TWAS hub - KRT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Whole Blood	0.1950	0.0530	3.5e-05	0.049	NA	0.054	NA	0.050	2.2e-05	NA	9.0e-06	NA	1.9e-05
2	METSIM	Adipose	0.2100	0.0381	2.2e-16	0.183	0.141	0.178	0.183	0.182	1.3e-26	2.0e-20	5.9e-26	1.4e-26	1.7e-26
3	NTR	Blood	0.2686	0.0290	0.0e+00	0.168	0.218	0.276	0.276	0.261	6.0e-52	1.4e-68	1.5e-89	2.8e-89	6.6e-84
4	TCGA	Breast Invasive Carcinoma	0.2700	0.0511	0.0e+00	0.348	0.323	0.330	NA	0.344	1.5e-74	5.7e-68	6.7e-70	NA	2.0e-73
5	TCGA	Colon Adenocarcinoma	0.2530	0.0590	1.1e-16	0.294	0.259	0.274	NA	0.297	2.5e-17	3.6e-15	4.2e-16	NA	1.5e-17
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.3233	0.0721	0.0e+00	0.361	0.317	0.350	NA	0.354	2.5e-42	2.1e-36	8.5e-41	NA	1.9e-41
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2210	0.0580	1.8e-12	0.264	0.197	0.205	NA	0.258	2.3e-15	1.7e-11	6.3e-12	NA	5.3e-15
8	TCGA	Lung Adenocarcinoma	0.3496	0.0644	0.0e+00	0.444	0.397	0.411	NA	0.435	4.0e-57	1.9e-49	9.9e-52	NA	1.5e-55
9	TCGA	Lung Squamous Cell Carcinoma	0.0647	0.0302	2.3e-03	0.002	0.009	0.009	NA	0.001	2.0e-01	2.7e-02	2.9e-02	NA	2.2e-01
10	TCGA	Pancreatic Adenocarcinoma	0.3540	0.0740	4.4e-16	0.431	0.338	0.439	NA	0.436	1.1e-19	6.8e-15	3.6e-20	NA	5.7e-20
11	TCGA	Pheochromocytoma and Paraganglioma	0.2130	0.0830	4.3e-05	0.150	0.100	0.050	NA	0.155	1.5e-06	8.5e-05	4.9e-03	NA	9.6e-07
12	TCGA	Prostate Adenocarcinoma	0.2584	0.0536	0.0e+00	0.403	0.345	0.383	NA	0.397	4.6e-45	3.0e-37	2.3e-42	NA	3.3e-44
13	TCGA	Rectum Adenocarcinoma	0.4510	0.1000	2.0e-07	0.347	0.188	0.273	NA	0.100	5.5e-09	3.5e-05	4.1e-07	NA	2.5e-03
14	TCGA	Soft Tissue Sarcoma	0.1710	0.0530	1.4e-08	0.157	0.134	0.163	NA	0.163	1.4e-09	2.4e-08	6.1e-10	NA	6.4e-10
15	TCGA	Stomach Adenocarcinoma	0.1700	0.0520	1.4e-12	0.236	0.181	0.223	NA	0.232	4.1e-17	4.1e-13	4.2e-16	NA	9.3e-17
16	TCGA	Thyroid Carcinoma	0.1150	0.0420	6.0e-08	0.094	0.066	0.060	NA	0.082	1.8e-09	5.7e-07	1.6e-06	NA	2.0e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Allergy	8.6	19.8	28.9	-3.5	-4.3	-4.1	-4.6	-4.6	-4.7	-4.7	-4.6	-3.2	-4.5	-4.5	-4.6	-5.4	-4.3	-4.5	-4.7
Hayfever, allergic rhinitis or eczema	6.2	13.4	16.8	2.5	3.5	3.0	3.8	3.8	3.9	3.9	3.8	3.1	3.8	3.8	3.8	4.1	3.7	3.9	3.9
Diabetes (self-reported)	6.0	9.2	11.4	-2.5	-3.2	-2.3	-3.2	-3.1	-3.3	-3.3	-3.2	-2.0	-3.1	-3.3	-3.3	-2.6	-3.2	-3.4	-3.3
Hearing aid user	5.8	6.5	8.4	-2.4	-2.7	-2.3	-2.7	-2.7	-2.7	-2.7	-2.7	-1.3	-2.9	-2.8	-2.7	-2.4	-2.2	-2.7	-2.7
Alzheimer’s Disease (including proxy)	5.5	7.9	9.5	2.0	2.8	2.6	3.0	3.0	2.9	3.0	3.0	2.2	2.9	2.8	3.0	3.0	2.8	2.7	3.1
Gout (self-reported)	5.2	7.1	8.7	-1.6	-2.6	-1.8	-2.8	-2.8	-2.8	-2.8	-2.8	-2.8	-2.9	-2.9	-2.8	-2.4	-2.5	-2.8	-2.9
Allergy or Eczema	5.1	13.5	17.6	1.5	3.6	2.6	3.9	3.9	3.9	3.9	3.9	3.4	3.9	3.9	3.8	4.0	4.2	3.8	3.9
Eye problems/disorders: Diabetes related eye disease	5.1	5.6	7.5	-2.2	-2.7	-2.1	-2.5	-2.5	-2.5	-2.5	-2.5	-0.9	-2.6	-2.5	-2.5	-2.0	-2.3	-2.5	-2.6
Alzheimer’s Disease (in mother)	4.7	5.5	7.6	1.8	2.4	1.7	2.5	2.5	2.5	2.5	2.5	1.6	2.4	2.4	2.5	2.8	2.3	2.4	2.6
Medication: Metformin	4.4	6.2	7.5	-2.5	-2.6	-2.3	-2.6	-2.5	-2.6	-2.6	-2.5	-1.4	-2.6	-2.7	-2.6	-2.3	-2.5	-2.7	-2.6
Blood Eosinophil Count	4.2	32.1	39.7	3.5	5.4	4.8	5.8	5.9	5.8	5.7	5.8	5.5	6.1	6.0	5.7	6.3	5.8	6.0	5.9
Medication for hormone replacement therapy	4.2	4.7	6.6	1.1	2.0	1.8	2.3	2.3	2.3	2.3	2.3	2.1	2.2	2.2	2.2	2.6	2.3	2.3	2.3
Ever used hormone-replacement therapy (HRT)	4.0	5.2	6.8	0.8	2.3	1.8	2.4	2.4	2.4	2.5	2.4	2.0	2.3	2.2	2.4	2.6	2.3	2.3	2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.9	4.7	8.5	-1.9	-2.2	-1.9	-2.2	-2.3	-2.1	-2.0	-2.2	-1.1	-2.4	-2.2	-2.1	-2.9	-2.4	-2.2	-2.1
Breast cancer (self-reported)	3.9	4.7	6.3	-0.1	-2.1	-2.3	-2.4	-2.3	-2.4	-2.4	-2.4	-1.7	-2.4	-2.4	-2.4	-1.6	-1.9	-2.2	-2.5
Ever had bowel cancer screening	3.7	4.4	6.0	-1.9	-2.4	-1.2	-2.2	-2.2	-2.2	-2.2	-2.2	-1.7	-2.2	-2.2	-2.2	-1.7	-2.0	-2.5	-2.2
Had major operations	3.6	4.3	5.7	2.0	2.0	1.8	2.2	2.3	2.2	2.2	2.3	1.2	2.2	2.1	2.3	1.9	1.7	2.1	2.4
Diabetes (father)	3.4	4.2	6.3	1.6	2.2	2.5	2.1	2.2	2.0	2.0	2.1	1.3	2.2	2.0	2.1	2.3	2.1	1.9	2.0
Tinnitus: Yes, but not now, but have in the past	3.4	3.6	5.4	-1.4	-1.6	-2.1	-2.0	-2.0	-1.9	-2.0	-2.0	-1.7	-1.9	-1.8	-2.0	-2.3	-1.7	-1.9	-2.1
Medication: Ventolin 100micrograms inhaler	3.4	4.4	5.5	1.7	2.2	1.8	2.2	2.2	2.2	2.2	2.2	1.7	2.2	2.2	2.2	1.9	2.0	2.3	2.1
Maternal smoking around birth	3.3	4.8	8.9	3.0	2.0	2.8	1.9	2.0	1.9	1.8	1.9	1.9	2.4	2.3	1.9	2.7	2.5	1.8	1.9
Medication: Seretide 50 evohaler	3.1	3.6	4.9	1.4	2.1	0.9	2.1	2.2	2.1	2.1	2.2	-0.4	2.2	2.0	2.1	1.5	1.8	2.2	2.1
Illness, injury, bereavement, stress in last 2 years	3.1	3.7	5.0	2.1	1.9	1.9	2.1	2.0	2.1	2.1	2.1	0.7	1.9	2.1	2.0	1.7	1.3	2.2	2.0
Diabetes diagnosed by doctor	3.1	5.0	6.9	-2.0	-2.5	-1.3	-2.4	-2.3	-2.4	-2.4	-2.4	-1.3	-2.2	-2.5	-2.4	-1.7	-2.4	-2.6	-2.4
Serious illness, injury or assault to yourself	2.9	3.6	4.8	-1.5	-1.9	-1.2	-2.1	-2.1	-2.1	-2.2	-2.1	-0.8	-1.9	-2.0	-2.1	-1.4	-1.8	-2.0	-2.1
Illnesses of father: High blood pressure	2.9	3.6	4.6	-1.5	-1.8	-1.6	-2.1	-2.1	-2.0	-2.0	-2.1	-1.3	-2.0	-2.0	-2.0	-1.8	-1.8	-1.9	-2.1
