TWAS hub - RASA3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0500	0.0180	2.1e-04	0.014	0.034	0.036	0.032	0.040	6.7e-03	5.2e-05	2.7e-05	7.6e-05	1.1e-05
2	GTEx	Adipose Subcutaneous	0.1920	0.0450	1.6e-11	0.121	NA	0.142	NA	0.128	4.3e-10	NA	1.1e-11	NA	1.2e-10
3	GTEx	Adipose Visceral Omentum	0.3340	0.0820	3.8e-08	0.132	NA	0.156	NA	0.109	2.4e-07	NA	1.8e-08	NA	2.8e-06
4	GTEx	Brain Cortex	0.2610	0.0910	3.3e-03	0.148	NA	0.106	NA	0.230	7.0e-05	NA	7.5e-04	NA	5.4e-07
5	GTEx	Cells Transformed fibroblasts	0.3120	0.0880	6.4e-03	0.153	NA	0.086	NA	0.121	1.5e-11	NA	5.6e-07	NA	2.2e-09
6	GTEx	Esophagus Mucosa	0.1660	0.0730	4.2e-03	0.066	NA	0.011	NA	0.027	3.5e-05	NA	5.3e-02	NA	6.0e-03
7	GTEx	Esophagus Muscularis	0.1430	0.0610	3.0e-03	0.003	NA	0.021	NA	0.007	1.9e-01	NA	1.8e-02	NA	1.1e-01
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1200	0.0480	3.2e-03	0.105	NA	0.044	NA	0.058	2.3e-06	NA	2.0e-03	NA	4.2e-04
9	GTEx	Skin Sun Exposed Lower leg	0.1500	0.0490	1.8e-05	0.013	NA	0.060	NA	0.044	2.6e-02	NA	1.1e-05	NA	1.4e-04
10	GTEx	Testis	0.4250	0.0730	3.9e-10	0.230	NA	0.301	NA	0.285	1.4e-10	NA	7.8e-14	NA	4.3e-13
11	GTEx	Thyroid	0.2570	0.0470	0.0e+00	0.278	NA	0.295	NA	0.291	1.8e-21	NA	6.5e-23	NA	1.5e-22
12	METSIM	Adipose	0.0603	0.0226	3.9e-05	0.001	0.023	0.018	0.023	0.016	2.2e-01	1.6e-04	8.9e-04	1.7e-04	1.5e-03
13	NTR	Blood	0.0213	0.0102	5.7e-03	0.000	0.003	-0.001	0.004	-0.001	3.1e-01	2.8e-02	5.8e-01	1.5e-02	9.6e-01
14	TCGA	Colon Adenocarcinoma	0.1230	0.0480	6.0e-05	0.092	0.085	0.102	NA	0.104	5.7e-06	1.3e-05	1.8e-06	NA	1.3e-06
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0254	0.0133	4.6e-03	0.002	0.001	-0.001	NA	-0.001	1.8e-01	2.1e-01	5.4e-01	NA	4.6e-01
16	TCGA	Brain Lower Grade Glioma	0.0428	0.0253	2.7e-03	0.010	0.015	0.006	NA	0.007	2.4e-02	7.2e-03	6.3e-02	NA	5.0e-02
17	TCGA	Thyroid Carcinoma	0.0770	0.0310	6.6e-07	0.061	0.060	0.036	NA	0.064	1.4e-06	1.8e-06	1.8e-04	NA	7.1e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Cholesterol lowering medication	8.2	12.0	29.3	3.5	-4.1	-5.4	4.2	-1.3	-0.4	0.4	-3.5	-3.3	4.6	3.7	-4.2	-0.4	-2.9	-4.2	3.1	3.8
High cholesterol (Self-reported)	7.5	13.3	23.6	3.5	-4.2	-4.8	4.9	-1.3	-1.7	-0.4	-4.4	-2.9	4.8	3.8	-4.5	-2.8	-2.8	-4.3	3.0	3.9
Medication: Lisinopril	6.6	8.5	13.5	3.4	-3.2	-3.7	3.5	-1.4	-1.7	-1.2	-3.0	-2.7	3.6	3.1	-3.4	-3.1	-2.4	-3.5	2.0	3.0
Commuting to job workplace: Cycle	5.0	6.1	12.3	-2.5	3.0	2.9	-3.0	0.7	1.3	-0.0	3.1	2.0	-3.0	-3.1	2.1	-0.2	1.5	3.3	-2.4	-3.5
Exposure to tobacco smoke outside home	4.4	5.9	14.9	1.8	-2.5	-1.6	3.9	0.5	0.1	0.4	-3.2	-2.5	2.5	2.9	-2.9	-1.2	-1.6	-2.7	3.1	3.5
Medication: Cholesterol lowering	4.1	6.3	16.8	2.4	-3.1	-2.9	4.1	-0.7	-0.1	-0.3	-3.2	-1.7	2.8	2.8	-2.9	-3.4	-1.1	-2.7	1.7	2.5
Qualifications: None of the above	3.7	7.8	15.7	3.7	-2.8	-3.7	3.2	0.1	0.3	1.2	-2.0	-2.1	3.0	4.0	-3.9	-0.7	-1.1	-3.7	2.7	4.0
Alcohol drinker status: Never	3.6	4.3	12.7	1.2	-2.4	-1.2	0.4	-1.1	-0.8	-1.7	-0.8	-1.1	2.8	2.5	-2.7	1.1	-2.5	-3.0	3.6	2.8
Medication for cholesterol, blood pressure or diabetes	3.5	5.7	19.7	-1.9	2.6	2.6	-3.5	1.3	0.7	1.9	2.6	1.3	-2.8	-2.0	3.4	4.4	0.9	2.4	-1.2	-1.8
Medication: Atorvastatin	3.4	4.2	8.0	2.2	-2.4	-2.3	2.8	0.1	-0.8	0.3	-2.0	-1.6	2.3	2.8	-2.7	-1.0	-1.1	-2.6	2.2	2.5
Medication: Simvastatin	2.9	4.3	9.6	1.8	-2.3	-2.7	3.1	-0.7	-0.5	-0.7	-2.1	-1.7	2.7	2.3	-2.7	-1.7	-1.4	-2.5	1.7	2.2
HbA1C	2.8	3.1	8.5	0.6	-1.9	-1.0	2.3	-0.9	-2.1	-1.7	-0.7	-2.0	2.4	2.0	-2.1	-0.3	0.5	-2.1	1.6	2.9
Diabetes (mother)	2.8	3.5	11.1	2.0	-2.1	-2.1	3.3	0.3	1.4	1.5	-1.8	-1.0	1.9	1.9	-2.5	-2.1	-0.7	-1.6	1.4	2.2
Hypothyroidism (self reported)	2.7	6.3	14.9	0.5	3.2	2.7	-0.4	3.7	0.7	3.2	1.7	3.9	-3.7	-2.7	2.3	-0.6	1.2	2.6	-2.4	-2.3
Age at last live birth	2.7	4.0	7.2	-2.5	2.6	2.0	-2.3	1.3	-0.6	-0.6	2.7	1.9	-2.5	-1.8	2.0	2.1	1.7	2.5	-0.9	-2.0
Medication for cholesterol	2.7	4.0	7.4	-1.7	2.7	2.7	-2.5	0.7	0.4	0.2	2.6	2.2	-2.3	-2.0	2.2	0.7	1.5	2.4	-2.4	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	2.6	2.8	5.7	-2.2	2.3	2.3	-0.5	0.1	0.4	0.3	1.0	1.2	-1.8	-2.4	2.2	1.3	1.2	2.3	-1.5	-2.2
Overall health rating	2.5	5.3	10.4	2.4	-3.1	-1.8	3.2	0.1	0.1	0.6	-2.8	-2.8	2.1	3.0	-2.3	-1.9	-0.0	-2.4	2.5	3.2
Hypertension (Self-reported)	2.5	7.0	18.7	1.9	-3.4	-2.4	3.9	-1.3	1.7	-1.2	-3.9	-2.6	2.9	2.1	-3.2	-4.3	-0.8	-2.5	1.7	1.9
Number of self-reported non-cancer illnesses	2.5	4.3	9.8	1.9	-2.8	-2.1	2.6	-0.6	-0.1	-0.2	-1.9	-2.2	2.7	1.8	-3.1	-1.3	-2.1	-2.6	2.0	1.9
Heart disease (siblings)	2.5	3.0	8.6	2.9	-1.4	-2.8	1.2	-0.4	-0.1	-0.7	-0.8	-1.3	2.0	2.5	-1.9	0.6	-1.2	-2.9	1.1	2.0
Alzheimer’s Disease (including proxy)	2.4	3.5	10.2	1.6	-2.4	-1.1	1.4	0.7	1.1	1.2	-1.1	-1.4	1.2	3.1	-2.5	-0.8	0.1	-2.0	3.0	3.2
Mouth/teeth dental problems: Dentures	2.4	4.1	11.4	0.7	-1.6	-1.4	3.4	1.9	1.2	2.3	-2.6	-1.2	0.8	2.6	-2.1	-0.8	-0.0	-1.1	3.3	3.2
Commuting to job workplace: Car/motor vehicle	2.4	2.7	5.5	1.6	-2.0	-1.5	2.3	-0.1	-1.0	-0.1	-1.7	-0.6	1.8	2.0	-1.9	-2.3	-1.0	-1.5	1.9	2.2
Vascular/heart problems diagnosed by doctor	2.4	6.6	16.5	-2.2	3.6	2.7	-3.7	1.1	-1.8	0.6	3.5	2.4	-2.7	-2.1	3.2	4.1	1.0	2.4	-1.5	-1.8
Lung cancer (father)	2.3	2.6	8.8	-0.6	1.3	2.2	-0.6	1.5	1.8	3.0	1.2	2.0	-1.8	-1.7	0.9	-1.2	0.1	2.3	-1.3	-1.4
Guilty feelings	2.3	3.4	8.8	-2.0	1.7	1.9	-2.2	-1.3	0.7	0.1	1.2	1.3	-1.5	-2.5	1.5	0.5	1.7	2.3	-2.9	-3.0
Pulse rate, automated reading	2.2	7.1	18.4	1.1	-4.3	-3.3	3.1	-1.3	-2.2	-1.1	-3.5	-2.5	3.3	2.8	-2.1	-0.9	-2.0	-3.2	2.8	3.1
