TWAS hub - NBEAL2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0220	0.0120	3.0e-03	0.031	0.016	0.015	0.016	0.023	1.0e-04	4.4e-03	5.9e-03	3.8e-03	7.8e-04
2	GTEx	Artery Tibial	0.0732	0.0382	6.9e-04	0.025	NA	0.067	NA	0.045	4.2e-03	NA	6.3e-06	NA	1.9e-04
3	GTEx	Brain Cerebellum	0.1660	0.0880	3.0e-03	0.076	NA	0.027	NA	0.022	2.9e-03	NA	5.4e-02	NA	7.3e-02
4	GTEx	Cells Transformed fibroblasts	0.0750	0.0400	6.4e-03	-0.004	NA	0.000	NA	-0.001	8.2e-01	NA	3.4e-01	NA	3.9e-01
5	GTEx	Esophagus Mucosa	0.0620	0.0320	5.1e-03	0.008	NA	0.043	NA	0.031	8.7e-02	NA	6.8e-04	NA	3.5e-03
6	GTEx	Esophagus Muscularis	0.1360	0.0720	6.4e-04	0.053	NA	0.036	NA	0.039	3.9e-04	NA	3.0e-03	NA	1.9e-03
7	GTEx	Lung	0.0381	0.0216	6.1e-03	0.007	NA	-0.004	NA	-0.001	8.9e-02	NA	9.4e-01	NA	3.6e-01
8	GTEx	Muscle Skeletal	0.1037	0.0384	6.2e-05	0.018	NA	0.020	NA	0.025	6.2e-03	NA	3.8e-03	NA	1.4e-03
9	GTEx	Nerve Tibial	0.1878	0.0603	2.7e-07	0.142	NA	0.158	NA	0.172	3.0e-10	NA	2.8e-11	NA	3.1e-12
10	GTEx	Testis	0.1500	0.0540	5.0e-06	0.106	NA	0.121	NA	0.104	2.0e-05	NA	5.3e-06	NA	2.3e-05
11	GTEx	Thyroid	0.2090	0.0610	6.9e-12	0.086	NA	0.126	NA	0.112	4.0e-07	NA	7.2e-10	NA	7.2e-09
12	METSIM	Adipose	0.0286	0.0188	2.0e-02	0.001	0.004	0.010	0.007	0.008	1.8e-01	7.8e-02	9.8e-03	2.6e-02	1.8e-02
13	ROSMAP	Brain Pre-frontal Cortex	0.0503	0.0196	1.9e-06	0.053	0.043	0.040	0.040	0.042	2.0e-07	2.6e-06	5.4e-06	5.4e-06	3.6e-06
14	YFS	Blood	0.0839	0.0305	5.9e-06	0.030	0.027	0.032	0.032	0.025	4.3e-10	3.3e-09	9.7e-11	1.1e-10	1.1e-08
15	TCGA	Bladder Urothelial Carcinoma	0.1000	0.0640	2.3e-03	0.011	0.037	0.038	NA	0.019	3.7e-02	4.3e-04	3.3e-04	NA	9.2e-03
16	TCGA	Brain Lower Grade Glioma	0.0216	0.0131	1.2e-03	0.023	0.009	0.000	NA	0.010	1.0e-03	2.7e-02	2.8e-01	NA	2.3e-02
17	TCGA	Pancreatic Adenocarcinoma	0.0830	0.0630	2.7e-03	0.078	0.070	0.063	NA	0.073	3.7e-04	7.0e-04	1.3e-03	NA	5.3e-04
18	TCGA	Prostate Adenocarcinoma	0.0528	0.0254	1.4e-08	0.074	0.074	0.061	NA	0.066	3.7e-08	3.7e-08	5.3e-07	NA	1.8e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Blood White Count	12.3	91.3	179.6	-3.3	-4.4	-10.1	-4.7	-12.5	13.4	-8.8	-3.7	-11.9	-9.9	8.4	-12.3	11.4	-2.5	-12.7	-13.2	-11.4
Vitamin and mineral supplements	7.2	9.8	20.0	-1.8	-1.6	-3.8	-1.0	-4.1	4.5	-2.8	-1.8	-3.9	-3.8	3.4	-2.8	2.4	-1.5	-4.0	-4.3	-4.0
Reaction Time	7.1	13.6	24.2	-2.7	-4.1	-4.3	-3.5	-4.5	4.0	-4.1	-3.3	-4.3	-4.9	1.3	-3.9	0.9	-2.9	-4.3	-4.2	-4.5
Waist Hip Ratio (WHR)	7.0	31.5	61.5	-3.2	-4.3	-6.9	-4.1	-7.1	7.8	-6.0	-3.6	-6.6	-6.4	4.7	-5.4	4.3	-1.3	-7.3	-7.6	-6.9
Medication: Lansoprazole	6.8	7.7	15.2	-2.8	-3.5	-3.5	-2.2	-3.2	2.8	-2.3	-3.3	-2.9	-3.9	1.0	-2.8	0.9	-2.1	-3.0	-3.0	-3.4
Mean time to correctly identify matches	6.1	11.5	25.6	-3.5	-4.6	-4.0	-2.9	-3.7	3.1	-3.4	-3.7	-3.6	-5.1	0.6	-3.5	-1.2	-3.2	-3.4	-3.4	-4.0
Multivitamins +/- minerals	5.5	7.0	14.9	0.9	1.2	3.2	0.9	3.5	-3.9	2.0	1.2	3.2	3.2	-3.3	2.2	-2.2	0.9	3.5	3.8	3.4
Type 2 Diabetes (T2D) (2012)	5.3	6.1	11.4	-2.3	-1.3	-2.7	-1.7	-2.9	2.5	-2.3	-2.1	-2.7	-3.3	1.6	-2.7	2.0	-3.4	-3.1	-2.5	-3.0
Heel bone mineral density (BMD) T-score, automated (right)	5.1	11.6	21.7	-3.5	-1.7	-3.9	-2.8	-4.5	4.5	-2.0	-2.5	-4.5	-3.9	1.5	-3.0	2.1	-3.3	-4.2	-4.7	-4.4
Bipolar Disorder (2011)	4.7	4.6	16.7	0.0	0.0	2.8	1.6	2.7	-2.7	1.7	0.0	2.6	3.3	-1.8	0.7	-0.3	4.1	2.7	0.0	3.0