Supplements: Zinc	2.7	3.0	8.7	0.7	1.1	-0.2	1.8	1.7	1.8	1.8	1.8	3.0	1.5	1.6	1.8	2.0	1.6	1.8	1.9
Financial difficulties in last 2 years	2.7	3.6	7.4	-2.0	-2.0	-2.7	-1.8	-1.9	-1.8	-1.7	-1.8	-1.8	-2.0	-1.8	-1.8	-2.1	-1.3	-1.8	-1.8
Medication: Omeprazole	2.7	3.2	5.2	1.9	1.9	1.5	1.8	1.9	1.8	1.8	1.8	0.0	1.9	1.9	1.8	2.3	1.7	1.8	1.8
Ovarian Cancer	2.6	3.5	4.1	-1.8	-1.9	-1.4	-2.0	-2.0	-2.0	-2.0	-2.0	-1.5	-2.0	-1.9	-1.9	-1.6	-1.7	-2.0	-2.0
Medication: Atorvastatin	2.6	3.3	5.1	-1.3	-2.0	-0.8	-1.9	-1.9	-1.9	-1.9	-1.8	-1.2	-1.9	-2.1	-1.8	-1.3	-2.2	-2.2	-1.9
Medication: Allopurinol	2.5	3.4	6.1	-0.7	-1.7	-1.1	-1.8	-1.8	-1.8	-1.8	-1.8	-2.5	-2.0	-2.1	-1.9	-1.7	-2.2	-1.8	-1.9
Hayfever/allergic rhinitis (self-reported)	2.4	3.2	4.5	0.7	1.8	1.5	1.8	1.9	1.8	1.8	1.8	1.0	2.1	2.0	1.9	1.7	2.1	1.9	1.9
Medication: Gliclazide	2.4	2.7	4.8	-1.7	-1.4	-1.6	-1.5	-1.5	-1.5	-1.4	-1.4	-2.2	-1.9	-1.9	-1.5	-1.6	-1.7	-1.6	-1.6
Tinnitus: Yes, now most or all of the time	2.4	2.8	4.5	-2.1	-1.8	-2.1	-1.7	-1.7	-1.7	-1.7	-1.7	-1.3	-1.8	-1.6	-1.7	-1.6	-0.7	-1.6	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.6	5.3	-1.7	-1.5	-1.1	-1.6	-1.7	-1.6	-1.5	-1.6	-1.6	-1.7	-1.7	-1.6	-1.6	-2.3	-1.7	-1.6
Age started oral contraceptive pill	2.3	2.9	3.7	-1.8	-1.8	-0.9	-1.8	-1.8	-1.8	-1.8	-1.8	-0.4	-1.8	-1.8	-1.8	-1.7	-1.6	-1.9	-1.8
Type 2 Diabetes (T2D) (2018)	2.1	4.0	5.2	-1.0	-2.1	-1.2	-2.1	-2.0	-2.1	-2.2	-2.1	-2.3	-2.0	-2.2	-2.2	-1.6	-2.0	-2.1	-2.2
Hair/balding pattern: Pattern 4	2.1	5.0	7.5	-2.6	-2.1	-1.3	-2.4	-2.4	-2.4	-2.3	-2.4	-1.0	-2.3	-2.3	-2.3	-2.7	-1.8	-2.3	-2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.4	8.5	2.9	2.0	2.5	2.0	1.9	2.0	1.9	1.9	1.4	2.1	2.2	1.9	2.3	1.9	2.3	1.9
Fed-up feelings	2.0	3.6	6.8	1.5	2.0	1.5	1.9	2.0	1.9	1.8	1.9	0.6	2.2	2.0	1.8	2.2	2.6	1.6	1.9
Illnesses of siblings: Diabetes	2.0	2.4	5.9	-0.3	-1.7	-1.3	-1.5	-1.4	-1.6	-1.5	-1.5	-2.4	-1.5	-1.6	-1.6	-1.5	-1.4	-1.6	-1.6
Headache pain in last month	1.9	3.3	4.0	1.7	1.9	1.9	1.8	1.8	1.9	1.9	1.8	1.2	1.9	1.9	1.9	1.7	2.0	1.7	1.9
Ever depressed for a whole week	1.9	2.3	6.2	0.9	1.6	1.3	1.4	1.3	1.4	1.4	1.3	1.3	1.7	1.7	1.5	1.5	2.5	1.4	1.5
Happiness	1.8	2.2	4.2	0.8	1.6	1.0	1.5	1.5	1.5	1.5	1.5	1.1	1.5	1.4	1.6	1.9	2.0	1.1	1.6
Medication: Cholesterol lowering	1.8	2.8	3.9	-1.4	-1.9	-1.1	-1.8	-1.7	-1.8	-1.8	-1.8	-0.5	-1.8	-1.9	-1.8	-1.1	-2.0	-1.9	-1.8
Chronic bronchitis/emphysema (mother)	1.8	2.1	4.6	2.1	1.3	1.2	1.4	1.4	1.4	1.4	1.4	1.0	1.5	1.5	1.4	1.5	1.4	1.3	1.4
Neck or shoulder pain in last month	1.8	2.5	5.3	-1.3	-1.6	-2.3	-1.5	-1.5	-1.4	-1.4	-1.4	-2.0	-1.9	-1.8	-1.4	-1.3	-1.4	-1.6	-1.4
Medication for cholesterol	1.8	2.7	3.8	-0.5	-1.6	-0.9	-1.9	-1.9	-1.8	-1.9	-1.9	-1.2	-1.7	-1.6	-1.9	-1.8	-1.5	-1.7	-1.9
Neuroticism (2016)	1.7	2.5	4.8	0.1	1.5	0.4	1.7	1.8	1.6	1.6	1.7	1.6	1.8	1.7	1.7	1.5	2.2	1.4	1.7
Qualifications: CSEs or equivalent	1.7	2.3	4.1	2.0	1.4	0.5	1.6	1.5	1.6	1.7	1.5	-0.3	1.4	1.6	1.6	1.3	1.9	1.6	1.6
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	5.1	-0.2	1.5	0.7	1.5	1.5	1.4	1.4	1.5	1.0	1.6	1.5	1.5	1.8	2.3	1.3	1.5
Mouth/teeth dental problems	1.7	2.6	3.8	-1.3	-1.7	-1.1	-1.8	-1.9	-1.8	-1.8	-1.9	-0.7	-1.6	-1.5	-1.8	-2.0	-1.0	-1.5	-1.9
Asthma	1.7	3.3	6.0	0.7	1.6	1.4	2.0	1.9	2.0	2.0	2.0	1.5	1.7	1.8	1.9	2.4	1.7	1.9	1.9
Ever highly irritable/argumentative for 2 days	1.7	2.1	6.4	0.9	1.1	1.6	1.4	1.4	1.3	1.3	1.4	1.6	1.5	1.3	1.4	2.5	0.9	1.3	1.5
Number of full brothers	1.7	2.2	2.9	-1.4	-1.6	-1.5	-1.5	-1.4	-1.5	-1.5	-1.5	-1.2	-1.4	-1.3	-1.6	-1.7	-1.3	-1.4	-1.6
Average weekly champagne plus white wine intake	1.7	2.3	3.1	-1.1	-1.1	-1.6	-1.5	-1.6	-1.5	-1.5	-1.5	-1.6	-1.6	-1.5	-1.6	-1.8	-1.5	-1.6	-1.6
Eye problems/disorders: None of the above	1.6	1.9	2.9	0.7	1.3	1.4	1.4	1.4	1.4	1.4	1.4	0.8	1.6	1.5	1.4	1.5	1.2	1.7	1.4
Asthma (self-reported)	1.6	3.2	5.7	0.7	1.6	1.4	1.9	1.8	1.9	1.9	1.9	1.7	1.6	1.7	1.9	2.4	1.6	1.9	1.9
Medication: Bendroflumethiazide	1.6	2.4	6.1	1.2	1.5	1.5	1.6	1.7	1.5	1.5	1.6	0.8	1.5	1.2	1.6	2.5	1.5	1.2	1.7
Taking other prescription medications	1.5	2.3	3.5	0.7	1.1	1.2	1.6	1.6	1.5	1.5	1.6	1.8	1.6	1.5	1.6	1.9	1.8	1.4	1.7
Multivitamins +/- minerals	1.5	1.9	2.5	0.8	1.5	1.0	1.5	1.4	1.5	1.5	1.5	0.3	1.5	1.5	1.5	1.3	1.6	1.6	1.5
Exposure to tobacco smoke at home	1.5	1.7	2.8	1.5	1.6	0.6	1.3	1.2	1.3	1.3	1.3	-0.3	1.2	1.3	1.3	1.5	1.7	1.3	1.3
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	3.6	1.9	1.2	1.1	1.4	1.4	1.4	1.4	1.4	0.7	1.4	1.4	1.4	1.4	0.5	1.5	1.5
Hearing difficulty/problems with background noise	1.4	2.3	5.8	-0.1	1.5	-0.3	1.7	1.6	1.7	1.7	1.7	-0.1	1.5	1.5	1.6	1.4	2.4	1.5	1.6
Time employed in main current job	1.4	1.6	2.1	-0.9	-1.3	-0.8	-1.3	-1.4	-1.3	-1.4	-1.4	-1.4	-1.3	-1.3	-1.3	-1.3	-1.3	-1.3	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	4.6	-0.1	1.3	0.9	1.4	1.5	1.4	1.4	1.4	1.5	1.6	1.6	1.5	1.3	2.1	1.5	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	3.9	1.2	1.2	1.4	1.3	1.4	1.2	1.2	1.3	1.0	1.5	1.3	1.3	2.0	1.7	1.2	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	3.4	0.2	1.1	0.9	1.4	1.4	1.4	1.4	1.4	0.8	1.4	1.3	1.4	1.8	1.2	1.3	1.4