Medication: Aspirin	2.2	2.9	5.6	2.1	-2.2	-2.0	2.0	-0.9	0.5	-0.9	-2.4	-1.2	2.0	1.6	-2.2	-1.5	-1.6	-2.1	1.0	1.5
Long-standing illness, disability or infirmity	2.2	3.4	8.3	1.9	-2.4	-1.7	2.9	0.8	0.8	2.5	-2.4	-1.5	1.1	2.2	-1.8	-1.3	-0.4	-1.7	1.7	2.1
Medication: Blood pressure	2.2	4.2	12.8	1.2	-2.5	-1.8	3.1	-0.6	1.0	-0.1	-3.6	-2.8	2.2	2.0	-1.8	-0.4	-1.2	-2.3	2.4	2.2
Hair/balding pattern: Pattern 2	2.1	2.6	6.6	2.6	-2.1	-1.7	2.4	0.4	1.1	1.7	-1.3	-1.7	0.9	2.5	-0.7	-0.7	0.5	-1.5	1.3	2.0
Blood Eosinophil Count	2.0	15.3	39.6	6.3	-3.2	-4.5	2.8	-0.4	0.2	1.2	-1.8	-4.6	3.8	6.2	-4.4	2.1	0.6	-6.1	3.0	5.8
Cardiovascular Disease	2.0	6.5	24.8	1.5	-3.2	-2.7	3.6	-1.6	1.5	-1.4	-3.7	-2.3	2.9	1.4	-3.2	-5.0	-0.6	-2.1	1.1	1.1
Number of treatments/medications taken	2.0	3.6	8.8	1.9	-2.5	-2.2	2.3	0.2	-0.4	0.8	-1.9	-1.5	1.6	2.1	-3.0	-2.7	-0.7	-2.0	1.6	2.0
High blood pressure	2.0	5.5	17.4	1.9	-3.0	-2.1	3.5	-0.8	1.6	-1.0	-3.5	-2.0	2.4	1.6	-3.0	-4.2	-0.9	-2.1	1.3	1.5
Medication: Ramipril	2.0	2.5	7.1	2.3	-0.8	-1.2	1.8	-0.9	-0.1	-1.4	-1.6	-1.6	2.1	2.2	-1.6	-0.9	-0.3	-2.7	0.9	1.9
Fluid intelligence score	2.0	4.2	11.4	-2.5	2.6	3.4	-1.6	0.4	0.7	-0.1	1.5	2.1	-2.2	-2.8	2.4	1.2	0.5	2.6	-1.8	-2.7
Medication for pain relief, constipation, heartburn	2.0	3.5	12.6	-2.0	2.4	1.9	-1.3	0.3	0.4	-0.3	2.0	1.3	-1.7	-2.3	3.5	2.5	0.9	1.9	-1.7	-2.0
Number of full sisters	1.9	2.3	7.7	1.1	-1.4	-1.0	0.8	-1.0	-0.8	-1.8	-1.5	-0.9	1.9	0.8	-2.8	-0.7	-2.5	-1.7	1.3	1.4
Alzheimer’s Disease (in father)	1.8	2.0	5.7	0.3	-2.0	-0.8	0.1	-0.9	1.3	0.1	0.3	-1.3	1.7	2.4	-1.5	-0.0	-0.4	-1.6	2.4	2.3
Angina	1.8	2.3	6.1	2.1	-0.8	-1.4	2.5	0.8	2.3	1.6	-1.0	-1.2	0.8	2.4	-1.1	-1.0	1.2	-1.6	0.8	1.5
Medication: Lansoprazole	1.8	2.1	5.2	2.3	-1.1	-1.9	1.2	-0.8	-1.3	-0.1	-1.7	-2.0	1.6	1.4	-1.5	0.1	-0.6	-1.9	1.2	1.6
Schizophrenia (2018)	1.7	3.5	14.0	3.7	-1.0	-1.7	1.7	1.9	0.1	2.4	-0.5	-0.6	0.8	2.4	-2.1	0.4	-1.0	-2.4	2.0	2.5
Illness, injury, bereavement, stress in last 2 years	1.7	2.0	6.0	0.5	-1.3	-0.0	1.7	-0.7	-1.4	-2.4	-1.9	-1.7	1.8	1.1	-0.3	0.5	-1.6	-1.8	1.6	1.4
Primary Biliary Cirrhosis	1.6	2.3	9.2	1.0	-2.0	-1.1	1.8	-0.9	-0.3	-0.2	-1.1	-3.0	1.6	2.1	-1.0	0.8	0.6	-1.7	1.6	2.0
Medication: Atenolol	1.6	2.0	5.0	1.2	-1.1	-1.7	1.8	0.3	1.2	1.3	-1.8	-1.4	1.2	2.2	-1.4	-0.6	0.2	-1.7	1.1	1.8
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	6.1	-0.3	1.9	0.8	-1.9	-0.5	1.2	0.8	2.2	-0.3	-1.1	-1.1	1.7	0.1	2.0	1.3	-2.5	-1.8
Illnesses of siblings	1.6	2.2	6.7	-1.8	1.5	1.3	-0.8	1.2	-0.6	1.7	1.1	1.1	-2.1	-1.1	2.6	0.7	1.8	2.4	-0.6	-0.9
Medication: Amlodipine	1.6	2.2	6.5	1.1	-1.1	-0.8	2.3	-0.2	-0.7	-1.1	-2.4	-0.5	1.5	0.5	-2.6	-2.1	-1.7	-1.4	1.4	1.2
Number of full brothers	1.6	2.0	5.8	-0.7	1.9	1.8	-2.4	-0.6	-1.2	-1.5	1.3	1.4	-1.2	-1.8	1.0	0.2	0.8	1.0	-1.9	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	4.1	-0.8	1.0	0.8	-0.7	0.4	0.5	1.4	1.9	1.4	-1.6	-1.4	1.0	-1.9	1.4	2.0	-1.8	-1.8
Medication: Blood pressure	1.6	2.8	20.4	1.0	-1.2	-1.0	2.1	-1.3	-0.1	-2.4	-2.0	-0.7	1.5	0.4	-2.1	-4.5	-0.6	-1.0	-0.0	0.2
Angina (self-reported)	1.6	2.1	5.5	2.1	-0.9	-1.5	2.2	0.4	2.3	1.4	-1.1	-1.3	0.9	2.3	-1.0	-0.8	1.0	-1.6	0.7	1.4
Had major operations	1.6	1.8	5.0	-2.2	1.8	1.2	-1.4	-0.6	-2.0	-1.4	1.4	1.9	-0.2	-1.5	0.7	-0.2	-0.2	1.4	-0.8	-1.4
Average weekly champagne plus white wine intake	1.6	2.2	8.3	-2.0	1.2	2.9	-1.5	1.1	0.3	-0.1	1.8	2.1	-1.5	-1.0	1.8	-0.6	1.1	1.7	-0.3	-1.1
Diastolic blood pressure, automated reading	1.6	5.0	24.4	1.9	-2.9	-2.5	2.1	-1.5	3.0	-0.9	-2.9	-2.0	2.0	1.3	-2.0	-4.9	-0.2	-1.5	-0.2	1.0
Basal cell carcinoma (self-reported)	1.6	1.9	8.2	-0.7	-1.5	-0.4	-1.6	-2.9	-2.6	-2.1	-0.0	-1.8	1.2	-0.4	-0.3	1.3	-0.4	-0.3	-0.2	-0.2
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	7.7	1.4	-0.9	-1.4	2.8	0.7	-1.7	0.8	-2.0	-0.7	1.2	1.3	-0.8	0.3	-0.9	-1.5	1.6	1.6
Alcohol usually taken with meals	1.5	2.4	11.7	-0.8	2.1	1.5	-0.6	1.7	1.3	0.7	1.0	1.9	-2.1	-1.0	3.4	0.4	1.6	1.2	-1.1	-1.2
Chronic bronchitis/emphysema (mother)	1.5	1.7	9.4	-0.3	1.1	1.1	-0.3	1.6	1.4	3.1	1.1	1.4	-1.5	-0.7	1.5	0.2	1.1	1.2	-0.7	-0.7
Worry too long after embarrassment	1.5	2.5	5.9	-2.3	1.6	1.6	-1.3	-0.8	0.9	-1.1	0.6	0.1	-1.4	-2.4	1.7	1.6	0.7	2.0	-2.2	-2.4
Ever smoked	1.5	2.7	5.7	-0.3	2.0	2.2	1.1	2.1	-0.4	0.7	-0.0	1.5	-2.4	-2.1	2.2	-1.0	1.6	2.1	-1.4	-1.6
Crohns Disease (2012)	1.4	2.3	7.0	1.1	-2.4	-0.8	1.2	-1.8	0.1	-0.1	-1.8	-1.4	2.1	1.3	-1.9	-2.7	-0.8	-1.4	0.5	1.2
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	4.3	1.4	1.0	-1.4	1.0	1.9	0.1	1.7	-0.5	0.4	0.2	1.7	-0.5	2.1	-0.3	-1.2	1.6	1.9
Pain all over the body in last month	1.4	1.5	6.0	2.1	0.4	-0.1	1.8	1.3	-0.8	1.1	1.7	-0.3	0.3	1.2	-0.1	0.0	2.5	-1.0	0.6	1.7
Length of working week for main job	1.4	1.5	4.5	-1.6	1.0	1.0	-2.1	-0.6	-0.0	0.4	1.6	1.1	-1.0	-1.2	1.1	1.5	1.0	1.4	-1.6	-1.1
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	4.6	-0.6	1.6	1.9	-1.7	0.7	0.1	-0.0	0.9	1.5	-2.0	-2.2	1.9	0.4	0.7	1.9	-1.8	-2.0
Emphysema/chronic bronchitis	1.4	1.6	5.6	0.2	-1.8	-1.5	1.0	-1.7	1.1	0.1	-1.3	-2.4	1.4	1.0	-1.2	1.4	-0.5	-1.2	0.9	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	9.2	0.6	-0.5	-1.1	0.2	-1.8	-0.7	-3.0	-1.7	-0.7	1.6	0.1	-1.5	-1.3	-1.7	-1.2	-0.1	0.3
Illnesses of father: None of the above (group 1)	1.4	1.7	7.6	-0.2	1.3	0.3	-0.3	1.6	0.3	2.8	-0.1	0.7	-1.9	-1.3	2.2	1.3	0.6	1.8	-0.8	-0.7
