TWAS hub - B4GALT3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2150	0.0600	6.3e-06	0.048	NA	0.113	NA	0.112	8.3e-05	NA	1.6e-09	NA	1.9e-09
2	GTEx	Artery Aorta	0.0820	0.0380	9.7e-03	0.016	NA	-0.003	NA	0.011	4.2e-02	NA	5.2e-01	NA	8.1e-02
3	GTEx	Cells Transformed fibroblasts	0.3100	0.0510	1.2e-13	0.276	NA	0.295	NA	0.273	8.3e-21	NA	2.0e-22	NA	1.4e-20
4	GTEx	Nerve Tibial	0.1382	0.0554	7.3e-03	0.037	NA	0.028	NA	0.035	1.2e-03	NA	4.4e-03	NA	1.5e-03
5	METSIM	Adipose	0.0494	0.0194	3.9e-04	0.025	0.020	0.036	0.027	0.037	8.8e-05	5.0e-04	3.2e-06	5.9e-05	2.7e-06
6	YFS	Blood	0.0366	0.0139	2.4e-05	0.022	0.015	0.014	0.018	0.022	9.7e-08	7.3e-06	1.5e-05	8.4e-07	7.3e-08
7	TCGA	Brain Lower Grade Glioma	0.0310	0.0170	2.9e-03	0.028	0.013	0.007	NA	0.014	3.4e-04	1.0e-02	4.8e-02	NA	8.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7
Alzheimer’s Disease (including proxy)	12.9	18.8	28.2	-4.7	-0.1	-5.3	-4.8	-4.2	-4.8	-4.3
Alzheimer’s Disease (in mother)	7.7	9.0	13.2	-3.0	0.7	-3.6	-3.1	-2.8	-3.4	-3.3
Mouth/teeth dental problems: Mouth ulcers	6.2	9.8	21.0	-2.7	-1.2	-1.9	-0.9	-3.9	-4.6	-4.4
Hayfever/allergic rhinitis (self-reported)	5.6	7.4	21.6	3.2	-1.9	4.6	4.0	-0.5	0.2	-0.4
Lupus	5.0	7.6	19.2	-3.9	0.8	-2.9	-4.4	-2.1	-1.9	-1.3
Allergy or Eczema	4.9	12.9	38.4	4.3	-1.2	6.2	5.3	1.3	1.5	0.8
Mouth/teeth dental problems: Dentures	4.8	8.0	24.5	2.9	0.3	5.0	4.1	1.3	1.9	1.0
Alzheimer’s Disease (in father)	4.4	4.8	7.0	-2.1	-1.5	-2.3	-1.9	-2.4	-2.4	-2.6
Allergy	4.3	9.8	29.4	-4.1	0.6	-5.4	-4.4	-1.1	-1.2	0.2
Asthma (self-reported)	4.3	8.7	21.1	3.7	-0.8	4.6	4.5	1.3	1.6	1.0
Hayfever, allergic rhinitis or eczema	4.2	9.0	29.2	3.6	-1.3	5.4	3.9	1.2	1.6	0.7
Asthma	4.2	8.3	20.4	3.7	-0.6	4.5	4.4	1.2	1.4	0.8
Blood White Count	3.5	26.1	42.4	6.4	3.6	5.8	3.7	5.8	6.5	2.3
Respiratory disease	3.2	7.1	19.7	3.4	0.3	4.1	4.4	0.6	0.8	0.4
Tinnitus: Yes, now most or all of the time	3.2	3.8	6.6	1.6	0.9	1.9	0.9	2.4	2.5	2.6
Blood Eosinophil Count	3.0	22.9	43.0	6.3	-4.1	6.6	5.3	4.0	4.2	0.4
Birth weight of first child	2.9	5.2	10.4	-3.2	-0.2	-2.0	-3.2	-2.1	-1.8	-2.0
Medication: Ventolin 100micrograms inhaler	2.9	3.7	13.7	2.0	-1.0	3.7	2.4	0.1	1.2	0.5
Mouth/teeth dental problems: Loose teeth	2.7	3.2	8.6	2.3	-0.0	2.9	2.6	0.2	0.8	1.1
Bipolar Disorder (2018)	2.6	4.2	12.4	-1.3	1.4	-1.6	-1.8	-1.6	-2.3	-3.5
Mouth/teeth dental problems	2.6	3.9	8.6	-1.0	0.1	-1.9	-2.9	2.0	2.1	2.4
Waist Hip Ratio (WHR)	2.5	11.1	16.5	-3.3	-2.2	-3.5	-2.5	-3.5	-3.9	-4.1
Wears glasses or contact lenses	2.2	2.6	5.9	-1.7	0.9	-1.5	0.0	-2.2	-2.4	-1.1
Hearing aid user	2.2	2.5	5.8	-2.4	1.6	-0.8	-1.8	-1.5	-1.4	-1.0
Bipolar Disorder or Schizophrenia	2.1	5.1	12.3	-1.7	0.9	-2.1	-2.9	-1.7	-2.0	-3.5
Schizophrenia vs Biploar Disorder	2.1	2.7	4.6	2.1	-1.5	1.9	1.3	1.7	1.8	0.9
Irritable Bowel Disease (IBD)	2.1	4.9	14.4	1.8	3.6	0.6	1.3	-0.1	-1.3	-3.8
Ulcerative Colitis (UC)	2.1	4.0	11.4	1.1	3.4	-0.2	0.9	-0.7	-2.0	-3.1
Rheumatoid Arthritis	2.1	2.9	9.8	2.4	0.2	1.7	3.1	0.2	-0.3	-1.2
Medication: Ramipril	2.1	2.7	9.2	1.0	0.9	0.6	-0.6	3.0	2.3	1.3
Noisy workplace	2.1	2.6	6.0	1.6	0.5	1.3	0.7	2.3	2.4	1.3
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	3.8	-1.9	-1.9	-1.7	-1.8	-0.6	-0.4	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	5.3	-0.8	0.7	-1.9	-0.3	-2.3	-2.3	-1.4
