Hub : Genes

VMAC

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Hypothalamus	0.2660	0.0900	5.3e-03	0.021	NA	0.070	NA	0.017	1.0e-01	NA	1.0e-02	NA	1.3e-01
2	GTEx	Esophagus Mucosa	0.0880	0.0370	3.0e-03	0.043	NA	0.043	NA	0.034	6.9e-04	NA	7.3e-04	NA	2.3e-03
3	GTEx	Heart Left Ventricle	0.1742	0.0583	2.3e-03	0.000	NA	-0.005	NA	-0.003	3.0e-01	NA	7.9e-01	NA	4.7e-01
4	GTEx	Skin Not Sun Exposed Suprapubic	0.2220	0.0810	8.7e-03	0.038	NA	0.050	NA	0.048	3.6e-03	NA	1.0e-03	NA	1.3e-03
5	ROSMAP	Brain Pre-frontal Cortex	0.0834	0.0287	5.6e-04	0.027	0.026	0.008	0.036	0.022	1.8e-04	2.3e-04	2.8e-02	1.6e-05	7.4e-04
6	TCGA	Breast Invasive Carcinoma	0.0432	0.0210	1.6e-04	0.015	0.019	0.018	NA	0.021	3.7e-04	6.4e-05	1.0e-04	NA	2.4e-05
7	TCGA	Colon Adenocarcinoma	0.0860	0.0380	1.0e-05	0.068	0.079	0.077	NA	0.059	9.0e-05	2.6e-05	3.3e-05	NA	2.6e-04
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0810	0.0407	8.1e-03	0.004	0.028	0.016	NA	0.000	1.0e-01	3.3e-04	5.6e-03	NA	2.9e-01
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0923	0.0428	2.1e-05	0.023	0.039	0.019	NA	0.028	1.1e-03	3.3e-05	2.9e-03	NA	3.4e-04
10	TCGA	Brain Lower Grade Glioma	0.0712	0.0408	2.6e-04	0.019	0.021	0.016	NA	0.011	3.0e-03	1.6e-03	5.1e-03	NA	1.8e-02
11	TCGA	Prostate Adenocarcinoma	0.0750	0.0444	2.6e-03	0.026	0.020	0.006	NA	0.010	8.2e-04	3.1e-03	6.9e-02	NA	2.5e-02
12	TCGA	Rectum Adenocarcinoma	0.1520	0.0800	4.0e-03	0.035	0.095	0.053	NA	0.047	5.3e-02	3.1e-03	2.2e-02	NA	3.0e-02
13	TCGA	Skin Cutaneous Melanoma	0.1270	0.0770	6.9e-03	0.065	0.081	0.073	NA	0.063	8.1e-03	3.5e-03	5.4e-03	NA	9.2e-03
14	TCGA	Stomach Adenocarcinoma	0.0680	0.0310	1.4e-06	0.070	0.075	0.090	NA	0.084	9.1e-06	4.1e-06	4.4e-07	NA	1.1e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.5	0.8	2.7	1.5	0.9	0.2	-1.6	1.5	0.1	0.7	1.2	0.5	0.2	0.6	0.6	0.0	0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	2.5	0.2	0.9	-0.5	-1.2	1.6	0.2	0.6	1.0	0.4	-0.1	0.6	0.5	0.1	0.3
Depressed Affect (Nagel 2018)	0.4	0.8	3.2	0.8	-0.4	0.2	0.2	-1.8	0.0	-0.6	-1.4	-1.5	-0.0	-1.5	-0.1	-0.5	0.0
Depression (Nagel 2018)	1.3	2.0	5.5	-1.1	0.3	-1.6	0.3	-1.4	-1.7	0.7	-1.2	-2.2	-1.6	-2.4	1.2	-1.3	0.8
Intelligence (Savage-Jansen 2018)	0.4	1.3	2.9	-0.4	-1.2	1.7	0.4	0.8	1.1	-1.0	0.7	1.5	-0.0	1.4	-1.4	1.3	-1.5
Neuroticism (Nagel 2018)	0.3	0.6	2.1	-0.2	0.2	-0.3	0.0	-1.4	-0.7	0.3	-1.0	-1.2	-0.8	-1.3	0.4	-0.7	0.7
Schizophrenia (2018)	0.1	0.2	1.0	-1.0	0.4	-0.8	-0.3	0.9	0.1	0.3	0.6	0.1	-0.1	0.2	0.2	0.1	0.1
Schizophrenia vs Biploar Disorder	0.9	1.2	3.3	-1.5	0.0	0.9	0.8	0.4	1.6	-1.0	0.5	0.9	1.8	1.2	-1.2	1.4	-0.5
Worry (Nagel 2018)	0.2	0.5	1.7	-1.3	0.5	-0.7	0.1	-0.2	-0.5	1.0	0.0	-0.4	-1.1	-0.2	0.7	-0.6	1.1
Alzheimer’s Disease (in mother)	0.3	0.4	1.7	1.3	0.6	1.0	0.1	-0.3	0.3	0.5	-0.1	-0.1	0.7	0.6	0.5	-0.6	0.6
Alzheimer’s Disease (in father)	0.4	0.4	1.7	1.3	0.3	0.8	-1.0	-0.3	0.1	-0.7	-0.5	0.3	1.1	0.3	-0.1	0.2	-0.3
Alzheimer’s Disease (including proxy)	0.4	0.6	3.5	1.9	0.1	1.4	0.0	-0.2	0.6	-0.5	-0.3	0.5	1.2	0.9	-0.1	-0.1	-0.4
Crohns Disease (2017)	1.0	2.2	6.5	-1.1	1.5	-1.8	2.5	0.8	-0.6	2.2	0.9	-0.3	-1.2	-0.3	1.9	-1.2	2.0
Irritable Bowel Disease (IBD)	0.8	1.9	4.8	-0.5	0.8	-1.6	2.1	0.6	-1.0	2.2	0.7	-0.6	-1.9	-0.4	1.9	-1.4	1.6
Ulcerative Colitis (UC)	0.5	0.9	2.6	0.5	-0.1	-0.9	1.4	0.3	-0.8	1.3	0.1	-0.8	-1.6	-0.4	1.2	-1.2	0.6
Major Depression (MDD)	2.9	3.5	8.7	0.7	0.0	-3.0	-0.4	-1.1	0.0	2.6	0.1	-1.2	-1.2	-2.3	2.9	-2.6	2.8
Reaction Time	2.1	4.0	7.7	1.0	1.6	-1.6	-1.3	-2.1	-1.4	1.6	-2.3	-2.8	-1.7	-2.3	2.3	-2.7	2.1
Verbal and Numeric Reasoning (VNR)	1.6	3.9	7.9	-0.4	-1.7	1.8	1.4	1.2	1.8	-2.1	1.6	2.8	1.0	2.1	-2.5	2.7	-2.8
Breast Cancer	0.6	1.5	3.7	1.5	-1.7	1.2	-1.9	-1.3	0.5	-1.6	-0.1	0.3	0.5	0.4	-1.6	0.9	-1.6
Ovarian Cancer	0.2	0.3	2.5	1.6	-0.3	0.0	-0.3	-0.4	0.2	0.3	0.2	-0.7	-0.4	0.2	0.1	0.1	-0.3
Prostate Cancer	0.4	0.5	1.8	0.8	0.1	0.6	-1.2	-1.3	-0.1	-0.5	-1.4	-0.8	0.4	-0.5	-0.0	-0.3	0.2
Age at First Birth	0.3	0.5	2.8	-1.7	0.8	0.1	0.5	1.1	-0.7	0.6	0.6	-0.2	-0.2	-0.2	0.5	-0.2	0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.5	0.8	2.7	0.8	-1.0	-0.7	-0.5	-1.3	0.0	-0.4	-1.6	-1.0	-1.1	-0.9	-0.0	-0.6	-0.4
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	1.0	1.6	5.8	-0.5	1.8	-1.0	1.0	0.9	-0.3	2.4	1.3	0.5	-0.6	0.1	2.0	-1.2	1.8
Mean Putamen Volume	0.3	0.4	1.2	1.1	-0.9	0.8	-0.2	-0.2	0.4	-0.8	-0.1	0.2	-0.3	0.3	-0.9	0.5	-0.8
Fasting Glucose	1.4	1.7	9.4	0.6	-0.8	0.9	-0.0	-3.1	0.8	-1.4	-1.1	0.1	2.6	-0.9	-0.8	0.5	-0.4
HbA1C	0.7	0.8	2.0	1.2	-0.4	0.5	-0.3	-0.9	0.8	-1.2	0.1	0.6	1.4	0.3	-1.1	1.3	-1.0
HDL Cholesterol	0.4	0.6	2.2	0.0	-0.5	-0.4	-0.5	-0.1	0.0	0.3	-1.1	-1.5	-1.0	-1.3	0.5	-1.3	0.1
LDL Cholesterol	0.2	0.3	1.3	1.0	-1.1	-0.0	0.2	-0.4	0.0	-0.5	0.1	0.5	0.2	0.2	-0.6	0.3	-0.5