Schizophrenia vs Biploar Disorder	1.3	1.8	3.2	0.4	1.4	1.1	1.5	1.4	1.5	1.5	1.5	0.5	1.3	1.4	1.5	0.9	1.8	1.4	1.4
Verbal and Numeric Reasoning (VNR)	1.3	3.1	6.6	2.6	1.8	2.3	1.6	1.7	1.6	1.6	1.7	0.8	1.8	1.6	1.7	2.1	1.3	1.6	1.7
Stomach or abdominal pain in last month	1.3	1.6	3.0	-0.1	1.1	1.1	1.3	1.4	1.3	1.3	1.3	1.0	1.4	1.2	1.4	1.5	1.7	1.2	1.4
Supplements: Glucosamine	1.3	1.6	2.9	-1.0	-1.2	-0.8	-1.4	-1.4	-1.4	-1.3	-1.4	-1.1	-1.4	-1.3	-1.3	-1.7	-1.0	-1.2	-1.3
Medication: Ramipril	1.3	1.7	2.8	0.4	1.2	0.7	1.4	1.4	1.4	1.5	1.5	1.7	1.3	1.3	1.5	0.7	1.1	1.3	1.5
Hypertension (Self-reported)	1.3	3.6	6.1	-1.3	-2.0	-2.0	-1.9	-1.8	-2.0	-2.0	-1.9	-2.5	-1.7	-2.0	-1.9	-1.4	-1.5	-2.1	-1.9
Smoking status: Current	1.3	2.1	3.0	0.8	1.5	1.6	1.4	1.5	1.4	1.3	1.4	1.7	1.6	1.5	1.4	1.7	1.4	1.3	1.4
Eye problems/disorders: Glaucoma	1.3	1.6	2.3	-0.3	-1.3	-0.7	-1.4	-1.4	-1.5	-1.5	-1.4	-0.7	-1.3	-1.5	-1.4	-1.1	-1.0	-1.5	-1.4
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	3.4	1.6	1.4	1.0	1.2	1.3	1.2	1.1	1.2	-0.8	1.4	1.3	1.1	1.8	1.3	1.2	1.1
Bipolar Disorder (2011)	1.2	1.2	1.5	-1.0	-1.1	-1.0	-1.2	-1.2	-1.2	-1.2	-1.2	-0.4	-1.1	-1.1	-1.2	-0.9	-0.8	-1.2	-1.2
Triglycerides	1.2	2.0	4.2	-2.1	-1.4	-1.6	-1.4	-1.5	-1.3	-1.3	-1.4	-0.1	-1.6	-1.4	-1.3	-1.5	-1.4	-1.4	-1.4
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	3.2	1.2	1.3	1.5	1.3	1.5	1.2	1.2	1.3	0.7	1.6	1.3	1.3	1.8	1.6	1.2	1.4
Illnesses of siblings	1.2	1.6	2.5	0.0	1.6	0.8	1.4	1.3	1.5	1.5	1.4	1.3	1.2	1.4	1.5	0.7	0.6	1.4	1.5
Shortness of breath walking on level ground	1.2	1.5	2.1	0.5	1.1	0.3	1.4	1.4	1.4	1.4	1.4	-0.6	1.2	1.2	1.4	1.3	1.2	1.3	1.4
Chest pain or discomfort	1.2	1.8	4.4	1.0	1.2	0.7	1.4	1.5	1.3	1.3	1.4	0.0	1.5	1.4	1.3	2.1	1.7	1.3	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.5	2.1	0.6	1.2	-0.5	1.4	1.3	1.4	1.4	1.4	0.7	1.1	1.3	1.4	0.9	1.4	1.3	1.4
Commuting to job workplace: Public transport	1.2	1.5	3.9	0.4	1.1	1.1	1.2	1.2	1.2	1.2	1.2	2.0	1.2	1.2	1.1	0.9	1.5	1.2	1.1
Systolic Blood Pressure	1.1	5.7	7.7	-1.4	-2.4	-2.8	-2.4	-2.4	-2.4	-2.3	-2.4	-2.5	-2.5	-2.5	-2.4	-2.5	-2.4	-2.4	-2.4
Trunk fat percentage	1.1	4.2	9.1	1.2	2.1	1.3	2.2	2.3	2.2	2.1	2.2	0.6	2.1	2.0	2.2	3.0	2.1	1.8	2.2
Average weekly fortified wine intake	1.1	1.3	5.7	-0.1	1.1	0.4	1.1	1.1	1.1	1.1	1.1	2.4	1.0	1.0	1.2	1.0	0.9	1.0	1.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.0	-0.8	-1.4	-1.4	-1.2	-1.1	-1.2	-1.3	-1.2	0.4	-1.0	-1.0	-1.2	-1.3	-0.6	-0.9	-1.3
Alcohol usually taken with meals	1.1	1.8	3.3	-1.8	-1.2	-0.7	-1.4	-1.5	-1.4	-1.4	-1.4	-0.4	-1.5	-1.5	-1.4	-1.3	-1.4	-1.2	-1.5
Leg pain on walking	1.1	1.4	3.7	-0.7	-1.1	-1.7	-1.1	-1.1	-1.0	-1.1	-1.1	-1.9	-1.1	-1.0	-1.0	-1.3	-0.7	-1.1	-1.0
Chronotype (morning person)	1.0	2.4	5.3	2.3	1.7	2.2	1.5	1.4	1.5	1.5	1.5	0.5	1.5	1.5	1.5	1.3	1.2	1.5	1.4
Impedance of arm (right)	1.0	4.6	13.0	1.0	1.8	1.4	2.1	2.1	2.1	2.1	2.1	3.6	2.0	2.0	2.1	2.5	1.7	2.2	2.2
Arm fat percentage (right)	1.0	4.0	5.6	0.9	2.1	1.5	2.2	2.3	2.2	2.2	2.2	0.5	2.2	2.1	2.2	2.4	1.9	1.9	2.3
Worrier / anxious feelings	1.0	2.0	4.1	0.3	1.0	1.8	1.3	1.5	1.2	1.2	1.3	2.0	1.7	1.4	1.2	2.0	1.4	1.1	1.3
Falls in the last year	1.0	1.4	1.7	-1.0	-1.2	-0.8	-1.3	-1.3	-1.3	-1.3	-1.3	-1.2	-1.2	-1.3	-1.3	-0.8	-0.9	-1.3	-1.3
Pulse rate	1.0	1.7	3.0	0.3	1.4	0.4	1.5	1.5	1.6	1.5	1.4	0.2	1.6	1.7	1.5	0.4	1.0	1.7	1.4
Mouth/teeth dental problems: Dentures	1.0	1.6	2.2	0.6	1.4	1.3	1.4	1.5	1.3	1.4	1.5	1.1	1.3	1.1	1.4	1.4	0.8	1.1	1.4
Pulse rate, automated reading	1.0	3.3	5.1	1.5	2.1	1.7	1.9	1.9	2.0	2.0	1.9	1.0	2.2	2.2	2.0	0.8	1.4	2.1	1.9
Average weekly red wine intake	1.0	1.4	2.2	-0.3	-1.5	-0.4	-1.4	-1.4	-1.4	-1.4	-1.4	-0.8	-1.3	-1.3	-1.3	-1.0	-1.2	-1.1	-1.3
Guilty feelings	1.0	1.5	2.5	0.8	1.1	1.5	1.1	1.2	1.1	1.1	1.1	1.2	1.4	1.2	1.2	1.6	1.4	1.0	1.2
Current tobacco smoking	0.9	1.4	2.1	0.6	1.3	1.4	1.1	1.2	1.1	1.1	1.1	1.2	1.5	1.3	1.1	1.4	1.1	1.0	1.2
High blood pressure	0.9	2.4	6.2	-0.9	-1.6	-1.5	-1.5	-1.4	-1.6	-1.6	-1.5	-2.5	-1.4	-1.6	-1.6	-1.0	-1.2	-1.7	-1.5
Trunk fat mass	0.9	3.7	7.5	1.4	2.0	1.6	2.0	2.1	2.0	2.0	2.0	0.2	2.0	1.9	2.0	2.7	1.9	1.7	2.0
Prospective memory result	0.9	1.1	2.2	-0.6	-1.0	-1.1	-1.1	-1.1	-1.1	-1.0	-1.0	0.5	-1.2	-1.2	-1.0	-1.5	-1.1	-0.9	-1.0
Blood clot in the leg (DVT)	0.9	1.1	2.0	1.1	1.4	1.3	1.1	1.1	1.1	1.2	1.1	-0.9	1.0	1.0	1.1	0.7	0.8	0.9	1.1
High blood pressure (siblings)	0.9	1.2	1.8	0.1	-1.3	-0.4	-1.3	-1.2	-1.3	-1.3	-1.3	-1.0	-1.2	-1.2	-1.3	-0.5	-0.7	-1.3	-1.3
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.8	-1.7	-0.8	-0.8	-0.9	-0.9	-1.0	-1.0	-0.9	-0.6	-1.0	-1.1	-0.9	-0.8	-1.2	-1.1	-0.9
Arm fat percentage (left)	0.9	3.5	5.3	1.2	2.0	1.5	2.0	2.1	2.0	2.0	2.1	0.3	2.0	1.9	2.1	2.3	1.8	1.7	2.1
Loneliness, isolation	0.9	1.3	2.8	0.6	1.2	0.6	1.2	1.3	1.2	1.3	1.3	-0.5	1.3	1.1	1.2	1.0	1.7	1.0	1.2
Depressed Affect (Nagel 2018)	0.8	1.6	3.9	-0.2	1.4	1.0	1.2	1.4	1.2	1.2	1.3	0.8	1.5	1.2	1.2	1.6	2.0	1.0	1.2
Smoking Status	0.8	1.9	4.1	-0.1	1.4	1.4	1.3	1.4	1.3	1.3	1.3	1.8	1.5	1.3	1.3	2.0	1.3	1.1	1.3
Vitamin and mineral supplements	0.8	1.1	2.6	-0.3	-0.9	-0.7	-1.1	-1.1	-1.1	-1.1	-1.1	-0.4	-1.2	-1.2	-1.1	-0.9	-1.6	-1.3	-1.1
Hair/balding pattern: Pattern 2	0.8	1.1	2.3	0.3	1.1	-0.2	1.1	1.1	1.1	1.1	1.1	0.9	1.0	1.2	1.1	0.8	1.5	1.1	1.1