Risk taking	1.9	2.8	8.6	-1.3	-0.9	-2.4	-2.9	-0.2	-0.3	-1.5
Age started oral contraceptive pill	1.9	2.3	3.8	-1.8	-0.0	-1.9	-1.1	-1.9	-1.8	-1.0
Diabetes (mother)	1.8	2.4	4.0	-2.0	-0.6	-1.6	-1.5	-1.8	-1.9	-0.8
Average weekly fortified wine intake	1.8	2.1	4.3	-1.2	1.4	-1.1	-0.8	-2.1	-1.8	-1.4
Multivitamins +/- minerals	1.8	2.3	5.4	1.6	1.4	1.3	0.3	2.3	2.2	-0.1
Medication: Simvastatin	1.8	2.6	6.1	2.5	2.3	0.7	0.9	1.6	1.2	-1.2
Exposure to tobacco smoke at home	1.8	2.0	5.7	0.4	-1.1	0.3	-0.7	1.7	2.4	1.9
Ever taken oral contraceptive pill	1.8	2.0	3.8	1.6	1.8	1.0	0.5	1.9	1.8	-0.3
Bipolar Disorder (2011)	1.7	1.6	2.7	-1.4	0.4	-1.7	-1.0	-1.3	-1.4	-1.4
HbA1C	1.7	1.9	6.1	1.8	-1.1	2.5	1.3	0.7	0.8	-0.2
Financial difficulties in last 2 years	1.7	2.3	6.2	-1.0	1.3	-2.5	-2.2	-0.6	-1.1	-0.9
Qualifications: O levels/GCSEs or equivalent	1.7	2.8	7.4	-1.9	1.7	-2.7	-2.2	0.1	-0.7	-0.0
Crohns Disease (2017)	1.6	3.6	9.1	1.8	3.0	1.5	1.2	0.4	0.0	-3.0
Mean Putamen Volume	1.6	1.8	4.4	1.4	2.1	0.3	1.2	1.8	1.2	-0.5
Ulcerative Colitis	1.6	2.4	8.0	1.6	2.8	-0.1	0.8	0.8	-0.4	-2.2
Mouth/teeth dental problems: Bleeding gums	1.6	2.0	4.1	0.2	-0.4	-0.6	1.4	-2.0	-2.0	-1.9
Wheeze or whistling in the chest in last year	1.6	2.9	5.5	1.7	-2.4	2.1	2.1	1.1	1.1	0.7
Number of children fathered	1.6	1.8	3.8	0.8	1.6	1.1	0.7	1.0	1.7	2.0
Medication: Seretide 50 evohaler	1.6	1.8	3.9	1.1	-0.7	1.5	0.2	1.6	2.0	1.5
Ever had bowel cancer screening	1.6	1.9	11.9	0.9	3.5	-0.6	0.4	0.3	0.1	-0.3
Osteoporosis (self-reported)	1.6	2.0	6.3	-0.9	2.5	-0.3	-1.5	0.9	1.1	1.6
Hand grip strength (left)	1.5	4.0	8.9	2.3	0.6	2.5	0.6	2.1	3.0	1.6
Taking other prescription medications	1.5	2.3	4.3	2.1	1.1	1.8	1.7	1.2	1.1	1.4
Medication: Cholesterol lowering	1.5	2.3	7.8	1.9	2.8	1.0	1.1	1.0	1.0	-0.6
Unable to work because of sickness or disability	1.5	1.9	3.8	-1.1	1.7	-1.9	-1.9	-0.8	-1.0	-0.3
Blood Platelet Count	1.4	15.9	38.7	-6.2	-3.2	-4.0	-4.3	-3.9	-3.2	-1.7
Stomach or abdominal pain in last month	1.4	1.7	3.0	1.7	1.3	1.4	1.0	1.4	1.0	-1.3
Heart attack	1.4	1.8	5.2	1.9	0.6	2.3	1.6	0.7	0.9	0.4
Illnesses of mother	1.4	1.8	3.1	1.0	-0.3	1.4	1.5	1.4	1.8	1.4
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	7.9	-2.0	1.0	-1.1	-2.8	0.4	0.5	2.2
Blood Red Count	1.3	12.7	32.9	5.7	0.0	3.8	4.1	3.4	3.4	1.2
Hearing difficulty/problems: Yes	1.3	1.9	3.7	1.2	1.3	1.1	0.2	1.7	1.9	1.6
Relative age voice broke	1.3	2.0	3.3	-1.8	-1.6	-1.4	-1.8	-0.8	-0.6	-1.4
Pain all over the body in last month	1.3	1.4	3.8	0.0	2.0	-0.8	-1.4	1.2	1.4	0.2
Comparative body size at age 10	1.3	3.5	9.1	0.2	2.0	0.5	-0.8	2.6	3.0	1.9
Supplements: Vitamin C	1.3	1.5	3.7	-1.8	-0.4	-0.7	-1.7	-0.3	-0.0	1.9
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.9	1.1	1.2	1.7	1.6	0.6	1.0	0.9
Pack years adult smoking proportion	1.2	1.9	4.6	-1.4	-0.1	-1.5	-1.0	-2.1	-1.6	-0.6
Hand grip strength (right)	1.2	3.1	9.4	1.5	1.0	1.7	-0.6	2.1	3.1	1.2
Nervous feelings	1.2	2.3	6.0	-0.8	0.8	-2.1	-0.9	-1.2	-1.4	-2.4
Medication: Aspirin	1.2	1.6	3.6	1.6	0.9	1.9	1.3	0.8	0.8	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	3.3	1.3	1.2	1.8	1.0	0.9	1.2	0.4
Pain type(s) experienced in last month: Hip pain	1.2	1.5	4.6	-0.5	-0.7	0.7	0.5	-2.1	-1.6	-1.5
Medication: Atorvastatin	1.2	1.5	3.1	1.4	1.8	1.5	1.7	0.2	0.4	0.2
