TWAS hub - APOBEC3D

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1250	0.0440	7.6e-04	0.024	NA	0.034	NA	0.040	4.3e-03	NA	8.1e-04	NA	3.0e-04
2	GTEx	Artery Tibial	0.1065	0.0410	2.0e-03	0.032	NA	0.038	NA	0.023	1.5e-03	NA	5.4e-04	NA	6.1e-03
3	GTEx	Breast Mammary Tissue	0.1340	0.0520	2.3e-03	0.020	NA	0.003	NA	0.021	3.0e-02	NA	2.2e-01	NA	2.9e-02
4	GTEx	Breast Mammary Tissue (Male)	0.1998	0.1564	1.7e-01	0.015	NA	-0.013	NA	0.014	1.4e-01	NA	9.3e-01	NA	1.5e-01
5	GTEx	Breast Mammary Tissue (Female)	0.3488	0.0892	4.8e-05	-0.006	NA	0.036	NA	0.009	5.3e-01	NA	3.0e-02	NA	1.6e-01
6	GTEx	Cells Transformed fibroblasts	0.1890	0.0520	1.6e-06	0.123	NA	0.134	NA	0.155	1.7e-09	NA	3.3e-10	NA	1.1e-11
7	GTEx	Colon Transverse	0.1560	0.0650	5.3e-03	0.034	NA	0.028	NA	0.032	9.5e-03	NA	1.7e-02	NA	1.1e-02
8	GTEx	Esophagus Muscularis	0.1020	0.0460	8.5e-03	0.037	NA	0.026	NA	0.032	2.5e-03	NA	9.9e-03	NA	4.5e-03
9	GTEx	Nerve Tibial	0.1234	0.0456	1.1e-03	0.140	NA	0.090	NA	0.121	4.0e-10	NA	6.1e-07	NA	7.3e-09
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0212	0.0140	9.0e-03	0.016	0.014	0.011	NA	0.009	5.4e-03	0.0084	1.8e-02	NA	3.2e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Alzheimer’s Disease (in mother)	4.9	5.7	12.6	-3.0	-2.6	-1.2	-1.9	1.7	-2.7	-3.5	-0.8	-2.2	-2.9
Mouth/teeth dental problems: Mouth ulcers	3.8	6.0	9.7	-2.8	-2.2	-2.1	-2.9	1.1	-3.1	-2.3	-2.3	-2.8	-2.2
Had menopause	3.6	4.5	7.2	2.5	2.7	2.2	0.2	0.7	2.5	2.3	1.8	2.3	2.5
Age started oral contraceptive pill	3.6	4.4	7.8	2.4	2.8	2.0	1.1	2.2	2.3	2.1	1.8	2.2	1.8
Medication: Lisinopril	3.5	4.5	8.7	1.8	1.6	3.0	0.9	-1.4	2.9	1.6	2.8	2.9	1.1
Qualifications: O levels/GCSEs or equivalent	3.4	5.4	9.8	-3.0	-3.1	-1.4	-1.5	1.2	-2.5	-2.6	-1.4	-2.3	-3.1
Vitamin and mineral supplements	3.2	4.4	7.8	2.0	2.8	2.4	0.5	0.9	2.5	1.6	2.3	2.6	2.1
Forced vital capacity (FVC)	3.0	11.5	21.5	-4.6	-3.9	-3.1	-2.5	-0.2	-4.0	-3.5	-2.8	-3.8	-3.3
Number of children fathered	3.0	3.4	5.5	-1.9	-2.0	-1.7	0.8	0.8	-2.2	-2.4	-1.5	-2.0	-2.2
Medication: Seretide 50 evohaler	3.0	3.5	6.5	-1.4	-2.1	-2.4	0.8	-1.7	-2.1	-0.6	-2.6	-2.4	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	4.8	2.0	2.0	2.0	0.1	-0.3	2.2	2.0	1.8	2.0	1.8
Crohns Disease (2017)	2.3	5.0	37.3	-0.9	-0.5	-0.5	-6.1	2.7	-1.0	-1.4	-0.3	-0.7	-0.8
Pain all over the body in last month	2.3	2.4	4.2	-1.8	-1.5	-1.0	-1.6	-1.8	-1.5	-2.0	-0.6	-1.3	-1.8
Fluid intelligence score	2.3	4.9	9.4	-2.3	-2.6	-0.7	-2.7	3.1	-2.1	-2.2	-0.8	-1.8	-2.4
Forced expiratory volume in 1-second (FEV1)	2.3	7.9	14.9	-3.9	-3.4	-2.4	-2.2	1.2	-3.2	-3.1	-2.1	-3.0	-2.7
Irritable Bowel Disease (IBD)	2.2	5.3	44.9	0.2	0.2	0.1	-6.7	2.8	0.1	-0.3	0.1	-0.0	0.4
Ever highly irritable/argumentative for 2 days	2.2	2.7	4.0	2.0	1.5	1.5	1.7	0.5	1.9	1.8	1.4	1.7	1.7
Arm predicted mass (right)	2.2	11.2	18.2	-4.2	-4.3	-3.4	-3.4	-0.9	-3.5	-3.0	-3.4	-3.9	-2.0
Eye problems/disorders: Cataract	2.2	2.5	4.4	-2.0	-1.8	-1.4	-0.7	-1.4	-1.6	-2.1	-1.2	-1.7	-1.4
High cholesterol (Self-reported)	2.2	3.8	7.4	2.4	2.7	1.7	1.0	0.1	2.1	2.3	1.3	1.9	2.4
Number of full brothers	2.1	2.6	3.8	-2.0	-1.7	-1.8	-1.7	-1.5	-1.6	-0.9	-1.9	-1.8	-0.8
Schizophrenia vs Biploar Disorder	2.0	2.6	7.1	-2.1	-2.2	-2.7	-0.5	-0.5	-1.9	-0.7	-2.3	0.0	0.0
Alzheimer’s Disease (including proxy)	2.0	2.9	5.0	-1.8	-1.8	-2.0	-0.1	-0.2	-2.2	-1.7	-1.7	-2.2	-1.6
Crohns Disease (2012)	2.0	3.1	17.0	-0.5	-0.2	-0.4	-4.1	3.5	-0.6	-0.9	-0.3	-0.5	0.0
Financial difficulties in last 2 years	2.0	2.7	11.3	1.4	1.2	0.6	3.4	-2.1	1.2	1.8	0.2	1.0	1.2
Commuting to job workplace: Walk	2.0	2.1	5.3	-1.2	-1.2	-1.9	-0.1	-0.7	-1.8	-0.7	-2.3	-2.1	-0.9
Arm predicted mass (left)	2.0	10.4	18.3	-4.3	-4.1	-3.1	-3.3	-0.1	-3.3	-3.2	-3.1	-3.7	-2.0
Arm fat-free mass (right)	1.9	9.9	16.9	-4.0	-4.1	-3.2	-3.1	-0.7	-3.3	-2.9	-3.2	-3.7	-1.8
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.2	1.9	2.0	1.0	0.6	1.0	1.4	2.0	0.7	1.2	1.8
