Best TWAS P=1.38e-09 · Best GWAS P=4.01e-09 conditioned to 0.000885
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DIP2B | 0.11 | 0.10 | enet | 16 | 0.13 | 2.6e-15 | -5.9 | -5.7 | 1.4e-08 | 0.89 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Testis | SLC11A2 | 0.17 | 0.13 | enet | 11 | 0.12 | 9.2e-06 | 4.3 | 6.1 | 1.4e-09 | -0.49 | 0.35 | 0.60 | TRUE |
| 3 | NTR | Blood | ATF1 | 0.06 | 0.07 | enet | 35 | 0.07 | 4.0e-21 | -5.2 | -5.5 | 4.4e-08 | 0.88 | 0.10 | 0.90 | FALSE |
| 4 | YFS | Blood | ATF1 | 0.05 | 0.07 | lasso | 9 | 0.07 | 2.0e-21 | -5.2 | -5.4 | 5.8e-08 | 0.95 | 0.09 | 0.91 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ATF1 | 0.03 | 0.04 | lasso | 1 | 0.04 | 6.3e-05 | -5.2 | 5.2 | 2.0e-07 | -0.91 | 0.02 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LETMD1 | 0.03 | 0.02 | lasso | 4 | 0.02 | 1.9e-03 | 4.8 | -5.2 | 2.4e-07 | 0.39 | 0.00 | 0.89 | FALSE |