Fractured/broken bones in last 5 years	1.2	1.5	8.4	-0.1	-2.9	1.0	-0.5	-0.3	0.9	0.5
Myopia	1.2	1.7	7.6	-0.4	-2.8	-0.1	-0.3	1.3	1.0	1.3
Severe depression (siblings)	1.1	1.3	2.7	-1.0	0.0	-1.0	-1.3	-1.0	-1.2	-1.6
Medication: Levothyroxine sodium	1.1	1.9	4.6	-1.9	0.9	-0.7	-2.1	0.1	0.3	1.9
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	9.7	-1.3	-3.1	-0.3	-0.1	-0.8	-0.6	-0.2
High blood pressure (siblings)	1.1	1.6	7.0	0.2	2.7	-0.4	-1.8	0.2	1.0	0.5
High cholesterol (Self-reported)	1.1	1.9	8.5	1.4	2.9	0.3	0.3	1.1	1.1	-0.7
Basal cell carcinoma (self-reported)	1.1	1.3	2.2	1.4	1.1	0.9	1.5	0.9	1.3	0.7
Neuroticism (2016)	1.0	1.4	8.5	-0.3	-0.1	-0.5	-0.1	-0.4	-1.0	-2.9
Hypothyroidism (self reported)	1.0	2.2	6.7	-1.9	0.0	-1.1	-2.6	0.2	0.2	2.0
Vitamin and mineral supplements	1.0	1.3	2.9	-0.6	-1.1	-1.3	0.1	-1.7	-1.7	-0.6
Medication: Metformin	1.0	1.4	3.6	-0.8	1.1	-1.2	-1.9	0.3	0.3	-1.7
Waist circumference	1.0	3.8	12.7	-2.4	0.2	-2.7	-3.6	-0.7	0.1	0.0
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	3.8	0.8	-1.2	0.8	-0.1	1.0	1.3	2.0
Depression (self-reported)	1.0	1.2	5.9	0.5	2.4	-0.1	0.6	0.4	0.8	-0.9
Worry too long after embarrassment	1.0	1.7	3.0	-1.4	-0.8	-1.4	-1.2	-1.7	-1.5	-0.7
Medication: Lisinopril	1.0	1.3	3.2	-0.2	1.6	-0.7	-0.6	-1.0	-1.3	-1.8
Alcohol drinker status: Never	1.0	1.3	3.0	-1.1	-1.7	-1.3	-1.6	0.0	-0.4	-0.4
Cholesterol lowering medication	1.0	1.5	3.5	1.9	1.8	0.8	1.1	1.1	0.8	-0.5
Pack years of smoking	1.0	1.5	3.8	-1.5	-0.2	-1.3	-1.0	-1.9	-1.2	-0.4
Depression (Nagel 2018)	0.9	1.4	4.5	0.8	2.1	0.1	0.5	1.5	1.4	0.4
Schizophrenia (2018)	0.9	1.8	5.3	-1.2	0.1	-1.4	-2.3	-0.9	-0.8	-1.6
Coronary Artery Disease (CAD)	0.9	1.0	2.0	-0.7	0.5	-1.4	-0.2	-1.2	-1.4	-0.9
Schizophrenia (2014)	0.9	1.9	6.9	-1.6	-0.8	-1.4	-2.6	-0.6	-0.4	-0.9
Supplements: Zinc	0.9	1.0	4.2	-1.4	-0.4	-0.8	-2.1	-0.5	0.0	-0.2
Had menopause	0.9	1.1	3.0	-0.7	-0.5	-0.3	-0.2	-1.7	-1.1	-1.6
Illnesses of siblings	0.9	1.3	5.6	-0.7	-2.4	0.3	1.1	-0.7	-1.0	0.2
Qualifications: A levels/AS levels or equivalent	0.9	1.9	6.0	-0.6	0.0	-1.0	-0.1	-1.0	-2.3	-2.5
Prospective memory result	0.9	1.1	2.9	1.6	0.3	1.1	1.7	0.5	1.0	0.0
Suffer from ‘nerves’	0.9	1.5	2.9	-1.2	1.6	-1.7	-1.7	-0.3	-0.2	-0.8
Age at last live birth	0.9	1.3	3.0	-0.2	-1.7	-0.6	0.5	-1.1	-1.5	-1.3
Family relationship satisfaction	0.9	1.1	1.8	0.0	0.8	-1.3	-1.0	1.3	1.2	1.1
Illnesses of siblings: Diabetes	0.9	1.1	2.7	0.0	0.7	-1.6	-1.6	1.1	0.7	-0.2
Eye problems/disorders: Cataract	0.9	1.0	5.4	0.0	2.3	0.7	0.2	-0.9	-0.5	-0.4
Medication: Bendroflumethiazide	0.9	1.3	5.8	-0.2	2.4	-0.3	-1.1	1.0	1.0	0.2
Illnesses of father: High blood pressure	0.9	1.1	3.3	0.9	1.8	-1.0	-1.0	1.0	0.7	0.2
Ever depressed for a whole week	0.9	1.1	2.3	-1.2	-0.5	-1.5	-1.5	-0.7	-0.3	-0.9
Chronotype (morning person)	0.8	1.8	6.0	1.1	0.3	2.2	2.4	-0.4	-0.1	0.4
Trunk fat percentage	0.8	3.2	8.3	-0.3	1.1	-1.1	-2.9	1.9	2.7	0.9
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	3.2	0.9	0.8	0.7	0.5	1.0	0.8	-1.8
Number of incorrect matches in round	0.8	1.3	2.4	0.7	1.5	0.7	0.8	1.2	1.6	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	3.0	0.6	1.6	-0.2	-0.7	1.7	1.5	-0.7
Arm fat percentage (right)	0.8	3.1	6.9	-0.3	1.7	-0.8	-2.6	1.8	2.6	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	3.4	0.5	1.3	-0.2	-0.3	1.9	1.9	0.8
