Hub : Genes

MALT1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1200	0.0439	4.0e-03	0.079	NA	0.051	NA	0.055	8.6e-07	NA	7.2e-05	NA	4.1e-05
2	GTEx	Brain Cerebellum	0.3230	0.1140	3.1e-03	-0.002	NA	0.039	NA	0.015	3.8e-01	NA	2.6e-02	NA	1.1e-01
3	GTEx	Muscle Skeletal	0.1058	0.0314	4.8e-04	0.038	NA	0.023	NA	0.040	1.2e-04	NA	2.2e-03	NA	7.4e-05
4	GTEx	Nerve Tibial	0.1471	0.0465	7.4e-04	0.086	NA	0.044	NA	0.073	1.1e-06	NA	4.2e-04	NA	6.9e-06
5	METSIM	Adipose	0.1118	0.0284	6.9e-07	0.058	0.051	0.085	0.075	0.066	4.0e-09	3.5e-08	1.2e-12	2.2e-11	3.3e-10
6	YFS	Blood	0.0949	0.0178	0.0e+00	0.089	0.064	0.088	0.092	0.090	1.4e-27	4.7e-20	2.3e-27	2.0e-28	4.9e-28
7	TCGA	Esophageal Carcinoma	0.2060	0.1080	3.5e-03	0.018	0.051	0.039	NA	0.040	8.5e-02	9.9e-03	2.2e-02	NA	2.1e-02
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.1586	0.0643	9.2e-06	0.026	0.033	0.032	NA	0.015	5.1e-04	1.3e-04	1.4e-04	NA	7.2e-03
9	TCGA	Brain Lower Grade Glioma	0.0418	0.0221	6.1e-04	0.051	0.031	0.043	NA	0.047	1.9e-06	1.5e-04	1.0e-05	NA	4.6e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.0	1.6	4.5	1.3	0.1	1.2	0.7	0.3	-0.0	2.1	1.8	1.5
Bipolar Disorder or Schizophrenia	0.4	1.0	3.7	0.7	-1.4	1.0	0.3	0.5	-0.9	1.9	0.9	0.5
Depressed Affect (Nagel 2018)	0.2	0.3	2.1	-0.5	0.1	0.1	-0.0	-0.4	-1.5	0.5	-0.2	0.2
Depression (Nagel 2018)	0.4	0.5	2.4	0.5	-1.6	1.0	0.5	-0.6	-0.8	-0.4	-0.0	0.1
Intelligence (Savage-Jansen 2018)	1.0	3.1	11.7	1.5	1.1	1.8	1.6	0.8	-1.8	3.4	1.2	1.2
Neuroticism (Nagel 2018)	0.2	0.4	1.3	0.4	1.2	0.5	0.7	-0.0	-0.9	-0.3	0.3	0.7
Schizophrenia (2018)	0.3	0.7	3.5	-0.2	-1.9	0.3	-0.2	0.4	-1.1	0.8	-0.3	-0.6
Schizophrenia vs Biploar Disorder	1.0	1.3	4.6	-0.1	1.1	0.0	-0.3	2.1	1.1	-2.1	-0.5	-0.3
Worry (Nagel 2018)	0.8	1.7	3.7	1.3	1.3	1.3	1.5	0.2	-1.9	1.6	0.7	1.1
Alzheimer’s Disease (in mother)	2.5	2.9	7.7	1.4	1.6	1.6	1.6	0.9	2.8	-1.0	2.1	1.5
Alzheimer’s Disease (in father)	1.4	1.5	2.9	1.7	-0.6	1.6	1.3	0.5	1.2	-0.8	1.3	1.4
Alzheimer’s Disease (including proxy)	3.2	4.6	9.8	2.2	1.6	2.6	2.0	0.9	3.1	-1.5	2.4	2.2
Crohns Disease (2017)	0.3	0.7	2.4	0.7	0.3	-0.2	0.4	-0.3	-1.6	1.6	0.1	0.4
Irritable Bowel Disease (IBD)	0.6	1.5	4.9	1.5	0.7	1.0	1.1	-1.0	-0.3	2.2	0.9	1.2
Ulcerative Colitis (UC)	1.2	2.2	3.5	1.7	0.7	1.8	1.4	-1.6	0.9	1.9	1.5	1.4
Major Depression (MDD)	0.9	1.1	3.6	-0.8	-0.3	-0.6	-0.6	-1.9	-1.6	0.4	-1.2	-1.0
Reaction Time	0.1	0.2	0.6	-0.0	-0.7	-0.7	-0.3	0.0	-0.6	0.2	0.5	0.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	5.6	0.4	0.1	1.0	0.4	-0.7	-1.1	2.4	0.6	0.2
Breast Cancer	0.5	1.1	1.9	1.3	0.8	0.7	1.2	1.4	1.1	-0.6	1.1	1.1
Ovarian Cancer	0.2	0.3	1.9	-0.1	-0.4	0.2	0.3	1.4	-0.1	0.5	-0.2	0.2
Prostate Cancer	0.6	0.8	4.8	0.3	0.1	0.6	0.0	-2.2	1.0	0.8	-0.0	0.1
Age at First Birth	0.3	0.4	2.1	0.4	-0.1	0.4	0.3	1.5	0.5	0.3	0.8	0.6
Bipolar Disorder (2011)	0.6	0.6	1.2	-0.4	-1.1	-0.6	-0.6	-0.7	-1.0	-0.2	-1.1	-0.4
Body Mass Index (BMI) (2010)	1.0	1.3	4.9	-1.0	-2.2	-0.6	-0.5	-1.3	-1.4	0.4	-1.0	-0.9
Coronary Artery Disease (CAD)	3.3	3.9	5.6	-1.7	-2.1	-2.1	-1.9	-1.5	-2.4	-1.8	-2.3	-2.0
Crohns Disease (2012)	0.3	0.4	1.7	0.1	0.1	-0.4	-0.4	-0.6	-1.3	1.1	0.2	-0.2
Mean Putamen Volume	0.6	0.7	1.4	1.0	0.6	0.8	0.7	1.1	0.4	0.4	1.2	0.8
Fasting Glucose	0.7	0.8	3.7	0.0	-0.7	-0.2	0.3	-1.2	-1.9	1.2	0.3	-0.2
HbA1C	1.4	1.5	4.4	-1.2	-1.1	-1.0	-0.8	-2.1	1.3	-0.4	-1.3	-1.3
HDL Cholesterol	0.5	0.9	2.0	1.2	0.3	1.2	1.2	-0.2	-0.0	0.5	1.4	1.2
LDL Cholesterol	0.6	0.9	1.4	1.2	0.9	0.8	0.8	-0.2	-0.8	1.2	1.2	1.1
Lupus	1.4	2.1	5.0	-1.4	-2.2	-0.8	-0.9	-1.8	-2.2	1.2	-0.2	-1.2
Neuroticism (2016)	0.5	0.7	1.3	-1.1	-0.0	-0.9	-0.8	0.5	-1.2	-0.7	-0.7	-1.1
Primary Biliary Cirrhosis	1.7	2.4	8.0	-1.4	-1.1	-1.4	-1.8	-0.6	-2.8	1.0	-1.4	-1.3