Blood White Count	1.8	13.1	26.0	4.2	5.1	2.3	2.4	3.1	3.8	4.1	2.6	3.6	3.9
Ever used hormone-replacement therapy (HRT)	1.8	2.3	3.5	1.3	1.6	1.6	-1.4	-1.3	1.9	1.5	1.3	1.8	1.6
Trunk fat-free mass	1.8	10.3	18.6	-4.3	-4.1	-2.8	-3.2	-0.2	-3.4	-3.4	-2.9	-3.6	-2.1
Trunk predicted mass	1.8	10.3	18.7	-4.3	-4.1	-2.8	-3.3	-0.2	-3.4	-3.4	-2.9	-3.6	-2.1
Health satisfaction	1.8	2.4	3.8	-1.6	-1.3	-1.8	-0.6	-1.5	-1.8	-1.0	-1.9	-2.0	-1.3
Whole body water mass	1.8	10.2	17.0	-4.1	-4.1	-3.2	-3.2	-0.5	-3.4	-3.0	-3.2	-3.7	-1.9
Arm fat-free mass (left)	1.8	9.4	16.2	-4.0	-4.0	-2.9	-3.1	-0.3	-3.2	-3.0	-3.0	-3.4	-1.9
Alzheimer’s Disease (in father)	1.7	1.8	10.6	0.7	0.4	-0.8	3.2	-2.2	-0.1	0.9	-0.8	-0.3	0.3
Respiratory disease	1.7	3.8	8.5	-0.9	-1.5	-2.7	1.7	-2.5	-1.9	-0.3	-2.9	-2.4	-0.8
Multivitamins +/- minerals	1.7	2.2	5.1	-1.1	-2.3	-1.7	0.1	-1.2	-1.7	-0.9	-1.7	-1.8	-1.3
Pulse wave peak to peak time	1.7	2.0	7.3	-1.9	-2.1	-0.1	-0.8	-0.0	-1.1	-2.7	0.4	-0.7	-1.7
Whole body fat-free mass	1.7	9.8	16.2	-4.0	-4.0	-3.1	-3.2	-0.5	-3.3	-2.9	-3.2	-3.6	-1.8
Breast cancer (self-reported)	1.7	2.1	4.7	1.8	1.5	1.3	0.1	-2.2	1.4	1.4	1.1	1.5	1.2
Lupus	1.6	2.5	5.2	-2.2	-1.8	-1.2	-0.7	-0.6	-1.6	-2.2	-0.6	-1.2	-2.3
Alcohol usually taken with meals	1.6	2.6	4.6	-1.5	-1.4	-2.0	-2.0	-0.2	-1.7	-0.8	-2.1	-1.9	-1.2
Pulse wave reflection index	1.6	1.9	4.2	1.8	1.4	-0.4	2.0	-1.6	0.6	2.1	-0.8	0.3	1.5
Mood swings	1.6	2.8	4.9	1.6	2.0	1.5	0.1	-1.1	2.1	2.2	1.2	1.8	2.1
Osteoarthritis (self-reported)	1.6	2.0	4.6	-1.0	-1.2	-2.1	0.3	-1.2	-1.6	-0.6	-2.1	-1.8	-0.9
Basal metabolic rate	1.6	8.8	14.6	-3.8	-3.8	-3.0	-3.0	-0.8	-3.0	-2.6	-3.1	-3.4	-1.6
Primary Biliary Cirrhosis	1.5	2.2	4.3	2.0	1.7	-0.1	0.3	-1.8	1.4	2.1	-0.3	1.0	2.0
Type 2 Diabetes (T2D) (2012)	1.5	1.7	3.3	-1.3	-1.8	-1.8	-0.5	-1.1	-1.4	-0.4	-1.7	-1.6	-0.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.7	3.1	0.8	1.7	1.6	0.2	-0.4	1.7	1.0	1.5	1.7	1.5
Time employed in main current job	1.5	1.7	3.5	1.5	1.9	1.2	1.0	-0.1	1.5	1.2	1.3	1.6	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	4.5	1.8	1.5	1.2	1.5	0.5	1.8	2.1	0.8	1.3	1.9
Leg fat-free mass (right)	1.5	7.8	12.2	-3.4	-3.5	-3.1	-2.9	-0.8	-2.9	-2.0	-3.3	-3.3	-1.2
Leg predicted mass (right)	1.5	8.2	12.8	-3.5	-3.6	-3.1	-3.0	-0.7	-3.0	-2.1	-3.3	-3.4	-1.4
Leg predicted mass (left)	1.4	7.2	11.3	-3.2	-3.4	-3.0	-2.8	-1.1	-2.7	-1.9	-3.2	-3.2	-1.1
Birth weight	1.4	2.9	5.9	-2.0	-2.4	-2.1	-1.3	-0.4	-1.7	-1.3	-1.9	-2.0	-1.2
Forced vital capacity (FVC), Best measure	1.4	5.3	9.9	-3.1	-2.5	-2.2	-1.7	-0.4	-2.8	-2.3	-2.0	-2.7	-2.1
Illnesses of siblings: Diabetes	1.4	1.8	3.0	1.3	1.3	1.6	-0.0	1.0	1.7	1.0	1.5	1.6	1.4
Bipolar Disorder (2018)	1.3	2.1	5.5	2.4	1.4	0.2	1.6	-1.4	1.3	1.8	0.0	1.0	1.8
Rheumatoid Arthritis	1.3	1.8	3.6	1.5	1.4	1.0	0.9	-1.9	1.5	1.3	0.8	1.3	1.6
Illnesses of father: Heart disease	1.3	1.8	4.7	0.6	0.6	2.1	-0.4	2.2	1.3	0.1	1.9	1.6	0.4
Loneliness, isolation	1.3	1.9	5.1	1.0	1.2	1.2	1.2	-2.2	1.3	1.6	1.0	1.3	1.1
Mother’s age at death	1.3	1.6	3.3	0.8	0.8	1.8	0.0	0.1	1.7	1.0	1.8	1.8	0.8
Commuting to job workplace: Cycle	1.3	1.6	7.5	-0.6	-0.3	-0.6	-2.7	2.5	-0.6	-0.3	-0.7	-0.7	-0.5
Ulcerative Colitis (UC)	1.2	2.3	16.2	1.0	0.7	0.3	-4.0	1.6	0.7	0.8	-0.0	0.3	1.3
Leg fat-free mass (left)	1.2	6.6	10.3	-3.0	-3.2	-2.9	-2.7	-1.0	-2.6	-1.7	-3.1	-3.1	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	7.3	-2.7	-2.3	-1.8	-1.4	0.5	-2.3	-2.1	-1.6	-2.2	-1.8
Pulse wave Arterial Stiffness index	1.2	1.3	5.5	1.4	1.7	-0.1	0.4	0.0	0.7	2.4	-0.6	0.4	1.4
Mean time to correctly identify matches	1.2	2.4	4.9	2.2	1.8	0.9	1.2	-0.8	1.8	1.7	1.0	1.5	1.9
Pulse rate, automated reading	1.2	3.9	7.3	-2.7	-2.3	-0.9	-1.3	2.1	-2.2	-2.7	-0.6	-1.6	-2.2
Supplements: Vitamin C	1.2	1.5	2.8	-1.1	-1.5	-1.7	-0.5	-1.2	-1.3	-0.6	-1.6	-1.5	-0.5
Average weekly red wine intake	1.2	1.7	6.6	0.1	0.6	-2.0	-1.3	-0.2	-0.8	0.8	-2.6	-1.5	1.0
Reaction Time	1.1	2.0	4.0	2.0	1.6	0.7	0.7	-0.6	1.7	1.6	0.8	1.4	2.0
