Hub : Genes

FLVCR1-AS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.493 0.0540 0.0e+00 0.490 NA 0.491 NA 0.488 3.0e-45 NA 2.0e-45 NA 4.8e-45
2 GTEx Adipose Visceral Omentum 0.453 0.0590 0.0e+00 0.507 NA 0.469 NA 0.488 5.7e-30 NA 4.9e-27 NA 1.9e-28
3 GTEx Adrenal Gland 0.397 0.0838 7.6e-08 0.352 NA 0.290 NA 0.154 1.8e-13 NA 5.5e-11 NA 3.5e-06
4 GTEx Artery Aorta 0.571 0.0520 0.0e+00 0.570 NA 0.538 NA 0.344 1.3e-37 NA 1.4e-34 NA 1.0e-19
5 GTEx Artery Coronary 0.432 0.0700 8.1e-12 0.454 NA 0.392 NA 0.438 4.8e-17 NA 2.7e-14 NA 2.8e-16
6 GTEx Artery Tibial 0.450 0.0504 0.0e+00 0.462 NA 0.460 NA 0.472 4.1e-40 NA 8.6e-40 NA 3.4e-41
7 GTEx Brain Caudate basal ganglia 0.537 0.0810 1.1e-09 0.552 NA 0.512 NA 0.287 8.4e-19 NA 5.4e-17 NA 6.5e-09
8 GTEx Brain Cerebellar Hemisphere 0.529 0.1030 1.7e-06 0.496 NA 0.433 NA 0.142 1.1e-14 NA 2.0e-12 NA 1.7e-04
9 GTEx Brain Cerebellum 0.493 0.0830 3.4e-08 0.357 NA 0.330 NA 0.361 2.0e-11 NA 1.6e-10 NA 1.4e-11
10 GTEx Brain Cortex 0.718 0.0650 2.2e-13 0.616 NA 0.599 NA 0.610 3.1e-21 NA 2.3e-20 NA 6.1e-21
11 GTEx Brain Frontal Cortex BA9 0.688 0.0690 6.1e-10 0.558 NA 0.547 NA 0.150 1.1e-17 NA 3.4e-17 NA 8.6e-05
12 GTEx Brain Hippocampus 0.440 0.1043 8.1e-05 0.399 NA 0.355 NA 0.267 2.0e-10 NA 3.4e-09 NA 5.7e-07
13 GTEx Brain Hypothalamus 0.718 0.0800 1.6e-09 0.621 NA 0.606 NA 0.628 2.6e-18 NA 1.2e-17 NA 1.2e-18
14 GTEx Brain Nucleus accumbens basal ganglia 0.622 0.0800 2.4e-09 0.503 NA 0.327 NA 0.385 1.5e-15 NA 1.6e-09 NA 2.5e-11
15 GTEx Brain Putamen basal ganglia 0.350 0.0990 2.8e-04 0.399 NA 0.336 NA 0.329 1.5e-10 NA 8.6e-09 NA 1.3e-08
16 GTEx Breast Mammary Tissue 0.454 0.0590 1.7e-16 0.444 NA 0.438 NA 0.432 5.7e-25 NA 1.6e-24 NA 4.4e-24
17 GTEx Breast Mammary Tissue (Male) 0.518 0.0962 8.0e-08 0.389 NA 0.414 NA 0.436 4.9e-10 NA 9.8e-11 NA 2.2e-11
18 GTEx Breast Mammary Tissue (Female) 0.527 0.1006 7.1e-06 0.363 NA 0.232 NA 0.331 9.6e-12 NA 1.5e-07 NA 1.2e-10
19 GTEx Cells EBV-transformed lymphocytes 0.624 0.0660 1.2e-14 0.567 NA 0.575 NA 0.595 4.3e-22 NA 1.5e-22 NA 9.9e-24
20 GTEx Cells Transformed fibroblasts 0.536 0.0450 0.0e+00 0.603 NA 0.592 NA 0.602 3.5e-56 NA 1.7e-54 NA 5.0e-56
21 GTEx Colon Sigmoid 0.548 0.0720 1.7e-14 0.547 NA 0.487 NA 0.031 9.3e-23 NA 1.8e-19 NA 2.9e-02
22 GTEx Colon Transverse 0.518 0.0610 0.0e+00 0.557 NA 0.559 NA 0.554 2.4e-31 NA 1.4e-31 NA 4.2e-31
23 GTEx Esophagus Gastroesophageal Junction 0.535 0.0710 1.5e-14 0.560 NA 0.504 NA 0.529 4.7e-24 NA 8.2e-21 NA 3.0e-22
24 GTEx Esophagus Mucosa 0.328 0.0470 0.0e+00 0.466 NA 0.462 NA 0.190 1.7e-34 NA 4.7e-34 NA 9.7e-13
25 GTEx Esophagus Muscularis 0.524 0.0580 0.0e+00 0.531 NA 0.537 NA 0.534 1.9e-37 NA 5.4e-38 NA 1.1e-37
26 GTEx Heart Atrial Appendage 0.560 0.0610 0.0e+00 0.609 NA 0.585 NA 0.326 8.4e-34 NA 8.7e-32 NA 2.9e-15
27 GTEx Heart Left Ventricle 0.503 0.0589 0.0e+00 0.505 NA 0.513 NA 0.516 1.3e-30 NA 3.0e-31 NA 1.6e-31
28 GTEx Lung 0.421 0.0480 0.0e+00 0.505 NA 0.508 NA 0.521 4.1e-44 NA 1.9e-44 NA 4.9e-46
29 GTEx Muscle Skeletal 0.280 0.0468 0.0e+00 0.279 NA 0.271 NA 0.270 2.0e-27 NA 1.3e-26 NA 1.5e-26
30 GTEx Nerve Tibial 0.502 0.0559 0.0e+00 0.414 NA 0.417 NA 0.418 1.8e-31 NA 1.2e-31 NA 9.2e-32
31 GTEx Ovary 0.472 0.1050 2.5e-05 0.198 NA 0.201 NA 0.005 1.3e-05 NA 1.1e-05 NA 2.3e-01
32 GTEx Pituitary 0.718 0.0710 3.7e-11 0.576 NA 0.501 NA 0.529 1.5e-17 NA 1.5e-14 NA 1.3e-15
33 GTEx Prostate 0.397 0.0940 1.6e-05 0.362 NA 0.310 NA 0.365 5.4e-10 NA 1.5e-08 NA 4.5e-10
34 GTEx Skin Not Sun Exposed Suprapubic 0.607 0.0580 0.0e+00 0.517 NA 0.526 NA 0.522 1.6e-32 NA 2.7e-33 NA 6.0e-33
35 GTEx Skin Sun Exposed Lower leg 0.389 0.0510 0.0e+00 0.432 NA 0.443 NA 0.434 8.6e-39 NA 4.4e-40 NA 4.8e-39
36 GTEx Small Intestine Terminal Ileum 0.436 0.0970 6.7e-06 0.435 NA 0.443 NA 0.349 5.5e-11 NA 3.3e-11 NA 1.2e-08
37 GTEx Spleen 0.631 0.0790 3.0e-11 0.535 NA 0.524 NA 0.554 3.4e-16 NA 9.7e-16 NA 5.9e-17
38 GTEx Stomach 0.300 0.0560 2.6e-11 0.364 NA 0.311 NA 0.356 2.5e-18 NA 2.1e-15 NA 7.0e-18
39 GTEx Testis 0.295 0.0700 1.2e-06 0.226 NA 0.265 NA 0.129 2.2e-10 NA 3.7e-12 NA 2.4e-06
40 GTEx Thyroid 0.482 0.0520 0.0e+00 0.438 NA 0.456 NA 0.459 1.7e-36 NA 2.0e-38 NA 8.8e-39
41 GTEx Uterus 0.431 0.1130 1.7e-04 0.377 NA 0.221 NA 0.263 1.2e-08 NA 2.8e-05 NA 3.9e-06
42 GTEx Whole Blood 0.420 0.0490 0.0e+00 0.388 NA 0.436 NA 0.417 7.0e-38 NA 9.9e-44 NA 2.5e-41
43 METSIM Adipose 0.286 0.0385 0.0e+00 0.423 0.358 0.416 0.414 0.420 3.5e-69 4.7e-56 1.0e-67 3.2e-67 2.3e-68

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43
Bipolar Disorder (2018) 1.2 1.9 3.4 1.6 1.4 1.4 1.4 1.2 1.4 1.5 1.4 1.7 1.4 1.4 1.5 1.4 1.4 1.6 1.1 1.5 1.4 1.5 1.3 1.2 1.4 1.4 1.5 1.8 1.4 1.3 1.4 1.2 1.4 1.6 1.3 1.4 1.4 1.3 1.4 1.6 1.4 0.6 1.4 -0.7 1.1 1.4
Bipolar Disorder or Schizophrenia 0.6 1.3 3.1 1.2 1.1 0.2 1.1 1.0 1.0 1.1 1.1 1.3 1.2 1.0 1.1 1.1 1.4 1.1 1.1 1.4 1.1 1.3 1.0 1.1 0.9 1.1 1.3 1.8 1.2 1.2 1.1 1.1 1.3 1.5 1.2 1.2 1.4 1.0 1.1 1.3 1.2 0.2 1.3 -0.5 0.8 1.3
Depressed Affect (Nagel 2018) 0.0 0.1 0.7 -0.5 -0.2 -0.6 -0.2 -0.3 -0.2 -0.2 -0.2 -0.4 -0.2 -0.2 -0.2 -0.3 -0.1 -0.1 -0.3 -0.2 -0.2 -0.3 -0.2 -0.1 -0.3 -0.2 -0.3 -0.6 -0.2 -0.3 -0.1 -0.3 -0.4 -0.8 -0.2 -0.2 -0.4 -0.3 -0.2 -0.1 -0.2 -0.0 -0.3 0.0 -0.2 -0.3
Depression (Nagel 2018) 0.2 0.3 0.9 -0.6 -0.5 -0.5 -0.6 -0.5 -0.6 -0.5 -0.5 -0.7 -0.6 -0.5 -0.6 -0.6 -0.3 -0.3 -0.7 -0.2 -0.6 -0.7 -0.5 -0.4 -0.5 -0.5 -0.5 -0.8 -0.6 -0.6 -0.4 -0.5 -0.5 -0.5 -0.6 -0.3 -0.4 -0.3 -0.6 -0.5 -0.4 -0.9 -0.4 0.5 -0.9 -0.6
Intelligence (Savage-Jansen 2018) 1.6 4.9 7.1 2.5 2.3 1.9 2.3 2.6 2.4 2.4 2.3 2.3 2.4 2.5 2.3 2.7 2.0 1.9 1.6 1.8 2.3 2.5 2.3 2.1 2.1 2.3 2.2 1.7 2.5 2.4 2.2 2.6 2.2 2.3 2.2 2.0 2.0 2.1 2.2 1.7 2.1 1.8 2.0 -2.1 2.1 2.3
Neuroticism (Nagel 2018) 0.2 0.5 1.4 -1.1 -0.5 -1.2 -0.6 -0.6 -0.6 -0.5 -0.5 -0.7 -0.6 -0.6 -0.5 -0.5 -0.5 -0.5 -0.9 -0.6 -0.6 -0.7 -0.6 -0.7 -0.7 -0.5 -0.6 -0.8 -0.5 -0.6 -0.5 -0.6 -0.8 -1.0 -0.5 -0.5 -0.8 -0.7 -0.6 -0.5 -0.5 -0.5 -0.8 0.4 -1.2 -0.6
Schizophrenia (2018) 0.1 0.2 0.7 0.3 0.3 -0.8 0.3 0.3 0.1 0.2 0.3 0.4 0.4 0.1 0.2 0.3 0.7 0.1 0.4 0.6 0.3 0.5 0.3 0.5 0.0 0.4 0.5 0.8 0.4 0.5 0.3 0.4 0.5 0.7 0.5 0.5 0.7 0.1 0.3 0.4 0.4 -0.3 0.5 -0.1 0.1 0.5
Schizophrenia vs Biploar Disorder 0.1 0.1 0.7 -0.8 -0.1 -0.6 -0.2 -0.1 -0.4 -0.3 -0.2 -0.5 -0.2 -0.3 -0.3 -0.2 -0.1 -0.1 -0.3 -0.2 -0.2 -0.2 -0.2 -0.3 -0.2 -0.2 -0.3 -0.7 -0.2 -0.3 -0.1 -0.4 -0.2 -0.3 -0.3 -0.2 -0.4 -0.6 -0.3 -0.2 -0.2 -0.6 -0.2 -0.1 -0.7 -0.3
Worry (Nagel 2018) 0.2 0.4 2.1 -1.0 -0.5 -0.9 -0.6 -0.5 -0.6 -0.5 -0.5 -0.5 -0.5 -0.6 -0.5 -0.5 -0.4 -0.4 -0.8 -0.3 -0.5 -0.6 -0.5 -0.8 -0.8 -0.5 -0.5 -0.8 -0.6 -0.5 -0.4 -0.6 -0.6 -0.4 -0.6 -0.3 -0.7 -0.5 -0.6 -0.4 -0.4 -0.8 -0.5 0.6 -1.5 -0.5
Alzheimer’s Disease (in mother) 2.8 3.3 5.7 -1.7 -1.7 -1.9 -1.6 -1.9 -1.7 -1.6 -1.7 -1.5 -1.5 -1.5 -1.5 -2.0 -1.8 -1.4 -1.9 -2.3 -1.6 -1.4 -1.7 -1.9 -2.0 -1.8 -1.7 -2.1 -1.9 -1.8 -1.9 -1.8 -1.9 -2.4 -1.7 -2.1 -1.8 -1.6 -1.8 -1.8 -2.0 -2.1 -2.0 2.0 -1.9 -1.7
Alzheimer’s Disease (in father) 0.4 0.5 1.4 1.2 0.7 0.5 0.7 0.8 0.8 0.5 0.6 0.6 0.9 0.6 0.5 0.7 0.6 0.4 0.7 0.6 0.8 0.9 0.7 0.5 0.7 0.7 0.8 0.7 0.4 0.7 0.7 0.5 0.6 0.6 0.7 0.7 1.1 0.8 0.5 0.7 0.7 -0.3 0.6 -0.9 0.6 0.8
Alzheimer’s Disease (including proxy) 2.9 4.2 7.3 -1.8 -2.0 -2.4 -1.9 -2.1 -1.9 -1.8 -2.0 -2.2 -1.7 -1.8 -1.7 -2.1 -2.1 -1.9 -2.1 -2.5 -1.8 -1.7 -2.0 -2.1 -2.0 -2.0 -2.0 -2.3 -2.1 -2.0 -2.1 -1.9 -2.3 -2.7 -2.2 -2.3 -2.2 -1.9 -1.9 -2.0 -2.2 -2.1 -2.3 1.9 -2.2 -2.0
Crohns Disease (2017) 0.7 1.6 3.3 -1.0 -1.4 -0.6 -1.4 -1.3 -1.2 -1.5 -1.4 -1.8 -1.5 -1.4 -1.5 -1.4 -1.5 -1.4 -1.1 -1.1 -1.5 -1.7 -1.3 -1.1 -1.2 -1.4 -1.5 -0.7 -0.9 -1.3 -1.3 -1.0 -1.3 -1.1 -1.4 -1.3 -1.2 -1.3 -1.3 -1.3 -1.3 0.1 -1.2 0.6 -0.7 -1.5
Irritable Bowel Disease (IBD) 0.0 0.1 0.6 -0.2 -0.2 0.6 -0.2 -0.2 -0.1 -0.3 -0.2 -0.6 -0.4 -0.2 -0.3 -0.2 -0.5 -0.3 -0.0 -0.5 -0.3 -0.4 -0.1 -0.0 -0.1 -0.2 -0.4 -0.0 0.2 -0.1 -0.2 0.0 -0.4 0.1 -0.3 -0.3 -0.1 -0.4 -0.1 -0.4 -0.3 0.8 -0.3 -0.4 0.5 -0.3
Ulcerative Colitis (UC) 0.3 0.5 2.1 0.5 0.8 1.4 0.8 0.8 0.7 0.7 0.8 0.5 0.5 0.7 0.7 0.8 0.6 0.7 0.8 0.3 0.8 0.7 0.9 0.8 0.7 0.8 0.6 0.5 1.0 0.7 0.7 0.7 0.5 0.9 0.6 0.6 0.6 0.4 0.7 0.5 0.6 0.8 0.5 -1.0 1.2 0.7
Major Depression (MDD) 0.1 0.1 0.5 0.2 0.1 0.7 0.1 0.0 0.1 0.2 0.2 0.4 0.0 0.2 0.2 -0.1 0.1 0.2 0.3 0.3 0.2 0.3 0.1 0.2 0.0 0.1 0.3 0.3 0.3 0.3 0.2 0.5 0.1 0.2 0.2 0.2 0.3 0.4 0.2 0.2 0.1 0.2 0.1 0.4 0.2 0.1
Reaction Time 0.0 0.1 0.5 -0.1 -0.2 0.1 -0.2 -0.3 -0.3 -0.4 -0.3 -0.4 -0.3 -0.3 -0.4 -0.3 -0.0 -0.1 -0.4 0.0 -0.3 -0.2 -0.2 -0.4 -0.3 -0.2 -0.4 0.0 -0.1 -0.2 -0.1 -0.3 -0.3 -0.0 -0.5 -0.2 -0.2 -0.7 -0.4 0.0 -0.2 -0.5 -0.2 0.0 -0.5 -0.3
Verbal and Numeric Reasoning (VNR) 1.7 4.1 6.0 2.4 2.0 2.1 2.0 2.3 2.1 2.2 2.2 2.3 2.1 2.4 2.2 2.3 1.6 1.8 1.4 1.7 1.9 2.2 2.0 2.1 2.0 2.0 2.0 1.5 2.1 2.0 1.9 2.3 2.0 2.1 2.0 1.8 1.9 2.0 2.2 1.6 1.9 2.0 1.8 -1.7 2.3 2.0
Breast Cancer 0.0 0.1 1.2 0.1 0.0 -1.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.5 0.1 -0.2 0.1 0.0 0.2 0.4 -0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 -0.0 0.2 -0.1 0.1 0.0 -1.1 -0.0 0.3 -0.1 0.1
Ovarian Cancer 1.6 2.2 3.5 0.9 1.5 1.9 1.4 1.5 1.6 1.5 1.6 1.4 1.5 1.5 1.5 1.6 1.2 1.2 1.1 1.9 1.5 1.3 1.5 1.7 1.6 1.6 1.5 0.8 1.6 1.3 1.7 1.0 1.3 1.8 1.6 1.8 1.2 1.2 1.7 1.5 1.7 0.9 1.4 -1.4 1.5 1.5
Prostate Cancer 0.0 0.1 0.4 0.4 0.2 0.6 0.3 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.3 0.4 0.3 0.2 0.2 0.2 0.2 0.4 0.1 0.2 0.2 0.2 -0.0 0.4 0.2 0.2 0.3 0.2 0.1 0.2 0.5 0.1 0.0 0.1 0.2 -0.2 0.2 -0.2 0.0 0.3
Age at First Birth 3.9 5.6 7.4 -2.3 -2.4 -2.3 -2.4 -2.4 -2.5 -2.5 -2.5 -2.3 -2.4 -2.4 -2.5 -2.6 -2.1 -2.3 -2.5 -2.4 -2.3 -2.4 -2.4 -2.5 -2.1 -2.4 -2.4 -2.1 -2.5 -2.4 -2.5 -2.2 -2.2 -2.7 -2.3 -2.5 -2.4 -2.0 -2.5 -2.4 -2.5 -2.2 -2.4 1.9 -2.4 -2.4
Bipolar Disorder (2011) 0.0 0.0 0.2 0.3 0.2 0.3 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.2 -0.1 -0.1 0.1 0.2 0.4 0.2 -0.2 -0.3 0.2 0.2 0.0 0.0 0.2 0.1 -0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 -0.5 0.1 0.2 -0.2 0.3
Body Mass Index (BMI) (2010) 0.2 0.3 0.9 0.4 0.7 0.1 0.5 0.5 0.5 0.4 0.5 0.5 0.6 0.3 0.4 0.5 0.9 0.7 0.6 0.3 0.6 0.6 0.7 0.3 0.5 0.6 0.5 0.8 0.2 0.7 0.5 0.5 0.9 0.5 0.7 0.5 0.4 0.5 0.5 0.8 0.6 0.8 0.7 -0.9 0.1 0.6
Coronary Artery Disease (CAD) 0.1 0.1 0.9 -0.3 -0.3 0.3 -0.3 -0.3 -0.2 0.1 -0.1 0.1 -0.3 -0.0 0.0 -0.2 -0.3 -0.1 -0.3 0.3 -0.4 -0.2 -0.3 -0.1 -0.3 -0.3 -0.0 -0.3 -0.1 -0.4 -0.2 -0.2 -0.2 0.3 -0.3 -0.1 -0.3 -0.0 0.0 -0.2 -0.1 -0.5 -0.2 1.0 -0.2 -0.2
Crohns Disease (2012) 0.2 0.3 1.3 0.8 0.4 1.1 0.5 0.6 0.7 0.2 0.4 0.0 0.4 0.4 0.2 0.5 0.2 0.3 0.7 0.4 0.5 0.3 0.5 0.4 0.6 0.5 0.3 1.1 0.7 0.7 0.6 0.7 0.3 0.6 0.4 0.4 0.7 0.4 0.4 0.3 0.5 1.1 0.5 -1.0 0.8 0.3
