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chr20:43,958,786-45,456,440

Best TWAS P=9.36e-11 · Best GWAS P=1.82e-11 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CD40	0.10	0.01	blup	63	0.09	5.8e-06	-5.0	-6.5	9.4e-11	-0.58	0.25	0.19	TRUE
5	ROSMAP	Brain Pre-frontal Cortex	SLC12A5	0.24	0.24	lasso	6	0.24	5.4e-30	6.7	6.3	3.2e-10	0.98	0.00	1.00	TRUE
11	The Cancer Genome Atlas	Thyroid Carcinoma	CD40	0.03	0.00	blup	63	0.01	1.4e-02	-5.0	-6.4	1.3e-10	-0.67	0.04	0.26	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CD40	0.04	0.02	enet	10	0.04	2.2e-05	-5.3	-6.3	2.8e-10	-0.57	0.28	0.53	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	CD40	0.08	0.06	blup	63	0.09	4.4e-10	5.6	-6.3	3.0e-10	-0.75	0.01	0.99	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	CD40	0.06	0.05	blup	63	0.06	3.3e-12	5.8	-6.2	5.8e-10	-0.76	0.24	0.76	FALSE
2	GTEx	Nerve Tibial	CD40	0.13	0.01	lasso	5	0.02	1.4e-02	5.7	-6.0	1.8e-09	-0.80	0.02	0.93	FALSE
4	METSIM	Adipose	CD40	0.07	0.04	lasso	4	0.05	3.5e-08	5.9	-5.9	4.3e-09	-0.75	0.04	0.96	FALSE
1	GTEx	Cells Transformed fibroblasts	CD40	0.25	0.11	lasso	6	0.15	3.5e-11	-4.8	-5.8	7.7e-09	-0.48	0.39	0.59	FALSE
3	GTEx	Skin Sun Exposed Lower leg	CD40	0.13	0.08	lasso	3	0.08	4.1e-07	-5.0	-5.7	1.5e-08	-0.40	0.79	0.16	FALSE
10	The Cancer Genome Atlas	Stomach Adenocarcinoma	CD40	0.06	0.01	blup	63	0.04	6.7e-04	6.0	-5.6	1.7e-08	-0.61	0.05	0.51	FALSE