[Hub]/) : Traits : Blood Eosinophil Count :

chr1:160,452,218-161,885,352

Best TWAS P=5.28e-11 · Best GWAS P=2.38e-12 conditioned to 2.56e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous B4GALT3 0.21 0.05 enet 23 0.11 1.6e-09 5.8 6.3 2.8e-10 -0.59 0.10 0.90 FALSE
2 GTEx Cells Transformed fibroblasts PPOX 0.14 0.14 lasso 4 0.13 6.0e-10 5.8 5.6 2.3e-08 -0.27 0.78 0.22 FALSE
3 GTEx Cells Transformed fibroblasts B4GALT3 0.31 0.28 enet 16 0.30 2.0e-22 5.8 6.6 5.3e-11 -0.42 0.77 0.23 TRUE
4 GTEx Cells Transformed fibroblasts ADAMTS4 0.35 0.22 lasso 7 0.26 1.5e-19 5.8 6.5 7.4e-11 -0.39 0.80 0.20 FALSE
5 GTEx Cells Transformed fibroblasts NDUFS2 0.11 0.07 lasso 3 0.10 1.2e-07 -5.1 6.1 8.3e-10 -0.58 0.08 0.88 FALSE
6 GTEx Nerve Tibial B4GALT3 0.14 0.04 lasso 3 0.04 1.5e-03 5.8 5.3 1.3e-07 -0.21 0.09 0.33 FALSE
7 METSIM Adipose FCER1G 0.15 0.11 enet 15 0.12 6.3e-17 5.8 6.5 1.1e-10 -0.37 0.69 0.31 FALSE
8 NTR Blood FCER1G 0.17 0.14 lasso 6 0.16 3.4e-49 5.8 5.3 1.5e-07 -0.19 0.80 0.20 FALSE
9 YFS Blood FCER1G 0.46 0.42 lasso 8 0.45 4.2e-166 5.8 6.4 2.0e-10 -0.33 0.79 0.21 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma FCER1G 0.03 0.02 lasso 4 0.03 1.8e-06 -4.6 6.0 2.7e-09 -0.49 0.93 0.03 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FCER1G 0.04 0.00 enet 11 0.02 4.2e-03 -3.5 5.3 1.1e-07 -0.67 0.02 0.85 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma FCER1G 0.06 0.02 blup 71 0.05 2.7e-06 -4.4 6.5 9.7e-11 -0.50 0.33 0.26 FALSE