Type 2 Diabetes (T2D) (2018)	4.6	8.7	22.9	-1.9	-1.8	-2.9	-1.7	-3.5	3.2	-3.1	-1.9	-3.3	-3.7	4.8	-2.3	3.3	-1.7	-3.4	-3.5	-3.2
Diabetes (mother)	4.6	5.8	10.6	-0.6	-0.9	-2.4	-2.4	-2.9	3.0	-3.3	-1.0	-2.9	-2.3	2.6	-2.5	3.1	-1.1	-3.0	-3.1	-2.8
Diabetes diagnosed by doctor	4.1	6.7	23.7	-1.6	-1.5	-2.6	-1.6	-3.0	3.0	-2.7	-1.6	-3.0	-3.2	4.9	-1.4	2.5	-0.9	-3.0	-3.2	-2.8
Financial situation satisfaction	3.7	4.6	9.6	-1.0	-0.4	-2.2	-0.9	-2.9	3.1	-1.1	-0.9	-3.1	-1.8	2.5	-2.1	2.1	-1.7	-2.9	-3.1	-2.7
Ever smoked	3.6	6.3	13.6	1.0	0.6	2.6	1.3	3.5	-3.3	1.8	1.7	3.3	2.6	-2.2	2.4	-2.7	1.2	3.7	3.7	3.3
Myopia	3.6	5.3	11.1	1.4	1.0	2.6	1.2	3.0	-3.3	1.9	1.3	3.0	2.0	-1.3	3.1	-2.7	1.7	2.7	3.1	2.7
HDL Cholesterol	3.5	5.8	10.3	3.2	3.0	2.7	2.8	2.5	-1.9	2.6	2.5	2.4	2.5	-0.5	3.2	0.9	2.6	2.3	2.0	2.7
Heel T-Score	3.5	28.2	52.6	-4.3	-1.9	-5.8	-3.6	-7.0	6.7	-2.7	-4.0	-6.7	-6.2	6.1	-4.2	4.8	-3.7	-7.2	-7.1	-6.6
Allergy or Eczema	3.4	8.9	21.8	1.0	1.2	2.7	0.1	3.7	-4.2	1.8	1.1	3.9	3.2	-4.1	2.8	-4.7	1.4	4.0	3.9	3.2
Depression (self-reported)	3.4	4.0	6.9	1.9	2.5	2.5	2.0	2.3	-2.2	1.8	2.3	2.6	2.5	-0.6	1.4	-0.3	2.3	2.1	2.0	2.2
Birth weight	3.1	6.7	19.4	0.6	1.0	2.6	0.8	3.2	-3.2	3.0	0.6	2.8	3.3	-4.4	2.0	-3.1	0.2	3.2	3.3	3.0
Medication: Metformin	3.0	4.3	17.0	-1.0	-0.0	-1.9	-1.1	-2.3	2.5	-1.4	-0.9	-2.5	-1.9	4.1	-1.7	3.1	-1.2	-2.3	-2.4	-2.1
Hayfever, allergic rhinitis or eczema	3.0	6.5	17.4	1.1	0.8	2.4	0.1	3.1	-3.4	1.8	1.0	2.9	2.9	-3.7	2.7	-4.2	0.4	3.3	3.2	2.7
Diabetes (self-reported)	2.9	4.4	20.9	-1.1	-1.0	-2.0	-1.0	-2.3	2.3	-2.3	-1.5	-2.3	-2.6	4.6	-0.9	1.8	-1.0	-2.4	-2.4	-2.1
Schizophrenia vs Biploar Disorder	2.8	3.6	8.4	-2.2	-2.9	-2.2	-2.7	-1.6	1.7	-2.0	-2.8	-1.7	-2.3	-0.2	-0.7	0.2	-2.9	-1.5	0.0	-1.8
Ovarian Cancer	2.8	3.7	7.1	-2.3	-1.7	-2.4	-1.6	-2.1	1.9	-1.5	-2.5	-2.3	-2.5	-0.1	-1.9	-0.7	-2.7	-1.7	-1.8	-2.2
Maternal smoking around birth	2.8	4.1	6.5	-1.4	-2.3	-2.2	-2.0	-2.5	2.3	-1.8	-1.9	-2.4	-2.1	0.7	-1.7	1.9	-2.4	-2.2	-2.5	-2.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.2	8.4	2.9	2.6	2.4	1.6	2.4	-1.9	1.2	2.9	2.4	2.2	0.5	1.3	1.6	2.2	2.3	1.8	2.2
Crohns Disease (2017)	2.7	6.0	18.8	4.3	3.5	2.6	2.5	1.5	-1.0	0.7	3.6	1.9	2.8	2.5	0.4	3.9	2.9	1.0	1.0	2.0
Average weekly spirits intake	2.7	3.3	14.1	-0.4	-0.8	1.2	0.3	2.1	-1.8	2.3	0.2	1.3	2.0	-2.9	1.9	-3.8	0.8	2.1	2.1	1.8
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.1	12.2	-2.4	-0.9	-2.8	-2.1	-3.2	3.5	-0.8	-1.5	-3.5	-2.8	1.3	-1.5	1.9	-2.6	-3.1	-3.5	-3.3
Breastfed as a baby	2.7	3.3	10.1	0.4	0.8	1.6	1.3	1.9	-2.4	2.4	0.4	2.0	1.6	-3.2	1.5	-2.7	1.2	1.8	2.2	1.7
Eye problems/disorders: Diabetes related eye disease	2.6	2.9	14.5	-0.8	-1.1	-1.7	-0.9	-2.0	1.7	-1.6	-1.2	-1.7	-2.3	3.8	-0.6	1.1	-0.1	-2.1	-2.0	-1.8
Pulse rate	2.6	4.4	11.2	-1.1	-0.1	-2.5	-0.1	-2.9	3.3	-0.1	-1.1	-3.2	-2.2	2.4	-1.6	1.9	-0.2	-2.9	-3.0	-2.5
Comparative body size at age 10	2.6	7.1	12.4	2.7	1.1	3.4	2.6	3.1	-3.3	3.2	2.5	3.2	3.3	0.4	2.3	-0.6	1.5	3.3	3.4	3.5
Smoking status: Previous	2.6	3.9	8.2	0.7	-0.6	2.1	1.2	2.8	-2.5	0.8	1.4	2.8	1.7	-1.5	1.9	-2.0	1.4	2.9	2.9	2.6
Supplements: Fish oil (including cod liver oil)	2.6	3.4	5.7	1.1	0.9	2.3	1.5	2.4	-2.3	1.9	1.9	2.3	2.0	-1.9	1.4	-1.5	0.7	2.4	2.4	2.3
Neuroticism (2016)	2.5	3.6	10.2	2.7	1.4	2.5	2.2	1.9	-1.6	0.8	3.2	2.0	2.0	-0.0	1.5	0.1	1.9	2.2	1.6	2.2
Diverticular disease/diverticulitis (self-reported)	2.5	2.9	6.3	-2.3	-2.5	-2.1	-1.2	-1.7	1.5	-0.9	-2.5	-1.5	-2.5	-1.0	-0.9	-1.3	-1.8	-1.5	-1.5	-1.8
