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chr17:73,059,836-75,194,387

Best TWAS P=1.93e-11 · Best GWAS P=3.47e-12 conditioned to 0.0349

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RHBDF2	0.21	0.17	lasso	4	0.16	8.0e-13	5.2	5.2	2.5e-07	-0.01	0.97	0.03	TRUE
2	GTEx	Adipose Subcutaneous	TRIM65	0.10	0.07	lasso	4	0.05	3.0e-05	-5.6	-5.2	1.7e-07	0.60	0.82	0.11	FALSE
3	GTEx	Adipose Subcutaneous	MRPL38	0.08	0.07	lasso	4	0.06	9.3e-06	-5.6	5.7	1.0e-08	-0.78	0.58	0.40	FALSE
4	GTEx	Brain Cerebellum	TRIM65	0.34	0.14	enet	8	0.19	2.8e-06	-4.9	-5.5	3.8e-08	0.60	0.08	0.71	FALSE
5	GTEx	Brain Cortex	TRIM65	0.36	0.15	enet	22	0.24	3.7e-07	-5.0	-5.4	6.1e-08	0.72	0.06	0.91	FALSE
6	GTEx	Brain Cortex	FBF1	0.34	0.25	lasso	3	0.25	1.5e-07	-5.6	-5.3	9.0e-08	0.62	0.38	0.54	FALSE
7	GTEx	Brain Hypothalamus	TRIM65	0.26	0.09	lasso	7	0.12	9.7e-04	-2.8	-5.1	2.9e-07	0.79	0.03	0.65	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	FBF1	0.29	0.32	lasso	2	0.29	1.9e-08	-5.6	-5.6	2.1e-08	0.56	0.57	0.20	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	FBF1	0.33	0.16	lasso	6	0.13	2.3e-05	-5.6	-5.3	1.4e-07	0.58	0.56	0.11	FALSE
10	GTEx	Heart Atrial Appendage	FBF1	0.20	0.11	lasso	3	0.15	2.6e-07	-4.7	-6.1	1.1e-09	0.62	0.12	0.40	FALSE
11	GTEx	Liver	GALK1	0.35	0.16	lasso	9	0.24	2.6e-07	-3.2	-5.5	2.9e-08	0.86	0.01	0.98	FALSE
12	GTEx	Nerve Tibial	MRPL38	0.14	0.10	lasso	3	0.11	2.9e-08	-4.9	5.4	6.5e-08	-0.65	0.99	0.01	FALSE
13	GTEx	Stomach	FBF1	0.28	0.17	enet	12	0.17	1.5e-08	-4.7	-5.9	2.8e-09	0.74	0.44	0.55	FALSE
14	GTEx	Thyroid	WBP2	0.07	0.06	lasso	2	0.06	4.1e-05	-6.8	-6.7	1.9e-11	0.89	0.01	0.98	TRUE
15	GTEx	Thyroid	TRIM65	0.19	0.11	lasso	2	0.09	3.5e-07	-4.7	-5.3	1.4e-07	0.59	0.96	0.03	FALSE
16	GTEx	Thyroid	MRPL38	0.15	0.07	lasso	3	0.09	1.1e-07	-4.5	5.3	1.4e-07	-0.63	0.96	0.03	FALSE
17	METSIM	Adipose	FBF1	0.20	0.09	enet	41	0.12	2.5e-17	-4.7	-6.2	5.7e-10	0.47	0.97	0.03	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	GALK1	0.15	0.04	blup	28	0.06	5.9e-03	-5.7	-6.1	1.4e-09	0.81	0.00	0.48	FALSE