Mean Putamen Volume 0.3 0.3 1.4 -0.6 -0.5 -0.1 -0.5 -0.6 -0.4 -0.5 -0.5 -0.6 -0.5 -0.5 -0.5 -0.5 -0.7 -0.7 -0.8 -0.8 -0.5 -0.8 -0.6 -0.4 -0.4 -0.5 -0.7 -0.8 -0.4 -0.6 -0.6 -0.4 -0.5 -1.2 -0.5 -0.6 -0.6 -0.7 -0.4 -0.5 -0.6 0.2 -0.6 0.2 -0.5 -0.6
Fasting Glucose 2.0 2.3 3.9 1.8 1.5 1.1 1.6 1.8 1.5 1.3 1.5 1.2 1.6 1.3 1.3 1.8 1.2 1.2 1.4 1.7 1.5 1.4 1.6 1.4 1.6 1.6 1.4 1.7 1.7 1.6 1.6 1.5 1.6 1.7 1.6 1.7 1.2 1.1 1.4 1.6 1.7 1.7 1.7 -2.0 1.4 1.5
HbA1C 0.2 0.2 1.8 -0.5 -0.1 -0.6 -0.1 -0.0 -0.2 -0.4 -0.2 -0.9 0.1 -0.2 -0.4 0.1 -0.1 -0.4 -0.1 -0.3 -0.0 -0.6 -0.0 0.2 0.2 -0.1 -0.4 -0.2 0.4 -0.0 -0.0 0.6 -0.2 -0.8 -0.2 -0.2 -0.4 -0.3 -0.1 -0.3 -0.2 1.4 -0.1 -1.2 0.4 -0.3
HDL Cholesterol 3.2 5.3 7.5 -2.3 -2.4 -1.7 -2.4 -2.5 -2.4 -2.3 -2.4 -2.6 -2.4 -2.2 -2.3 -2.6 -2.3 -2.3 -2.4 -2.0 -2.3 -2.6 -2.4 -1.7 -1.9 -2.4 -2.5 -2.6 -2.2 -2.5 -2.2 -1.9 -2.7 -2.6 -2.5 -2.3 -2.1 -2.1 -2.3 -2.3 -2.4 -1.5 -2.5 2.1 -1.6 -2.6
LDL Cholesterol 0.4 0.6 4.3 0.5 0.7 1.0 0.7 0.5 0.6 0.9 0.8 0.5 0.7 0.8 0.9 0.6 0.3 0.7 1.0 0.1 0.8 0.3 0.7 0.8 0.9 0.7 0.5 0.6 1.1 0.8 0.6 1.3 0.4 -0.2 0.5 0.5 0.6 0.7 1.0 0.7 0.6 2.1 0.6 -0.9 1.0 0.6
Lupus 0.6 0.9 1.8 1.1 0.9 0.8 0.9 0.9 1.0 1.1 1.0 1.0 0.9 1.0 1.1 0.9 0.8 1.0 1.0 0.6 0.9 0.9 0.9 0.9 1.1 0.9 0.9 1.2 1.2 0.9 0.9 1.1 0.9 0.8 1.0 0.8 1.1 1.2 1.0 0.9 0.8 1.3 1.0 -0.7 1.1 0.9
Neuroticism (2016) 0.1 0.1 0.7 -0.2 0.1 -0.8 -0.0 0.1 0.1 -0.3 -0.2 -0.2 0.2 -0.4 -0.3 0.0 0.4 0.0 -0.0 -0.0 0.1 0.1 0.1 -0.5 -0.6 0.1 -0.0 -0.3 -0.2 0.1 0.1 -0.5 0.2 -0.1 -0.0 0.1 -0.0 -0.2 -0.3 0.2 0.1 -0.8 0.3 -0.1 -0.8 0.1
Primary Biliary Cirrhosis 1.1 1.6 2.4 -1.4 -1.2 -0.8 -1.3 -1.4 -1.3 -1.1 -1.2 -1.3 -1.2 -1.2 -1.1 -1.4 -1.2 -1.1 -1.3 -1.5 -1.3 -1.2 -1.2 -1.3 -1.2 -1.3 -1.2 -1.5 -1.1 -1.3 -1.2 -1.1 -1.4 -1.5 -1.3 -1.3 -1.4 -1.0 -1.1 -1.4 -1.3 -1.1 -1.2 1.2 -1.5 -1.3
Rheumatoid Arthritis 0.1 0.2 0.6 -0.6 -0.4 -0.2 -0.3 -0.4 -0.4 -0.8 -0.5 -0.6 -0.5 -0.7 -0.8 -0.4 -0.5 -0.3 -0.5 -0.1 -0.4 -0.7 -0.5 -0.3 0.0 -0.4 -0.6 -0.0 -0.4 -0.3 -0.3 -0.5 -0.2 -0.4 -0.3 -0.2 -0.3 -0.5 -0.6 -0.4 -0.2 0.4 -0.2 -0.5 -0.2 -0.4
Schizophrenia (2014) 0.1 0.1 0.3 0.2 0.3 -0.4 0.3 0.3 0.1 0.4 0.4 0.4 0.4 0.3 0.4 0.3 0.4 0.2 0.4 0.4 0.2 0.4 0.2 0.3 0.2 0.3 0.4 0.5 0.4 0.4 0.3 0.3 0.4 0.5 0.4 0.4 0.4 0.1 0.4 0.4 0.4 0.3 0.5 0.0 0.2 0.4
Triglycerides 0.8 1.3 2.1 1.0 1.1 0.7 1.1 1.1 1.0 1.0 1.1 1.0 1.1 1.1 1.0 1.2 1.2 1.1 1.4 0.9 1.1 1.1 1.2 1.0 1.1 1.1 1.1 1.5 1.3 1.3 1.1 1.4 1.1 1.1 1.1 1.0 1.3 1.1 1.1 1.1 1.1 1.1 1.2 -1.3 1.2 1.1
Type 2 Diabetes (T2D) (2012) 0.3 0.4 0.9 0.9 0.5 0.7 0.5 0.7 0.6 0.7 0.7 0.9 0.5 0.6 0.7 0.6 0.3 0.3 0.7 0.3 0.4 0.6 0.5 0.4 0.2 0.6 0.7 0.4 0.3 0.5 0.3 0.3 0.8 0.9 0.8 0.5 0.7 0.9 0.8 0.3 0.5 0.8 0.7 -0.1 0.6 0.7
Ulcerative Colitis 0.6 0.8 2.6 0.7 0.9 1.4 0.9 0.9 0.9 1.2 1.0 1.0 0.7 1.0 1.2 1.0 0.5 0.8 0.9 0.1 0.9 0.9 1.0 0.8 0.9 0.9 0.9 0.8 1.3 0.9 0.8 0.9 0.5 0.9 0.8 0.6 0.8 0.6 1.1 0.6 0.7 1.6 0.6 -0.6 1.2 0.9
Blood Eosinophil Count 3.3 25.6 34.3 5.1 5.1 4.6 5.0 5.2 4.9 4.6 4.9 4.6 5.0 4.6 4.5 5.2 5.1 5.0 5.2 5.9 5.0 4.8 5.1 5.2 5.1 5.1 5.1 5.4 5.5 5.0 5.5 5.3 4.9 5.7 5.0 5.6 5.0 5.1 4.7 5.3 5.5 3.8 5.1 -5.0 4.7 5.0
Blood Platelet Count 0.9 10.2 19.0 -3.5 -3.0 -2.0 -3.1 -3.1 -3.1 -3.8 -3.3 -4.4 -3.2 -3.5 -3.8 -3.3 -3.0 -3.2 -3.4 -3.0 -3.1 -3.8 -3.0 -2.8 -2.7 -3.0 -3.7 -3.5 -2.8 -3.2 -3.0 -2.8 -3.4 -3.6 -3.2 -3.1 -3.1 -3.6 -3.4 -3.2 -3.1 -1.5 -3.2 0.8 -3.0 -3.4
Blood Red Count 1.8 17.6 24.1 4.4 4.2 4.4 4.3 4.6 4.4 4.4 4.4 4.9 4.1 4.3 4.4 4.4 4.0 3.9 4.1 3.4 4.1 4.6 4.3 3.9 3.3 4.3 4.6 3.7 3.9 4.1 3.8 3.9 4.9 4.7 4.4 4.0 4.2 4.7 4.6 3.8 4.1 3.1 4.3 -2.9 4.1 4.5
Blood White Count 0.0 0.1 0.9 -0.3 0.1 -0.7 0.0 -0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.3 0.1 0.0 -0.5 0.1 0.4 0.1 -0.6 -0.9 0.1 0.2 -0.2 -0.1 -0.0 -0.2 -0.1 0.1 0.2 0.1 -0.2 -0.3 0.1 0.2 -0.1 -0.2 -1.0 -0.2 0.7 -0.9 0.2
Heel T-Score 0.4 3.2 8.1 -2.1 -1.8 -0.8 -1.8 -1.9 -2.1 -1.2 -1.6 -1.0 -2.0 -1.4 -1.3 -2.0 -2.0 -1.5 -1.3 -1.5 -1.8 -1.7 -1.8 -1.6 -1.4 -1.9 -1.7 -1.7 -2.1 -2.1 -1.8 -2.5 -1.8 -1.8 -1.4 -1.7 -1.6 -1.7 -1.6 -1.9 -1.8 -2.5 -1.7 2.8 -1.2 -1.8
BMI 0.2 1.3 3.3 0.9 1.2 1.8 1.1 0.9 1.1 0.5 0.9 0.7 1.1 0.6 0.6 0.9 1.6 1.4 1.3 1.4 1.3 1.2 1.2 0.8 0.9 1.2 1.2 1.2 0.7 1.2 1.3 1.1 1.1 1.3 1.0 1.4 1.1 1.1 0.7 1.7 1.4 -0.2 1.1 -1.8 0.2 1.2
Height 0.0 0.2 1.0 1.0 0.1 -0.5 0.3 0.6 0.0 0.8 0.4 0.8 0.4 0.6 0.8 0.0 -0.2 -0.0 -0.1 -0.6 -0.0 0.5 -0.0 -0.2 0.3 0.1 0.3 -0.2 0.1 0.1 -0.2 -0.2 0.7 0.4 0.3 -0.2 -0.2 0.3 0.5 -0.2 -0.1 0.7 0.1 0.6 0.1 0.3
Waist Hip Ratio (WHR) 0.0 0.1 0.9 0.4 0.1 1.0 0.1 0.4 -0.0 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.2 0.3 -0.0 0.1 -0.1 0.3 0.2 0.0 -0.1 0.2 0.2 -0.1 0.2 0.2 0.1 0.2 0.6 0.7 0.2 0.1 0.3 0.2 0.1 -0.1 0.1 -0.0 0.2 -0.1 0.3 0.2
Systolic Blood Pressure 0.7 3.6 8.3 -2.0 -1.8 -2.0 -1.7 -1.6 -1.9 -2.0 -1.8 -1.7 -1.7 -2.0 -2.0 -1.9 -1.7 -1.8 -1.9 -2.4 -1.8 -1.5 -1.8 -2.3 -2.4 -1.8 -1.6 -1.8 -2.0 -1.8 -2.0 -2.1 -1.5 -1.7 -1.7 -2.0 -1.6 -1.4 -1.9 -2.2 -1.9 -2.9 -1.8 1.5 -2.4 -1.6
Smoking Status 0.0 0.0 0.4 -0.2 0.0 -0.1 0.1 0.2 -0.2 -0.1 0.0 -0.1 0.0 -0.0 -0.1 0.1 -0.1 -0.2 -0.2 -0.3 0.2 -0.1 0.0 0.1 0.2 0.1 -0.1 -0.2 0.0 -0.0 -0.1 0.0 0.1 -0.4 0.2 -0.2 -0.4 -0.3 -0.0 -0.2 -0.1 0.1 -0.1 -0.7 0.0 0.0
Allergy or Eczema 0.1 0.3 2.1 -0.3 0.4 1.4 0.3 0.4 0.3 0.1 0.3 0.5 0.2 0.1 0.0 0.6 0.6 0.1 0.1 1.4 0.4 0.4 0.4 0.8 0.3 0.5 0.6 0.1 0.1 0.2 0.7 0.1 0.6 1.1 0.4 1.0 0.4 0.4 0.3 0.9 0.9 -1.0 0.5 -0.6 -0.1 0.5
Cardiovascular Disease 0.7 2.2 8.9 -1.6 -1.3 -1.2 -1.2 -1.1 -1.5 -1.5 -1.4 -1.2 -1.2 -1.3 -1.4 -1.4 -1.3 -1.1 -1.6 -2.0 -1.1 -1.0 -1.2 -1.7 -1.9 -1.2 -1.3 -1.9 -1.7 -1.3 -1.5 -1.6 -1.3 -1.6 -1.3 -1.6 -1.2 -1.5 -1.5 -1.7 -1.5 -3.0 -1.4 1.0 -2.2 -1.2
Hypothyroidism (self reported) 3.1 7.1 11.3 -2.0 -2.7 -1.8 -2.6 -2.6 -2.6 -2.2 -2.5 -1.9 -2.7 -2.3 -2.2 -2.6 -2.9 -2.5 -2.9 -3.2 -2.6 -2.2 -2.7 -2.9 -2.8 -2.7 -2.5 -3.0 -3.1 -2.9 -3.1 -3.2 -2.5 -2.9 -2.5 -3.0 -2.5 -2.2 -2.5 -3.0 -3.0 -3.0 -2.7 3.4 -2.3 -2.5
Respiratory disease 0.1 0.3 1.8 -0.1 0.5 1.3 0.4 0.4 0.3 0.4 0.4 0.4 0.3 0.3 0.4 0.5 0.5 0.5 0.3 1.0 0.5 0.3 0.5 0.6 0.5 0.5 0.4 0.2 0.5 0.4 0.8 0.4 0.4 0.8 0.3 0.9 -0.0 0.1 0.4 0.9 0.7 0.1 0.6 -0.5 -0.3 0.4
Type 2 Diabetes (T2D) (2018) 3.7 7.0 8.8 2.3 2.8 2.9 2.8 2.6 2.5 2.5 2.6 2.4 2.5 2.5 2.5 2.7 3.0 3.0 2.9 2.5 2.6 2.7 2.8 2.5 2.8 2.7 2.7 2.5 2.7 2.6 2.8 2.7 2.8 2.7 2.4 2.7 2.6 2.5 2.5 2.9 2.6 1.9 2.9 -2.6 2.5 2.6
Lung FEV1/FVC ratio 0.6 3.2 8.8 1.6 1.8 3.0 1.8 1.7 1.7 1.5 1.8 1.9 1.6 1.4 1.5 1.8 1.8 2.0 1.5 1.8 1.7 1.9 1.9 1.5 1.5 1.9 2.0 1.6 1.6 1.6 1.8 1.2 2.0 2.5 1.6 2.0 2.3 1.9 1.7 1.9 2.0 0.8 2.0 -1.8 1.3 2.0
Lung FVC 0.0 0.1 0.7 0.2 0.0 -0.7 0.2 0.0 0.1 0.3 0.2 0.1 0.2 0.3 0.3 0.2 -0.3 -0.4 0.1 -0.2 0.2 0.3 0.0 -0.1 -0.1 0.0 0.1 -0.5 0.2 -0.2 -0.0 -0.1 -0.1 -0.5 0.1 -0.1 -0.8 -0.1 0.1 -0.1 -0.1 -0.4 -0.0 0.3 -0.1 0.1
Neuroticism 0.5 1.3 3.5 -1.2 -1.0 -1.9 -1.1 -1.0 -1.0 -1.0 -1.0 -1.0 -0.9 -1.0 -1.0 -1.0 -0.9 -1.0 -1.2 -0.9 -1.0 -1.1 -1.0 -1.3 -1.4 -1.0 -1.0 -1.4 -1.1 -1.0 -1.0 -1.2 -1.1 -1.2 -1.0 -0.9 -1.4 -1.0 -1.0 -1.0 -1.0 -1.3 -1.1 1.1 -1.7 -1.0
Chronotype (morning person) 0.4 0.9 1.6 0.6 1.0 0.5 1.0 0.9 0.9 0.8 0.9 0.6 1.0 0.7 0.8 0.9 1.0 1.1 1.1 0.9 1.0 1.0 1.0 0.9 1.3 1.0 0.9 1.2 1.0 1.1 1.1 0.8 0.8 0.8 0.9 1.1 1.1 0.7 0.8 0.9 1.0 0.7 0.8 -1.2 0.8 0.9
Hair Pigment 0.1 1.8 5.6 -1.3 -1.4 -0.8 -1.4 -1.5 -1.2 -1.0 -1.2 -1.1 -1.4 -1.1 -1.0 -1.3 -1.8 -1.4 -1.2 -1.7 -1.1 -1.6 -1.4 -1.2 -1.2 -1.4 -1.4 -1.1 -1.3 -1.2 -1.6 -1.1 -1.5 -2.4 -1.2 -1.5 -1.6 -1.2 -1.0 -1.5 -1.5 0.1 -1.5 1.3 -0.9 -1.4
Tanning 0.1 0.7 2.3 0.7 0.8 0.9 0.9 1.1 0.6 0.6 0.8 0.5 0.9 0.7 0.6 1.0 0.6 0.7 1.1 0.6 0.8 0.8 0.8 0.6 0.9 0.8 0.7 0.6 1.0 0.8 0.8 0.8 1.2 0.4 0.8 0.7 0.3 0.6 0.7 0.5 0.8 0.9 1.0 -1.5 0.8 0.8
Hand grip strength (left) 0.1 0.3 1.5 -0.3 -0.4 0.6 -0.3 -0.2 -0.6 -0.3 -0.3 -0.4 -0.3 -0.3 -0.3 -0.5 -0.6 -0.6 -0.1 -0.9 -0.3 -0.3 -0.4 -0.3 0.2 -0.4 -0.4 -1.1 -0.4 -0.5 -0.5 -0.7 -0.3 -1.2 -0.4 -0.6 -0.9 -0.2 -0.2 -0.7 -0.5 0.1 -0.4 0.1 0.6 -0.4
Number of treatments/medications taken 1.0 1.7 3.5 -1.3 -1.3 -1.8 -1.3 -1.2 -1.3 -1.1 -1.2 -1.2 -1.2 -1.2 -1.1 -1.1 -1.0 -1.3 -1.3 -1.0 -1.3 -1.2 -1.3 -1.4 -1.6 -1.2 -1.3 -1.2 -1.2 -1.2 -1.2 -1.3 -1.4 -1.3 -1.3 -1.2 -1.6 -1.7 -1.3 -1.1 -1.2 -1.9 -1.3 1.5 -1.8 -1.3
Average weekly spirits intake 0.8 1.0 1.7 -1.0 -1.0 -0.8 -1.1 -1.3 -1.1 -0.9 -1.1 -1.0 -1.2 -0.9 -0.9 -1.2 -0.9 -0.8 -0.9 -1.2 -1.1 -1.1 -1.0 -1.0 -0.7 -1.1 -1.1 -0.9 -1.0 -1.1 -1.2 -0.8 -1.2 -1.2 -1.1 -1.2 -0.7 -0.6 -0.9 -1.0 -1.2 -0.1 -1.2 1.0 -0.5 -1.2
Sensitivity / hurt feelings 0.2 0.4 1.3 0.1 0.7 0.0 0.5 0.8 0.7 0.3 0.6 0.4 0.6 0.3 0.3 0.8 0.9 0.5 0.6 0.7 0.6 0.6 0.7 0.6 0.5 0.7 0.7 0.7 0.8 0.6 0.7 0.7 0.7 0.7 0.8 0.8 0.7 0.9 0.6 0.5 0.8 0.7 0.7 -1.2 0.6 0.7
Frequency of depressed mood in last 2 weeks 5.0 7.0 9.1 -2.8 -2.7 -2.7 -2.7 -2.6 -2.6 -2.5 -2.6 -2.6 -2.7 -2.5 -2.5 -2.8 -2.5 -2.4 -3.0 -2.4 -2.8 -2.8 -2.7 -2.4 -2.7 -2.7 -2.7 -2.8 -2.6 -2.7 -2.6 -2.5 -2.7 -2.5 -2.6 -2.6 -2.3 -2.4 -2.6 -2.6 -2.7 -2.4 -2.7 2.6 -2.8 -2.8
Hearing difficulty/problems: Yes 0.5 0.7 1.3 0.7 0.8 0.4 0.9 1.0 0.8 0.9 0.9 1.1 0.8 0.9 0.9 0.9 0.7 0.9 0.8 0.6 0.8 1.0 0.9 0.8 0.7 0.9 0.9 1.1 0.9 0.9 0.8 0.5 0.9 1.0 1.0 0.8 1.1 0.5 0.8 0.6 0.8 -0.0 0.9 -0.6 0.7 1.0
Relative age of first facial hair 0.1 0.3 1.4 -0.8 -0.5 -0.1 -0.4 -0.4 -0.7 -0.4 -0.5 -0.6 -0.5 -0.4 -0.5 -0.7 -0.4 -0.1 -0.1 -0.4 -0.4 -0.8 -0.4 -0.4 -0.1 -0.5 -0.7 -0.6 -0.4 -0.3 -0.4 -0.1 -0.5 -1.2 -0.6 -0.5 -0.7 -0.7 -0.5 -0.4 -0.5 0.1 -0.3 -0.0 -0.4 -0.7
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.5 -0.6 -0.6 -0.4 -0.7 -0.7 -0.7 -0.7 -0.7 -0.7 -0.6 -0.7 -0.7 -0.7 -0.3 -0.6 -0.9 -0.3 -0.7 -0.7 -0.7 -0.7 -0.8 -0.7 -0.7 -0.9 -0.8 -0.8 -0.5 -0.8 -0.8 -0.7 -0.8 -0.5 -0.7 -0.7 -0.8 -0.5 -0.6 -1.1 -0.8 0.8 -1.2 -0.7
Ever used hormone-replacement therapy (HRT) 0.2 0.2 1.2 -0.5 -0.3 -0.7 -0.5 -0.5 -0.4 -0.6 -0.5 -1.1 -0.4 -0.5 -0.6 -0.1 -0.1 -0.5 -0.2 0.4 -0.6 -0.9 -0.4 -0.2 -0.1 -0.4 -0.7 0.0 -0.2 -0.3 -0.1 -0.2 -0.7 -0.4 -0.5 -0.1 -0.6 -1.0 -0.5 0.1 -0.2 -0.0 -0.4 -0.3 -0.3 -0.7
Ever had hysterectomy (womb removed) 1.2 1.4 2.9 0.9 1.2 1.7 1.1 1.1 1.1 1.2 1.2 1.0 1.0 1.2 1.2 1.2 1.3 1.6 1.3 1.4 1.1 0.9 1.2 1.1 1.1 1.1 1.1 0.9 1.3 1.0 1.3 1.2 1.1 1.1 1.0 1.3 1.3 1.3 1.2 1.2 1.2 0.5 1.4 -0.9 1.2 1.0
Systolic blood pressure, automated reading 0.3 0.8 5.3 -0.9 -0.7 -0.8 -0.7 -0.7 -0.8 -1.2 -1.0 -1.1 -0.8 -1.1 -1.2 -0.8 -0.3 -0.7 -0.9 -0.5 -0.8 -0.6 -0.7 -1.1 -1.2 -0.7 -0.7 -0.5 -1.0 -0.8 -0.6 -1.0 -0.6 -0.3 -0.9 -0.6 -0.9 -0.7 -1.2 -0.6 -0.7 -2.3 -0.6 0.4 -1.5 -0.8
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 2.6 0.6 0.8 0.5 0.7 0.7 0.6 0.7 0.7 0.9 0.6 0.7 0.8 0.9 0.9 0.8 0.6 1.1 0.6 1.0 0.7 0.6 0.5 0.8 0.9 0.6 0.7 0.6 0.8 0.6 1.1 1.6 0.6 0.9 0.6 0.4 0.6 0.9 0.8 -0.3 1.0 -0.1 0.1 0.7
Angina 0.7 1.0 1.9 0.9 1.1 0.7 1.0 1.0 1.0 0.8 0.9 0.8 1.0 0.8 0.8 1.0 1.1 1.0 1.1 1.1 1.1 0.9 1.0 1.1 1.0 1.0 1.0 1.0 1.1 1.1 1.1 1.0 1.0 0.9 1.0 1.1 0.8 0.8 0.8 1.0 1.1 0.4 0.9 -1.4 0.9 1.1
