-0.0	-0.2	1.0	0.2	0.8	0.7	0.1	0.1	0.9	0.5	0.8
LDL Cholesterol	0.3	0.4	1.7	0.6	0.5	0.3	0.0	1.1	-0.0	0.8	-0.7	0.9	1.3	0.5	0.6	0.6	0.8	-0.1	-0.3
Blood White Count	0.3	2.1	5.8	0.9	-0.9	-1.8	-1.2	-1.0	-2.0	-2.4	-1.5	-1.2	-0.8	-0.1	-1.8	-1.7	-1.2	-1.9	0.2
Cardiovascular Disease	0.3	1.0	3.4	1.3	0.8	-0.7	-1.7	0.1	-1.8	-0.3	-0.5	-0.2	-1.0	-0.0	-1.3	-0.8	-1.0	-0.8	-1.5
Sensitivity / hurt feelings	0.3	0.5	2.0	-1.2	-1.4	-0.5	0.2	-0.9	-0.6	-0.4	0.2	-0.3	0.4	-0.3	-0.6	0.2	0.2	1.1	-0.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.3	0.5	0.5	0.7	0.8	1.2	0.4	0.2	-0.0	0.1	-0.1	0.1	-0.6	-0.7	-0.3	0.1	-1.1
Hand grip strength (right)	0.3	0.7	3.0	-0.6	-0.3	0.5	0.6	1.6	1.3	0.0	-1.7	0.6	0.2	-0.4	-0.3	-0.3	-0.2	-0.8	-1.0
Medication: Levothyroxine sodium	0.3	0.5	2.1	-1.2	-0.7	0.2	0.1	-0.5	0.9	0.1	1.5	0.3	-0.1	0.6	0.4	0.1	0.2	1.0	0.9
Had other major operations	0.3	0.4	1.4	1.2	0.8	0.5	0.2	0.7	-0.7	-0.2	-0.4	0.5	0.0	1.1	-0.3	-0.1	0.3	-0.9	0.2
Forced vital capacity (FVC)	0.3	1.2	5.8	-0.9	-1.3	-0.7	0.3	0.4	-0.2	-0.8	-2.4	-0.8	-0.4	-0.5	-1.1	-1.1	-0.9	-0.9	-2.0
Financial difficulties in last 2 years	0.3	0.4	2.0	0.1	-1.4	-1.4	-0.9	-0.6	-0.5	-0.4	0.9	-0.8	-0.1	-0.1	0.0	-0.0	0.1	0.4	0.3
Medication: Ramipril	0.3	0.4	2.3	0.5	-0.3	-0.7	-1.1	0.2	-0.4	-0.5	-0.3	-0.5	-0.6	-0.0	-0.8	-0.8	-0.4	0.0	-1.5
Neuroticism score	0.3	0.6	2.0	-0.6	0.1	0.5	1.4	-0.4	0.4	0.8	1.2	0.1	0.8	0.0	0.5	0.7	0.8	1.4	0.9
Number of live births	0.3	0.4	2.0	1.2	-0.3	-0.8	0.2	-0.2	-0.5	-0.7	0.1	-0.2	1.4	-0.9	-0.6	0.4	-0.5	-0.3	0.3
Depression (self-reported)	0.3	0.4	1.8	-0.8	-1.4	-0.3	1.2	0.1	0.4	-0.2	-0.6	-0.1	0.7	0.7	-0.3	-0.0	0.6	-0.1	0.4
Length of working week for main job	0.3	0.3	1.8	0.5	1.4	0.3	0.2	-0.3	-0.9	0.2	0.2	-0.1	-0.9	0.5	-0.3	-0.7	-0.1	0.0	0.2
Breastfed as a baby	0.3	0.3	0.8	-0.7	-0.8	-0.5	-0.6	0.4	0.5	-0.6	-0.3	0.3	0.2	-0.4	-0.9	-0.2	-0.9	-0.1	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	2.5	0.8	0.1	0.2	0.8	0.4	0.6	0.4	-0.1	0.5	1.6	0.3	-0.3	1.1	-0.0	-0.5	-0.2
Hair/balding pattern: Pattern 4	0.3	0.7	3.8	0.4	0.1	-0.7	0.2	-1.2	-0.9	-0.0	1.7	-0.7	-0.5	-0.0	-0.1	-0.6	-0.0	0.6	2.0