Rheumatoid Arthritis	0.5	0.7	2.9	0.4	-0.1	0.3	0.3	-1.6	-0.4	1.7	0.4	0.7
Schizophrenia (2014)	0.1	0.2	0.9	0.2	-1.0	0.5	-0.1	0.5	-0.0	0.5	-0.0	-0.3
Triglycerides	1.6	2.5	4.3	-2.1	-1.4	-1.7	-2.0	-0.7	0.2	-1.8	-1.6	-1.8
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.1	-0.4	-0.4	-0.3	-0.2	1.2	-0.9	-0.9	-1.4	-0.3
Ulcerative Colitis	0.5	0.8	2.5	0.8	-0.1	0.8	0.4	-1.6	-0.4	1.6	0.4	0.5
Blood Eosinophil Count	3.4	26.1	45.6	6.8	4.9	6.5	6.3	0.8	1.4	4.5	4.3	6.4
Blood Platelet Count	0.0	0.4	2.0	-0.6	0.6	-0.3	-0.6	0.1	-0.1	0.0	-1.4	-0.5
Blood Red Count	0.1	1.1	6.2	-0.3	-0.6	-0.7	-0.9	0.5	1.1	-2.5	0.0	0.1
Blood White Count	0.1	0.6	5.0	0.4	-0.3	0.3	-0.2	2.2	0.0	-0.3	0.2	0.4
Heel T-Score	0.2	1.7	4.0	-1.2	-0.7	-1.3	-1.0	-2.0	1.1	-2.0	-0.4	-1.3
BMI	0.3	1.9	11.4	-0.6	-1.7	-0.6	-0.1	-1.0	-3.4	0.4	-0.4	-0.7
Height	0.0	0.9	1.8	-1.2	-0.1	-1.1	-0.9	0.5	-1.4	-1.2	-0.9	-0.9
Waist Hip Ratio (WHR)	0.4	1.8	3.2	1.5	-0.0	1.8	1.2	1.6	1.3	0.7	1.7	1.3
Systolic Blood Pressure	0.6	2.8	5.7	-2.4	-0.7	-1.6	-1.8	-1.2	-1.3	-0.3	-2.3	-2.1
Smoking Status	0.3	0.7	2.8	0.2	0.6	0.4	0.4	0.5	-1.6	1.7	-0.1	0.1
Allergy or Eczema	0.7	2.0	4.1	1.7	1.6	1.8	1.9	0.1	-0.2	1.1	0.2	2.0
Cardiovascular Disease	0.2	0.8	1.5	-1.2	1.0	-1.0	-0.7	-0.2	-0.4	-1.1	-1.0	-0.7
Hypothyroidism (self reported)	0.2	0.4	1.0	-0.7	-0.9	-1.0	-0.7	0.2	-0.3	-0.1	-0.8	-0.5
Respiratory disease	0.2	0.5	1.5	-0.5	0.9	-0.2	-0.3	0.4	-0.6	0.9	-1.2	-0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	3.8	-0.6	0.7	-0.7	-0.6	0.2	0.2	-0.9	-2.0	-0.9
Lung FEV1/FVC ratio	0.2	0.9	5.3	-0.7	-1.2	0.0	0.0	0.1	-2.3	0.0	-0.2	-0.7
Lung FVC	0.7	3.4	6.8	2.4	1.8	2.3	2.6	1.5	-0.0	1.5	1.1	2.0
Neuroticism	0.2	0.4	2.5	0.1	1.0	0.5	0.0	-0.0	-1.6	0.0	-0.4	-0.1
Chronotype (morning person)	0.1	0.2	0.5	0.7	-0.2	0.3	0.6	0.7	0.3	-0.1	0.0	0.6
Hair Pigment	0.0	0.8	3.3	-0.8	0.2	-0.7	-0.3	-1.8	-0.7	1.1	-0.9	-0.3
Tanning	0.1	1.1	2.5	1.4	1.6	1.3	1.2	-0.1	0.7	-0.4	-0.5	1.2
Hand grip strength (left)	0.2	0.6	1.3	-0.6	-1.1	-0.9	-0.8	-0.9	-0.5	-0.7	-0.1	-1.0
Number of treatments/medications taken	0.2	0.3	1.4	0.4	1.2	0.5	0.6	-0.1	-0.3	0.6	-0.2	0.6
Average weekly spirits intake	0.3	0.4	1.1	0.1	-0.4	0.6	0.5	1.1	0.7	0.1	0.8	0.5
Sensitivity / hurt feelings	0.4	0.6	4.0	-0.2	0.2	0.1	-0.2	-0.1	1.0	-2.0	0.7	-0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.5	0.5	-0.3	0.7	0.3	-0.2	-0.5	-0.4	0.3	-0.1
Hearing difficulty/problems: Yes	1.9	2.9	7.2	-1.9	-1.7	-1.9	-2.1	-0.2	0.7	-2.7	-1.0	-1.7
Relative age of first facial hair	3.2	6.6	9.6	3.0	3.1	2.8	2.7	2.2	0.8	2.0	2.7	3.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.6	0.4	0.4	0.0	0.8	0.0	-0.2	-0.5	-0.2	0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.9	0.1	0.8	0.0	0.1	0.6	0.7	-1.0	0.4	0.6
Ever had hysterectomy (womb removed)	0.4	0.4	0.9	0.7	-0.3	0.8	0.6	-0.3	0.5	0.7	1.0	0.7
Systolic blood pressure, automated reading	0.3	0.8	1.6	-1.1	-0.7	-0.1	-1.1	-0.5	-0.7	1.3	-0.7	-1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.3	-0.3	1.1	-0.1	-0.3	-0.8	0.4	-0.8	-0.8	-0.7
Angina	0.4	0.5	2.4	0.5	0.5	0.5	0.3	0.1	1.5	-0.9	0.2	0.5
Medication for hormone replacement therapy	0.1	0.1	0.4	-0.3	0.1	0.2	-0.4	-0.2	-0.6	0.1	0.1	-0.2
Vitamin and mineral supplements	0.7	1.0	3.7	-0.5	-0.2	-0.8	-1.0	0.4	1.5	-1.9	-0.8	-0.7
Supplements: Zinc	0.2	0.2	1.2	0.0	0.4	-0.1	-0.1	-0.0	-1.1	0.5	-0.1	0.6
Medication: Co-codamol	0.4	0.5	2.5	0.3	1.6	0.5	0.9	-0.4	-0.2	0.3	0.2	0.4
Medication: Metformin	2.7	3.8	9.0	-2.3	-0.6	-2.1	-2.1	-0.8	0.2	-1.9	-3.0	-2.3
Diabetes (father)	0.3	0.4	2.1	-0.7	0.2	-0.6	-0.4	0.1	0.0	-1.4	-0.6	-0.6
Diabetes (mother)	0.3	0.4	1.2	0.3	-1.1	-0.3	0.5	-0.3	-0.0	1.0	-1.0	-0.2
Severe depression (siblings)	1.5	1.7	4.1	-1.3	-0.6	-1.0	-1.1	-2.0	-2.0	0.2	-1.3	-1.2