Medication for hormone replacement therapy 0.2 0.3 0.7 -0.4 -0.5 -0.3 -0.6 -0.6 -0.5 -0.3 -0.4 -0.6 -0.5 -0.3 -0.3 -0.5 -0.5 -0.7 -0.7 -0.5 -0.5 -0.6 -0.6 -0.6 -0.4 -0.5 -0.6 -0.4 -0.3 -0.5 -0.5 -0.2 -0.7 -0.5 -0.6 -0.6 -0.9 -0.5 -0.2 -0.4 -0.6 0.1 -0.7 0.7 -0.7 -0.6
Vitamin and mineral supplements 0.4 0.5 1.1 -0.8 -0.6 -0.1 -0.7 -0.8 -0.8 -0.8 -0.8 -0.8 -0.7 -0.8 -0.8 -0.8 -0.6 -0.8 -0.4 -0.9 -0.6 -0.4 -0.6 -0.8 -1.0 -0.7 -0.7 -0.9 -0.8 -0.7 -0.8 -0.5 -0.8 -0.7 -0.8 -0.8 -0.6 -0.9 -0.8 -0.6 -0.8 -0.2 -0.9 0.5 -1.0 -0.7
Supplements: Zinc 2.4 2.6 4.1 -1.4 -1.6 -1.7 -1.6 -1.6 -1.5 -1.5 -1.6 -1.4 -1.6 -1.5 -1.5 -1.4 -1.5 -1.5 -1.9 -1.7 -1.6 -1.4 -1.6 -1.9 -1.8 -1.6 -1.6 -1.7 -1.6 -1.7 -1.7 -1.6 -1.6 -1.5 -1.7 -1.7 -1.5 -1.2 -1.6 -1.7 -1.6 -2.0 -1.7 1.8 -1.8 -1.5
Medication: Co-codamol 1.2 1.4 3.2 -1.3 -1.1 -1.2 -1.3 -1.4 -1.3 -1.0 -1.2 -1.1 -1.2 -1.1 -1.0 -1.3 -0.7 -1.0 -1.2 -0.6 -1.2 -1.0 -1.2 -1.1 -1.4 -1.1 -1.0 -1.0 -1.1 -1.2 -0.9 -1.1 -1.6 -0.7 -1.3 -0.9 -1.2 -1.0 -1.1 -0.6 -1.0 -1.8 -1.3 1.5 -1.8 -1.2
Medication: Metformin 1.0 1.3 2.1 1.0 1.2 1.4 1.1 1.0 1.1 1.1 1.1 1.0 1.0 1.1 1.1 1.0 1.3 1.4 1.4 1.3 1.0 1.0 1.1 1.2 1.1 1.1 1.2 1.0 1.1 1.1 1.1 1.4 1.2 1.4 1.0 1.2 1.2 1.2 1.1 1.4 1.2 1.1 1.4 -1.1 1.0 1.1
Diabetes (father) 0.0 0.0 0.5 0.0 -0.1 0.3 -0.1 0.1 -0.1 0.0 -0.0 -0.1 -0.1 -0.0 0.0 -0.2 -0.0 -0.0 0.2 -0.3 -0.1 0.0 -0.1 -0.2 0.1 -0.1 -0.1 -0.2 -0.4 -0.1 -0.1 -0.4 -0.1 0.0 0.0 -0.1 0.2 -0.1 -0.1 -0.2 -0.1 -0.7 0.0 0.2 -0.0 -0.1
Diabetes (mother) 0.6 0.8 1.6 -0.9 -0.9 -0.5 -0.9 -0.9 -0.8 -0.9 -0.9 -1.1 -1.0 -0.8 -0.9 -1.1 -1.0 -0.7 -0.8 -1.2 -1.0 -1.1 -0.9 -0.9 -0.3 -1.0 -1.1 -0.6 -0.9 -0.8 -0.9 -0.6 -0.8 -1.2 -1.0 -1.1 -0.9 -0.9 -0.8 -1.0 -1.0 0.6 -0.9 0.3 -0.5 -1.1
Severe depression (siblings) 0.3 0.4 0.9 0.5 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.6 0.7 0.5 0.5 0.5 0.5 0.5 0.5 0.3 0.6 0.5 0.5 0.6 0.5 0.6 0.6 0.7 0.6 0.6 0.4 0.5 0.8 0.4 0.9 0.5 0.8 0.6 0.7 0.4 0.5 0.9 0.6 -0.7 0.4 0.7
Pack years adult smoking proportion 0.0 0.1 0.3 -0.0 -0.1 -0.4 -0.2 -0.1 -0.1 -0.5 -0.3 -0.5 -0.1 -0.4 -0.4 -0.2 0.1 -0.2 -0.2 0.4 -0.1 -0.2 -0.1 -0.3 -0.4 -0.1 -0.2 0.1 -0.1 0.1 0.1 0.1 -0.1 0.3 -0.2 0.1 -0.3 -0.6 -0.4 0.2 0.1 -0.2 -0.2 -0.2 -0.6 -0.1
Impedance of leg (right) 1.7 8.0 10.8 -2.5 -3.1 -1.6 -3.0 -2.7 -3.0 -2.8 -2.9 -2.5 -3.2 -2.8 -2.8 -2.9 -3.1 -3.1 -2.6 -3.3 -3.0 -2.8 -2.9 -2.7 -2.6 -3.1 -2.9 -2.7 -3.1 -3.0 -3.2 -3.0 -2.6 -2.7 -3.1 -3.1 -2.3 -2.3 -2.8 -3.3 -3.1 -2.2 -2.7 3.0 -1.9 -2.9
Leg fat-free mass (left) 1.9 10.3 13.0 3.3 3.5 2.6 3.4 3.3 3.4 3.2 3.3 3.1 3.5 3.1 3.2 3.0 3.4 3.3 3.2 3.2 3.4 3.5 3.3 2.8 3.0 3.4 3.5 2.8 3.1 3.3 3.4 2.9 3.4 3.4 3.4 3.4 2.8 3.1 3.2 3.6 3.4 2.2 3.2 -3.1 2.3 3.4
Trunk fat percentage 1.2 4.6 12.0 2.1 2.2 3.5 2.1 2.2 2.0 1.4 1.8 1.8 1.9 1.4 1.4 1.8 2.7 2.2 2.5 2.2 2.1 2.2 2.2 1.8 1.9 2.2 2.2 2.4 1.6 2.2 2.3 1.8 2.5 2.7 2.0 2.4 2.6 2.3 1.6 2.5 2.3 0.5 2.4 -2.8 1.6 2.1
Hand grip strength (right) 0.5 1.3 2.9 -1.1 -1.1 -0.4 -1.1 -1.1 -1.3 -1.1 -1.1 -1.1 -1.1 -1.2 -1.1 -1.4 -1.1 -1.3 -0.9 -1.5 -1.0 -0.9 -1.1 -1.0 -0.7 -1.1 -1.1 -1.7 -1.2 -1.3 -1.4 -1.5 -1.1 -1.6 -1.1 -1.3 -1.3 -0.9 -1.0 -1.3 -1.2 -0.4 -1.3 0.8 -0.3 -1.1
Townsend deprivation index at recruitment 1.5 2.1 3.8 -1.8 -1.4 -1.8 -1.5 -1.4 -1.4 -1.6 -1.5 -1.8 -1.3 -1.6 -1.6 -1.4 -1.3 -1.5 -1.6 -1.1 -1.3 -1.5 -1.5 -1.3 -1.6 -1.4 -1.4 -1.4 -1.2 -1.4 -1.3 -1.2 -1.7 -1.3 -1.4 -1.3 -1.9 -1.8 -1.5 -1.2 -1.3 -0.9 -1.6 0.8 -1.9 -1.5
Current tobacco smoking 2.1 3.4 5.2 -1.9 -1.8 -1.9 -1.8 -1.9 -1.9 -1.8 -1.8 -1.8 -1.9 -1.8 -1.7 -1.7 -2.0 -2.0 -1.9 -2.0 -1.8 -1.9 -1.9 -1.7 -1.7 -1.8 -2.0 -1.7 -1.8 -1.8 -2.0 -1.5 -1.7 -2.2 -1.7 -1.9 -2.3 -2.0 -1.8 -1.7 -1.9 -1.1 -1.8 1.4 -1.9 -1.9
Average weekly fortified wine intake 0.2 0.3 0.8 -0.3 -0.5 0.4 -0.5 -0.4 -0.5 -0.6 -0.6 -0.5 -0.6 -0.5 -0.6 -0.5 -0.5 -0.5 -0.7 -0.4 -0.5 -0.6 -0.5 -0.4 -0.4 -0.5 -0.6 -0.4 -0.6 -0.7 -0.4 -0.8 -0.4 -0.1 -0.6 -0.5 -0.4 -0.8 -0.6 -0.5 -0.5 -0.9 -0.4 0.4 -0.7 -0.5
Maternal smoking around birth 0.4 0.6 1.2 -0.7 -0.9 -0.6 -0.8 -0.8 -0.8 -1.0 -0.9 -0.9 -0.8 -0.9 -1.1 -0.8 -1.0 -0.9 -0.8 -0.6 -0.8 -0.9 -0.8 -0.6 -0.9 -0.8 -0.8 -0.6 -0.5 -0.6 -0.8 -0.5 -0.6 -0.5 -0.7 -0.7 -1.0 -0.9 -0.8 -1.0 -0.7 0.1 -0.7 0.1 -0.6 -0.8
Fed-up feelings 0.1 0.2 0.7 -0.5 -0.3 -0.6 -0.4 -0.4 -0.3 -0.3 -0.3 -0.5 -0.3 -0.3 -0.3 -0.4 -0.3 -0.3 -0.3 -0.5 -0.2 -0.4 -0.3 -0.3 -0.5 -0.3 -0.4 -0.5 -0.3 -0.4 -0.3 -0.5 -0.5 -0.8 -0.3 -0.4 -0.6 -0.5 -0.3 -0.3 -0.4 -0.3 -0.4 0.3 -0.5 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.0 -0.7 -0.6 -0.6 -0.6 -0.5 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.4 -0.6 -0.6 -0.3 -0.6 -0.8 -0.6 -0.5 -0.8 -0.6 -0.5 -0.6 -0.6 -0.6 -0.5 -0.4 -0.6 -0.7 -0.5 -0.4 -0.6 -0.3 -0.6 -0.5 -0.5 -1.0 -0.5 0.6 -1.0 -0.7
Relative age voice broke 0.0 0.0 0.2 0.1 -0.0 0.3 0.1 0.1 -0.1 0.1 0.1 0.1 0.1 0.2 0.1 -0.1 -0.2 0.1 0.3 0.4 0.0 -0.1 0.1 0.1 0.3 0.0 0.0 -0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.2 -0.1 0.1 0.1 0.1 0.2 0.4 0.4 -0.1 0.3 -0.0
Taking other prescription medications 1.0 1.5 2.7 -1.4 -1.2 -1.4 -1.3 -1.2 -1.1 -1.0 -1.1 -1.0 -1.1 -1.0 -1.0 -0.9 -1.1 -1.4 -1.4 -0.8 -1.2 -1.3 -1.2 -1.2 -1.6 -1.2 -1.2 -1.4 -1.2 -1.2 -1.2 -1.2 -1.4 -1.2 -1.1 -1.1 -1.3 -1.5 -1.1 -1.0 -1.1 -1.4 -1.4 1.5 -1.6 -1.2
Age when periods started (menarche) 1.4 3.4 6.8 -1.3 -1.9 -2.6 -1.8 -1.6 -1.8 -1.9 -1.8 -1.9 -1.6 -1.9 -1.9 -1.6 -2.2 -2.2 -1.6 -1.9 -1.9 -1.9 -1.9 -2.0 -1.9 -1.9 -2.0 -1.8 -1.7 -1.8 -2.0 -1.9 -1.6 -2.0 -1.8 -2.0 -2.2 -1.8 -1.8 -2.2 -1.9 -1.0 -1.6 1.5 -1.5 -1.8
Bilateral oophorectomy (both ovaries removed) 1.6 1.9 2.7 -1.4 -1.3 -1.0 -1.5 -1.3 -1.6 -1.4 -1.4 -1.4 -1.4 -1.5 -1.5 -1.5 -0.9 -1.3 -1.2 -1.0 -1.4 -1.5 -1.4 -1.4 -1.5 -1.3 -1.3 -1.5 -1.5 -1.5 -1.3 -1.5 -1.2 -1.3 -1.4 -1.2 -1.5 -1.3 -1.3 -1.1 -1.2 -1.6 -1.3 1.2 -1.7 -1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.7 0.1 0.4 0.8 0.4 0.4 0.2 0.5 0.4 0.8 0.3 0.3 0.4 0.1 0.3 0.2 0.5 -0.2 0.4 0.7 0.4 0.3 0.3 0.4 0.6 0.0 0.2 0.2 0.2 -0.1 0.8 0.3 0.6 0.3 0.5 0.8 0.4 0.1 0.3 -0.5 0.5 -0.0 0.5 0.6
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 1.5 1.0 0.9 0.8 0.8 0.9 0.8 0.9 0.8 1.0 0.8 0.9 0.9 0.7 1.1 0.9 0.9 1.2 0.9 1.0 0.8 1.0 0.8 0.8 0.9 0.9 0.9 0.8 1.0 0.8 0.6 0.8 0.9 1.0 1.0 0.8 0.7 1.2 0.9 -0.0 0.7 -0.3 0.9 0.8
Qualifications: CSEs or equivalent 1.8 2.4 3.8 -1.3 -1.6 -1.9 -1.7 -1.8 -1.5 -1.4 -1.6 -1.2 -1.6 -1.4 -1.5 -1.8 -1.4 -1.3 -1.7 -1.7 -1.6 -1.5 -1.6 -1.5 -1.7 -1.6 -1.5 -1.2 -1.6 -1.6 -1.8 -1.4 -1.8 -2.0 -1.5 -1.7 -1.3 -0.9 -1.4 -1.7 -1.7 -1.0 -1.7 1.7 -1.4 -1.5
Serious illness, injury or assault to yourself 0.2 0.2 0.4 -0.4 -0.5 -0.5 -0.5 -0.4 -0.4 -0.5 -0.5 -0.5 -0.5 -0.4 -0.5 -0.4 -0.5 -0.5 -0.6 -0.4 -0.5 -0.6 -0.5 -0.4 -0.6 -0.5 -0.6 -0.6 -0.5 -0.6 -0.6 -0.4 -0.2 -0.4 -0.4 -0.6 -0.5 -0.6 -0.5 -0.6 -0.6 0.3 -0.4 0.3 -0.4 -0.6
High blood pressure 1.2 3.3 8.1 -2.0 -1.7 -1.8 -1.7 -1.6 -1.9 -1.9 -1.8 -1.7 -1.7 -1.8 -1.9 -1.7 -1.5 -1.6 -1.9 -1.9 -1.7 -1.6 -1.7 -2.0 -2.2 -1.7 -1.6 -1.9 -1.8 -1.8 -1.8 -1.9 -1.6 -1.8 -1.7 -1.8 -1.7 -1.8 -1.9 -1.8 -1.8 -2.9 -1.7 1.3 -2.1 -1.7
Hayfever, allergic rhinitis or eczema 0.1 0.1 1.8 -0.3 0.1 1.4 0.0 0.2 -0.0 0.0 0.1 0.4 -0.1 -0.0 -0.0 0.2 0.1 -0.1 -0.0 0.8 0.1 0.2 0.2 0.4 0.2 0.2 0.3 -0.0 -0.0 0.1 0.3 -0.0 0.3 0.6 0.1 0.6 0.2 0.3 0.1 0.5 0.5 -0.6 0.2 -0.2 -0.1 0.2
Multivitamins +/- minerals 4.0 5.1 6.7 2.1 2.3 1.4 2.3 2.4 2.3 2.2 2.3 2.2 2.2 2.2 2.1 2.4 2.4 2.4 2.0 2.5 2.2 2.1 2.2 2.4 2.3 2.3 2.3 2.5 2.3 2.3 2.4 2.1 2.5 2.3 2.4 2.5 2.1 2.4 2.2 2.3 2.4 1.2 2.6 -2.1 2.4 2.3
Stomach or abdominal pain in last month 0.8 1.1 1.9 -1.3 -1.0 -1.1 -1.2 -1.0 -1.0 -1.0 -1.0 -1.0 -1.1 -1.0 -1.0 -1.0 -0.6 -0.8 -1.2 -0.3 -1.1 -1.2 -1.0 -0.9 -1.0 -1.0 -1.0 -1.1 -1.0 -1.3 -0.9 -1.4 -1.0 -0.6 -1.1 -0.7 -1.3 -1.1 -0.9 -0.7 -0.8 -1.3 -1.0 1.2 -1.2 -1.0
Supplements: Glucosamine 0.0 0.0 0.2 0.3 0.0 -0.0 -0.1 0.0 0.1 0.1 0.0 0.2 -0.1 0.0 0.1 0.1 0.1 0.1 -0.3 0.3 -0.0 -0.1 -0.0 0.0 0.1 0.0 0.0 0.2 -0.0 -0.1 0.1 -0.2 -0.2 0.4 -0.1 0.1 -0.3 0.1 0.0 0.1 0.1 -0.5 -0.2 0.4 0.0 -0.0
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 0.7 0.5 0.5 0.0 0.4 0.4 0.5 0.6 0.5 0.5 0.6 0.5 0.6 0.4 0.6 0.6 0.8 0.8 0.5 0.5 0.4 0.5 0.7 0.5 0.6 0.6 0.5 0.3 0.6 0.4 0.2 0.6 0.4 0.6 0.2 0.7 0.5 0.8 0.6 0.1 0.4 -0.1 0.5 0.5
Medication: Atenolol 6.3 7.9 12.6 -3.0 -2.9 -3.5 -2.8 -2.8 -2.8 -2.5 -2.7 -2.6 -2.7 -2.5 -2.4 -2.8 -2.8 -2.7 -2.7 -2.8 -2.8 -2.8 -3.0 -2.7 -3.0 -2.9 -2.8 -2.8 -2.6 -2.9 -2.9 -2.7 -2.8 -2.7 -2.7 -3.0 -2.9 -3.0 -2.6 -2.8 -3.0 -2.6 -2.9 3.1 -2.6 -2.9
Medication: Levothyroxine sodium 1.2 2.1 6.6 -0.8 -1.4 -0.4 -1.2 -1.2 -1.2 -1.1 -1.3 -0.5 -1.4 -1.2 -1.1 -1.2 -1.8 -1.4 -1.5 -2.1 -1.3 -0.8 -1.4 -1.9 -1.8 -1.4 -1.1 -1.5 -2.0 -1.5 -1.8 -2.0 -1.0 -1.4 -1.2 -1.7 -1.1 -0.8 -1.3 -1.9 -1.6 -2.6 -1.3 2.0 -1.3 -1.1
Sitting height 0.6 4.3 8.9 3.0 2.1 1.6 2.2 2.4 2.0 2.4 2.2 2.4 2.3 2.3 2.4 2.0 1.8 1.8 2.0 1.2 2.0 2.4 2.0 1.6 1.9 2.1 2.2 1.7 2.0 2.0 1.7 2.0 2.6 1.8 2.2 1.6 1.6 2.5 2.3 1.9 1.8 2.5 2.1 -1.4 1.9 2.1
Chronic bronchitis/emphysema (father) 0.3 0.3 1.0 -0.3 -0.5 -1.0 -0.5 -0.6 -0.5 -0.7 -0.7 -0.4 -0.6 -0.7 -0.7 -0.5 -0.1 -0.4 -0.7 -0.2 -0.5 -0.3 -0.6 -0.6 -0.8 -0.5 -0.4 -0.3 -0.6 -0.6 -0.4 -0.7 -0.4 -0.1 -0.4 -0.4 -0.8 -0.6 -0.8 -0.2 -0.4 -0.9 -0.4 0.5 -1.0 -0.5
High blood pressure (mother) 0.1 0.2 0.9 -0.1 -0.4 -0.0 -0.4 -0.4 -0.4 -0.3 -0.3 -0.3 -0.4 -0.3 -0.3 -0.5 -0.3 -0.2 -0.4 -0.3 -0.3 -0.6 -0.4 -0.7 -0.2 -0.4 -0.4 -0.0 -0.5 -0.3 -0.3 -0.2 -0.6 -0.8 -0.4 -0.4 -0.7 -0.3 -0.3 -0.1 -0.4 -0.3 -0.5 0.3 -0.9 -0.4
Body mass index (BMI) 0.8 3.3 8.0 1.4 2.0 2.2 1.9 1.8 1.9 1.2 1.6 1.2 1.8 1.3 1.2 1.7 2.3 2.0 2.0 2.1 2.0 1.8 1.9 1.6 1.6 2.0 1.9 1.9 1.6 1.9 2.1 1.8 1.8 1.9 1.8 2.2 1.7 1.5 1.4 2.3 2.1 0.6 1.8 -2.8 0.9 1.8
Impedance of leg (left) 1.7 8.5 11.4 -2.6 -3.2 -1.7 -3.1 -2.8 -3.1 -2.9 -3.0 -2.6 -3.3 -2.9 -2.9 -3.0 -3.0 -3.2 -2.7 -3.4 -3.1 -2.9 -3.0 -2.8 -2.8 -3.1 -3.0 -2.8 -3.2 -3.1 -3.2 -3.0 -2.7 -2.7 -3.1 -3.2 -2.4 -2.5 -2.9 -3.3 -3.2 -2.4 -2.9 3.1 -2.0 -3.0
Leg predicted mass (left) 1.9 10.1 13.0 3.2 3.4 2.6 3.4 3.3 3.3 3.1 3.3 3.1 3.5 3.1 3.2 3.0 3.4 3.3 3.2 3.2 3.3 3.5 3.2 2.8 3.0 3.4 3.4 2.8 3.0 3.2 3.4 2.9 3.3 3.3 3.4 3.4 2.7 3.1 3.1 3.6 3.4 2.2 3.2 -3.1 2.2 3.4
Trunk fat mass 1.5 6.5 13.4 2.6 2.6 3.7 2.6 2.6 2.5 1.9 2.3 2.3 2.4 2.0 2.0 2.2 3.0 2.6 2.9 2.6 2.6 2.7 2.7 2.1 2.3 2.6 2.7 2.6 2.1 2.6 2.7 2.2 2.9 3.0 2.5 2.8 2.8 2.6 2.1 3.0 2.8 1.0 2.8 -3.1 1.9 2.6
Waist circumference 1.2 4.4 7.3 2.0 2.2 2.7 2.1 2.1 2.0 1.7 2.0 1.9 2.0 1.7 1.7 1.9 2.5 2.2 2.3 2.2 2.1 2.2 2.2 1.8 1.7 2.2 2.2 2.0 1.9 2.2 2.2 1.9 2.3 2.4 2.1 2.3 2.1 1.9 1.9 2.4 2.3 0.9 2.1 -2.5 1.4 2.2
Number of incorrect matches in round 0.6 1.0 4.9 -0.8 -0.9 -0.2 -0.9 -1.1 -1.0 -1.2 -1.1 -0.9 -1.0 -1.2 -1.2 -1.2 -0.8 -0.8 -0.7 -1.0 -0.9 -0.9 -0.9 -1.1 -0.9 -1.0 -0.9 -0.6 -1.2 -0.9 -0.9 -0.9 -0.8 -1.1 -1.1 -0.9 -1.0 -0.6 -1.3 -1.0 -1.0 -2.2 -1.0 0.7 -0.9 -0.9
