Best TWAS P=3.74e-19 · Best GWAS P=2.28e-21 conditioned to 0.000168
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RP11-222K16.2 | 0.08 | 0.04 | lasso | 9 | 0.05 | 2.1e-08 | -3.3 | -5.7 | 1.2e-08 | -0.58 | 0.99 | 0.01 | FALSE |
| 2 | NTR | Blood | EOMES | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.0e-08 | 9.5 | 8.9 | 3.7e-19 | 0.82 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | EOMES | 0.11 | 0.10 | enet | 10 | 0.10 | 1.3e-10 | 7.5 | 7.3 | 2.8e-13 | 0.67 | 0.97 | 0.03 | FALSE |