Breast Cancer	1.1	2.7	8.5	0.7	1.1	2.5	1.1	1.2	1.7	0.1	2.9	2.2	0.3
Eye problems/disorders: Diabetes related eye disease	1.1	1.3	3.9	-1.2	-1.2	-1.1	-0.1	-2.0	-1.0	-0.6	-1.0	-1.1	-1.1
Serious illness, injury or assault to yourself	1.1	1.4	4.1	-1.8	-1.6	-0.1	-0.5	-0.5	-0.6	-2.0	0.6	-0.3	-1.6
Hayfever, allergic rhinitis or eczema	1.1	2.3	5.9	-0.8	-1.2	-1.7	2.4	-1.1	-1.5	-0.4	-1.8	-1.6	-1.7
Sitting height	1.1	7.9	16.5	-4.1	-3.5	-1.9	-2.6	0.2	-3.0	-3.3	-2.0	-3.0	-2.5
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	3.2	1.7	1.1	0.3	1.7	0.0	1.3	1.8	0.0	0.9	1.5
Medication: Simvastatin	1.1	1.6	3.4	0.9	1.4	1.7	1.0	-0.1	1.4	0.5	1.8	1.6	1.1
Mouth/teeth dental problems: Dentures	1.1	1.9	3.2	1.4	1.4	1.6	0.1	1.2	1.6	1.0	1.7	1.8	1.1
Prospective memory result	1.1	1.4	3.4	1.4	1.5	0.8	1.9	0.2	1.2	0.9	0.9	1.3	0.8
Standing height	1.1	10.5	23.2	-4.8	-4.1	-2.4	-3.8	-1.5	-3.1	-3.2	-2.5	-3.4	-2.0
Peak expiratory flow (PEF)	1.1	2.6	6.3	-1.7	-1.8	-1.6	-0.9	2.5	-1.7	-1.4	-1.4	-1.7	-1.0
Eye problems/disorders: None of the above	1.1	1.3	2.2	1.2	0.9	1.5	1.3	0.5	1.2	0.7	1.4	1.4	0.7
Emphysema/chronic bronchitis	1.1	1.2	4.5	-0.8	-0.7	-1.0	0.8	-2.1	-1.1	-0.9	-1.0	-1.1	-0.7
Hearing aid user	1.1	1.2	2.0	0.5	1.4	1.4	-1.1	1.1	1.1	0.3	1.4	1.2	0.6
Pain type(s) experienced in last month: Hip pain	1.1	1.4	4.8	0.5	0.3	-1.7	-0.4	-1.1	-0.4	1.4	-2.2	-1.1	1.0
Ever smoked	1.1	2.0	5.2	-0.9	-1.3	-2.1	-0.7	-0.3	-1.7	-0.3	-2.3	-1.9	-0.7
Medication: Blood pressure	1.0	1.8	3.6	1.1	0.7	1.9	-0.0	0.3	1.9	1.0	1.9	1.9	1.0
Angina (self-reported)	1.0	1.3	2.4	1.4	1.1	1.5	0.1	-0.6	1.3	1.0	1.4	1.6	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.0	-0.9	-1.2	-1.2	-1.2	0.6	-1.3	-0.7	-1.3	-1.4	-0.9
Age at last live birth	1.0	1.5	2.9	0.9	1.3	1.5	-0.3	0.5	1.5	1.2	1.2	1.4	1.7
Myopia	1.0	1.5	4.6	-1.5	-1.2	0.2	-0.1	1.4	-0.9	-2.1	0.5	-0.5	-1.8
Cholesterol lowering medication	1.0	1.5	5.2	0.9	1.1	1.1	0.6	-2.3	1.0	0.9	0.9	1.1	1.6
Verbal and Numeric Reasoning (VNR)	0.9	2.2	6.8	-1.3	-1.5	0.6	-1.8	2.6	-1.1	-1.7	0.3	-0.7	-1.6
Body Mass Index (BMI) (2010)	0.9	1.2	3.3	-1.2	-1.8	-1.1	-0.0	-1.1	-1.1	-1.1	-0.8	-0.9	-1.1
HbA1C	0.9	1.0	4.1	0.6	0.2	0.1	0.7	-1.3	0.7	2.0	0.9	0.6	1.2
Ulcerative Colitis	0.9	1.4	11.0	0.2	-0.2	-0.6	-3.3	0.8	-0.3	0.3	-0.9	0.0	0.8
Hand grip strength (left)	0.9	2.3	14.1	-1.1	-0.7	-1.1	-1.1	3.8	-1.0	-0.3	-1.3	-1.2	-0.4
Angina	0.9	1.2	2.2	1.2	1.0	1.4	0.2	-0.4	1.2	0.9	1.4	1.5	0.7
Medication: Co-codamol	0.9	1.0	2.2	-0.6	-0.7	-1.3	-1.1	-1.4	-0.9	0.2	-1.5	-1.1	0.1
Age when periods started (menarche)	0.9	2.2	3.1	-1.5	-1.6	-1.8	-1.5	-1.4	-1.4	-1.1	-1.6	-1.6	-1.2
Had other major operations	0.9	1.2	8.5	0.3	0.0	-0.3	1.2	-2.9	0.3	1.0	-0.4	0.2	0.5
Qualifications: None of the above	0.9	2.0	3.7	1.7	1.5	0.3	1.9	-1.9	1.2	1.6	0.2	0.9	1.7
Hip circumference	0.9	4.0	6.9	-2.3	-2.6	-2.3	-0.9	-1.6	-2.0	-1.6	-2.5	-2.4	-0.9
Lung cancer (father)	0.9	1.1	3.0	1.1	0.6	1.7	0.7	0.8	0.9	0.4	1.6	1.2	0.6
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	3.8	-1.0	-0.8	-1.8	-0.5	-0.8	-1.5	-0.4	-1.9	-1.6	-0.5
Wheeze or whistling in the chest in last year	0.9	1.7	6.1	-1.1	-1.8	-0.9	0.6	-2.5	-1.0	-0.9	-0.8	-1.1	-1.1
Medication: Omeprazole	0.9	1.0	4.6	0.5	0.4	-0.2	-1.5	-2.2	0.2	0.9	-0.7	-0.2	1.3
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.9	-0.5	-0.4	-0.9	-1.8	-2.0	-0.7	0.0	-1.1	-0.9	0.1
Prostate Cancer	0.8	1.2	8.6	-0.6	-0.6	-0.1	-1.2	-2.9	-0.4	-0.6	-0.2	-0.5	-0.6
Height	0.8	14.9	27.5	-5.2	-4.0	-3.6	-4.5	-2.7	-4.0	-3.2	-4.0	-4.5	-1.9
Waist Hip Ratio (WHR)	0.8	3.6	6.9	2.1	2.2	0.6	1.0	-2.1	2.0	2.6	0.6	1.5	2.6
Allergy or Eczema	0.8	2.2	8.5	-0.3	-1.0	-1.6	2.9	-1.5	-1.2	-0.0	-1.8	-1.5	-1.1
Average weekly spirits intake	0.8	1.0	1.9	1.2	1.3	0.3	0.7	1.4	0.9	1.3	0.1	0.7	1.3
Fed-up feelings	0.8	1.5	3.3	0.6	1.0	1.3	0.7	-1.8	1.3	1.3	1.1	1.3	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.8	0.3	1.3	1.1	0.3	-0.4	1.3	1.3	1.1	1.2	1.3