Pack years adult smoking proportion	0.2	0.4	2.1	-0.4	0.6	-0.2	-0.3	0.7	-1.5	-0.3	-0.1	0.0
Impedance of leg (right)	0.7	3.2	5.3	1.7	2.3	1.7	1.3	1.7	2.2	0.8	2.2	1.7
Leg fat-free mass (left)	0.6	3.2	15.9	-1.2	-2.4	-1.3	-0.6	-0.6	-4.0	0.2	-1.2	-1.2
Trunk fat percentage	0.4	1.5	9.7	-0.3	-1.7	-0.5	-0.0	-0.2	-3.1	0.2	-0.3	-0.4
Hand grip strength (right)	0.4	1.0	2.3	-0.6	-1.5	-1.0	-0.7	-1.2	-1.1	-0.5	0.1	-1.3
Townsend deprivation index at recruitment	0.9	1.3	3.7	1.2	1.9	1.2	0.9	-0.6	0.2	1.5	0.4	1.0
Current tobacco smoking	0.2	0.3	0.8	-0.5	0.3	-0.5	-0.8	0.9	-0.9	-0.1	-0.3	-0.5
Average weekly fortified wine intake	0.3	0.4	2.1	-0.1	0.4	0.4	0.1	0.4	1.4	-0.4	0.6	0.1
Maternal smoking around birth	0.6	0.8	2.1	1.1	0.2	1.0	1.1	-1.1	0.3	0.0	0.6	1.4
Fed-up feelings	0.5	0.8	1.7	0.9	0.5	1.3	1.2	-0.3	-0.1	0.8	1.0	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.5	-0.1	-1.2	0.4	-0.2	0.4	0.2	-0.7	0.3	-0.3
Relative age voice broke	2.6	4.0	6.4	2.3	2.5	2.3	2.3	-0.2	1.2	1.8	2.2	2.1
Taking other prescription medications	0.1	0.2	0.9	0.2	-0.4	0.2	0.3	0.0	-0.9	0.6	-0.1	0.2
Age when periods started (menarche)	0.3	0.7	2.0	0.4	1.4	0.8	0.5	0.4	-1.0	0.3	1.3	0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.0	-0.6	-1.4	-0.4	-0.4	0.2	-0.5	0.4	-0.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.0	-1.0	0.0	-0.8	-0.8	-0.8	-1.1	-0.3	0.2	-1.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.3	0.3	-0.1	0.1	0.2	1.1	0.9	-0.2	-0.3	0.6
Qualifications: CSEs or equivalent	0.4	0.5	1.3	0.6	0.5	0.5	0.9	0.9	-1.0	0.0	0.2	1.1
Serious illness, injury or assault to yourself	0.7	0.9	2.7	-0.5	0.1	-0.7	-0.3	0.7	-1.6	1.5	-1.0	-1.0
High blood pressure	0.4	1.1	2.7	-1.1	1.5	-0.7	-1.0	0.7	0.9	-1.6	-1.0	-0.6
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.5	1.5	1.5	1.5	1.9	-0.2	-0.9	0.7	-0.1	1.7
Multivitamins +/- minerals	0.5	0.6	1.4	0.8	-0.3	0.9	1.2	-0.0	-1.0	0.6	0.9	0.6
Stomach or abdominal pain in last month	1.1	1.3	4.0	-0.9	-2.0	-0.9	-1.0	1.5	-1.3	0.0	-0.2	-1.0
Supplements: Glucosamine	0.3	0.4	2.0	0.0	-1.4	-0.4	0.4	0.2	-1.0	-0.3	-0.3	-0.1
Diverticular disease/diverticulitis (self-reported)	2.6	3.1	6.7	2.0	2.6	1.9	1.6	-0.1	1.7	0.5	2.0	2.0
Medication: Atenolol	0.1	0.2	0.6	-0.3	0.6	0.1	0.1	0.3	0.4	-0.7	-0.8	0.1
Medication: Levothyroxine sodium	0.7	1.1	2.8	-1.3	-1.2	-1.7	-1.2	-0.4	-0.1	-0.8	-0.9	-1.0
Sitting height	0.2	1.7	5.3	-1.1	-1.8	-1.2	-0.8	1.0	-2.3	0.4	-0.2	-1.3
Chronic bronchitis/emphysema (father)	0.6	0.7	2.2	0.6	1.5	0.7	0.8	-1.2	0.5	-0.1	-0.1	1.0
High blood pressure (mother)	0.1	0.1	0.3	-0.2	-0.6	0.1	0.3	-0.1	0.3	0.5	0.1	0.3
Body mass index (BMI)	0.7	2.9	10.2	-1.3	-2.6	-1.5	-0.9	-0.9	-3.2	-0.1	-1.3	-1.3
Impedance of leg (left)	0.3	1.4	4.8	0.9	1.7	1.0	0.5	1.2	2.2	-0.1	1.2	0.8
Leg predicted mass (left)	0.6	3.4	16.4	-1.3	-2.4	-1.4	-0.8	-0.6	-4.0	0.2	-1.3	-1.3
Trunk fat mass	0.5	2.3	12.2	-0.8	-2.2	-1.0	-0.5	-0.4	-3.5	0.1	-0.7	-0.9
Waist circumference	0.7	2.7	7.9	-1.3	-2.8	-1.3	-1.0	-0.9	-2.7	-0.5	-1.2	-1.4
Number of incorrect matches in round	1.7	2.9	7.1	2.1	1.0	1.3	1.6	2.7	0.8	0.2	1.5	2.4
Past tobacco smoking	1.0	1.8	4.6	-1.3	-1.4	-1.4	-1.1	-0.5	-0.5	-2.1	-1.5	-1.4
Alcohol usually taken with meals	0.5	0.9	1.9	-1.4	0.1	-1.2	-1.1	-0.4	-1.2	-0.2	-0.8	-1.0
Nervous feelings	0.2	0.4	1.9	-0.2	1.0	-0.2	-0.1	0.3	-1.4	-0.1	-0.3	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.4	-1.1	-1.7	-0.6	-0.7	-1.1	-1.8	0.1	-0.2	-1.3
Hearing difficulty/problems with background noise	0.3	0.5	1.4	-0.7	-0.5	-0.7	-0.7	-0.5	0.4	-1.2	-0.7	-0.4
Hair/balding pattern: Pattern 2	0.2	0.3	1.9	-0.1	0.4	-0.3	0.0	0.6	0.4	-1.4	-0.1	0.3
Had menopause	1.8	2.3	5.5	1.7	-1.0	1.6	1.0	0.9	1.2	2.0	2.4	1.3