Father’s age at death	0.8	1.1	1.9	-0.7	-0.8	-0.9	-1.0	-1.2	-1.0	-0.9	-1.0	-0.4	-1.3	-1.1	-1.0	-1.1	-1.4	-1.0	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	2.6	0.4	1.0	0.8	1.2	1.3	1.2	1.2	1.2	0.3	1.2	1.2	1.2	1.6	1.6	1.0	1.2
Hair/balding pattern: Pattern 3	0.8	1.2	3.0	1.7	1.1	0.6	1.2	1.1	1.2	1.2	1.2	-0.5	1.0	1.0	1.1	0.7	0.7	1.2	1.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.3	0.6	1.3	0.5	1.2	1.1	1.2	1.3	1.2	1.3	1.1	1.3	1.3	0.8	1.5	1.2	1.2
Body fat percentage	0.8	3.3	6.8	1.1	1.8	1.3	1.9	2.0	1.9	1.9	2.0	0.4	1.9	1.8	2.0	2.6	1.8	1.6	2.0
Medication: Blood pressure	0.8	1.5	1.9	-0.5	-1.3	-1.0	-1.3	-1.2	-1.3	-1.3	-1.2	-1.4	-1.2	-1.4	-1.3	-0.8	-1.4	-1.3	-1.3
Arm fat mass (left)	0.8	3.2	4.7	1.4	1.9	1.5	1.9	2.0	1.9	1.9	1.9	-0.2	1.9	1.9	1.9	2.2	1.7	1.6	1.9
Financial situation satisfaction	0.8	1.0	3.5	-1.2	-1.1	-1.9	-0.9	-1.0	-0.9	-0.9	-1.0	-0.6	-1.0	-0.9	-1.0	-0.8	-0.6	-0.9	-0.9
Supplements: Calcium	0.8	0.9	3.5	0.2	0.6	0.9	0.9	0.9	0.9	0.9	0.9	1.9	1.0	0.9	1.0	0.8	0.4	0.9	1.0
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.8	1.0	1.3	1.4	1.1	1.0	1.1	1.1	1.1	-0.9	0.9	0.9	1.1	0.8	0.8	0.9	1.0
Intelligence (Savage-Jansen 2018)	0.7	2.1	4.2	2.0	1.3	1.5	1.4	1.5	1.3	1.3	1.4	0.4	1.6	1.4	1.4	1.9	1.5	1.4	1.4
Major Depression (MDD)	0.7	0.8	2.1	-0.1	1.0	0.3	1.0	1.0	1.0	1.0	1.0	0.1	1.0	1.0	0.9	0.8	1.5	1.1	0.8
Blood White Count	0.7	5.4	6.9	2.2	2.6	1.2	2.5	2.5	2.5	2.6	2.5	0.9	2.5	2.5	2.5	1.6	2.1	2.6	2.6
Respiratory disease	0.7	1.6	2.9	0.3	1.0	1.2	1.2	1.3	1.2	1.2	1.2	1.7	1.2	1.3	1.1	1.7	1.3	1.3	1.2
Arm fat mass (right)	0.7	3.0	4.8	1.1	1.8	1.4	1.8	1.9	1.8	1.8	1.9	-0.1	1.9	1.8	1.9	2.2	1.7	1.5	1.9
Age at last live birth	0.7	1.0	1.5	0.6	1.0	1.1	1.1	1.1	1.1	1.0	1.1	0.4	1.2	1.2	1.0	0.9	0.9	0.9	1.1
Family relationship satisfaction	0.7	0.9	1.3	0.8	1.0	0.6	1.0	0.9	1.0	1.0	1.0	1.1	0.9	0.9	1.1	0.9	1.1	0.8	1.1
Mood swings	0.7	1.2	2.6	0.5	1.1	0.9	1.1	1.2	1.1	1.1	1.1	0.8	1.3	1.1	1.1	1.3	1.6	1.0	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.8	0.1	-0.7	-0.3	-0.8	-0.9	-0.7	-0.7	-0.8	-1.7	-0.8	-0.6	-0.8	-1.3	-0.9	-0.6	-0.8
Depression (Nagel 2018)	0.6	0.9	2.3	-0.4	1.1	1.5	0.8	0.9	0.8	0.8	0.8	0.7	1.1	0.9	0.8	1.1	1.4	0.7	0.9
Neuroticism (Nagel 2018)	0.6	1.5	2.9	0.0	1.2	1.3	1.1	1.2	1.0	1.0	1.1	1.6	1.4	1.2	1.0	1.7	1.7	0.9	1.1
Fasting Glucose	0.6	0.7	1.7	1.1	1.0	1.3	0.8	0.6	0.8	0.8	0.7	0.0	0.8	0.9	0.8	0.8	1.0	0.8	0.8
HDL Cholesterol	0.6	1.0	1.5	1.2	0.8	1.0	0.8	0.9	0.8	0.8	0.9	1.0	1.1	1.0	0.9	1.2	1.1	0.9	1.0
Primary Biliary Cirrhosis	0.6	0.8	2.8	-0.4	-0.9	-1.7	-0.8	-0.9	-0.8	-0.8	-0.8	-0.5	-1.0	-0.8	-0.8	-1.5	-0.6	-0.7	-0.8
Pack years adult smoking proportion	0.6	1.0	1.7	1.2	0.9	0.5	1.1	1.3	1.0	1.0	1.1	0.1	1.3	1.1	1.0	0.5	1.0	0.9	1.0
Townsend deprivation index at recruitment	0.6	0.8	2.5	-0.9	-1.1	-1.6	-0.8	-0.8	-0.8	-0.8	-0.8	-0.5	-0.7	-0.7	-0.8	-1.3	-0.3	-1.0	-0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.1	-1.1	-0.9	-0.6	-0.9	-0.8	-0.9	-0.9	-0.9	-0.4	-0.8	-0.8	-0.8	-0.8	-0.9	-0.8	-0.8
Neuroticism score	0.6	1.2	3.4	0.2	0.8	0.8	0.9	1.1	0.9	0.8	1.0	1.8	1.3	1.0	0.9	1.8	1.6	0.6	1.0
Weight	0.6	2.8	4.5	1.5	1.9	1.9	1.7	1.7	1.7	1.6	1.7	-0.6	1.8	1.7	1.7	2.1	1.5	1.4	1.7
Impedance of arm (left)	0.6	2.7	9.1	1.4	1.3	1.2	1.5	1.6	1.5	1.6	1.6	3.0	1.4	1.4	1.5	2.2	1.2	1.6	1.6
Birth weight of first child	0.6	1.0	1.5	-1.1	0.9	-0.4	1.1	1.1	1.1	1.2	1.1	1.2	0.7	0.9	1.0	0.8	1.1	1.1	1.0
Medication: Amlodipine	0.6	0.9	2.2	0.4	-0.9	-1.1	-0.9	-0.9	-0.9	-0.9	-0.9	-1.5	-0.9	-1.0	-1.0	-0.5	-0.8	-1.0	-1.0
Health satisfaction	0.6	0.8	1.4	0.6	0.6	0.4	1.0	1.0	1.0	1.0	1.0	-0.2	1.0	1.0	1.1	1.0	1.2	0.8	1.1
Whole body fat mass	0.6	2.6	5.4	1.2	1.7	1.5	1.7	1.7	1.6	1.6	1.7	-0.1	1.7	1.6	1.7	2.3	1.6	1.3	1.7
Illnesses of father: Heart disease	0.6	0.8	3.8	0.7	0.6	0.7	0.7	0.7	0.7	0.6	0.6	1.9	0.9	0.9	0.6	1.4	0.6	0.8	0.5
Vascular/heart problems diagnosed by doctor	0.6	1.6	4.7	0.7	1.3	1.3	1.2	1.1	1.3	1.3	1.2	2.2	1.0	1.3	1.3	0.7	1.0	1.4	1.2
Alzheimer’s Disease (in father)	0.5	0.5	0.9	0.5	0.7	0.8	0.8	0.8	0.7	0.7	0.8	0.1	0.8	0.7	0.8	0.5	0.9	0.7	0.8
Reaction Time	0.5	0.9	5.1	-0.3	0.6	0.5	0.8	0.9	0.8	0.8	0.8	2.3	0.8	0.7	0.8	1.2	0.7	0.9	0.9
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.2	-1.1	-0.7	-1.1	-0.7	-0.7	-0.7	-0.6	-0.6	-0.8	-0.9	-0.8	-0.6	-0.7	0.2	-0.7	-0.6
Lung FVC	0.5	2.7	4.4	-1.3	-1.3	-1.3	-1.7	-1.7	-1.7	-1.6	-1.7	-2.1	-1.7	-1.7	-1.7	-1.6	-1.7	-1.7	-1.7
Number of treatments/medications taken	0.5	0.8	1.6	0.9	0.6	0.7	1.0	1.1	1.0	1.0	1.0	-0.1	1.0	0.8	1.0	1.2	0.7	0.9	1.1
Diabetes (mother)	0.5	0.7	1.8	-1.0	-0.9	-1.3	-0.7	-0.8	-0.7	-0.7	-0.7	-0.7	-0.9	-0.9	-0.7	-0.5	-0.5	-0.7	-0.8
Age when periods started (menarche)	0.5	1.2	3.7	-1.9	-1.1	-1.6	-0.9	-0.9	-0.9	-1.0	-1.0	0.0	-0.8	-0.6	-1.0	-1.7	-0.5	-0.8	-1.0
Nervous feelings	0.5	1.0	5.0	-2.2	-1.2	-1.2	-0.9	-0.7	-0.9	-1.0	-0.9	-0.0	-0.7	-0.8	-0.9	-0.5	-0.2	-1.1	-0.9
Heart attack	0.5	0.7	1.0	0.7	0.8	0.9	0.9	0.8	0.9	0.9	0.9	0.8	0.8	0.8	0.9	0.8	0.2	0.6	1.0
Number of live births	0.5	0.6	1.9	0.5	0.8	0.6	0.8	0.8	0.8	0.8	0.8	0.3	0.8	0.8	0.8	1.4	0.1	0.9	0.9
