Best TWAS P=7.61e-35 · Best GWAS P=1.38e-39 conditioned to 1.85e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | AUH | 0.14 | 0.06 | enet | 15 | 0.11 | 1.2e-13 | -9.20 | -12.3 | 7.6e-35 | 0.74 | 0.95 | 0.05 | TRUE |
| 2 | GTEx | Whole Blood | RP11-305L7.1 | 0.10 | 0.06 | lasso | 7 | 0.06 | 1.4e-06 | -7.91 | 8.6 | 7.6e-18 | -0.38 | 0.99 | 0.00 | FALSE |
| 3 | METSIM | Adipose | RP11-305L7.1 | 0.08 | 0.03 | blup | 545 | 0.05 | 1.5e-08 | -9.73 | 7.0 | 3.1e-12 | -0.66 | 0.04 | 0.96 | FALSE |
| 4 | YFS | Blood | NFIL3 | 0.02 | 0.01 | enet | 23 | 0.01 | 1.4e-04 | 0.88 | 5.5 | 4.9e-08 | -0.26 | 0.11 | 0.03 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | AUH | 0.05 | 0.06 | lasso | 4 | 0.05 | 8.5e-07 | -9.48 | -9.6 | 5.5e-22 | 0.55 | 0.86 | 0.06 | FALSE |