Qualifications: O levels/GCSEs or equivalent	2.5	4.0	10.1	-1.8	-3.1	-2.1	-3.2	-1.9	1.2	-2.5	-2.2	-1.4	-1.7	-1.4	-1.8	-0.1	-2.3	-1.8	-1.9	-2.4
Knee pain experienced in last month	2.5	4.0	8.5	-1.8	-1.8	-2.4	-2.0	-2.3	2.6	-2.3	-1.4	-2.2	-1.6	1.1	-2.9	1.7	0.4	-2.1	-2.6	-2.1
Ever depressed for a whole week	2.5	3.1	6.3	2.5	0.7	2.3	1.4	2.0	-2.2	0.6	2.5	2.5	1.8	0.1	1.7	0.6	1.6	2.1	1.9	1.9
Irritable Bowel Disease (IBD)	2.4	5.7	26.3	4.0	2.9	2.0	2.4	0.7	-0.5	0.2	3.4	1.2	1.7	4.2	0.1	5.1	2.2	0.3	0.5	1.4
Past tobacco smoking	2.4	4.4	9.7	-0.7	0.5	-2.1	-0.8	-3.0	2.8	-0.8	-1.3	-3.0	-1.8	1.9	-1.9	2.5	-1.1	-3.1	-3.1	-2.7
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	7.7	1.8	0.1	2.1	0.9	2.1	-2.8	0.5	1.3	2.7	1.5	-0.7	2.0	-1.1	1.1	2.0	2.1	1.9
Ever highly irritable/argumentative for 2 days	2.3	2.7	7.3	2.6	1.8	2.0	1.4	1.4	-1.2	2.7	1.9	1.3	1.8	1.4	1.8	1.0	1.4	1.3	1.2	1.7
Cholesterol lowering medication	2.3	3.4	11.9	0.8	0.0	-1.1	0.6	-2.1	2.5	-2.0	0.6	-2.0	-1.6	3.5	-1.4	3.1	0.2	-2.1	-2.5	-1.6
Mineral and other dietary supplements	2.2	3.0	5.3	-1.2	-0.2	-2.0	-0.7	-2.3	2.2	-0.9	-1.7	-2.3	-1.8	2.1	-1.3	1.9	-0.7	-2.2	-2.3	-2.1
Angina (self-reported)	2.1	2.8	12.1	-0.0	1.5	-1.3	1.3	-1.7	2.4	-0.2	0.3	-1.5	-1.3	3.5	-1.7	2.6	0.7	-1.5	-2.4	-1.5
Lupus	2.0	3.1	6.6	-2.5	-2.2	-1.8	-2.3	-1.4	1.3	-1.1	-2.6	-1.6	-1.0	-1.4	-0.4	-2.4	-2.2	-1.3	-1.7	-1.9
Diabetes (father)	2.0	2.5	7.7	0.3	-1.4	-1.3	-1.2	-1.7	1.8	-1.8	-0.1	-1.7	-1.6	2.8	-1.6	2.3	-0.4	-1.6	-1.8	-1.5
Average weekly fortified wine intake	2.0	2.3	5.4	1.9	2.2	1.9	1.3	1.5	-1.7	1.7	1.7	1.6	2.3	0.0	1.1	-0.0	0.9	1.6	1.4	1.5
Heart attack	2.0	2.5	5.0	-1.2	-0.7	-2.0	-0.9	-1.9	2.1	-1.2	-0.9	-1.8	-1.8	1.9	-2.2	1.5	-0.6	-1.6	-2.2	-2.0
Allergy	2.0	4.6	18.6	0.0	0.0	-1.6	0.3	-2.4	3.0	-1.6	0.3	-2.5	-2.0	3.7	-2.0	4.3	0.1	-2.7	-2.6	-1.9
Pulse wave reflection index	2.0	2.4	4.5	1.7	1.6	2.1	0.4	2.0	-2.0	0.4	1.7	2.0	2.1	0.2	1.3	0.2	1.1	1.9	1.9	2.0
Medication: Seretide 50 evohaler	2.0	2.4	10.5	-0.5	-0.3	1.0	-0.3	1.9	-2.0	1.4	-0.3	1.3	1.2	-1.9	1.6	-3.2	-0.4	2.1	2.2	1.5
Medication: Bendroflumethiazide	1.9	2.9	6.4	2.5	1.8	1.5	2.2	1.4	-0.7	2.0	2.5	1.4	1.2	0.8	2.3	2.0	2.3	1.5	0.7	1.4
Smoking Status	1.8	4.2	9.6	1.0	-0.3	2.6	1.3	2.8	-3.0	1.6	1.2	2.5	2.0	-1.7	1.9	-1.6	-0.4	3.0	3.1	2.7
Lung FEV1/FVC ratio	1.8	9.2	16.6	-3.5	-2.7	-3.5	-2.7	-3.8	3.4	-2.5	-3.4	-3.6	-3.8	1.1	-1.8	-0.8	-4.1	-3.4	-3.3	-3.6
Hand grip strength (left)	1.8	4.7	15.7	1.7	3.1	2.6	1.9	1.8	-1.3	3.7	2.3	1.1	4.0	-2.9	1.2	0.6	-0.4	2.0	1.7	2.1
Angina	1.8	2.4	13.1	0.1	1.5	-1.0	1.5	-1.4	2.1	0.0	0.5	-1.1	-1.2	3.6	-1.2	2.2	1.1	-1.2	-2.1	-1.2
Qualifications: College or University degree	1.8	5.7	12.0	-1.7	-0.1	-2.5	-0.9	-3.2	2.5	-2.0	-1.7	-2.5	-3.5	0.9	-2.5	2.2	-3.1	-3.1	-3.0	-3.2
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	8.1	1.7	0.9	2.0	1.3	2.0	-2.3	1.2	0.9	2.2	0.8	1.0	1.6	-1.5	2.8	1.8	1.9	2.1
Bipolar Disorder (2018)	1.7	2.7	5.5	1.5	1.5	2.0	1.1	2.1	-2.3	1.8	1.6	2.2	1.9	0.0	1.0	-0.7	0.7	1.9	2.2	2.0
HbA1C	1.7	1.9	12.4	0.0	0.4	-0.6	-0.5	-1.2	1.5	-1.0	1.0	-0.9	-1.0	3.5	-1.0	2.8	-0.4	-0.9	-1.5	-1.1
Triglycerides	1.7	2.8	4.8	-1.8	-1.7	-2.0	-1.6	-1.9	1.9	-1.7	-1.5	-2.2	-1.8	1.4	-1.9	-0.2	-1.7	-1.7	-1.6	-1.9
Blood Eosinophil Count	1.7	12.8	33.7	-5.3	-5.8	-3.8	-4.9	-3.0	1.7	-3.9	-5.1	-2.5	-3.5	0.1	-3.9	-1.8	-3.6	-3.1	-2.4	-3.5
