Best TWAS P=1.09e-09 · Best GWAS P=2.32e-14 conditioned to 1.63e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NBEAL2 | 0.02 | 0.03 | lasso | 2 | 0.02 | 7.8e-04 | 5.3 | -5.3 | 1.1e-07 | 0.06 | 0.00 | 0.99 | FALSE |
| 2 | GTEx | Artery Tibial | NBEAL2 | 0.07 | 0.03 | enet | 19 | 0.07 | 6.3e-06 | 5.3 | -5.8 | 6.5e-09 | 0.05 | 0.01 | 0.96 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | CCR1 | 0.13 | 0.07 | lasso | 6 | 0.07 | 8.9e-06 | -5.9 | -5.6 | 2.7e-08 | 0.63 | 0.99 | 0.00 | FALSE |
| 4 | YFS | Blood | CXCR6 | 0.05 | 0.04 | lasso | 13 | 0.06 | 8.5e-19 | -5.8 | 6.0 | 1.9e-09 | -0.59 | 0.89 | 0.11 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FYCO1 | 0.06 | 0.05 | blup | 81 | 0.07 | 1.6e-13 | 3.9 | -6.1 | 1.1e-09 | 0.55 | 1.00 | 0.00 | TRUE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | FYCO1 | 0.08 | 0.01 | blup | 81 | 0.04 | 3.9e-05 | 4.3 | -6.0 | 2.5e-09 | 0.59 | 0.08 | 0.42 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CCR3 | 0.07 | 0.00 | blup | 76 | 0.03 | 1.0e-04 | -5.4 | 5.4 | 8.3e-08 | -0.58 | 0.02 | 0.83 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FYCO1 | 0.14 | 0.17 | blup | 81 | 0.18 | 2.7e-18 | 4.0 | -5.6 | 1.9e-08 | 0.49 | 1.00 | 0.00 | FALSE |