Lupus	0.5	0.8	2.2	0.8	-1.1	0.0	-0.6	-1.0	-0.8	-1.3	-1.5	-0.4	-0.6	-0.8	-0.8	0.1	-1.4
Neuroticism (2016)	1.9	2.7	6.6	-0.1	1.5	-2.0	0.3	1.2	-1.4	2.6	0.0	-1.0	-2.4	-1.2	2.1	-1.7	2.4
Primary Biliary Cirrhosis	1.3	1.8	6.0	-0.0	1.6	-1.7	1.4	-0.0	-0.5	2.1	1.1	0.1	0.2	-0.7	1.9	-1.1	2.5
Rheumatoid Arthritis	0.9	1.3	3.8	-2.0	1.4	-1.6	-0.5	-0.5	-1.2	1.1	0.2	-0.4	-0.6	-1.2	1.1	-0.8	1.4
Schizophrenia (2014)	0.7	1.5	4.5	-0.2	0.4	0.2	-1.3	1.5	1.2	-0.1	2.1	1.6	2.1	1.4	-0.3	1.3	-0.3
Triglycerides	0.6	1.0	5.6	0.6	-0.7	0.1	-0.7	-2.4	0.0	-1.4	-0.9	-0.1	1.5	-0.2	-1.0	0.9	-0.8
Type 2 Diabetes (T2D) (2012)	1.0	1.2	6.0	-2.5	0.0	0.2	1.2	1.8	0.0	0.8	1.5	1.1	0.1	0.9	0.4	0.2	0.6
Ulcerative Colitis	0.6	0.9	3.0	0.2	0.0	-0.3	1.7	1.7	0.0	1.2	1.2	0.7	-1.1	1.1	0.5	-0.0	0.4
Blood Eosinophil Count	2.1	16.2	31.2	2.1	3.5	-5.5	1.2	-0.3	-5.6	4.8	-1.3	-3.6	-4.2	-4.0	5.2	-4.9	5.0
Blood Platelet Count	0.2	2.1	8.0	2.8	-0.1	-0.9	0.9	-1.1	-1.9	0.7	-0.9	-1.2	-2.3	-1.3	1.3	-1.8	0.6
Blood Red Count	0.2	1.6	5.5	2.1	0.9	-0.9	-2.2	-0.7	-0.2	0.3	-2.3	-1.3	-1.0	-0.6	0.7	-1.0	0.6
Blood White Count	0.1	0.5	3.0	-0.6	-1.2	-0.1	1.7	0.8	0.1	-0.4	1.0	0.4	0.1	0.2	-0.4	0.4	-0.2
Heel T-Score	0.5	3.6	16.7	3.1	0.2	2.4	-0.8	-2.5	2.2	-1.8	-1.4	0.7	4.1	0.0	-0.7	0.8	-0.2
BMI	0.4	2.3	4.9	1.0	1.6	-1.4	0.5	-1.0	-1.7	0.7	-2.0	-1.8	-1.1	-2.2	1.6	-2.1	1.2
Height	0.3	6.3	19.3	0.9	1.4	-2.3	-0.1	4.1	-1.9	4.1	4.4	2.3	-2.7	1.6	2.0	-1.1	2.0
Waist Hip Ratio (WHR)	0.1	0.6	3.1	1.8	0.8	-0.1	0.9	-1.1	-0.2	0.3	-1.1	-0.9	-0.3	-0.6	0.5	-0.1	0.3
Systolic Blood Pressure	0.2	1.1	4.3	-2.1	-1.2	0.2	0.5	1.8	-0.3	-0.3	1.3	1.3	-0.1	0.9	-0.6	0.5	-1.1
Smoking Status	0.6	1.4	5.0	1.6	-0.8	1.8	-0.0	-1.7	0.3	-1.4	-2.2	-1.3	0.7	-0.7	-0.6	-0.0	-0.6
Allergy or Eczema	1.8	4.8	10.1	-1.7	2.7	-2.3	0.7	2.2	-2.7	3.2	1.5	-0.6	-2.1	-1.0	2.9	-2.4	2.4
Cardiovascular Disease	0.5	1.6	3.2	0.7	-1.5	1.7	-0.8	0.7	0.9	-1.1	1.1	1.8	0.6	1.4	-1.4	1.4	-1.8
Hypothyroidism (self reported)	0.1	0.2	1.3	0.3	-0.0	-0.3	1.1	-0.2	0.0	0.4	-0.4	-0.4	-0.8	0.7	0.2	0.2	0.1
Respiratory disease	0.9	2.1	4.3	0.9	1.9	-0.9	1.5	0.4	-1.4	1.7	-0.8	-1.5	-1.4	-1.5	2.0	-2.1	1.3
Type 2 Diabetes (T2D) (2018)	1.0	1.9	8.6	-0.2	1.1	-0.5	2.1	1.9	0.7	1.2	2.9	1.4	0.8	1.7	0.6	0.6	0.8
Lung FEV1/FVC ratio	0.7	3.3	13.1	-0.7	-3.6	1.0	-0.0	-1.9	0.5	-2.2	-2.8	-2.1	-0.9	-2.2	-1.3	-0.4	-1.7
Lung FVC	5.5	28.1	57.5	0.3	5.4	-6.2	1.7	-0.7	-6.0	7.6	-1.1	-5.1	-5.5	-4.1	7.5	-6.9	7.2
Neuroticism	0.5	1.2	3.8	-0.9	1.5	-0.7	0.1	-1.3	-0.7	1.3	-0.6	-1.3	-0.7	-0.9	1.3	-0.9	1.9
Chronotype (morning person)	0.9	2.1	5.2	-0.9	-1.5	1.6	-2.3	-1.1	1.5	-2.2	-0.9	0.2	1.6	0.4	-1.6	1.3	-1.7
Hair Pigment	0.1	2.0	9.5	-1.6	0.8	0.2	2.2	3.1	1.1	0.8	2.1	0.8	0.8	1.6	0.3	0.7	0.7
Tanning	0.3	3.5	6.3	1.1	1.6	-2.3	0.4	-1.6	-2.2	1.6	-1.2	-2.3	-1.6	-2.5	2.1	-2.5	2.1
Hand grip strength (left)	0.8	2.1	12.7	0.2	-0.7	-0.5	1.8	3.6	-0.1	0.6	1.8	2.4	-0.7	1.6	-0.3	0.5	-0.8
Number of treatments/medications taken	0.3	0.6	1.3	-0.3	1.0	-1.1	-0.1	-0.7	-0.8	1.2	0.8	-0.3	-0.9	-0.1	1.1	-0.8	0.4
Average weekly spirits intake	0.2	0.3	0.6	0.2	0.4	-0.3	-0.8	-0.0	-0.7	0.5	0.7	0.4	0.1	-0.4	0.7	-0.6	0.7
Sensitivity / hurt feelings	0.9	1.5	3.6	0.9	0.7	-1.1	0.7	-0.9	-1.4	0.9	-1.4	-1.9	-1.3	-1.8	1.1	-1.2	1.0
Frequency of depressed mood in last 2 weeks	1.6	2.2	5.2	-1.2	0.9	-2.1	0.6	-0.4	-1.5	1.1	-1.1	-2.2	-1.5	-2.3	1.5	-1.6	1.4
Hearing difficulty/problems: Yes	1.7	2.6	5.9	1.2	1.9	-2.3	0.2	-1.0	-1.1	1.9	-0.6	-1.7	-1.1	-1.7	2.0	-1.8	2.4
Relative age of first facial hair	1.0	2.1	4.0	1.6	-0.9	2.0	0.5	1.7	0.9	-1.2	2.0	1.5	1.3	1.2	-1.6	1.8	-1.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.0	0.9	0.5	-1.0	-0.9	-0.5	-0.8	0.6	0.4	-0.3	-0.5	-0.1	0.6	-0.3	0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	3.8	-1.9	0.2	-0.5	-0.4	0.1	0.8	0.4	1.5	0.4	0.4	0.3	0.1	0.1	0.1
Ever had hysterectomy (womb removed)	0.5	0.6	4.4	-2.1	0.2	0.5	0.3	0.1	0.9	-0.6	-0.2	0.3	1.5	-0.0	-0.4	-0.1	-0.4
Systolic blood pressure, automated reading	1.6	4.5	9.5	-1.8	2.6	-2.8	-0.6	0.5	-3.1	2.7	0.6	-1.3	-1.2	-1.5	3.0	-2.8	2.3
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.2	-0.4	0.5	-1.2	1.2	0.4	-1.2	1.3	-0.0	-1.1	-1.5	-1.4	1.2	-1.5	0.9
Angina	0.5	0.7	3.3	0.4	-0.1	0.9	0.3	-0.1	1.8	-0.8	0.3	0.9	1.0	0.8	-0.7	1.1	-0.7
Medication for hormone replacement therapy	0.4	0.4	4.2	-2.0	-0.3	-0.2	-0.6	-0.3	0.6	-0.1	0.5	-0.2	0.4	-0.4	-0.3	0.2	-0.1
Vitamin and mineral supplements	0.6	0.8	3.0	0.6	0.4	-0.6	-1.7	-1.2	-0.8	-0.1	-0.9	-1.1	0.2	-1.6	0.7	-0.7	0.4
Supplements: Zinc	0.4	0.5	2.5	-0.4	-1.1	0.1	0.0	1.6	0.7	0.2	0.8	0.9	-0.4	0.6	-0.2	0.3	-0.5
Medication: Co-codamol	0.6	0.6	2.4	0.4	-0.1	0.4	0.8	-0.4	0.8	-0.6	0.8	1.0	0.5	0.8	-0.7	1.2	-1.6
Medication: Metformin	0.5	0.6	2.0	0.3	0.5	0.4	1.4	0.9	0.8	-0.0	0.9	1.2	1.1	1.2	-0.1	0.2	-0.1