Qualifications: CSEs or equivalent	1.7	2.3	11.4	0.5	-1.2	-0.6	-1.5	-1.6	1.5	-1.7	0.4	-1.3	-0.9	1.2	-2.0	3.4	-0.9	-1.8	-1.9	-1.4
Supplements: Glucosamine	1.7	2.2	4.0	1.4	1.2	1.7	1.0	1.9	-1.5	1.6	1.5	1.5	1.7	-1.3	1.7	-0.8	1.0	2.0	1.8	1.8
Hip circumference	1.7	7.5	15.0	2.8	3.4	3.1	2.6	2.9	-1.5	2.9	3.6	2.2	3.9	2.2	2.7	0.3	3.2	3.1	2.1	3.3
Leg pain on walking	1.7	2.2	4.5	-0.9	-1.1	-1.8	-1.8	-1.6	2.1	-1.4	-1.3	-1.8	-1.4	0.1	-1.4	1.3	-0.4	-1.8	-2.1	-1.8
Alcohol drinker status: Previous	1.7	1.9	4.8	0.7	2.2	1.6	1.4	1.6	-1.4	1.4	1.5	1.1	1.7	-0.5	1.2	0.5	0.6	1.6	1.8	1.8
Crohns Disease (2012)	1.6	2.6	10.0	2.1	2.4	1.7	1.6	1.8	-1.7	0.7	1.5	1.8	1.7	-0.7	1.2	0.1	3.2	1.4	0.0	1.8
Number of incorrect matches in round	1.6	2.6	5.1	1.7	1.6	1.6	1.9	2.0	-1.6	0.9	1.3	1.7	1.2	0.6	2.2	-1.1	2.1	1.9	1.7	1.9
Suffer from ‘nerves’	1.6	2.5	5.4	1.7	0.7	2.0	2.0	1.9	-1.9	0.3	1.5	2.1	1.2	-0.2	1.0	-1.0	2.3	1.7	1.8	2.0
Pain type(s) experienced in last month: Hip pain	1.6	2.0	3.8	-1.3	-1.6	-1.8	-1.7	-1.5	1.5	-1.3	-1.3	-1.3	-2.0	-1.3	-1.1	0.1	-1.5	-1.1	-1.6	-1.7
Heart attack/myocardial infarction (self-reported)	1.6	2.0	4.3	-1.0	-0.4	-1.8	-0.5	-1.6	2.0	-0.8	-0.6	-1.7	-1.5	1.8	-2.0	1.6	-0.4	-1.3	-2.1	-1.7
Friendships satisfaction	1.5	1.8	3.8	-0.7	-0.7	-1.5	-2.0	-1.7	1.3	-1.6	-0.8	-1.2	-1.8	1.3	-0.2	0.2	-1.5	-1.6	-1.7	-1.8
Ulcerative Colitis (UC)	1.4	2.7	16.3	2.4	1.5	1.0	1.2	0.0	-0.1	-0.3	2.0	0.4	0.4	4.0	0.1	4.0	1.0	-0.3	0.1	0.6
Blood Platelet Count	1.4	16.3	48.3	7.0	5.4	4.7	4.3	2.8	-1.9	1.9	6.6	3.0	4.6	2.2	1.9	5.0	5.3	2.4	2.1	3.8
Hearing difficulty/problems: Yes	1.4	2.1	4.0	-0.7	-0.8	-2.0	-0.7	-1.6	1.9	-1.5	-1.0	-1.8	-1.9	1.7	-1.2	1.5	-1.0	-1.8	-1.6	-1.8
Impedance of leg (left)	1.4	6.9	11.8	-1.9	-2.9	-2.9	-3.4	-3.0	2.7	-2.6	-2.6	-3.2	-2.8	-2.4	-1.3	0.0	-2.5	-3.1	-3.0	-3.3
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	5.7	0.8	0.3	1.4	0.7	1.5	-1.8	0.2	1.1	1.8	1.2	-1.8	1.0	-2.4	0.7	1.9	1.7	1.6
Happiness	1.4	1.7	4.8	-0.5	-0.3	-1.1	-2.2	-1.5	1.3	-1.9	-0.6	-1.4	-1.0	1.3	-0.1	0.6	-1.9	-1.7	-1.4	-1.5
Birth weight of first child	1.4	2.5	7.0	0.8	1.1	1.8	1.0	1.7	-1.4	1.6	1.3	1.4	2.3	-1.8	1.4	-2.6	1.4	1.6	1.6	1.9
Systolic Blood Pressure	1.3	6.6	13.5	-0.6	-1.6	-2.2	-2.2	-3.3	2.6	-3.1	-1.7	-2.8	-2.7	2.0	-2.3	2.5	-3.0	-3.5	-3.7	-3.4
Chronotype (morning person)	1.3	2.9	9.4	-0.7	1.5	-1.4	0.4	-2.0	2.4	-0.3	-0.1	-2.5	-1.5	3.1	-1.3	2.4	-0.7	-2.3	-2.0	-1.6
Impedance of leg (right)	1.3	6.4	11.6	-2.0	-3.0	-2.6	-3.2	-2.9	2.4	-2.3	-2.6	-2.8	-2.6	-3.4	-1.2	-0.7	-2.4	-2.9	-2.8	-3.1
Medication: Atenolol	1.3	1.7	5.8	1.8	1.8	1.0	2.4	0.6	-0.1	1.0	1.5	0.5	1.1	1.9	0.5	2.4	0.9	0.6	0.3	0.9
Body mass index (BMI)	1.3	5.5	20.1	3.1	2.4	1.9	2.5	1.6	-0.1	1.6	3.5	1.2	2.5	4.5	0.8	2.5	3.7	1.7	0.7	2.1
Pain all over the body in last month	1.3	1.4	3.1	1.4	0.6	1.1	0.6	1.4	-1.1	0.5	1.5	1.5	1.2	0.5	1.1	0.9	1.8	1.5	1.2	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	8.1	-2.1	-1.4	-2.2	-2.2	-2.7	2.2	-2.4	-2.0	-2.7	-1.9	-0.1	-1.7	0.9	-2.0	-2.8	-2.1	-2.4
Worry too long after embarrassment	1.3	2.1	4.9	-1.0	-1.1	-1.7	-1.1	-1.7	1.6	-2.0	-0.9	-1.4	-2.2	2.1	-1.1	0.8	0.3	-1.9	-1.5	-1.6
Pulse rate, automated reading	1.3	4.0	10.4	-1.0	0.4	-2.0	0.7	-2.8	3.2	0.7	-0.9	-2.8	-1.9	1.1	-2.5	2.1	1.3	-2.7	-3.2	-2.3