Past tobacco smoking 0.7 1.3 2.1 -1.0 -1.2 -1.3 -1.2 -1.4 -0.9 -1.4 -1.3 -1.3 -1.1 -1.4 -1.4 -1.1 -1.1 -1.1 -1.2 -0.8 -1.3 -1.0 -1.2 -1.2 -1.4 -1.2 -1.1 -0.8 -1.3 -1.0 -1.1 -1.0 -1.2 -0.5 -1.4 -0.9 -0.9 -1.0 -1.4 -0.8 -1.0 -1.2 -1.1 1.2 -1.4 -1.1
Alcohol usually taken with meals 0.2 0.4 2.3 -0.3 -0.7 0.0 -0.5 -0.7 -0.4 -0.1 -0.4 0.2 -0.6 -0.2 -0.1 -0.7 -0.9 -0.4 -0.6 -1.0 -0.7 -0.3 -0.6 -0.8 -0.7 -0.7 -0.4 -0.5 -0.7 -0.5 -0.8 -0.7 -0.3 -0.5 -0.5 -0.8 -0.1 -0.5 -0.3 -0.9 -0.7 -0.5 -0.5 1.5 -0.5 -0.4
Nervous feelings 0.1 0.2 1.3 -0.5 -0.4 -0.5 -0.4 -0.4 -0.2 -0.3 -0.3 -0.1 -0.4 -0.3 -0.2 -0.2 -0.4 -0.4 -0.7 -0.4 -0.3 -0.4 -0.4 -0.7 -0.7 -0.3 -0.3 -0.2 -0.4 -0.2 -0.4 -0.2 -0.5 -0.3 -0.4 -0.3 -0.3 -0.1 -0.2 -0.3 -0.3 -0.5 -0.5 0.6 -1.1 -0.2
Frequency of tenseness / restlessness in last 2 weeks 2.0 3.1 4.5 -2.0 -1.8 -1.7 -1.7 -1.5 -1.7 -2.0 -1.8 -1.9 -1.7 -1.9 -2.0 -1.6 -1.6 -1.8 -2.0 -1.5 -1.7 -2.0 -1.8 -1.7 -1.9 -1.7 -1.9 -2.1 -1.8 -1.7 -1.7 -1.9 -1.5 -1.8 -1.8 -1.6 -1.5 -1.8 -1.9 -1.8 -1.6 -1.7 -1.6 1.1 -2.1 -1.8
Hearing difficulty/problems with background noise 0.0 0.1 0.3 -0.1 -0.2 -0.1 -0.1 -0.1 -0.2 0.0 -0.1 0.3 -0.3 -0.1 -0.0 -0.1 -0.4 -0.1 -0.0 -0.5 -0.2 0.1 -0.1 -0.5 -0.3 -0.2 -0.1 -0.1 -0.3 -0.2 -0.3 -0.3 0.0 -0.1 -0.0 -0.3 -0.2 -0.0 -0.2 -0.5 -0.3 -0.6 -0.1 0.5 -0.2 -0.1
Hair/balding pattern: Pattern 2 0.3 0.4 0.7 0.4 0.6 0.3 0.6 0.6 0.7 0.5 0.5 0.5 0.6 0.6 0.5 0.6 0.7 0.5 0.5 0.8 0.6 0.8 0.6 0.8 0.4 0.6 0.7 0.4 0.8 0.3 0.7 0.4 0.5 0.8 0.6 0.6 0.8 0.7 0.5 0.8 0.6 -0.3 0.6 -0.2 0.7 0.6
Had menopause 1.1 1.4 2.1 -1.2 -1.2 -0.9 -1.2 -1.4 -1.2 -1.3 -1.3 -1.4 -1.3 -1.3 -1.2 -1.1 -1.1 -1.2 -1.1 -0.8 -1.3 -1.4 -1.2 -1.1 -1.1 -1.3 -1.4 -1.0 -1.1 -1.3 -1.1 -0.9 -1.4 -1.1 -1.4 -1.1 -1.3 -1.4 -1.3 -0.8 -1.1 -0.7 -1.1 1.1 -1.3 -1.4
Had other major operations 0.1 0.1 0.4 -0.2 -0.2 -0.3 -0.3 -0.2 -0.2 -0.4 -0.3 -0.4 -0.3 -0.3 -0.3 -0.3 -0.1 -0.1 -0.2 -0.2 -0.3 -0.3 -0.3 -0.5 -0.2 -0.3 -0.3 -0.0 -0.5 -0.3 -0.2 -0.5 -0.2 -0.2 -0.2 -0.3 -0.5 -0.6 -0.4 -0.3 -0.3 -0.5 -0.2 0.2 -0.4 -0.3
Forced vital capacity (FVC) 0.1 0.2 1.0 1.0 0.4 -0.3 0.4 0.4 0.4 0.8 0.5 0.8 0.6 0.7 0.9 0.3 0.2 0.3 0.4 -0.1 0.5 0.7 0.3 0.3 0.4 0.3 0.6 0.0 0.4 0.2 0.2 0.2 0.3 0.1 0.6 0.1 -0.0 0.8 0.6 0.2 0.2 0.5 0.2 0.5 0.6 0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.1 0.4 -0.2 -0.0 0.2 0.1 -0.0 -0.1 0.3 0.1 0.7 -0.0 0.0 0.2 -0.2 -0.3 -0.0 0.2 -0.6 0.1 0.4 -0.0 -0.1 -0.0 -0.0 0.3 -0.3 -0.3 -0.3 -0.3 -0.7 0.3 -0.1 0.4 -0.1 0.1 0.5 0.1 -0.3 -0.1 -0.7 0.1 0.6 0.3 0.2
Ever unenthusiastic/disinterested for a whole week 7.1 8.6 10.8 -2.8 -3.0 -2.7 -3.0 -3.0 -3.0 -2.8 -3.0 -2.8 -3.0 -2.8 -2.8 -3.3 -3.0 -2.7 -3.1 -2.9 -3.0 -3.0 -3.0 -2.7 -2.7 -3.0 -3.1 -3.1 -3.0 -3.1 -3.0 -2.9 -3.0 -3.3 -3.0 -3.0 -2.9 -2.8 -2.9 -2.8 -3.0 -2.5 -3.1 2.8 -2.6 -3.1
Qualifications: None of the above 2.9 6.2 9.1 -3.0 -2.4 -2.7 -2.5 -2.7 -2.5 -2.9 -2.6 -3.0 -2.4 -2.8 -2.9 -2.5 -2.3 -2.6 -2.1 -2.1 -2.3 -2.8 -2.4 -2.4 -2.3 -2.4 -2.6 -2.1 -2.4 -2.3 -2.2 -2.4 -2.7 -3.0 -2.4 -2.2 -2.5 -2.7 -2.7 -2.2 -2.3 -1.8 -2.5 1.2 -2.9 -2.5
Financial difficulties in last 2 years 0.5 0.7 1.8 -1.0 -0.9 -1.2 -0.8 -0.8 -0.8 -0.7 -0.8 -0.4 -0.8 -0.8 -0.7 -0.7 -0.8 -0.9 -0.9 -0.4 -0.8 -0.6 -0.9 -0.8 -1.2 -0.8 -0.6 -0.7 -0.9 -0.9 -0.8 -1.0 -0.7 -0.3 -0.5 -0.7 -0.6 -0.7 -0.8 -0.6 -0.7 -1.4 -0.6 1.2 -1.0 -0.7
Mouth/teeth dental problems 0.5 0.8 2.1 1.0 0.9 0.9 0.9 0.8 0.9 1.2 0.9 1.3 0.8 1.1 1.2 0.9 1.0 1.0 0.8 0.7 0.8 1.1 0.9 0.8 0.9 0.8 1.1 0.7 0.6 0.6 0.8 0.8 0.9 1.0 0.6 0.7 0.8 1.4 1.0 0.9 0.7 0.2 0.9 0.1 1.0 0.9
Heart attack 0.4 0.5 1.0 0.4 0.7 0.8 0.7 0.6 0.7 0.8 0.8 1.0 0.7 0.8 0.9 0.9 0.6 0.8 0.6 0.7 0.8 0.8 0.7 0.5 0.4 0.7 0.8 0.7 0.5 0.7 0.7 0.4 0.5 0.7 0.8 0.7 0.8 0.6 0.7 0.7 0.7 -0.2 0.6 -0.1 0.3 0.8
Allergy 0.4 0.9 3.8 -0.7 -1.0 -2.0 -0.9 -0.9 -0.8 -0.7 -0.9 -1.0 -0.8 -0.6 -0.7 -1.1 -0.9 -0.6 -0.7 -1.4 -1.0 -0.9 -0.9 -1.1 -1.0 -1.0 -1.0 -0.9 -0.8 -0.9 -1.1 -0.8 -0.9 -1.1 -0.9 -1.3 -0.7 -1.0 -0.8 -1.4 -1.2 -0.4 -0.9 1.3 -0.4 -1.0
Pain all over the body in last month 0.4 0.4 1.1 -0.2 -0.6 0.2 -0.5 -0.6 -0.5 -0.3 -0.5 -0.2 -0.6 -0.4 -0.4 -0.7 -0.7 -0.3 -0.5 -0.9 -0.5 -0.4 -0.6 -0.8 -0.5 -0.6 -0.5 -0.4 -0.8 -0.5 -0.6 -1.0 -0.7 -0.8 -0.5 -0.7 -0.3 -0.4 -0.6 -0.9 -0.7 -0.9 -0.5 1.1 -0.8 -0.5
Diabetes (self-reported) 0.8 1.2 1.9 0.8 1.1 1.0 1.1 1.1 1.0 1.0 1.0 1.1 0.9 0.9 1.0 1.1 1.3 1.2 1.4 1.1 1.0 1.2 1.1 1.0 1.0 1.0 1.2 1.0 1.2 1.0 1.1 1.1 1.3 1.3 1.0 1.1 1.2 1.1 1.0 1.2 1.1 0.5 1.3 -0.9 1.2 1.1
Hayfever/allergic rhinitis (self-reported) 1.2 1.5 3.0 1.1 1.3 1.7 1.3 1.3 1.2 1.2 1.3 1.4 1.2 1.2 1.3 1.0 1.4 1.1 1.1 1.1 1.3 1.5 1.3 1.3 1.1 1.3 1.4 0.6 1.0 1.2 1.3 1.2 1.3 1.6 1.1 1.3 1.4 1.5 1.2 1.4 1.3 0.2 1.3 -0.9 0.8 1.3
Medication: Ramipril 0.1 0.1 0.8 0.2 0.2 0.9 0.2 0.2 0.2 0.4 0.3 0.3 0.1 0.4 0.4 0.0 -0.1 0.3 0.2 -0.0 0.2 0.3 0.2 0.0 0.1 0.2 0.3 -0.2 0.3 0.2 0.2 0.2 -0.1 0.1 0.2 0.1 0.6 0.3 0.4 0.2 0.1 0.5 0.0 0.1 0.2 0.2
Medication: Simvastatin 0.0 0.0 0.3 -0.5 -0.1 0.5 0.0 0.1 -0.1 -0.1 0.0 0.1 -0.2 -0.1 -0.0 0.1 -0.3 -0.2 -0.1 -0.4 -0.1 -0.1 -0.0 -0.2 -0.2 -0.0 -0.1 -0.5 -0.2 -0.1 -0.1 -0.3 0.1 -0.1 -0.1 -0.1 -0.3 -0.2 -0.0 -0.1 -0.1 -0.3 0.0 -0.1 -0.3 -0.0
Fluid intelligence score 1.7 3.6 6.5 2.2 1.9 2.6 2.0 2.1 2.0 2.1 2.1 2.3 1.9 2.2 2.2 2.0 1.5 1.6 1.5 1.2 2.0 2.2 2.0 1.8 1.8 2.0 2.0 1.2 1.9 1.9 1.7 1.7 1.9 1.9 2.0 1.6 1.8 1.8 2.2 1.5 1.7 1.8 1.6 -1.5 2.2 2.0
Illnesses of siblings 0.6 0.8 1.9 0.9 0.9 0.8 1.0 0.9 1.0 0.9 0.9 1.0 0.8 0.9 0.9 1.1 0.8 0.7 0.7 0.6 1.0 1.0 0.9 0.8 0.9 0.9 1.0 0.7 0.9 0.7 0.8 1.0 0.9 1.1 1.0 0.8 1.2 1.4 0.9 0.6 0.8 0.7 0.7 -0.9 1.3 0.9
Neuroticism score 0.3 0.6 2.6 -0.8 -0.7 -1.6 -0.8 -0.7 -0.6 -0.8 -0.7 -0.8 -0.6 -0.8 -0.8 -0.6 -0.5 -0.7 -0.9 -0.4 -0.7 -0.7 -0.7 -0.9 -1.1 -0.7 -0.7 -0.8 -0.7 -0.6 -0.6 -0.8 -0.8 -0.7 -0.7 -0.6 -1.0 -0.7 -0.8 -0.6 -0.6 -0.9 -0.7 0.7 -1.2 -0.7
Weight 1.1 5.5 7.8 2.3 2.5 2.7 2.4 2.4 2.4 2.0 2.3 2.1 2.4 2.0 2.1 2.1 2.6 2.5 2.5 2.3 2.5 2.5 2.4 2.0 2.1 2.5 2.5 2.1 2.1 2.4 2.5 2.1 2.5 2.5 2.4 2.5 2.2 2.2 2.1 2.7 2.5 1.4 2.4 -2.8 1.5 2.4
Impedance of arm (right) 0.1 0.5 1.6 0.1 -0.9 0.4 -0.8 -0.4 -0.7 -0.4 -0.6 -0.2 -1.0 -0.5 -0.5 -0.7 -0.9 -0.6 -0.7 -1.1 -1.0 -0.6 -0.7 -0.7 -0.5 -0.8 -0.7 -0.4 -0.7 -0.7 -0.9 -0.6 -0.4 -0.0 -0.7 -0.9 0.2 -0.0 -0.6 -1.1 -0.9 -0.2 -0.5 1.3 0.1 -0.7
Arm fat percentage (right) 1.4 5.6 12.0 2.2 2.4 3.5 2.3 2.4 2.4 1.8 2.2 2.0 2.2 1.9 1.8 2.2 2.7 2.6 2.6 2.5 2.4 2.3 2.5 2.0 2.1 2.4 2.4 2.5 2.0 2.5 2.6 2.2 2.4 2.6 2.3 2.6 2.6 2.5 1.9 2.6 2.6 0.9 2.4 -2.9 1.8 2.4
Trunk fat-free mass 0.9 5.0 6.9 2.3 2.4 1.4 2.4 2.4 2.3 2.5 2.4 2.3 2.6 2.4 2.5 2.2 2.2 2.2 2.1 2.1 2.4 2.5 2.3 2.0 2.1 2.4 2.5 1.6 2.2 2.2 2.3 2.1 2.3 2.2 2.4 2.3 1.5 2.0 2.4 2.5 2.3 1.9 2.2 -2.0 1.6 2.4
Hip circumference 1.5 6.3 9.1 2.5 2.7 2.5 2.5 2.5 2.6 2.3 2.5 2.4 2.6 2.2 2.3 2.3 3.0 2.6 2.7 2.6 2.6 2.7 2.6 2.1 2.1 2.7 2.8 2.6 2.2 2.7 2.6 2.4 2.6 2.7 2.6 2.8 2.5 2.5 2.3 3.0 2.7 1.2 2.5 -2.5 1.5 2.6
Time employed in main current job 0.4 0.4 1.7 0.5 0.6 0.1 0.5 0.5 0.5 0.8 0.7 0.5 0.5 0.8 0.7 0.7 0.6 0.7 0.6 1.2 0.4 0.2 0.6 0.7 0.8 0.5 0.4 0.9 0.9 0.5 0.7 0.8 0.5 0.7 0.6 0.8 0.5 0.4 0.8 0.7 0.7 1.3 0.6 -0.4 0.7 0.4
Alcohol intake versus 10 years previously 1.0 1.5 2.3 -1.2 -1.2 -0.8 -1.1 -1.2 -1.2 -1.3 -1.2 -1.1 -1.1 -1.2 -1.3 -1.3 -1.4 -1.3 -1.0 -1.3 -1.1 -1.0 -1.1 -1.4 -1.4 -1.2 -1.2 -1.4 -1.2 -1.2 -1.2 -1.5 -1.1 -1.4 -1.0 -1.2 -1.2 -1.2 -1.3 -1.4 -1.2 -1.1 -1.1 1.1 -1.0 -1.1
Father’s age at death 0.0 0.0 0.2 -0.3 0.1 -0.1 -0.0 0.1 -0.1 0.1 0.1 0.1 0.0 -0.0 0.2 -0.1 0.3 -0.1 0.1 -0.1 -0.0 0.0 0.0 0.1 -0.1 0.1 0.1 0.0 0.1 0.1 -0.0 -0.1 -0.0 0.2 0.1 0.0 0.5 -0.3 0.2 0.3 0.1 0.5 -0.0 0.2 0.1 0.1
Worrier / anxious feelings 0.3 0.6 2.4 -0.8 -0.7 -1.5 -0.7 -0.7 -0.6 -0.8 -0.7 -0.8 -0.6 -0.8 -0.8 -0.7 -0.6 -0.6 -0.8 -0.6 -0.7 -0.7 -0.7 -1.0 -1.0 -0.7 -0.7 -0.9 -0.7 -0.6 -0.6 -0.7 -0.7 -0.5 -0.7 -0.6 -0.7 -0.5 -0.8 -0.7 -0.6 -1.0 -0.7 0.8 -1.2 -0.7
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 2.8 -0.9 -1.1 -0.5 -1.3 -1.0 -1.1 -0.8 -1.1 -1.0 -1.2 -0.9 -0.8 -1.1 -0.9 -0.8 -1.3 -0.8 -1.2 -1.1 -1.2 -1.1 -1.0 -1.1 -1.1 -1.2 -1.3 -1.2 -1.0 -1.2 -1.4 -0.7 -1.2 -1.0 -1.1 -0.9 -1.0 -0.8 -1.1 -1.3 -1.4 1.7 -1.2 -1.2
Falls in the last year 0.4 0.5 1.2 -0.8 -0.6 -0.7 -0.7 -0.8 -0.7 -1.1 -0.9 -1.1 -0.7 -0.9 -1.0 -0.5 -0.4 -0.5 -0.7 -0.0 -0.6 -0.9 -0.6 -0.3 -0.5 -0.6 -0.8 -0.2 -0.6 -0.6 -0.4 -0.3 -0.9 -0.5 -0.7 -0.4 -0.9 -0.9 -1.0 -0.3 -0.5 -0.9 -0.6 0.1 -1.0 -0.8
Hair/balding pattern: Pattern 3 0.0 0.1 0.5 0.1 -0.1 -0.7 -0.2 -0.1 -0.1 0.2 0.1 0.3 -0.1 0.1 0.2 -0.1 -0.3 -0.2 -0.1 -0.1 -0.2 -0.1 -0.2 -0.2 -0.1 -0.1 -0.0 0.5 -0.0 -0.0 -0.2 -0.1 -0.1 0.3 0.2 -0.1 0.3 -0.2 0.2 -0.3 -0.1 -0.2 -0.2 0.6 -0.2 0.0
Number of live births 0.5 0.7 2.3 0.7 0.8 0.3 0.8 0.8 0.9 0.7 0.8 0.5 0.9 0.8 0.7 1.0 0.7 0.5 0.8 0.9 0.9 0.6 0.8 0.9 0.8 0.8 0.7 0.6 1.3 0.7 0.8 1.2 0.7 0.5 0.8 0.8 0.6 0.7 0.9 0.8 0.8 1.5 0.8 -1.2 1.1 0.7
Forced expiratory volume in 1-second (FEV1) 0.0 0.2 0.6 0.7 0.2 0.0 0.2 0.2 0.3 0.8 0.5 0.6 0.4 0.6 0.8 0.1 0.1 0.3 0.2 0.0 0.2 0.5 0.2 0.3 0.3 0.2 0.4 -0.1 0.4 0.0 0.1 0.1 0.0 0.1 0.4 0.1 0.1 0.7 0.6 0.3 0.1 0.6 0.1 0.6 0.5 0.3
Pulse rate 0.1 0.2 0.7 0.0 -0.5 -0.5 -0.4 -0.3 -0.2 -0.7 -0.5 -0.5 -0.2 -0.6 -0.7 -0.4 -0.7 -0.5 -0.7 -0.6 -0.4 -0.3 -0.4 -0.6 -0.8 -0.4 -0.3 -0.5 -0.7 -0.3 -0.5 -0.4 -0.2 -0.1 -0.4 -0.4 -0.2 -0.3 -0.6 -0.5 -0.4 -0.8 -0.4 0.1 -0.8 -0.3
Happiness 0.1 0.1 0.5 0.5 -0.1 0.2 -0.1 -0.2 0.0 0.4 0.1 0.2 -0.1 0.4 0.4 -0.3 -0.2 0.2 -0.0 -0.2 0.0 -0.2 -0.1 0.0 0.4 -0.1 -0.1 -0.1 -0.0 -0.2 -0.1 -0.2 -0.4 -0.7 0.0 -0.2 -0.4 0.3 0.1 -0.0 -0.2 -0.0 -0.2 0.4 0.3 -0.1
Noisy workplace 0.5 0.6 2.4 0.5 0.7 0.6 0.7 0.8 0.7 -0.0 0.4 0.2 0.7 0.1 -0.0 0.8 1.0 0.6 0.9 1.4 0.7 0.7 0.7 0.7 0.6 0.7 0.7 0.8 0.6 0.6 1.0 0.6 0.9 0.8 0.7 1.1 0.7 0.9 0.1 0.9 1.0 -0.9 1.0 -1.6 0.3 0.7
Qualifications: A levels/AS levels or equivalent 0.9 2.1 6.7 2.0 1.3 1.0 1.4 1.5 1.4 1.9 1.6 1.8 1.4 1.9 1.9 1.6 0.9 1.1 1.0 0.6 1.2 1.3 1.3 1.4 1.2 1.3 1.3 1.1 1.8 1.3 0.9 1.7 1.6 0.9 1.5 0.8 1.1 1.4 1.9 0.7 1.0 2.6 1.3 -0.8 2.1 1.3
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.1 2.4 1.1 0.9 1.0 1.0 1.1 0.9 1.0 1.0 1.2 0.9 0.9 1.0 1.0 1.2 1.0 1.4 1.2 0.8 1.2 1.0 0.9 0.8 1.0 1.2 1.2 1.0 1.0 1.0 0.9 1.2 1.5 1.1 1.1 1.5 1.3 0.9 1.2 1.1 -0.2 1.4 -0.5 1.0 1.0
Mouth/teeth dental problems: Dentures 0.0 0.1 0.4 0.1 -0.0 -0.0 -0.0 -0.1 -0.1 -0.3 -0.2 -0.5 -0.1 -0.2 -0.3 -0.0 -0.2 0.0 0.1 0.0 0.0 -0.2 -0.1 -0.1 0.2 -0.1 -0.3 0.4 0.2 0.1 0.1 -0.0 -0.3 -0.3 -0.1 -0.0 -0.4 -0.6 -0.3 0.0 -0.0 0.5 -0.1 -0.6 -0.4 -0.2
Asthma 1.0 2.0 4.2 1.2 1.4 2.1 1.4 1.5 1.3 1.3 1.4 1.3 1.3 1.3 1.3 1.6 1.2 1.2 1.1 1.6 1.4 1.3 1.4 1.5 1.5 1.4 1.4 1.1 1.5 1.3 1.6 1.4 1.1 1.5 1.3 1.7 0.9 1.5 1.4 1.7 1.6 1.3 1.4 -1.6 1.1 1.4