Intelligence (Savage-Jansen 2018)	1.3	4.1	10.5	-3.2	2.8	2.7	-1.5	0.6	0.1	-0.0	0.9	1.8	-2.2	-2.9	2.3	0.6	0.5	3.0	-1.7	-2.5
Blood White Count	1.3	9.8	41.5	0.3	-4.0	-3.8	2.9	1.7	-0.7	-1.3	-1.9	-1.3	2.7	5.1	-1.0	0.7	-0.5	-3.9	6.4	5.0
Waist Hip Ratio (WHR)	1.3	5.8	12.4	2.1	-2.5	-0.7	3.4	-0.9	-2.4	-1.0	-1.8	-2.9	2.7	3.5	-2.3	-2.3	1.0	-2.7	2.7	3.3
Ever used hormone-replacement therapy (HRT)	1.3	1.7	4.7	0.9	-1.8	-1.7	0.5	-1.3	-0.1	-0.7	0.6	-1.2	2.0	1.9	-1.0	0.8	-0.1	-2.2	0.9	1.5
Qualifications: CSEs or equivalent	1.3	1.7	4.5	0.2	1.6	1.1	-2.1	-0.1	0.9	-0.3	1.3	1.3	-1.5	-1.0	1.4	-1.0	1.8	0.9	-2.0	-1.6
Tense / ‘highly strung’	1.3	2.2	6.6	-1.7	1.0	0.1	-2.0	-1.9	1.5	-0.8	1.3	0.4	-0.5	-2.0	0.7	0.9	0.8	1.7	-2.6	-2.2
Shortness of breath walking on level ground	1.3	1.5	4.0	1.7	-1.3	-1.0	2.0	0.1	1.0	0.8	-0.9	-1.9	0.9	1.3	-1.3	-0.4	-0.2	-1.2	1.6	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	5.7	1.6	-0.8	-0.5	2.1	0.3	-0.2	-0.0	-2.4	-1.3	0.9	1.1	-0.9	-1.2	-0.2	-1.5	1.6	1.6
Medication: Aspirin	1.3	1.7	4.1	1.8	-1.5	-1.5	1.4	-1.1	-0.0	-1.1	-1.9	-0.9	1.4	0.5	-1.8	-2.0	-1.0	-1.3	-0.1	0.7
Schizophrenia (2014)	1.2	2.6	11.5	3.4	0.2	-0.9	1.7	2.4	-0.1	2.6	-0.1	0.4	0.2	2.1	-1.6	0.2	-0.1	-1.9	1.2	2.0
Systolic Blood Pressure	1.2	6.0	32.5	0.4	-0.8	0.1	1.4	-3.1	-1.4	-5.7	-3.1	-2.0	2.0	-0.7	-2.0	-5.6	-0.5	-0.9	-0.9	-0.3
Systolic blood pressure, automated reading	1.2	3.4	16.7	0.8	-2.0	-0.9	1.7	-1.7	-0.1	-2.9	-2.6	-1.6	1.8	0.6	-2.3	-4.1	-0.9	-1.2	0.1	0.8
Medication: Co-codamol	1.2	1.4	3.9	0.9	-0.2	-1.6	1.4	0.6	0.2	0.5	-0.8	-0.6	1.0	1.6	-0.8	1.9	0.0	-1.4	2.0	2.0
Multivitamins +/- minerals	1.2	1.6	4.5	-0.1	1.7	1.3	-0.8	1.2	0.8	1.6	1.4	1.1	-2.1	-1.2	0.7	-0.2	1.7	1.7	-1.0	-0.7
Medication: Levothyroxine sodium	1.2	2.0	4.8	-0.2	1.3	1.6	-0.5	1.1	-0.1	0.9	0.7	1.7	-1.7	-2.1	1.3	-2.0	0.5	1.7	-2.2	-1.8
Pulse rate	1.2	2.0	5.3	0.3	-2.1	-0.7	2.3	1.1	-1.7	0.4	-0.1	0.3	1.1	1.9	-1.8	-0.7	-0.7	-1.0	2.3	2.2
Exposure to tobacco smoke at home	1.2	1.4	3.6	0.3	-1.4	-0.2	1.5	-0.0	-0.7	-1.0	-0.6	-0.2	1.5	1.4	-1.7	-0.2	-1.0	-1.3	1.9	1.9
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	6.4	0.1	1.4	1.3	-0.4	1.7	-0.1	1.2	1.4	2.5	-1.9	-1.9	1.6	-1.5	0.4	1.7	-2.1	-1.7
Diabetes diagnosed by doctor	1.2	1.9	5.5	1.3	-1.4	-1.5	2.3	2.0	0.9	2.2	-0.8	-0.2	0.2	1.6	-0.7	0.4	-0.3	-1.1	1.7	1.7
Back pain experienced in last month	1.2	1.8	4.5	1.5	-2.0	-1.5	0.8	-0.6	0.5	0.3	-2.1	-1.3	1.6	1.2	-0.9	0.6	-1.7	-1.7	1.4	1.4
Osteoporosis (self-reported)	1.2	1.5	6.5	-1.4	-1.5	-0.7	-0.6	-2.6	0.1	-1.0	-0.2	-1.6	1.5	0.6	-0.8	1.2	-1.6	-0.3	1.6	0.1
Illnesses of father: High blood pressure	1.2	1.5	8.9	-0.8	-0.9	1.1	-0.2	-1.1	3.0	-1.0	-0.7	0.7	0.2	-0.8	-0.6	-2.7	-1.0	0.5	-0.3	-0.9
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	9.0	0.7	-0.6	-0.5	3.0	-0.9	-0.1	0.2	-0.8	-2.5	1.2	1.1	-0.3	-1.2	2.0	-0.7	-0.4	0.8
Bipolar Disorder or Schizophrenia	1.1	2.8	10.6	3.3	-1.1	-1.5	1.3	1.8	-0.8	1.7	0.7	-0.1	0.7	2.3	-2.3	-0.1	-0.0	-1.9	1.8	2.4
Crohns Disease (2017)	1.1	2.3	6.3	0.7	-2.5	-1.2	1.5	-0.5	0.5	0.4	-1.6	-0.9	1.9	1.6	-2.2	-0.8	-2.0	-1.6	2.1	1.6
Irritable Bowel Disease (IBD)	1.1	2.5	8.1	0.6	-2.0	-1.1	2.4	0.3	0.6	0.8	-2.1	-1.4	1.7	1.7	-1.3	-0.0	-1.6	-1.6	2.8	1.9
Coronary Artery Disease (CAD)	1.1	1.3	4.4	0.5	0.0	-0.2	1.1	0.0	0.2	-0.7	-2.0	-1.6	1.7	0.7	-0.8	-1.1	-2.1	-0.9	1.8	0.7
Sensitivity / hurt feelings	1.1	1.9	5.2	-1.7	1.8	0.4	-1.3	-1.8	-0.8	-2.3	0.8	-0.1	-0.3	-1.8	1.1	1.5	0.8	1.0	-1.9	-1.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	3.0	1.4	-1.2	-1.2	1.6	0.2	0.5	1.1	-1.7	-0.7	0.9	1.0	-0.8	-1.4	-0.7	-0.9	0.9	1.1
Hayfever, allergic rhinitis or eczema	1.1	2.4	10.0	-1.2	1.9	1.6	-3.2	-0.3	0.4	0.1	1.9	0.0	-1.7	-1.1	1.6	1.3	1.7	1.2	-2.0	-1.6
Stomach or abdominal pain in last month	1.1	1.3	3.2	1.7	-1.0	-1.2	-0.1	-1.8	0.7	1.1	-1.6	-1.2	1.4	0.7	-1.8	-0.3	-0.7	-0.7	-1.1	0.3
Diabetes (self-reported)	1.1	1.7	5.2	1.0	-1.5	-1.6	2.2	1.6	0.9	2.3	-1.2	-0.1	0.3	1.4	-0.6	0.2	-0.6	-0.9	1.8	1.5
Family relationship satisfaction	1.1	1.4	7.1	0.7	-0.9	0.3	0.7	-0.3	-1.5	-0.8	-2.7	-0.8	1.0	-0.1	-2.1	-0.9	-1.9	-0.7	0.7	0.6
Age started oral contraceptive pill	1.1	1.4	3.6	0.5	-1.4	-1.8	1.3	-0.2	0.3	-0.3	-0.3	-1.5	1.6	1.8	-0.5	0.9	-0.3	-1.9	1.1	1.5
Myopia	1.1	1.6	3.8	-0.9	1.4	1.6	-1.5	-0.1	0.2	-0.1	1.1	0.8	-1.4	-1.6	1.7	0.6	0.3	1.6	-1.9	-1.8
Supplements: Calcium	1.1	1.2	2.6	-1.4	1.1	1.6	-0.6	0.4	0.5	0.2	0.5	1.0	-1.2	-1.6	1.6	1.2	-0.3	1.4	-0.6	-1.4
Schizophrenia vs Biploar Disorder	1.0	1.3	3.4	1.8	-0.6	-0.5	1.2	1.0	0.3	1.2	-1.3	0.5	0.6	1.2	-0.7	0.5	-1.7	-1.2	1.8	1.2
Breast Cancer	1.0	2.5	7.8	-1.0	0.9	-0.4	-2.8	1.1	1.8	1.2	2.8	2.6	-1.9	-0.4	1.2	1.6	0.3	0.8	-1.5	-1.1
Average weekly spirits intake	1.0	1.2	3.4	1.2	-1.8	-0.7	1.8	-0.3	0.4	-0.3	-1.5	-1.2	1.2	1.1	-1.3	-1.2	-0.5	-1.1	0.5	0.8
Medication: Metformin	1.0	1.5	4.9	1.0	-1.3	-0.8	1.6	1.4	-0.1	0.5	-1.1	-0.2	0.7	1.7	-1.0	0.0	-0.9	-1.3	2.2	1.8
Diabetes (father)	1.0	1.2	3.3	1.5	-1.0	-1.8	0.6	-0.3	-0.5	0.2	-1.4	-0.7	1.1	1.2	-1.4	0.1	-0.9	-1.8	1.0	1.1
Relative age voice broke	1.0	1.5	5.0	0.2	-1.6	-1.3	0.7	-0.1	-0.4	-2.2	-0.5	-1.0	1.3	1.5	-0.4	0.3	-0.4	-1.7	1.9	1.9
Chronic bronchitis/emphysema (father)	1.0	1.2	3.0	1.2	-0.3	-0.8	1.7	1.0	0.5	0.3	-0.9	-0.9	0.7	1.1	-0.9	1.6	-0.7	-1.5	1.6	1.1
Financial difficulties in last 2 years	1.0	1.3	5.4	0.6	0.5	-0.1	-0.1	0.4	2.0	2.0	1.2	-0.4	-1.2	-0.5	-0.1	-0.9	2.3	1.1	-1.4	-0.9
Happiness	1.0	1.2	4.4	-0.4	-0.3	1.2	-1.2	-1.7	-1.6	-2.1	-1.1	-0.7	0.4	-1.5	-0.7	-0.9	-1.1	0.5	-0.2	-1.0
