[Hub]/) : Traits : Blood Eosinophil Count :

chr9:85,657,836-87,315,117

Best TWAS P=3.44e-15 · Best GWAS P=3.17e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RMI1 0.07 0.06 lasso 3 0.06 1.4e-07 7.6 -7.6 2.8e-14 -0.98 0.01 0.99 FALSE
2 GTEx Esophagus Mucosa GKAP1 0.09 0.06 lasso 2 0.02 2.9e-02 7.0 -7.0 2.5e-12 -0.68 0.31 0.47 FALSE
3 GTEx Muscle Skeletal GKAP1 0.07 0.04 enet 23 0.03 1.0e-03 7.0 -5.7 9.6e-09 -0.50 0.40 0.30 FALSE
4 YFS Blood GKAP1 0.02 0.01 blup 614 0.01 3.2e-04 7.3 -7.2 4.3e-13 -0.70 0.01 0.98 FALSE
5 YFS Blood RMI1 0.07 0.09 bslmm 528 0.09 1.5e-27 7.3 7.9 3.4e-15 0.95 0.03 0.97 TRUE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma UBQLN1 0.03 0.02 lasso 2 0.01 2.3e-02 5.4 -6.2 5.3e-10 -0.55 0.07 0.12 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma RMI1 0.02 0.02 blup 31 0.01 8.8e-04 7.5 -6.1 8.8e-10 -0.93 0.01 0.92 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RMI1 0.03 0.03 lasso 4 0.04 4.1e-05 7.4 -6.1 8.4e-10 -0.92 0.01 0.96 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma RMI1 0.03 0.03 blup 31 0.01 1.2e-02 7.7 -7.1 1.6e-12 -0.97 0.01 0.97 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma UBQLN1 0.13 0.09 blup 60 0.10 4.9e-05 -2.7 -5.2 2.3e-07 -0.31 0.27 0.04 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma GKAP1 0.05 0.06 lasso 3 0.06 1.2e-06 7.0 -7.0 2.0e-12 -0.73 0.39 0.60 FALSE