Medication: Paracetamol	0.3	0.6	3.3	-1.1	-0.8	-0.9	-0.5	-1.8	0.4	-0.5	0.6	-0.1	-0.3	-0.1	0.0	0.2	0.3	0.3	1.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.7	-0.5	0.7	0.8	0.3	0.2	0.7	1.1	1.3	0.8	0.4	0.4	0.9	0.3	0.6	0.8	0.8
Arm fat-free mass (right)	0.3	1.7	6.6	0.2	0.1	0.3	-0.8	2.0	0.0	-0.9	-2.6	0.0	-1.0	-0.1	-1.5	-1.7	-0.8	-1.9	-2.3
Migraine (self-reported)	0.3	0.4	1.4	-1.0	-1.2	-0.5	0.1	-0.9	-0.6	-0.7	-0.3	-0.0	0.3	-0.0	0.4	1.1	0.4	0.2	-0.3
Medication: Ibuprofen	0.3	0.4	1.9	-0.9	-0.6	-0.5	-0.6	-1.2	0.3	0.0	0.2	-0.5	-0.0	0.4	0.6	0.3	0.6	0.3	1.4
Medication: Aspirin	0.3	0.5	3.1	0.4	0.4	0.3	-0.4	1.1	-0.4	-0.0	-0.3	0.5	-0.7	-0.4	-0.6	-0.8	-0.4	-0.2	-1.8
Hypertension (Self-reported)	0.3	0.8	2.2	1.1	0.9	-0.4	-0.6	0.6	-1.3	-0.4	-0.4	-0.3	-1.2	0.2	-1.4	-1.5	-0.6	-0.1	-1.2
Whole body fat-free mass	0.3	1.8	6.8	0.2	0.4	0.5	-0.7	2.0	-0.1	-0.7	-2.6	0.1	-1.1	0.2	-1.3	-1.8	-0.7	-1.9	-2.4
Eye problems/disorders: Cataract	0.3	0.3	1.7	0.2	-0.7	-0.4	-0.1	0.2	-1.1	-0.3	-0.5	0.2	0.5	-0.1	-0.2	-0.7	-0.0	0.2	-1.3
Whole body water mass	0.3	1.4	6.1	0.1	0.4	0.7	-0.5	1.9	0.0	-0.5	-2.5	0.2	-0.8	0.4	-1.1	-1.5	-0.5	-1.7	-2.1
Medication: Atorvastatin	0.3	0.3	2.1	-0.9	-1.5	-0.3	-0.2	-0.4	-0.5	-0.9	0.5	-0.4	-0.3	0.4	-0.1	0.0	0.2	0.1	-0.1
Basal metabolic rate	0.3	1.8	6.6	0.1	0.2	0.3	-1.0	1.7	-0.3	-0.9	-2.6	-0.2	-1.3	0.0	-1.5	-1.9	-0.9	-1.9	-2.4
Arm fat-free mass (left)	0.3	1.3	5.1	-0.2	0.0	0.4	-0.5	1.8	0.1	-0.6	-2.3	0.1	-0.9	0.2	-1.4	-1.6	-0.7	-1.4	-2.1
Number of operations (self-reported)	0.3	0.4	1.2	-0.2	0.1	0.8	0.7	0.2	0.4	0.2	-0.2	0.8	0.8	0.3	1.1	0.8	1.0	-0.6	0.4
Risk taking	0.3	0.5	2.8	-0.4	-1.7	-1.1	-0.4	-0.9	-0.5	-1.2	0.0	-0.6	0.2	-0.4	-0.1	0.2	0.3	0.3	0.3
Pack years of smoking	0.3	0.5	2.9	-0.5	-1.3	0.1	0.5	-0.3	0.3	-0.5	-0.4	-0.0	-0.1	-1.7	-0.2	-0.2	-0.1	-0.7	-1.3
Arm predicted mass (left)	0.3	1.3	4.9	-0.1	0.0	0.3	-0.5	1.7	-0.1	-0.7	-2.2	-0.0	-0.9	0.0	-1.4	-1.6	-0.7	-1.4	-2.2
Neuroticism (Nagel 2018)	0.2	0.4	2.3	-0.9	-0.3	-0.1	1.5	-0.1	0.6	-0.2	-0.1	-0.5	0.3	-1.5	0.1	0.4	-0.5	0.1	-0.4
Schizophrenia (2018)	0.2	0.3	1.9	-0.5	-0.3	-0.4	0.1	0.4	-0.4	-0.3	-0.8	-0.0	-0.2	0.0	-1.4	-1.0	-0.6	0.2	-0.7
Worry (Nagel 2018)	0.2	0.3	2.4	-0.7	-0.8	-0.0	1.5	-0.0	0.7	-0.3	0.1	-0.5	0.2	-0.6	0.0	0.2	-0.2	0.4	-0.5