Had other major operations	0.3	0.3	1.7	-0.4	-0.3	-0.5	-0.2	-0.2	-1.3	0.4	-0.6	-0.3
Forced vital capacity (FVC)	0.3	1.1	3.1	1.3	0.8	1.1	1.8	1.3	-0.8	0.3	0.0	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.4	-0.7	0.2	-0.5	-0.4	-0.9	-1.1	-0.1	0.0	-1.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.7	0.3	-1.3	0.0	0.2	0.9	0.0	-0.3	0.8	-0.3
Qualifications: None of the above	0.4	0.8	1.5	1.1	0.6	1.2	1.2	0.3	1.0	0.5	0.5	1.2
Financial difficulties in last 2 years	0.7	0.9	2.6	0.9	0.6	1.0	1.3	1.6	-0.4	-0.6	0.6	1.0
Mouth/teeth dental problems	0.6	1.0	4.7	-0.1	-1.0	-0.2	0.2	-2.2	1.1	-1.1	0.6	-0.3
Heart attack	0.5	0.6	1.8	0.9	-0.1	1.4	1.0	0.0	0.9	-0.4	0.5	0.6
Allergy	1.0	2.2	4.8	-1.6	-2.1	-1.6	-2.2	0.1	1.1	-0.8	0.3	-1.9
Pain all over the body in last month	2.1	2.2	4.2	1.6	1.5	1.7	2.0	0.9	-0.6	2.0	0.9	1.6
Diabetes (self-reported)	1.3	2.0	7.2	-1.4	-0.3	-1.2	-1.4	0.2	0.6	-1.6	-2.7	-1.6
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	4.4	1.7	0.9	1.4	2.1	1.0	1.3	-0.5	1.0	1.8
Medication: Ramipril	0.2	0.2	0.8	0.2	0.1	0.6	0.6	0.9	-0.1	0.0	-0.4	0.3
Medication: Simvastatin	0.5	0.7	1.8	-0.6	0.1	-0.5	-0.5	0.4	1.1	-1.3	-1.2	-1.0
Fluid intelligence score	0.5	1.1	2.9	-1.0	-0.9	-0.9	-1.0	-0.5	-1.7	1.0	-0.3	-1.4
Illnesses of siblings	1.1	1.5	2.9	1.7	0.2	1.3	0.9	1.3	-0.7	1.4	1.5	1.3
Neuroticism score	0.2	0.4	1.6	0.5	0.8	0.7	0.5	-0.3	-1.3	0.1	0.1	0.1
Weight	0.8	4.0	14.7	-1.6	-3.0	-1.8	-1.2	-0.6	-3.8	-0.2	-1.3	-1.7
Impedance of arm (right)	0.5	2.1	3.6	1.5	1.6	1.9	1.3	1.3	1.1	0.5	1.5	1.8
Arm fat percentage (right)	0.4	1.6	9.4	-0.4	-1.9	-0.5	-0.2	-0.4	-3.1	0.8	-0.5	-0.4
Trunk fat-free mass	0.5	3.1	9.0	-1.7	-2.4	-1.8	-1.4	-0.1	-3.0	0.2	-1.2	-1.9
Hip circumference	0.9	3.7	13.1	-1.5	-2.8	-1.6	-1.0	-1.4	-3.6	-0.4	-1.3	-1.6
Time employed in main current job	0.9	1.0	2.0	1.4	1.2	1.2	0.7	-0.6	-0.5	1.3	0.3	1.2
Alcohol intake versus 10 years previously	1.5	2.3	5.7	1.5	2.4	1.4	1.7	1.2	-0.7	2.0	0.1	1.3
Father’s age at death	0.2	0.2	0.9	0.9	-0.3	0.0	0.5	-0.0	-0.1	-0.5	0.0	0.8
Worrier / anxious feelings	1.3	2.5	5.6	2.0	1.3	1.8	2.4	0.5	-0.8	1.0	1.4	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	3.5	0.1	-0.1	0.1	0.5	1.0	-0.5	-1.9	-0.6	0.0
Falls in the last year	0.2	0.3	1.5	0.1	-0.8	0.1	0.1	-0.1	0.1	-0.5	1.2	0.1
Hair/balding pattern: Pattern 3	0.3	0.5	3.0	-0.2	-1.7	0.1	-0.2	-0.3	-0.6	0.1	-0.7	-0.6
Number of live births	2.9	4.0	12.8	2.2	1.3	2.2	1.5	1.5	3.6	-0.5	1.8	2.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	2.0	0.1	-0.4	0.0	0.6	1.4	-1.2	-0.7	-0.7	-0.0
Pulse rate	1.1	1.9	4.5	-1.5	-1.3	-1.3	-1.5	1.1	-2.1	0.2	-1.6	-1.1
Happiness	0.7	0.8	2.5	-0.4	-1.5	-1.0	-0.4	-0.4	-1.6	-0.2	0.7	-0.7
Noisy workplace	0.3	0.4	1.0	0.6	1.0	-0.2	0.5	-0.4	-0.5	0.6	-0.0	1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.6	3.2	-1.3	-0.6	-1.5	-1.8	-1.7	-1.0	-0.3	-0.5	-1.6
Serious illness, injury or assault of a close relative in last 2 years	4.2	4.8	8.6	-2.3	-2.9	-2.4	-2.6	-0.5	-0.7	-2.9	-1.5	-2.3
Mouth/teeth dental problems: Dentures	1.2	2.0	5.2	1.1	1.9	1.4	0.6	1.5	-0.4	2.3	1.4	1.3
Asthma	0.2	0.5	2.8	0.6	1.7	0.5	0.7	-0.1	-0.0	0.2	-0.6	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.6	0.1	0.1	-0.4	0.6	1.2	-0.7	1.3	-0.0	0.4
Medication: Cholesterol lowering	0.4	0.6	2.6	-0.4	-0.0	-0.1	-0.5	-0.4	1.0	-1.2	-1.6	-0.4
Depression (self-reported)	0.9	1.0	4.4	-0.3	-1.6	0.3	-0.6	-0.4	0.6	-1.1	2.1	-0.4
Medication: Lansoprazole	0.9	1.0	2.7	1.0	0.9	1.1	0.9	1.6	0.7	-0.4	0.9	1.0
Prospective memory result	0.1	0.2	1.1	-0.1	0.4	0.4	-0.0	-0.1	0.1	1.1	0.3	-0.1
Lung cancer (father)	5.3	6.2	9.7	2.5	1.8	2.9	3.1	0.5	0.6	3.1	2.9	3.1
Illnesses of mother	0.3	0.3	2.0	-0.1	0.5	-0.2	-0.5	0.2	-1.4	-0.5	-0.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.9	0.3	-0.4	-0.0	0.8	1.0	-1.4	-0.5	-0.5	-0.0