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.2	1.0	1.5	1.1	0.9	0.9	1.0	1.0	0.9	-1.5	0.9	1.0	0.9	0.5	0.7	1.1	0.9
Pulse wave reflection index	0.5	0.6	2.0	-0.3	-0.6	-1.4	-0.7	-0.7	-0.7	-0.6	-0.6	-1.2	-0.9	-0.9	-0.7	-0.5	-0.0	-0.8	-0.7
Exposure to tobacco smoke outside home	0.5	0.7	1.0	-0.2	0.5	-0.6	0.9	0.9	0.9	1.0	1.0	1.0	0.7	0.7	0.9	0.8	0.6	1.0	1.0
Pulse wave peak to peak time	0.5	0.5	2.6	1.3	0.7	1.6	0.4	0.4	0.4	0.4	0.4	1.0	0.7	0.6	0.4	0.7	-0.2	0.5	0.5
Medication for pain relief, constipation, heartburn	0.5	0.9	1.3	-0.7	-0.8	-0.7	-1.0	-1.1	-1.0	-1.0	-1.0	-0.5	-1.1	-1.1	-1.1	-0.9	-0.9	-1.1	-1.1
Migraine (self-reported)	0.5	0.6	3.8	0.1	0.6	1.3	0.6	0.6	0.6	0.6	0.6	2.0	0.6	0.6	0.6	0.8	0.5	0.5	0.6
Medication: Blood pressure	0.5	0.9	1.2	0.5	1.0	0.7	1.1	1.1	1.0	1.1	1.1	-0.2	1.0	0.8	1.1	1.1	0.7	0.9	1.1
Unable to work because of sickness or disability	0.5	0.6	1.2	0.9	0.7	1.1	0.8	0.9	0.7	0.7	0.8	0.1	1.0	0.7	0.8	1.1	0.7	0.6	0.8
Heart attack/myocardial infarction (self-reported)	0.5	0.6	0.9	0.8	0.8	0.9	0.8	0.8	0.8	0.9	0.8	0.8	0.7	0.7	0.9	0.7	0.1	0.6	0.9
Mean Putamen Volume	0.4	0.4	1.4	1.0	-0.2	1.0	-0.5	-0.4	-0.5	-0.5	-0.5	-0.9	-0.2	-0.4	-0.5	-0.7	-1.2	-0.4	-0.5
Rheumatoid Arthritis	0.4	0.6	1.0	-0.6	-1.0	-0.4	-0.8	-0.8	-0.8	-0.9	-0.9	0.7	-0.7	-0.6	-0.9	-0.9	-0.5	-0.7	-0.8
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.6	0.2	0.6	1.3	0.6	0.7	0.6	0.6	0.6	-0.2	0.8	0.7	0.6	0.9	1.0	0.4	0.7
Systolic blood pressure, automated reading	0.4	1.3	1.7	-0.9	-1.2	-0.9	-1.2	-1.1	-1.2	-1.2	-1.2	-1.0	-1.3	-1.2	-1.2	-1.0	-1.0	-1.3	-1.2
Leg fat-free mass (left)	0.4	2.0	3.9	1.8	1.6	2.0	1.3	1.3	1.4	1.3	1.3	-0.9	1.5	1.5	1.3	1.5	1.1	1.2	1.3
Medication: Levothyroxine sodium	0.4	0.7	1.1	0.3	-1.1	-0.5	-0.9	-1.0	-0.9	-0.9	-0.9	0.7	-1.0	-0.8	-0.9	0.2	-0.7	-0.6	-1.0
Had other major operations	0.4	0.5	3.4	1.9	0.1	1.5	0.2	0.4	0.2	0.1	0.2	-0.4	0.4	0.2	0.1	1.2	-0.1	0.1	0.1
Hip circumference	0.4	1.8	3.1	1.3	1.5	1.5	1.3	1.4	1.3	1.3	1.3	-0.5	1.5	1.4	1.3	1.7	1.1	1.1	1.3
Noisy workplace	0.4	0.5	2.0	-0.8	-0.7	-1.4	-0.4	-0.5	-0.4	-0.4	-0.4	-1.0	-0.6	-0.4	-0.4	-1.1	0.0	-0.4	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.3	-1.0	-0.7	-1.5	-0.5	-0.4	-0.5	-0.5	-0.4	0.3	-0.6	-0.6	-0.5	0.0	0.4	-0.7	-0.5
Depression (self-reported)	0.4	0.5	0.8	0.1	0.7	0.2	0.7	0.7	0.7	0.8	0.7	-0.3	0.7	0.7	0.8	0.8	0.9	0.5	0.8
Illnesses of mother	0.4	0.4	1.3	-0.3	-0.5	-0.6	-0.5	-0.6	-0.5	-0.5	-0.5	-0.9	-0.7	-0.7	-0.6	-0.8	-1.1	-0.5	-0.6
Pulse wave Arterial Stiffness index	0.4	0.5	2.1	-1.2	-0.7	-1.4	-0.4	-0.4	-0.4	-0.4	-0.4	-1.1	-0.6	-0.6	-0.4	-0.5	0.2	-0.5	-0.5
Glaucoma (self-reported)	0.4	0.5	1.2	1.1	0.5	0.8	0.6	0.6	0.5	0.5	0.6	0.9	0.7	0.5	0.6	0.8	1.0	0.5	0.7
Wheeze or whistling in the chest in last year	0.4	0.7	1.5	0.9	0.8	-0.2	0.9	0.9	0.9	0.9	0.9	-0.9	0.8	0.8	0.8	1.2	0.9	0.7	0.8
Mean time to correctly identify matches	0.4	0.7	5.2	-0.7	0.3	0.3	0.5	0.7	0.5	0.5	0.6	2.3	0.5	0.4	0.5	1.3	0.6	0.4	0.6
Heart disease (mother)	0.4	0.4	3.3	-1.8	-0.6	0.2	-0.5	-0.4	-0.6	-0.6	-0.5	-0.2	-0.3	-0.6	-0.5	0.8	-0.5	-0.5	-0.5
Leg fat-free mass (right)	0.4	2.1	3.8	1.9	1.6	1.9	1.4	1.4	1.4	1.3	1.4	-0.7	1.5	1.5	1.4	1.6	1.2	1.3	1.3
Long-standing illness, disability or infirmity	0.4	0.7	1.0	-0.0	-0.8	-0.0	-0.9	-0.9	-0.9	-1.0	-0.9	-0.7	-0.9	-0.9	-1.0	0.4	-0.8	-1.0	-1.0
Mineral and other dietary supplements	0.4	0.6	1.8	-0.6	0.6	0.5	0.7	0.7	0.7	0.7	0.7	1.4	0.8	0.8	0.7	0.8	0.7	0.6	0.7
Leg predicted mass (right)	0.4	2.2	4.0	1.8	1.7	2.0	1.4	1.4	1.5	1.4	1.4	-0.7	1.6	1.6	1.4	1.7	1.2	1.3	1.4
Miserableness	0.4	0.7	1.8	0.4	0.7	0.2	0.8	1.0	0.8	0.7	0.8	0.8	1.2	0.9	0.8	0.9	1.3	0.6	0.9
Irritability	0.4	0.7	1.7	0.9	0.7	0.5	0.7	0.8	0.7	0.6	0.7	0.8	0.9	0.8	0.7	1.3	1.1	0.6	0.7
Pack years of smoking	0.4	0.6	1.2	1.0	0.8	0.4	0.9	1.1	0.8	0.8	0.9	-0.2	1.0	0.8	0.7	0.4	0.9	0.7	0.8
Bipolar Disorder (2018)	0.3	0.5	1.0	0.0	-0.5	-0.2	-0.7	-0.8	-0.7	-0.7	-0.7	-1.0	-0.6	-0.7	-0.7	-0.7	-0.8	-0.7	-0.7
Irritable Bowel Disease (IBD)	0.3	0.8	1.3	1.1	0.9	1.0	0.9	0.9	0.9	1.0	1.0	0.6	0.8	0.8	1.0	0.8	0.4	0.9	1.0
Ulcerative Colitis (UC)	0.3	0.6	0.9	0.5	0.8	0.6	0.9	0.8	0.9	0.9	0.9	0.3	0.7	0.7	0.9	0.5	0.4	0.8	0.9
Body Mass Index (BMI) (2010)	0.3	0.4	2.3	0.6	0.3	1.5	0.3	0.4	0.3	0.4	0.4	1.2	0.5	0.4	0.4	0.2	0.4	0.4	0.5
HbA1C	0.3	0.4	0.8	0.1	0.8	-0.1	0.9	0.0	0.9	0.9	0.5	0.2	0.3	0.7	0.9	-0.1	0.4	0.7	0.8
LDL Cholesterol	0.3	0.5	0.8	-0.9	-0.7	-0.6	-0.8	-0.7	-0.7	-0.7	-0.7	-0.2	-0.7	-0.7	-0.7	-0.1	-0.6	-0.8	-0.7
Lupus	0.3	0.4	1.1	1.1	0.8	0.6	0.6	0.6	0.7	0.6	0.6	0.8	0.7	0.8	0.6	0.6	0.1	0.4	0.6
Blood Platelet Count	0.3	3.3	4.7	1.9	1.8	0.1	2.0	2.1	2.0	2.0	2.0	-0.6	2.0	2.0	1.9	1.3	1.7	2.2	1.9
BMI	0.3	1.6	2.2	1.5	1.4	0.7	1.3	1.3	1.3	1.3	1.3	-0.7	1.3	1.4	1.4	1.2	1.4	1.1	1.3
Waist Hip Ratio (WHR)	0.3	1.5	2.7	-0.4	-1.6	-1.4	-1.3	-1.2	-1.3	-1.3	-1.2	-0.1	-1.4	-1.6	-1.3	-0.4	-1.4	-1.5	-1.3
Cardiovascular Disease	0.3	0.9	3.6	-0.2	-1.0	-1.6	-0.7	-0.8	-0.7	-0.7	-0.7	-1.9	-0.7	-0.7	-0.6	-0.8	-0.9	-0.7	-0.7
Hand grip strength (left)	0.3	0.8	2.5	-1.1	-0.7	-1.4	-0.7	-0.8	-0.6	-0.6	-0.7	-0.5	-0.9	-0.7	-0.6	-1.6	-1.0	-0.6	-0.7