Tense / ‘highly strung’	0.8	1.3	3.9	-1.0	0.3	-1.9	-2.0	-0.6	-0.1	-0.7
Medication: Paracetamol	0.8	1.3	2.6	-0.2	-0.3	-0.6	-1.6	1.6	1.5	1.1
Birth weight	0.8	1.7	3.8	-1.0	-1.0	0.3	-1.7	0.4	1.8	1.9
Body fat percentage	0.8	3.1	8.6	-0.4	1.4	-1.0	-2.9	1.7	2.6	0.7
Medication: Ibuprofen	0.8	0.9	2.5	0.8	-1.2	0.5	0.2	0.8	0.9	1.6
Leg pain on walking	0.8	1.0	1.8	-0.4	1.0	-1.3	-1.1	-0.6	-1.0	-1.2
Long-standing illness, disability or infirmity	0.8	1.3	2.9	1.7	1.5	0.3	0.3	1.2	1.1	1.0
Qualifications: nursing, teaching	0.8	1.3	5.2	0.6	2.3	-0.2	0.3	0.3	0.0	-1.8
Medication: Aspirin	0.8	1.0	3.0	1.2	-0.1	1.7	1.6	0.1	0.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	6.6	0.7	0.0	0.1	-0.7	2.6	1.9	-0.1
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.7	1.4	0.8	1.6	1.1	0.4	0.5	0.2
Ovarian Cancer	0.7	0.9	3.2	0.7	0.5	1.8	0.2	0.9	1.2	0.5
Crohns Disease (2012)	0.7	1.1	2.5	1.1	1.4	1.1	0.8	0.1	-0.2	-1.6
LDL Cholesterol	0.7	1.2	3.2	1.2	1.8	-0.1	1.5	-0.3	-0.8	-0.8
BMI	0.7	4.1	10.4	0.5	1.3	-0.3	-1.9	2.5	3.2	2.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.0	0.9	1.3	0.0	0.1	1.4	1.1	-1.0
Fed-up feelings	0.7	1.2	2.2	-1.1	1.4	-1.5	-0.6	-0.4	-1.1	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.1	0.4	1.8	-0.3	-0.3	1.2	1.2	0.0
High blood pressure	0.7	1.9	5.3	-1.0	1.7	-1.9	-2.3	-0.2	-0.3	0.6
Trunk fat mass	0.7	3.2	10.7	-0.9	0.9	-1.3	-3.3	1.3	2.2	1.1
Trunk fat-free mass	0.7	3.7	7.6	-2.8	-1.1	-2.0	-2.6	-2.0	-1.3	0.7
Arm fat mass (right)	0.7	2.8	10.1	-1.1	0.6	-1.3	-3.2	1.0	1.9	1.2
Breastfed as a baby	0.7	0.9	3.1	-0.6	-0.8	-1.7	-1.2	0.4	0.3	-0.4
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.8	1.3	-0.9	0.6	0.0	1.3	0.8	-0.7
Exposure to tobacco smoke outside home	0.7	0.9	3.0	-0.8	-0.1	-0.6	-1.2	0.6	0.5	1.7
Emphysema/chronic bronchitis	0.7	0.8	2.5	0.1	1.6	-0.3	-0.1	-0.6	-1.1	-1.3
Medication for pain relief, constipation, heartburn	0.7	1.1	2.9	-0.8	-0.3	-0.8	0.6	-1.7	-1.6	-1.0
Medication: Blood pressure	0.7	1.2	5.1	0.8	2.3	0.2	0.1	0.5	0.3	1.6
Whole body fat mass	0.7	3.0	11.4	-1.2	0.7	-1.6	-3.4	0.9	1.8	0.9
Chest pain or discomfort	0.7	1.0	2.2	-0.9	-1.5	-0.5	-1.2	-1.1	-0.9	-0.6
Arm fat percentage (left)	0.7	3.0	7.6	-0.3	1.5	-0.7	-2.8	1.8	2.5	0.9
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.4	-1.0	-1.1	-1.2	-0.9	-0.8	-0.8	0.3
Back pain experienced in last month	0.7	1.0	3.1	-0.7	-0.9	-0.1	-0.9	-1.8	-1.0	-1.0
Mineral and other dietary supplements	0.7	0.9	2.7	0.1	-0.1	-1.6	0.3	-0.6	-1.3	-1.1
Arm fat mass (left)	0.7	3.0	10.6	-1.1	0.9	-1.4	-3.3	1.1	2.0	1.2
Miserableness	0.7	1.3	3.6	-0.6	1.9	-1.4	-0.8	0.4	-0.4	-1.5
Guilty feelings	0.7	1.1	3.0	1.3	-0.4	1.3	1.7	-0.2	0.4	-1.0
Financial situation satisfaction	0.7	0.9	3.5	-0.3	-1.1	-1.9	-1.2	0.4	0.3	-0.1
Age at First Birth	0.6	0.8	2.9	-0.7	-0.2	-0.3	0.0	-1.1	-1.7	-0.9
HDL Cholesterol	0.6	1.0	2.2	-0.3	-1.2	-1.1	0.5	-1.2	-1.5	-0.4
Triglycerides	0.6	1.0	2.6	1.1	0.4	1.1	0.9	1.6	1.0	0.0
Number of treatments/medications taken	0.6	1.0	1.9	1.4	1.0	1.2	1.1	0.5	0.5	1.0
Average weekly spirits intake	0.6	0.8	1.9	0.3	-1.4	-0.2	0.9	-1.0	-1.0	-0.7
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.0	-0.6	1.4	-0.3	-1.3	0.6	1.0	0.0
Diabetes (father)	0.6	0.7	1.1	-0.8	-1.1	-1.0	-0.9	-0.5	-0.5	-0.9