Diabetes (father)	0.3	0.4	1.5	-0.5	-0.2	0.4	0.8	0.3	0.3	-0.3	0.8	0.9	-0.2	0.9	-0.8	1.2	-0.3
Diabetes (mother)	0.4	0.6	3.6	0.6	1.1	-0.0	0.4	-0.8	0.2	0.0	-1.9	-0.5	0.7	0.2	0.4	-0.6	0.7
Severe depression (siblings)	0.6	0.7	3.0	1.1	0.6	-0.9	-1.7	0.7	-0.5	0.9	0.9	0.3	-0.1	-0.1	0.9	-0.6	0.9
Pack years adult smoking proportion	0.6	0.9	3.2	-0.1	-1.8	0.4	0.1	-1.1	0.4	-1.0	-1.8	-1.0	-0.3	-1.0	-0.8	0.0	-1.1
Impedance of leg (right)	0.6	2.8	5.6	-1.8	-1.1	1.3	0.2	1.5	1.9	-0.9	2.3	2.3	1.2	2.4	-1.5	2.0	-1.6
Leg fat-free mass (left)	0.3	1.5	13.4	3.7	0.4	-1.1	0.1	0.0	-1.1	0.7	-0.8	-0.3	-1.0	-0.5	0.8	-1.3	0.7
Trunk fat percentage	1.2	4.8	10.9	1.9	3.3	-2.7	-0.4	-0.2	-2.6	2.5	-1.2	-1.9	-2.2	-1.2	2.9	-2.6	2.4
Hand grip strength (right)	1.0	2.8	16.6	0.7	-0.7	0.1	1.5	4.1	0.7	0.8	2.2	2.8	-0.6	2.0	-0.2	0.5	-0.6
Townsend deprivation index at recruitment	1.3	1.9	6.5	1.6	-1.3	1.1	-1.3	-1.1	1.7	-1.8	-2.5	0.1	0.6	0.8	-1.1	0.7	-1.7
Current tobacco smoking	0.5	0.8	2.7	0.7	-1.6	1.2	-0.3	-0.2	0.9	-0.9	-1.2	-0.3	-0.6	0.4	-0.6	0.0	-1.6
Average weekly fortified wine intake	1.0	1.2	4.6	-2.1	0.1	1.0	1.8	1.3	0.8	0.6	1.5	0.9	-0.2	1.2	0.1	0.0	-0.3
Maternal smoking around birth	0.3	0.4	2.1	-1.0	1.4	-0.4	0.5	0.6	-0.5	0.0	0.2	-0.2	0.8	-0.4	0.3	-0.2	0.6
Fed-up feelings	0.3	0.6	2.7	1.6	-1.2	0.8	-0.8	-0.1	0.5	-0.8	-0.7	-0.4	-0.4	-0.5	-0.5	0.2	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	4.2	-1.3	-0.3	-0.8	-0.7	-0.9	-1.2	0.3	-2.0	-2.0	-2.0	-2.0	0.9	-1.4	0.2
Relative age voice broke	0.2	0.3	1.0	0.6	-0.8	1.0	0.5	1.0	0.2	-0.5	0.2	-0.2	0.3	-0.2	-0.4	-0.2	-0.6
Taking other prescription medications	0.4	0.6	2.0	0.3	1.4	-1.4	0.2	-0.8	-0.3	0.8	0.0	-0.5	0.3	-0.2	0.9	-0.7	0.9
Age when periods started (menarche)	0.1	0.3	1.4	0.6	-0.6	0.6	-1.2	1.0	-0.2	-0.4	-0.1	-0.0	0.3	-0.3	-0.4	-0.3	-0.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.0	-0.8	-0.4	0.3	0.3	-1.4	-0.1	-1.2	-1.4	-0.8	1.1	-1.1	-0.6	-0.4	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.5	0.1	1.4	-1.5	-0.8	-0.9	-1.0	1.0	0.5	-0.5	0.8	-1.9	1.2	-0.6	1.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.9	1.4	-0.4	0.3	-0.4	0.3	0.7	0.1	0.1	-0.2	0.1	-0.1	0.1	-0.2	0.3
Qualifications: CSEs or equivalent	0.5	0.6	2.3	0.5	-0.7	0.1	-1.5	0.1	1.1	-0.9	0.5	0.5	0.4	0.6	-1.1	1.2	-0.6
Serious illness, injury or assault to yourself	0.3	0.4	1.0	0.9	1.0	-0.4	0.3	-0.0	0.9	0.5	-0.6	-0.6	0.2	-0.3	0.6	-0.2	0.8
High blood pressure	0.3	0.7	3.8	0.7	-0.3	-0.3	0.2	1.5	-0.5	0.8	2.0	1.1	-0.7	0.6	0.1	0.2	-0.1
Hayfever, allergic rhinitis or eczema	1.1	2.3	4.6	-1.1	1.9	-1.8	0.2	1.9	-1.8	2.1	1.6	-0.4	-1.4	-0.8	1.8	-1.4	1.4
Multivitamins +/- minerals	2.1	2.7	9.0	0.4	-0.0	0.8	1.2	1.8	1.6	-0.1	2.7	2.7	1.0	3.0	-1.2	1.8	-0.5
Stomach or abdominal pain in last month	0.3	0.3	1.6	0.0	-0.7	-0.0	-1.3	0.2	0.9	-0.5	0.2	0.2	0.7	0.6	-0.4	0.5	-0.3
Supplements: Glucosamine	1.3	1.7	7.3	-1.0	0.9	-1.7	1.6	1.2	-0.9	1.6	2.7	0.7	-1.5	0.2	1.0	-0.6	0.7
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	6.1	1.3	-0.3	0.2	-0.4	1.2	2.2	-0.8	1.8	2.4	0.9	1.7	-1.3	2.5	-1.1
Medication: Atenolol	2.5	3.1	6.5	-0.3	-1.5	1.8	0.1	-0.1	2.2	-2.5	0.9	2.0	2.2	0.9	-2.4	2.2	-2.2
Medication: Levothyroxine sodium	0.3	0.5	2.9	0.3	0.3	-0.7	1.7	-0.3	-0.3	0.5	-1.1	-0.6	-1.0	-0.2	0.6	-0.5	0.1
Sitting height	0.3	2.4	8.2	1.5	0.6	-1.1	-2.3	1.9	-0.8	2.1	2.9	1.5	-0.3	0.6	1.1	-0.8	1.9
Chronic bronchitis/emphysema (father)	0.3	0.4	2.9	1.7	0.4	-0.7	-0.9	0.2	-0.2	0.4	0.3	0.2	-0.4	-0.4	0.5	-0.3	0.1
High blood pressure (mother)	0.3	0.5	1.4	0.6	-1.2	0.2	0.2	-1.0	-0.0	-0.8	0.5	0.2	-0.7	-0.1	-0.8	0.9	-1.0
Body mass index (BMI)	0.4	1.8	4.6	2.1	1.7	-1.4	0.2	-0.6	-1.4	1.1	-1.3	-1.1	-1.0	-1.3	1.7	-1.7	1.1
Impedance of leg (left)	0.5	2.4	8.1	-2.8	-0.8	0.9	-0.5	1.6	1.4	-0.6	2.2	1.9	0.8	2.0	-1.2	1.7	-1.2
Leg predicted mass (left)	0.3	1.6	13.8	3.7	0.4	-1.2	0.1	-0.0	-1.2	0.7	-0.8	-0.3	-1.0	-0.6	0.8	-1.4	0.7
Trunk fat mass	0.9	4.0	8.5	2.5	2.9	-2.5	-0.6	-0.1	-2.4	2.3	-0.8	-1.3	-1.9	-0.9	2.6	-2.4	2.2
Waist circumference	0.6	2.2	6.9	2.6	1.9	-1.8	0.0	-0.4	-1.6	1.5	-0.8	-1.1	-1.1	-1.1	1.9	-1.7	1.3
Number of incorrect matches in round	0.5	0.9	2.9	-1.1	-0.9	1.7	-1.2	0.8	0.8	-0.5	0.5	0.7	0.4	1.1	-0.8	0.6	-1.2
Past tobacco smoking	0.6	1.0	4.5	-1.7	-2.1	0.1	-0.4	-0.2	0.6	-1.1	-0.0	0.6	-0.1	0.5	-1.3	0.6	-1.6
Alcohol usually taken with meals	0.8	1.2	4.9	-0.0	-0.2	0.4	-1.7	1.2	0.4	-0.0	2.2	2.0	-0.0	1.4	-0.7	1.1	-0.3
Nervous feelings	1.6	2.9	6.2	-1.5	0.5	-1.7	0.9	-1.8	-2.1	1.2	-1.1	-2.4	-1.7	-2.5	1.5	-2.0	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.8	-0.1	-0.1	-0.5	1.4	-1.0	-0.4	0.3	-0.9	-1.2	-0.5	-0.6	0.2	-0.4	0.8
Hearing difficulty/problems with background noise	0.7	1.2	2.9	0.0	1.7	-1.3	-0.7	-0.2	-0.4	1.3	-0.7	-0.9	-1.5	-0.7	1.4	-1.3	1.2