Severe depression (siblings)	0.3	0.4	1.8	0.8	0.4	1.3	0.5	0.6	0.5	0.5	0.5	-0.2	0.6	0.6	0.5	0.3	0.5	0.5	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.3	0.2	0.4	0.9	0.4	0.5	0.3	0.3	0.4	0.9	0.7	0.5	0.4	1.0	1.1	0.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.4	0.2	0.8	1.2	0.8	0.8	0.8	0.8	0.8	0.8	0.8	0.9	0.8	0.7	0.9	0.9	0.7
Body mass index (BMI)	0.3	1.1	1.5	0.5	1.2	0.7	1.1	1.2	1.1	1.1	1.2	-1.1	1.1	1.0	1.2	1.2	1.0	0.8	1.2
Leg predicted mass (left)	0.3	1.7	3.3	1.7	1.5	1.8	1.2	1.2	1.3	1.2	1.2	-1.0	1.3	1.3	1.2	1.4	1.0	1.1	1.2
Forced vital capacity (FVC)	0.3	1.2	3.2	0.8	-0.9	-0.2	-1.1	-1.2	-1.0	-0.9	-1.1	-1.8	-1.1	-1.0	-1.0	-1.3	-1.4	-1.0	-1.1
Fluid intelligence score	0.3	0.5	1.4	1.2	0.8	1.1	0.6	0.6	0.6	0.6	0.6	0.2	0.7	0.6	0.6	1.2	0.2	0.7	0.7
Number of children fathered	0.3	0.3	1.8	0.2	-0.3	-0.2	-0.5	-0.4	-0.5	-0.5	-0.5	-1.3	-0.2	-0.2	-0.6	-0.7	-0.4	-0.2	-0.5
Age at first live birth	0.3	0.5	1.5	1.2	0.8	0.9	0.6	0.7	0.6	0.6	0.6	-0.4	0.7	0.7	0.7	0.8	0.5	0.5	0.7
Leg fat mass (right)	0.3	1.3	2.4	0.9	1.2	1.0	1.2	1.3	1.2	1.2	1.3	-0.7	1.2	1.1	1.3	1.6	1.1	0.9	1.3
Number of full sisters	0.3	0.4	0.7	-0.1	0.6	0.5	0.7	0.6	0.7	0.7	0.7	0.3	0.6	0.7	0.7	0.2	0.6	0.8	0.6
Medication: Aspirin	0.3	0.3	1.1	0.0	0.3	1.1	0.4	0.6	0.4	0.4	0.5	0.7	0.8	0.5	0.5	0.8	0.7	0.4	0.5
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.4	-0.8	-0.4	-0.1	-0.5	-0.5	-0.5	-0.5	-0.5	-0.3	-0.4	-0.5	-0.5	-1.2	-0.9	-0.5	-0.5
Qualifications: nursing, teaching	0.3	0.5	0.8	-0.8	-0.9	-0.8	-0.7	-0.7	-0.7	-0.7	-0.7	-0.5	-0.8	-0.7	-0.6	-0.7	-0.7	-0.7	-0.7
Ever taken oral contraceptive pill	0.3	0.4	1.2	0.4	0.5	0.0	0.6	0.6	0.6	0.6	0.6	1.1	0.4	0.4	0.6	1.0	0.6	0.7	0.6
Leg fat percentage (left)	0.3	0.9	2.0	0.4	0.9	0.4	1.1	1.1	1.0	1.0	1.1	-0.1	1.0	0.9	1.1	1.4	1.1	0.7	1.1
Alcohol drinker status: Previous	0.3	0.3	0.6	-0.6	-0.7	-0.8	-0.5	-0.4	-0.5	-0.5	-0.5	-0.3	-0.4	-0.5	-0.5	-0.5	-0.8	-0.6	-0.5
Leg fat mass (left)	0.3	1.4	2.8	0.9	1.2	1.0	1.2	1.3	1.2	1.2	1.2	-0.5	1.2	1.1	1.2	1.7	1.2	0.9	1.3
Bipolar Disorder or Schizophrenia	0.2	0.4	1.2	-0.1	-0.5	-1.1	-0.6	-0.6	-0.5	-0.6	-0.6	-0.3	-0.7	-0.6	-0.6	-0.8	-0.4	-0.6	-0.6
Crohns Disease (2017)	0.2	0.4	1.6	1.3	0.6	1.1	0.6	0.5	0.6	0.6	0.6	0.1	0.5	0.5	0.6	0.6	0.2	0.5	0.6
Coronary Artery Disease (CAD)	0.2	0.3	1.0	0.9	0.5	1.0	0.4	0.3	0.5	0.5	0.4	0.2	0.2	0.4	0.5	0.5	0.4	0.3	0.5
Crohns Disease (2012)	0.2	0.4	1.6	1.3	0.4	1.3	0.4	0.5	0.4	0.4	0.4	0.3	0.6	0.5	0.5	0.2	0.3	0.4	0.5
Sensitivity / hurt feelings	0.2	0.3	3.1	-0.4	0.3	0.5	0.1	0.2	0.1	0.0	0.1	1.8	0.4	0.4	0.1	0.2	0.6	0.2	0.2
Angina	0.2	0.2	1.2	1.1	-0.4	0.5	-0.3	-0.2	-0.4	-0.4	-0.3	-0.2	-0.2	-0.4	-0.3	0.4	-0.4	-0.5	-0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.6	0.5	-0.5	0.8	-0.5	-0.4	-0.6	-0.6	-0.5	0.4	-0.4	-0.6	-0.5	0.5	-0.5	-0.6	-0.4
Past tobacco smoking	0.2	0.3	2.4	0.2	-0.4	-0.2	-0.3	-0.3	-0.2	-0.2	-0.3	-1.2	-0.2	0.0	-0.2	-1.6	-0.5	-0.2	-0.2
Had menopause	0.2	0.3	1.8	-1.3	0.1	0.1	-0.1	0.1	-0.1	-0.1	-0.0	1.0	0.0	-0.3	-0.1	1.1	0.2	-0.3	-0.1
Alcohol intake versus 10 years previously	0.2	0.3	1.0	-0.8	-0.8	-1.0	-0.5	-0.5	-0.5	-0.5	-0.6	0.2	-0.5	-0.4	-0.6	-0.4	0.2	-0.6	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.4	0.7	-0.5	-0.2	-0.6	-0.8	-0.6	-0.5	-0.7	-1.9	-0.7	-0.6	-0.6	-1.1	-0.9	-0.6	-0.7
Standing height	0.2	1.6	5.3	1.9	1.3	2.3	1.0	1.1	1.1	1.0	1.0	0.5	1.2	1.1	1.0	1.8	0.9	1.0	1.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.2	0.5	0.7	0.7	0.5	0.5	0.6	0.5	0.5	-0.1	0.7	0.6	0.5	1.1	0.6	0.9	0.5
Leg fat percentage (right)	0.2	0.8	1.5	0.2	0.9	0.3	1.0	1.0	0.9	1.0	1.0	-0.4	0.9	0.8	1.0	1.2	1.0	0.6	1.0
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	0.8	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.8	0.5	0.5	0.5	0.4	0.5	0.4	0.5
Emphysema/chronic bronchitis	0.2	0.2	1.3	0.5	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.2	0.4	0.2	0.4	1.1	0.2	0.3	0.4
Angina (self-reported)	0.2	0.3	1.0	1.0	-0.6	0.4	-0.5	-0.4	-0.5	-0.5	-0.4	-0.4	-0.4	-0.5	-0.4	0.2	-0.6	-0.6	-0.4
Alcohol intake frequency.	0.2	0.5	0.8	0.1	0.7	0.5	0.8	0.9	0.8	0.8	0.8	-0.1	0.9	0.8	0.8	0.6	0.7	0.8	0.8
Comparative height size at age 10	0.2	1.2	6.1	2.5	1.0	1.4	0.8	0.8	0.8	0.7	0.8	-0.1	1.1	1.0	0.8	1.1	1.0	0.8	0.8
Suffer from ‘nerves’	0.2	0.4	1.9	-0.0	0.2	0.6	0.5	0.7	0.5	0.5	0.5	0.2	0.7	0.5	0.5	1.4	0.8	0.2	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.8	-0.1	-0.3	-0.6	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.5	-0.4	-0.4	-0.8	-0.9	-0.2	-0.3
Supplements: Vitamin C	0.2	0.2	1.1	-1.1	-0.4	-0.7	-0.4	-0.3	-0.4	-0.4	-0.4	0.5	-0.2	-0.3	-0.4	0.2	0.8	-0.3	-0.3
Medication: Aspirin	0.2	0.2	0.8	0.1	0.2	0.9	0.3	0.4	0.3	0.2	0.3	0.6	0.6	0.4	0.4	0.6	0.5	0.2	0.4
Illnesses of father: None of the above (group 1)	0.2	0.3	1.8	-1.1	-0.3	-0.8	-0.1	-0.1	-0.1	-0.0	-0.1	-1.3	-0.3	-0.3	-0.1	-0.7	-0.1	-0.2	-0.1
Wears glasses or contact lenses	0.2	0.3	1.0	-0.7	0.5	1.0	0.3	0.5	0.3	0.3	0.4	0.1	0.7	0.3	0.3	1.0	0.4	0.0	0.3
Mother’s age at death	0.2	0.2	0.5	-0.7	-0.1	0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.2	-0.4	-0.6	-0.4	0.1	-0.4	-0.7	-0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.6	0.2	-0.4	-0.6	-0.4	-0.3	-0.4	-0.4	-0.4	-0.3	-0.4	-0.6	-0.5	0.3	-0.4	-0.7	-0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.2	1.0	-0.1	-0.2	-0.4	-0.4	-0.4	-0.4	-0.4	-1.1	-0.4	-0.4	-0.4	-0.2	-0.0	-0.3	-0.4