Ovarian Cancer	0.2	0.3	1.1	-0.5	-1.1	-0.2	1.0	-0.6	-0.1	-0.8	-0.2	0.4	0.4	0.4	-0.3	0.1	0.1	-0.4	0.6
Body Mass Index (BMI) (2010)	0.2	0.3	1.0	0.5	1.0	0.2	0.6	-0.0	0.9	0.3	0.4	-0.4	-0.5	0.2	0.1	0.5	-0.4	-0.2	0.6
HDL Cholesterol	0.2	0.3	1.0	0.9	0.2	-0.2	-0.4	-0.3	-1.0	-0.5	-0.4	-0.6	-0.5	-0.3	-0.2	-0.6	-0.3	-0.4	-0.7
Lupus	0.2	0.4	2.1	-0.7	-1.5	-0.4	-0.3	0.9	0.1	-0.7	0.6	0.3	0.0	-0.1	0.5	0.5	0.7	-0.2	0.6
Blood Platelet Count	0.2	2.0	10.2	3.0	3.2	1.4	-0.2	0.6	-1.8	0.6	-0.2	0.7	-0.1	1.7	-1.1	-0.6	0.1	-1.0	-0.2
Height	0.2	3.6	10.8	0.3	1.1	3.2	1.9	3.1	0.8	1.8	-0.3	3.3	1.7	2.9	1.0	0.9	2.3	0.4	-0.5
Smoking Status	0.2	0.4	1.3	-0.7	-1.0	-0.4	-0.1	0.3	0.5	-0.5	-1.1	0.0	0.8	-1.1	0.3	0.5	-0.3	-1.0	-0.2
Lung FEV1/FVC ratio	0.2	0.9	3.0	1.0	0.8	0.3	-0.1	0.6	-1.1	-0.2	-1.5	-0.5	-1.0	0.0	-1.3	-1.2	-0.7	-1.3	-1.7
Chronotype (morning person)	0.2	0.5	2.2	-0.0	0.1	0.4	0.3	-0.9	0.9	-0.0	-0.2	0.5	1.1	0.2	0.8	1.5	0.2	-1.0	0.6
Hand grip strength (left)	0.2	0.5	1.3	-1.0	-0.1	0.8	1.0	0.6	0.9	1.0	-0.1	1.1	0.4	0.8	0.2	0.2	0.6	0.9	-0.2
Number of treatments/medications taken	0.2	0.3	1.3	-0.3	-1.1	-0.9	-0.3	-0.7	0.2	-0.6	-0.3	-0.2	0.6	-0.3	0.3	0.7	-0.0	0.2	-0.6
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.5	-0.2	-0.5	-0.3	0.1	0.2	0.4	-0.2	-0.0	1.0	1.2	0.0	-0.5	0.6	-0.1	0.2	0.1
Systolic blood pressure, automated reading	0.2	0.5	1.4	-0.9	0.0	0.6	0.6	0.8	0.3	-0.5	0.1	1.0	-0.9	1.2	-0.3	-1.2	0.4	0.2	0.4
Impedance of leg (right)	0.2	0.8	3.5	0.5	-0.4	-0.6	0.3	-1.9	-0.7	0.1	1.5	-0.8	0.4	-1.4	0.4	0.9	0.0	1.0	0.5
Maternal smoking around birth	0.2	0.3	1.3	-0.2	0.3	-0.1	-0.4	-0.6	-0.5	-0.1	0.1	-0.9	-0.7	-0.8	1.1	0.1	0.5	-0.4	0.2
High blood pressure	0.2	0.6	1.7	1.1	0.9	-0.4	-0.5	0.5	-1.1	-0.1	-0.3	-0.2	-0.8	-0.1	-1.3	-1.2	-0.6	-0.1	-1.2
Impedance of leg (left)	0.2	0.9	5.0	0.5	-0.7	-0.9	-0.2	-2.2	-0.8	-0.1	1.3	-1.1	0.1	-1.5	0.2	0.5	-0.2	0.9	0.5
Past tobacco smoking	0.2	0.4	2.3	-0.1	0.4	-0.2	0.6	-1.5	0.1	0.1	1.2	0.1	-0.5	0.6	-0.2	0.1	0.1	0.9	0.7
Hearing difficulty/problems with background noise	0.2	0.4	1.9	0.3	-0.2	-0.3	1.1	-0.0	0.8	0.2	-0.6	-0.8	0.4	-1.4	0.4	0.3	-0.3	-0.4	-0.3
Trunk fat-free mass	0.2	1.1	4.1	0.2	0.4	0.6	-0.3	1.8	0.2	-0.5	-2.0	0.2	-0.9	0.1	-0.8	-1.3	-0.6	-1.6	-1.8