Medication: Atenolol	0.8	1.0	2.4	1.4	1.4	0.5	1.5	-0.4	0.9	0.7	0.7	0.9	0.8
Allergy	0.8	1.7	4.2	0.5	1.0	1.5	-2.0	1.6	1.2	-0.1	1.7	1.4	1.1
Weight	0.8	3.7	6.1	-2.4	-2.5	-2.2	-1.8	-1.5	-1.6	-1.2	-2.4	-2.1	-0.3
Worrier / anxious feelings	0.8	1.5	3.0	1.2	1.4	1.2	1.7	-0.8	1.3	1.4	0.9	1.1	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.7	-1.1	-1.0	-0.8	-0.2	-0.8	-0.9	-1.3	-0.6	-1.0	-1.0
Asthma	0.8	1.6	4.3	-0.5	-1.2	-1.7	0.5	-1.7	-1.0	0.3	-2.1	-1.6	-0.1
Medication: Cholesterol lowering	0.8	1.3	3.0	0.7	0.9	1.6	0.0	1.2	1.4	0.6	1.7	1.5	0.5
Impedance of arm (left)	0.8	3.9	5.7	2.2	2.4	1.9	1.1	-1.4	2.3	2.2	1.9	2.4	1.6
Length of working week for main job	0.8	0.9	5.5	0.0	0.1	-0.1	-2.4	-1.7	0.1	0.3	-0.2	0.0	0.1
Medication: Amlodipine	0.8	1.1	3.0	1.1	0.9	1.0	0.3	1.7	1.1	1.1	0.9	1.1	0.9
Heart disease (mother)	0.8	1.0	2.9	1.4	1.7	-0.1	-0.2	-0.6	0.8	1.4	-0.4	0.3	1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.8	3.8	-1.9	-1.9	-0.9	-1.5	-0.9	-1.2	-1.4	-0.8	-1.3	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	6.7	-0.1	-0.6	-0.4	-1.1	-2.6	-0.2	0.1	-0.4	-0.2	0.0
Medication for cholesterol	0.8	1.2	5.6	-0.7	-0.9	-0.8	-0.8	2.4	-0.9	-0.8	-0.8	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	3.4	-1.8	-1.5	-0.6	-0.5	1.6	-1.1	-1.7	-0.1	-0.8	-1.7
Unable to work because of sickness or disability	0.8	1.0	2.7	-1.4	-1.6	-0.1	-0.1	-0.7	-0.7	-1.5	-0.0	-0.7	-1.3
Basal cell carcinoma (self-reported)	0.8	1.0	7.8	-0.8	-0.6	0.6	-2.8	-0.8	0.2	-0.2	0.4	0.2	0.0
Frequency of depressed mood in last 2 weeks	0.7	1.0	1.7	0.1	0.7	1.3	0.7	-0.9	1.3	0.7	1.3	1.2	1.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.7	1.0	0.9	1.0	0.1	-0.9	1.3	0.9	0.8	1.1	1.0
Ever had hysterectomy (womb removed)	0.7	0.8	1.7	1.2	0.6	-0.6	-1.0	-0.7	0.2	1.3	-1.1	-0.2	1.0
Hand grip strength (right)	0.7	1.9	11.2	-1.3	-0.8	-0.8	-1.3	3.3	-0.9	-0.5	-0.8	-1.0	-0.6
Qualifications: CSEs or equivalent	0.7	0.9	1.9	-1.2	-1.4	-0.8	-0.9	-0.7	-0.7	-1.1	-0.3	-0.6	-1.3
Impedance of arm (right)	0.7	3.4	5.8	2.0	2.4	1.8	1.5	-0.7	2.1	1.8	2.0	2.3	1.2
Illnesses of mother	0.7	0.9	1.8	0.4	0.5	1.2	-1.3	0.4	1.3	0.9	0.9	1.2	0.8
Breastfed as a baby	0.7	0.9	3.2	-0.1	-0.2	-1.6	-0.2	-0.4	-0.9	0.4	-1.8	-1.3	0.1
Glaucoma (self-reported)	0.7	0.8	2.5	-0.5	-0.5	-1.2	0.1	-0.7	-0.9	0.5	-1.6	-1.1	-0.8
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.4	-0.1	-0.1	-1.4	0.9	0.0	-0.9	0.4	-1.8	-1.3	-0.2
Number of full sisters	0.7	0.9	2.7	-0.4	-0.6	-1.3	0.6	-0.8	-1.2	0.1	-1.6	-1.3	-0.2
Family relationship satisfaction	0.7	0.8	5.5	0.0	0.2	-0.0	-2.3	-1.6	-0.0	0.4	-0.2	-0.0	-0.0
Friendships satisfaction	0.7	0.9	2.0	0.2	0.7	1.4	-1.0	-0.7	0.9	0.5	1.4	1.1	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.1	-0.4	-0.2	-1.1	1.7	0.8	-1.0	-0.2	-1.0	-0.8	-0.9
Asthma (self-reported)	0.7	1.5	3.9	-0.5	-1.2	-1.6	0.6	-1.6	-0.9	0.3	-2.0	-1.5	-0.1
Ever taken oral contraceptive pill	0.7	0.8	1.6	1.0	1.3	0.8	0.3	-1.2	1.0	1.0	0.6	0.9	0.6
Medication: Atorvastatin	0.7	0.8	1.3	1.1	0.4	1.0	1.0	-0.4	1.1	1.1	0.8	1.0	0.6
Alcohol drinker status: Never	0.7	0.8	3.9	0.4	0.3	1.2	2.0	-0.7	0.7	-0.2	1.1	0.8	0.1
Depressed Affect (Nagel 2018)	0.6	1.4	7.6	0.6	0.7	0.5	0.4	-2.8	1.0	1.3	0.3	0.8	1.2
Triglycerides	0.6	0.9	3.0	-0.7	-1.0	-0.7	-0.3	-0.9	-1.0	-1.2	-0.4	-0.8	-1.7
Severe depression (siblings)	0.6	0.7	1.9	-0.0	-0.5	-1.1	-0.4	-1.4	-0.7	0.0	-1.3	-1.1	-0.2
Average weekly fortified wine intake	0.6	0.7	1.5	1.1	1.2	0.9	0.4	0.1	0.7	0.8	0.6	0.8	1.0
Nervous feelings	0.6	1.1	3.8	-0.0	0.5	1.7	1.1	-0.7	0.8	-0.8	2.0	1.1	-0.6
Neuroticism score	0.6	1.3	2.6	1.0	1.2	1.6	0.8	0.3	1.2	1.4	1.2	1.2	1.0
Hair/balding pattern: Pattern 3	0.6	0.9	2.1	1.3	1.4	0.8	0.4	-0.5	1.0	0.9	0.6	0.9	1.1
Qualifications: A levels/AS levels or equivalent	0.6	1.4	3.4	-1.0	-1.4	0.1	-1.9	1.5	-0.9	-0.7	-0.1	-0.7	-1.7
Had major operations	0.6	0.6	3.0	0.6	0.6	0.7	1.7	0.6	0.6	0.6	0.6	0.6	0.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	4.4	-0.1	0.2	0.3	-1.5	2.1	-0.1	-0.2	0.2	-0.1	-0.0