Alcohol drinker status: Never	0.2	0.2	2.0	0.8	0.1	0.8	0.1	0.1	0.1	0.1	0.1	-1.4	0.0	-0.0	0.1	0.1	-0.6	0.1	0.2
Basal metabolic rate	0.2	1.0	2.2	1.3	1.1	1.5	0.9	0.9	0.9	0.9	0.9	-1.3	1.1	1.0	0.9	1.0	0.7	0.8	0.9
Risk taking	0.2	0.2	1.5	1.2	0.4	0.1	0.5	0.4	0.5	0.5	0.5	-0.3	0.2	0.4	0.4	0.4	0.3	0.6	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.3	-1.1	-0.3	-0.7	-0.2	-0.2	-0.2	-0.2	-0.2	0.9	-0.4	-0.2	-0.2	-0.1	0.2	-0.2	-0.1
Fractured/broken bones in last 5 years	0.2	0.3	1.9	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-1.4	-0.3	-0.4	-0.4	-0.5	-0.4	-0.4	-0.5
Diastolic blood pressure, automated reading	0.2	0.6	1.6	0.4	1.0	0.1	0.8	0.8	0.8	0.8	0.8	-0.1	0.7	0.7	0.8	0.8	1.2	0.6	0.7
Commuting to job workplace: Cycle	0.2	0.3	1.3	0.5	-0.2	-0.9	-0.3	-0.4	-0.2	-0.2	-0.3	-0.4	-0.5	-0.2	-0.3	-1.1	-0.8	-0.1	-0.4
Myopia	0.2	0.3	1.6	1.3	0.3	1.0	0.1	0.2	0.0	-0.0	0.1	0.4	0.4	0.2	-0.0	1.0	-0.0	0.1	0.0
Cholesterol lowering medication	0.2	0.2	0.5	-0.5	0.2	-0.1	0.5	0.6	0.5	0.5	0.6	0.7	0.5	0.3	0.6	0.4	0.1	0.3	0.6
Pain experienced in last month	0.2	0.4	0.7	0.3	0.9	0.8	0.7	0.6	0.7	0.8	0.7	-0.3	0.4	0.5	0.7	0.1	0.1	0.7	0.7
Heart disease (siblings)	0.2	0.3	1.2	-0.2	0.2	0.4	0.4	0.6	0.3	0.3	0.4	0.7	0.7	0.6	0.3	0.3	1.1	0.4	0.4
Schizophrenia (2018)	0.1	0.2	1.5	-0.3	-0.2	-1.2	-0.1	-0.2	-0.1	-0.1	-0.1	0.4	-0.4	-0.2	-0.2	-0.4	0.2	-0.2	-0.3
Worry (Nagel 2018)	0.1	0.2	0.8	-0.9	-0.1	0.8	0.1	0.2	0.0	0.1	0.1	0.8	0.3	0.2	0.1	0.8	0.5	-0.1	0.2
Age at First Birth	0.1	0.1	0.3	0.1	0.3	0.6	0.4	0.4	0.4	0.4	0.4	0.0	0.3	0.4	0.4	0.5	0.0	0.5	0.4
Schizophrenia (2014)	0.1	0.3	0.6	0.4	0.6	-0.1	0.6	0.5	0.7	0.7	0.6	0.6	0.4	0.6	0.7	0.2	0.8	0.6	0.6
Ulcerative Colitis	0.1	0.1	0.5	-0.7	-0.1	-0.4	-0.0	-0.1	-0.1	-0.0	-0.0	0.6	-0.2	-0.2	0.0	-0.2	-0.3	-0.1	0.0
Hypothyroidism (self reported)	0.1	0.2	0.8	0.7	0.1	0.7	0.1	0.1	0.1	0.1	0.1	0.9	0.1	0.1	0.2	0.8	0.1	0.3	0.1
Lung FEV1/FVC ratio	0.1	0.3	2.4	-1.6	0.1	-1.1	-0.0	-0.2	0.1	0.1	-0.0	0.4	-0.3	-0.1	0.1	-0.5	0.2	-0.1	0.0
Tanning	0.1	0.8	2.6	1.6	-0.5	0.3	-0.9	-0.8	-0.9	-0.9	-0.9	-1.2	-0.7	-0.8	-0.9	-0.6	-1.4	-0.7	-0.9
Average weekly spirits intake	0.1	0.1	0.5	0.5	-0.3	-0.5	-0.2	-0.3	-0.2	-0.2	-0.2	-0.7	-0.3	-0.4	-0.2	-0.5	-0.5	-0.4	-0.1
Hearing difficulty/problems: Yes	0.1	0.2	1.1	-0.1	0.2	-0.9	0.3	0.3	0.3	0.3	0.3	-0.3	0.2	0.3	0.3	0.3	1.0	0.2	0.3
Relative age of first facial hair	0.1	0.2	0.5	-0.1	0.5	0.7	0.4	0.4	0.4	0.4	0.4	0.4	0.4	0.3	0.4	0.6	-0.1	0.6	0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.7	0.2	0.2	-0.1	0.2	0.2	0.1	0.1	0.2	-0.8	0.3	0.2	0.1	0.3	0.2	0.1	0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.7	0.3	0.2	0.8	-0.1	-0.1	-0.1	-0.1	-0.1	-0.6	-0.1	-0.3	-0.1	0.7	0.2	-0.3	-0.1
Medication: Co-codamol	0.1	0.1	1.1	-0.1	-0.1	-0.5	0.0	0.1	-0.0	0.0	0.0	-1.0	-0.0	-0.1	-0.1	0.0	0.1	-0.2	0.0
Impedance of leg (right)	0.1	0.5	2.3	-1.0	-0.8	-1.5	-0.5	-0.6	-0.5	-0.4	-0.5	1.0	-0.8	-0.8	-0.5	-0.3	-0.6	-0.5	-0.4
Relative age voice broke	0.1	0.1	0.6	-0.6	0.2	-0.5	0.1	0.0	0.1	0.0	0.0	0.8	-0.1	0.1	0.0	-0.1	-0.1	0.4	-0.0
Medication: Atenolol	0.1	0.2	0.7	0.9	0.2	0.8	0.0	-0.0	-0.0	-0.0	-0.0	-0.9	0.0	-0.0	-0.1	0.5	-0.6	0.1	-0.1
Sitting height	0.1	0.6	2.0	1.4	0.9	0.9	0.7	0.7	0.7	0.7	0.7	-0.5	0.7	0.7	0.7	1.0	0.6	0.8	0.7
High blood pressure (mother)	0.1	0.1	0.4	-0.6	-0.0	-0.0	-0.2	-0.3	-0.1	-0.1	-0.2	0.6	-0.3	-0.0	-0.2	-0.4	0.4	0.1	-0.2
Impedance of leg (left)	0.1	0.6	2.8	-0.9	-0.9	-1.7	-0.5	-0.6	-0.5	-0.5	-0.5	1.4	-0.8	-0.8	-0.5	-0.2	-0.5	-0.5	-0.4
Waist circumference	0.1	0.5	1.6	1.0	0.7	0.8	0.6	0.7	0.6	0.6	0.7	-1.1	0.7	0.5	0.6	1.3	0.5	0.2	0.6
Number of incorrect matches in round	0.1	0.1	1.0	-0.8	-0.0	-0.4	0.1	0.1	0.1	0.1	0.1	1.0	0.1	0.1	0.1	-0.3	-0.2	0.1	0.1
Pain all over the body in last month	0.1	0.2	1.0	-0.3	-0.2	-0.4	-0.3	-0.3	-0.3	-0.5	-0.4	-1.0	0.0	-0.0	-0.4	-0.1	0.3	-0.3	-0.4
Medication: Simvastatin	0.1	0.1	0.7	-0.8	-0.1	-0.7	0.1	0.1	0.0	0.0	0.1	0.4	0.0	-0.1	0.0	0.3	-0.1	-0.1	0.1
Lung cancer (father)	0.1	0.1	0.7	0.3	-0.2	-0.4	-0.1	-0.2	-0.1	-0.1	-0.1	-0.8	-0.2	-0.1	-0.1	-0.6	0.3	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.5	1.6	0.6	0.9	0.4	0.3	0.5	0.5	0.4	-0.8	0.4	0.5	0.5	-0.0	-0.1	0.6	0.4
Breastfed as a baby	0.1	0.1	0.5	-0.2	0.2	-0.7	0.2	0.1	0.3	0.3	0.2	0.5	-0.2	0.1	0.2	0.1	-0.0	0.3	0.2
Tense / ‘highly strung’	0.1	0.1	0.4	0.0	-0.1	0.5	-0.1	0.0	-0.2	-0.2	-0.2	0.7	0.3	0.1	-0.2	0.5	0.5	-0.1	-0.1
Medication: Paracetamol	0.1	0.1	0.7	-0.8	-0.5	-0.6	-0.2	-0.3	-0.2	-0.1	-0.2	0.4	-0.4	-0.2	-0.2	-0.4	-0.4	-0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.5	0.6	-0.4	-0.0	-0.3	-0.4	-0.3	-0.4	-0.3	1.2	-0.4	-0.3	-0.3	0.8	0.1	-0.1	-0.3
Birth weight	0.1	0.3	0.5	-0.1	0.7	0.7	0.6	0.6	0.6	0.6	0.6	-0.3	0.6	0.5	0.5	0.7	0.1	0.5	0.5
Forced vital capacity (FVC), Best measure	0.1	0.3	2.7	1.6	0.3	0.9	0.1	0.0	0.1	0.2	0.1	-0.8	0.1	0.2	0.1	-0.0	-0.4	0.2	0.1
Arm fat-free mass (right)	0.1	0.3	4.1	0.6	0.1	0.8	-0.2	-0.1	-0.2	-0.2	-0.2	-2.0	0.0	-0.0	-0.2	0.2	-0.1	-0.3	-0.2
