[Hub]/) : Traits : Blood Eosinophil Count :

chr17:73,059,836-75,194,387

Best TWAS P=1.93e-11 · Best GWAS P=3.47e-12 conditioned to 0.0349

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RHBDF2 0.21 0.17 lasso 4 0.16 8.0e-13 5.2 5.2 2.5e-07 -0.01 0.97 0.03 TRUE
2 GTEx Adipose Subcutaneous TRIM65 0.10 0.07 lasso 4 0.05 3.0e-05 -5.6 -5.2 1.7e-07 0.60 0.82 0.11 FALSE
3 GTEx Adipose Subcutaneous MRPL38 0.08 0.07 lasso 4 0.06 9.3e-06 -5.6 5.7 1.0e-08 -0.78 0.58 0.40 FALSE
4 GTEx Brain Cerebellum TRIM65 0.34 0.14 enet 8 0.19 2.8e-06 -4.9 -5.5 3.8e-08 0.60 0.08 0.71 FALSE
5 GTEx Brain Cortex TRIM65 0.36 0.15 enet 22 0.24 3.7e-07 -5.0 -5.4 6.1e-08 0.72 0.06 0.91 FALSE
6 GTEx Brain Cortex FBF1 0.34 0.25 lasso 3 0.25 1.5e-07 -5.6 -5.3 9.0e-08 0.62 0.38 0.54 FALSE
7 GTEx Brain Hypothalamus TRIM65 0.26 0.09 lasso 7 0.12 9.7e-04 -2.8 -5.1 2.9e-07 0.79 0.03 0.65 FALSE
8 GTEx Brain Nucleus accumbens basal ganglia FBF1 0.29 0.32 lasso 2 0.29 1.9e-08 -5.6 -5.6 2.1e-08 0.56 0.57 0.20 FALSE
9 GTEx Esophagus Gastroesophageal Junction FBF1 0.33 0.16 lasso 6 0.13 2.3e-05 -5.6 -5.3 1.4e-07 0.58 0.56 0.11 FALSE
10 GTEx Heart Atrial Appendage FBF1 0.20 0.11 lasso 3 0.15 2.6e-07 -4.7 -6.1 1.1e-09 0.62 0.12 0.40 FALSE
11 GTEx Liver GALK1 0.35 0.16 lasso 9 0.24 2.6e-07 -3.2 -5.5 2.9e-08 0.86 0.01 0.98 FALSE
12 GTEx Nerve Tibial MRPL38 0.14 0.10 lasso 3 0.11 2.9e-08 -4.9 5.4 6.5e-08 -0.65 0.99 0.01 FALSE
13 GTEx Stomach FBF1 0.28 0.17 enet 12 0.17 1.5e-08 -4.7 -5.9 2.8e-09 0.74 0.44 0.55 FALSE
14 GTEx Thyroid WBP2 0.07 0.06 lasso 2 0.06 4.1e-05 -6.8 -6.7 1.9e-11 0.89 0.01 0.98 TRUE
15 GTEx Thyroid TRIM65 0.19 0.11 lasso 2 0.09 3.5e-07 -4.7 -5.3 1.4e-07 0.59 0.96 0.03 FALSE
16 GTEx Thyroid MRPL38 0.15 0.07 lasso 3 0.09 1.1e-07 -4.5 5.3 1.4e-07 -0.63 0.96 0.03 FALSE
17 METSIM Adipose FBF1 0.20 0.09 enet 41 0.12 2.5e-17 -4.7 -6.2 5.7e-10 0.47 0.97 0.03 FALSE
18 The Cancer Genome Atlas Glioblastoma Multiforme GALK1 0.15 0.04 blup 28 0.06 5.9e-03 -5.7 -6.1 1.4e-09 0.81 0.00 0.48 FALSE