Pulse wave Arterial Stiffness index	0.4	0.5	2.9	0.1	0.1	-0.1	-0.4	0.5	-1.7	1.1	0.2	0.2
Impedance of arm (left)	0.2	1.1	2.2	1.0	1.5	1.0	0.7	1.0	1.3	-0.3	0.8	1.3
Arm fat mass (right)	0.7	3.0	13.5	-1.1	-2.6	-1.3	-0.8	-0.5	-3.7	0.4	-1.0	-1.1
Trunk predicted mass	0.5	3.1	8.5	-1.7	-2.5	-1.8	-1.4	-0.1	-2.9	0.2	-1.2	-1.9
Standing height	0.1	1.0	5.0	-0.8	-1.0	-0.7	-0.8	0.6	-2.2	0.2	-0.3	-1.0
Length of working week for main job	0.6	0.7	2.0	-0.1	-0.5	-0.3	0.2	-1.4	-1.4	1.3	-0.4	0.1
Exposure to tobacco smoke at home	0.6	0.6	1.4	0.9	0.4	0.7	0.7	-0.3	0.6	0.5	1.2	1.2
Breastfed as a baby	1.8	2.2	7.2	1.0	1.0	1.7	1.1	1.7	-1.5	2.7	0.7	1.0
Tense / ‘highly strung’	1.5	2.5	4.5	1.3	1.5	1.5	1.7	0.6	-1.9	2.1	2.0	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.0	0.8	0.0	0.8	1.0	-0.3	-0.4	0.4	0.7	0.6
Hair/balding pattern: Pattern 4	0.4	0.9	1.7	-1.3	-0.2	-0.8	-1.0	-1.2	-1.0	0.3	-1.2	-0.9
Birth weight of first child	1.4	2.5	6.2	-1.6	-2.5	-1.5	-2.1	-0.9	0.5	-1.0	-1.2	-1.9
Peak expiratory flow (PEF)	1.0	2.3	3.8	-1.8	-1.4	-1.9	-1.2	-0.8	-1.9	-0.8	-1.9	-1.4
Pulse wave reflection index	0.5	0.6	2.8	0.7	0.7	0.7	0.5	0.6	-0.1	0.4	1.7	0.5
Ever highly irritable/argumentative for 2 days	0.7	0.9	1.5	-1.0	-1.2	-1.2	-0.6	0.8	-0.7	-0.7	-1.1	-0.8
Loud music exposure frequency	0.3	0.3	1.1	0.2	-0.5	0.4	0.3	1.0	-0.8	-0.2	0.6	0.3
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.7	-0.9	-0.3	-1.1	-1.1	-1.3	-0.2	-1.0	-0.3	-1.0
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.2	0.3	-0.3	0.3	0.4	0.2	0.1	0.1	-0.2	0.4
Blood clot in the leg (DVT)	0.6	0.8	2.1	1.2	0.5	0.7	1.5	0.7	0.5	-0.2	0.6	1.3
Medication: Paracetamol	4.5	7.4	11.3	3.0	2.7	2.9	2.9	3.4	-1.9	2.3	2.1	2.9
Headache pain in last month	0.3	0.5	1.5	-0.8	-0.3	-0.8	-0.3	0.5	-0.9	-0.0	-1.2	-0.3
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	3.4	1.0	-0.6	0.4	1.1	1.0	-1.0	1.0	1.8	0.7
Glaucoma (self-reported)	0.4	0.5	1.4	0.6	0.7	0.0	0.2	1.2	0.1	-1.2	0.6	0.5
Gout (self-reported)	1.4	1.9	3.6	-1.7	-1.9	-1.8	-1.6	-0.3	-1.1	-0.7	-0.5	-1.5
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.1	-1.0	-1.8	-1.3	-0.7	-0.7	-0.3	0.0	-1.1	-0.7
Medication: Amlodipine	0.6	0.8	3.7	-0.2	0.6	-0.1	-0.2	1.3	1.9	-1.0	-0.8	-0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.8	0.2	1.1	0.4	0.4	-1.3	0.7	0.5	-0.2	0.0
Birth weight	0.9	1.9	5.5	-1.8	-0.5	-1.7	-1.5	-0.6	-0.9	-1.0	-2.3	-1.2
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.1	0.1	-1.1	0.3	0.3	-0.1	-0.8	1.4	0.3	-0.0
High blood pressure (siblings)	0.9	1.2	2.8	-1.4	0.7	-1.2	-1.1	-0.5	0.9	-1.7	-1.1	-1.0
Forced vital capacity (FVC), Best measure	0.2	0.7	2.3	1.1	0.5	0.7	1.5	0.9	-0.7	-0.3	0.0	0.6
Body fat percentage	0.4	1.4	7.9	-0.4	-1.9	-0.6	-0.2	-0.3	-2.8	0.2	-0.4	-0.5
Leg fat percentage (right)	0.2	0.9	3.7	-0.3	-1.7	-0.7	-0.1	-0.6	-1.9	0.3	-0.1	-0.3
Arm fat-free mass (right)	0.6	3.1	8.6	-1.7	-2.2	-1.9	-1.5	-0.7	-2.9	-0.1	-1.2	-1.9
Exposure to tobacco smoke outside home	0.1	0.2	0.5	-0.1	0.5	-0.6	0.2	-0.7	0.2	-0.4	0.0	0.3
Comparative body size at age 10	0.1	0.3	0.9	0.5	0.5	-0.3	0.8	-0.9	-0.1	-0.8	-0.5	0.3
Number of full brothers	0.4	0.5	2.3	-0.8	0.1	-1.0	-0.1	-1.5	0.5	-0.5	-0.2	-0.4
Worry too long after embarrassment	0.5	0.8	2.6	-0.8	1.2	-0.8	-0.8	-0.3	-0.5	-1.6	-0.4	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.2	0.3	-0.2	0.4	0.3	-1.2	-0.8	0.1	1.5	-0.1
Wheeze or whistling in the chest in last year	0.3	0.5	2.5	-0.4	0.7	-0.7	-0.6	1.6	-0.0	-0.6	-0.7	-0.2
Number of children fathered	0.7	0.8	1.6	-1.3	-0.8	-1.1	-1.0	-0.6	0.0	-1.1	-1.0	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	5.1	-1.3	-0.3	-1.0	-1.1	-2.3	1.4	-1.5	-1.9	-1.0