Leg fat-free mass (left)	0.6	2.9	8.0	-2.3	-0.4	-2.0	-2.8	-1.3	-0.6	0.9
Medication: Atenolol	0.6	0.7	2.3	-0.7	1.5	0.2	-0.5	-0.3	0.1	1.3
Hair/balding pattern: Pattern 2	0.6	0.7	2.5	-0.3	1.6	-0.3	-0.5	-0.1	0.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.0	-0.2	-0.8	-1.1	-0.8	0.1	-0.3	-1.4
Trunk predicted mass	0.6	3.7	7.6	-2.8	-1.1	-2.0	-2.6	-2.0	-1.3	0.6
Length of working week for main job	0.6	0.6	2.2	0.7	-1.0	0.1	0.2	0.9	1.5	-0.0
Peak expiratory flow (PEF)	0.6	1.4	3.0	1.2	0.7	1.6	1.7	0.9	0.8	0.8
Headache pain in last month	0.6	1.0	2.5	0.6	1.2	0.5	-0.5	1.5	1.6	0.5
Leg fat percentage (right)	0.6	2.0	6.4	-0.4	1.2	-0.8	-2.5	1.2	1.9	0.6
Arm fat-free mass (right)	0.6	2.9	5.9	-2.3	-1.1	-1.8	-2.4	-1.7	-0.9	0.9
Health satisfaction	0.6	0.7	3.1	-0.6	0.3	-1.8	-1.1	0.5	0.1	-0.2
Leg fat mass (right)	0.6	2.3	9.7	-1.2	0.8	-1.4	-3.1	0.5	1.4	0.6
Arm predicted mass (right)	0.6	3.1	6.8	-2.4	-0.9	-1.9	-2.6	-1.8	-1.0	0.5
Overall health rating	0.6	1.3	3.0	0.4	1.1	0.3	-1.1	1.0	1.7	1.6
Knee pain experienced in last month	0.6	1.0	2.6	-1.0	-0.7	-0.2	0.0	-1.4	-1.6	0.8
Hypertension (Self-reported)	0.6	1.7	4.2	-0.8	1.9	-1.8	-2.0	-0.2	-0.3	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.4	0.4	-0.7	0.9	0.8	0.1	0.7	1.6
Illnesses of father: Heart disease	0.6	0.9	1.8	0.4	-1.0	0.3	1.1	-1.3	-1.1	-0.8
Whole body fat-free mass	0.6	3.3	6.9	-2.5	-0.8	-2.0	-2.6	-1.8	-1.0	0.8
Medication: Gliclazide	0.6	0.7	1.5	-0.4	0.2	-1.2	-1.0	0.6	1.2	0.4
Whole body water mass	0.6	3.4	7.5	-2.6	-0.9	-2.0	-2.7	-1.7	-1.0	0.9
Arm fat-free mass (left)	0.6	3.0	7.8	-2.4	-0.7	-2.0	-2.8	-1.3	-0.3	1.3
Commuting to job workplace: Cycle	0.6	0.7	4.2	-0.5	0.6	-0.1	0.0	0.1	-0.4	2.0
Leg fat mass (left)	0.6	2.2	9.3	-1.2	0.8	-1.3	-3.0	0.5	1.3	0.6
Arm predicted mass (left)	0.6	2.9	6.4	-2.4	-0.9	-1.8	-2.5	-1.5	-0.5	1.2
Worry (Nagel 2018)	0.5	1.1	1.9	-1.3	0.2	-1.4	-0.9	-0.9	-1.0	-1.3
Major Depression (MDD)	0.5	0.6	1.0	0.3	0.9	-1.0	-0.6	1.0	0.0	-1.0
Body Mass Index (BMI) (2010)	0.5	0.7	1.5	0.8	0.3	0.9	0.3	0.9	1.2	1.0
Fasting Glucose	0.5	0.6	1.9	0.5	-0.0	0.9	0.6	0.8	-0.3	1.4
Type 2 Diabetes (T2D) (2012)	0.5	0.5	2.7	0.3	1.6	0.0	0.3	-0.5	-0.7	-0.5
Heel T-Score	0.5	3.8	10.0	-1.3	1.0	-1.4	-1.6	-2.4	-2.0	-3.2
Type 2 Diabetes (T2D) (2018)	0.5	1.0	3.1	-1.2	0.3	-1.2	-1.8	-0.1	0.2	-1.0
Neuroticism	0.5	1.1	4.4	-1.1	0.2	-1.0	-0.6	-0.8	-0.5	-2.1
Ever had hysterectomy (womb removed)	0.5	0.5	2.3	-0.2	1.5	-0.2	-0.6	0.6	0.6	0.3
Medication for hormone replacement therapy	0.5	0.5	2.0	-0.2	-0.4	1.0	-0.2	-0.6	-0.1	-1.4
Age when periods started (menarche)	0.5	1.2	5.0	-0.1	-2.2	0.3	-0.8	-0.1	-0.2	-1.6
Serious illness, injury or assault to yourself	0.5	0.7	2.2	0.6	-0.6	1.1	1.5	-0.1	0.6	0.3
Supplements: Glucosamine	0.5	0.6	3.2	-0.6	1.8	0.5	-0.5	-0.0	0.2	0.6
Leg predicted mass (left)	0.5	2.8	7.7	-2.3	-0.4	-2.0	-2.8	-1.3	-0.6	0.9
Alcohol usually taken with meals	0.5	0.7	1.7	-0.7	-0.6	0.2	0.4	-1.1	-1.3	-1.2
Weight	0.5	2.5	9.3	-1.7	0.1	-1.6	-3.1	-0.2	0.9	1.3
Father’s age at death	0.5	0.6	1.8	0.4	0.0	0.1	1.0	-0.7	-1.3	-1.0
Falls in the last year	0.5	0.7	2.1	-0.2	-1.4	-0.4	-0.9	-0.5	-0.1	-1.3
Hair/balding pattern: Pattern 3	0.5	0.7	1.5	0.5	-0.4	1.0	1.2	0.0	-0.7	-1.2
Number of live births	0.5	0.7	1.2	-1.1	-0.6	-0.4	-1.0	-1.1	-0.8	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.9	0.4	1.7	-0.5	0.9	-0.3	-0.6	-0.6
