Best TWAS P=4.16e-11 · Best GWAS P=1.26e-11 conditioned to 0.000823
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | UXS1 | 0.14 | 0.07 | enet | 13 | 0.06 | 5.5e-05 | 1.6 | 5.2 | 1.8e-07 | 0.49 | 0.13 | 0.82 | FALSE |
2 | METSIM | Adipose | NCK2 | 0.04 | 0.02 | blup | 658 | 0.02 | 1.0e-03 | 5.5 | 6.3 | 3.6e-10 | 0.70 | 0.13 | 0.80 | FALSE |
3 | NTR | Blood | NCK2 | 0.04 | 0.01 | bslmm | 676 | 0.02 | 1.5e-08 | 6.4 | 6.6 | 4.2e-11 | 0.63 | 0.02 | 0.98 | TRUE |