Comparative body size at age 10	0.1	0.3	1.3	0.1	-0.4	0.3	-0.5	-0.4	-0.5	-0.4	-0.4	-0.3	-0.4	-0.5	-0.4	-1.0	-1.1	-0.6	-0.5
Worry too long after embarrassment	0.1	0.2	0.6	-0.4	-0.5	-0.8	-0.3	-0.2	-0.3	-0.4	-0.3	0.3	-0.2	-0.3	-0.4	0.3	-0.4	-0.5	-0.3
Qualifications: College or University degree	0.1	0.4	1.2	-0.3	-0.2	-0.1	-0.6	-0.7	-0.5	-0.5	-0.6	-1.1	-0.7	-0.6	-0.6	-0.6	-1.0	-0.4	-0.8
Arm predicted mass (right)	0.1	0.4	5.4	0.4	0.0	0.6	-0.3	-0.3	-0.2	-0.3	-0.3	-2.3	-0.1	-0.1	-0.3	0.0	-0.2	-0.4	-0.3
Overall health rating	0.1	0.2	1.0	0.1	0.0	0.1	0.1	0.3	0.1	0.0	0.1	-0.9	0.3	0.1	0.1	1.0	0.6	-0.3	0.2
Knee pain experienced in last month	0.1	0.1	0.8	-0.5	-0.5	-0.9	-0.1	-0.0	-0.1	-0.2	-0.1	-0.4	-0.0	-0.0	-0.2	0.2	0.3	-0.2	-0.2
Smoking status: Previous	0.1	0.1	1.0	-0.5	-0.1	-0.4	-0.1	-0.0	-0.1	-0.1	-0.0	0.1	-0.3	-0.4	-0.1	1.0	0.1	-0.2	-0.1
Whole body fat-free mass	0.1	0.6	2.3	1.0	0.8	1.3	0.5	0.5	0.6	0.5	0.5	-1.5	0.7	0.7	0.5	0.6	0.4	0.5	0.5
Commuting to job workplace: Walk	0.1	0.2	0.9	-0.5	0.0	-0.9	0.1	0.1	0.1	0.1	0.1	-0.8	-0.1	0.1	0.0	-0.4	0.5	0.3	-0.0
Eye problems/disorders: Cataract	0.1	0.1	0.4	-0.4	-0.2	-0.7	-0.2	-0.2	-0.2	-0.2	-0.2	-0.5	-0.4	-0.3	-0.2	-0.3	-0.1	-0.5	-0.2
Osteoporosis (self-reported)	0.1	0.2	1.0	0.2	-0.5	-0.3	-0.3	-0.4	-0.3	-0.4	-0.4	1.0	-0.3	-0.2	-0.4	-0.2	-0.7	-0.0	-0.3
Osteoarthritis (self-reported)	0.1	0.1	0.5	0.6	-0.1	0.6	-0.1	0.1	-0.2	-0.2	-0.1	-0.4	0.4	0.1	-0.2	0.4	0.7	-0.3	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.8	0.3	-0.1	0.1	-0.2	-0.3	-0.3	-0.2	-0.2	-0.9	-0.4	-0.3	-0.2	-0.7	-0.6	-0.3	-0.3
Whole body water mass	0.1	0.7	2.2	1.1	0.9	1.4	0.7	0.7	0.7	0.6	0.6	-1.5	0.8	0.8	0.6	0.7	0.5	0.6	0.6
Number of self-reported non-cancer illnesses	0.1	0.2	0.6	-0.5	-0.7	-0.4	-0.5	-0.5	-0.6	-0.6	-0.5	-0.4	-0.5	-0.5	-0.6	-0.1	-0.2	-0.5	-0.5
High cholesterol (Self-reported)	0.1	0.2	1.1	-1.1	-0.4	-0.9	-0.1	-0.1	-0.1	-0.1	-0.1	0.5	-0.2	-0.3	-0.1	0.3	-0.3	-0.2	-0.0
Medication: Paracetamol	0.1	0.2	1.9	-1.4	-0.4	-0.6	-0.1	-0.2	-0.1	-0.0	-0.1	0.6	-0.2	-0.1	-0.0	-0.2	-0.2	-0.2	0.1
Medication: Lisinopril	0.1	0.1	0.6	0.5	0.4	0.2	0.2	0.2	0.2	0.2	0.2	-0.8	0.1	0.1	0.2	0.0	-0.0	0.2	0.2
Ever smoked	0.1	0.2	1.0	-0.4	0.0	0.4	-0.2	-0.1	-0.2	-0.2	-0.2	1.0	-0.1	-0.4	-0.2	1.0	0.0	-0.3	-0.2
Arm fat-free mass (left)	0.1	0.3	2.9	0.5	0.5	0.7	0.3	0.3	0.3	0.2	0.3	-1.7	0.4	0.4	0.3	0.4	0.4	0.2	0.2
Number of operations (self-reported)	0.1	0.1	0.6	0.8	0.2	0.6	0.2	0.2	0.2	0.2	0.3	-0.3	0.1	0.1	0.2	0.6	-0.2	0.1	0.2
Average weekly beer plus cider intake	0.1	0.1	0.2	0.2	-0.1	-0.4	0.3	0.3	0.3	0.3	0.3	0.3	0.2	0.2	0.3	0.1	-0.2	0.4	0.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	0.7	-0.3	0.3	0.0	0.1	0.0	-0.0	0.0	0.2	0.2	0.1	-0.0	0.5	0.1	0.0	0.0
Impedance of whole body	0.1	0.6	6.2	0.1	0.1	-0.3	0.5	0.5	0.5	0.5	0.5	2.5	0.4	0.3	0.5	1.1	0.4	0.5	0.6
Arm predicted mass (left)	0.1	0.3	3.2	0.4	0.3	0.6	0.1	0.1	0.1	0.1	0.1	-1.8	0.2	0.2	0.1	0.4	0.2	-0.0	0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.2	1.2	-0.5	0.2	-0.6	0.4	0.4	0.3	0.4	0.4	-1.1	0.1	0.2	0.3	0.7	0.7	0.2	0.3
Heel T-Score	0.0	0.3	1.8	-0.0	-0.3	-0.2	-0.5	-0.4	-0.5	-0.5	-0.5	-1.4	-0.4	-0.4	-0.5	-0.1	0.1	-0.5	-0.6
Height	0.0	0.3	1.4	1.2	0.5	0.5	0.3	0.3	0.3	0.2	0.2	-0.1	0.5	0.4	0.2	0.9	0.6	0.3	0.2
Neuroticism	0.0	0.1	0.2	-0.3	0.1	-0.3	0.1	0.2	0.1	0.1	0.2	0.5	0.1	-0.0	0.1	0.5	0.4	-0.3	0.1
Hair Pigment	0.0	0.6	2.2	-0.7	0.6	0.0	0.7	0.7	0.7	0.7	0.7	0.6	0.8	0.8	0.9	1.0	1.5	0.7	0.9
Hand grip strength (right)	0.0	0.1	0.2	-0.0	0.2	-0.5	0.3	0.1	0.3	0.3	0.2	-0.1	0.0	0.3	0.3	-0.3	0.1	0.3	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.3	-0.4	0.6	0.5	0.3	0.3	0.3	0.3	0.3	0.1	0.2	0.3	0.3	0.1	0.5	0.4	0.2
Qualifications: None of the above	0.0	0.0	0.4	-0.6	0.1	-0.2	0.1	0.2	0.0	0.1	0.1	-0.3	-0.0	-0.1	0.0	-0.2	0.1	-0.2	0.1
Trunk fat-free mass	0.0	0.3	2.9	0.6	0.3	1.0	0.0	0.1	0.1	-0.0	0.0	-1.7	0.2	0.2	0.0	0.1	-0.1	0.0	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.2	0.5	0.2	0.2	0.1	0.0	0.1	0.1	0.1	-0.4	-0.0	0.1	0.1	-0.1	-0.1	0.3	0.1
Medication: Lansoprazole	0.0	0.0	0.1	0.1	0.2	0.1	0.2	0.1	0.2	0.2	0.2	0.2	0.1	0.2	0.2	-0.0	-0.2	0.2	0.2
Trunk predicted mass	0.0	0.3	2.9	0.5	0.3	1.0	0.0	0.0	0.0	-0.0	-0.0	-1.7	0.2	0.2	0.0	0.0	-0.1	-0.0	-0.0
Length of working week for main job	0.0	0.1	0.2	-0.4	-0.1	-0.0	-0.2	-0.2	-0.2	-0.2	-0.2	0.2	-0.2	-0.3	-0.3	0.3	-0.3	0.0	-0.2
Peak expiratory flow (PEF)	0.0	0.1	0.6	0.8	0.1	0.6	-0.2	-0.2	-0.2	-0.1	-0.2	-0.3	-0.1	-0.1	-0.1	-0.0	-0.4	-0.1	-0.2
Loud music exposure frequency	0.0	0.0	0.4	-0.2	0.2	-0.3	0.0	0.0	0.0	0.0	0.0	-0.7	0.0	0.0	0.1	0.2	0.2	0.2	0.1
Medication: Ibuprofen	0.0	0.0	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.0	0.1	0.1	0.3	0.1	0.3	0.1
Friendships satisfaction	0.0	0.1	0.7	-0.3	-0.1	-0.8	-0.1	-0.0	-0.1	-0.2	-0.1	0.0	-0.0	-0.1	-0.1	0.2	0.0	-0.2	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.0	0.1	0.4	-0.4	-0.0	-0.6	0.1	0.0	0.1	0.1	0.1	-0.6	-0.2	-0.1	0.1	0.5	0.0	0.0	0.0
Back pain experienced in last month	0.0	0.1	0.3	-0.5	-0.2	-0.5	-0.2	-0.1	-0.1	-0.2	-0.2	-0.1	-0.0	-0.0	-0.1	-0.1	-0.2	-0.2	-0.2

Hub : Genes

KRT1

Models

Trait associations