Hair/balding pattern: Pattern 2	0.8	1.0	3.3	-0.9	1.8	-0.5	1.8	-0.4	-1.0	0.8	-0.5	-0.7	0.2	-0.2	1.0	-0.8	1.5
Had menopause	0.1	0.1	1.4	0.0	-0.0	-0.1	-0.4	-0.4	0.1	0.4	1.2	0.1	-0.1	0.0	0.3	-0.3	-0.1
Had other major operations	0.2	0.3	2.3	0.4	-0.2	-0.8	1.5	-0.3	0.3	-0.0	0.1	0.1	-0.7	-0.2	-0.1	0.5	-0.3
Forced vital capacity (FVC)	2.5	9.7	19.4	1.0	2.3	-3.6	0.2	-0.4	-4.0	4.3	-0.5	-2.8	-3.2	-2.8	4.1	-4.4	4.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.5	0.1	-0.3	0.3	-0.8	-0.5	0.3	-0.4	0.7	0.4	1.6	-0.9	-0.2	0.3	0.0
Ever unenthusiastic/disinterested for a whole week	3.3	4.1	9.1	2.1	2.4	-1.9	0.6	0.1	-1.4	2.8	-0.5	-2.0	-2.1	-1.6	3.0	-2.5	2.6
Qualifications: None of the above	0.5	1.0	3.0	1.4	0.6	0.4	-1.1	-1.7	0.5	-0.7	-1.5	-1.6	0.9	-0.4	-0.3	0.5	-0.3
Financial difficulties in last 2 years	0.6	0.8	3.5	1.9	0.6	-0.6	-0.1	-1.3	0.2	0.5	-1.2	-0.6	0.4	-0.7	1.0	-0.9	0.8
Mouth/teeth dental problems	0.3	0.5	1.7	-1.0	0.2	-1.0	0.1	0.1	-0.7	0.8	0.1	-0.4	-1.3	-0.6	0.6	-1.0	0.7
Heart attack	0.9	1.1	3.6	-0.4	-1.2	1.3	0.2	-1.2	1.9	-1.5	-0.2	0.3	1.2	0.4	-1.4	1.1	-0.9
Allergy	0.4	0.8	1.5	0.4	-1.1	0.7	0.0	-1.1	1.0	-1.2	-0.5	0.8	0.7	1.0	-1.2	1.2	-0.8
Pain all over the body in last month	0.6	0.6	3.2	1.6	0.2	-0.3	-1.8	0.1	-0.5	0.6	-0.2	-0.4	-1.0	-0.1	0.4	-0.5	0.4
Diabetes (self-reported)	1.2	1.9	7.2	1.4	0.9	-0.2	2.7	1.5	1.2	0.4	2.3	1.7	1.0	1.8	0.1	0.7	-0.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.5	0.9	1.9	-1.5	-0.3	-0.7	-0.5	1.5	0.6	-1.0	0.1	-0.2	1.3	-0.5	1.9
Medication: Ramipril	0.3	0.4	2.5	-0.1	0.4	0.6	-0.2	-0.3	0.3	-0.4	1.1	0.6	1.6	0.2	-0.4	0.4	-0.2
Medication: Simvastatin	0.4	0.6	3.1	0.0	-0.6	0.9	0.4	0.9	0.7	0.0	1.8	0.6	-0.1	1.1	-0.4	0.8	-0.4
Fluid intelligence score	1.3	2.6	8.7	-1.4	-1.3	1.4	1.4	1.6	1.4	-0.6	2.1	3.0	0.1	2.1	-1.3	1.8	-1.5
Illnesses of siblings	0.7	0.9	4.8	0.4	-0.9	1.0	0.1	-1.4	0.2	-1.3	-2.2	-1.2	-0.2	-0.5	-0.8	-0.0	-0.6
Neuroticism score	0.8	1.7	3.5	-0.2	1.0	-1.0	0.4	-0.7	-0.9	1.5	-1.2	-1.8	-1.6	-1.5	1.6	-1.7	1.9
Weight	0.4	2.1	9.7	3.1	1.4	-1.7	-0.3	0.2	-1.6	1.6	-0.2	-0.3	-1.3	-0.6	1.6	-1.8	1.2
Impedance of arm (right)	0.2	1.0	2.0	-1.2	1.4	-1.4	1.4	1.0	-0.7	1.2	0.6	-0.2	-1.2	0.2	0.9	-0.5	0.9
Arm fat percentage (right)	0.9	3.6	9.9	1.9	3.1	-2.4	0.8	-0.3	-2.1	1.9	-1.3	-1.4	-1.5	-1.3	2.5	-2.2	1.9
Trunk fat-free mass	0.2	0.9	9.4	3.1	-0.6	-0.4	-0.2	0.1	-0.6	0.4	0.8	0.7	-0.3	0.1	0.2	-0.6	-0.0
Hip circumference	0.3	1.3	3.1	1.5	1.8	-1.6	-0.5	0.4	-1.1	1.4	-0.2	-0.4	-0.6	-0.4	1.6	-1.5	1.3
Time employed in main current job	0.4	0.5	1.5	0.7	-0.4	-0.2	1.0	0.2	-0.1	-0.3	1.2	1.1	-0.1	0.5	-0.5	0.7	-0.9
Alcohol intake versus 10 years previously	1.7	2.6	5.0	0.9	1.9	-1.5	-0.5	-0.9	-1.3	1.5	-1.6	-2.0	-1.2	-2.0	1.9	-1.9	2.2
Father’s age at death	2.0	2.7	6.3	0.3	0.9	-1.7	-0.4	-1.6	-1.4	1.0	-2.4	-2.5	-1.6	-2.0	1.4	-2.1	1.6
Worrier / anxious feelings	0.2	0.4	1.1	0.1	0.2	-0.5	-0.2	-0.1	-0.2	0.7	-0.3	-0.6	-0.7	-1.0	0.8	-0.9	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	2.9	1.7	0.3	-0.4	-0.1	-1.3	-0.2	0.6	-0.9	-1.6	-0.5	-0.9	0.9	-0.9	1.0
Falls in the last year	0.9	1.2	5.5	0.9	1.6	-0.7	-2.3	-0.7	-0.4	1.4	0.3	-0.8	-0.1	0.1	1.2	-0.7	1.7
Hair/balding pattern: Pattern 3	1.4	2.1	5.0	1.0	1.7	-2.2	-0.4	-1.0	-1.3	2.0	-0.4	-1.0	-1.5	-1.0	2.2	-1.6	1.5
Number of live births	0.2	0.3	1.4	-0.1	-0.1	-0.0	-1.2	-0.5	0.2	-0.1	0.5	0.1	1.1	-0.1	-0.0	0.0	0.6
Forced expiratory volume in 1-second (FEV1)	2.5	8.5	18.9	0.4	1.6	-3.4	-0.0	-0.6	-3.9	3.7	-1.0	-3.0	-3.1	-3.2	3.7	-4.3	3.7
Pulse rate	0.2	0.4	1.1	0.8	-0.3	0.7	-0.9	-0.5	0.6	-0.6	-1.1	-0.9	0.2	0.2	-0.5	0.3	-0.3
Happiness	1.3	1.5	5.7	-0.1	0.8	-0.1	-2.4	-0.9	-1.4	0.9	-1.4	-1.3	-1.4	-1.1	1.1	-1.6	1.1
Noisy workplace	1.3	1.7	8.6	0.2	-0.8	1.1	-0.3	-2.9	-0.2	-1.1	-2.3	-2.1	-0.0	-0.9	-0.2	-0.6	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	1.0	6.1	0.2	-0.4	-0.4	2.5	2.0	-0.4	0.1	1.1	0.8	-0.6	0.2	-0.6	0.4	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.4	1.3	-1.6	0.8	-0.2	0.6	0.2	-0.2	0.8	1.3	0.1	0.6	-0.6	0.6	-0.8
Mouth/teeth dental problems: Dentures	0.4	0.8	3.6	1.9	0.5	0.2	-0.8	-0.7	1.0	-0.7	-0.4	0.3	1.8	0.2	-0.4	0.5	-0.3
Asthma	0.9	1.8	4.0	1.7	1.9	-1.1	-0.3	0.0	-1.3	1.5	-0.9	-1.3	-1.1	-1.3	2.0	-1.7	1.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	2.7	0.9	-1.3	1.6	-1.1	-0.1	1.6	-1.2	-0.1	1.3	1.1	1.3	-1.4	1.3	-1.3
Medication: Cholesterol lowering	1.0	1.6	6.4	1.0	-1.0	1.0	0.5	1.4	1.2	-0.1	2.5	1.9	0.1	1.7	-0.7	1.2	-0.8
Depression (self-reported)	1.6	2.0	4.1	0.4	1.2	-1.5	-1.8	-0.5	-1.4	2.0	-0.0	-1.1	-1.3	-0.8	2.0	-1.5	2.0
Medication: Lansoprazole	0.7	0.8	2.2	1.5	0.7	-0.2	-0.8	-1.0	0.9	-0.0	-1.4	-1.2	1.0	-0.6	0.3	-0.2	0.6
Prospective memory result	0.6	0.7	3.1	0.1	1.3	-0.3	-1.8	0.4	-0.6	0.6	-1.0	-1.0	-1.0	0.2	0.9	-0.6	0.5