Knee pain experienced in last month	0.6	1.0	1.7	-1.0	-0.8	-1.3	-1.0	-1.0	-0.9	-0.6	-1.2	-1.2	-0.3
Guilty feelings	0.6	0.9	6.9	-0.5	-0.2	1.0	0.1	2.6	-0.1	0.1	0.7	0.0	-0.2
Eye problems/disorders: Glaucoma	0.6	0.7	2.3	0.9	0.9	0.0	1.5	0.9	0.4	1.2	-0.3	0.3	0.4
Medication: Paracetamol	0.6	0.9	2.9	-0.5	-1.1	-1.0	-1.7	-1.2	-0.5	0.1	-1.0	-0.8	-0.4
Bipolar Disorder (2011)	0.5	0.5	2.7	1.1	0.7	0.3	1.6	0.1	0.0	0.0	0.5	0.0	0.0
Coronary Artery Disease (CAD)	0.5	0.6	4.3	0.2	0.4	0.4	2.1	0.3	0.2	-0.3	0.9	0.0	0.0
Blood Red Count	0.5	5.1	18.7	1.2	2.5	2.5	-1.4	4.3	1.8	1.3	2.4	1.9	1.5
Number of treatments/medications taken	0.5	0.9	1.9	1.0	0.1	1.2	0.1	-0.6	1.3	0.6	1.4	1.4	0.1
Medication for hormone replacement therapy	0.5	0.5	3.0	0.1	0.4	0.7	0.4	-1.7	0.7	0.0	0.8	0.7	-0.0
Medication: Metformin	0.5	0.7	1.5	0.9	1.1	0.9	1.2	-0.8	0.7	0.5	0.7	0.7	0.2
Diabetes (father)	0.5	0.7	2.3	1.1	0.5	-0.4	0.5	-1.5	0.4	1.2	-0.7	0.1	0.7
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	3.9	0.3	0.3	-0.0	-2.0	1.0	-0.3	-0.1	-0.3	-0.2	0.1
Alcohol intake versus 10 years previously	0.5	0.8	1.8	0.1	-0.5	-1.2	-0.6	-1.3	-0.7	0.9	-1.4	-1.0	-0.1
Father’s age at death	0.5	0.6	2.4	0.1	0.6	0.8	-1.6	0.5	0.9	0.4	0.7	0.7	0.9
Exposure to tobacco smoke at home	0.5	0.6	2.1	-0.5	-0.9	0.2	-1.4	-0.8	-0.3	-0.8	0.2	-0.1	-0.9
Loud music exposure frequency	0.5	0.5	2.8	0.1	-0.8	0.1	0.0	1.7	-0.4	-0.7	0.1	-0.2	-0.9
Migraine (self-reported)	0.5	0.6	2.1	-0.9	-1.3	0.2	-1.5	0.1	-0.3	-0.9	0.3	-0.2	-0.5
Medication: Allopurinol	0.5	0.7	1.7	-1.3	-0.5	-0.2	-1.3	0.9	-0.6	-1.1	0.1	-0.4	-1.0
Overall health rating	0.5	1.0	9.3	-0.2	-0.8	0.0	0.3	-3.1	0.3	0.1	0.1	0.2	0.3
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.3	0.9	0.3	0.4	-0.3	-0.5	1.0	0.6	0.7	1.0	1.1
Smoking status: Previous	0.5	0.7	2.0	0.4	0.7	-1.0	0.4	1.2	-0.2	0.9	-1.4	-0.6	0.5
Qualifications: nursing, teaching	0.5	0.7	2.4	0.1	-0.1	1.4	-0.0	0.2	1.1	0.0	1.5	1.3	0.1
Osteoporosis (self-reported)	0.5	0.6	1.3	1.1	0.5	0.7	0.5	-1.2	0.9	0.6	0.8	0.9	0.4
Miserableness	0.5	0.8	2.6	0.6	0.8	0.5	-0.4	-0.5	1.0	1.5	0.1	0.6	1.6
Wears glasses or contact lenses	0.5	0.5	1.3	0.2	0.4	0.9	-0.3	1.1	0.9	0.6	0.7	0.7	0.9
Irritability	0.5	0.8	3.9	0.4	0.8	0.2	-2.0	0.3	0.5	1.1	-0.2	0.3	1.2
Risk taking	0.5	0.8	3.6	0.3	0.2	-1.2	-0.8	-1.9	-0.3	0.3	-1.1	-0.5	0.4
Impedance of whole body	0.5	2.3	3.9	1.6	1.8	1.7	1.0	-0.7	1.8	1.4	1.8	2.0	0.8
Bipolar Disorder or Schizophrenia	0.4	0.9	2.4	1.2	0.5	-0.5	0.6	-1.5	0.9	1.3	-0.4	0.5	1.2
Depression (Nagel 2018)	0.4	0.5	1.3	-0.2	0.7	0.7	0.8	-1.1	0.7	0.5	0.9	0.8	0.5
LDL Cholesterol	0.4	0.6	2.1	-1.0	-1.1	0.1	-0.0	0.7	-0.5	-1.0	0.2	-0.3	-1.4
Blood Platelet Count	0.4	4.4	7.2	-1.6	-1.7	-2.5	2.1	0.7	-2.7	-2.4	-1.8	-2.3	-2.4
Lung FEV1/FVC ratio	0.4	2.2	5.6	1.7	2.2	0.3	-0.4	2.4	1.2	1.2	0.3	1.0	2.1
Diabetes (mother)	0.4	0.5	3.2	0.6	0.1	0.4	1.8	-0.8	0.5	0.4	0.4	0.5	0.4
Pack years adult smoking proportion	0.4	0.6	2.0	0.1	-0.2	1.0	0.3	-0.7	0.0	-1.4	1.4	0.6	-0.6
Impedance of leg (right)	0.4	1.8	4.7	1.1	1.2	1.9	0.9	-0.4	1.5	0.4	2.2	1.8	0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.2	-0.8	-0.7	0.6	0.4	0.5	0.2	-0.7	1.1	0.4	-0.7
Number of incorrect matches in round	0.4	0.7	6.1	-0.1	-0.2	-0.4	0.5	-2.5	-0.2	0.0	-0.4	-0.2	-0.1
Past tobacco smoking	0.4	0.6	2.8	-0.0	0.1	1.3	-0.0	-0.3	0.7	-0.6	1.7	1.0	-0.2
Heart attack	0.4	0.5	1.1	-1.0	-0.6	-0.5	-0.7	-0.7	-0.7	-0.8	-0.2	-0.5	-0.9
Medication: Ramipril	0.4	0.6	1.5	0.3	0.6	0.9	0.5	1.2	0.5	-0.1	1.2	0.9	0.1
Pulse rate	0.4	0.6	3.0	-0.1	-0.2	0.8	0.8	1.7	0.1	-0.6	1.1	0.5	-0.3
Noisy workplace	0.4	0.5	1.6	0.4	0.1	-0.9	0.2	-1.3	-0.0	1.0	-1.0	-0.3	0.4
Medication: Lansoprazole	0.4	0.4	0.8	0.6	0.8	0.2	-0.4	-0.8	0.8	0.9	0.2	0.7	0.5
Gout (self-reported)	0.4	0.6	2.9	-0.8	-0.3	-0.4	-0.9	1.7	-0.5	-0.2	-0.4	-0.5	-0.4
Age at first live birth	0.4	0.8	2.1	0.1	0.4	1.2	0.0	1.4	1.0	0.2	1.3	1.0	0.5
