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chr1:212,274,413-213,728,049

Best TWAS P=7.49e-11 · Best GWAS P=1.27e-11 conditioned to 0.0205

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Coronary	FLVCR1-AS1	0.43	0.45	lasso	12	0.44	2.8e-16	-5.0	5.2	1.9e-07	-0.69	0.68	0.32	FALSE
2	GTEx	Artery Coronary	TATDN3	0.22	0.04	lasso	11	0.07	2.2e-03	-6.1	-5.4	8.0e-08	0.74	0.05	0.80	FALSE
3	GTEx	Brain Hypothalamus	FLVCR1-AS1	0.72	0.62	lasso	7	0.63	1.2e-18	-5.0	5.2	2.0e-07	-0.69	0.93	0.07	FALSE
4	GTEx	Breast Mammary Tissue	FLVCR1-AS1	0.45	0.44	enet	21	0.44	1.6e-24	-5.0	5.2	1.6e-07	-0.70	0.97	0.03	FALSE
5	GTEx	Breast Mammary Tissue (Male)	FLVCR1-AS1	0.52	0.39	lasso	8	0.44	2.2e-11	-6.2	5.9	4.5e-09	-0.83	0.09	0.91	FALSE
6	GTEx	Cells Transformed fibroblasts	TATDN3	0.11	0.12	lasso	2	0.10	3.2e-08	-6.2	-6.2	7.8e-10	0.92	0.05	0.95	FALSE
7	GTEx	Colon Sigmoid	FLVCR1-AS1	0.55	0.55	enet	11	0.49	1.8e-19	-5.0	5.2	2.1e-07	-0.74	0.93	0.07	FALSE
8	GTEx	Colon Transverse	TATDN3	0.26	0.02	lasso	7	0.02	2.8e-02	-6.4	-5.3	1.2e-07	0.64	0.05	0.93	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	TATDN3	0.27	0.08	enet	29	0.11	7.1e-05	-6.0	-5.6	2.2e-08	0.70	0.10	0.87	FALSE
10	GTEx	Esophagus Mucosa	FLVCR1-AS1	0.33	0.47	enet	16	0.46	4.7e-34	-5.0	5.1	3.0e-07	-0.72	0.97	0.03	FALSE
11	GTEx	Esophagus Muscularis	FLVCR1-AS1	0.52	0.53	enet	32	0.54	5.4e-38	-5.0	5.4	5.8e-08	-0.73	0.97	0.03	FALSE
12	GTEx	Heart Atrial Appendage	FLVCR1-AS1	0.56	0.61	enet	12	0.58	8.7e-32	-5.0	5.5	3.9e-08	-0.71	0.98	0.02	FALSE
13	GTEx	Lung	FLVCR1-AS1	0.42	0.50	lasso	5	0.52	4.9e-46	-5.0	5.5	3.4e-08	-0.75	0.97	0.03	FALSE
14	GTEx	Muscle Skeletal	FLVCR1-AS1	0.28	0.28	enet	22	0.27	1.3e-26	-5.0	5.3	1.3e-07	-0.69	0.97	0.03	FALSE
15	GTEx	Ovary	FLVCR1-AS1	0.47	0.20	enet	15	0.20	1.1e-05	-5.0	5.7	1.4e-08	-0.78	0.08	0.81	FALSE
16	GTEx	Prostate	FLVCR1-AS1	0.40	0.36	lasso	3	0.36	4.5e-10	-5.0	5.6	2.1e-08	-0.77	0.08	0.91	FALSE
17	GTEx	Spleen	FLVCR1-AS1	0.63	0.54	lasso	8	0.55	5.9e-17	-5.0	5.3	1.0e-07	-0.76	0.23	0.77	FALSE
18	GTEx	Stomach	FLVCR1-AS1	0.30	0.36	lasso	3	0.36	7.0e-18	-5.0	5.5	5.1e-08	-0.75	0.84	0.16	FALSE
19	GTEx	Thyroid	FLVCR1-AS1	0.48	0.44	lasso	7	0.46	8.8e-39	-5.0	5.1	2.8e-07	-0.73	0.97	0.03	FALSE
20	GTEx	Whole Blood	TATDN3	0.06	0.07	enet	6	0.07	1.2e-06	-6.4	-6.5	7.5e-11	0.86	0.02	0.98	TRUE
21	METSIM	Adipose	TATDN3	0.13	0.08	lasso	5	0.17	4.0e-25	-6.3	-5.3	1.1e-07	0.69	0.04	0.96	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	TATDN3	0.04	0.01	blup	49	0.01	1.1e-03	-6.8	-5.8	6.0e-09	0.75	0.00	0.98	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	LQK1	0.56	0.58	enet	11	0.59	4.5e-42	-5.0	5.1	2.9e-07	-0.70	0.97	0.03	FALSE
24	The Cancer Genome Atlas	Glioblastoma Multiforme	LQK1	0.61	0.45	enet	6	0.41	9.0e-14	-5.0	5.2	1.9e-07	-0.71	0.95	0.05	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	TATDN3	0.08	0.02	lasso	5	0.05	2.3e-06	-6.2	-5.7	9.6e-09	0.78	0.01	0.98	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	LQK1	0.57	0.62	lasso	8	0.63	9.6e-95	-5.1	5.1	2.9e-07	-0.71	0.97	0.03	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C1orf227	0.02	0.01	blup	48	0.01	1.5e-02	-5.0	6.1	1.2e-09	-0.84	0.02	0.68	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LQK1	0.55	0.59	enet	12	0.60	3.6e-50	-5.0	5.1	2.7e-07	-0.71	0.97	0.03	FALSE
29	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TATDN3	0.10	0.04	lasso	6	0.08	6.4e-04	-6.2	-6.1	1.4e-09	0.83	0.01	0.77	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	FLVCR1	0.09	0.03	blup	62	0.03	7.6e-04	-4.5	-5.3	1.5e-07	0.63	0.23	0.34	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	LQK1	0.57	0.62	enet	17	0.61	3.5e-55	-5.1	5.4	7.9e-08	-0.74	0.96	0.03	FALSE
32	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	LQK1	0.77	0.47	lasso	7	0.43	2.1e-13	-5.0	5.3	1.1e-07	-0.73	0.65	0.35	FALSE