Qualifications: A levels/AS levels or equivalent	1.0	2.2	6.3	-1.9	0.6	2.1	-1.5	0.2	-0.2	0.5	0.1	1.3	-1.5	-2.5	1.8	0.3	-0.9	2.1	-1.5	-2.3
Blood clot in the leg (DVT)	1.0	1.3	6.0	0.8	-0.1	-0.2	2.5	-0.6	-0.4	0.2	-0.6	-2.2	0.9	1.0	-0.1	-1.2	2.2	-0.7	-0.5	0.6
Medication: Paracetamol	1.0	1.6	7.6	1.9	-0.5	-0.4	0.3	0.3	-0.9	0.9	-0.8	-1.0	0.8	1.8	-2.7	-1.2	0.2	-1.3	1.4	1.8
Neck or shoulder pain in last month	1.0	1.4	6.1	2.5	-1.0	-1.9	1.5	-0.5	0.6	0.5	-0.8	-1.4	1.1	0.9	-0.6	-1.2	0.1	-1.5	-0.6	0.7
Loneliness, isolation	1.0	1.4	4.2	0.4	-1.8	-1.9	0.4	-2.0	0.6	-1.2	-0.8	-1.2	1.6	0.4	-1.5	-1.0	-0.9	-1.1	-0.2	0.3
Eye problems/disorders: Cataract	1.0	1.2	3.5	-0.7	0.3	-0.6	0.0	0.5	1.9	1.8	1.2	1.0	-1.1	-0.5	1.1	-1.0	1.3	1.4	-1.3	-1.1
Asthma (self-reported)	1.0	1.9	6.9	1.3	-0.8	-1.2	1.7	0.8	-1.2	0.6	-0.9	-2.6	0.8	1.9	-1.2	0.9	0.5	-1.5	1.9	1.8
Supplements: Fish oil (including cod liver oil)	1.0	1.3	4.0	-0.0	-1.0	-1.5	0.9	-0.4	-0.6	-1.2	-1.0	-1.1	1.2	1.2	-0.9	1.4	-1.2	-1.3	2.0	1.4
Pain experienced in last month	1.0	1.7	6.3	-2.5	1.6	1.7	-0.6	0.8	-0.3	-1.3	0.4	2.3	-1.2	-1.0	1.6	0.6	-0.3	1.3	0.5	-1.0
Alzheimer’s Disease (in mother)	0.9	1.1	3.0	1.3	-1.0	-0.3	0.9	1.2	0.9	1.3	-0.4	-0.4	-0.1	1.3	-1.7	-1.5	0.9	-0.6	0.8	1.4
Age at First Birth	0.9	1.3	8.8	-2.2	0.1	-0.0	0.0	0.9	-1.4	-1.0	0.2	-0.4	-0.1	0.9	0.3	3.0	0.8	0.0	1.7	0.8
Triglycerides	0.9	1.4	7.1	1.7	-0.4	-0.5	2.7	1.1	-1.8	1.0	-1.0	-0.3	0.9	1.3	-0.7	-0.6	0.4	-0.9	0.6	1.5
Ulcerative Colitis	0.9	1.3	4.8	0.5	-0.9	-0.3	2.2	0.1	-0.7	-1.1	-1.3	-1.5	1.2	1.3	0.7	0.3	0.5	-1.3	1.7	1.5
Ever had hysterectomy (womb removed)	0.9	1.0	3.8	0.5	-0.2	-0.8	1.3	0.9	-1.0	0.9	-0.7	-0.9	0.6	1.2	-0.6	1.5	-0.1	-0.8	2.0	1.5
Past tobacco smoking	0.9	1.6	7.1	-0.4	-1.2	-0.8	-2.0	-2.7	0.1	-1.1	0.4	-0.7	1.9	1.0	-1.3	0.5	-1.9	-1.2	0.4	0.4
Falls in the last year	0.9	1.2	6.4	0.4	-1.4	-1.8	-0.1	-1.2	-0.7	-0.6	0.2	-1.0	1.5	1.2	-2.5	-0.2	0.2	-1.1	0.3	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	8.8	1.1	-1.4	-0.3	0.7	-0.7	-0.8	-0.2	-0.8	-1.0	0.9	0.7	-1.1	-3.0	0.2	-0.5	-0.6	0.2
Breastfed as a baby	0.9	1.1	5.5	-2.4	-0.4	1.3	-0.9	0.1	-1.0	-0.9	0.6	1.1	-0.2	-0.6	-0.0	1.4	-1.2	0.4	1.7	-0.2
Headache pain in last month	0.9	1.6	6.2	2.4	-1.5	-0.9	0.2	-0.9	0.7	0.6	-0.3	-1.3	1.0	0.9	-2.5	-2.1	-0.6	-0.9	-0.6	0.7
Chest pain or discomfort	0.9	1.3	3.0	1.4	-1.6	-1.3	1.7	-0.0	0.2	-0.0	-1.3	-0.8	1.4	1.0	-1.2	-0.9	-1.5	-1.3	1.0	0.8
Ever taken oral contraceptive pill	0.9	1.0	3.7	-0.4	1.0	1.2	1.2	1.5	1.0	0.3	0.7	0.2	-1.1	-0.3	1.7	0.2	1.9	0.7	-0.5	-0.5
Prostate Cancer	0.8	1.2	3.7	1.9	0.1	-1.1	1.4	0.5	-1.6	-0.4	-1.3	-0.4	1.1	0.9	-0.6	0.6	-0.7	-1.6	0.4	1.3
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.0	1.3	-0.9	-1.2	-0.1	0.0	1.7	0.4	-0.1	-0.5	0.7	1.7	-0.3	0.1	0.3	-1.5	0.6	1.3
Average weekly fortified wine intake	0.8	1.0	3.3	0.1	1.4	0.5	-1.0	-0.8	-0.8	-1.6	0.2	-0.1	-0.5	-1.1	1.1	-0.2	0.5	0.7	-1.8	-1.7
Age when periods started (menarche)	0.8	1.9	10.8	-1.3	-1.7	0.4	-0.3	-1.5	-0.8	-2.5	-1.2	0.3	0.9	-0.5	-1.3	-3.3	-1.6	-0.1	0.3	-0.1
Forced vital capacity (FVC)	0.8	3.0	12.4	-2.6	0.7	1.8	-1.0	0.6	1.8	2.2	2.1	0.5	-1.4	-0.4	3.5	2.6	1.1	1.6	-0.8	-1.3
Mouth/teeth dental problems	0.8	1.2	4.7	-0.7	0.5	0.5	-1.6	-1.1	-0.5	-1.8	2.2	1.0	0.0	-1.0	1.0	-0.5	0.0	0.4	-1.5	-1.5
Hair/balding pattern: Pattern 4	0.8	1.9	4.7	-0.6	1.6	2.2	-0.6	1.8	0.8	2.2	-0.3	2.1	-2.0	-1.4	0.3	-0.7	-0.7	1.7	-0.3	-1.4
Glaucoma (self-reported)	0.8	1.0	4.1	-0.1	1.3	1.0	-0.7	1.3	-0.1	0.6	2.0	0.6	-1.4	-0.8	0.4	0.1	1.4	0.9	-0.8	-0.7
Migraine (self-reported)	0.8	1.0	2.8	1.2	-1.1	-0.6	1.2	0.1	-0.2	-0.4	0.3	-1.4	1.3	1.4	-0.9	-0.2	0.1	-1.7	0.9	1.3
Mean time to correctly identify matches	0.8	1.6	5.7	1.2	0.1	-1.1	1.3	1.1	-1.2	0.2	-0.1	0.3	1.1	1.8	-1.3	0.4	-0.7	-1.7	2.2	2.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	3.7	-0.4	0.4	-0.7	1.0	1.6	1.3	1.9	-1.6	0.1	-0.6	1.0	0.1	0.6	0.3	-0.1	1.4	0.6
Breast cancer (self-reported)	0.8	0.9	5.5	-0.6	0.8	2.3	-0.9	0.8	-0.8	0.1	-0.2	0.9	-1.3	-1.3	0.8	-0.4	-0.2	1.2	0.5	-0.7
Ulcerative Colitis (UC)	0.7	1.3	6.6	0.0	-0.7	-0.1	2.1	1.1	-0.2	0.7	-1.5	-1.0	0.8	0.9	-0.2	0.8	-0.9	-0.8	2.6	1.5
LDL Cholesterol	0.7	1.1	5.2	1.9	-1.5	-1.2	1.6	-0.4	-0.1	0.0	-1.1	-0.7	0.9	0.6	-0.2	-2.3	0.3	-0.9	-0.4	0.1
Blood Red Count	0.7	6.7	50.1	-0.2	-2.8	0.0	1.1	-3.5	-4.1	-2.4	-0.8	-1.8	2.9	-0.2	-2.7	-7.1	-0.1	0.1	-1.0	-0.3
Chronotype (morning person)	0.7	1.6	5.4	-0.6	1.0	1.1	-1.0	1.2	-1.6	-1.0	-0.4	1.8	-0.3	-0.3	0.5	2.1	-2.3	-0.1	2.1	0.8
Hearing difficulty/problems: Yes	0.7	1.1	4.1	0.9	-0.4	-1.1	0.8	-1.5	-0.6	-1.4	-1.0	-0.6	2.0	0.8	-1.2	-0.4	-1.3	-1.5	0.0	0.7
Relative age of first facial hair	0.7	1.5	6.3	0.5	-0.9	-0.5	0.3	-0.7	0.1	-2.5	-1.4	-1.6	1.4	1.4	-0.4	0.3	-0.3	-1.8	1.7	1.6
Vitamin and mineral supplements	0.7	0.9	5.4	-0.3	-0.8	-0.4	0.7	-0.6	-1.5	-2.3	-0.5	-0.6	1.4	0.5	-0.6	-0.4	-1.0	-1.2	0.4	0.6
Supplements: Zinc	0.7	0.8	4.7	0.2	-1.2	-0.1	0.2	-1.8	0.0	-0.4	-1.5	-2.2	0.4	-0.7	-0.6	0.2	-0.4	0.2	-0.7	-0.6
Severe depression (siblings)	0.7	0.8	3.3	-1.4	0.7	0.3	-0.8	-0.1	-0.2	-0.1	-0.0	0.5	-0.9	-1.8	0.7	1.1	-0.4	1.2	-0.8	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	3.0	-1.3	0.6	0.6	-1.5	-1.2	-0.1	-0.9	1.7	0.4	-0.1	-0.8	0.4	-0.4	0.7	0.8	-1.6	-1.3
Serious illness, injury or assault to yourself	0.7	0.8	2.7	1.3	-0.6	-1.4	0.0	0.8	-0.4	1.6	-0.9	-0.2	-0.0	1.0	-1.0	0.4	-0.7	-0.7	1.2	0.8