Lung cancer (father)	1.1	1.3	2.9	0.5	-1.0	1.4	-0.9	0.3	1.7	-1.1	0.6	1.0	1.2	1.4	-1.3	1.3	-1.6
Illnesses of mother	1.4	1.7	4.4	-0.8	-2.1	1.4	-1.4	1.2	1.4	-1.7	-0.1	1.2	0.7	0.2	-1.7	0.9	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.8	14.6	0.2	1.6	-3.3	0.1	0.2	-3.5	3.6	-0.2	-2.2	-2.8	-2.4	3.3	-3.8	3.6
Pulse wave Arterial Stiffness index	0.6	0.7	1.6	0.7	-0.5	0.7	-1.0	0.8	0.6	-1.1	0.0	1.0	1.0	0.5	-1.3	1.0	-0.8
Impedance of arm (left)	0.3	1.2	2.4	-1.3	1.5	-1.5	0.9	0.5	-1.0	1.5	0.3	-0.8	-1.3	-0.3	1.2	-0.7	1.3
Arm fat mass (right)	0.5	2.3	5.9	2.4	2.3	-1.7	0.1	0.0	-1.7	1.6	-0.7	-0.8	-1.2	-0.7	1.9	-1.8	1.5
Trunk predicted mass	0.1	0.9	9.2	3.0	-0.6	-0.4	-0.1	0.1	-0.7	0.4	0.7	0.7	-0.4	0.1	0.1	-0.6	-0.0
Standing height	0.2	2.1	7.5	2.7	-0.6	-0.8	-1.2	1.9	-0.7	1.3	2.6	1.8	-1.1	1.3	0.1	-0.3	0.3
Length of working week for main job	1.1	1.2	4.8	2.2	-1.2	0.1	1.8	1.2	-0.1	-0.1	0.7	1.4	-0.7	0.6	-0.5	0.6	-1.2
Exposure to tobacco smoke at home	0.6	0.6	4.7	0.7	0.3	-0.8	2.2	1.2	-0.9	0.3	0.1	0.4	-0.3	0.7	0.0	0.4	0.1
Breastfed as a baby	0.7	0.8	3.8	0.0	-0.9	0.4	1.5	1.6	0.0	0.3	2.0	0.7	-0.6	0.8	-0.5	0.5	-0.1
Tense / ‘highly strung’	0.6	0.9	3.4	-0.5	0.8	-0.9	1.8	-0.1	-0.4	1.1	-0.5	-1.2	-1.0	-0.6	0.9	-0.7	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.0	0.7	0.3	-0.7	-0.1	-0.6	-0.5	0.6	-0.8	-1.0	-0.8	-0.7	0.8	-0.9	0.6
Hair/balding pattern: Pattern 4	2.5	6.0	13.4	-0.1	3.2	-3.1	0.1	0.6	-2.5	3.7	0.5	-1.9	-2.7	-1.6	3.5	-2.9	3.0
Birth weight of first child	0.2	0.4	2.2	-0.5	0.6	0.4	0.9	1.5	0.5	0.4	0.7	0.5	0.4	0.7	0.1	0.1	0.7
Peak expiratory flow (PEF)	0.7	1.7	3.5	-0.4	0.7	-1.8	0.5	-0.3	-1.9	1.6	0.6	-1.1	-1.0	-1.4	1.4	-1.8	1.8
Pulse wave reflection index	0.6	0.7	2.5	-1.4	1.0	0.2	0.9	1.6	0.0	0.9	0.4	0.9	0.7	0.4	0.6	-0.4	0.9
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.9	-0.5	-0.2	1.0	-0.0	-1.4	1.4	-0.8	-1.3	-0.9	1.0	0.6	-0.7	0.5	0.0
Loud music exposure frequency	0.6	0.7	4.3	0.3	-1.0	0.9	-0.4	-0.5	1.2	-0.7	-2.1	-0.6	-0.5	0.2	-0.2	-0.2	-0.6
Qualifications: O levels/GCSEs or equivalent	3.4	5.5	10.8	-0.1	-2.9	2.3	1.1	2.0	2.0	-2.3	2.3	3.0	1.0	2.4	-3.0	2.6	-3.3
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.4	0.6	-1.3	1.5	0.5	-0.2	0.4	-1.4	-0.1	0.3	1.2	0.8	-1.3	1.4	-1.1
Blood clot in the leg (DVT)	2.3	3.0	7.7	1.3	-1.7	2.1	-0.3	-0.9	2.2	-2.5	-0.0	1.0	2.8	1.1	-2.2	1.9	-1.6
Medication: Paracetamol	0.4	0.7	3.5	1.3	0.6	-0.7	-1.9	0.0	-0.4	1.0	0.0	-0.5	-0.8	0.1	1.0	-0.7	0.5
Headache pain in last month	0.2	0.3	1.5	-0.2	-0.2	-1.1	-0.6	-0.4	-0.3	0.5	-0.1	-0.1	-1.2	-0.7	0.4	-0.4	-0.0
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	4.8	-0.0	0.8	-0.6	0.0	-1.8	-0.1	-0.4	-2.2	-1.3	0.4	-0.9	0.3	-0.5	0.4
Glaucoma (self-reported)	0.9	1.1	3.7	0.8	0.9	0.5	0.6	1.9	0.3	0.6	1.8	1.7	1.0	1.1	0.2	0.7	0.7
Gout (self-reported)	0.5	0.7	2.3	-0.6	-0.2	1.0	-1.4	0.7	0.7	0.5	1.0	0.9	-0.5	1.5	-0.1	0.5	0.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.0	0.3	0.9	-1.2	1.7	-0.0	-0.6	1.1	-0.7	-1.1	-1.0	-0.2	1.0	-0.7	0.8
Medication: Amlodipine	1.1	1.5	4.0	-0.2	0.0	-1.4	-0.0	-0.8	-1.7	0.9	-1.3	-1.6	-1.6	-2.0	1.0	-1.6	0.9
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.0	0.6	1.0	0.3	-0.0	0.2	0.7	0.3	0.3	0.2	0.6	0.1	0.4	-0.2	-0.0
Birth weight	0.1	0.2	0.7	0.2	0.3	-0.6	0.7	0.5	-0.0	0.6	0.2	0.1	-0.8	0.9	0.3	0.3	0.1
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.7	-0.1	0.7	0.1	-0.2	-0.6	-0.1	-0.7	0.5	0.5	1.3	0.3	-0.4	1.1	-0.1
High blood pressure (siblings)	0.8	1.2	4.9	-1.3	0.0	-0.0	0.4	1.4	0.8	0.2	2.2	1.9	0.6	1.2	-0.4	1.2	-0.2
Forced vital capacity (FVC), Best measure	2.5	9.0	21.4	0.9	2.6	-3.8	0.4	0.7	-3.7	4.6	0.5	-1.9	-2.9	-2.1	4.0	-4.0	4.4
Body fat percentage	0.9	3.5	9.7	1.8	3.1	-2.3	-0.2	-0.2	-2.1	2.0	-1.0	-1.4	-1.7	-1.0	2.5	-2.2	2.0
Leg fat percentage (right)	0.3	1.1	4.6	1.9	2.1	-1.2	0.2	-0.3	-0.8	0.8	-0.4	-0.3	-0.3	-0.3	1.3	-1.0	0.7
Arm fat-free mass (right)	0.1	0.7	8.1	2.9	-0.8	-0.1	-0.9	-0.0	-0.1	0.1	0.2	0.5	-0.3	0.2	-0.1	-0.5	-0.1
Exposure to tobacco smoke outside home	0.9	1.2	4.3	1.0	2.1	-0.6	1.5	0.8	-0.3	1.5	-0.2	0.4	-0.7	1.3	1.2	-0.1	1.2
Comparative body size at age 10	0.7	2.0	4.0	-0.4	1.8	-1.4	-0.5	-1.8	-1.3	1.5	-0.8	-1.7	-1.1	-0.7	2.0	-1.6	1.8
Number of full brothers	0.5	0.7	2.1	0.8	-1.4	0.3	-0.6	-0.4	-0.2	-1.0	-1.5	-0.4	-0.1	-1.1	-0.4	-0.4	-1.1
Worry too long after embarrassment	2.1	3.6	8.0	-0.6	1.8	-2.3	0.7	-1.2	-2.0	2.0	-1.2	-2.0	-1.9	-2.2	2.2	-2.3	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.3	2.9	5.9	1.6	1.7	-1.0	-2.4	-2.4	-1.8	1.1	-1.5	-2.0	-0.8	-1.1	1.7	-1.4	2.4
Wheeze or whistling in the chest in last year	0.2	0.4	2.5	1.6	0.3	0.9	-0.0	0.6	0.8	-0.2	-0.2	-0.3	0.7	0.2	-0.1	0.3	-0.0
Number of children fathered	0.7	0.7	4.0	2.0	1.0	-0.8	-0.6	-0.4	-1.6	0.4	-0.1	-0.5	-0.8	-0.3	0.4	0.1	0.5