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.3 -0.6 -0.7 -1.1 -0.8 -0.6 -0.7 -0.7 -0.7 -1.1 -0.6 -0.7 -0.8 -0.6 -0.4 -0.7 -0.7 -0.4 -0.8 -0.7 -0.7 -0.6 -0.6 -0.7 -0.8 -0.7 -0.4 -0.8 -0.5 -0.4 -0.9 -0.5 -0.9 -0.6 -1.1 -0.5 -0.7 -0.6 -0.6 -0.3 -0.8 0.6 -0.7 -0.9
Medication: Cholesterol lowering 0.6 1.0 1.7 0.7 1.0 1.3 1.2 1.2 1.0 1.2 1.2 1.2 1.0 1.1 1.2 1.3 0.6 0.9 1.1 0.3 1.1 1.1 1.1 0.7 0.7 1.1 1.0 0.7 1.0 1.3 0.9 0.8 1.0 0.9 0.9 0.8 0.9 0.5 1.2 0.6 0.9 0.3 1.0 -0.7 0.7 1.2
Depression (self-reported) 0.6 0.7 2.3 0.4 0.8 0.7 0.7 0.7 0.7 1.1 0.9 1.0 0.8 1.0 1.1 0.6 1.1 0.9 0.7 1.5 0.7 0.8 0.7 1.1 0.4 0.8 1.0 0.6 0.8 0.6 1.0 0.7 0.6 0.9 0.8 1.1 1.0 0.8 1.0 1.1 1.0 -0.0 0.8 0.2 0.4 0.7
Medication: Lansoprazole 0.5 0.5 3.3 -1.0 -0.5 -1.0 -0.6 -0.6 -0.7 -0.7 -0.7 -0.7 -0.5 -0.8 -0.7 -0.6 -0.2 -0.5 -0.4 -0.5 -0.6 -0.4 -0.5 -0.8 -1.1 -0.6 -0.6 -0.6 -0.8 -0.5 -0.5 -0.8 -0.6 -0.5 -0.7 -0.5 -0.5 -1.0 -0.8 -0.4 -0.5 -1.8 -0.6 0.8 -1.4 -0.6
Prospective memory result 0.8 0.9 1.7 -1.1 -1.1 -0.2 -1.1 -1.1 -1.1 -1.2 -1.1 -1.3 -1.3 -1.1 -1.2 -0.9 -1.0 -1.0 -0.7 -0.6 -1.2 -1.3 -1.0 -1.0 -0.8 -1.1 -1.1 -0.4 -0.9 -1.0 -0.9 -0.6 -1.1 -0.5 -1.3 -0.8 -0.8 -0.8 -1.1 -0.9 -0.9 -0.4 -0.9 0.6 -0.8 -1.2
Lung cancer (father) 1.4 1.7 2.6 -1.2 -1.4 -1.2 -1.3 -1.2 -1.0 -1.3 -1.2 -1.6 -1.1 -1.2 -1.3 -1.2 -1.6 -1.4 -1.4 -1.4 -1.2 -1.5 -1.3 -1.3 -1.3 -1.3 -1.4 -1.5 -1.1 -1.2 -1.3 -1.1 -1.5 -1.4 -1.2 -1.4 -1.3 -1.2 -1.2 -1.5 -1.3 -0.7 -1.5 0.9 -1.2 -1.3
Illnesses of mother 0.0 0.0 0.2 -0.3 -0.1 -0.5 0.0 0.0 0.0 -0.1 0.0 -0.1 0.0 -0.2 -0.1 0.2 -0.2 -0.4 0.0 -0.3 -0.0 0.1 0.0 -0.1 -0.1 0.0 0.0 -0.2 0.2 -0.1 -0.2 -0.2 0.3 0.4 0.0 -0.1 0.1 0.1 0.0 -0.3 -0.0 0.0 0.1 -0.1 0.3 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.1 0.4 0.4 0.1 -0.1 0.1 0.0 0.0 0.5 0.2 0.3 0.2 0.4 0.5 -0.0 -0.1 0.2 0.1 -0.1 0.1 0.3 0.0 0.1 0.1 0.0 0.2 -0.3 0.1 -0.1 -0.0 -0.1 -0.1 -0.1 0.2 -0.1 -0.1 0.3 0.3 0.1 -0.1 0.4 -0.0 0.6 0.2 0.1
Pulse wave Arterial Stiffness index 0.5 0.6 1.2 1.0 0.7 0.7 0.8 0.9 0.8 0.8 0.8 0.9 0.8 0.8 0.8 1.0 0.5 0.5 0.7 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.8 0.9 0.7 0.8 0.7 0.6 0.9 1.1 0.7 0.7 0.9 0.9 0.8 0.7 0.8 0.5 0.8 -0.6 0.7 0.9
Impedance of arm (left) 0.1 0.3 0.9 0.3 -0.6 0.6 -0.6 -0.2 -0.5 -0.4 -0.5 -0.1 -0.8 -0.4 -0.4 -0.5 -0.6 -0.5 -0.3 -0.8 -0.8 -0.3 -0.5 -0.5 -0.4 -0.6 -0.5 -0.0 -0.5 -0.4 -0.6 -0.4 -0.2 0.3 -0.5 -0.7 0.6 0.2 -0.5 -0.8 -0.6 -0.2 -0.3 1.0 0.5 -0.5
Arm fat mass (right) 1.7 6.9 11.3 2.5 2.7 3.4 2.7 2.7 2.7 2.1 2.5 2.3 2.6 2.1 2.1 2.4 3.0 2.7 2.9 2.8 2.7 2.7 2.7 2.3 2.4 2.7 2.8 2.6 2.3 2.7 2.8 2.4 2.7 2.9 2.6 2.9 2.6 2.6 2.2 3.0 2.9 1.3 2.7 -3.2 1.9 2.7
Trunk predicted mass 0.9 5.4 7.4 2.4 2.5 1.5 2.5 2.5 2.4 2.6 2.5 2.4 2.7 2.5 2.6 2.3 2.3 2.3 2.2 2.2 2.5 2.6 2.4 2.1 2.2 2.5 2.5 1.7 2.3 2.3 2.4 2.1 2.4 2.2 2.5 2.4 1.6 2.1 2.5 2.6 2.4 2.0 2.2 -2.0 1.6 2.5
Standing height 0.2 2.4 5.8 2.4 1.5 1.6 1.6 1.8 1.4 2.0 1.7 2.0 1.6 1.8 2.0 1.2 1.2 1.4 1.4 0.7 1.4 1.8 1.4 1.2 1.6 1.5 1.6 1.0 1.4 1.4 1.2 1.1 1.9 1.7 1.7 1.1 1.3 1.8 1.8 1.3 1.2 2.1 1.5 -0.6 1.5 1.6
Length of working week for main job 0.7 0.8 1.5 0.9 0.8 0.4 0.9 0.8 1.1 1.0 0.9 1.1 0.9 0.9 1.0 0.8 0.6 1.0 0.9 0.7 0.8 1.0 0.9 0.6 0.6 0.8 1.0 0.8 0.9 0.8 0.8 0.3 0.9 1.2 1.0 0.8 1.2 1.1 0.9 0.7 0.8 0.3 1.0 -0.2 1.0 1.0
Exposure to tobacco smoke at home 1.1 1.3 2.5 -1.4 -1.1 -1.3 -1.2 -1.1 -1.2 -1.5 -1.2 -1.6 -1.1 -1.4 -1.5 -1.3 -0.7 -1.2 -1.0 -0.4 -1.3 -1.3 -1.1 -1.0 -1.1 -1.1 -1.2 -1.2 -1.1 -1.1 -1.0 -0.9 -0.9 -0.7 -1.1 -0.8 -0.9 -1.4 -1.2 -0.9 -0.9 -0.7 -1.0 0.4 -1.0 -1.2
Breastfed as a baby 0.3 0.3 1.1 -0.6 -0.6 -1.1 -0.6 -0.7 -0.6 -0.1 -0.4 -0.4 -0.4 -0.2 -0.1 -0.3 -0.9 -0.9 -0.4 -0.7 -0.6 -0.5 -0.6 -0.2 -0.7 -0.6 -0.6 -0.6 -0.2 -0.4 -0.7 0.2 -0.6 -0.9 -0.6 -0.8 -0.6 -0.5 -0.1 -0.7 -0.7 0.5 -0.6 0.9 -0.1 -0.6
Tense / ‘highly strung’ 0.1 0.1 1.3 0.2 0.1 0.9 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.2 0.3 0.3 0.3 0.2 0.0 0.3 0.1 0.2 0.2 -0.2 -0.3 0.2 0.2 -0.1 -0.2 0.2 0.2 -0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.2 0.3 0.2 -1.1 0.1 0.4 -0.3 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 2.2 -1.3 -1.2 -1.1 -1.3 -1.4 -1.3 -1.3 -1.3 -1.3 -1.4 -1.2 -1.2 -1.4 -0.7 -1.0 -1.0 -0.2 -1.4 -1.5 -1.2 -1.0 -1.2 -1.3 -1.3 -0.8 -1.1 -1.2 -1.0 -1.1 -1.3 -1.0 -1.2 -0.8 -1.2 -1.4 -1.3 -0.5 -1.0 -1.5 -1.0 1.2 -1.1 -1.4
Hair/balding pattern: Pattern 4 0.1 0.2 1.4 0.0 -0.4 0.3 -0.3 -0.4 -0.2 -0.0 -0.2 -0.1 -0.5 -0.1 -0.1 -0.3 -0.5 -0.3 -0.2 -0.6 -0.4 -0.6 -0.4 -0.4 -0.2 -0.4 -0.4 -0.3 -0.3 -0.4 -0.5 -0.2 -0.5 -0.7 -0.4 -0.5 -0.4 -0.1 -0.1 -0.6 -0.5 1.2 -0.4 0.6 0.3 -0.4
Birth weight of first child 1.0 1.8 5.5 1.7 1.3 2.4 1.4 1.6 1.2 1.3 1.3 1.4 1.2 1.3 1.3 1.4 1.2 1.2 1.6 1.3 1.3 1.4 1.3 1.2 1.6 1.3 1.4 1.0 1.1 1.2 1.4 1.2 1.4 1.6 1.0 1.4 1.1 1.6 1.2 1.2 1.4 0.4 1.4 -0.9 1.3 1.3
Peak expiratory flow (PEF) 0.1 0.2 1.3 0.7 0.3 1.0 0.3 0.3 0.4 0.6 0.5 0.6 0.3 0.5 0.7 0.2 0.0 0.4 0.2 0.1 0.3 0.4 0.3 0.5 0.6 0.3 0.4 0.0 0.3 0.1 0.2 0.2 0.1 0.2 0.4 0.3 0.3 0.8 0.6 0.5 0.3 1.1 0.3 -0.1 0.6 0.4
Pulse wave reflection index 0.5 0.6 1.8 0.7 0.8 0.6 0.6 0.7 0.8 0.6 0.7 0.7 0.7 0.6 0.6 1.0 0.9 0.6 0.7 1.3 0.6 0.6 0.7 0.8 0.7 0.8 0.7 0.8 0.9 0.5 0.8 0.4 0.8 1.2 0.7 1.0 0.8 0.7 0.8 0.9 0.9 0.1 0.9 -0.7 1.0 0.7
Ever highly irritable/argumentative for 2 days 0.3 0.3 0.6 -0.2 -0.7 -0.4 -0.7 -0.5 -0.6 -0.5 -0.6 -0.6 -0.6 -0.6 -0.5 -0.8 -0.6 -0.7 -0.6 -0.4 -0.6 -0.6 -0.7 -0.6 -0.8 -0.6 -0.5 -0.8 -0.4 -0.6 -0.6 -0.4 -0.7 -0.4 -0.6 -0.5 -0.5 -0.2 -0.5 -0.4 -0.5 -0.5 -0.5 0.7 -0.6 -0.6
Loud music exposure frequency 0.0 0.0 0.5 0.2 -0.0 0.0 -0.0 -0.1 -0.0 -0.2 -0.1 -0.1 -0.1 -0.2 -0.2 -0.1 0.1 0.1 -0.3 -0.0 0.1 0.1 -0.1 -0.1 -0.1 -0.0 -0.0 0.0 -0.2 -0.1 -0.0 0.0 -0.0 -0.3 -0.1 -0.0 -0.6 0.0 -0.2 0.1 -0.0 -0.7 -0.1 -0.1 -0.4 -0.0
Qualifications: O levels/GCSEs or equivalent 0.8 1.3 2.6 1.2 1.2 0.6 1.2 1.2 1.1 1.6 1.3 1.6 1.2 1.5 1.6 1.3 1.0 1.2 1.0 0.6 1.1 1.3 1.1 1.0 0.8 1.1 1.2 0.8 1.5 1.0 0.9 1.2 1.2 1.1 1.2 0.8 1.1 1.0 1.5 0.9 0.9 1.2 1.0 -0.3 1.3 1.2
Mouth/teeth dental problems: Bleeding gums 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.1 0.0 -0.0 0.1 0.0 0.2 0.1 0.5 0.1 0.1 0.1 0.3 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.3 0.5 0.3 0.4 0.2 0.2 0.2 0.2 0.3 0.5 0.2 -0.4 0.4 0.1
Blood clot in the leg (DVT) 0.7 0.9 2.3 -0.7 -0.9 -0.0 -1.1 -1.1 -0.9 -1.0 -1.1 -0.9 -1.1 -1.1 -1.0 -0.9 -0.7 -0.9 -1.0 -0.8 -1.0 -1.0 -0.9 -1.0 -0.9 -1.0 -0.9 -0.6 -1.1 -1.1 -0.9 -0.9 -1.1 -0.7 -1.1 -0.9 -1.3 -0.7 -1.1 -0.6 -0.9 -1.5 -1.1 1.1 -0.8 -1.0
Medication: Paracetamol 0.1 0.2 0.5 0.4 0.4 0.2 0.4 0.3 0.4 0.4 0.3 0.4 0.3 0.3 0.4 0.4 0.7 0.4 0.5 0.5 0.4 0.5 0.4 0.3 0.2 0.4 0.4 0.5 0.3 0.6 0.5 0.2 0.2 0.4 0.4 0.4 0.3 0.2 0.2 0.5 0.4 -0.5 0.4 -0.1 0.2 0.4
Headache pain in last month 0.1 0.1 2.0 -0.3 -0.2 -1.4 -0.3 0.0 -0.1 -0.3 -0.2 -0.7 -0.1 -0.2 -0.3 -0.1 -0.1 -0.4 -0.3 0.3 -0.2 -0.6 -0.2 0.2 -0.1 -0.2 -0.4 0.0 0.1 -0.1 -0.0 0.2 -0.4 0.0 -0.1 -0.0 -0.2 -0.4 -0.2 -0.1 -0.1 0.7 -0.2 -0.3 -0.1 -0.4
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 0.9 -0.4 -0.7 -1.0 -0.9 -0.9 -0.7 -0.8 -0.8 -0.7 -0.8 -0.8 -0.8 -1.0 -0.3 -0.7 -0.8 -0.2 -0.8 -0.7 -0.8 -0.5 -0.4 -0.8 -0.7 -0.3 -0.7 -0.9 -0.6 -0.7 -0.8 -0.5 -0.6 -0.6 -0.7 -0.4 -0.8 -0.3 -0.7 -0.2 -0.7 0.7 -0.6 -0.8
Glaucoma (self-reported) 0.4 0.4 0.8 0.2 0.7 0.6 0.7 0.6 0.8 0.8 0.7 0.7 0.7 0.8 0.7 0.6 0.6 0.7 0.5 0.8 0.7 0.8 0.7 0.6 0.2 0.7 0.8 0.1 0.9 0.6 0.7 0.8 0.3 0.7 0.3 0.7 0.6 0.8 0.7 0.6 0.7 -0.2 0.6 -0.2 0.3 0.7
Gout (self-reported) 0.0 0.1 1.0 -0.3 0.2 0.2 0.3 0.1 0.2 0.0 0.2 -0.0 0.4 0.1 0.0 0.2 -0.0 0.1 0.1 -0.3 0.4 -0.0 0.3 -0.2 0.1 0.3 0.1 -0.2 0.1 0.3 0.1 0.2 0.1 -0.6 0.1 0.1 -0.3 0.1 0.2 -0.1 0.2 0.0 -0.0 -1.0 -0.3 0.3
Hypothyroidism/myxoedema (self-reported) 1.7 3.4 7.3 -1.2 -1.9 -0.8 -1.7 -1.8 -1.7 -1.4 -1.7 -1.1 -1.9 -1.4 -1.4 -1.7 -2.1 -1.8 -1.8 -2.3 -1.8 -1.4 -1.8 -2.2 -2.0 -1.9 -1.7 -2.1 -2.2 -2.0 -2.2 -2.3 -1.6 -1.9 -1.7 -2.2 -1.6 -1.4 -1.6 -2.2 -2.1 -2.4 -1.8 2.7 -1.4 -1.7
Medication: Amlodipine 0.0 0.0 0.2 -0.1 -0.0 0.2 -0.1 -0.1 -0.2 -0.3 -0.1 -0.3 -0.1 -0.2 -0.3 0.1 0.2 -0.1 -0.0 0.4 -0.0 -0.3 0.0 0.1 -0.3 0.0 -0.2 0.1 -0.0 0.0 0.1 0.0 -0.2 -0.1 -0.0 0.1 -0.2 -0.3 -0.2 0.2 0.1 -0.4 0.0 -0.5 -0.2 -0.1
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.4 0.3 0.2 0.5 0.3 0.2 0.1 0.1 0.2 -0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.4 0.4 0.3 0.1 0.2 0.3 0.5 0.2 0.2 0.3 0.3 0.3 0.4 0.6 0.1 0.1 0.1 0.3 -0.3 0.3 0.1 0.5 0.3 0.5 0.3 -0.6 0.2 0.1
Birth weight 1.3 2.7 4.8 1.9 1.7 2.2 1.8 1.9 1.7 1.6 1.7 1.6 1.9 1.7 1.6 1.6 1.4 1.5 1.7 1.4 1.9 1.9 1.7 1.4 1.7 1.7 1.7 1.2 1.5 1.7 1.7 1.6 1.6 1.4 1.8 1.6 1.8 1.6 1.5 1.6 1.6 1.1 1.5 -1.7 1.5 1.8
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.4 0.8 0.8 0.4 0.7 0.7 0.9 0.7 0.7 0.6 0.8 0.8 0.6 0.9 0.8 0.8 0.8 1.1 0.8 0.6 0.8 0.9 0.6 0.8 0.7 0.9 0.9 0.8 0.9 1.2 0.6 0.8 0.7 0.9 0.7 0.9 0.7 0.7 0.9 0.8 0.7 -0.7 0.7 0.7
High blood pressure (siblings) 3.3 4.8 7.3 -2.0 -2.3 -1.9 -2.2 -2.2 -2.2 -2.2 -2.2 -2.2 -2.1 -2.1 -2.1 -2.2 -2.3 -2.1 -2.1 -2.1 -2.3 -2.4 -2.2 -2.3 -2.2 -2.3 -2.3 -2.2 -2.1 -2.1 -2.2 -2.2 -2.2 -2.7 -2.3 -2.2 -2.5 -2.3 -2.2 -2.1 -2.2 -1.3 -2.0 1.9 -2.2 -2.3
Forced vital capacity (FVC), Best measure 0.0 0.1 1.3 0.4 -0.1 -0.6 -0.1 -0.1 -0.2 0.4 0.0 0.3 0.0 0.3 0.4 -0.2 -0.3 -0.1 -0.2 -0.5 -0.1 0.2 -0.2 -0.2 -0.2 -0.2 -0.0 -0.6 -0.1 -0.4 -0.3 -0.2 -0.2 -0.5 0.0 -0.5 -0.6 0.2 0.1 -0.2 -0.4 0.0 -0.3 1.1 0.0 -0.1
Body fat percentage 0.9 3.6 10.6 1.8 1.9 3.3 1.8 1.9 1.8 1.2 1.6 1.5 1.6 1.2 1.2 1.6 2.4 2.0 2.3 2.0 1.9 1.9 2.0 1.5 1.6 1.9 2.0 2.1 1.4 2.0 2.0 1.6 2.1 2.2 1.7 2.2 2.2 2.0 1.3 2.3 2.1 0.3 2.0 -2.5 1.3 1.9
Leg fat percentage (right) 0.4 1.5 6.1 0.9 1.2 2.5 1.2 1.2 1.1 0.6 1.0 0.9 1.1 0.6 0.6 1.0 1.6 1.2 1.7 1.3 1.3 1.2 1.3 0.9 0.9 1.3 1.3 1.3 0.8 1.3 1.4 1.0 1.3 1.2 1.0 1.5 1.3 1.2 0.8 1.6 1.4 -0.1 1.3 -1.9 0.6 1.2
Arm fat-free mass (right) 0.8 3.9 6.2 1.9 2.2 1.3 2.1 2.0 2.0 2.0 2.1 1.9 2.3 1.9 2.1 1.9 2.3 1.9 2.1 2.1 2.2 2.2 2.0 1.8 1.8 2.2 2.2 1.5 1.9 1.9 2.1 1.8 2.0 1.9 2.1 2.1 1.2 1.7 2.0 2.5 2.1 1.5 1.9 -2.0 1.3 2.1
Exposure to tobacco smoke outside home 0.1 0.2 1.4 -0.4 -0.2 0.2 -0.3 -0.3 -0.2 -0.5 -0.4 -0.5 -0.3 -0.5 -0.5 -0.4 -0.0 0.1 -0.2 0.1 -0.3 -0.3 -0.2 -0.5 -0.3 -0.2 -0.2 -0.5 -0.5 -0.5 -0.1 -0.8 -0.1 -0.1 -0.4 -0.1 -0.7 -0.5 -0.5 -0.1 -0.1 -1.2 -0.1 -0.0 -0.7 -0.3
Comparative body size at age 10 0.2 0.7 3.4 0.4 0.7 1.8 0.6 0.6 0.7 0.5 0.7 0.0 0.4 0.6 0.5 0.9 0.5 0.7 0.4 1.0 0.7 0.1 0.6 0.9 1.2 0.7 0.4 0.9 1.1 0.8 1.0 1.3 -0.0 0.8 0.3 0.9 0.5 0.2 0.7 0.9 0.9 1.9 0.3 -1.6 0.5 0.4
Number of full brothers 0.4 0.5 3.1 -0.8 -0.7 -1.8 -0.7 -0.7 -0.6 -0.5 -0.6 -0.7 -0.6 -0.6 -0.5 -0.5 -0.8 -0.6 -0.4 -0.6 -0.7 -0.7 -0.7 -0.5 -0.8 -0.7 -0.7 -0.8 -0.5 -0.5 -0.7 -0.5 -0.8 -0.8 -0.8 -0.7 -0.9 -0.8 -0.6 -0.8 -0.7 -0.5 -0.5 0.9 -0.4 -0.7