Number of incorrect matches in round	0.7	1.2	3.7	-0.3	0.3	1.4	-0.5	0.1	-1.9	0.5	1.5	0.4	-0.7	-0.8	-0.5	-1.9	1.6	1.3	-1.2	-0.7
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	10.8	-1.9	1.0	1.0	-1.0	0.7	1.2	2.3	2.0	0.8	-1.3	-0.1	3.3	2.6	0.9	1.3	-0.9	-1.0
Noisy workplace	0.7	0.8	2.1	0.9	1.1	-0.0	-0.6	0.5	0.7	1.4	1.4	0.9	-1.0	-0.3	-0.6	-0.5	1.3	0.5	-1.5	-0.9
Asthma	0.7	1.4	5.0	1.2	-0.5	-0.9	1.4	0.9	-1.1	0.6	-0.6	-2.2	0.5	1.6	-0.8	0.8	0.7	-1.2	1.6	1.6
Illnesses of mother	0.7	0.9	5.8	-0.6	0.5	0.3	-2.0	0.1	0.7	-0.1	0.5	0.5	-1.2	-0.5	1.1	2.4	-0.5	0.4	-0.2	-0.9
High blood pressure (siblings)	0.7	1.0	4.1	1.0	-1.1	-0.0	0.9	-0.6	0.7	-1.2	-1.4	-0.7	1.0	0.2	-1.4	-2.0	-0.9	-1.1	0.4	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.6	-0.3	1.1	1.3	-1.1	0.0	0.0	0.2	0.5	0.4	-1.1	-1.6	1.2	0.0	0.6	1.1	-1.3	-1.4
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.1	-0.2	1.4	0.9	-0.9	0.9	-0.3	-0.9	0.1	0.8	-1.4	-1.5	1.0	0.2	-0.2	0.9	-0.4	-1.1
Alcohol intake frequency.	0.7	1.7	5.8	0.8	-0.7	-1.4	1.2	0.1	-0.1	0.2	-0.1	-1.0	1.8	1.9	-1.2	1.2	-0.7	-1.9	2.4	2.1
Smoking status: Previous	0.7	1.1	6.4	0.5	0.8	-0.2	2.1	2.5	-0.4	1.0	-0.4	0.5	-1.4	-0.4	0.3	0.3	1.3	0.4	0.4	0.4
Qualifications: nursing, teaching	0.7	1.1	3.8	-1.7	0.5	0.7	-1.2	0.0	-0.4	-0.3	0.4	0.1	-1.3	-1.8	0.7	0.0	0.5	1.7	-1.1	-1.9
Osteoarthritis (self-reported)	0.7	0.9	2.0	-1.4	1.4	0.6	-1.2	0.2	1.4	-0.2	0.2	0.6	-1.0	-1.3	0.9	1.3	-0.2	0.9	-0.7	-1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.8	0.5	0.4	-0.4	0.1	-0.9	-0.8	-2.0	0.3	-1.1	0.4	-0.4	0.4	-1.5	1.7	-0.1	-1.1	-0.3
Commuting to job workplace: Public transport	0.7	0.9	7.6	-0.5	1.1	1.3	-0.7	0.7	0.2	-0.1	-0.0	-0.0	-0.7	-1.0	0.2	2.7	-0.9	0.3	-0.3	-0.6
Pain type(s) experienced in last month: Hip pain	0.7	0.9	10.3	-0.5	0.3	-1.0	0.1	-0.1	3.2	1.0	0.6	-0.2	-0.1	-0.5	-0.7	-0.4	0.6	0.4	-0.7	-0.6
Medication: Bendroflumethiazide	0.7	1.0	8.6	-0.7	-1.0	0.9	1.2	-0.8	1.3	-1.0	-0.2	-0.7	0.3	-0.2	-0.5	-2.9	0.7	0.4	-0.3	-0.6
Medication: Paracetamol	0.7	1.1	5.0	1.6	-0.4	0.1	-0.0	0.6	-0.1	1.0	0.5	-0.7	0.4	1.5	-2.2	-1.4	0.7	-0.9	1.1	1.3
Risk taking	0.7	1.0	3.7	-0.4	1.3	1.7	0.0	0.1	-0.1	0.3	0.2	0.4	-0.7	-1.9	0.3	-0.4	0.0	1.5	-1.5	-1.7
Verbal and Numeric Reasoning (VNR)	0.6	1.5	6.1	-2.5	1.7	1.8	-0.6	0.3	0.2	-0.6	-0.2	0.3	-1.2	-1.9	0.7	0.6	-0.1	1.8	-0.2	-1.5
Fasting Glucose	0.6	0.7	3.6	-0.7	1.4	-0.1	-0.8	0.4	0.4	0.0	0.5	0.6	-0.9	-0.3	1.9	1.1	0.3	0.6	-0.9	-0.5
Smoking Status	0.6	1.4	8.9	0.1	-1.4	0.2	3.0	1.1	-0.3	1.0	-1.9	-1.1	0.3	0.5	-1.1	-1.2	0.1	-0.0	1.6	1.1
Leg fat-free mass (left)	0.6	3.0	6.8	-2.1	1.1	2.3	-1.5	0.8	-0.0	2.6	2.5	0.6	-1.8	-0.7	1.8	1.3	2.4	2.4	-1.4	-1.2
Townsend deprivation index at recruitment	0.6	0.8	3.3	0.2	0.7	0.1	1.4	1.8	0.4	1.1	-0.2	1.2	-0.2	-0.1	0.7	1.7	-1.0	-0.3	0.6	0.1
Sitting height	0.6	4.3	10.4	-2.7	0.6	2.7	-1.7	0.7	0.5	3.2	2.9	0.9	-2.0	-0.5	3.2	1.1	2.5	2.5	-2.1	-1.4
Leg predicted mass (left)	0.6	3.1	6.9	-2.3	1.2	2.2	-1.6	0.8	0.0	2.6	2.6	0.7	-1.8	-0.8	1.8	1.3	2.3	2.5	-1.5	-1.3
Hearing difficulty/problems with background noise	0.6	1.0	4.5	0.4	0.9	-0.5	-0.5	-2.1	1.6	-1.4	-0.5	-0.3	0.9	-1.2	-0.4	0.4	-1.2	-0.2	-1.1	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	8.7	3.0	-0.7	-0.8	1.2	0.9	0.0	0.8	-1.4	-0.8	0.4	1.0	-1.5	-1.5	0.1	-1.3	0.2	1.2
Neuroticism score	0.6	1.2	5.2	-1.1	0.8	0.6	-1.0	-1.9	0.3	-0.5	0.5	-0.3	-0.2	-1.6	0.6	0.1	0.9	1.3	-2.3	-1.5
Number of live births	0.6	0.9	2.9	0.6	-0.9	-0.9	0.5	-1.3	-0.2	0.4	-0.6	-1.7	0.6	0.8	-1.6	-0.9	1.5	-0.2	-0.3	0.4
Loud music exposure frequency	0.6	0.7	6.3	0.1	-0.0	-0.6	-0.6	0.0	-0.2	0.3	-0.8	1.0	0.3	0.0	-0.7	1.1	-2.5	-0.7	0.3	0.1
Birth weight	0.6	1.4	8.5	-2.9	0.1	1.4	-1.0	0.2	0.5	0.6	1.4	0.6	-0.8	-0.6	0.7	1.8	-0.2	1.5	0.7	-1.1
Age at first live birth	0.6	1.1	2.9	-1.6	0.9	1.4	-0.6	1.7	-0.9	-1.1	0.4	1.0	-1.0	-0.5	1.2	1.3	-0.6	0.9	1.1	-0.4
Supplements: Vitamin C	0.6	0.7	2.7	-0.8	-0.0	0.1	-0.9	0.2	1.6	1.5	-0.1	0.5	-1.1	-1.0	0.4	0.9	-0.3	1.2	-0.4	-1.0
Illnesses of siblings: Diabetes	0.6	0.8	2.5	1.1	-0.4	-1.2	0.0	-0.5	-0.6	-0.4	-0.5	-0.5	1.2	1.2	-1.6	0.6	-0.6	-1.6	0.2	1.0
Leg fat-free mass (right)	0.6	3.2	7.6	-2.2	1.3	2.3	-1.4	0.9	0.1	2.8	2.5	0.7	-1.8	-0.8	2.0	1.4	2.3	2.5	-1.6	-1.3
Medication: Gliclazide	0.6	0.7	2.8	0.7	-1.0	-0.3	1.7	0.6	1.0	0.6	0.5	-0.8	0.7	1.2	-0.4	-0.7	0.7	-0.6	0.7	1.0
Leg predicted mass (right)	0.6	3.2	7.4	-2.2	1.2	2.3	-1.5	0.8	0.1	2.7	2.5	0.7	-1.8	-0.8	2.0	1.3	2.3	2.5	-1.6	-1.3
Financial situation satisfaction	0.6	0.7	2.1	-1.5	-0.0	1.0	-1.1	-0.8	-1.2	-0.5	-0.5	0.7	-0.5	-1.2	0.0	-0.6	0.1	1.3	0.0	-0.7
Irritability	0.6	1.1	3.9	-2.0	-0.3	0.8	0.1	-1.1	-0.9	-0.8	-0.8	-0.6	-0.0	-1.8	-0.0	-0.1	-1.0	1.8	-0.8	-1.4
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.6	-1.6	0.3	-0.6	-0.5	-0.8	-1.1	-1.4	0.4	0.6	-0.1	-1.4	0.5	0.6	-0.4	0.6	-0.5	-1.1
Major Depression (MDD)	0.5	0.6	6.5	0.0	0.0	0.0	0.8	0.0	0.0	-0.1	-0.9	0.0	0.0	2.5	-1.4	0.6	0.0	0.0	0.0	0.0
Blood Platelet Count	0.5	5.5	25.3	-4.1	1.9	1.0	-4.3	-1.4	-1.8	-3.2	2.5	1.1	-0.6	-1.1	1.4	5.0	-0.1	0.6	0.8	-1.1
Allergy or Eczema	0.5	1.3	7.9	-0.7	1.2	1.7	-2.8	-0.8	0.4	-0.2	1.0	-0.8	-1.0	-0.6	0.9	1.2	1.2	0.4	-1.2	-1.0
Respiratory disease	0.5	1.1	3.4	1.1	-0.3	-0.7	1.3	0.9	-0.8	1.1	-0.5	-1.8	0.1	1.5	-0.5	1.0	0.8	-1.1	1.4	1.2
Current tobacco smoking	0.5	0.8	2.5	-0.7	-1.6	0.9	1.2	-0.4	0.7	0.3	-1.3	-1.3	0.6	0.2	-0.4	-1.4	-0.3	0.4	1.0	0.2
