Best TWAS P=2.71e-13 · Best GWAS P=1.36e-61 conditioned to 6.37e-48
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | ANAPC1 | 0.05 | 0.02 | lasso | 5 | 0.01 | 9.8e-03 | -2.442 | -5.4 | 6.9e-08 | -0.07 | 0.10 | 0.40 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LOC541471 | 0.03 | 0.00 | enet | 13 | 0.01 | 2.6e-03 | 2.617 | 5.2 | 1.9e-07 | 0.22 | 0.04 | 0.02 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC541471 | 0.12 | 0.03 | blup | 62 | 0.06 | 8.3e-08 | 0.013 | 7.3 | 2.7e-13 | 0.51 | 0.10 | 0.88 | TRUE |