Qualifications: College or University degree	0.5	1.4	3.2	1.0	-0.9	0.7	1.7	-0.7	-1.1	-1.8
Eye problems/disorders: None of the above	0.5	0.6	3.3	-0.1	-1.8	-0.6	-0.2	0.8	0.2	-0.2
Migraine (self-reported)	0.5	0.6	1.4	-0.8	-0.1	-0.7	-1.2	-1.0	-0.5	0.6
Medication: Omeprazole	0.5	0.6	1.3	-0.8	-0.6	-0.4	-1.0	-0.9	-0.6	-1.1
Number of full sisters	0.5	0.6	3.0	-0.1	-0.1	-0.9	-1.7	-0.0	0.5	0.3
Leg fat-free mass (right)	0.5	2.7	6.4	-2.3	-0.4	-1.9	-2.5	-1.4	-0.6	0.9
Average weekly red wine intake	0.5	0.8	2.7	0.6	-1.6	0.6	1.2	-0.3	-0.2	-0.4
Loneliness, isolation	0.5	0.6	3.9	-0.2	2.0	0.1	-0.4	-0.1	0.1	0.6
Friendships satisfaction	0.5	0.6	1.8	-0.7	0.3	-1.3	-0.8	0.4	-0.1	1.0
Osteoarthritis (self-reported)	0.5	0.7	1.7	-1.0	1.0	-0.5	-0.7	-1.3	-0.3	0.5
Illnesses of father: None of the above (group 1)	0.5	0.6	1.5	-1.2	-0.5	-0.5	-1.0	0.8	0.5	0.5
Leg predicted mass (right)	0.5	2.6	6.2	-2.3	-0.4	-1.9	-2.5	-1.4	-0.6	1.0
Number of self-reported non-cancer illnesses	0.5	0.9	1.7	1.2	1.1	0.9	1.3	-0.5	-0.5	0.6
Medication: Blood pressure	0.5	0.9	2.8	-0.4	1.7	-0.1	-1.3	0.9	0.9	-0.1
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.3	-0.4	-0.9	1.5	-0.5	0.1	0.9	0.5
Basal metabolic rate	0.5	3.0	8.4	-2.4	-0.6	-1.9	-2.9	-1.3	-0.4	1.1
Leg fat percentage (left)	0.5	1.9	6.3	-0.6	1.4	-1.0	-2.5	0.9	1.7	0.4
Vascular/heart problems diagnosed by doctor	0.5	1.3	2.9	0.7	-1.7	1.3	1.6	0.6	0.8	-0.3
Supplements: Calcium	0.5	0.6	1.8	-0.8	-1.4	-0.2	-1.0	-0.5	-0.4	-0.1
Depressed Affect (Nagel 2018)	0.4	0.9	3.0	-1.1	1.7	-0.9	-0.6	-0.1	-0.6	-0.8
Breast Cancer	0.4	1.0	1.9	0.8	1.2	0.3	0.7	1.4	0.8	1.3
Systolic Blood Pressure	0.4	2.0	9.5	0.4	0.2	0.3	0.0	1.6	1.3	3.1
Systolic blood pressure, automated reading	0.4	1.0	2.7	-0.6	0.6	-0.4	-1.3	1.0	1.0	1.6
Medication: Co-codamol	0.4	0.5	1.3	0.6	1.1	-0.3	-0.8	0.1	0.6	-0.9
Current tobacco smoking	0.4	0.6	1.6	0.1	0.0	-0.6	0.6	-0.7	-1.1	-1.3
Body mass index (BMI)	0.4	1.7	6.0	-1.0	0.8	-1.1	-2.4	0.4	1.3	1.2
Hip circumference	0.4	1.9	5.4	-0.9	0.1	-0.8	-2.3	0.5	1.6	1.8
Time employed in main current job	0.4	0.5	1.3	1.1	-0.4	-0.3	0.2	0.8	0.9	-0.7
Alcohol intake versus 10 years previously	0.4	0.7	1.4	0.4	1.2	0.1	-0.7	1.2	1.1	-0.1
Blood clot in the leg (DVT)	0.4	0.5	1.6	0.3	-0.1	-0.5	-0.5	-0.6	-1.0	-1.2
Gout (self-reported)	0.4	0.6	1.2	1.1	-0.0	1.1	1.1	-0.2	-0.2	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.2	0.1	0.3	-0.4	-0.6	1.5	0.8	0.5
Age at first live birth	0.4	0.7	2.0	0.0	-0.7	0.0	0.9	-0.6	-1.4	-0.9
Angina (self-reported)	0.4	0.6	1.7	-1.0	-0.4	-0.2	-0.2	-1.3	-1.0	-0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.2	0.5	1.1	0.6	0.1	0.6	0.8	-0.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.2	-1.1	0.5	-0.6	-0.7	-0.5	-0.5	0.8
Diabetes diagnosed by doctor	0.4	0.7	2.1	-0.5	0.3	-0.9	-1.4	0.7	0.6	-0.9
Breast cancer (self-reported)	0.4	0.5	1.3	-0.6	-1.1	0.3	1.1	-0.4	-0.3	0.4
Mother’s age at death	0.4	0.5	1.2	-1.0	-0.8	-0.1	-0.4	-0.3	-0.1	-1.1
Medication: Paracetamol	0.4	0.6	1.6	-0.2	-0.2	-0.2	-0.6	1.2	1.1	1.1
Average weekly beer plus cider intake	0.4	0.5	2.6	-0.0	0.5	-1.6	-0.9	0.3	0.0	-0.1
Irritability	0.4	0.6	1.0	0.9	0.6	0.7	0.7	0.7	0.9	1.0