Age at first live birth	0.2	0.4	1.6	-0.7	-0.5	-0.7	-0.9	-0.2	-1.3	-0.3	-0.2	-0.4
Pulse wave peak to peak time	0.4	0.5	2.5	-0.2	-0.2	-0.0	0.2	-0.2	1.6	-1.2	-0.3	-0.3
Health satisfaction	0.4	0.5	1.9	-0.2	-0.9	-0.7	-0.4	-0.4	-1.4	0.1	-0.5	-0.9
Shortness of breath walking on level ground	0.6	0.7	2.3	-0.7	-0.1	-1.0	-0.8	0.8	-0.7	-0.7	-1.5	-0.6
Qualifications: College or University degree	0.1	0.5	1.4	0.7	0.3	0.4	0.5	-1.0	-0.5	0.7	1.2	0.2
Eye problems/disorders: None of the above	0.6	0.7	3.2	-0.8	-1.8	-0.4	-0.4	-0.2	-0.4	0.1	-1.1	-0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	0.0	0.1	-0.2	0.1	1.0	-0.5	0.4	-0.6	-0.5
Emphysema/chronic bronchitis	0.6	0.7	1.8	-1.0	0.8	-0.5	-0.6	1.3	-0.8	0.2	-1.0	-0.7
Medication for pain relief, constipation, heartburn	1.0	1.8	4.0	-1.2	-1.0	-1.5	-1.6	-2.0	1.0	-1.0	-0.3	-1.6
Neck or shoulder pain in last month	0.1	0.1	0.5	-0.1	-0.2	-0.5	-0.3	0.7	-0.3	-0.0	-0.4	-0.2
Medication: Blood pressure	0.7	1.3	3.2	-1.2	0.3	-0.6	-1.2	0.2	1.8	-1.5	-1.5	-0.6
Angina (self-reported)	0.4	0.5	2.3	0.4	0.6	0.5	0.3	0.6	1.5	-1.0	0.2	0.5
Migraine (self-reported)	0.6	0.7	2.1	-0.9	-0.6	-0.7	-0.4	1.1	-0.7	1.4	-0.2	-0.6
Medication: Ibuprofen	0.4	0.5	1.4	-0.6	-0.4	-0.9	-0.1	0.8	-1.2	0.9	-0.3	-0.2
Medication: Allopurinol	2.8	3.7	6.0	-2.5	-1.9	-2.3	-1.6	-2.4	-2.1	-0.0	-1.1	-2.1
Medication: Omeprazole	0.4	0.4	1.4	-0.4	-1.2	0.1	0.3	-0.4	-0.6	0.4	-1.2	-0.4
Medication: Seretide 50 evohaler	1.5	1.8	2.9	-1.7	-1.4	-1.6	-1.6	-0.5	0.2	-0.7	-1.7	-1.6
Mean time to correctly identify matches	0.1	0.1	0.5	0.2	-0.7	-0.2	-0.1	0.1	0.4	-0.2	0.4	0.5
Heart disease (mother)	0.4	0.5	1.6	-0.6	-0.2	-1.0	-0.7	-0.3	1.3	-0.6	-0.2	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.6	8.2	-1.9	-1.5	-1.5	-1.8	-2.9	-0.4	-0.3	-0.6	-1.7
Whole body fat mass	0.6	2.7	12.2	-1.0	-2.6	-1.2	-0.7	-0.3	-3.5	-0.1	-1.0	-1.1
Leg fat mass (right)	0.6	2.5	9.1	-1.1	-2.5	-1.4	-0.8	-0.9	-3.0	-0.0	-1.0	-1.1
Arm predicted mass (right)	0.5	2.4	7.3	-1.5	-2.1	-1.6	-1.2	-0.5	-2.7	-0.1	-1.2	-1.6
Pulse rate, automated reading	0.6	2.0	4.8	-1.3	-2.2	-1.3	-1.3	0.6	-1.9	-0.2	-1.4	-1.4
Alcohol intake frequency.	0.3	0.6	1.7	0.7	0.8	-0.0	0.5	1.2	-1.3	0.4	-0.5	0.7
Comparative height size at age 10	0.2	1.0	1.5	1.1	0.7	1.2	1.2	0.8	-0.6	1.0	0.9	1.1
Number of full sisters	0.4	0.5	1.8	0.1	1.2	0.6	0.4	0.0	-0.6	1.4	-0.5	0.0
Suffer from ‘nerves’	0.1	0.2	0.5	0.6	0.7	0.5	0.5	-0.4	0.0	0.0	0.2	0.3
Overall health rating	0.2	0.5	1.2	0.4	1.0	0.5	1.1	0.8	0.3	-1.0	-0.3	0.3
Chest pain or discomfort	1.2	1.7	4.5	1.1	2.1	0.9	1.1	0.2	2.1	-0.9	1.3	1.2
Had major operations	0.5	0.5	1.1	0.9	0.3	0.8	0.5	1.0	0.7	-0.3	0.9	0.7
Age at last live birth	0.1	0.1	0.5	0.4	0.5	0.4	-0.2	0.1	-0.1	0.1	0.7	0.4
Family relationship satisfaction	0.4	0.4	1.5	0.7	0.2	0.2	0.4	0.9	0.9	-0.3	1.2	0.2
Leg pain on walking	1.6	2.0	4.6	-1.6	-0.7	-1.6	-1.5	-1.1	-1.2	-2.1	-1.1	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	4.2	0.1	0.2	-0.0	0.4	-2.0	0.2	0.2	-0.5	-0.1
Commuting to job workplace: Car/motor vehicle	5.2	5.9	10.4	-3.1	-0.9	-2.9	-2.6	-0.8	-1.7	-2.6	-3.2	-2.6
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	5.4	1.1	0.8	0.9	0.6	-1.1	2.3	-0.1	0.7	1.1
Medication: Aspirin	0.2	0.3	1.2	0.3	-0.4	0.4	0.2	0.3	0.6	-0.4	-1.1	0.3
Supplements: Vitamin C	0.8	0.9	3.1	-0.1	1.2	-0.3	0.5	-0.7	-1.4	1.8	0.7	0.6
Knee pain experienced in last month	0.5	0.8	1.4	1.0	0.5	1.1	0.8	0.8	1.0	-1.2	0.4	0.9
Hypertension (Self-reported)	0.3	0.9	2.2	-0.8	1.5	-0.5	-0.5	1.0	1.1	-1.5	-0.8	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	6.4	-1.0	-2.5	-1.2	-1.0	-1.2	1.0	-1.5	-0.5	-0.9
Illnesses of father: Heart disease	0.2	0.3	0.7	-0.4	0.2	-0.5	-0.8	-0.1	0.6	-0.7	-0.3	-0.7