Qualifications: College or University degree	0.4	1.3	10.1	-0.7	-0.6	0.2	-3.2	1.3	-0.5	-0.3	-0.2	-0.4	-0.1
Suffer from ‘nerves’	0.4	0.6	2.1	0.2	0.2	1.4	0.2	0.8	0.7	-0.0	1.5	0.8	-0.1
Handedness (chirality/laterality): Left-handed	0.4	0.4	2.0	0.4	0.2	-0.2	1.4	1.4	0.1	-0.1	-0.3	-0.2	-0.1
Long-standing illness, disability or infirmity	0.4	0.6	3.1	-0.7	-1.0	-0.4	-0.7	-1.8	-0.4	-0.1	-0.4	-0.4	-0.3
Mineral and other dietary supplements	0.4	0.5	1.2	0.8	1.0	0.7	0.4	0.6	0.8	0.5	0.6	0.7	1.1
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.0	-0.5	-0.1	-0.6	0.4	-0.0	-1.0	-0.9	-0.6	-0.9	-0.7
Medication: Blood pressure	0.4	0.7	1.4	0.7	1.0	1.0	0.1	-0.9	0.8	0.2	1.2	1.1	0.4
Diastolic blood pressure, automated reading	0.4	1.3	8.8	-0.1	0.2	1.0	-0.7	3.0	0.7	0.1	1.0	0.8	0.0
Pack years of smoking	0.4	0.5	1.8	0.6	0.3	1.0	0.8	-0.2	0.2	-0.9	1.4	0.7	-0.2
Intelligence (Savage-Jansen 2018)	0.3	0.9	5.0	-0.8	-0.7	0.4	-0.9	2.2	-0.7	-0.7	0.0	-0.7	-0.6
Major Depression (MDD)	0.3	0.4	1.5	-1.2	-1.1	0.0	-0.2	-0.3	-1.0	-0.3	0.0	0.0	0.0
Fasting Glucose	0.3	0.3	1.4	-0.1	-0.6	-0.1	1.2	-1.1	-0.0	0.0	0.5	0.1	-0.4
Smoking Status	0.3	0.6	1.9	-0.3	-0.3	-1.1	-0.3	-0.9	-0.8	-0.2	-1.4	-1.1	0.1
Systolic blood pressure, automated reading	0.3	1.0	3.1	0.4	1.1	1.1	-0.2	1.8	1.0	-0.1	1.3	1.0	0.6
Supplements: Zinc	0.3	0.3	0.8	-0.3	-0.5	-0.7	0.6	-0.9	-0.5	-0.2	-0.7	-0.6	-0.5
Townsend deprivation index at recruitment	0.3	0.4	1.5	0.2	1.0	-0.0	-0.4	-1.2	0.3	0.7	-0.2	0.0	0.8
Relative age voice broke	0.3	0.4	3.0	0.1	-0.1	-0.3	1.7	0.4	-0.6	-0.2	-0.4	-0.5	-0.3
Taking other prescription medications	0.3	0.4	1.7	0.2	-0.5	-0.7	0.7	-1.3	-0.0	0.5	-0.8	-0.3	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	2.4	0.9	1.5	0.6	0.2	0.7	0.9	0.9	0.6	0.8	1.0
High blood pressure	0.3	0.8	1.8	1.0	0.8	0.4	-0.3	-1.3	1.0	1.3	0.2	0.8	1.0
Chronic bronchitis/emphysema (father)	0.3	0.4	1.3	-0.3	-0.5	-0.7	0.4	-1.2	-0.6	0.3	-0.7	-0.6	-0.5
High blood pressure (mother)	0.3	0.4	1.4	0.8	0.7	0.1	0.5	-1.2	0.4	0.5	0.2	0.3	0.7
Impedance of leg (left)	0.3	1.3	4.0	0.8	1.0	1.7	0.9	-0.0	1.2	0.2	2.0	1.6	-0.0
Waist circumference	0.3	1.2	5.8	-0.3	-0.5	-1.3	0.4	-2.4	-0.1	0.6	-1.5	-0.7	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.8	-0.3	-0.1	0.5	0.7	-1.7	0.2	0.3	0.3	0.3	-0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.0	-0.7	-0.9	0.0	-1.0	-0.7	-0.2	-0.3	0.1	-0.1	-0.7
Depression (self-reported)	0.3	0.4	2.0	0.9	-0.0	-0.1	0.0	-0.4	0.6	1.4	-0.2	0.3	0.5
Hair/balding pattern: Pattern 4	0.3	0.7	4.0	-0.8	-0.8	-0.5	-0.6	-2.0	-0.5	-0.2	-0.5	-0.4	-0.1
Blood clot in the leg (DVT)	0.3	0.3	0.7	-0.9	-0.8	-0.4	-0.6	0.1	-0.6	-0.5	-0.2	-0.5	-0.8
Medication: Paracetamol	0.3	0.5	1.3	-0.0	-0.4	-1.1	-0.8	-1.0	-0.1	0.7	-1.2	-0.6	0.2
Headache pain in last month	0.3	0.4	0.9	0.5	-0.1	0.8	0.6	-0.0	0.9	0.8	0.8	0.9	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	2.1	-1.1	-0.9	-0.2	0.5	-0.5	-0.3	-1.5	0.3	-0.2	-1.3
Comparative body size at age 10	0.3	0.8	2.0	-0.1	-0.2	1.4	-0.9	1.2	0.7	-0.3	1.4	1.0	0.3
Neck or shoulder pain in last month	0.3	0.4	1.2	-0.8	-1.1	-0.0	0.0	0.5	-0.5	-0.4	0.2	-0.1	-1.1
Alcohol intake frequency.	0.3	0.7	3.1	0.8	-0.4	-0.2	1.6	-1.8	-0.0	0.6	-0.3	-0.2	0.7
Comparative height size at age 10	0.3	1.6	5.3	-1.9	-1.5	0.2	-2.3	-0.8	-0.5	-1.7	0.2	-0.4	-0.8
Arm fat percentage (left)	0.3	1.0	2.5	0.9	0.6	-0.3	0.8	-1.6	1.0	1.4	-0.3	0.6	1.6
Back pain experienced in last month	0.3	0.4	2.2	0.2	-0.2	0.8	0.0	1.5	0.0	-0.4	0.8	0.3	-0.4
Medication: Gliclazide	0.3	0.3	1.5	0.3	0.4	0.7	-0.0	-1.2	0.6	-0.0	0.6	0.5	0.0
Number of self-reported non-cancer illnesses	0.3	0.5	1.0	0.6	0.0	0.8	0.5	-0.2	1.0	0.7	0.8	0.9	0.5
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.1	-0.8	-0.5	0.3	-0.1	1.0	-0.4	-0.8	0.6	0.1	-1.0
Number of operations (self-reported)	0.3	0.5	2.4	0.2	0.6	-0.2	0.7	-1.6	0.3	0.6	-0.3	0.1	0.8
Average weekly beer plus cider intake	0.3	0.5	2.1	0.1	0.5	0.4	1.4	-1.0	0.4	-0.4	0.8	0.5	-0.2