Diastolic blood pressure, automated reading	0.4	1.3	3.9	-0.8	-0.3	-2.0	-1.4	0.7	0.7	1.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.9	-0.8	-0.6	-0.2	-1.4	-0.3	0.0	-0.7
Pain experienced in last month	0.4	0.6	2.1	0.7	-0.8	0.7	1.5	0.7	0.3	0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.5	0.2	0.0	-0.5	-0.7	-0.6	-1.0	-1.2
Heart disease (siblings)	0.4	0.5	2.5	0.4	1.6	-0.5	0.2	0.0	0.3	-0.6
Impedance of whole body	0.4	1.8	4.8	1.9	0.2	0.5	0.4	2.2	1.4	-1.3
Reaction Time	0.3	0.6	1.7	-0.7	0.1	-0.9	-1.3	0.1	-0.5	-1.1
Cardiovascular Disease	0.3	0.8	2.6	1.0	1.6	-0.6	-0.6	0.7	0.8	0.7
Lung FEV1/FVC ratio	0.3	1.6	2.7	-1.0	1.4	-0.3	-1.6	1.5	1.0	-1.6
Lung FVC	0.3	1.3	3.7	1.0	1.9	-0.6	-0.2	1.8	0.6	-0.6
Tanning	0.3	3.2	5.8	1.7	-1.1	1.4	1.5	2.2	2.4	1.7
Sensitivity / hurt feelings	0.3	0.4	1.4	0.1	1.2	-1.0	0.3	-0.3	-0.3	-0.4
Relative age of first facial hair	0.3	0.6	2.2	-0.9	-0.1	-0.5	-1.5	0.2	0.3	-0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.7	0.1	0.8	0.3	-0.7	0.7	0.8	0.0
Angina	0.3	0.5	1.5	-0.6	-0.5	0.1	0.2	-1.2	-0.9	-0.4
Townsend deprivation index at recruitment	0.3	0.4	2.6	0.3	-1.6	0.1	-0.2	0.2	0.5	0.1
Maternal smoking around birth	0.3	0.5	0.9	-0.8	-0.9	-0.0	-0.2	-0.9	-0.5	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.5	-0.0	1.6	0.2	-0.2	-0.8	-0.3	-1.0
Chronic bronchitis/emphysema (father)	0.3	0.3	1.1	0.6	0.4	0.6	1.1	-0.4	-0.0	-0.4
Had other major operations	0.3	0.4	1.5	-0.3	1.2	-0.3	-0.9	0.4	0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.6	0.0	1.9	0.5	0.0	-0.2	0.2	-0.8
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.5	0.1	1.2	-0.1	0.1	0.2	0.4	-0.8
Qualifications: None of the above	0.3	0.6	2.4	-0.6	-1.0	0.0	-0.4	-0.2	0.4	1.6
Diabetes (self-reported)	0.3	0.5	1.5	0.6	0.1	0.1	-0.4	1.2	1.1	-0.4
Fluid intelligence score	0.3	0.6	1.4	-0.8	-1.2	-1.0	-0.4	0.0	-0.5	0.5
Pulse wave Arterial Stiffness index	0.3	0.4	1.3	-0.1	0.3	-0.2	-0.4	-0.9	-0.6	-1.1
Impedance of arm (left)	0.3	1.2	3.5	1.4	0.6	0.4	0.0	1.9	1.2	-1.1
Hair/balding pattern: Pattern 4	0.3	0.8	1.8	1.1	0.4	0.2	1.4	1.2	0.8	0.6
Pulse wave reflection index	0.3	0.4	1.8	-0.7	0.5	-0.4	-1.3	-0.2	0.1	-0.0
Medication: Amlodipine	0.3	0.4	1.2	-0.4	1.1	0.2	-0.7	-0.4	0.5	0.6
Shortness of breath walking on level ground	0.3	0.4	0.7	-0.9	-0.5	-0.8	-0.7	-0.6	-0.5	-0.1
Neck or shoulder pain in last month	0.3	0.4	0.9	-0.7	-1.0	0.9	-0.4	-0.3	0.5	0.4
Mean time to correctly identify matches	0.3	0.5	1.0	-0.8	0.2	-0.5	-0.5	-0.6	-1.0	-1.0
Pulse rate, automated reading	0.3	0.9	4.9	0.2	-2.2	-0.6	-0.5	-0.2	-0.0	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.0	-0.2	-0.8	0.2	0.5	-0.5	-0.2	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.3	0.0	-0.6	-0.7	-1.1	0.8	0.7	0.9
Mood swings	0.3	0.5	1.3	0.4	1.1	-0.1	0.8	-0.0	-0.4	-1.1
Commuting to job workplace: Walk	0.3	0.3	0.7	0.5	-0.6	0.9	0.6	0.4	0.0	-0.5
Average weekly champagne plus white wine intake	0.3	0.4	1.0	-1.0	0.5	-0.4	-0.8	-0.4	-0.3	-1.0
Commuting to job workplace: Public transport	0.3	0.3	1.2	0.0	-0.9	0.2	-0.1	0.3	-0.2	-1.1
Ever smoked	0.3	0.4	1.5	0.2	1.2	0.1	-0.8	0.5	0.6	-0.4
Number of operations (self-reported)	0.3	0.4	1.2	-0.8	-0.7	0.1	-0.5	0.3	0.6	1.1
Neuroticism (Nagel 2018)	0.2	0.6	1.8	-0.6	0.8	-0.5	0.0	-0.6	-0.7	-1.4
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.7	-0.8	-0.8	-1.3	-0.3	0.1	-0.3	-0.2
