Best TWAS P=4.29e-08 · Best GWAS P=5.1e-09 conditioned to 0.0391
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | MMAB | 0.07 | 0.06 | enet | 9 | 0.05 | 7.3e-05 | 5.2 | -5.5 | 4.3e-08 | -0.91 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MMAB | 0.03 | 0.02 | blup | 57 | 0.02 | 2.2e-03 | 5.0 | -5.1 | 3.0e-07 | -0.74 | 0.01 | 0.80 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | KCTD10 | 0.15 | 0.08 | lasso | 6 | 0.08 | 2.1e-08 | 5.0 | -5.4 | 5.9e-08 | -0.90 | 0.04 | 0.96 | FALSE |