Medication: Aspirin	1.3	1.7	13.3	-0.4	0.9	-0.9	1.1	-0.9	1.2	-0.2	-0.4	-0.9	-1.2	3.6	-1.7	1.7	0.7	-1.1	-1.4	-0.9
Risk taking	1.3	1.9	7.5	-0.2	-0.4	-1.4	-0.7	-1.6	1.8	-2.1	-0.5	-1.3	-0.7	0.6	-2.7	1.9	0.5	-1.4	-2.0	-1.4
Pain experienced in last month	1.3	2.1	4.7	0.4	2.0	1.6	1.6	1.3	-1.8	2.2	0.6	1.3	1.5	-1.3	1.5	-2.1	-0.3	1.3	1.6	1.2
Age at First Birth	1.2	1.7	3.9	-1.0	-0.4	-1.5	-1.0	-1.6	1.7	-0.6	-1.1	-1.6	-1.8	1.7	-0.1	0.4	-0.9	-1.5	-2.0	-1.8
Fasting Glucose	1.2	1.4	4.5	1.5	1.8	1.2	1.8	0.9	-0.4	0.9	2.1	0.8	0.8	0.3	1.7	0.4	1.1	1.4	0.4	1.1
BMI	1.2	7.2	21.4	3.6	2.7	2.5	2.9	2.2	-0.7	2.0	3.8	1.9	3.1	4.6	1.7	2.1	3.8	2.4	1.4	2.8
Medication: Levothyroxine sodium	1.2	2.1	4.8	1.2	1.2	1.6	1.2	2.0	-1.8	1.0	1.1	2.2	1.6	-0.2	1.3	-0.4	1.2	2.1	1.7	1.8
Hair/balding pattern: Pattern 3	1.2	1.7	4.6	-1.9	-2.1	-1.4	-1.4	-0.8	0.3	-0.3	-1.9	-0.6	-1.3	-1.8	-0.8	-1.5	-2.1	-0.8	-0.5	-1.2
Hair/balding pattern: Pattern 4	1.2	2.8	4.7	1.3	1.8	1.9	1.9	2.1	-1.9	2.0	1.6	2.2	1.9	-0.3	1.6	-0.8	1.4	2.0	1.9	1.9
Health satisfaction	1.2	1.5	6.9	2.6	1.8	0.9	0.6	0.3	0.4	0.8	2.1	-0.1	1.1	2.2	0.7	1.9	0.9	0.3	-0.3	0.5
Medication: Aspirin	1.2	1.6	10.4	-0.4	0.9	-1.0	1.1	-0.9	1.4	0.2	-0.4	-1.0	-1.2	3.2	-1.3	1.5	0.7	-1.0	-1.5	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	7.8	-1.4	-2.0	-0.8	-1.4	-0.3	-0.2	-1.0	-1.7	-0.3	-1.0	-1.1	-0.5	-2.8	-1.4	-0.2	-0.0	-0.6
Breast cancer (self-reported)	1.2	1.4	5.0	-0.1	0.5	0.8	0.8	1.5	-1.6	1.8	-0.6	1.3	0.4	-0.7	0.8	-2.2	0.4	1.4	1.8	1.4
Tinnitus: Yes, now most or all of the time	1.2	1.4	4.1	-1.3	-0.6	-1.4	-1.0	-1.4	1.2	-0.3	-1.1	-1.1	-1.1	-0.2	-2.0	0.9	-1.3	-1.7	-1.2	-1.5
Verbal and Numeric Reasoning (VNR)	1.1	2.7	19.2	-1.2	-1.3	0.3	-0.7	1.4	-2.1	0.6	-1.4	1.6	-0.3	-1.4	2.1	-4.4	-1.7	1.5	1.6	0.6
Body Mass Index (BMI) (2010)	1.1	1.6	9.1	1.7	1.4	0.8	1.5	0.8	-0.1	1.4	1.5	1.0	1.6	0.6	0.4	0.8	3.0	0.9	0.2	1.0
Cardiovascular Disease	1.1	3.7	19.7	2.1	2.1	0.0	1.1	-1.3	1.9	-1.3	2.0	-1.4	-0.2	3.9	-0.8	4.4	0.2	-1.4	-2.0	-0.9
Qualifications: None of the above	1.1	2.4	8.6	1.0	0.6	1.4	1.2	2.0	-1.8	0.2	0.9	1.9	1.3	0.9	1.3	-1.1	2.9	1.9	2.0	2.1
Arm fat percentage (right)	1.1	4.3	14.5	2.6	1.8	1.8	2.6	1.5	-0.2	1.8	2.9	1.3	2.1	3.8	1.3	1.0	3.6	1.7	0.9	2.1
Medication: Cholesterol lowering	1.1	1.7	13.6	1.0	1.6	-0.2	1.0	-0.9	1.2	0.0	0.9	-0.5	-0.5	3.7	-0.4	1.5	1.7	-0.6	-1.5	-0.6
Arm fat mass (right)	1.1	4.7	18.1	2.7	2.3	1.5	2.5	1.1	0.6	1.8	3.2	0.6	2.3	4.2	1.1	2.3	3.7	1.3	0.1	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.6	1.6	1.2	1.5	1.2	1.3	-1.3	1.1	1.3	1.4	1.5	0.2	0.8	0.2	1.3	1.1	1.1	1.3
Neck or shoulder pain in last month	1.1	1.6	2.9	-1.5	-1.2	-1.7	-1.4	-1.4	1.3	-1.4	-1.6	-1.5	-1.5	0.7	-1.1	-0.3	-0.7	-1.3	-1.4	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	5.8	-1.0	-1.8	-1.6	-2.4	-1.8	1.6	-0.5	-2.0	-2.1	-0.4	-1.7	-0.5	-0.2	-0.9	-1.7	-1.6	-1.7
Mood swings	1.1	2.1	11.6	1.7	1.6	0.5	1.4	0.0	1.2	0.7	2.1	-0.4	0.9	2.6	-0.0	3.4	1.9	-0.1	-0.6	0.4
Eye problems/disorders: Cataract	1.1	1.2	2.5	1.3	1.2	1.3	1.2	1.1	-1.5	0.2	1.0	1.6	0.4	1.4	0.8	-0.3	1.4	1.0	1.1	1.2
Medication: Gliclazide	1.1	1.3	6.1	-0.5	0.0	-1.0	0.1	-1.3	1.3	-1.2	-0.6	-1.1	-1.6	2.5	-0.1	0.9	-0.1	-1.3	-1.5	-1.2
Arm fat mass (left)	1.1	4.4	19.7	2.6	2.1	1.3	2.3	0.8	0.9	1.5	3.1	0.3	2.1	4.4	1.0	2.4	3.6	1.1	-0.2	1.5
Wears glasses or contact lenses	1.1	1.3	9.0	-0.6	-1.5	0.4	-0.5	1.0	-1.6	0.1	-0.9	1.0	0.3	-1.4	0.7	-3.0	-0.1	1.0	1.4	0.7