Worrier / anxious feelings	0.2	0.4	1.4	-0.6	-0.6	-0.5	0.5	-0.4	0.3	-0.8	0.7	-0.8	-0.8	-1.2	-0.3	-0.0	-0.6	0.2	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.8	0.9	0.2	-0.4	0.5	0.5	0.3	-0.7	0.0	0.3	0.6	-0.6	-0.8	0.2	-0.3	-0.8	0.1
Falls in the last year	0.2	0.3	1.0	0.9	0.1	-0.9	-0.5	-0.1	-0.3	-1.0	-0.1	-0.5	-0.5	-0.6	-0.2	0.3	-0.5	-1.0	0.1
Hair/balding pattern: Pattern 3	0.2	0.4	1.1	0.3	1.0	0.1	-0.3	0.5	-1.0	0.1	0.4	0.1	-0.8	0.7	-0.3	-1.0	0.1	0.6	-0.7
Qualifications: A levels/AS levels or equivalent	0.2	0.5	3.0	0.6	1.7	0.1	-0.1	0.0	0.3	0.5	0.6	0.3	-0.0	-0.2	0.5	1.1	-0.6	0.2	1.1
Medication: Cholesterol lowering	0.2	0.3	1.7	0.2	-0.1	-0.3	0.1	-0.7	-1.3	-0.7	-0.4	-0.1	-0.7	0.2	-0.0	-0.3	-0.3	-0.2	-0.6
Lung cancer (father)	0.2	0.2	1.1	1.0	0.2	-0.2	-0.9	0.4	-0.3	-0.3	0.2	-0.0	-0.2	-0.0	-0.3	-0.1	-0.6	-0.6	-0.5
Trunk predicted mass	0.2	1.0	3.8	0.1	0.5	0.7	-0.2	1.8	0.3	-0.4	-2.0	0.3	-0.8	0.1	-0.8	-1.2	-0.5	-1.5	-1.8
Tense / ‘highly strung’	0.2	0.3	1.0	0.1	0.0	0.5	0.5	0.1	-0.6	0.5	0.4	0.1	0.7	0.1	0.0	-0.2	0.8	1.0	-1.0
Medication: Amlodipine	0.2	0.3	1.0	-0.6	-0.9	-0.1	0.2	0.2	-0.5	-1.0	-0.8	0.3	-0.2	0.7	-1.0	-0.5	0.2	-0.2	-0.5
Birth weight	0.2	0.4	1.8	0.6	-0.4	-0.2	-1.0	0.1	-0.4	-0.5	-0.9	0.1	0.3	-0.4	-0.8	-0.6	-0.6	-0.5	-1.3
Medication: Seretide 50 evohaler	0.2	0.2	0.9	0.2	0.1	0.5	0.0	-0.2	0.7	0.1	-0.1	0.5	0.5	0.5	0.8	0.9	0.5	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	3.1	0.6	-0.2	-0.2	-0.5	0.1	-0.3	0.2	-1.7	-0.2	0.9	-1.0	0.3	0.5	0.0	-0.9	-0.8
Loneliness, isolation	0.2	0.3	1.6	0.5	1.3	0.8	0.2	-0.1	-0.0	0.3	-0.3	0.5	0.2	0.4	-0.1	0.2	0.2	-0.8	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.3	-0.6	-1.2	-0.5	0.2	-0.4	-0.1	-0.1	-0.0	-0.4	0.2	0.3	-0.1	0.0	0.1	0.4	0.6
Mineral and other dietary supplements	0.2	0.3	1.3	-0.3	0.4	1.1	0.8	0.1	-0.1	0.4	-0.8	0.1	-0.3	0.9	-0.1	-0.7	0.3	-0.4	-0.4
Medication: Gliclazide	0.2	0.2	1.2	0.1	0.6	0.4	1.1	-0.3	-0.1	-0.0	-0.7	-0.2	-0.3	0.2	-0.0	-0.4	-0.2	-0.5	0.0
Miserableness	0.2	0.4	1.8	-0.2	-0.8	-1.4	-0.3	-0.8	-0.3	-0.4	0.4	-0.8	0.6	-1.0	-0.3	0.1	-0.5	0.5	0.8
High cholesterol (Self-reported)	0.2	0.3	1.4	0.1	-0.2	0.5	0.1	1.0	-0.2	0.2	-0.2	1.0	0.1	1.0	-0.7	-0.2	-0.2	0.2	-1.2