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.8	6.5	0.2	2.2	-1.9	1.0	0.7	-1.9	2.5	0.6	-1.0	-1.9	-1.1	2.1	-1.9	2.3
Age at first live birth	0.5	0.9	2.9	-0.1	-1.7	0.8	0.4	0.5	-0.3	-1.4	-1.2	-0.1	-0.6	-0.0	-1.4	-0.1	-1.6
Pulse wave peak to peak time	0.6	0.7	1.6	-0.5	0.5	-0.9	1.1	-0.6	-0.6	1.2	0.3	-0.7	-1.1	-0.3	1.2	-1.0	0.8
Health satisfaction	0.2	0.3	1.8	-0.2	0.8	0.8	-1.3	-0.4	0.5	-0.1	0.0	0.3	0.6	0.6	-0.1	0.4	-0.2
Shortness of breath walking on level ground	1.2	1.4	4.5	1.2	0.4	-0.2	-2.1	-2.1	0.2	-0.8	-1.9	-1.6	0.5	-1.2	0.1	-0.5	-0.1
Qualifications: College or University degree	0.2	0.5	2.5	-0.7	-0.9	-0.3	1.6	1.2	0.1	-0.4	0.5	1.0	0.2	0.1	-0.7	0.5	-0.3
Eye problems/disorders: None of the above	0.3	0.4	2.5	0.5	-0.2	-0.5	-0.4	-0.1	-0.8	0.3	-0.7	-0.5	-1.6	-0.2	0.4	-0.7	-0.1
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.0	1.3	1.7	-0.1	-0.5	-1.2	-0.8	0.8	-0.1	-1.0	0.7	-0.8	0.9	-0.7	1.3
Emphysema/chronic bronchitis	2.0	2.3	7.7	0.4	-1.4	2.2	0.6	0.8	2.8	-1.6	0.2	0.9	1.8	1.1	-1.8	1.6	-1.5
Medication for pain relief, constipation, heartburn	0.5	0.8	2.1	-0.2	-1.0	0.8	1.2	1.1	0.1	-1.1	0.1	0.5	0.2	0.5	-1.4	1.1	-1.1
Neck or shoulder pain in last month	0.3	0.4	1.7	1.3	0.8	-1.3	0.2	-0.6	0.3	0.6	0.7	0.0	0.0	0.1	0.5	0.3	0.8
Medication: Blood pressure	0.6	1.1	5.6	-0.1	-0.9	0.5	-0.3	1.9	0.1	0.4	2.4	1.8	-0.2	1.0	-0.4	0.5	-0.5
Angina (self-reported)	0.4	0.5	2.7	0.3	-0.0	0.7	0.3	-0.4	1.6	-0.9	-0.0	0.8	1.0	0.6	-0.6	0.9	-0.6
Migraine (self-reported)	0.4	0.5	2.7	-0.3	-0.2	-1.2	1.6	-0.1	-0.6	0.4	-0.5	-0.5	-0.7	-1.1	0.5	-0.8	-0.1
Medication: Ibuprofen	0.8	0.9	2.0	0.8	-1.1	0.8	-1.4	0.4	0.8	-0.3	0.9	1.4	-0.1	1.3	-0.8	0.9	-1.1
Medication: Allopurinol	0.6	0.9	2.9	-0.3	-0.2	1.0	-0.6	1.1	1.1	0.5	1.4	1.5	-0.2	1.7	-0.2	0.7	0.3
Medication: Omeprazole	0.8	1.0	5.4	1.2	0.0	0.3	-2.3	-1.5	0.4	-0.9	-0.3	0.1	1.6	-0.6	-0.3	-0.2	-0.2
Medication: Seretide 50 evohaler	0.7	0.9	2.1	0.9	-0.3	0.7	-0.5	0.1	1.4	-1.1	0.2	0.7	1.3	0.9	-1.1	1.4	-1.0
Mean time to correctly identify matches	2.8	5.3	9.1	1.1	2.6	-1.7	-1.6	-2.9	-1.7	2.1	-1.8	-3.0	-1.3	-2.5	2.8	-3.0	2.7
Heart disease (mother)	1.1	1.3	2.4	1.1	1.4	-0.5	1.6	-1.1	-1.4	1.2	-1.0	-1.0	-0.5	-0.6	1.4	-1.4	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	1.1	-0.1	0.7	-1.2	-1.2	0.4	-0.4	-1.0	-0.9	1.0	-0.8	-0.3	-0.3	0.3
Whole body fat mass	0.7	3.0	6.9	2.6	2.6	-2.2	-0.5	0.1	-2.0	1.9	-0.5	-0.9	-1.6	-0.7	2.1	-1.9	1.7
Leg fat mass (right)	0.5	1.8	8.8	3.0	2.1	-1.6	-0.3	-0.2	-1.2	1.2	-0.4	-0.3	-0.6	-0.5	1.5	-1.4	1.1
Arm predicted mass (right)	0.1	0.7	7.4	2.7	-0.5	0.0	-0.9	0.2	-0.0	0.2	0.3	0.6	-0.1	0.3	0.0	-0.5	-0.0
Pulse rate, automated reading	0.4	1.4	3.8	-1.1	0.8	-1.4	-0.3	1.1	-0.9	2.0	-0.4	-0.9	-1.8	-0.3	1.6	-1.4	1.3
Alcohol intake frequency.	1.7	3.8	8.5	1.9	0.5	-1.5	-2.6	-2.9	-1.3	0.3	-2.7	-2.3	-0.3	-2.9	1.4	-2.1	1.7
Comparative height size at age 10	0.5	2.7	11.6	3.4	1.1	-1.2	-1.7	-0.2	-1.2	2.3	2.0	0.8	-1.0	0.9	1.5	-1.1	2.0
Number of full sisters	0.7	0.9	2.8	1.0	-1.7	0.4	0.1	0.9	0.8	-1.0	0.5	0.8	1.1	0.2	-1.1	0.5	-1.6
Suffer from ‘nerves’	0.5	0.7	2.8	-0.1	-1.7	0.2	0.0	1.4	0.3	0.6	1.7	0.2	-1.4	0.5	-0.2	0.4	-0.3
Overall health rating	0.2	0.4	2.3	0.4	-0.1	0.2	-0.8	-1.5	0.8	-0.5	-0.6	-0.5	0.3	0.1	-0.3	0.5	-0.5
Chest pain or discomfort	0.5	0.7	2.4	0.9	-0.1	0.4	0.7	-0.6	1.6	-0.9	-1.4	-0.6	1.2	-0.4	-0.6	0.4	-0.3
Had major operations	2.0	2.3	5.9	0.6	0.1	-2.1	-1.3	-1.4	-2.3	1.1	-0.4	-1.5	-1.9	-2.4	1.2	-1.7	1.2
Age at last live birth	1.9	2.8	11.0	1.1	-3.3	1.1	-0.2	-0.2	0.4	-2.6	-2.1	-0.2	-0.5	-0.2	-2.3	0.5	-2.8
Family relationship satisfaction	1.3	1.6	5.1	-0.4	-0.1	2.3	-2.0	-1.3	1.8	-1.0	-1.4	0.4	1.8	0.8	-0.6	0.1	-0.3
Leg pain on walking	1.5	1.8	4.7	1.1	-0.9	1.2	-0.0	-0.1	1.4	-1.5	1.0	1.8	1.3	1.5	-1.5	1.8	-2.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.5	-1.2	0.5	0.2	-0.9	-0.3	-0.2	0.6	-0.5	-0.8	-0.6	-0.4	0.7	-1.0	0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.8	1.2	0.1	1.1	0.2	-1.3	0.3	-0.4	-0.2	0.1	1.0	0.6	-0.3	0.4	0.1
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.7	0.3	1.6	-1.3	-0.5	-1.9	-1.2	0.7	-0.0	-1.4	-0.6	-1.1	0.9	-0.8	1.5
Medication: Aspirin	0.6	0.7	1.6	-0.3	0.7	-0.9	0.7	-1.3	-0.7	0.9	0.5	-0.8	-0.2	-1.2	1.2	-1.1	0.9
Supplements: Vitamin C	0.5	0.6	2.3	-0.5	0.9	-0.7	0.7	0.8	-0.5	1.3	1.5	-0.1	-0.8	0.0	0.8	-0.5	0.8
Knee pain experienced in last month	1.3	2.0	3.9	0.2	1.8	-1.6	0.7	-0.8	-1.9	1.7	-1.0	-1.1	-1.6	-0.5	2.0	-1.5	1.5
Hypertension (Self-reported)	0.2	0.6	2.7	0.8	0.1	-0.6	-0.2	1.0	-1.0	1.2	1.7	0.7	-0.8	0.2	0.6	-0.4	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.6	0.4	0.8	-1.1	-0.8	-1.9	-0.3	0.5	-0.7	-0.8	0.2	-1.3	0.9	-0.7	1.0
Illnesses of father: Heart disease	0.3	0.5	2.5	-1.6	0.4	0.3	0.7	-1.2	0.1	-0.5	-0.5	-0.0	1.1	-0.1	-0.0	0.2	0.4