Taking other prescription medications	0.5	0.8	2.8	1.0	-1.2	-0.9	1.4	0.2	0.4	1.0	-1.0	-1.3	0.4	0.7	-0.1	-1.7	0.5	-0.7	0.5	0.6
High blood pressure (mother)	0.5	0.7	7.0	0.9	0.4	-0.1	0.7	-0.3	-0.3	-0.6	-0.2	0.9	0.2	-0.3	-0.1	-2.6	0.9	0.1	-1.1	-0.2
Worrier / anxious feelings	0.5	1.0	5.4	-1.3	0.3	0.7	-0.8	-2.3	0.3	-1.6	0.5	-0.9	0.4	-0.7	0.2	0.7	0.6	0.6	-1.3	-0.9
Prospective memory result	0.5	0.6	2.2	-0.3	-0.3	0.9	1.2	0.2	-1.5	-0.4	-0.6	-1.2	-0.0	-0.5	0.6	-1.5	0.8	0.5	0.1	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	7.8	-1.1	0.7	1.1	-0.8	0.9	0.5	2.8	1.2	0.8	-1.2	0.2	2.4	0.8	0.9	1.2	-0.5	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	5.7	2.4	0.4	-0.7	-0.4	-0.3	0.3	1.2	-0.7	-0.3	-0.5	-0.8	-0.2	0.5	0.0	0.0	-1.5	-0.9
Peak expiratory flow (PEF)	0.5	1.1	3.7	0.2	0.6	-0.1	0.8	1.5	0.3	1.9	1.7	-0.3	-0.7	0.6	1.4	1.8	1.6	0.1	-0.3	0.1
Forced vital capacity (FVC), Best measure	0.5	1.7	7.0	-2.0	0.1	1.7	-0.9	0.3	1.1	2.4	1.5	0.3	-1.0	0.1	2.6	1.0	0.9	1.5	-0.5	-0.6
Arm fat-free mass (right)	0.5	2.8	8.0	-2.7	0.5	2.7	-0.3	0.5	-0.7	2.1	2.2	0.2	-1.3	-0.9	1.5	-0.1	2.4	2.8	-1.5	-1.2
Qualifications: College or University degree	0.5	1.6	5.8	-2.3	1.1	0.8	-1.1	0.6	-0.2	0.2	-0.0	1.2	-1.1	-1.7	0.9	2.4	-1.6	1.4	0.2	-1.3
Eye problems/disorders: None of the above	0.5	0.6	2.6	-0.6	-0.1	1.3	-0.9	-1.1	-1.0	-1.6	-0.1	0.1	0.2	-0.8	0.1	0.3	-0.9	0.2	-0.6	-0.7
Medication: Ibuprofen	0.5	0.6	2.9	0.7	-1.4	-0.3	0.5	-0.4	-0.7	-0.3	-0.4	-0.9	0.8	1.1	-0.4	-1.7	0.4	-0.8	-0.1	0.5
Arm predicted mass (right)	0.5	2.6	7.5	-2.7	0.5	2.6	-0.5	0.3	-0.5	2.0	2.1	0.2	-1.3	-0.8	1.6	-0.1	2.1	2.7	-1.5	-1.3
Illnesses of father: Heart disease	0.5	0.7	4.9	-0.3	-0.8	-0.7	-1.0	-0.8	-0.1	-1.2	0.1	0.2	0.3	0.4	-2.2	-1.6	0.2	-0.1	-0.2	-0.3
Whole body fat-free mass	0.5	2.7	7.6	-2.8	0.8	2.6	-0.7	0.5	-0.7	2.2	2.2	0.3	-1.3	-0.8	1.7	0.7	2.2	2.6	-1.4	-1.1
Ever had bowel cancer screening	0.5	0.6	3.6	-0.6	-1.2	0.0	-0.3	-1.0	-0.4	-0.8	-0.3	-0.0	0.8	-0.0	-0.6	0.9	-1.9	-0.5	0.4	-0.0
Friendships satisfaction	0.5	0.7	2.7	0.9	-0.4	0.3	0.9	0.0	-1.4	-0.4	-1.6	-1.1	0.5	0.1	-1.4	-0.3	0.2	-0.4	0.7	0.8
Whole body water mass	0.5	2.7	7.2	-2.7	0.8	2.6	-0.7	0.5	-0.6	2.2	2.2	0.2	-1.4	-0.8	1.6	0.7	2.2	2.6	-1.4	-1.1
Eye problems/disorders: Glaucoma	0.5	0.6	1.4	-0.4	1.2	0.9	-0.4	1.0	0.0	0.7	1.2	0.4	-1.1	-0.4	0.6	1.1	0.9	0.5	-0.2	-0.3
Unable to work because of sickness or disability	0.5	0.6	3.4	0.5	-0.2	0.2	1.1	0.2	-0.7	1.3	-0.6	-1.0	-0.5	0.1	0.8	-0.9	1.9	0.3	-0.1	0.1
Bipolar Disorder (2018)	0.4	0.6	2.6	0.5	-0.6	-0.2	0.0	0.5	-1.4	-0.2	1.6	0.5	0.1	0.7	-1.2	-0.9	1.2	-0.1	0.4	0.7
Depression (Nagel 2018)	0.4	0.6	2.4	0.0	-1.1	-0.3	-0.2	-1.3	-0.8	-0.8	-0.1	-0.9	0.9	0.3	-1.5	-1.2	-0.4	-0.3	-0.1	0.3
Neuroticism (Nagel 2018)	0.4	1.0	4.3	-1.4	0.1	0.8	-1.2	-2.1	-0.6	-1.0	-0.1	-0.5	-0.3	-1.6	0.1	0.4	0.5	1.1	-1.4	-1.2
Ovarian Cancer	0.4	0.6	1.6	1.3	-0.4	-0.8	-0.3	-0.8	-0.3	-0.6	-1.1	-0.8	0.8	0.5	-0.9	-0.6	-1.0	-1.0	-0.0	0.6
Neuroticism (2016)	0.4	0.5	1.9	-0.6	0.1	0.8	-0.9	-1.2	0.3	-0.8	0.5	-0.5	0.0	-0.9	0.1	-0.2	0.5	0.6	-1.4	-0.8
Heel T-Score	0.4	3.0	12.5	3.1	-1.6	-0.6	3.5	0.6	1.6	1.3	-2.2	-2.3	0.7	1.5	-0.2	-1.1	0.4	-1.8	0.9	1.7
Height	0.4	7.1	22.8	-3.9	0.9	2.9	-2.8	-0.3	0.4	4.8	3.6	0.1	-1.6	0.0	2.9	4.7	3.4	2.5	-1.5	-0.7
Neuroticism	0.4	1.1	4.6	-2.1	0.1	0.4	-1.0	-2.1	-0.5	-1.0	-0.7	-0.4	0.2	-1.5	0.4	0.5	-0.5	1.1	-0.8	-1.1
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.4	0.4	-0.4	0.2	0.1	-1.4	1.0	-0.7	0.1	-0.8	0.6	-0.2	-0.5	-1.5	0.7	-0.2	-1.5	-0.5
Pack years adult smoking proportion	0.4	0.5	2.8	-0.9	-0.5	1.7	0.3	-0.1	-1.2	0.4	-0.4	0.0	-0.2	-0.7	-0.7	-1.1	-0.1	1.1	0.3	-0.2
Impedance of leg (right)	0.4	1.9	5.7	1.3	-1.7	-1.6	-0.5	-1.9	-0.3	-2.4	-1.0	-1.2	1.5	1.1	-1.4	-0.2	-1.0	-2.0	0.9	1.0
Impedance of leg (left)	0.4	2.1	5.5	1.4	-1.8	-1.7	-0.5	-2.0	-0.0	-2.3	-1.3	-1.1	1.8	1.3	-1.2	0.2	-1.3	-2.1	0.9	1.0
Nervous feelings	0.4	0.8	3.7	-0.1	0.0	-0.3	-0.5	-1.9	0.8	-1.2	-0.3	-1.3	0.4	-0.1	-0.3	-0.4	1.4	-0.2	-1.6	-0.3
Impedance of arm (right)	0.4	2.1	7.9	1.7	-0.4	-2.0	-2.5	-1.2	1.2	-0.9	-0.2	-0.2	0.7	1.3	-0.2	2.8	-1.0	-2.3	0.7	0.8
Trunk fat-free mass	0.4	2.4	7.8	-2.8	0.5	2.7	0.0	0.3	-1.3	1.9	1.9	-0.0	-0.9	-0.8	1.4	0.2	2.1	2.5	-1.3	-1.0
Alcohol intake versus 10 years previously	0.4	0.7	3.6	-1.9	-0.2	0.3	1.4	0.2	-0.9	-0.9	0.8	0.1	0.3	-0.2	-0.1	0.9	0.1	0.1	1.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.0	-1.4	0.3	0.5	-0.6	0.0	0.1	0.6	0.4	0.6	-0.8	-1.0	1.1	-0.5	1.1	1.3	-0.7	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.8	0.6	-1.1	-1.2	0.4	-1.0	-0.5	-0.6	-0.8	-0.4	0.8	0.2	0.3	-1.3	-0.0	-0.4	-0.2	0.0
Trunk predicted mass	0.4	2.5	8.0	-2.8	0.6	2.6	-0.0	0.2	-1.2	1.8	2.0	-0.0	-1.0	-0.8	1.5	0.2	2.1	2.6	-1.5	-1.1
Pulse wave reflection index	0.4	0.5	2.2	-0.9	-0.1	0.7	-0.5	-0.7	1.5	-0.2	-0.6	-0.6	-0.6	-1.0	0.6	0.1	-0.1	0.5	-0.4	-1.2
Gout (self-reported)	0.4	0.5	1.8	1.0	-1.0	0.4	0.6	0.2	0.3	0.0	-0.3	-0.2	0.5	0.7	-1.3	-1.3	-0.8	-0.7	0.5	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.8	-1.0	-0.6	-0.5	0.9	1.0	0.2	0.6	-1.2	-1.3	-0.1	0.3	0.3	1.1	-0.1	-0.1	1.1	0.3
Number of children fathered	0.4	0.5	1.9	1.2	0.9	-1.0	-0.4	-0.4	-0.2	-0.1	-0.1	0.2	0.4	0.7	0.1	1.3	-0.2	-1.4	0.3	0.4
Heart disease (mother)	0.4	0.5	1.7	-1.1	1.1	0.7	-0.6	0.0	-0.1	0.1	0.3	1.3	-0.1	-1.2	0.8	0.1	-0.4	1.0	-0.4	-0.7
Comparative height size at age 10	0.4	2.1	5.9	-0.7	-1.8	-0.2	0.3	-1.3	-0.1	2.3	-0.4	-2.4	1.5	2.3	-0.9	2.4	-0.5	-0.5	1.2	1.7
