Best TWAS P=2.73e-28 · Best GWAS P=2.01e-117 conditioned to 1.13e-44
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NWD1 | 0.47 | 0.33 | lasso | 3 | 0.33 | 6.5e-42 | 5.379 | -6.1 | 1.2e-09 | 0.11 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | C19orf44 | 0.21 | 0.14 | lasso | 5 | 0.13 | 1.7e-06 | -4.904 | 7.1 | 1.1e-12 | -0.05 | 0.64 | 0.03 | FALSE |
| 3 | GTEx | Muscle Skeletal | CTC-429P9.2 | 0.12 | 0.03 | lasso | 8 | 0.04 | 3.4e-05 | -0.081 | 7.1 | 1.1e-12 | -0.26 | 0.20 | 0.74 | TRUE |
| 4 | GTEx | Muscle Skeletal | CTC-429P9.3 | 0.10 | 0.00 | enet | 22 | 0.00 | 1.2e-01 | -0.073 | -7.7 | 1.6e-14 | 0.00 | 0.10 | 0.10 | TRUE |
| 5 | GTEx | Nerve Tibial | C19orf44 | 0.28 | 0.24 | enet | 11 | 0.25 | 4.5e-18 | -4.821 | 6.0 | 2.3e-09 | -0.07 | 1.00 | 0.00 | TRUE |
| 6 | METSIM | Adipose | C19orf44 | 0.12 | 0.15 | enet | 18 | 0.15 | 5.0e-22 | -4.904 | 5.6 | 1.7e-08 | -0.09 | 1.00 | 0.00 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | C19orf44 | 0.16 | 0.12 | enet | 6 | 0.12 | 3.2e-07 | -5.070 | 5.3 | 1.0e-07 | -0.03 | 0.97 | 0.01 | FALSE |
| 8 | The Cancer Genome Atlas | Glioblastoma Multiforme | MED26 | 0.16 | 0.01 | blup | 93 | 0.05 | 1.1e-02 | 9.648 | -9.4 | 7.6e-21 | 0.11 | 0.01 | 0.41 | TRUE |
| 9 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C19orf44 | 0.22 | 0.19 | blup | 44 | 0.20 | 9.4e-22 | -5.070 | 6.0 | 2.1e-09 | -0.06 | 1.00 | 0.00 | TRUE |
| 10 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C19orf44 | 0.07 | 0.02 | lasso | 2 | 0.01 | 2.7e-02 | -5.466 | 6.0 | 2.3e-09 | -0.18 | 0.12 | 0.04 | TRUE |
| 11 | The Cancer Genome Atlas | Thyroid Carcinoma | CHERP | 0.03 | 0.00 | blup | 51 | 0.01 | 2.8e-02 | 4.240 | 6.8 | 9.1e-12 | 0.00 | 0.02 | 0.21 | TRUE |
| 12 | The Cancer Genome Atlas | Thyroid Carcinoma | NWD1 | 0.13 | 0.06 | lasso | 1 | 0.05 | 4.6e-06 | 5.379 | -5.4 | 7.5e-08 | 0.06 | 0.00 | 1.00 | FALSE |
| 13 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | EPS15L1 | 0.17 | 0.05 | lasso | 5 | 0.06 | 8.1e-03 | 9.284 | -11.0 | 2.7e-28 | -0.02 | 0.02 | 0.04 | TRUE |