Worry too long after embarrassment 0.0 0.1 1.7 -0.3 -0.1 -1.3 -0.1 -0.0 -0.2 0.0 0.0 -0.0 0.1 -0.1 -0.0 0.0 0.1 -0.3 -0.1 0.1 -0.1 -0.0 -0.1 -0.3 -0.4 -0.0 -0.0 0.1 0.1 0.0 -0.0 -0.3 0.2 -0.1 0.1 0.1 -0.2 -0.3 0.1 -0.1 0.1 -0.7 0.0 0.2 -0.3 0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 0.9 0.4 0.5 0.5 0.5 0.4 0.4 0.4 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.6 0.8 0.5 0.6 0.5 0.5 0.1 0.5 0.6 0.3 0.5 0.4 0.5 0.3 0.6 0.3 0.5 0.6 0.4 0.4 0.3 0.7 0.5 -1.0 0.6 0.0 0.2 0.5
Wheeze or whistling in the chest in last year 0.0 0.0 0.4 -0.4 -0.1 0.7 -0.1 -0.2 -0.1 -0.2 -0.1 0.2 -0.3 -0.3 -0.2 -0.2 -0.2 -0.1 -0.0 -0.3 -0.0 -0.0 -0.1 -0.1 -0.2 -0.1 0.0 -0.3 -0.3 -0.2 -0.1 -0.3 -0.0 -0.1 0.1 -0.0 -0.1 0.1 -0.2 0.0 -0.1 -0.6 -0.1 -0.0 -0.2 -0.0
Number of children fathered 0.1 0.1 0.3 -0.3 -0.3 -0.4 -0.2 -0.1 -0.2 -0.4 -0.3 -0.3 -0.2 -0.4 -0.4 -0.0 -0.6 -0.6 -0.2 -0.3 -0.2 -0.2 -0.3 -0.3 -0.2 -0.3 -0.2 -0.0 -0.1 -0.2 -0.2 -0.3 -0.1 -0.2 -0.1 -0.2 -0.1 -0.2 -0.3 -0.4 -0.2 -0.6 -0.1 -0.0 -0.0 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 2.2 1.4 1.1 1.5 1.2 1.1 1.1 1.0 1.1 1.1 1.2 1.0 1.0 1.0 1.0 1.2 1.5 1.1 1.2 1.3 1.2 1.0 1.1 1.1 1.2 1.2 1.2 1.3 1.2 1.4 1.1 1.0 1.1 1.2 1.1 1.2 1.0 1.1 1.2 1.2 1.1 -1.2 1.4 1.2
Age at first live birth 0.7 1.2 3.9 -0.7 -1.1 0.1 -0.9 -1.0 -1.2 -0.5 -0.9 -0.3 -1.1 -0.6 -0.5 -1.2 -1.5 -0.9 -1.0 -1.6 -1.0 -0.7 -1.1 -1.2 -0.8 -1.1 -1.0 -1.4 -1.3 -1.1 -1.3 -1.4 -0.9 -1.3 -1.0 -1.4 -1.0 -0.9 -0.8 -1.4 -1.3 -1.0 -1.0 2.0 -0.9 -1.0
Pulse wave peak to peak time 1.0 1.1 1.9 -1.2 -1.0 -0.8 -1.0 -1.2 -1.2 -1.1 -1.1 -1.1 -1.1 -1.1 -1.1 -1.4 -0.8 -0.8 -1.0 -1.2 -1.0 -0.9 -1.0 -1.0 -0.9 -1.1 -1.1 -1.2 -1.1 -1.1 -1.0 -1.0 -1.1 -1.4 -1.0 -1.1 -1.2 -1.1 -1.1 -1.0 -1.1 -0.8 -1.1 0.9 -1.0 -1.1
Health satisfaction 1.4 1.8 3.3 -1.0 -1.3 -0.6 -1.3 -1.2 -1.1 -1.1 -1.2 -0.9 -1.2 -1.1 -1.1 -1.5 -1.4 -1.0 -1.6 -1.4 -1.2 -1.2 -1.3 -1.4 -1.3 -1.3 -1.2 -1.6 -1.6 -1.4 -1.3 -1.7 -1.4 -1.6 -1.1 -1.4 -1.2 -1.0 -1.3 -1.3 -1.4 -1.8 -1.4 1.6 -1.6 -1.2
Shortness of breath walking on level ground 0.7 0.9 1.6 0.9 1.0 1.0 1.1 1.1 1.1 0.8 1.0 0.9 1.2 1.0 0.9 1.2 0.6 0.8 0.5 0.4 1.2 1.2 1.0 0.7 0.9 1.1 1.0 1.0 0.7 1.1 0.9 1.0 0.9 0.7 1.2 0.8 1.1 1.1 0.8 0.7 0.9 0.0 0.7 -1.3 0.4 1.1
Qualifications: College or University degree 3.4 10.7 16.6 4.1 3.2 3.1 3.4 3.5 3.4 3.7 3.5 3.5 3.3 3.7 3.7 3.5 2.8 3.1 2.8 2.8 3.2 3.4 3.2 3.1 3.4 3.2 3.3 2.9 3.6 3.0 3.1 3.2 3.3 3.3 3.2 3.0 2.8 3.4 3.5 2.8 3.1 3.3 3.3 -2.4 3.6 3.3
Eye problems/disorders: None of the above 0.8 1.0 3.2 -1.0 -1.0 -1.1 -0.9 -0.9 -0.9 -1.1 -1.0 -1.2 -0.8 -1.0 -1.1 -1.1 -1.1 -0.9 -1.0 -1.4 -0.9 -1.1 -0.9 -0.8 -0.7 -0.9 -1.1 -1.2 -1.0 -0.9 -1.1 -1.0 -0.8 -1.8 -0.8 -1.1 -0.8 -0.9 -0.9 -1.2 -1.0 0.2 -0.9 0.0 -0.6 -0.9
Mouth/teeth dental problems: Loose teeth 0.2 0.3 0.7 -0.7 -0.5 -0.5 -0.6 -0.5 -0.6 -0.2 -0.4 -0.3 -0.5 -0.3 -0.2 -0.5 -0.6 -0.7 -0.5 -0.3 -0.5 -0.6 -0.5 -0.3 -0.5 -0.5 -0.5 -0.8 -0.3 -0.5 -0.5 -0.4 -0.8 -0.7 -0.5 -0.4 -0.7 -0.7 -0.2 -0.5 -0.5 -0.3 -0.7 0.9 -0.3 -0.5
Emphysema/chronic bronchitis 0.7 0.8 1.8 -1.0 -0.9 -0.9 -0.9 -1.0 -1.0 -1.0 -1.0 -1.0 -0.8 -1.0 -1.0 -1.0 -0.8 -0.8 -0.9 -0.7 -0.8 -0.9 -0.9 -1.0 -0.9 -0.9 -0.9 -0.6 -0.8 -0.8 -0.8 -0.8 -0.8 -1.1 -0.7 -0.8 -1.0 -1.1 -1.0 -0.6 -0.8 -0.6 -0.8 0.5 -1.3 -0.9
Medication for pain relief, constipation, heartburn 1.2 2.0 3.8 1.3 1.4 1.6 1.4 1.3 1.4 1.4 1.4 1.3 1.4 1.3 1.3 1.3 1.1 1.4 1.4 1.1 1.3 1.2 1.4 1.6 1.7 1.4 1.4 1.2 1.3 1.2 1.3 1.3 1.6 1.4 1.4 1.3 1.9 1.5 1.5 1.1 1.4 1.8 1.5 -1.5 1.9 1.4
Neck or shoulder pain in last month 1.0 1.4 3.0 0.5 1.3 1.1 1.3 1.3 1.1 0.9 1.1 0.7 1.3 1.0 0.9 1.1 1.6 1.5 1.2 1.3 1.3 1.0 1.3 1.2 1.2 1.3 1.1 0.9 1.0 1.1 1.5 1.1 1.3 0.9 1.1 1.4 1.0 1.1 0.9 1.3 1.3 -0.1 1.3 -1.7 0.7 1.1
Medication: Blood pressure 0.0 0.0 0.4 -0.2 -0.1 -0.1 -0.0 0.0 -0.1 -0.1 -0.0 -0.0 -0.0 -0.1 -0.1 0.1 -0.2 -0.1 -0.0 -0.2 -0.1 -0.0 -0.0 -0.1 -0.3 -0.1 0.0 -0.4 -0.1 -0.1 -0.1 -0.1 0.1 -0.0 -0.1 -0.1 0.1 0.0 -0.0 -0.3 -0.1 -0.6 0.0 0.1 0.2 0.0
Angina (self-reported) 0.7 1.0 1.8 0.9 1.0 0.7 1.0 1.0 1.0 0.8 1.0 0.9 1.0 0.9 0.8 1.0 1.1 1.1 1.1 1.0 1.1 0.9 1.0 1.0 1.0 1.0 1.0 1.1 1.1 1.1 1.1 1.0 1.0 0.8 1.0 1.1 0.8 0.8 0.9 0.9 1.1 0.4 0.9 -1.3 0.9 1.0
Migraine (self-reported) 0.1 0.2 2.2 0.0 0.2 0.1 0.3 0.3 0.3 0.4 0.4 0.1 0.3 0.4 0.4 0.3 -0.1 -0.1 0.5 0.1 0.3 -0.2 0.2 0.4 0.5 0.2 0.1 0.5 0.7 0.3 0.2 0.6 0.1 -0.3 0.4 0.1 -0.0 0.2 0.5 0.0 0.2 1.5 0.3 -0.6 0.8 0.1
Medication: Ibuprofen 0.5 0.6 1.8 -0.6 -0.8 -1.3 -0.8 -0.7 -0.7 -0.8 -0.8 -0.9 -0.7 -0.8 -0.8 -0.6 -0.5 -0.8 -0.8 -0.6 -0.8 -0.6 -0.7 -0.7 -0.8 -0.8 -0.7 -0.7 -0.6 -0.8 -0.7 -0.6 -0.9 -0.6 -0.8 -0.7 -1.0 -0.4 -0.8 -0.7 -0.7 -0.6 -0.8 0.8 -0.9 -0.8
Medication: Allopurinol 0.1 0.1 0.5 -0.4 -0.2 -0.1 -0.2 -0.4 -0.3 -0.3 -0.2 -0.5 -0.1 -0.3 -0.3 -0.2 -0.2 -0.2 -0.2 -0.4 -0.1 -0.5 -0.1 -0.4 -0.2 -0.1 -0.3 -0.5 -0.2 -0.1 -0.1 -0.2 -0.5 -0.7 -0.3 -0.2 -0.7 -0.4 -0.2 -0.2 -0.2 0.1 -0.4 -0.4 -0.6 -0.2
Medication: Omeprazole 2.4 2.9 5.2 -1.8 -1.8 -1.2 -1.8 -1.7 -1.7 -1.4 -1.6 -1.6 -1.9 -1.4 -1.4 -1.6 -2.1 -1.8 -1.8 -1.6 -1.8 -1.8 -1.8 -1.8 -1.7 -1.8 -1.8 -1.7 -1.5 -1.7 -1.7 -1.7 -2.0 -1.5 -1.7 -1.7 -1.8 -2.3 -1.5 -1.8 -1.7 -0.6 -1.9 1.8 -1.7 -1.8
Medication: Seretide 50 evohaler 0.8 0.9 3.1 0.7 0.9 0.9 0.9 1.0 0.8 1.3 1.1 1.2 1.0 1.2 1.3 1.0 0.7 0.9 0.9 0.5 1.0 0.8 0.9 0.8 0.8 0.9 0.9 0.6 1.0 1.1 0.8 1.1 0.7 0.2 0.9 0.8 0.4 0.8 1.3 0.8 0.8 1.8 0.8 -0.5 0.6 0.9
Mean time to correctly identify matches 0.1 0.2 1.0 -0.4 -0.3 -0.3 -0.3 -0.5 -0.5 -0.6 -0.5 -0.6 -0.4 -0.5 -0.5 -0.4 -0.0 -0.2 -0.3 0.1 -0.4 -0.4 -0.3 -0.4 -0.4 -0.4 -0.5 0.0 -0.3 -0.3 -0.2 -0.4 -0.2 -0.1 -0.6 -0.2 -0.3 -0.9 -0.6 0.0 -0.3 -1.0 -0.1 0.3 -0.5 -0.5
Heart disease (mother) 0.2 0.2 1.4 -0.2 -0.4 0.2 -0.4 -0.2 -0.4 -0.6 -0.5 -0.5 -0.4 -0.6 -0.7 -0.3 -0.5 -0.4 -0.4 -0.1 -0.4 -0.2 -0.4 -0.5 -0.6 -0.4 -0.3 -0.2 -0.5 -0.2 -0.2 -0.7 -0.3 0.0 -0.4 -0.2 -0.2 -0.5 -0.7 -0.4 -0.2 -1.2 -0.3 0.1 -0.6 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.4 1.7 -0.8 -0.7 -0.2 -0.7 -0.8 -0.7 -0.6 -0.7 -0.7 -0.6 -0.6 -0.6 -0.7 -0.5 -0.7 -0.5 -0.6 -0.7 -0.7 -0.7 -0.3 -0.5 -0.7 -0.7 -0.6 -0.5 -0.7 -0.7 -0.5 -0.7 -1.3 -0.8 -0.7 -0.9 -0.6 -0.5 -0.5 -0.7 -0.1 -0.6 0.6 -0.1 -0.7
Whole body fat mass 1.4 5.7 11.3 2.3 2.5 3.4 2.4 2.4 2.3 1.8 2.2 2.1 2.3 1.8 1.8 2.1 2.8 2.4 2.7 2.5 2.4 2.5 2.5 2.0 2.1 2.5 2.5 2.4 2.0 2.5 2.6 2.2 2.6 2.8 2.3 2.7 2.5 2.4 1.9 2.8 2.6 0.9 2.6 -2.9 1.7 2.4
Leg fat mass (right) 1.0 3.7 8.1 1.7 2.0 2.8 1.9 1.9 1.9 1.4 1.8 1.6 1.9 1.4 1.4 1.7 2.4 2.0 2.4 2.1 2.1 2.0 2.0 1.6 1.7 2.0 2.1 1.9 1.6 2.0 2.1 1.7 2.0 2.0 1.8 2.2 1.9 1.9 1.5 2.4 2.2 0.6 2.0 -2.5 1.2 2.0
Arm predicted mass (right) 0.8 4.0 6.2 1.9 2.2 1.4 2.1 2.0 2.0 2.0 2.1 1.8 2.3 1.9 2.0 1.9 2.3 2.0 2.1 2.1 2.2 2.3 2.1 1.8 1.8 2.2 2.2 1.5 1.9 2.0 2.1 1.8 2.1 1.9 2.1 2.2 1.3 1.7 2.0 2.5 2.2 1.5 2.0 -2.0 1.3 2.1
Pulse rate, automated reading 0.0 0.2 0.8 0.2 -0.4 -0.2 -0.2 -0.2 -0.1 -0.4 -0.3 -0.2 -0.2 -0.4 -0.3 -0.3 -0.4 -0.4 -0.6 -0.6 -0.4 -0.1 -0.3 -0.8 -0.7 -0.3 -0.2 -0.4 -0.5 -0.3 -0.5 -0.6 0.0 -0.1 -0.3 -0.4 -0.4 -0.3 -0.3 -0.4 -0.4 -0.7 -0.1 0.2 -0.9 -0.2
Alcohol intake frequency. 0.0 0.1 0.6 -0.2 -0.2 -0.7 -0.2 -0.4 -0.1 0.1 -0.1 0.0 -0.1 0.1 0.1 -0.2 -0.3 -0.1 -0.0 -0.0 -0.2 -0.5 -0.3 -0.2 -0.6 -0.2 -0.3 -0.2 -0.0 -0.1 -0.3 0.0 -0.2 -0.4 -0.1 -0.2 -0.0 -0.6 0.0 -0.1 -0.2 0.8 -0.2 0.6 -0.5 -0.2
Comparative height size at age 10 0.5 2.7 5.2 2.0 1.6 2.3 1.6 1.7 1.6 1.7 1.7 1.8 1.5 1.6 1.7 1.3 1.4 1.4 1.7 1.3 1.6 1.9 1.6 1.2 1.5 1.6 1.8 1.5 1.5 1.7 1.6 1.3 1.7 2.2 1.5 1.6 1.7 1.4 1.7 1.6 1.6 2.1 1.5 -1.2 1.3 1.7
Number of full sisters 1.4 1.7 2.4 1.1 1.3 1.1 1.3 1.3 1.4 1.5 1.4 1.5 1.3 1.4 1.5 1.3 1.3 1.4 1.3 1.4 1.3 1.3 1.3 1.5 1.1 1.3 1.4 1.4 1.5 1.1 1.3 1.2 1.2 1.2 1.3 1.4 1.3 1.5 1.4 1.4 1.3 0.5 1.3 -0.8 1.4 1.3
Suffer from ‘nerves’ 0.0 0.0 0.5 -0.2 0.0 -0.7 -0.0 0.1 -0.0 -0.0 0.0 -0.1 0.1 -0.0 0.0 0.2 -0.0 0.0 -0.3 -0.2 0.0 -0.1 -0.0 -0.2 -0.3 0.0 -0.1 0.2 0.2 0.1 -0.1 0.1 0.1 -0.1 0.0 -0.0 -0.2 -0.2 0.1 0.0 -0.0 0.4 -0.1 -0.3 -0.7 0.0
Overall health rating 0.8 1.7 8.9 -1.6 -1.1 -1.1 -1.3 -1.2 -1.1 -1.2 -1.2 -1.0 -1.2 -1.3 -1.2 -1.4 -0.7 -1.0 -1.3 -1.0 -1.2 -0.9 -1.2 -1.4 -1.9 -1.2 -1.0 -1.2 -1.4 -1.2 -1.1 -1.5 -1.3 -0.8 -1.2 -1.1 -0.9 -1.3 -1.3 -0.9 -1.1 -3.0 -1.3 1.6 -2.1 -1.1
Chest pain or discomfort 0.1 0.1 0.6 -0.5 -0.2 -0.2 -0.4 -0.2 -0.3 -0.3 -0.3 -0.2 -0.4 -0.3 -0.3 -0.2 0.1 -0.1 -0.4 -0.1 -0.3 -0.3 -0.2 -0.5 -0.4 -0.3 -0.2 -0.3 -0.2 -0.5 -0.2 -0.4 -0.3 0.1 -0.4 -0.2 -0.7 -0.4 -0.3 0.1 -0.2 -0.6 -0.5 0.4 -0.8 -0.3
Had major operations 1.6 1.9 3.6 -1.5 -1.4 -0.8 -1.4 -1.4 -1.4 -1.3 -1.3 -0.9 -1.5 -1.5 -1.3 -1.5 -1.5 -1.5 -1.3 -1.2 -1.5 -1.2 -1.4 -1.2 -1.6 -1.4 -1.2 -1.6 -1.5 -1.6 -1.5 -1.9 -1.1 -0.8 -1.2 -1.3 -1.0 -1.4 -1.3 -1.4 -1.3 -1.9 -1.3 1.7 -1.1 -1.3
Age at last live birth 0.3 0.4 3.1 1.0 0.6 1.8 0.7 0.5 0.5 0.8 0.6 1.1 0.4 0.8 0.8 0.4 0.5 0.7 0.5 0.3 0.6 0.8 0.6 0.6 0.7 0.5 0.7 0.4 0.3 0.3 0.4 0.3 0.9 0.4 0.6 0.4 0.7 0.8 0.6 0.5 0.4 0.1 0.7 0.2 0.8 0.6
Family relationship satisfaction 0.2 0.2 0.7 0.3 0.3 0.7 0.2 0.1 0.5 0.7 0.5 0.8 0.2 0.6 0.7 0.2 0.1 0.3 0.5 0.2 0.3 0.4 0.3 0.6 0.2 0.3 0.5 0.5 0.4 0.1 0.2 0.2 0.1 0.1 0.6 0.2 0.5 0.6 0.6 0.4 0.2 0.6 0.1 0.5 0.8 0.4
Leg pain on walking 0.3 0.4 2.0 0.4 0.6 0.6 0.6 0.7 0.6 0.2 0.5 0.1 0.8 0.3 0.2 0.7 0.5 0.4 0.5 0.8 0.8 0.5 0.7 0.7 0.6 0.7 0.5 0.6 0.7 0.7 0.8 0.8 0.5 0.4 0.6 0.8 0.5 0.5 0.3 0.7 0.8 0.1 0.5 -1.4 0.2 0.6
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.1 0.7 -0.5 -0.0 -0.4 -0.1 -0.2 -0.2 -0.2 -0.2 -0.1 -0.1 -0.2 -0.2 -0.2 0.3 0.1 -0.1 0.5 -0.1 0.1 -0.0 0.2 -0.2 -0.0 0.1 0.1 -0.3 -0.1 0.1 -0.0 0.1 0.5 -0.0 0.1 0.5 -0.2 -0.2 0.2 0.1 -0.8 -0.1 0.0 -0.0 -0.1
Commuting to job workplace: Car/motor vehicle 0.9 1.1 2.2 1.1 1.0 0.9 0.9 0.9 0.9 1.2 1.0 1.2 0.9 1.1 1.1 0.9 1.0 1.2 1.1 1.0 1.0 1.0 1.0 1.2 1.3 0.9 1.0 1.4 0.9 0.9 0.9 1.1 0.9 0.9 1.2 0.9 1.4 1.3 1.1 0.9 0.9 0.6 1.0 -0.6 1.5 0.9
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.3 -0.1 0.3 0.2 0.4 0.3 0.3 0.3 0.4 -0.1 0.5 0.3 0.3 0.5 0.1 0.1 0.3 0.0 0.5 0.2 0.4 0.1 0.3 0.4 0.2 -0.2 0.4 0.4 0.4 0.3 0.1 -0.1 0.1 0.3 -0.4 -0.0 0.3 0.1 0.3 -0.1 0.0 -0.4 -0.2 0.3
Medication: Aspirin 0.4 0.6 1.6 -0.6 -0.7 -0.6 -0.6 -0.5 -0.8 -0.5 -0.6 -0.3 -0.7 -0.6 -0.5 -0.6 -0.6 -0.7 -0.9 -1.1 -0.6 -0.5 -0.7 -1.0 -1.1 -0.6 -0.6 -0.9 -0.8 -0.5 -0.8 -0.8 -0.6 -1.0 -0.6 -0.9 -1.1 -1.0 -0.6 -0.7 -0.8 -1.0 -0.8 0.9 -1.2 -0.5
Supplements: Vitamin C 1.7 2.0 3.2 -1.3 -1.5 -1.3 -1.5 -1.4 -1.3 -1.1 -1.3 -1.1 -1.5 -1.2 -1.1 -1.4 -1.7 -1.3 -1.5 -1.4 -1.6 -1.6 -1.5 -1.6 -1.3 -1.5 -1.5 -1.3 -1.5 -1.5 -1.5 -1.7 -1.3 -1.6 -1.3 -1.4 -1.5 -1.1 -1.2 -1.4 -1.5 -1.5 -1.3 1.8 -1.4 -1.5
Knee pain experienced in last month 2.9 4.5 6.4 2.1 2.2 2.4 2.1 2.1 2.0 2.1 2.1 2.2 2.0 2.1 2.1 2.1 2.4 2.4 2.2 2.4 2.1 2.0 2.2 2.2 2.0 2.2 2.1 2.4 2.0 2.2 2.4 2.0 1.9 2.2 2.1 2.4 2.1 2.0 2.0 2.5 2.3 0.9 2.0 -1.8 1.6 2.1
