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chr12:53,991,321-58,303,535

Best TWAS P=8.68e-34 · Best GWAS P=7.67e-40 conditioned to 0.000486

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RPS26	0.48	0.62	lasso	5	0.63	5.9e-99	10.92	11.2	5.3e-29	-0.04	1.00	0.00	FALSE
2	GTEx	Artery Aorta	SUOX	0.36	0.30	lasso	7	0.35	3.8e-20	10.94	-10.7	1.3e-26	0.03	0.99	0.01	FALSE
3	GTEx	Artery Tibial	LRP1	0.15	0.12	lasso	2	0.10	3.9e-08	6.00	-5.8	5.9e-09	0.18	0.98	0.02	FALSE
4	GTEx	Artery Tibial	SUOX	0.18	0.14	enet	23	0.18	2.1e-14	11.06	-9.8	1.1e-22	0.01	0.88	0.12	FALSE
5	GTEx	Artery Tibial	RPS26	0.07	0.02	enet	5	0.01	3.5e-02	10.92	10.6	4.3e-26	-0.04	0.15	0.48	FALSE
6	GTEx	Brain Cerebellum	SUOX	0.24	0.20	lasso	6	0.20	1.2e-06	10.94	-10.0	2.3e-23	0.04	0.21	0.64	FALSE
7	GTEx	Brain Cortex	SUOX	0.16	0.11	lasso	4	0.10	1.1e-03	10.94	-10.8	2.5e-27	0.04	0.04	0.58	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	SUOX	0.18	0.08	lasso	4	0.10	1.1e-03	10.94	-9.3	1.3e-20	0.04	0.05	0.56	FALSE
9	GTEx	Breast Mammary Tissue	RPS26	0.29	0.05	enet	37	0.12	9.4e-07	10.92	9.0	2.1e-19	-0.08	0.74	0.25	FALSE
10	GTEx	Breast Mammary Tissue (Female)	RPS26	0.20	0.11	lasso	3	0.10	6.6e-04	10.94	10.2	2.9e-24	-0.07	0.04	0.34	FALSE
11	GTEx	Cells Transformed fibroblasts	RPS26	0.11	0.08	enet	15	0.09	3.4e-07	10.16	10.3	5.2e-25	-0.04	0.92	0.08	FALSE
12	GTEx	Colon Sigmoid	ITGA7	0.17	0.00	enet	15	0.14	1.0e-05	-0.60	-5.2	2.6e-07	0.06	0.10	0.23	FALSE
13	GTEx	Colon Sigmoid	SUOX	0.23	0.18	lasso	4	0.15	7.9e-06	10.94	-11.1	8.2e-29	0.04	0.07	0.92	FALSE
14	GTEx	Colon Transverse	SUOX	0.24	0.22	enet	24	0.25	3.8e-12	10.94	-7.6	3.7e-14	0.01	0.96	0.03	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	SUOX	0.20	0.16	lasso	5	0.19	2.7e-07	11.06	-10.9	9.8e-28	0.04	0.22	0.76	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	WIBG	0.16	0.02	lasso	5	0.04	1.9e-02	-0.89	-8.3	9.9e-17	0.00	0.03	0.52	FALSE
17	GTEx	Esophagus Muscularis	LRP1	0.07	0.00	enet	12	0.00	3.6e-01	3.01	-5.7	1.0e-08	0.24	0.10	0.12	FALSE
18	GTEx	Esophagus Muscularis	SUOX	0.24	0.19	enet	16	0.15	2.3e-09	10.94	-10.5	6.2e-26	0.03	0.97	0.03	FALSE
19	GTEx	Esophagus Muscularis	RPS26	0.19	0.06	enet	46	0.05	9.3e-04	10.92	8.0	1.5e-15	-0.04	0.13	0.21	FALSE
20	GTEx	Heart Atrial Appendage	SUOX	0.09	0.10	enet	8	0.09	1.1e-04	10.92	-10.7	1.3e-26	0.05	0.05	0.86	FALSE
21	GTEx	Lung	SUOX	0.34	0.23	enet	38	0.26	4.6e-20	10.94	-7.8	7.7e-15	0.04	1.00	0.00	FALSE
22	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	12.05	-12.1	9.2e-34	0.02	0.00	1.00	TRUE
23	GTEx	Muscle Skeletal	SUOX	0.11	0.04	lasso	7	0.04	4.4e-05	10.94	-9.9	5.4e-23	0.04	0.24	0.69	FALSE
24	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	12.01	-12.1	8.7e-34	0.02	0.00	1.00	FALSE
25	GTEx	Nerve Tibial	SUOX	0.34	0.30	enet	22	0.35	8.5e-26	10.94	-10.0	1.8e-23	0.01	1.00	0.00	FALSE
26	GTEx	Nerve Tibial	RPS26	0.12	0.09	enet	7	0.11	3.0e-08	8.33	8.9	6.1e-19	-0.04	0.96	0.02	FALSE
27	GTEx	Nerve Tibial	CNPY2	0.07	0.00	enet	21	0.00	3.2e-01	8.33	-5.6	2.5e-08	-0.06	0.08	0.21	FALSE
28	GTEx	Ovary	SUOX	0.23	0.14	enet	12	0.21	8.4e-06	11.06	-9.9	5.2e-23	0.01	0.12	0.22	FALSE