Supplements: Calcium	1.1	1.2	2.8	1.3	0.7	1.5	0.2	1.4	-1.7	0.8	0.9	1.6	1.2	-0.3	1.2	-0.5	0.6	1.2	1.3	1.3
Impedance of whole body	1.1	5.8	10.9	-2.4	-3.0	-2.6	-2.4	-2.5	2.0	-1.8	-3.0	-2.4	-2.7	-3.3	-0.8	-1.8	-2.5	-2.5	-2.2	-2.8
Ever had hysterectomy (womb removed)	1.0	1.1	2.8	0.7	0.2	1.0	0.8	1.3	-1.6	0.2	0.2	1.6	0.5	-0.9	1.0	-1.1	1.7	1.3	1.3	1.1
Pack years adult smoking proportion	1.0	1.5	3.4	-0.6	-0.5	-1.4	0.3	-1.6	1.9	0.4	-1.0	-1.9	-1.4	0.2	-1.8	1.4	-0.4	-1.4	-1.7	-1.4
Had other major operations	1.0	1.3	4.0	2.0	1.0	1.3	1.6	0.9	-0.7	0.8	1.3	1.2	1.2	0.3	0.1	0.1	1.9	1.0	0.7	1.2
Medication: Simvastatin	1.0	1.4	14.0	0.5	0.4	-0.6	0.9	-1.2	1.2	-1.0	0.2	-0.8	-1.3	3.7	-0.3	0.9	0.3	-1.0	-1.3	-0.7
Alcohol intake versus 10 years previously	1.0	1.5	3.9	0.9	0.9	1.3	0.1	1.6	-1.1	0.3	1.4	1.2	1.7	1.5	0.9	-0.4	2.0	1.5	1.4	1.5
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	6.0	-2.3	-1.0	-1.9	-2.1	-2.2	1.8	-1.9	-2.0	-2.2	-1.8	-0.1	-1.2	0.7	-2.5	-2.3	-1.8	-2.0
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	11.3	-1.2	-2.0	-0.0	-1.4	0.5	-1.0	-0.7	-1.4	0.3	0.3	-3.4	-0.5	-1.5	-1.6	0.4	1.2	0.3
Forced vital capacity (FVC), Best measure	1.0	3.5	6.6	-1.9	-1.0	-2.0	-2.2	-2.4	2.1	-2.1	-1.6	-2.6	-1.4	-0.6	-1.7	1.2	-1.8	-2.5	-2.0	-2.2
Number of children fathered	1.0	1.2	5.4	-1.1	-1.6	-1.0	-1.1	-1.1	0.3	-0.1	-2.3	-0.9	-0.9	-1.3	-0.7	-1.3	-0.4	-1.1	-0.7	-1.0
Illnesses of father: Heart disease	1.0	1.3	4.6	2.1	2.0	1.4	1.5	0.5	-0.5	0.4	1.7	0.3	0.8	1.2	0.3	2.1	-0.0	0.2	0.6	1.0
Arm fat percentage (left)	1.0	4.1	14.7	2.5	1.8	1.6	2.7	1.3	-0.0	1.7	2.8	1.1	1.9	3.8	1.3	1.1	3.7	1.4	0.6	1.9
Handedness (chirality/laterality): Left-handed	1.0	1.2	3.8	1.5	1.8	0.9	0.7	0.2	-0.2	0.2	1.7	0.2	0.6	2.0	1.1	1.6	1.8	-0.0	0.1	0.5
High cholesterol (Self-reported)	1.0	1.7	6.3	0.6	1.5	-0.5	1.2	-1.2	1.9	-0.7	0.9	-1.2	-0.4	2.5	-0.9	2.3	0.7	-1.2	-1.8	-0.9
Depressed Affect (Nagel 2018)	0.9	1.9	5.2	2.2	1.2	1.3	1.3	1.4	-0.4	0.6	2.1	1.1	1.6	1.1	1.0	1.5	2.3	1.2	0.7	1.4
Neuroticism	0.9	2.1	5.9	2.4	1.4	1.7	1.8	1.5	-1.2	0.8	1.7	1.5	1.4	1.0	0.8	0.7	1.8	1.4	1.4	1.8
Stomach or abdominal pain in last month	0.9	1.2	4.1	0.2	-0.7	-1.1	-1.0	-1.1	1.4	-2.0	0.1	-0.8	-0.9	0.8	-1.7	0.5	0.1	-1.2	-1.6	-1.2
Weight	0.9	4.3	14.5	2.6	2.6	1.1	1.9	0.3	1.6	1.6	3.1	-0.4	2.4	3.8	0.8	3.2	3.1	0.7	-0.8	1.1
Pulse wave Arterial Stiffness index	0.9	1.1	2.7	-0.0	1.1	-1.1	-1.0	-1.2	1.4	-1.1	-0.8	-1.5	-1.0	0.4	-0.5	0.4	0.1	-1.4	-1.6	-1.4
Mouth/teeth dental problems: Loose teeth	0.9	1.0	4.9	1.4	1.9	0.3	0.6	-0.4	0.8	-0.6	1.7	-0.6	0.6	1.2	0.6	2.2	0.9	-0.4	-0.6	-0.0
Overall health rating	0.9	1.8	4.6	-0.6	-1.0	-1.9	-0.7	-1.2	2.1	-1.4	-0.5	-1.2	-1.7	2.1	-0.9	1.0	1.4	-1.1	-1.9	-1.4
Average weekly red wine intake	0.9	1.3	4.8	-2.2	-1.2	-0.8	-1.2	-0.1	-0.4	0.3	-2.1	-0.2	-0.8	-1.8	-0.1	-2.1	-1.3	-0.2	0.3	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	5.7	0.9	1.1	0.7	1.0	0.7	-0.2	0.2	1.3	0.7	0.7	2.4	0.9	0.8	1.5	0.9	0.4	0.9
Miserableness	0.9	1.5	5.3	2.2	1.1	1.3	1.2	0.9	-0.3	0.2	2.3	0.7	1.1	1.0	0.2	1.9	1.3	1.0	0.6	1.2
Hearing aid user	0.9	1.0	2.0	-0.2	-0.9	-1.3	-1.4	-1.1	1.0	-1.4	-1.2	-1.0	-1.0	1.0	-0.9	0.5	-0.5	-1.1	-1.0	-1.1
Commuting to job workplace: Public transport	0.9	1.1	3.0	-0.5	0.4	0.9	0.6	1.2	-1.4	0.9	0.0	1.3	0.8	-1.7	1.1	-1.6	0.6	1.0	1.3	1.0
