Best TWAS P=6.27e-10 · Best GWAS P=6.02e-20 conditioned to 9.11e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | CRTAP | 0.16 | 0.04 | lasso | 4 | 0.11 | 1.7e-05 | -2.7 | -5.5 | 3.7e-08 | -0.26 | 0.56 | 0.03 | FALSE |
| 2 | GTEx | Thyroid | GLB1 | 0.30 | 0.20 | enet | 16 | 0.21 | 5.1e-16 | -6.2 | -5.6 | 1.9e-08 | -0.23 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Thyroid | CRTAP | 0.23 | 0.10 | enet | 26 | 0.16 | 1.9e-12 | -6.2 | -6.2 | 6.3e-10 | -0.27 | 0.99 | 0.00 | TRUE |
| 4 | YFS | Blood | CCR4 | 0.04 | 0.01 | bslmm | 354 | 0.01 | 1.5e-05 | -3.0 | -5.6 | 2.5e-08 | -0.27 | 0.43 | 0.10 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CRTAP | 0.02 | 0.01 | blup | 55 | 0.01 | 1.4e-03 | -4.1 | -5.8 | 7.8e-09 | -0.29 | 0.06 | 0.14 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | CRTAP | 0.07 | 0.03 | blup | 55 | 0.04 | 4.3e-05 | -4.0 | -5.9 | 4.2e-09 | -0.34 | 0.31 | 0.38 | FALSE |