29	GTEx	Ovary	RPS26	0.50	0.24	enet	25	0.22	5.0e-06	10.05	9.2	2.7e-20	-0.04	0.61	0.22	FALSE
30	GTEx	Pancreas	SUOX	0.30	0.20	enet	23	0.30	3.5e-13	11.06	-8.1	6.4e-16	-0.01	0.93	0.06	FALSE
31	GTEx	Pituitary	SUOX	0.44	0.13	enet	20	0.27	1.4e-07	10.16	-6.2	6.5e-10	0.01	0.08	0.50	FALSE
32	GTEx	Prostate	SUOX	0.22	0.04	enet	11	0.05	2.3e-02	11.06	-11.3	1.9e-29	0.04	0.03	0.82	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	SUOX	0.10	0.14	lasso	2	0.12	2.5e-07	10.94	-11.0	3.3e-28	0.04	0.07	0.92	FALSE
34	GTEx	Skin Sun Exposed Lower leg	SUOX	0.23	0.30	lasso	3	0.29	1.9e-24	10.94	-11.2	4.1e-29	0.04	1.00	0.00	FALSE
35	GTEx	Spleen	SUOX	0.34	0.31	enet	15	0.28	5.4e-08	10.94	-9.1	7.7e-20	0.01	0.22	0.61	FALSE
36	GTEx	Stomach	SUOX	0.15	0.17	enet	8	0.09	6.7e-05	10.94	-10.8	2.5e-27	0.04	0.49	0.46	FALSE
37	GTEx	Stomach	RPS26	0.16	0.08	enet	5	0.05	1.8e-03	10.94	10.1	4.2e-24	-0.05	0.14	0.30	FALSE
38	GTEx	Testis	SUOX	0.27	0.18	lasso	14	0.18	1.4e-08	10.94	-10.8	2.2e-27	0.04	0.24	0.75	FALSE
39	GTEx	Testis	RPS26	0.11	-0.01	enet	29	0.00	2.5e-01	2.08	5.4	7.8e-08	-0.01	0.05	0.38	FALSE
40	GTEx	Thyroid	SUOX	0.37	0.40	lasso	7	0.38	5.4e-31	10.94	-10.9	1.3e-27	0.04	1.00	0.00	FALSE
41	GTEx	Whole Blood	SUOX	0.07	0.01	enet	20	0.02	1.1e-02	10.92	-10.0	9.5e-24	0.02	0.09	0.76	FALSE
42	GTEx	Whole Blood	RPS26	0.05	0.05	lasso	1	0.05	3.4e-05	11.06	11.1	2.0e-28	-0.05	0.04	0.94	FALSE
43	METSIM	Adipose	IKZF4	0.04	0.04	enet	3	0.04	1.0e-06	10.05	10.3	1.0e-24	-0.04	0.98	0.01	FALSE
44	METSIM	Adipose	RPS26	0.30	0.40	lasso	5	0.41	7.2e-66	10.16	10.6	3.6e-26	-0.04	1.00	0.00	FALSE
45	METSIM	Adipose	SUOX	0.04	0.01	blup	288	0.02	1.1e-03	10.05	-7.7	1.1e-14	0.03	0.58	0.19	FALSE
46	YFS	Blood	NFE2	0.02	0.02	bslmm	400	0.09	1.6e-28	4.71	7.8	5.6e-15	-0.03	0.30	0.64	TRUE
47	YFS	Blood	SUOX	0.11	0.09	bslmm	269	0.09	3.4e-27	11.06	-10.4	1.6e-25	0.03	1.00	0.00	FALSE
48	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPS26	0.14	0.22	lasso	2	0.23	4.8e-19	10.16	10.4	1.6e-25	-0.04	0.99	0.01	FALSE
49	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS26	0.30	0.44	enet	10	0.45	5.2e-104	10.92	11.1	7.7e-29	-0.03	1.00	0.00	FALSE
50	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPS26	0.23	0.40	lasso	2	0.39	1.5e-20	10.92	11.2	3.6e-29	-0.03	0.68	0.32	FALSE
51	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	10.92	11.3	1.3e-29	-0.03	0.96	0.04	FALSE
52	The Cancer Genome Atlas	Esophageal Carcinoma	RPS26	0.19	0.13	lasso	5	0.11	2.4e-04	10.92	11.2	3.8e-29	-0.03	0.02	0.94	FALSE
53	The Cancer Genome Atlas	Glioblastoma Multiforme	RPS26	0.41	0.38	enet	9	0.39	7.9e-13	10.16	10.5	7.0e-26	-0.04	0.74	0.26	FALSE
54	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RPS26	0.17	0.29	lasso	4	0.29	6.2e-33	10.16	10.5	7.7e-26	-0.04	1.00	0.00	FALSE
55	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPR182	0.07	0.00	lasso	2	0.00	8.8e-02	-11.34	-11.6	5.2e-31	0.75	0.00	0.89	TRUE
56	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPS26	0.50	0.45	enet	13	0.52	1.4e-67	10.16	9.4	7.3e-21	-0.04	1.00	0.00	FALSE