Hypertension (Self-reported) 1.5 4.1 7.6 -2.2 -2.0 -2.0 -1.9 -1.8 -2.1 -2.1 -2.0 -1.9 -1.9 -2.0 -2.1 -1.8 -1.8 -1.9 -2.1 -2.1 -1.9 -1.8 -1.9 -2.2 -2.4 -1.9 -1.9 -2.1 -2.0 -2.0 -2.0 -2.0 -1.8 -2.1 -1.9 -2.1 -1.9 -2.2 -2.1 -2.1 -2.0 -2.8 -1.9 1.4 -2.4 -1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.1 2.5 3.6 -1.6 -1.6 -1.8 -1.6 -1.6 -1.6 -1.4 -1.6 -1.7 -1.6 -1.4 -1.4 -1.5 -1.6 -1.7 -1.8 -1.2 -1.6 -1.5 -1.6 -1.6 -1.6 -1.6 -1.6 -1.8 -1.3 -1.6 -1.4 -1.3 -1.8 -0.9 -1.9 -1.5 -1.9 -1.8 -1.6 -1.4 -1.5 -1.3 -1.6 1.7 -1.8 -1.7
Illnesses of father: Heart disease 0.1 0.1 0.3 -0.2 -0.3 0.6 -0.3 -0.3 -0.3 -0.2 -0.2 -0.3 -0.3 -0.3 -0.2 -0.5 -0.3 0.1 0.2 0.0 -0.3 -0.5 -0.3 -0.3 -0.0 -0.2 -0.3 0.2 -0.4 -0.1 -0.1 -0.3 -0.2 -0.5 -0.3 -0.0 -0.3 -0.2 -0.2 0.1 -0.1 -0.4 -0.1 0.4 -0.5 -0.3
Illnesses of siblings: Diabetes 0.3 0.3 1.1 0.1 0.5 1.1 0.5 0.5 0.5 0.2 0.4 0.1 0.4 0.3 0.2 0.4 0.6 0.7 0.7 0.7 0.5 0.4 0.5 0.7 0.6 0.5 0.5 0.7 0.4 0.6 0.7 0.5 0.7 0.9 0.4 0.7 0.8 0.3 0.3 0.7 0.7 0.2 0.7 -1.0 0.4 0.5
Smoking status: Previous 1.5 2.3 3.2 1.5 1.6 1.5 1.6 1.7 1.3 1.6 1.6 1.6 1.6 1.6 1.6 1.6 1.7 1.6 1.7 1.4 1.6 1.6 1.6 1.5 1.6 1.6 1.6 1.4 1.5 1.4 1.5 1.2 1.6 1.1 1.8 1.4 1.3 1.4 1.6 1.3 1.5 1.0 1.6 -1.4 1.6 1.6
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 2.3 1.4 1.1 1.1 1.1 1.2 1.1 1.3 1.1 1.5 1.2 1.2 1.3 0.9 0.9 1.3 0.8 0.5 1.1 1.5 1.1 0.6 0.9 1.0 1.2 0.9 0.6 1.1 0.9 0.6 1.1 1.2 1.1 0.8 0.9 1.3 1.0 0.8 0.9 -0.4 0.9 -0.1 0.5 1.2
Whole body fat-free mass 1.1 6.4 8.5 2.6 2.8 1.7 2.7 2.7 2.6 2.6 2.7 2.5 2.9 2.6 2.7 2.5 2.6 2.6 2.5 2.5 2.7 2.9 2.6 2.2 2.3 2.7 2.8 2.0 2.5 2.5 2.6 2.3 2.6 2.5 2.8 2.6 1.9 2.3 2.6 2.9 2.7 2.0 2.5 -2.4 1.7 2.7
Leg fat-free mass (right) 1.8 9.8 12.7 3.2 3.4 2.4 3.3 3.2 3.2 3.1 3.2 3.1 3.5 3.0 3.2 3.0 3.4 3.3 3.1 3.1 3.3 3.5 3.2 2.8 2.9 3.3 3.4 2.7 3.0 3.2 3.3 2.9 3.3 3.3 3.4 3.3 2.6 3.0 3.1 3.6 3.3 2.3 3.1 -3.0 2.2 3.3
Arm fat percentage (left) 1.7 6.7 12.9 2.4 2.6 3.6 2.6 2.6 2.6 1.9 2.3 2.2 2.4 2.0 2.0 2.4 3.0 2.8 2.9 2.8 2.6 2.6 2.7 2.2 2.3 2.7 2.7 2.8 2.2 2.7 2.8 2.5 2.6 3.0 2.5 2.9 2.9 2.7 2.1 2.9 2.8 1.0 2.7 -3.2 2.0 2.6
Average weekly red wine intake 0.3 0.5 2.2 0.5 0.6 0.7 0.6 0.5 0.5 1.2 0.9 1.0 0.5 1.0 1.1 0.4 0.4 0.8 0.7 0.2 0.5 0.5 0.5 0.6 0.8 0.6 0.5 0.3 0.9 0.6 0.4 0.6 0.6 0.3 0.7 0.3 0.7 0.4 1.1 0.3 0.4 1.5 0.6 -0.1 1.0 0.5
Handedness (chirality/laterality): Left-handed 2.1 2.5 5.5 1.8 1.5 1.5 1.6 1.5 1.4 2.2 1.7 2.3 1.4 2.0 2.2 1.4 1.5 1.8 1.5 0.9 1.5 1.9 1.5 1.5 1.3 1.4 1.8 1.3 1.3 1.4 1.3 1.6 1.6 1.4 1.6 1.2 1.4 2.2 1.9 1.4 1.2 0.7 1.5 0.1 1.6 1.6
Mood swings 0.4 0.6 1.2 -0.8 -0.8 -0.9 -0.9 -0.8 -0.7 -0.9 -0.9 -0.8 -0.8 -0.8 -0.8 -0.9 -0.5 -0.7 -0.8 -0.5 -0.7 -0.8 -0.8 -0.7 -1.1 -0.8 -0.7 -1.1 -0.8 -0.9 -0.7 -0.9 -0.9 -0.9 -0.8 -0.7 -1.0 -0.6 -0.9 -0.5 -0.7 -0.8 -0.7 0.8 -0.9 -0.8
Loneliness, isolation 2.3 3.2 4.3 -2.0 -1.8 -1.7 -1.9 -1.9 -1.8 -1.8 -1.8 -1.8 -1.8 -1.8 -1.8 -1.8 -1.8 -1.8 -1.9 -2.0 -1.7 -1.9 -1.8 -1.7 -2.0 -1.8 -1.9 -1.8 -1.7 -1.7 -1.8 -1.7 -1.8 -2.1 -1.7 -1.9 -1.9 -2.0 -1.7 -1.7 -1.9 -0.9 -1.9 1.3 -1.9 -1.8
Long-standing illness, disability or infirmity 0.0 0.1 0.5 -0.4 0.0 -0.1 -0.1 -0.2 -0.2 -0.1 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 0.2 0.0 -0.4 0.1 -0.1 -0.2 -0.1 -0.0 -0.3 -0.1 -0.2 -0.2 -0.2 -0.3 -0.1 -0.3 -0.1 -0.2 0.0 -0.0 -0.0 -0.4 -0.1 0.3 -0.1 -0.5 -0.2 0.0 -0.7 -0.1
Ever had bowel cancer screening 0.3 0.3 1.2 -0.2 0.6 0.3 0.6 0.4 0.5 0.0 0.4 0.2 0.6 0.1 0.1 0.5 0.6 0.4 0.5 0.8 0.5 0.5 0.6 0.5 0.6 0.6 0.5 0.6 0.1 0.6 0.7 0.1 0.8 0.7 0.6 0.8 1.0 0.1 0.2 0.7 0.8 -0.6 0.8 -1.1 0.1 0.6
Diabetes diagnosed by doctor 0.8 1.3 2.0 0.7 1.2 1.2 1.2 1.1 1.1 1.1 1.1 1.0 1.0 1.1 1.1 1.1 1.3 1.4 1.4 1.0 1.1 1.2 1.2 1.1 1.2 1.1 1.2 1.0 1.2 1.1 1.2 1.2 1.4 1.3 1.1 1.1 1.4 1.1 1.1 1.3 1.1 0.8 1.4 -1.2 1.2 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.0 0.0 0.3 -0.1 0.0 0.6 -0.1 -0.1 -0.0 -0.2 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 0.0 -0.1 -0.6 0.2 0.0 -0.2 -0.1 0.3 0.1 0.0 -0.0 -0.2 -0.2 -0.2 0.1 0.1 -0.1 -0.2 0.0 0.1 -0.2 0.1 -0.0 0.2 0.1 0.2 -0.1 -0.5 -0.2 -0.0
Friendships satisfaction 0.1 0.1 1.0 0.5 -0.0 0.2 -0.0 0.0 0.1 0.5 0.2 0.7 -0.1 0.4 0.4 -0.0 0.1 0.2 0.2 0.4 0.0 0.2 0.0 0.2 -0.0 -0.0 0.3 0.6 0.2 0.0 0.1 0.1 -0.2 0.3 0.3 0.1 0.2 0.6 0.2 0.1 0.0 -0.2 -0.1 1.0 0.4 0.1
Qualifications: nursing, teaching 3.1 4.9 7.5 2.6 2.3 1.1 2.2 2.3 2.1 2.7 2.4 2.3 2.3 2.6 2.7 2.3 2.3 2.2 2.3 2.2 2.1 2.4 2.2 2.1 2.3 2.2 2.2 2.1 2.7 2.1 2.2 2.1 2.1 2.6 2.2 2.0 1.8 1.8 2.4 2.3 2.1 1.8 2.1 -1.0 2.4 2.1
Commuting to job workplace: Walk 0.2 0.2 0.5 0.2 0.4 0.1 0.5 0.5 0.4 0.6 0.5 0.7 0.5 0.5 0.6 0.3 0.4 0.4 0.6 0.1 0.4 0.7 0.4 0.3 0.3 0.4 0.5 0.2 0.3 0.4 0.3 0.1 0.7 0.2 0.5 0.2 0.4 0.5 0.5 0.2 0.3 -0.2 0.5 0.0 0.3 0.5
Eye problems/disorders: Cataract 0.0 0.0 0.5 0.1 0.1 0.6 0.1 -0.0 0.1 0.2 0.1 0.1 -0.1 0.2 0.2 0.1 -0.1 0.1 0.5 0.2 0.2 -0.1 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.1 0.3 -0.0 0.2 0.1 0.1 -0.2 0.1 0.2 0.2 0.1 0.7 0.1 -0.0 0.4 -0.0
Mouth/teeth dental problems: Mouth ulcers 2.7 4.3 6.9 -2.5 -2.0 -2.6 -2.2 -2.2 -2.3 -2.2 -2.1 -2.1 -2.1 -2.1 -2.2 -2.1 -1.6 -1.9 -2.2 -1.5 -2.2 -2.2 -2.1 -1.8 -2.3 -2.0 -2.1 -2.1 -2.1 -2.1 -2.0 -2.2 -1.9 -1.8 -1.9 -1.9 -1.5 -2.3 -2.1 -2.0 -1.9 -2.0 -2.0 1.8 -2.2 -2.1
Medication for cholesterol 1.9 2.9 4.8 1.7 1.6 1.6 1.6 1.5 1.7 1.6 1.6 1.6 1.6 1.6 1.6 1.6 1.5 1.7 1.9 1.9 1.6 1.5 1.6 2.1 1.9 1.6 1.6 1.7 1.7 1.7 1.7 1.7 1.4 1.8 1.6 1.8 2.0 1.7 1.6 1.6 1.7 2.2 1.7 -1.2 2.2 1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 0.7 -0.6 -0.6 0.1 -0.6 -0.6 -0.5 -0.5 -0.5 -0.1 -0.7 -0.5 -0.5 -0.5 -0.6 -0.6 -0.4 -0.4 -0.6 -0.5 -0.5 -0.6 -0.6 -0.6 -0.4 -0.5 -0.7 -0.6 -0.7 -0.6 -0.4 -0.5 -0.5 -0.5 -0.4 0.0 -0.4 -0.5 -0.5 -0.3 -0.5 0.8 -0.2 -0.5
Back pain experienced in last month 0.3 0.4 1.5 0.3 0.6 0.8 0.5 0.7 0.5 0.8 0.7 1.0 0.6 0.7 0.8 0.4 0.6 0.6 0.3 0.5 0.6 0.9 0.5 0.5 0.2 0.6 0.8 0.4 0.4 0.6 0.5 0.2 0.6 0.6 0.9 0.5 1.2 0.5 0.6 0.5 0.6 -1.0 0.4 -0.0 0.2 0.7
Mineral and other dietary supplements 0.2 0.3 1.2 0.4 0.5 0.5 0.6 0.4 0.5 0.2 0.4 0.0 0.7 0.3 0.3 0.4 0.5 0.4 0.5 0.4 0.6 0.5 0.6 0.4 0.5 0.5 0.4 0.1 0.6 0.5 0.5 0.8 0.7 0.3 0.4 0.5 0.5 0.5 0.4 0.6 0.5 1.1 0.6 -1.1 0.3 0.5
Breast cancer (self-reported) 0.3 0.4 1.0 -0.6 -0.5 0.3 -0.5 -0.7 -0.6 -0.2 -0.5 -0.4 -0.7 -0.2 -0.2 -0.8 -0.6 -0.2 -0.6 -0.6 -0.6 -0.6 -0.5 -0.6 -0.3 -0.6 -0.7 -0.6 -0.6 -0.8 -0.5 -1.0 -0.9 -0.8 -0.6 -0.7 -0.5 -0.9 -0.5 -0.4 -0.7 -0.7 -0.8 0.9 -0.5 -0.7
Asthma (self-reported) 1.1 2.2 4.4 1.3 1.5 2.1 1.5 1.6 1.4 1.5 1.5 1.5 1.4 1.4 1.5 1.6 1.3 1.3 1.2 1.7 1.5 1.5 1.5 1.5 1.5 1.5 1.5 1.1 1.6 1.4 1.7 1.5 1.3 1.6 1.4 1.7 0.9 1.5 1.5 1.8 1.7 1.0 1.5 -1.4 1.0 1.5
Osteoporosis (self-reported) 1.9 2.4 3.3 -1.1 -1.5 -0.9 -1.6 -1.5 -1.4 -1.5 -1.6 -1.4 -1.6 -1.3 -1.5 -1.5 -1.5 -1.4 -1.6 -1.4 -1.5 -1.5 -1.5 -1.8 -1.8 -1.6 -1.6 -1.6 -1.5 -1.4 -1.5 -1.3 -1.8 -1.6 -1.8 -1.6 -1.7 -1.3 -1.6 -1.6 -1.6 -1.7 -1.7 1.7 -1.6 -1.6
Osteoarthritis (self-reported) 0.4 0.5 0.9 0.7 0.8 0.6 0.7 0.6 0.8 0.8 0.8 0.7 0.8 0.8 0.8 0.8 0.6 0.9 0.6 0.5 0.8 0.6 0.8 0.5 0.7 0.8 0.6 0.8 0.7 0.8 0.7 0.9 0.7 0.4 0.6 0.6 0.2 0.5 0.8 0.8 0.7 0.9 0.5 -0.8 0.5 0.7
Medication: Aspirin 0.6 0.8 2.4 -0.8 -0.8 -0.9 -0.8 -0.7 -0.9 -0.7 -0.8 -0.5 -0.7 -0.8 -0.6 -0.7 -0.7 -0.8 -0.9 -1.1 -0.7 -0.5 -0.8 -1.1 -1.3 -0.8 -0.7 -1.0 -0.9 -0.7 -0.9 -1.0 -0.7 -0.9 -0.8 -0.9 -1.2 -1.1 -0.8 -0.7 -0.9 -1.6 -0.9 1.1 -1.5 -0.6
Medication: Gliclazide 1.8 2.0 3.7 1.0 1.4 1.2 1.5 1.4 1.4 1.2 1.3 1.1 1.4 1.2 1.2 1.4 1.5 1.6 1.6 1.4 1.3 1.3 1.4 1.4 1.4 1.4 1.4 1.4 1.5 1.5 1.5 1.6 1.5 1.6 1.4 1.5 1.9 1.3 1.3 1.4 1.5 1.2 1.6 -1.6 1.3 1.4
Illnesses of father: None of the above (group 1) 1.1 1.3 3.0 -1.4 -1.1 -1.1 -1.1 -1.1 -1.1 -0.9 -1.0 -1.1 -1.0 -0.9 -1.0 -0.9 -1.4 -1.3 -1.4 -1.4 -1.1 -1.0 -1.0 -1.1 -1.1 -1.1 -1.2 -1.7 -0.8 -1.3 -1.2 -1.0 -1.2 -1.0 -1.2 -1.3 -1.2 -1.3 -1.0 -1.6 -1.3 -0.1 -1.4 0.8 -0.8 -1.1
Smoking status: Current 1.4 2.2 3.5 -1.6 -1.5 -1.3 -1.5 -1.5 -1.6 -1.5 -1.5 -1.5 -1.6 -1.5 -1.4 -1.5 -1.7 -1.7 -1.5 -1.6 -1.4 -1.7 -1.5 -1.3 -1.3 -1.5 -1.7 -1.4 -1.5 -1.4 -1.5 -1.2 -1.4 -1.8 -1.4 -1.5 -1.9 -1.6 -1.4 -1.4 -1.5 -0.9 -1.5 0.9 -1.5 -1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.6 1.0 0.7 0.9 0.7 0.7 0.7 0.9 0.8 1.0 0.7 0.8 0.9 0.8 0.6 0.7 1.0 0.8 0.7 1.0 0.8 0.6 0.6 0.7 0.9 0.9 0.7 0.7 0.8 0.7 0.6 0.8 0.8 0.8 1.0 1.3 0.8 0.7 0.8 -0.1 0.7 -0.1 1.1 0.8
Whole body water mass 1.2 6.8 9.0 2.6 2.9 1.8 2.8 2.7 2.7 2.7 2.8 2.5 3.0 2.6 2.8 2.5 2.7 2.6 2.5 2.6 2.8 2.9 2.6 2.3 2.4 2.8 2.8 2.0 2.6 2.6 2.7 2.4 2.7 2.6 2.8 2.7 1.9 2.4 2.7 3.0 2.7 2.0 2.6 -2.5 1.8 2.8
Leg predicted mass (right) 1.8 9.7 12.7 3.2 3.4 2.4 3.3 3.2 3.3 3.1 3.2 3.0 3.4 3.0 3.1 3.0 3.4 3.2 3.1 3.1 3.3 3.4 3.2 2.8 2.8 3.3 3.4 2.7 3.0 3.2 3.3 2.9 3.3 3.2 3.4 3.3 2.6 3.0 3.1 3.6 3.3 2.3 3.1 -3.0 2.2 3.3
Arm fat mass (left) 1.5 6.3 10.2 2.4 2.6 3.1 2.6 2.6 2.6 1.9 2.3 2.1 2.5 2.0 2.0 2.3 2.9 2.6 2.8 2.7 2.6 2.6 2.6 2.1 2.3 2.7 2.7 2.6 2.2 2.6 2.8 2.4 2.6 2.8 2.5 2.8 2.5 2.5 2.1 2.9 2.8 1.2 2.6 -3.2 1.8 2.6
Number of self-reported non-cancer illnesses 0.6 1.1 6.9 -1.3 -0.8 -0.5 -0.9 -0.8 -1.0 -1.0 -0.9 -0.7 -0.9 -0.9 -0.9 -0.9 -0.6 -0.8 -1.1 -0.7 -0.8 -0.8 -0.8 -1.1 -1.4 -0.8 -0.8 -1.2 -1.2 -0.9 -0.8 -1.2 -0.8 -0.9 -0.9 -0.8 -1.0 -1.1 -1.0 -0.7 -0.8 -2.6 -0.9 1.0 -1.7 -0.8
Average weekly champagne plus white wine intake 0.4 0.6 4.2 0.8 0.7 0.8 0.7 0.8 0.9 0.8 0.8 0.4 0.7 0.9 0.8 0.8 0.4 0.5 0.5 0.6 0.7 0.6 0.8 0.7 1.0 0.7 0.7 0.4 1.0 0.7 0.8 0.9 0.6 0.8 0.5 0.7 0.1 0.6 0.9 0.6 0.7 2.1 0.7 -0.8 0.9 0.6
Miserableness 0.2 0.3 1.6 0.2 0.5 -0.4 0.4 0.4 0.6 0.5 0.5 0.1 0.5 0.5 0.5 0.5 0.5 0.4 0.3 0.6 0.5 0.1 0.5 0.7 0.5 0.5 0.3 0.4 0.7 0.5 0.6 0.7 0.1 -0.1 0.5 0.5 0.4 0.2 0.6 0.6 0.5 1.3 0.3 -0.8 0.5 0.3
Guilty feelings 0.1 0.1 1.7 -0.0 0.1 -0.5 0.2 0.3 0.1 -0.3 0.1 -0.4 0.3 -0.2 -0.3 0.4 0.1 -0.2 0.2 0.3 0.3 -0.1 0.2 -0.0 0.3 0.3 0.0 0.2 0.3 0.3 0.4 -0.0 0.2 -0.1 0.3 0.4 -0.2 -0.2 -0.1 0.1 0.4 0.3 0.2 -1.3 -0.1 0.2
Wears glasses or contact lenses 0.4 0.4 2.1 -0.9 -0.6 -1.4 -0.6 -0.7 -0.6 -0.8 -0.6 -1.0 -0.4 -0.6 -0.8 -0.5 -0.6 -0.7 -0.7 -0.3 -0.6 -0.9 -0.7 -0.3 -0.6 -0.6 -0.8 -0.5 -0.3 -0.5 -0.6 -0.3 -0.7 -0.6 -0.7 -0.6 -0.6 -1.2 -0.7 -0.6 -0.6 0.5 -0.6 -0.0 -0.5 -0.7
Ever taken oral contraceptive pill 4.9 5.5 6.9 2.2 2.5 2.2 2.5 2.3 2.5 2.4 2.4 2.2 2.4 2.4 2.4 2.5 2.1 2.5 2.4 1.8 2.5 2.3 2.5 2.2 2.6 2.4 2.3 2.3 2.5 2.5 2.3 2.4 2.4 2.1 2.3 2.1 2.1 2.3 2.4 2.2 2.2 2.0 2.4 -2.5 2.6 2.4
Hearing aid user 0.6 0.6 3.1 0.9 0.6 0.1 0.6 0.6 0.6 0.7 0.7 0.6 0.6 0.7 0.7 0.7 0.8 0.8 0.8 1.4 0.5 0.4 0.6 1.1 1.1 0.6 0.6 1.1 1.1 0.6 0.9 0.8 0.5 0.8 0.6 0.9 0.4 0.1 0.7 0.9 0.8 1.8 0.7 -0.6 1.1 0.5
