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chr19:32,151,452-33,668,090

Best TWAS P=2.06e-11 · Best GWAS P=1.1e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DPY19L3 0.07 0.05 lasso 2 0.06 8.7e-08 -6.3 -6.7 2.7e-11 0.94 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts DPY19L3 0.19 0.12 lasso 6 0.10 9.4e-08 -6.3 -6.7 2.1e-11 0.95 0.02 0.98 TRUE
3 GTEx Esophagus Mucosa ZNF507 0.10 0.02 lasso 3 0.01 9.1e-02 -4.7 -5.4 7.1e-08 0.74 0.05 0.86 FALSE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPY19L3 0.04 0.03 blup 60 0.02 2.2e-03 -6.4 -5.6 1.9e-08 0.91 0.01 0.95 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF507 0.04 0.02 blup 38 0.03 1.0e-04 -6.4 -5.6 1.9e-08 0.86 0.01 0.99 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma DPY19L3 0.05 0.06 blup 62 0.05 1.3e-06 -6.4 -6.1 1.2e-09 0.87 0.01 0.99 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF507 0.05 0.03 blup 39 0.05 1.3e-06 -5.9 -6.0 1.9e-09 0.81 0.01 0.99 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma DPY19L3 0.02 0.02 blup 60 0.02 3.8e-03 -4.5 -5.3 9.0e-08 0.80 0.02 0.71 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DPY19L3 0.04 0.04 lasso 1 0.03 7.5e-05 -6.4 -6.4 1.4e-10 1.00 0.01 0.99 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma DPY19L3 0.04 0.05 blup 60 0.03 6.1e-04 -6.3 -6.2 4.7e-10 0.88 0.02 0.97 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma DPY19L3 0.05 0.04 enet 9 0.05 2.1e-05 -6.3 -6.3 2.2e-10 0.96 0.01 0.98 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ZNF507 0.14 0.14 lasso 5 0.18 2.4e-17 -6.4 -6.7 2.6e-11 0.90 0.00 1.00 FALSE