Best TWAS P=1.09e-15 · Best GWAS P=7.68e-21 conditioned to 8.83e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | GTEx | Testis | SYNGR1 | 0.39 | 0.30 | enet | 21 | 0.38 | 3.7e-18 | 5.0 | 8.0 | 1.1e-15 | -0.37 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | APOBEC3D | 0.20 | 0.01 | lasso | 3 | 0.01 | 1.5e-01 | -7.4 | -6.1 | 1.0e-09 | 0.63 | 0.03 | 0.06 | TRUE |
| 5 | NTR | Blood | SYNGR1 | 0.03 | 0.03 | enet | 6 | 0.03 | 1.0e-10 | 5.0 | 6.4 | 1.2e-10 | -0.26 | 1.00 | 0.00 | FALSE |
| 6 | YFS | Blood | SYNGR1 | 0.31 | 0.36 | bslmm | 371 | 0.38 | 3.9e-135 | 5.0 | 5.8 | 7.1e-09 | -0.08 | 1.00 | 0.00 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100506472 | 0.13 | 0.16 | bslmm | 395 | 0.16 | 1.9e-18 | 5.1 | 5.3 | 9.3e-08 | -0.12 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Spleen | SYNGR1 | 0.36 | 0.41 | lasso | 2 | 0.36 | 3.4e-10 | 5.0 | 5.3 | 9.8e-08 | -0.13 | 0.93 | 0.00 | FALSE |