57	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RAB5B	0.07	0.00	blup	33	0.03	7.0e-03	-1.03	6.0	2.3e-09	0.04	0.01	0.28	FALSE
58	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RPS26	0.27	0.38	enet	8	0.40	5.0e-24	10.92	11.1	7.4e-29	-0.04	0.99	0.01	FALSE
59	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERBB3	0.07	0.02	blup	29	0.05	2.1e-06	11.77	8.5	2.3e-17	0.00	0.00	1.00	FALSE
60	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPS26	0.31	0.53	enet	8	0.55	1.7e-74	10.92	10.9	8.0e-28	-0.04	1.00	0.00	FALSE
61	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RPS26	0.18	0.31	lasso	2	0.29	3.9e-14	10.92	10.9	1.4e-27	-0.03	1.00	0.00	FALSE
62	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB5B	0.03	0.02	enet	7	0.02	4.3e-03	12.05	10.1	7.1e-24	-0.06	0.00	0.87	FALSE
63	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS26	0.26	0.45	enet	9	0.47	3.6e-61	10.92	11.1	1.3e-28	-0.04	1.00	0.00	FALSE
64	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	10.92	11.2	3.7e-29	-0.03	1.00	0.00	FALSE
65	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPS26	0.30	0.20	lasso	4	0.24	3.9e-16	10.92	11.6	2.6e-31	-0.03	0.02	0.98	FALSE
66	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RPS26	0.36	0.44	lasso	7	0.42	2.4e-19	10.16	10.4	2.7e-25	-0.05	1.00	0.00	FALSE
67	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS26	0.47	0.43	lasso	2	0.44	3.2e-19	11.06	11.2	5.9e-29	-0.04	0.97	0.03	FALSE
68	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS26	0.33	0.52	enet	9	0.54	5.6e-66	10.92	11.2	6.5e-29	-0.03	1.00	0.00	FALSE
69	The Cancer Genome Atlas	Prostate Adenocarcinoma	SDR9C7	0.12	0.04	lasso	2	0.04	2.9e-05	-9.12	-8.8	1.5e-18	0.59	0.08	0.74	FALSE
70	The Cancer Genome Atlas	Prostate Adenocarcinoma	SILV	0.04	0.03	enet	6	0.04	7.9e-05	0.50	-5.4	8.3e-08	0.00	0.05	0.31	FALSE
71	The Cancer Genome Atlas	Rectum Adenocarcinoma	RPS26	0.24	0.18	lasso	2	0.20	1.9e-05	10.92	11.1	1.1e-28	-0.04	0.05	0.60	FALSE
72	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS26	0.23	0.31	lasso	3	0.30	2.4e-18	10.92	11.1	1.8e-28	-0.03	0.95	0.05	FALSE
73	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RPS26	0.28	0.15	lasso	2	0.17	3.0e-05	12.03	12.1	1.3e-33	-0.04	0.00	0.99	FALSE
74	The Cancer Genome Atlas	Stomach Adenocarcinoma	ERBB3	0.13	0.01	enet	12	0.03	1.9e-03	10.16	-5.1	3.0e-07	0.02	0.01	0.28	FALSE
75	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPS26	0.19	0.32	lasso	5	0.34	2.0e-25	10.16	10.7	6.8e-27	-0.04	1.00	0.00	FALSE
76	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS26	0.46	0.64	lasso	4	0.65	8.5e-30	10.92	11.2	5.7e-29	-0.03	0.89	0.11	FALSE
77	The Cancer Genome Atlas	Thyroid Carcinoma	RPS26	0.33	0.51	enet	19	0.50	7.3e-56	10.92	10.1	6.8e-24	-0.02	1.00	0.00	FALSE
78	The Cancer Genome Atlas	Thyroid Carcinoma	STAT6	0.04	0.01	blup	47	0.01	2.3e-02	6.62	7.1	1.1e-12	-0.27	0.08	0.06	TRUE
79	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM194A	0.15	0.07	blup	43	0.09	1.9e-09	5.09	7.0	3.5e-12	-0.44	0.69	0.11	FALSE
80	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RPS26	0.17	0.19	lasso	4	0.18	1.3e-05	10.92	11.2	3.0e-29	-0.04	0.03	0.96	FALSE