Alcohol drinker status: Never	0.9	1.1	4.1	0.0	-0.1	-0.9	-0.0	-1.4	1.6	0.1	0.2	-1.4	-1.1	2.0	-0.3	1.1	0.3	-1.4	-1.6	-1.2
Basal cell carcinoma (self-reported)	0.9	1.1	4.4	-0.3	0.8	0.6	1.7	1.0	-0.8	2.1	-0.0	0.8	1.1	-1.6	0.3	-0.9	0.6	1.0	1.1	1.0
Leg fat mass (left)	0.9	3.5	14.0	2.4	2.0	0.9	1.8	0.4	1.3	1.3	2.7	-0.1	1.9	3.7	0.5	2.7	3.2	0.6	-0.6	1.0
Hypothyroidism (self reported)	0.8	1.8	4.6	0.4	0.7	0.9	1.2	2.0	-1.7	0.3	0.2	2.1	0.6	0.2	1.9	-1.6	1.2	2.0	1.8	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.1	1.4	0.8	1.3	0.9	1.3	-1.0	1.1	1.1	1.3	1.4	-0.3	1.1	-0.1	1.2	1.2	1.0	1.2
Trunk fat mass	0.8	3.3	11.4	2.3	1.8	1.1	2.0	0.7	1.1	1.9	2.6	0.1	2.1	3.1	1.2	1.8	3.4	0.9	-0.3	1.3
Waist circumference	0.8	3.1	24.1	1.4	1.1	-0.3	1.1	-0.7	2.2	0.1	1.5	-1.0	0.3	4.9	-0.4	2.9	2.6	-0.6	-1.7	-0.1
Alcohol usually taken with meals	0.8	1.4	6.1	-1.0	-1.0	0.3	-1.1	0.8	-1.4	0.2	-1.0	0.9	0.2	-2.4	1.0	-2.5	-1.4	0.8	1.1	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.9	0.5	0.1	-0.9	0.2	-1.2	1.9	-0.6	0.2	-1.4	-0.5	0.6	-2.0	1.9	-0.2	-1.1	-1.6	-1.0
Had menopause	0.8	1.1	2.2	1.3	1.2	0.9	1.5	1.2	-0.8	0.6	1.2	1.3	0.7	-0.8	1.0	-0.3	1.0	1.4	0.9	1.0
Illnesses of mother	0.8	1.0	4.0	-0.8	-2.0	-0.3	-1.1	-0.1	-0.4	-0.5	-1.0	-0.2	0.1	-1.6	-1.3	-1.9	-1.4	-0.2	0.5	-0.1
Medication: Amlodipine	0.8	1.1	10.7	0.7	1.0	0.2	0.6	0.8	0.0	1.5	1.0	0.5	-0.1	0.3	3.3	-0.8	1.2	1.1	0.3	0.6
Body fat percentage	0.8	3.0	12.1	2.3	1.4	1.1	2.0	0.8	0.6	1.5	2.5	0.5	1.7	3.3	1.0	1.4	3.5	1.0	-0.1	1.3
Whole body fat mass	0.8	3.4	12.2	2.2	1.9	1.1	2.0	0.7	1.1	1.8	2.7	0.1	2.0	3.5	1.0	2.1	3.4	0.9	-0.4	1.2
Leg fat mass (right)	0.8	3.2	11.2	2.3	1.9	1.0	1.8	0.5	1.1	1.3	2.7	0.0	1.9	3.4	0.5	2.5	3.3	0.7	-0.5	1.1
Chest pain or discomfort	0.8	1.2	3.2	-1.6	-0.1	-1.4	-0.8	-1.1	1.0	-1.3	-1.2	-0.6	-1.4	-0.1	-1.8	-0.1	-0.1	-0.9	-1.6	-1.5
Medication for cholesterol	0.8	1.2	4.6	-0.8	0.6	1.0	-0.2	0.7	-1.5	1.8	-0.6	0.9	1.0	-2.1	-0.3	-1.9	-0.9	0.6	1.1	0.7
Osteoporosis (self-reported)	0.8	1.0	5.5	0.4	-0.7	0.5	-1.0	0.9	-1.3	-0.9	0.2	1.2	-0.0	-1.3	1.6	-2.4	0.4	0.8	1.0	0.5
Medication: Blood pressure	0.8	1.6	6.0	2.2	1.3	0.9	1.3	0.8	-0.4	-0.0	1.8	0.8	0.5	2.5	1.4	2.2	1.1	0.8	0.3	0.7
Leg fat percentage (left)	0.8	2.9	10.2	2.5	1.5	1.2	1.7	0.9	0.4	1.2	2.7	0.6	1.9	3.2	0.8	1.8	3.0	1.1	0.1	1.4
Pack years of smoking	0.8	1.2	3.1	-0.4	-0.3	-1.3	0.4	-1.4	1.8	0.7	-0.9	-1.6	-1.3	0.3	-1.6	1.4	-0.3	-1.2	-1.6	-1.2
Bipolar Disorder or Schizophrenia	0.7	1.7	5.3	0.5	-0.6	1.3	-0.0	1.8	-2.1	-0.1	0.4	1.9	1.2	-1.5	0.6	-2.3	0.3	1.6	1.9	1.5
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.4	1.0	1.3	0.9	1.2	0.8	-1.0	0.1	0.9	1.6	0.1	-0.6	0.6	-0.6	1.8	1.1	0.6	0.7
Supplements: Zinc	0.7	0.8	2.2	-0.3	-0.1	0.7	0.0	1.2	-1.3	1.0	-0.2	1.1	0.9	-1.5	0.9	-0.5	0.1	1.2	1.3	1.1
Hand grip strength (right)	0.7	2.0	8.5	0.8	2.2	1.3	0.4	0.6	-0.2	2.2	1.2	-0.2	2.9	-2.6	0.4	0.9	-2.0	0.8	0.7	0.9
Impedance of arm (left)	0.7	3.1	11.2	-2.2	-2.0	-1.6	-1.2	-1.3	0.8	-1.0	-2.4	-1.1	-1.9	-3.4	0.0	-2.9	-1.8	-1.3	-0.9	-1.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.7	0.8	1.1	0.9	1.1	1.7	-1.4	0.6	0.4	1.9	0.7	0.3	1.5	-0.5	1.4	1.9	1.5	1.4
Leg fat percentage (right)	0.7	2.5	8.8	2.3	1.1	1.2	1.6	0.9	0.3	1.2	2.6	0.6	1.9	2.6	0.7	1.3	3.0	1.1	0.1	1.3
Eye problems/disorders: None of the above	0.7	0.8	8.6	-1.1	-1.2	-0.1	-0.6	0.2	-0.2	1.0	-0.9	0.1	0.5	-2.9	-0.2	-1.0	-0.0	0.3	0.1	0.0