Suffer from ‘nerves’	0.4	0.7	3.5	-0.6	-0.3	-1.0	-1.0	-1.9	0.8	-0.3	0.1	-0.9	0.4	-0.1	1.0	1.5	0.8	0.1	-0.8	-0.3
Knee pain experienced in last month	0.4	0.6	2.8	0.7	-0.3	-0.6	1.4	0.3	-0.2	0.5	-0.8	-1.2	0.7	0.4	-1.7	-0.1	-0.3	-0.6	0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	3.3	-1.0	0.3	0.2	-1.0	-1.1	-0.1	1.2	0.6	0.1	0.1	-0.5	1.7	1.3	-0.2	1.0	-1.8	-1.0
Average weekly red wine intake	0.4	0.6	2.1	-0.9	-0.1	0.3	-1.3	-0.6	1.4	-0.8	0.5	0.8	-0.4	-0.6	1.1	-0.1	-0.4	0.3	-0.7	-0.7
Handedness (chirality/laterality): Left-handed	0.4	0.5	3.1	-0.7	-0.3	0.6	0.1	-0.6	-1.1	-1.8	0.1	0.0	0.6	-0.1	0.9	0.8	-0.7	-0.5	0.3	-0.2
Mood swings	0.4	0.8	3.1	0.4	-0.3	1.0	-1.2	-1.7	-0.9	-0.8	0.3	-0.5	0.2	-1.0	0.1	-0.5	0.2	0.2	-1.8	-0.9
Commuting to job workplace: Walk	0.4	0.4	1.5	-0.7	0.8	0.5	-0.1	-0.5	0.0	-1.2	0.2	0.1	-0.1	-1.2	0.3	-0.1	-0.1	0.5	-0.9	-0.9
Smoking status: Current	0.4	0.7	2.0	-0.8	-1.4	1.1	1.2	-0.2	0.7	0.4	-1.2	-1.1	0.3	0.0	0.0	-1.3	-0.1	0.6	1.0	0.0
Miserableness	0.4	0.6	1.8	-0.7	0.7	0.8	-0.2	-0.6	-0.9	0.1	0.3	0.2	-0.7	-1.0	0.7	-0.2	1.2	1.1	-1.3	-0.9
Hearing aid user	0.4	0.5	3.5	1.1	-0.2	-0.5	1.1	0.9	0.5	0.2	-0.5	-0.0	-0.1	0.3	-0.8	-1.9	0.1	-0.3	0.3	0.2
Mother’s age at death	0.4	0.5	2.5	-0.2	-0.0	-0.4	-0.4	-1.0	-1.6	-0.9	0.3	-0.0	0.9	0.6	-0.2	1.3	-0.5	-0.6	0.6	0.9
Basal metabolic rate	0.4	2.4	5.5	-2.4	0.6	2.2	-1.0	0.4	-0.7	2.2	2.2	0.2	-1.3	-0.5	1.5	1.1	2.1	2.3	-1.2	-0.9
Number of operations (self-reported)	0.4	0.6	2.0	-0.5	-0.2	-0.6	-0.3	-1.4	-0.9	-1.2	0.2	-0.2	1.2	-0.3	-1.3	-0.4	-1.0	0.1	0.3	-0.2
Average weekly beer plus cider intake	0.4	0.6	2.2	1.5	-0.1	-0.5	1.1	0.8	-0.7	-0.8	-0.3	-0.6	0.4	0.8	-0.4	0.2	0.3	-1.3	0.6	1.1
Ever depressed for a whole week	0.4	0.4	2.2	1.5	-1.1	0.3	0.8	0.4	0.4	0.2	-0.9	-0.1	0.1	0.5	0.1	-0.2	-0.8	-0.9	0.7	0.5
Reaction Time	0.3	0.5	2.0	0.3	1.2	0.2	0.3	1.0	-0.2	-0.1	0.6	0.9	0.2	1.0	0.0	0.5	0.2	-0.8	1.1	1.4
Body Mass Index (BMI) (2010)	0.3	0.4	1.7	-0.6	-0.0	0.7	1.0	1.3	0.9	0.1	0.6	0.6	-0.4	-0.2	-0.0	0.9	-0.1	0.1	0.5	-0.0
Mean Putamen Volume	0.3	0.3	0.9	0.7	0.8	-0.9	-0.2	-0.1	0.2	-0.4	0.4	-0.8	-0.0	0.3	-0.0	0.6	1.0	-0.7	-0.4	0.4
HDL Cholesterol	0.3	0.5	1.5	-1.0	-0.2	0.3	-0.8	-1.0	1.0	-1.2	0.2	-0.3	-0.0	-0.6	0.2	-1.2	0.7	0.5	-0.1	-0.5
Lupus	0.3	0.5	2.7	-0.0	-0.7	-0.1	0.7	0.7	-0.2	1.6	-1.7	-0.0	-0.3	0.1	0.6	-0.0	-0.8	-0.1	0.9	0.4
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.5	0.4	-1.0	-0.6	1.3	1.0	0.7	1.6	-0.5	-0.5	0.0	1.0	-0.6	-0.1	0.1	-0.2	0.9	0.9
Hair Pigment	0.3	7.4	30.1	4.1	-0.6	-1.8	5.5	3.5	-0.6	0.3	-2.6	-0.8	1.6	2.5	-2.5	-1.3	-0.2	-3.1	3.2	4.2
Hand grip strength (left)	0.3	0.9	1.9	0.7	-0.9	-0.3	1.0	-0.1	-0.8	0.6	-1.3	-1.3	0.9	1.3	-1.3	-0.9	-0.2	-0.9	0.9	1.4
Trunk fat percentage	0.3	1.1	6.6	0.9	-0.4	-0.8	-2.6	-0.1	-0.2	0.9	1.3	-0.0	-0.5	1.1	0.1	2.3	0.6	-0.6	0.2	0.4
Maternal smoking around birth	0.3	0.4	1.0	0.5	-0.8	-0.0	0.9	-0.6	0.8	1.0	-0.8	-0.5	0.8	0.7	-0.3	0.2	-1.0	-0.6	0.4	0.2
Fed-up feelings	0.3	0.6	2.4	0.0	-0.0	0.4	-0.5	-1.2	0.3	0.2	0.4	-0.9	-0.3	-0.7	0.6	-0.7	1.6	0.8	-1.4	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	3.3	1.8	-0.2	-0.7	0.4	1.3	0.9	0.8	-1.3	0.3	-0.4	0.2	-0.5	-0.4	-0.6	-0.8	0.4	0.5
Supplements: Glucosamine	0.3	0.4	1.8	0.1	0.4	0.6	1.1	1.2	-0.7	0.4	-0.1	0.9	-0.2	0.1	-0.2	-1.4	-0.6	0.3	0.3	0.2
Waist circumference	0.3	1.0	3.2	1.1	-1.0	-0.5	0.1	-0.3	-1.6	0.9	0.0	-1.2	0.8	1.8	-1.2	0.5	0.8	-0.9	0.8	1.5
Had menopause	0.3	0.4	1.7	-0.5	-0.3	0.1	0.1	-1.1	-0.6	-1.3	1.3	-0.5	0.6	-0.2	0.0	-0.1	0.7	-0.3	-0.6	-0.3
Had other major operations	0.3	0.3	2.8	-0.4	-0.0	-0.2	-0.8	-0.9	-0.7	-1.7	0.4	-0.1	0.6	0.1	-0.0	0.1	-0.2	-0.5	-0.1	-0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.2	-0.1	0.5	0.8	-0.5	0.2	-0.2	0.1	-0.3	0.8	-0.6	-0.8	1.1	-0.5	0.1	0.5	-0.5	-0.7
Allergy	0.3	0.7	3.2	-0.3	-1.0	-0.8	0.9	-0.1	0.9	-0.5	-0.5	1.4	0.7	-0.2	-0.5	-1.0	-1.8	-0.0	0.9	0.2
Weight	0.3	1.3	4.2	-1.1	0.1	0.9	-1.6	0.1	-1.0	1.9	2.1	-0.1	-0.8	0.3	0.8	1.6	1.6	1.2	-0.6	-0.2
Impedance of arm (left)	0.3	1.6	8.1	1.4	0.3	-1.5	-2.8	-0.5	1.7	-0.3	0.5	0.3	-0.3	0.8	0.7	2.8	-0.4	-1.5	0.2	0.2
Standing height	0.3	3.4	10.8	-3.3	0.3	2.5	-2.1	-0.7	-0.2	2.3	2.4	-0.1	-0.9	-0.3	2.3	2.5	2.0	2.2	-1.4	-1.0
Birth weight of first child	0.3	0.5	1.6	-1.3	0.9	0.1	-0.2	0.8	0.3	0.2	1.1	0.4	-0.6	-0.4	0.6	0.9	0.8	0.8	-0.2	-0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.3	1.5	0.2	0.4	0.2	-0.3	-0.2	0.2	-0.5	-0.3	0.4	-0.4	-1.1	0.6	-0.6	-0.6	-0.8	0.0
Pulse wave peak to peak time	0.3	0.3	1.8	0.6	0.6	-0.3	-1.3	-0.6	-0.4	-0.2	0.8	-0.1	0.1	0.2	-0.4	0.6	0.6	-0.4	-0.7	0.3
Medication: Allopurinol	0.3	0.4	3.1	0.8	-0.4	1.1	0.2	0.2	-0.3	0.6	0.6	0.1	-0.0	0.0	-0.7	-1.8	0.6	0.0	-0.3	-0.1
Medication: Omeprazole	0.3	0.4	1.9	0.7	-0.1	-0.6	0.6	0.3	1.4	0.8	0.2	0.0	-0.1	0.6	0.2	0.3	1.3	-0.5	-0.1	0.3
Medication: Seretide 50 evohaler	0.3	0.4	1.5	-1.2	-0.3	0.1	-0.2	0.1	1.0	1.2	-0.2	-0.9	-0.6	-0.4	-0.1	0.4	-0.2	0.6	0.3	-0.4
Leg pain on walking	0.3	0.4	1.6	0.9	0.0	0.9	0.3	0.6	1.1	1.3	0.1	-0.3	-0.4	-0.1	-0.6	-0.7	0.0	0.4	0.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.0	0.3	0.2	-0.1	-0.3	-1.0	0.5	-0.7	0.9	0.5	0.6	0.5	1.0	0.2	0.2	-0.6	-0.6	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.8	0.2	-0.8	-0.4	0.0	-0.5	-1.0	0.6	-1.1	-1.4	0.4	0.4	-0.7	1.1	-0.6	-0.7	0.3	0.4
Arm fat-free mass (left)	0.3	1.7	5.3	-2.3	0.1	2.0	-0.3	0.4	-0.8	2.1	1.7	-0.1	-0.9	-0.2	1.0	0.4	1.9	2.1	-0.9	-0.7