Vascular/heart problems diagnosed by doctor	0.3	1.0	1.6	-1.1	-1.1	-0.7	0.5	0.8	-1.2	-1.3	-0.7	-1.1	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.7	-0.8	-0.8	-0.4	-0.8	0.4	-0.6	-0.4	-0.2	-0.5	-0.7
Neuroticism (Nagel 2018)	0.2	0.4	3.2	-0.1	0.0	0.5	-0.3	-1.8	0.4	0.2	0.2	0.2	0.4
Ovarian Cancer	0.2	0.2	0.7	-0.7	-0.4	-0.5	0.1	0.9	-0.2	0.1	-0.6	-0.4	-0.2
HDL Cholesterol	0.2	0.3	0.9	0.3	0.3	0.1	-0.4	0.9	0.6	0.9	-0.1	0.4	0.9
Neuroticism (2016)	0.2	0.3	0.8	0.0	0.2	0.9	-0.2	-0.1	0.8	0.3	0.7	0.6	0.9
Schizophrenia (2014)	0.2	0.4	1.1	0.4	0.1	-1.0	0.1	-1.0	0.4	1.0	-0.6	0.1	0.8
Heel T-Score	0.2	1.9	14.1	-0.5	-0.4	-0.2	1.3	3.8	-0.6	-0.9	0.2	-0.4	-1.1
Hypothyroidism (self reported)	0.2	0.5	1.6	-0.5	-0.5	-0.2	1.3	-1.1	-0.1	-0.7	0.1	-0.1	-0.8
Neuroticism	0.2	0.4	0.9	0.5	0.8	0.6	1.0	-0.0	0.4	0.7	0.3	0.3	0.8
Hearing difficulty/problems: Yes	0.2	0.3	0.7	-0.8	-0.6	0.6	-0.7	-0.1	0.2	-0.5	0.7	0.3	-0.4
Trunk fat percentage	0.2	0.8	3.0	0.4	0.2	-0.4	0.4	-1.7	0.8	1.2	-0.5	0.4	1.4
Stomach or abdominal pain in last month	0.2	0.2	0.5	-0.7	-0.7	-0.0	-0.3	-0.3	-0.4	-0.1	-0.4	-0.5	-0.4
Medication: Levothyroxine sodium	0.2	0.4	1.2	-0.7	-0.7	0.1	-0.3	-0.6	-0.1	-1.1	0.5	0.1	-1.1
Trunk fat mass	0.2	0.8	3.5	-0.5	-0.7	-1.0	-0.2	-1.9	0.0	0.4	-1.2	-0.5	0.9
Hearing difficulty/problems with background noise	0.2	0.3	1.3	-0.9	-0.7	-0.4	-1.1	-0.1	-0.2	-0.5	-0.1	-0.2	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.3	0.7	0.9	-0.2	0.1	1.2	0.4	0.9	-0.3	0.1	0.9
Mouth/teeth dental problems	0.2	0.3	1.1	0.6	0.2	-0.1	0.8	-1.0	0.5	0.7	-0.2	0.1	0.6
Diabetes (self-reported)	0.2	0.3	0.9	0.8	0.7	0.6	0.5	-1.0	0.4	0.4	0.4	0.6	0.1
Illnesses of siblings	0.2	0.2	0.5	-0.6	-0.7	-0.5	-0.6	0.2	-0.4	-0.3	-0.4	-0.4	-0.6
Arm fat percentage (right)	0.2	0.8	2.0	0.8	0.6	-0.3	0.9	-1.0	0.9	1.2	-0.3	0.6	1.4
Falls in the last year	0.2	0.3	0.9	-0.1	0.0	0.8	0.2	0.9	0.5	-0.2	0.9	0.6	-0.1
Number of live births	0.2	0.3	2.1	0.4	-0.1	-0.1	-0.8	-1.5	-0.0	0.6	-0.2	0.0	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.4	0.2	0.0	0.8	-0.4	0.5	0.5	0.4	0.7	0.1
Arm fat mass (right)	0.2	0.6	1.8	-0.6	-0.9	-1.2	-0.3	-0.9	-0.3	0.1	-1.3	-0.8	0.7
Birth weight of first child	0.2	0.3	0.9	0.0	0.6	-0.5	-0.9	-0.2	0.0	0.5	-0.6	-0.3	0.8
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.5	-0.4	-0.6	-0.7	-0.2	0.6	-0.4	-0.6	-0.3	-0.5	-0.5
High blood pressure (siblings)	0.2	0.2	1.4	-0.2	-0.2	0.2	-1.2	-0.6	-0.0	-0.4	0.1	-0.0	-0.5
Body fat percentage	0.2	0.7	2.8	0.5	0.3	-0.2	0.5	-1.7	0.9	1.1	-0.2	0.5	1.3
Worry too long after embarrassment	0.2	0.3	1.3	-0.3	-0.4	1.1	-0.3	0.9	-0.1	-0.2	0.7	0.2	-0.5
Shortness of breath walking on level ground	0.2	0.3	1.4	-0.4	-0.5	0.5	0.3	-1.2	-0.0	-0.3	0.4	0.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.7	0.2	0.1	0.6	0.1	-0.4	0.4	-0.4	0.9	0.6	-0.3
Medication for pain relief, constipation, heartburn	0.2	0.4	2.6	0.1	0.4	0.5	-0.6	1.6	0.1	0.0	0.3	0.2	0.4
Medication: Ibuprofen	0.2	0.2	0.7	0.4	-0.1	-0.2	0.2	-0.8	0.4	0.7	0.0	0.4	0.2
Whole body fat mass	0.2	0.7	2.3	-0.8	-0.9	-1.1	-0.4	-1.5	-0.2	0.1	-1.2	-0.6	0.6
Leg fat mass (right)	0.2	0.8	1.8	-0.7	-1.0	-1.2	-0.1	-1.4	-0.5	-0.2	-1.3	-0.8	0.5
Chest pain or discomfort	0.2	0.2	1.6	0.1	0.2	0.2	-0.1	-1.2	0.2	0.3	0.0	0.1	0.6
Leg pain on walking	0.2	0.3	0.7	-0.2	-0.0	-0.9	0.3	-0.8	-0.4	0.1	-0.7	-0.6	-0.0
Medication: Aspirin	0.2	0.2	1.6	-0.3	-0.1	0.1	0.4	-1.3	0.0	-0.6	0.3	0.0	-0.2
Hypertension (Self-reported)	0.2	0.5	0.9	0.8	0.9	0.4	-0.3	-1.0	0.8	0.9	0.3	0.7	0.7
Ever had bowel cancer screening	0.2	0.2	0.6	0.6	0.7	0.1	0.0	0.6	0.2	0.6	-0.3	-0.0	0.3
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.7	0.6	0.7	0.5	-0.7	0.5	0.2	0.7	0.8	-0.2
Medication: Aspirin	0.2	0.3	1.9	-0.4	-0.2	0.1	0.1	-1.4	-0.0	-0.6	0.4	0.0	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.2	0.8	-0.2	-0.1	-0.5	-0.9	-0.6	-0.3	-0.2	-0.4	-0.3	-0.3