Mother’s age at death 0.3 0.4 1.0 -0.6 -0.6 -1.0 -0.6 -0.5 -0.6 -0.6 -0.5 -0.6 -0.4 -0.6 -0.6 -0.4 -0.6 -0.6 -0.6 -0.5 -0.6 -0.8 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.5 -0.8 -0.4 -0.5 -0.8 -0.7 -0.5 -0.6 -0.5 0.1 -0.7 0.2 -0.6 -0.5
Financial situation satisfaction 2.7 3.3 7.5 -1.4 -1.9 -1.8 -1.9 -1.8 -1.6 -1.9 -1.9 -1.5 -1.8 -1.9 -1.9 -1.9 -1.6 -1.6 -2.0 -1.6 -1.9 -1.5 -1.9 -1.9 -2.1 -1.9 -1.6 -1.7 -1.9 -1.9 -1.8 -2.1 -2.0 -1.6 -1.7 -1.8 -1.6 -1.2 -2.0 -1.8 -1.8 -2.7 -1.9 1.9 -2.1 -1.7
Tinnitus: Yes, now most or all of the time 0.0 0.1 0.5 -0.0 -0.0 0.3 -0.0 -0.2 -0.1 0.5 0.1 0.5 -0.1 0.3 0.4 -0.3 -0.2 0.3 0.3 -0.1 -0.1 -0.1 0.0 0.2 0.1 -0.1 -0.0 -0.0 0.0 -0.0 -0.1 0.1 -0.0 -0.5 0.0 -0.1 -0.1 -0.0 0.3 -0.1 -0.1 0.0 0.0 0.7 0.3 -0.1
Commuting to job workplace: Public transport 0.1 0.2 0.9 -0.6 -0.3 -0.1 -0.2 -0.0 -0.3 -0.6 -0.3 -0.7 -0.1 -0.5 -0.5 -0.3 -0.3 -0.5 -0.4 -0.3 -0.2 -0.5 -0.3 -0.4 -0.5 -0.2 -0.4 -0.7 -0.1 -0.1 -0.2 -0.2 -0.2 -0.5 -0.5 -0.2 -0.5 -0.5 -0.3 -0.3 -0.2 -0.2 -0.3 -0.6 -1.0 -0.3
Eye problems/disorders: Glaucoma 0.0 0.0 0.4 -0.0 -0.0 -0.1 0.0 -0.0 0.2 0.3 0.1 0.1 0.0 0.2 0.3 0.0 -0.2 -0.1 -0.2 -0.2 0.0 0.1 -0.0 -0.1 -0.3 -0.0 0.1 -0.3 0.3 0.0 -0.1 0.4 -0.5 0.1 -0.4 -0.1 -0.1 0.3 0.2 -0.2 -0.1 -0.2 -0.2 0.6 -0.3 -0.0
Medication: Blood pressure 1.2 2.2 5.2 -1.7 -1.4 -1.4 -1.4 -1.4 -1.6 -1.6 -1.6 -1.4 -1.5 -1.5 -1.6 -1.5 -1.1 -1.3 -1.5 -1.2 -1.4 -1.3 -1.4 -1.6 -1.8 -1.4 -1.4 -1.4 -1.4 -1.5 -1.4 -1.4 -1.3 -1.4 -1.4 -1.4 -1.4 -1.6 -1.7 -1.2 -1.4 -2.3 -1.4 1.1 -1.9 -1.4
Pain type(s) experienced in last month: Hip pain 1.4 1.8 2.7 1.1 1.4 1.6 1.4 1.2 1.4 1.5 1.4 1.3 1.2 1.5 1.5 1.3 1.2 1.4 1.6 1.1 1.4 1.2 1.4 1.2 1.6 1.3 1.2 1.6 1.5 1.4 1.4 1.4 1.1 1.0 1.3 1.2 1.6 1.1 1.4 1.2 1.3 1.2 1.2 -1.1 1.6 1.2
Supplements: Fish oil (including cod liver oil) 0.1 0.2 0.6 -0.3 -0.4 -0.8 -0.5 -0.4 -0.4 -0.3 -0.4 -0.4 -0.5 -0.4 -0.4 -0.4 -0.5 -0.4 -0.3 -0.3 -0.4 -0.5 -0.4 -0.4 -0.2 -0.5 -0.5 0.0 -0.3 -0.4 -0.4 -0.6 -0.6 -0.4 -0.4 -0.4 -0.5 -0.6 -0.4 -0.5 -0.4 -0.2 -0.4 0.4 0.0 -0.5
High cholesterol (Self-reported) 0.2 0.3 1.0 -0.0 0.6 0.3 0.9 0.9 0.6 0.4 0.7 0.5 0.8 0.5 0.5 1.0 0.3 0.3 0.6 -0.3 0.8 0.8 0.7 0.1 -0.0 0.8 0.6 0.2 0.5 0.9 0.4 0.3 0.8 0.3 0.6 0.4 0.4 -0.0 0.5 0.2 0.5 -0.3 0.7 -1.0 -0.2 0.8
Medication: Bendroflumethiazide 1.4 2.1 3.9 -1.6 -1.4 -1.2 -1.4 -1.4 -1.6 -1.5 -1.5 -1.4 -1.4 -1.4 -1.4 -1.5 -1.2 -1.4 -1.4 -1.2 -1.5 -1.3 -1.4 -1.4 -1.6 -1.4 -1.4 -1.8 -1.4 -1.5 -1.3 -1.4 -1.4 -1.3 -1.5 -1.4 -1.3 -1.6 -1.5 -1.2 -1.4 -2.0 -1.3 1.4 -1.6 -1.4
Medication: Paracetamol 0.3 0.4 1.0 0.5 0.7 0.5 0.6 0.5 0.7 0.6 0.6 0.7 0.5 0.5 0.6 0.7 1.0 0.8 0.7 0.9 0.7 0.9 0.7 0.6 0.4 0.6 0.7 0.8 0.5 0.7 0.8 0.3 0.4 1.0 0.6 0.8 0.6 0.3 0.4 0.8 0.7 -0.5 0.7 -0.3 0.4 0.7
Medication: Lisinopril 0.2 0.2 0.5 -0.6 -0.5 -0.3 -0.5 -0.3 -0.4 -0.3 -0.4 -0.1 -0.5 -0.3 -0.3 -0.2 -0.4 -0.4 -0.6 -0.3 -0.5 -0.4 -0.4 -0.2 -0.6 -0.5 -0.3 -0.6 -0.7 -0.6 -0.5 -0.5 -0.3 -0.0 -0.4 -0.4 -0.5 -0.3 -0.4 -0.5 -0.4 -0.7 -0.4 0.7 -0.4 -0.4
Medication: Atorvastatin 0.0 0.1 0.6 0.1 0.2 -0.5 0.3 0.3 0.2 0.2 0.2 0.3 0.3 0.2 0.1 0.2 0.1 0.2 0.1 -0.2 0.3 0.4 0.1 -0.1 -0.3 0.2 0.3 -0.0 0.1 0.1 0.0 -0.1 0.3 -0.0 0.2 -0.0 0.1 -0.2 0.1 -0.3 0.0 -0.8 0.2 0.0 -0.2 0.3
Illnesses of father: High blood pressure 1.4 1.7 2.3 1.4 1.3 1.5 1.3 1.5 1.4 1.1 1.3 1.5 1.2 1.2 1.2 1.2 1.5 1.4 1.2 1.3 1.3 1.3 1.3 1.3 1.3 1.4 1.3 1.5 1.1 1.3 1.3 1.0 1.5 1.1 1.4 1.4 1.1 1.2 1.3 1.4 1.4 0.6 1.5 -1.4 1.1 1.4
Alcohol drinker status: Never 0.0 0.0 0.3 -0.0 -0.0 -0.4 0.0 -0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.2 0.3 -0.1 0.1 0.1 -0.0 -0.0 -0.1 -0.0 0.0 -0.2 -0.0 -0.0 0.2 0.2 -0.0 -0.0 -0.1 0.0 0.2 0.1 -0.0 -0.2 -0.4 0.1 0.1 0.0 0.6 0.1 0.4 -0.5 0.0
Ever smoked 0.4 0.7 1.5 0.6 0.8 1.0 0.9 1.0 0.6 1.2 1.0 1.1 0.8 1.2 1.2 0.7 0.6 0.8 0.8 0.2 0.9 0.7 0.8 0.8 1.0 0.8 0.7 0.2 0.8 0.7 0.6 0.6 0.9 0.0 1.1 0.5 0.5 0.7 1.2 0.5 0.6 1.1 0.8 -0.6 0.9 0.8
Basal metabolic rate 1.3 7.1 9.2 2.7 2.9 2.1 2.8 2.8 2.8 2.7 2.8 2.6 3.0 2.6 2.7 2.5 2.9 2.7 2.7 2.6 2.9 3.0 2.7 2.3 2.4 2.9 2.9 2.2 2.5 2.7 2.8 2.4 2.8 2.8 2.9 2.8 2.1 2.5 2.7 3.0 2.8 1.9 2.7 -2.6 1.8 2.8
Leg fat percentage (left) 0.5 1.7 6.0 0.9 1.3 2.5 1.2 1.3 1.2 0.6 1.0 0.9 1.1 0.7 0.6 1.1 1.8 1.3 1.7 1.5 1.4 1.3 1.4 1.0 1.0 1.4 1.4 1.3 0.9 1.4 1.5 1.1 1.3 1.4 1.1 1.6 1.3 1.2 0.8 1.8 1.5 -0.2 1.3 -2.1 0.6 1.3
Arm fat-free mass (left) 0.9 4.5 6.8 2.1 2.4 1.4 2.3 2.2 2.2 2.2 2.2 2.1 2.5 2.1 2.2 2.0 2.4 2.2 2.1 2.2 2.4 2.4 2.2 1.9 1.9 2.3 2.4 1.6 2.0 2.1 2.3 1.9 2.2 2.0 2.3 2.3 1.4 1.9 2.2 2.6 2.3 1.5 2.1 -2.1 1.3 2.3
Number of operations (self-reported) 0.0 0.0 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.1 0.2 0.0 -0.0 0.3 0.1 -0.1 0.2 0.1 0.2 0.0 0.3 0.2 0.1 0.1 -0.0 0.1 0.1 -0.2 0.1 0.1 0.2 0.1 -0.0 -0.2 0.1 0.1 0.1 0.1 0.1 -0.4 0.2 0.2
Average weekly beer plus cider intake 0.7 1.0 2.2 0.8 1.1 0.9 1.0 1.1 1.0 0.6 0.8 0.7 1.0 0.8 0.6 1.1 1.2 1.1 0.9 1.1 1.1 1.1 1.0 1.0 1.0 1.0 1.1 0.9 0.9 0.9 1.1 1.3 1.0 1.3 1.0 1.1 0.8 1.3 0.7 1.0 1.1 -0.1 0.9 -1.5 0.8 1.0
Irritability 0.6 1.0 2.6 -0.9 -0.9 -0.7 -1.1 -1.0 -0.8 -1.1 -1.1 -1.1 -1.0 -1.1 -1.1 -0.9 -0.8 -1.0 -1.1 -0.9 -1.0 -0.9 -1.0 -1.1 -1.1 -1.0 -1.0 -1.0 -1.2 -1.0 -0.9 -1.0 -1.2 -0.9 -1.0 -0.8 -0.9 -0.8 -1.2 -0.9 -0.9 -1.3 -1.1 0.8 -1.6 -1.0
Risk taking 0.0 0.1 0.5 -0.1 0.2 0.7 0.2 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 0.2 0.1 0.2 0.2 0.4 0.3 0.3 0.2 0.1 0.3 0.2 0.3 0.1 0.1 0.1 0.4 -0.3 0.2 0.3 0.4 0.4 0.2 -0.1 -0.0 0.4 0.4 0.0 0.3 -0.4 -0.1 0.3
Ever had prostate specific antigen (PSA) test 1.5 1.7 2.3 1.1 1.4 1.5 1.4 1.2 1.3 1.5 1.5 1.5 1.4 1.4 1.5 1.2 1.1 1.3 1.4 0.9 1.5 1.3 1.3 1.0 1.1 1.4 1.3 1.2 1.2 1.5 1.3 1.2 1.4 1.0 1.4 1.3 1.4 1.2 1.4 1.2 1.3 0.7 1.3 -1.2 0.7 1.5
Fractured/broken bones in last 5 years 0.6 0.8 2.2 0.6 0.9 0.0 0.8 0.9 0.7 0.2 0.6 0.1 0.9 0.2 0.2 0.9 1.2 0.8 1.2 1.5 0.9 0.7 0.8 0.8 0.9 0.9 0.8 1.2 0.7 1.0 1.2 0.9 0.9 1.2 0.6 1.2 0.3 0.7 0.3 1.2 1.1 -0.1 1.0 -1.5 0.3 0.8
Age started oral contraceptive pill 0.0 0.0 0.3 0.2 0.1 0.1 -0.0 -0.1 0.1 -0.2 -0.1 -0.3 -0.1 0.0 -0.1 0.1 0.3 0.0 -0.2 0.2 -0.1 -0.1 0.1 -0.0 -0.0 -0.0 -0.2 0.4 0.1 0.2 0.1 0.6 -0.1 0.1 -0.2 0.0 0.0 -0.1 -0.1 0.2 0.0 0.2 -0.0 -0.3 -0.3 -0.1
Diastolic blood pressure, automated reading 0.4 1.1 2.7 -0.9 -1.0 -0.7 -0.9 -0.7 -0.9 -1.4 -1.1 -1.2 -0.9 -1.3 -1.4 -1.0 -0.9 -1.1 -1.1 -1.1 -0.9 -0.8 -0.9 -1.4 -1.4 -0.9 -0.9 -1.1 -1.3 -1.0 -1.0 -1.2 -0.7 -0.8 -1.1 -0.9 -1.3 -0.7 -1.3 -1.0 -0.9 -1.6 -0.7 0.1 -1.5 -0.9
Ever depressed for a whole week 0.8 1.0 2.2 -1.0 -1.1 -0.6 -0.9 -0.9 -1.0 -0.8 -1.0 -0.9 -1.1 -0.8 -0.9 -1.2 -1.3 -1.0 -0.8 -1.5 -1.0 -1.1 -1.0 -0.9 -0.9 -1.1 -1.2 -1.1 -1.0 -1.0 -1.2 -0.8 -0.8 -1.5 -1.0 -1.4 -0.8 -1.1 -0.9 -1.5 -1.3 -0.3 -0.9 0.9 -0.3 -1.1
Unable to work because of sickness or disability 1.9 2.4 3.9 -1.4 -1.6 -1.4 -1.6 -1.6 -1.5 -1.5 -1.6 -1.5 -1.6 -1.5 -1.5 -1.4 -1.5 -1.5 -1.3 -1.6 -1.6 -1.6 -1.6 -1.6 -2.0 -1.6 -1.6 -1.3 -1.6 -1.4 -1.7 -1.3 -1.6 -1.6 -1.5 -1.7 -1.4 -1.5 -1.5 -1.6 -1.7 -1.2 -1.6 1.7 -1.7 -1.6
Commuting to job workplace: Cycle 0.8 0.9 1.8 1.0 1.0 0.5 1.0 1.0 0.9 0.7 1.0 0.8 1.1 0.7 0.8 1.1 1.1 0.9 1.0 0.9 1.0 0.9 1.0 0.9 0.8 1.1 1.0 1.0 1.1 1.1 1.0 0.9 1.0 0.7 1.1 1.1 0.7 0.8 0.9 1.0 1.1 0.9 0.9 -1.4 0.8 1.1
Myopia 0.2 0.3 2.2 -1.3 -0.4 -0.5 -0.4 -0.5 -0.5 -0.6 -0.5 -0.6 -0.3 -0.5 -0.6 -0.6 -0.4 -0.2 -0.6 -0.4 -0.5 -0.4 -0.3 -0.2 -0.7 -0.4 -0.5 -0.9 -0.5 -0.4 -0.4 -0.6 -0.3 -0.8 -0.5 -0.5 -0.2 -0.8 -0.5 -0.6 -0.4 -1.5 -0.3 0.2 -0.6 -0.4
Vascular/heart problems diagnosed by doctor 0.5 1.4 7.2 1.4 1.1 1.2 1.0 0.9 1.2 1.3 1.1 1.0 1.0 1.2 1.2 1.0 0.9 1.0 1.2 1.3 1.0 0.9 1.0 1.4 1.6 1.0 0.9 1.3 1.3 1.1 1.1 1.4 0.8 1.2 1.0 1.2 1.1 1.2 1.3 1.2 1.1 2.7 1.0 -0.7 1.6 0.9
Cholesterol lowering medication 0.2 0.2 1.3 -0.7 -0.3 -0.3 -0.3 -0.2 -0.4 -0.5 -0.4 -0.2 -0.3 -0.4 -0.4 -0.3 -0.4 -0.4 -0.5 -0.7 -0.3 -0.4 -0.3 -0.5 -0.6 -0.3 -0.4 -0.7 -0.5 -0.5 -0.4 -0.8 -0.1 -0.6 -0.3 -0.5 -0.4 -0.6 -0.5 -0.5 -0.4 -1.2 -0.2 -0.0 -0.6 -0.3
Medication: Omeprazole (e.g. Zanprol) 2.2 2.7 5.1 -1.8 -1.6 -1.5 -1.7 -1.5 -1.6 -1.5 -1.5 -1.7 -1.6 -1.5 -1.5 -1.5 -1.8 -1.7 -1.6 -1.5 -1.6 -1.7 -1.7 -1.7 -1.6 -1.6 -1.8 -1.6 -1.3 -1.5 -1.6 -1.5 -1.9 -1.6 -1.7 -1.6 -1.7 -2.3 -1.5 -1.7 -1.6 -0.7 -1.8 1.4 -1.8 -1.7
Pain experienced in last month 0.0 0.1 0.3 -0.1 -0.2 -0.5 -0.1 -0.2 -0.3 -0.4 -0.2 -0.4 -0.1 -0.3 -0.3 -0.0 -0.1 -0.2 0.1 -0.2 -0.2 -0.1 -0.1 -0.2 -0.1 -0.2 -0.2 -0.1 -0.1 -0.1 -0.2 0.0 0.1 0.0 -0.4 -0.2 -0.3 -0.5 -0.2 -0.0 -0.2 0.5 -0.0 -0.2 -0.1 -0.2
Supplements: Calcium 1.9 2.0 4.2 -1.4 -1.5 -1.6 -1.6 -1.6 -1.5 -1.1 -1.4 -1.1 -1.6 -1.1 -1.1 -1.5 -1.4 -1.2 -1.6 -1.2 -1.5 -1.4 -1.5 -1.3 -1.3 -1.5 -1.4 -1.3 -1.3 -1.5 -1.4 -1.4 -1.7 -1.2 -1.4 -1.5 -1.3 -1.5 -1.3 -1.4 -1.5 -1.2 -1.7 2.0 -1.2 -1.5
Basal cell carcinoma (self-reported) 0.5 0.6 1.8 0.8 0.8 0.9 0.8 0.9 0.7 0.5 0.7 0.3 0.7 0.7 0.5 0.9 0.8 0.7 0.6 1.1 0.7 0.3 0.7 0.9 1.3 0.8 0.5 0.6 0.8 0.7 0.9 1.1 0.6 0.7 0.5 0.9 0.4 0.5 0.6 0.8 0.9 1.0 0.7 -1.3 0.8 0.6
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.1 0.4 0.8 0.9 0.8 0.7 0.8 0.9 0.8 1.1 0.8 0.9 0.9 0.9 0.6 0.9 0.7 0.7 0.9 0.9 0.8 0.6 0.5 0.8 0.9 0.7 0.6 0.7 0.7 0.4 0.5 0.7 0.8 0.7 0.8 0.7 0.8 0.8 0.8 -0.3 0.6 -0.1 0.3 0.9
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 2.8 -1.1 -1.3 -0.4 -1.3 -1.4 -1.2 -1.3 -1.3 -1.2 -1.4 -1.3 -1.2 -1.2 -1.0 -1.2 -1.2 -1.1 -1.3 -1.3 -1.2 -1.2 -1.1 -1.3 -1.3 -0.9 -1.3 -1.4 -1.2 -1.1 -1.4 -1.2 -1.3 -1.2 -1.7 -1.0 -1.3 -0.9 -1.2 -1.5 -1.4 1.3 -1.0 -1.3
Heart disease (siblings) 0.3 0.4 0.9 0.6 0.6 0.6 0.7 0.6 0.6 0.5 0.6 0.4 0.6 0.6 0.5 0.5 0.7 0.7 0.7 0.9 0.6 0.7 0.6 0.7 0.6 0.6 0.6 1.0 0.6 0.9 0.8 0.6 0.6 0.9 0.6 0.8 0.7 0.0 0.4 0.7 0.7 -0.0 0.8 -0.7 0.4 0.6
Alcohol drinker status: Previous 0.4 0.5 2.3 0.5 0.8 0.0 0.7 0.7 0.6 0.8 0.7 0.6 0.8 0.8 0.8 0.8 0.8 0.7 0.6 0.5 0.7 0.4 0.7 0.8 0.7 0.7 0.5 0.4 0.9 0.7 0.6 1.0 0.7 -0.0 0.7 0.5 0.5 0.4 0.8 0.7 0.6 1.5 0.6 -0.9 0.6 0.6
Pack years of smoking 0.1 0.1 0.6 0.3 0.2 -0.3 0.1 0.1 0.1 -0.2 -0.0 -0.2 0.2 -0.2 -0.2 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.1 -0.1 -0.2 0.2 0.1 0.4 0.1 0.4 0.4 0.3 0.2 0.6 0.1 0.5 -0.1 -0.4 -0.2 0.5 0.4 -0.1 0.1 -0.6 -0.4 0.1
Impedance of whole body 0.6 3.1 5.1 -1.2 -2.0 -0.6 -1.9 -1.6 -1.9 -1.8 -1.9 -1.5 -2.2 -1.8 -1.8 -1.8 -1.9 -1.9 -1.6 -2.3 -2.1 -1.8 -1.8 -1.7 -1.7 -2.0 -1.9 -1.4 -1.9 -1.8 -2.1 -1.8 -1.5 -1.3 -1.9 -2.1 -0.9 -1.2 -1.8 -2.2 -2.0 -1.2 -1.6 2.0 -0.8 -1.9
Leg fat mass (left) 0.8 3.0 6.7 1.5 1.8 2.6 1.8 1.7 1.7 1.2 1.5 1.3 1.7 1.2 1.2 1.5 2.2 1.8 2.1 2.0 1.9 1.8 1.8 1.4 1.5 1.9 1.9 1.7 1.4 1.8 2.0 1.6 1.8 1.9 1.6 2.1 1.7 1.7 1.3 2.3 2.0 0.4 1.8 -2.4 1.0 1.8
Arm predicted mass (left) 0.7 3.4 5.2 1.7 2.1 1.2 2.0 1.9 2.0 1.9 1.9 1.8 2.2 1.9 1.9 1.7 2.0 1.9 1.8 1.9 2.1 2.1 1.9 1.6 1.6 2.0 2.1 1.2 1.7 1.8 2.0 1.6 1.9 1.7 2.0 2.0 1.1 1.6 1.9 2.3 2.0 1.1 1.8 -1.8 1.0 2.0