[Hub]/) : Traits : Blood Eosinophil Count :

chr11:56,306,839-58,178,587

Best TWAS P=1.06e-12 · Best GWAS P=7.24e-28 conditioned to 1.87e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex APLNR 0.07 0.01 enet 29 0.04 1.6e-05 -5.62 -5.9 3.7e-09 -0.33 0.41 0.02 TRUE
2 GTEx Artery Tibial MED19 0.22 0.12 enet 37 0.16 6.6e-13 -2.82 -6.8 8.9e-12 -0.20 1.00 0.00 FALSE
3 GTEx Colon Transverse MED19 0.10 0.00 enet 28 0.08 1.4e-04 -2.82 -5.7 9.2e-09 0.03 0.29 0.04 FALSE
4 GTEx Esophagus Mucosa MED19 0.14 0.07 lasso 4 0.11 5.9e-08 6.77 -6.4 1.4e-10 0.03 1.00 0.00 FALSE
5 GTEx Lung MED19 0.12 0.00 enet 12 0.06 2.9e-05 -2.82 -6.1 1.2e-09 0.00 0.60 0.02 FALSE
6 GTEx Nerve Tibial MED19 0.12 0.00 enet 25 0.02 2.1e-02 -2.76 -5.4 7.4e-08 0.04 0.71 0.02 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic MED19 0.12 0.05 enet 31 0.05 7.5e-04 4.83 -5.9 3.5e-09 0.08 0.57 0.02 FALSE
8 GTEx Skin Sun Exposed Lower leg MED19 0.15 0.11 lasso 7 0.09 1.3e-07 4.87 -5.6 2.5e-08 0.11 1.00 0.00 FALSE
9 GTEx Thyroid MED19 0.11 0.02 lasso 12 0.07 3.2e-06 6.81 -7.1 1.1e-12 0.00 0.91 0.00 TRUE
10 GTEx Vagina MED19 0.26 0.03 lasso 10 0.06 1.5e-02 -3.25 -5.3 9.8e-08 0.02 0.12 0.09 FALSE
11 ROSMAP Brain Pre-frontal Cortex SLC43A3 0.04 0.01 enet 16 0.02 2.7e-03 1.12 -5.8 7.9e-09 -0.50 0.14 0.34 FALSE
12 ROSMAP Brain Pre-frontal Cortex ZDHHC5 0.05 0.02 blup 401 0.03 2.0e-04 3.96 -5.2 1.5e-07 0.06 0.38 0.02 FALSE
13 YFS Blood MED19 0.47 0.18 enet 73 0.28 7.1e-93 -2.71 -5.3 9.4e-08 0.00 1.00 0.00 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LRRC55 0.10 0.01 blup 62 0.04 1.2e-05 0.04 6.0 1.7e-09 0.26 0.01 0.20 TRUE