Arm fat mass (left)	0.2	0.8	1.9	-0.6	-0.9	-1.3	-0.6	-1.1	-0.3	0.2	-1.4	-0.7	0.7
Average weekly champagne plus white wine intake	0.2	0.3	1.3	-0.5	-0.5	0.3	-1.1	0.3	-0.0	-0.4	0.4	0.1	-0.4
Pain experienced in last month	0.2	0.3	1.1	0.8	1.1	-0.0	0.4	0.1	0.2	0.7	-0.3	0.1	0.5
Supplements: Calcium	0.2	0.3	0.8	0.8	0.2	0.2	0.9	0.5	0.3	0.9	0.0	0.2	-0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.5	-0.7	-0.4	-0.6	-0.3	-0.7	-0.7	-0.5	-0.4	-0.5	-0.6
Heart disease (siblings)	0.2	0.2	1.6	0.2	0.0	0.2	1.3	0.2	0.2	0.2	0.3	0.2	0.2
Alcohol drinker status: Previous	0.2	0.2	0.9	0.3	-0.1	0.2	1.0	0.7	-0.5	-0.3	0.1	-0.4	0.2
Leg fat mass (left)	0.2	0.7	1.6	-0.7	-1.1	-1.2	0.0	-1.1	-0.4	-0.1	-1.3	-0.8	0.5
Schizophrenia (2018)	0.1	0.2	0.7	-0.3	-0.5	-0.8	-0.5	-0.6	0.1	0.2	-0.4	-0.2	0.3
Worry (Nagel 2018)	0.1	0.3	1.0	0.2	0.7	0.5	0.3	-1.0	0.4	0.2	0.5	0.4	0.5
Age at First Birth	0.1	0.1	0.6	0.0	0.4	0.2	0.5	0.8	0.1	-0.3	0.3	0.2	-0.4
Mean Putamen Volume	0.1	0.1	0.4	-0.4	-0.2	0.3	0.4	-0.3	-0.1	-0.6	0.4	0.0	-0.1
Blood Eosinophil Count	0.1	0.4	1.8	-0.2	0.5	-0.6	1.3	0.5	0.2	0.6	-0.4	-0.2	0.8
Systolic Blood Pressure	0.1	0.7	1.3	0.4	0.8	0.9	-1.0	0.5	1.1	0.2	1.0	1.1	0.6
Cardiovascular Disease	0.1	0.3	1.8	0.4	0.2	0.3	-0.4	-1.3	0.5	0.3	0.3	0.4	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	0.3	0.0	0.4	0.2	-0.6	0.1	-0.5	0.5	0.4	-0.7
Lung FVC	0.1	0.3	1.0	-1.0	-0.8	0.1	-0.3	0.3	-0.7	-0.6	0.1	-0.4	-0.8
Chronotype (morning person)	0.1	0.3	1.2	0.8	1.1	-0.3	0.3	-0.3	0.2	0.3	-0.2	0.1	0.7
Sensitivity / hurt feelings	0.1	0.2	0.7	-0.1	-0.1	0.8	0.7	0.2	0.3	0.2	0.6	0.3	0.1
Current tobacco smoking	0.1	0.1	0.9	0.3	0.0	0.3	-0.4	-0.9	0.0	-0.1	0.3	0.2	0.2
Maternal smoking around birth	0.1	0.2	1.6	-0.0	0.2	-0.0	-0.6	-1.3	-0.1	-0.2	-0.1	-0.0	-0.0
Supplements: Glucosamine	0.1	0.2	1.2	-0.3	-0.1	-0.3	-0.3	-1.1	0.1	0.5	-0.4	-0.1	0.3
Body mass index (BMI)	0.1	0.5	1.6	-0.4	-0.8	-1.2	0.0	-0.7	-0.3	0.2	-1.3	-0.7	0.6
Hair/balding pattern: Pattern 2	0.1	0.2	1.3	0.2	-0.3	0.1	1.1	0.5	0.2	0.3	0.1	0.2	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.8	0.1	0.1	0.1	0.5	-0.9	0.1	0.4	0.1	0.2	0.1
Happiness	0.1	0.1	0.5	0.3	0.5	-0.1	0.7	-0.3	-0.1	0.3	-0.1	-0.1	-0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	1.1	-0.0	-0.2	0.1	0.4	1.1	-0.1	-0.0	0.1	-0.0	0.2
Leg fat percentage (right)	0.1	0.5	1.4	0.7	0.3	0.1	0.7	-1.2	0.8	0.5	0.1	0.5	1.2
Exposure to tobacco smoke outside home	0.1	0.2	0.3	0.3	0.1	0.4	-0.5	0.3	0.4	0.5	0.5	0.5	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.6	-0.4	-0.4	-0.3	-0.3	0.3	-0.3	-0.4	-0.2	-0.4	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.6	0.3	0.2	-0.8	0.2	-0.4	-0.3	0.2	-0.6	-0.3	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.5	-0.1	0.2	-0.2	-0.7	0.7	-0.2	0.5	-0.5	-0.4	0.1
Smoking status: Current	0.1	0.2	2.0	0.1	-0.2	0.1	-0.2	-1.4	-0.2	-0.3	0.1	-0.1	0.1
Financial situation satisfaction	0.1	0.2	1.1	0.3	0.3	-0.3	0.0	-1.1	0.0	0.5	-0.1	0.1	-0.1
Commuting to job workplace: Public transport	0.1	0.2	0.8	-0.5	0.3	0.4	-0.3	0.9	-0.3	-0.2	0.1	-0.3	-0.3
Medication: Bendroflumethiazide	0.1	0.2	1.0	-0.4	-0.4	0.1	0.4	-0.3	-0.4	-1.0	0.2	-0.2	-0.7
Illnesses of father: High blood pressure	0.1	0.2	0.7	0.1	-0.3	-0.4	0.8	0.5	-0.3	-0.4	-0.2	-0.3	0.1
Leg fat percentage (left)	0.1	0.4	1.4	0.6	0.3	0.0	0.7	-0.9	0.8	0.6	0.0	0.5	1.2
Fractured/broken bones in last 5 years	0.1	0.1	0.5	-0.6	-0.1	0.1	-0.5	-0.7	0.1	-0.6	0.2	-0.1	-0.1
Ever depressed for a whole week	0.1	0.2	0.6	0.3	0.2	0.8	-0.4	-0.2	0.4	-0.1	0.7	0.5	0.0
BMI	0.0	0.2	0.5	0.0	-0.4	-0.5	0.6	-0.4	0.3	0.4	-0.6	0.1	0.7
Hair Pigment	0.0	0.4	0.8	-0.6	-0.3	-0.8	-0.5	-0.1	-0.8	0.0	-0.9	-0.8	-0.6
Tanning	0.0	0.2	0.9	0.5	0.2	-0.2	0.9	0.1	0.5	0.6	-0.1	0.2	0.5
Relative age of first facial hair	0.0	0.1	0.4	0.3	0.1	0.1	0.7	-0.4	0.1	0.2	0.0	0.1	-0.0
Tense / ‘highly strung’	0.0	0.1	0.4	-0.6	0.0	0.1	0.1	-0.5	-0.1	-0.3	0.0	-0.2	-0.2

Hub : Genes

APOBEC3D

Models

Trait associations