Illnesses of siblings: Diabetes	2.3	2.8	7.9	-2.1	-0.8	-2.0	-1.0	-0.8	-0.4	-1.5	-2.8	-2.1
Smoking status: Previous	0.7	1.0	4.2	0.8	1.0	1.0	0.8	0.2	0.0	2.0	0.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.3	0.5	0.2	0.7	0.6	0.1	-1.5	1.2	-0.4	0.3
Whole body fat-free mass	0.6	3.4	12.1	-1.6	-2.5	-1.7	-1.2	-0.4	-3.5	0.1	-1.4	-1.8
Leg fat-free mass (right)	0.7	3.6	14.4	-1.6	-2.5	-1.6	-1.0	-0.9	-3.8	-0.3	-1.6	-1.5
Arm fat percentage (left)	0.5	2.1	9.5	-0.9	-2.2	-1.1	-0.7	-0.7	-3.1	0.2	-1.1	-0.8
Average weekly red wine intake	0.4	0.6	1.9	-0.9	-0.8	-0.7	-0.7	0.1	0.1	-1.4	-0.7	-0.6
Handedness (chirality/laterality): Left-handed	2.0	2.4	5.2	1.5	1.4	1.5	1.0	2.3	1.8	-0.4	1.7	1.7
Mood swings	0.1	0.2	0.4	0.0	0.6	-0.1	0.3	0.6	-0.4	0.2	0.6	0.6
Loneliness, isolation	0.1	0.1	0.3	0.1	-0.1	0.5	0.1	-0.5	-0.3	0.2	0.3	0.1
Long-standing illness, disability or infirmity	0.6	0.9	2.2	1.1	1.1	1.1	1.5	0.9	0.2	0.5	-0.0	1.2
Ever had bowel cancer screening	0.6	0.6	2.4	0.3	0.6	0.6	0.6	1.2	1.6	-0.7	-0.1	0.6
Diabetes diagnosed by doctor	2.0	3.3	9.0	-2.0	-0.8	-1.8	-2.0	-0.3	0.6	-1.8	-3.0	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	2.5	1.5	1.2	1.6	1.2	-0.9	-0.8	0.8	0.6	1.1
Friendships satisfaction	0.3	0.4	1.0	0.2	1.0	-0.4	-0.3	0.5	0.8	-0.3	0.8	-0.5
Qualifications: nursing, teaching	0.3	0.4	1.1	0.4	-0.8	0.4	-0.1	0.8	-1.1	0.2	1.0	0.4
Commuting to job workplace: Walk	1.7	1.9	4.2	1.4	1.5	1.6	1.2	0.3	2.0	1.3	1.2	1.2
Eye problems/disorders: Cataract	0.5	0.6	2.6	0.4	1.6	0.4	0.6	0.5	1.0	-0.6	0.4	0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.8	0.1	0.7	0.1	-0.0	1.3	0.5	-0.5	-0.0	0.5
Medication for cholesterol	0.2	0.3	1.1	0.1	-1.1	0.1	-0.0	-0.3	-0.4	0.9	0.4	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.8	1.8	0.2	2.2	2.2	1.0	-0.6	0.4	0.7	1.7
Back pain experienced in last month	0.7	1.1	5.6	-0.9	-0.1	-0.7	-1.1	0.8	-0.3	-2.4	-0.1	-1.0
Mineral and other dietary supplements	0.5	0.7	4.4	-0.1	0.7	0.4	-0.3	2.1	0.7	0.1	0.9	0.3
Breast cancer (self-reported)	1.8	2.1	4.2	-1.5	-2.0	-1.7	-1.0	-0.0	-1.9	0.3	-1.9	-1.3
Asthma (self-reported)	0.3	0.6	2.6	0.7	1.6	0.7	0.9	0.3	-0.1	0.6	-0.4	0.4
Osteoporosis (self-reported)	0.3	0.4	2.3	0.4	-0.3	0.1	-0.1	1.5	0.1	-0.6	0.6	0.5
Osteoarthritis (self-reported)	0.9	1.1	3.3	0.5	1.2	0.4	1.1	0.8	-1.8	1.3	0.1	1.2
Medication: Aspirin	0.3	0.3	1.0	0.4	-0.2	0.5	0.4	0.6	0.8	-0.3	-1.0	0.5
Medication: Gliclazide	0.9	1.0	2.4	-0.9	-0.5	-1.1	-0.7	0.1	1.3	-1.6	-1.3	-0.8
Illnesses of father: None of the above (group 1)	0.4	0.5	2.2	-0.0	-1.5	-0.0	-0.0	0.5	-0.6	1.3	0.0	-0.3
Smoking status: Current	0.2	0.4	1.0	-0.5	0.3	-0.5	-0.7	0.6	-1.0	-0.3	-0.4	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.9	0.1	-0.2	-0.3	0.3	1.4	0.0	-0.5	-1.0	-0.0
Whole body water mass	0.6	3.4	11.8	-1.7	-2.4	-1.7	-1.2	-0.5	-3.4	0.1	-1.3	-1.8
Leg predicted mass (right)	0.6	3.4	13.9	-1.5	-2.4	-1.5	-0.9	-0.9	-3.7	-0.2	-1.6	-1.5
Arm fat mass (left)	0.8	3.4	13.0	-1.4	-2.8	-1.6	-1.1	-0.6	-3.6	0.1	-1.3	-1.4
Number of self-reported non-cancer illnesses	0.6	1.0	3.5	0.8	0.6	1.0	1.1	1.9	-0.1	0.9	0.2	1.2
Average weekly champagne plus white wine intake	0.1	0.1	0.8	-0.1	0.9	-0.2	-0.3	-0.1	-0.3	0.3	0.4	0.2
Miserableness	0.4	0.7	4.2	-0.2	0.5	0.2	0.1	-0.3	-2.1	1.1	-0.6	-0.1
Guilty feelings	0.2	0.3	1.8	-0.0	-1.4	0.4	0.4	-0.4	-0.4	0.2	0.7	-0.3
Wears glasses or contact lenses	0.1	0.1	0.4	-0.3	-0.3	-0.7	-0.5	0.1	0.1	-0.2	-0.2	-0.3
Ever taken oral contraceptive pill	1.1	1.2	6.4	0.7	2.5	0.7	1.0	-1.3	-0.5	-0.4	-0.4	0.5
Hearing aid user	0.6	0.7	1.4	0.9	-0.6	0.4	0.8	1.2	0.9	0.4	0.9	1.0
Mother’s age at death	0.4	0.5	2.0	0.6	-0.5	0.5	0.6	0.5	0.5	1.4	0.5	0.8
Financial situation satisfaction	0.4	0.5	1.2	0.9	-0.6	0.5	0.8	-1.1	-0.9	0.1	0.4	0.7