Medication: Lisinopril	0.2	0.2	0.7	-0.1	0.5	0.8	0.6	-0.2	-0.7	0.2	-0.3	0.1	-0.6	0.8	0.2	-0.2	0.6	-0.5	-0.2
Illnesses of father: High blood pressure	0.2	0.2	0.6	0.8	0.0	-0.6	-0.2	-0.3	-0.8	-0.1	0.4	-0.2	0.6	-0.2	-0.1	0.5	0.4	0.4	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.1	-0.0	0.7	-0.2	-0.7	0.3	-0.1	0.3	0.1	-0.1	-1.1	-0.2	-0.5	-0.8	-0.6	-0.0	-0.3
Diastolic blood pressure, automated reading	0.2	0.6	1.9	-1.2	0.0	-0.3	-0.0	0.2	0.1	-0.4	0.7	0.1	-1.4	1.4	-0.7	-1.4	0.2	0.7	0.9
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.4	-1.2	-1.1	0.3	0.6	-0.4	1.2	-0.0	-0.2	0.2	0.8	0.2	1.1	1.1	0.6	-0.1	1.1
Depressed Affect (Nagel 2018)	0.1	0.2	0.6	-0.2	0.1	-0.3	0.6	0.1	0.1	-0.3	-0.8	0.1	0.3	-0.7	-0.5	-0.0	-0.8	-0.6	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.0	-1.0	-0.3	-0.3	0.9	-0.8	0.7	0.7	0.3	0.3	0.2	0.6	0.4	0.1	0.6	0.8	0.6
Major Depression (MDD)	0.1	0.1	2.3	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.2	1.2	-0.5	-0.8	-0.4	0.5	-0.6	1.1	0.0	-0.3	-0.1	0.6	-0.5	0.2	0.2	-0.1	0.1	-0.1
Triglycerides	0.1	0.2	1.5	0.2	1.2	-0.1	0.1	-0.2	-0.3	0.2	0.8	-0.0	-0.8	0.1	0.2	-0.4	-0.2	0.1	0.4
Heel T-Score	0.1	1.0	6.1	0.1	1.0	0.2	0.9	-0.1	-0.7	-0.7	0.2	-0.0	-2.5	1.0	-1.4	-1.9	-0.7	-0.8	0.2
Waist Hip Ratio (WHR)	0.1	0.5	3.6	-1.4	-1.9	-0.3	0.0	0.2	0.1	-0.3	0.4	0.0	0.4	0.5	-0.3	-0.5	0.3	0.9	-0.5
Systolic Blood Pressure	0.1	0.3	1.0	-0.6	-0.2	0.2	0.0	0.0	-0.6	-0.2	-0.2	0.5	-0.5	1.0	-0.7	-0.9	0.3	0.4	-0.2
Neuroticism	0.1	0.3	1.6	-0.4	-0.4	-0.1	1.3	-0.6	0.4	0.3	0.8	-0.2	0.6	-0.9	-0.1	0.3	-0.1	1.0	0.2
Hair Pigment	0.1	1.9	6.9	0.2	-1.2	-1.0	-0.6	0.8	0.3	-1.1	-1.9	-1.4	-0.3	-1.4	-2.3	-1.3	-2.3	-0.6	-2.6
Tanning	0.1	1.1	3.1	0.2	-0.7	-0.9	-1.1	-1.4	-1.4	-1.8	-0.9	-1.1	-1.4	-0.2	-0.9	-1.3	-0.5	-0.9	-0.1
Relative age of first facial hair	0.1	0.3	1.0	-0.3	-0.3	0.2	-0.2	0.0	-0.6	-0.0	-0.5	1.0	1.0	1.0	-0.5	-0.0	0.4	0.4	-0.4
Fed-up feelings	0.1	0.2	1.0	0.2	1.0	0.1	-0.3	0.1	-0.5	0.5	0.4	0.4	0.5	-0.4	-0.3	-0.1	-0.2	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.7	-0.2	0.6	0.2	0.6	-0.6	-0.4	0.1	0.5	0.3	-0.3	0.8	0.3	-0.2	0.8	0.2	0.9
Serious illness, injury or assault to yourself	0.1	0.2	0.7	-0.0	-0.6	-0.1	0.8	-0.1	0.1	-0.4	-0.3	-0.4	0.5	0.8	-0.0	0.1	0.3	-0.3	0.2