Illnesses of siblings: Diabetes	1.4	1.8	4.7	2.2	1.5	-0.7	-1.9	-1.0	-1.0	1.2	-1.0	-1.5	-0.5	-1.0	1.4	-1.4	1.3
Smoking status: Previous	0.7	1.1	5.1	1.5	2.3	-0.2	-0.1	0.2	-0.4	1.1	0.7	-0.4	0.5	-0.5	1.2	-0.4	1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	8.3	0.4	-0.5	1.0	0.5	2.9	1.4	-0.4	2.3	2.7	1.1	2.4	-1.2	1.7	-0.8
Whole body fat-free mass	0.2	1.0	10.4	3.2	-0.4	-0.6	-0.2	0.0	-0.8	0.5	-0.0	0.3	-0.7	-0.2	0.3	-0.9	0.1
Leg fat-free mass (right)	0.3	1.4	8.8	3.0	0.3	-1.2	-0.1	-0.0	-1.3	0.8	-0.9	-0.5	-1.2	-0.8	0.8	-1.5	0.8
Arm fat percentage (left)	1.0	4.1	9.7	2.0	3.1	-2.5	0.4	-0.7	-2.2	2.0	-1.4	-1.8	-1.6	-1.7	2.6	-2.3	2.1
Average weekly red wine intake	0.5	0.7	3.4	0.2	1.8	-0.7	-0.5	0.1	-0.5	1.2	-0.0	0.2	-0.9	0.4	1.2	-0.5	0.9
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.9	-0.1	0.0	-0.6	-0.4	0.2	0.0	-0.4	0.1	-0.1	-0.2	-0.0	-0.5	0.1	-0.9
Mood swings	0.1	0.2	1.1	-0.4	1.1	-0.2	-0.5	-0.2	0.7	0.1	-0.6	0.1	0.4	-0.3	0.3	-0.0	0.5
Loneliness, isolation	0.6	0.9	3.4	0.1	-1.1	0.7	-1.1	-1.1	0.2	-0.9	-1.8	-1.3	-0.2	-1.0	-0.4	-0.3	-0.7
Long-standing illness, disability or infirmity	0.3	0.5	3.7	1.9	-0.3	0.5	-0.6	-0.3	0.9	-0.3	0.2	0.6	0.5	0.6	-0.3	0.1	-0.5
Ever had bowel cancer screening	1.1	1.3	5.6	0.3	2.4	-0.9	0.1	1.1	-0.5	1.6	1.5	0.7	0.5	0.7	1.2	-0.6	1.4
Diabetes diagnosed by doctor	1.0	1.7	7.3	0.9	1.4	-0.7	2.7	1.5	0.6	0.9	2.2	1.4	0.5	1.4	0.7	0.4	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.8	-0.7	0.2	0.6	-0.6	-0.8	0.0	-0.5	-0.9	0.0	0.3	-0.3	-0.2	-0.1	-0.1
Friendships satisfaction	0.7	0.9	3.2	-0.8	0.1	0.1	-1.8	-1.5	-0.0	0.1	-1.8	-1.0	-0.6	-0.5	0.4	-1.0	0.6
Qualifications: nursing, teaching	0.3	0.5	2.9	-0.5	-0.1	-0.2	0.5	-0.8	-1.2	-0.6	-1.7	-0.9	-0.2	-0.5	-0.2	-0.3	0.5
Commuting to job workplace: Walk	0.3	0.3	1.1	0.5	-0.5	-0.8	1.0	0.9	0.5	0.3	0.4	-0.0	-1.0	-0.4	0.2	-0.2	-0.3
Eye problems/disorders: Cataract	0.5	0.6	1.6	-0.3	-0.1	0.6	0.2	1.0	1.0	-0.6	0.6	1.0	1.2	1.1	-0.7	0.7	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	3.8	-1.4	0.3	-0.0	2.0	1.0	-0.4	0.4	0.1	-0.2	-0.5	-0.6	0.2	-0.1	0.2
Medication for cholesterol	0.4	0.6	2.3	1.3	0.7	-0.2	-0.3	0.8	-0.3	1.1	-0.1	-0.4	-0.6	-0.1	1.0	-0.6	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	-0.5	-0.4	0.7	-0.6	0.2	0.4	-0.0	-0.7	0.1	0.1	0.7	-0.0	0.0	-0.4
Back pain experienced in last month	1.3	2.0	6.2	2.0	-0.2	1.3	-0.4	0.0	2.0	0.1	2.0	2.2	0.7	2.5	-0.3	1.5	-0.3
Mineral and other dietary supplements	1.5	2.0	6.1	0.4	-1.4	1.7	-2.1	-1.5	1.2	-1.9	-2.5	-0.7	0.8	0.0	-1.3	0.8	-1.4
Breast cancer (self-reported)	0.5	0.6	3.2	-0.8	0.5	0.5	0.7	0.9	1.8	-0.6	-0.0	0.1	1.0	0.7	-0.7	0.7	-0.3
Asthma (self-reported)	0.9	1.8	4.2	1.5	2.1	-1.0	-0.5	-0.0	-1.3	1.5	-1.1	-1.3	-1.0	-1.3	2.0	-1.7	1.1
Osteoporosis (self-reported)	0.3	0.4	2.4	-0.7	0.2	-0.4	-0.2	0.1	-0.4	0.4	1.5	1.0	-0.0	1.1	0.1	0.4	-0.2
Osteoarthritis (self-reported)	0.5	0.7	1.6	1.3	-0.9	1.2	-0.6	0.1	0.7	-0.4	0.7	1.0	0.7	1.1	-0.5	0.5	-0.9
Medication: Aspirin	1.1	1.4	3.2	-0.7	1.3	-1.3	1.5	-0.7	-1.1	1.7	0.9	-0.6	-0.5	-1.1	1.8	-1.5	1.3
Medication: Gliclazide	2.9	3.3	12.1	0.7	-0.3	1.4	1.1	0.6	3.5	-1.8	0.7	1.9	2.1	2.7	-2.0	2.3	-1.5
Illnesses of father: None of the above (group 1)	0.1	0.2	1.2	1.1	-0.6	-0.1	-0.5	0.3	-0.3	0.2	-0.1	-0.2	-0.2	0.0	0.2	-0.5	-0.1
Smoking status: Current	0.6	1.0	2.9	1.0	-1.7	1.2	-0.3	-0.5	0.8	-1.1	-1.7	-0.7	-0.4	-0.0	-0.7	-0.1	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.6	9.7	18.1	-0.5	2.8	-3.4	1.2	-0.4	-4.1	4.0	-1.0	-3.1	-3.4	-3.0	4.1	-4.3	4.0
Whole body water mass	0.2	1.0	10.8	3.3	-0.3	-0.6	-0.3	-0.0	-0.8	0.5	0.0	0.3	-0.7	-0.1	0.4	-1.0	0.2
Leg predicted mass (right)	0.3	1.5	8.7	2.9	0.4	-1.2	-0.2	-0.0	-1.4	0.8	-1.0	-0.6	-1.3	-0.8	0.9	-1.6	0.9
Arm fat mass (left)	0.6	2.6	6.5	2.5	2.1	-1.9	0.1	-0.2	-1.9	1.7	-0.8	-1.1	-1.5	-1.1	2.0	-2.0	1.6
Number of self-reported non-cancer illnesses	0.4	0.7	2.5	0.4	1.0	-1.2	0.3	-0.2	-0.6	1.6	1.0	-0.2	-0.2	0.1	1.3	-0.5	1.1
Average weekly champagne plus white wine intake	0.8	1.1	3.2	0.6	-1.1	1.0	0.3	0.7	0.2	-0.8	0.6	1.8	0.0	1.8	-1.3	1.3	-1.3
Miserableness	0.7	1.2	4.6	0.2	-0.3	-0.5	0.1	-1.0	-0.0	-0.0	-2.1	-2.0	-1.1	-1.9	0.5	-1.3	0.6
Guilty feelings	0.7	1.0	4.1	1.5	0.2	0.7	-1.0	-1.7	-0.5	-0.3	-2.0	-1.4	-0.2	-0.7	0.0	-0.4	0.5
Wears glasses or contact lenses	1.4	1.7	3.7	-0.3	1.9	-1.5	0.0	-0.6	-1.3	1.6	-0.4	-1.4	-0.6	-1.4	1.7	-1.4	1.9
Ever taken oral contraceptive pill	1.0	1.1	3.8	0.2	0.4	-1.1	-0.2	0.7	-1.2	1.6	1.8	0.5	-1.9	-0.1	1.1	-0.7	0.4
Hearing aid user	2.3	2.6	7.7	1.0	1.6	-2.8	-0.7	-0.3	-2.4	1.8	-0.0	-0.8	-2.0	-1.6	1.9	-1.7	1.5
Mother’s age at death	2.0	2.6	7.1	1.2	2.7	-1.2	0.5	0.3	-1.4	2.5	-0.8	-1.0	-1.9	-0.2	2.3	-1.8	1.9
Financial situation satisfaction	0.2	0.2	1.2	0.2	-0.4	0.4	-0.8	-1.1	0.3	-0.4	-0.5	0.1	0.1	0.1	-0.2	0.3	-0.3