Tinnitus: Yes, now most or all of the time	0.6	0.7	4.2	-0.2	0.1	-0.6	-0.0	0.9	-2.1	0.9	0.1	-0.2
Commuting to job workplace: Public transport	3.3	3.9	8.7	2.4	0.2	2.1	2.2	0.3	0.4	2.7	3.0	2.0
Eye problems/disorders: Glaucoma	0.3	0.3	0.9	0.6	0.3	-0.0	0.3	0.9	-0.9	-0.2	0.5	0.7
Medication: Blood pressure	0.2	0.4	2.4	-0.0	1.5	-0.2	0.4	0.4	0.6	-0.7	0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	3.8	0.5	-0.0	0.4	0.7	2.0	-0.3	-0.6	-0.3	0.4
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.5	-0.1	-0.2	-0.8	-0.2	-1.6	0.3	-0.4	-0.9	-0.5
High cholesterol (Self-reported)	1.1	2.0	4.1	-1.6	-0.6	-1.7	-1.4	-0.5	-0.1	-1.7	-2.0	-1.8
Medication: Bendroflumethiazide	0.3	0.5	1.9	-0.8	0.0	-1.1	-0.1	0.0	-1.4	-0.3	0.3	-0.7
Medication: Paracetamol	4.5	7.0	9.3	3.0	3.0	2.8	2.9	2.7	-1.8	2.3	2.0	2.9
Medication: Lisinopril	0.5	0.6	1.7	0.6	1.2	0.4	0.4	0.2	1.3	0.0	-1.0	0.6
Medication: Atorvastatin	0.5	0.6	2.3	-0.6	-0.3	-0.6	-0.5	1.1	-0.2	-0.9	-1.5	-0.4
Illnesses of father: High blood pressure	0.7	0.9	2.8	-1.2	-0.8	-0.8	-0.9	-0.7	-1.7	0.4	0.0	-1.0
Alcohol drinker status: Never	0.5	0.6	1.0	-0.9	-0.9	-0.8	-0.7	-0.2	-1.0	-0.6	-0.5	-1.0
Ever smoked	0.8	1.5	3.0	1.2	0.7	1.3	1.1	0.7	1.0	1.5	1.7	1.3
Basal metabolic rate	0.7	3.7	14.5	-1.6	-2.6	-1.7	-1.2	-0.5	-3.8	0.2	-1.3	-1.8
Leg fat percentage (left)	0.4	1.3	4.3	-0.8	-2.1	-1.1	-0.6	-0.8	-1.9	-0.2	-0.7	-0.8
Arm fat-free mass (left)	0.5	2.7	9.9	-1.4	-2.4	-1.5	-1.0	-0.3	-3.1	0.5	-0.9	-1.6
Number of operations (self-reported)	0.3	0.5	0.8	0.9	0.9	0.7	0.7	0.7	-0.8	0.3	0.3	0.7
Average weekly beer plus cider intake	0.3	0.4	0.9	-0.8	-1.0	-0.7	-0.8	-0.7	-0.4	-0.5	-0.6	-0.4
Irritability	0.9	1.6	4.8	1.5	2.2	1.2	1.4	0.3	0.3	-0.7	0.4	1.7
Risk taking	1.3	1.8	6.0	-1.3	-2.5	-1.3	-1.2	-1.2	-1.4	0.4	0.3	-1.4
Ever had prostate specific antigen (PSA) test	0.9	1.1	2.7	-1.1	0.2	-1.1	-1.0	0.1	-0.5	-1.3	-1.6	-1.2
Fractured/broken bones in last 5 years	1.0	1.3	3.4	1.0	0.5	0.6	1.0	1.3	-1.1	1.8	1.3	1.1
Age started oral contraceptive pill	0.8	1.0	6.9	0.3	0.0	0.7	0.1	-0.2	2.6	-0.2	1.3	0.4
Diastolic blood pressure, automated reading	0.1	0.3	1.3	-0.4	-1.1	0.4	-0.1	-0.4	-0.7	0.9	-0.0	-0.1
Ever depressed for a whole week	1.1	1.3	7.1	-0.0	-0.8	-0.5	0.1	-1.6	-2.7	0.6	-0.4	-0.9
Unable to work because of sickness or disability	0.7	0.9	2.6	1.2	0.5	1.6	1.3	0.0	0.3	0.4	1.1	0.7
Commuting to job workplace: Cycle	0.8	0.9	4.7	-0.5	-0.2	-0.4	-0.9	-0.7	-2.2	1.3	-0.4	-0.6
Myopia	0.8	1.2	4.2	-0.8	0.3	-1.2	-0.6	1.7	-0.5	-2.0	-0.5	-0.7
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.2	0.8	-1.3	0.2	0.7	-1.1	-1.3	1.5	0.5	0.3
Cholesterol lowering medication	0.5	0.7	2.8	-0.8	0.3	-1.0	-0.5	0.4	0.3	-1.7	-0.8	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.4	-0.6	-1.2	0.1	0.0	-0.5	-1.1	0.5	-1.2	-0.4
Pain experienced in last month	0.5	0.9	2.2	0.5	0.2	0.7	0.1	-1.4	1.4	1.5	0.8	0.4
Supplements: Calcium	0.7	0.8	3.0	0.8	-0.2	0.9	0.6	-0.5	-0.5	1.7	1.1	0.7
Basal cell carcinoma (self-reported)	1.7	2.0	4.0	1.4	1.2	1.4	1.8	1.4	-0.2	0.6	1.8	2.0
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.1	0.9	0.0	1.4	1.1	-0.0	0.5	0.1	0.6	0.7
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	3.0	1.5	0.4	0.9	1.7	0.9	0.4	-0.0	0.7	1.5
Heart disease (siblings)	0.4	0.5	1.4	0.5	0.3	0.6	1.1	-0.2	1.2	-0.6	0.5	0.8
Alcohol drinker status: Previous	0.9	1.1	3.6	-1.0	-0.3	-1.9	-1.1	-0.3	-1.5	-0.2	-0.1	-1.1
Pack years of smoking	0.1	0.2	0.9	-0.2	0.4	-0.0	-0.2	0.5	-1.0	-0.3	-0.0	0.1
Impedance of whole body	0.3	1.6	3.3	1.2	1.8	1.3	0.9	1.2	1.5	0.0	1.4	1.3
Leg fat mass (left)	0.8	3.1	9.2	-1.4	-2.8	-1.7	-1.1	-0.9	-3.0	-0.3	-1.4	-1.5
Arm predicted mass (left)	0.6	3.1	10.3	-1.6	-2.4	-1.7	-1.2	-0.4	-3.2	0.3	-1.1	-1.8