Sitting height	0.1	0.9	1.9	-0.6	-0.0	1.4	1.3	1.3	1.4	1.2	-0.1	0.9	1.1	0.3	1.0	0.7	1.1	0.4	-0.2
Nervous feelings	0.1	0.2	0.8	0.3	0.6	-0.2	0.7	-0.2	0.1	-0.1	-0.2	-0.7	-0.4	-0.9	-0.4	-0.4	-0.6	-0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.6	-0.4	0.4	0.2	-0.0	-0.5	-0.0	0.1	0.2	0.0	-0.8	0.7	0.5	-0.5	0.5	0.1	0.5
Impedance of arm (right)	0.1	0.5	1.8	0.5	0.1	-0.3	0.1	-1.3	-0.8	0.7	1.1	-0.3	0.7	-0.1	0.5	0.8	0.4	1.2	0.3
Prospective memory result	0.1	0.1	0.5	-0.0	-0.7	0.1	0.1	-0.1	-0.3	-0.7	-0.2	0.3	-0.1	0.2	0.1	-0.2	0.4	-0.3	-0.1
Impedance of arm (left)	0.1	0.3	1.6	0.8	0.1	-0.6	-0.4	-1.3	-0.9	0.1	0.5	-0.7	0.2	-0.7	-0.1	0.3	-0.2	0.5	0.1
Standing height	0.1	0.9	3.5	0.0	0.1	1.4	0.6	1.6	0.1	1.0	-1.2	0.9	0.8	0.4	0.3	-0.2	1.0	0.2	-1.9
Birth weight of first child	0.1	0.2	1.1	0.2	-1.0	-0.7	-0.1	-0.5	-0.3	-0.8	-0.5	0.1	0.5	0.3	0.1	-0.0	0.2	-0.3	-0.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.7	-0.7	-0.8	-0.2	-0.5	0.4	0.6	0.1	-0.5	0.1	0.1	0.1	-0.9	-0.7	-0.4	-0.3	-0.2
Number of full brothers	0.1	0.1	0.9	0.5	-0.1	0.1	0.3	0.6	0.0	0.2	-0.0	0.0	-0.2	-0.2	-0.5	-1.0	-0.0	-0.1	0.1
Worry too long after embarrassment	0.1	0.2	1.2	-0.4	0.0	0.4	1.1	0.2	0.3	0.3	0.7	-0.6	-0.1	-0.7	0.7	0.3	0.5	0.4	0.1
Medication for pain relief, constipation, heartburn	0.1	0.2	0.6	0.3	-0.6	-0.2	0.1	0.2	-0.7	-0.7	-0.5	-0.5	-0.0	-0.3	-0.8	-0.5	-0.5	-0.4	-0.7
Comparative height size at age 10	0.1	0.4	2.0	-0.5	0.1	0.6	-0.1	1.1	0.1	0.6	-1.0	0.5	-0.4	0.3	0.0	-0.9	0.4	-0.0	-1.4
Leg pain on walking	0.1	0.2	1.0	0.3	-0.3	-0.4	-1.0	-0.1	-0.2	-0.6	0.4	0.3	0.1	-0.2	-0.6	0.1	-0.1	-0.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.9	-0.2	-0.0	-0.1	0.2	0.4	0.6	-1.0	0.1	-0.2	-0.8	-0.3	0.4	0.2	-0.0	-0.3	0.6
Average weekly beer plus cider intake	0.1	0.1	0.5	0.3	-0.3	-0.2	0.5	-0.2	-0.5	-0.0	0.3	0.2	0.7	0.2	0.4	0.5	0.6	0.1	0.5
Supplements: Calcium	0.1	0.1	0.4	0.6	0.4	-0.4	-0.2	-0.0	0.2	0.1	0.7	-0.2	0.2	-0.6	0.2	0.6	-0.3	0.3	0.4
Impedance of whole body	0.1	0.5	2.6	0.5	-0.3	-0.8	-0.3	-1.6	-0.7	0.2	0.9	-0.8	0.3	-1.1	0.0	0.3	-0.2	1.0	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ICOSLG

Models

Trait associations