[Hub]/) : Traits : Blood Eosinophil Count :

chr12:52,369,300-53,772,927

Best TWAS P=1.23e-10 · Best GWAS P=2.33e-10 conditioned to 0.277

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose KRT1 0.21 0.18 bslmm 787 0.18 1.4e-26 5.7 5.4 5.6e-08 0.84 0.02 0.98 FALSE
2 The Cancer Genome Atlas Breast Invasive Carcinoma KRT1 0.27 0.35 lasso 5 0.34 2.0e-73 5.7 5.8 6.0e-09 0.84 0.07 0.93 FALSE
3 The Cancer Genome Atlas Colon Adenocarcinoma KRT1 0.25 0.29 lasso 6 0.30 1.5e-17 5.7 5.9 2.9e-09 0.84 0.02 0.98 FALSE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KRT1 0.32 0.36 lasso 3 0.35 1.9e-41 5.7 5.8 6.8e-09 0.85 0.07 0.93 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KRT2 0.28 0.09 enet 19 0.18 8.9e-20 6.3 5.3 1.3e-07 0.71 0.00 1.00 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KRT73 0.07 0.04 enet 5 0.05 7.1e-06 6.3 6.4 1.2e-10 0.92 0.00 1.00 TRUE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma KRT1 0.22 0.26 lasso 5 0.26 5.3e-15 5.7 5.7 1.6e-08 0.84 0.03 0.97 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma KRT1 0.35 0.44 lasso 4 0.44 1.5e-55 5.7 5.8 6.2e-09 0.84 0.06 0.94 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KRT1 0.06 0.00 blup 93 0.01 2.7e-02 -3.0 5.5 3.3e-08 0.60 0.01 0.85 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma KRT1 0.35 0.43 enet 12 0.44 3.6e-20 6.0 6.1 1.3e-09 0.85 0.01 0.99 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma KRT1 0.21 0.15 lasso 3 0.16 9.6e-07 5.7 6.0 2.4e-09 0.87 0.02 0.98 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma KRT1 0.26 0.40 lasso 3 0.40 3.3e-44 5.7 5.7 9.4e-09 0.84 0.06 0.94 FALSE
13 The Cancer Genome Atlas Rectum Adenocarcinoma KRT1 0.45 0.35 enet 19 0.27 4.0e-07 6.0 6.3 3.0e-10 0.78 0.02 0.98 FALSE
14 The Cancer Genome Atlas Soft Tissue Sarcoma KRT1 0.17 0.16 enet 15 0.16 6.2e-10 6.1 5.8 7.2e-09 0.77 0.01 0.99 FALSE
15 The Cancer Genome Atlas Stomach Adenocarcinoma KRT1 0.17 0.24 lasso 3 0.23 9.3e-17 5.7 6.0 1.5e-09 0.91 0.01 0.99 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma KRT1 0.12 0.09 lasso 5 0.08 2.0e-08 5.7 5.9 4.6e-09 0.84 0.02 0.98 FALSE