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.7	-1.3	-0.1	-0.9	1.2	-0.2	-1.1	0.7	-0.1	-0.4	-1.2	-1.0	0.8	-0.8	0.3
Commuting to job workplace: Public transport	0.5	0.6	1.3	1.0	-0.7	0.2	-0.5	1.1	0.2	-0.6	1.0	0.8	-0.3	0.3	-0.8	0.9	-1.1
Eye problems/disorders: Glaucoma	1.1	1.2	3.3	-0.2	1.7	-0.2	1.2	1.5	-0.5	1.4	1.8	1.2	0.6	0.3	1.2	-0.3	1.4
Medication: Blood pressure	0.3	0.5	1.4	-0.4	0.0	-1.1	0.9	-0.9	-1.2	0.2	-0.5	-0.7	-0.8	-1.1	0.5	-0.6	-0.3
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.1	0.5	0.1	0.7	-1.2	-0.9	1.4	-0.4	0.1	0.1	1.4	0.5	-0.3	0.7	-0.2
Supplements: Fish oil (including cod liver oil)	1.1	1.5	4.2	-0.1	2.0	-1.2	1.2	0.8	-0.9	1.7	2.0	0.4	-0.1	0.5	1.1	-0.4	1.7
High cholesterol (Self-reported)	0.2	0.3	1.3	0.3	0.7	0.0	-0.6	-0.4	0.3	0.6	1.2	0.4	0.4	0.7	0.5	0.4	0.2
Medication: Bendroflumethiazide	0.5	0.7	2.9	0.8	0.9	-1.2	0.8	-0.0	-1.0	0.7	-0.1	-1.1	-1.7	-0.3	0.7	-0.3	0.3
Medication: Paracetamol	0.6	1.0	2.7	0.6	0.7	-0.9	-1.5	0.8	-0.5	1.6	0.9	0.2	-1.3	0.6	1.4	-0.7	0.7
Medication: Lisinopril	0.4	0.6	2.2	-0.4	0.2	-0.6	-1.1	1.2	-1.0	0.9	0.1	0.5	-1.5	0.3	0.5	-0.2	0.3
Medication: Atorvastatin	0.2	0.2	0.6	-0.1	-0.8	-0.1	0.6	-0.8	-0.0	-0.4	0.0	0.0	-0.1	-0.8	-0.1	-0.3	-0.4
Illnesses of father: High blood pressure	1.2	1.5	3.9	-1.3	-1.5	1.0	-0.1	-0.3	1.9	-1.3	1.0	0.9	0.5	1.0	-1.7	2.0	-1.1
Alcohol drinker status: Never	0.4	0.5	1.6	1.1	0.1	0.6	0.8	-0.4	1.3	-0.2	-1.1	-0.1	0.9	0.2	0.1	-0.7	0.3
Ever smoked	0.4	0.6	2.4	0.8	1.6	-0.2	-0.4	0.1	-0.9	1.1	-0.1	-0.6	-0.2	-0.5	1.2	-0.7	1.0
Basal metabolic rate	0.2	1.1	11.2	3.3	-0.0	-0.8	-0.3	0.0	-0.9	0.6	-0.2	0.1	-0.8	-0.2	0.6	-1.1	0.3
Leg fat percentage (left)	0.4	1.3	5.9	1.3	2.4	-1.4	-0.1	-0.2	-1.2	1.0	-0.5	-0.6	-0.5	-0.5	1.4	-1.2	1.1
Arm fat-free mass (left)	0.2	0.8	8.8	3.0	-0.5	-0.0	-0.5	0.5	-0.3	0.3	0.4	0.7	-0.4	0.4	0.1	-0.6	-0.1
Number of operations (self-reported)	0.9	1.4	3.2	0.3	0.7	-1.8	0.5	-0.6	-1.5	1.7	0.7	-0.6	-1.8	-1.4	1.4	-1.3	1.1
Average weekly beer plus cider intake	0.4	0.6	3.6	-0.1	0.2	1.0	-0.2	0.5	1.1	-0.6	-0.6	0.5	1.9	1.0	-0.3	0.4	-0.5
Irritability	0.1	0.2	0.7	-0.9	-0.0	0.3	-0.7	-0.2	-0.5	0.1	0.2	-0.2	-0.4	-0.5	0.1	-0.3	-0.0
Risk taking	1.0	1.5	2.9	0.8	1.1	-1.5	-0.3	-0.4	-1.4	1.6	0.1	-0.4	-1.4	-1.6	1.7	-1.6	1.2
Ever had prostate specific antigen (PSA) test	1.4	1.6	4.0	1.2	0.3	-1.5	-0.1	-0.8	-1.7	1.4	-0.3	-0.8	-2.0	-1.8	1.3	-1.6	1.2
Fractured/broken bones in last 5 years	0.1	0.2	0.4	-0.6	0.1	0.0	-0.4	0.6	0.4	0.5	0.3	-0.5	0.1	0.5	0.2	-0.4	0.3
Age started oral contraceptive pill	0.1	0.1	0.5	-0.7	0.1	-0.1	0.3	0.2	-0.3	0.2	-0.1	-0.1	-0.5	-0.2	0.2	-0.5	-0.3
Diastolic blood pressure, automated reading	0.7	2.2	4.9	-1.9	2.2	-1.6	0.3	1.6	-1.6	2.1	0.6	-0.1	-0.5	-0.0	2.0	-1.5	1.7
Ever depressed for a whole week	1.1	1.4	4.3	0.7	2.1	-1.3	0.8	0.1	-0.4	1.6	-0.1	-1.1	-1.2	-0.8	1.7	-1.1	1.5
Unable to work because of sickness or disability	0.8	1.1	2.7	0.3	-0.6	0.7	-0.7	-0.4	1.0	-1.1	0.3	1.3	1.0	1.6	-1.3	1.7	-1.2
Commuting to job workplace: Cycle	1.0	1.2	4.1	-0.2	-2.0	0.8	0.7	0.2	1.1	-1.8	-0.5	0.1	0.0	0.3	-1.9	1.1	-1.5
Myopia	1.5	2.2	7.6	-0.4	-0.6	1.1	0.2	-0.8	1.9	-2.2	-0.1	0.8	2.8	0.8	-2.0	2.0	-1.7
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.1	-0.7	1.1	-0.2	-0.6	-1.1	-0.2	-0.1	-1.4	-1.1	0.4	-0.6	0.5	-0.5	0.6
Cholesterol lowering medication	0.3	0.4	1.8	-0.7	0.1	0.6	-0.5	-1.3	0.4	-0.5	-0.6	-0.5	1.1	-0.0	-0.1	0.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	7.0	0.8	-0.1	0.6	-2.6	-1.6	0.6	-1.0	0.1	0.3	2.1	-0.4	-0.3	0.1	-0.3
Pain experienced in last month	0.5	0.8	2.3	-1.5	-0.8	0.9	0.5	1.5	0.2	-1.0	0.2	0.5	0.6	0.3	-1.2	0.7	-0.8
Supplements: Calcium	1.5	1.7	6.0	-1.2	-0.5	-0.7	2.3	1.8	-0.5	1.0	2.5	1.5	-1.4	0.7	0.2	0.1	-0.2
Basal cell carcinoma (self-reported)	0.7	0.8	6.1	-0.5	0.2	0.1	0.4	1.1	-0.3	0.6	2.5	1.2	-0.2	0.9	0.1	0.6	-0.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.5	-0.5	-1.2	1.4	0.2	-1.1	1.9	-1.5	-0.0	0.5	1.4	0.5	-1.5	1.2	-1.0
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	6.8	1.1	-1.3	1.5	-0.6	-0.9	1.7	-2.2	-0.0	0.8	2.6	0.7	-1.8	1.6	-1.1
Heart disease (siblings)	1.1	1.3	2.4	-1.5	1.1	-1.2	0.5	1.2	-1.3	1.6	1.2	0.3	-0.6	-0.8	1.6	-1.0	1.2
Alcohol drinker status: Previous	0.7	0.8	5.4	0.8	0.3	0.0	-1.4	-2.3	-0.3	-0.6	-1.0	-0.5	0.7	-0.5	-0.0	-0.3	0.4
Pack years of smoking	0.4	0.6	2.3	0.3	-1.1	-0.0	-0.3	-1.1	-0.0	-0.5	-1.5	-1.1	-0.3	-1.1	-0.4	-0.2	-0.5
Impedance of whole body	0.1	0.6	3.4	-1.9	0.6	-0.6	0.1	1.2	0.1	0.8	1.2	0.3	-0.6	0.8	0.3	0.2	0.4
Leg fat mass (left)	0.5	1.9	6.4	2.5	2.2	-1.7	-0.5	-0.2	-1.4	1.2	-0.6	-0.5	-0.8	-0.7	1.6	-1.5	1.2
Arm predicted mass (left)	0.2	0.9	9.6	3.1	-0.4	-0.4	-0.3	0.3	-0.6	0.6	0.2	0.3	-0.8	0.1	0.4	-0.9	0.2