Primary Biliary Cirrhosis	0.2	0.3	0.8	0.9	0.2	-0.5	0.3	0.8	0.8	0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.0	0.1	-0.2	0.4	0.3	-0.3	0.0	1.0
Impedance of leg (right)	0.2	1.0	2.3	1.4	-0.5	0.4	0.2	1.4	0.6	-1.5
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	-0.9	0.4	0.1	-0.7	-0.2	-0.3	0.4
Sitting height	0.2	1.2	2.0	-1.4	-0.6	-1.4	-1.2	-1.2	-0.7	0.7
High blood pressure (mother)	0.2	0.2	1.4	-0.2	-0.0	-0.1	0.2	0.0	0.4	1.2
Impedance of leg (left)	0.2	1.2	2.9	1.5	0.0	0.5	0.7	1.3	0.6	-1.7
Past tobacco smoking	0.2	0.4	1.8	-0.1	-1.3	-0.1	0.7	-0.2	-0.4	0.0
Forced vital capacity (FVC)	0.2	0.9	3.3	1.2	-0.1	0.1	0.2	1.8	1.3	0.1
Neuroticism score	0.2	0.4	1.2	-0.3	1.1	-0.7	-0.0	-0.0	0.1	-0.8
Impedance of arm (right)	0.2	1.1	2.6	1.2	0.6	-0.0	-0.1	1.6	1.0	-1.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	3.2	0.5	0.1	-0.1	-0.3	1.8	1.3	-0.2
Pulse rate	0.2	0.4	1.3	0.6	-0.7	-0.3	0.3	-0.3	0.1	-1.2
Happiness	0.2	0.2	0.8	0.1	0.9	-0.3	0.2	0.5	0.5	-0.2
Medication: Lansoprazole	0.2	0.2	0.5	0.1	-0.7	-0.5	0.1	0.7	0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.9	-0.1	-0.3	-0.7	-1.4	1.2	1.0	-0.7
Standing height	0.2	2.4	4.4	-2.1	-1.6	-1.7	-1.9	-1.4	-1.1	0.1
Glaucoma (self-reported)	0.2	0.2	0.6	0.1	-0.6	0.1	-0.8	-0.2	0.2	-0.6
Forced vital capacity (FVC), Best measure	0.2	0.7	2.1	0.7	-0.3	-0.3	-0.8	1.4	1.3	0.1
Number of full brothers	0.2	0.3	0.9	0.8	-0.5	-0.4	0.1	0.0	-0.0	-0.9
Pulse wave peak to peak time	0.2	0.3	1.4	-0.1	-0.2	0.0	0.2	0.6	0.4	1.2
Medication: Allopurinol	0.2	0.3	1.1	1.0	0.4	0.6	0.8	0.3	0.0	-0.0
Heart disease (mother)	0.2	0.3	0.7	0.3	-0.8	-0.4	-0.2	-0.6	-0.9	-0.1
Had major operations	0.2	0.2	0.8	-0.6	-0.9	-0.2	-0.5	-0.4	0.2	0.2
Smoking status: Previous	0.2	0.2	1.2	0.1	1.1	0.6	-0.4	-0.1	0.0	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.8	0.5	0.1	0.2	0.9	0.3	0.0	-0.2
Medication for cholesterol	0.2	0.4	0.5	-0.4	-0.7	-0.7	0.3	-0.7	-0.6	0.7
Smoking status: Current	0.2	0.3	0.9	0.3	0.1	-0.3	0.8	-0.4	-0.6	-1.0
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	0.1	-0.4	0.1	-0.2	-0.9	-0.3	-0.6
Alcohol drinker status: Previous	0.2	0.2	0.6	0.0	-0.2	-0.8	-0.1	-0.3	0.2	-0.8
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	-0.1	-0.7	-0.3	-0.1	0.7	0.5	0.8
Prostate Cancer	0.1	0.2	0.5	-0.2	0.7	0.3	-0.4	0.3	0.3	0.3
Height	0.1	2.4	4.3	-2.1	-2.0	-1.5	-2.0	-1.1	-0.8	-0.0
Qualifications: CSEs or equivalent	0.1	0.2	0.4	-0.2	0.5	-0.3	-0.6	0.4	-0.3	0.2
Hearing difficulty/problems with background noise	0.1	0.2	0.6	0.6	0.4	0.2	-0.3	0.1	0.2	-0.8
Worrier / anxious feelings	0.1	0.2	0.4	-0.4	0.6	-0.6	-0.5	-0.1	0.3	-0.2
Lung cancer (father)	0.1	0.2	0.6	-0.8	-0.2	0.4	-0.4	-0.1	0.3	0.4
Loud music exposure frequency	0.1	0.1	0.2	0.1	-0.4	-0.1	-0.4	-0.1	-0.2	0.2
Alcohol intake frequency.	0.1	0.3	0.7	0.2	-0.6	-0.3	-0.8	0.3	0.5	-0.6
Comparative height size at age 10	0.1	0.8	2.0	-0.2	1.3	-0.9	-0.7	-0.4	0.2	1.4
Smoking Status	0.0	0.1	0.2	0.1	0.3	-0.2	0.3	0.3	-0.1	-0.5
Hair Pigment	0.0	0.9	4.4	-0.5	2.1	-0.8	-0.2	0.1	-0.7	-0.4
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.1	-0.2	0.2	-0.3	-0.2	-0.0	0.1	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	0.1	0.1	0.4	0.2	0.1	0.2	0.3

Hub : Genes

B4GALT3

Models

Trait associations