Fractured/broken bones in last 5 years	0.3	0.4	1.7	-1.3	-0.4	0.1	-0.6	-1.1	-0.0	0.6	0.5	0.4	0.0	-0.5	0.5	-0.6	0.2	0.9	-0.9	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.1	0.8	-0.6	-1.0	0.4	-0.4	0.7	-0.0	-0.0	-0.4	0.5	0.6	-0.4	-0.6	0.8	-0.8	-0.2	0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.3	0.6	-0.2	0.5	0.7	-0.5	-0.2	0.1	-0.4	0.0	1.1	0.7	-0.5	-0.0	-1.0	-1.1	0.7	0.7
Pack years of smoking	0.3	0.4	2.1	-0.9	-0.4	1.5	0.5	0.1	-1.0	0.2	-0.6	0.1	-0.1	-0.4	-0.6	-0.6	-0.1	0.6	0.8	0.2
Impedance of whole body	0.3	1.6	4.2	1.6	-0.8	-1.7	-2.1	-1.2	1.2	-1.2	-0.4	-0.5	0.6	1.3	-0.2	1.9	-0.9	-2.0	0.7	0.7
Arm predicted mass (left)	0.3	1.5	4.8	-2.2	0.1	2.1	-0.4	0.0	-0.9	1.8	1.6	-0.3	-0.7	-0.3	0.9	0.5	1.9	2.0	-1.0	-0.7
Depressed Affect (Nagel 2018)	0.2	0.5	3.2	-0.5	-0.9	0.1	-0.7	-1.8	-0.7	-0.3	-0.6	-0.7	0.4	-0.6	-0.9	-0.3	-0.2	0.3	-0.3	-0.4
Worry (Nagel 2018)	0.2	0.5	2.0	-0.6	0.5	0.1	-0.7	-1.4	0.6	-0.0	-0.2	-0.4	-0.2	-0.8	0.2	0.9	0.7	0.7	-1.3	-0.8
Rheumatoid Arthritis	0.2	0.3	0.9	0.6	0.6	0.2	0.2	0.9	0.5	0.0	0.7	0.3	-0.6	0.0	0.0	0.8	0.8	-0.2	-0.4	-0.2
BMI	0.2	1.4	4.3	-0.7	0.6	0.9	-1.3	0.1	0.1	0.9	1.6	0.7	-1.6	-1.7	0.6	-0.4	1.1	2.1	-1.5	-1.7
Lung FVC	0.2	1.0	3.6	-1.7	-0.9	0.8	0.3	0.7	0.9	0.3	-0.3	-0.5	-0.1	0.4	1.9	1.9	-1.1	-0.2	1.2	0.0
Medication for hormone replacement therapy	0.2	0.2	0.9	0.9	0.1	0.3	-0.4	0.3	-0.8	0.1	1.0	0.1	-0.5	-0.1	0.0	-0.2	0.8	0.2	-0.1	-0.1
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	-0.2	-0.1	0.4	0.4	-0.5	-0.3	-0.1	0.8	-0.2	-0.0	-0.8	0.5	-0.1	0.7	0.4	-0.8	-0.6
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.0	0.3	-0.3	-0.1	0.2	-0.6	-0.7	-0.5	0.3	-0.1	0.7	-0.0	-1.0	0.6	-0.3	-0.5	-0.6	0.2
Trunk fat mass	0.2	0.9	4.8	0.1	-0.4	0.0	-2.2	-0.1	-0.5	1.4	1.7	-0.1	-0.6	0.8	0.4	2.0	1.0	0.2	-0.1	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	2.1	-0.4	0.1	0.3	-0.3	-0.6	1.4	-0.5	-0.3	-1.0	0.2	-0.6	0.1	0.1	0.0	0.1	-0.6	-0.5
Heart attack	0.2	0.3	1.1	0.4	-0.3	0.4	0.7	-0.5	-0.0	0.2	-0.3	0.0	1.1	0.7	-0.3	-0.1	-0.7	-1.0	0.5	0.6
Arm fat percentage (right)	0.2	0.9	2.8	1.4	-0.6	-1.4	-1.6	-0.3	-0.5	0.3	0.7	-0.6	0.2	1.2	-0.5	1.7	0.1	-1.1	0.4	0.8
Hip circumference	0.2	0.7	5.7	0.2	-0.1	-0.6	-1.5	0.2	-0.4	1.8	0.6	0.1	-0.3	0.5	-0.1	2.4	0.0	-0.0	-0.0	0.4
Time employed in main current job	0.2	0.3	0.7	0.7	-0.8	-0.1	0.4	-0.1	0.6	-0.0	-0.8	-0.8	0.2	-0.0	0.1	0.8	-0.8	-0.3	0.0	-0.1
Father’s age at death	0.2	0.3	1.0	-0.6	0.4	0.9	-0.0	-0.2	0.2	-1.0	0.4	0.4	-0.1	-1.0	0.7	0.8	-0.2	0.4	-0.3	-0.8
Pulse wave Arterial Stiffness index	0.2	0.3	1.8	-0.5	-0.6	0.3	1.3	0.5	0.5	0.5	-0.6	0.1	-0.1	-0.1	0.5	-0.5	-0.4	0.4	0.5	-0.2
Arm fat mass (right)	0.2	0.7	2.5	0.3	-0.3	-0.4	-1.6	-0.1	-0.9	1.2	1.4	-0.4	-0.3	0.8	-0.0	1.5	1.1	0.0	-0.1	0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.4	-0.2	1.2	1.1	0.0	0.5	-0.5	0.0	-0.3	0.4	-0.5	-0.4	0.5	0.9	0.3	0.3	0.3	0.0
Body fat percentage	0.2	0.8	4.4	0.9	-0.6	-1.0	-2.1	-0.3	-0.5	0.4	1.1	-0.2	-0.2	1.0	-0.2	1.6	0.3	-0.7	0.3	0.5
Leg fat percentage (right)	0.2	0.7	1.6	1.0	-1.2	-1.1	-0.7	-0.1	-1.1	-0.2	0.2	-0.5	0.4	1.3	-1.0	0.5	-0.2	-1.1	1.2	1.1
Comparative body size at age 10	0.2	0.4	1.3	0.7	-0.4	-0.3	-0.9	-0.4	0.9	1.1	0.3	-0.4	0.3	1.1	-0.9	-0.1	0.1	-0.5	0.8	0.8
Whole body fat mass	0.2	0.7	3.7	-0.0	-0.4	-0.1	-1.9	-0.3	-0.9	0.8	1.6	-0.4	-0.3	0.7	0.1	1.6	0.9	0.1	-0.1	0.1
Arm fat percentage (left)	0.2	0.7	3.0	1.2	-0.1	-1.0	-1.7	0.1	-0.2	0.7	1.2	-0.1	-0.4	0.8	0.1	1.5	0.7	-0.5	0.0	0.3
Mineral and other dietary supplements	0.2	0.3	0.7	-0.0	0.6	0.6	-0.6	-0.2	-0.0	0.4	0.3	0.6	-0.3	-0.6	0.7	0.1	0.5	0.5	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	1.2	-0.5	-0.5	-0.8	0.0	0.8	0.6	1.1	0.1	0.4	-0.1	0.6	0.7	0.6	-0.5	-0.0	0.8	0.3
Arm fat mass (left)	0.2	0.7	3.3	0.0	-0.1	-0.3	-1.8	-0.3	-0.6	0.9	1.7	-0.3	-0.5	0.6	0.2	1.7	1.1	0.2	-0.3	-0.0
Wears glasses or contact lenses	0.2	0.2	1.6	-0.4	0.4	-0.3	0.1	0.7	0.1	0.5	-0.6	0.2	-0.2	-0.2	1.3	0.5	-0.2	-0.2	0.6	0.3
Leg fat percentage (left)	0.2	0.7	1.8	1.0	-1.2	-1.1	-0.6	-0.1	-0.9	-0.0	0.1	-0.4	0.5	1.4	-0.9	0.7	-0.3	-1.1	1.2	1.0
Alcohol drinker status: Previous	0.2	0.3	1.1	-0.4	0.4	-0.2	0.3	0.9	0.0	0.8	0.2	0.2	-0.2	0.3	1.0	0.5	0.9	-0.0	0.4	0.3
Lung FEV1/FVC ratio	0.1	0.6	3.0	0.5	0.1	-1.4	1.7	0.7	-0.8	-0.0	-0.6	-0.1	0.5	0.9	-0.5	-0.3	0.1	-0.5	1.1	0.9
Tanning	0.1	0.7	5.1	0.3	0.1	0.4	-0.7	-1.2	-2.3	-1.2	-0.7	-0.7	0.1	-0.7	-0.1	-0.1	-0.0	-0.1	-1.1	-0.7
Hand grip strength (right)	0.1	0.3	1.6	-0.3	0.0	0.6	0.3	0.6	-0.1	1.3	0.2	-0.0	-0.1	0.4	-0.5	-1.2	0.5	0.4	-0.2	0.4
Body mass index (BMI)	0.1	0.3	1.2	0.5	-0.1	-0.3	-0.6	0.5	-1.0	1.1	1.0	-0.1	-0.4	0.5	-0.3	0.5	0.8	0.2	0.1	0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	0.4	0.4	-0.9	0.6	0.6	-0.8	0.1	0.5	0.2	0.3	-0.3	-0.2	0.5	0.1	-0.4	-0.2	0.2
Depression (self-reported)	0.1	0.2	0.8	0.5	-0.4	-0.3	-0.6	-0.6	-0.5	0.2	0.0	-0.0	0.3	-0.3	-0.2	0.2	-0.9	-0.1	0.3	-0.1
Wheeze or whistling in the chest in last year	0.1	0.3	0.9	0.0	-0.0	0.4	0.9	0.8	-0.4	1.0	-0.5	-0.3	-0.4	-0.0	0.2	-0.2	0.9	0.4	0.2	-0.1
Health satisfaction	0.1	0.2	1.2	-0.4	-0.7	-0.0	-0.2	0.0	-0.0	-0.0	-0.1	-0.0	-0.1	-0.4	-0.2	-1.1	0.4	0.7	-0.0	-0.2
Leg fat mass (right)	0.1	0.4	1.8	0.1	-0.6	-0.1	-1.3	-0.2	-0.9	0.6	1.0	-0.3	-0.1	0.7	-0.3	0.7	0.7	0.1	0.2	0.3
Leg fat mass (left)	0.1	0.4	1.4	0.1	-0.8	-0.3	-1.2	-0.3	-1.0	0.6	0.8	-0.4	0.0	0.8	-0.4	0.8	0.4	-0.1	0.3	0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

RASA3

Models

Trait associations