Had major operations	0.7	0.9	3.6	-1.1	-1.0	-0.7	-1.6	0.1	-0.6	-1.4	-1.8	0.3	-0.4	-0.7	-0.6	-1.9	-0.4	0.4	0.4	-0.1
Long-standing illness, disability or infirmity	0.7	1.0	6.7	0.4	0.3	-0.5	0.3	-0.5	0.9	-0.7	0.3	-0.3	-0.9	2.6	0.2	1.7	1.9	-0.4	-1.1	-0.5
Mother’s age at death	0.7	0.9	3.8	-1.9	-1.2	-1.2	-0.5	-0.6	0.6	-0.6	-1.2	-0.6	-1.5	-0.2	-0.4	-0.2	-1.4	-0.8	-0.5	-1.0
Medication: Atorvastatin	0.7	0.9	3.9	1.0	1.7	0.1	1.1	-0.3	0.8	-0.1	1.5	-0.3	0.2	1.6	-0.3	2.0	0.5	-0.2	-0.8	-0.3
Arm fat-free mass (left)	0.7	3.4	16.8	1.9	2.4	0.4	0.9	-0.2	2.1	1.3	2.4	-1.2	1.9	3.2	0.1	4.1	2.2	0.0	-1.4	0.3
Commuting to job workplace: Cycle	0.7	0.9	7.0	-1.3	-0.1	-0.8	-0.1	-0.7	0.6	-0.3	-1.1	-0.7	-1.2	0.0	-0.7	-0.8	-2.7	-0.7	-0.5	-0.8
Arm predicted mass (left)	0.7	3.4	16.6	2.0	2.4	0.5	0.9	-0.2	2.1	1.1	2.5	-1.2	2.1	2.9	0.1	4.1	2.4	0.0	-1.3	0.4
Breast Cancer	0.6	1.4	10.4	-0.1	-0.1	0.1	-0.7	0.8	-0.5	1.5	-0.7	-0.0	0.6	-1.5	3.2	-2.3	-1.1	1.0	0.3	0.1
Coronary Artery Disease (CAD)	0.6	0.7	3.0	0.0	-0.2	-0.6	-0.6	-0.9	0.4	0.1	-1.2	-1.1	-0.3	-0.5	-0.8	0.4	-1.7	-1.4	-1.2	-0.8
Primary Biliary Cirrhosis	0.6	0.9	3.1	-1.5	-0.6	-0.8	-1.3	-0.6	0.3	-1.2	-1.2	-0.7	-0.7	-1.8	-0.5	-0.6	-1.1	-0.7	-0.4	-0.8
Ulcerative Colitis	0.6	0.9	4.8	1.2	0.6	0.1	0.3	-0.5	0.4	-0.2	0.9	-0.6	-0.2	2.2	-0.2	2.0	-1.7	-0.7	0.0	-0.6
Trunk fat percentage	0.6	2.5	10.5	2.1	1.2	0.9	1.9	0.8	0.8	1.5	2.2	0.3	1.6	2.8	1.1	0.9	3.2	0.9	-0.1	1.2
Relative age voice broke	0.6	0.9	3.7	0.3	0.1	1.0	0.2	1.0	-1.4	-0.5	0.4	1.2	0.9	-1.9	-0.1	-1.4	0.2	0.8	1.3	0.9
Mouth/teeth dental problems	0.6	0.9	4.2	-1.4	0.1	-0.6	-0.5	-0.7	0.6	0.7	-0.7	-1.0	-0.1	-1.9	-1.0	0.8	-2.1	-0.7	-0.4	-0.7
Fluid intelligence score	0.6	1.2	8.4	-0.5	-0.3	0.6	0.5	0.9	-1.4	0.2	-0.4	1.2	-0.2	-0.9	0.9	-2.9	-1.7	1.1	1.2	0.6
Impedance of arm (right)	0.6	2.7	13.2	-2.0	-2.1	-1.3	-1.1	-1.0	0.5	-0.5	-2.2	-0.8	-1.6	-3.6	0.2	-3.1	-1.7	-1.0	-0.5	-1.3
Qualifications: A levels/AS levels or equivalent	0.6	1.2	7.6	-0.9	-0.9	-0.5	-1.3	-0.0	-0.7	-0.6	-1.7	0.3	-0.7	-2.8	0.3	-1.9	-1.5	-0.1	0.1	-0.6
Asthma	0.6	1.1	4.1	-0.9	-1.6	0.2	-1.7	0.9	-1.5	-0.1	-1.2	0.8	0.2	-1.1	1.0	-2.0	-0.4	1.0	1.1	0.5
Medication: Paracetamol	0.6	1.0	9.5	-0.9	-0.4	-0.4	-0.3	0.8	-0.1	0.7	-1.1	0.3	-0.1	-3.1	0.7	-1.9	0.6	0.7	0.3	0.3
Headache pain in last month	0.6	1.1	2.2	-0.2	-1.4	-1.2	-1.1	-1.1	1.0	-1.5	-1.3	-1.0	-1.5	0.7	-1.1	0.8	-0.5	-1.1	-1.1	-1.1
Wheeze or whistling in the chest in last year	0.6	1.1	4.8	1.5	1.5	0.9	0.7	0.9	-0.6	2.2	1.0	0.8	1.3	0.0	1.4	0.5	1.0	1.0	0.4	0.8
Medication: Ibuprofen	0.6	0.7	2.7	0.8	0.9	0.8	0.0	1.1	-0.5	-0.0	1.3	0.7	0.6	0.3	0.9	1.7	0.8	1.0	0.6	0.9
Medication: Allopurinol	0.6	0.8	6.8	-1.6	-0.2	-0.5	-0.3	-0.5	0.7	-0.0	-0.5	-1.1	-0.8	0.6	0.4	-0.7	-2.6	-0.5	-0.4	-0.6
Medication: Omeprazole	0.6	0.7	5.8	-0.6	-0.5	0.2	-0.4	0.8	-0.8	-0.6	-0.1	0.8	0.6	-0.7	0.7	-2.4	0.8	0.8	0.9	0.6
Arm predicted mass (right)	0.6	3.1	16.4	1.8	2.4	0.3	0.7	-0.4	2.1	1.0	2.1	-1.4	1.8	2.8	-0.1	4.0	2.1	-0.2	-1.5	0.2
Alcohol intake frequency.	0.6	1.5	7.2	0.6	2.5	0.1	1.2	-0.4	0.9	0.8	1.4	-0.7	0.3	2.7	0.2	2.1	1.6	-0.3	-0.5	0.1
Number of full sisters	0.6	0.7	4.0	-0.3	-1.4	-0.6	-2.0	0.3	-0.5	-1.5	-0.8	0.6	0.1	-0.6	-1.1	-0.8	0.0	0.2	0.4	-0.2
Loneliness, isolation	0.6	0.8	3.0	1.4	1.1	0.7	0.9	0.6	0.1	0.7	1.2	0.4	0.4	1.7	0.3	1.4	1.4	0.5	0.1	0.8
Asthma (self-reported)	0.6	1.3	5.1	-0.8	-1.6	0.3	-1.6	0.9	-1.6	-0.0	-1.2	0.8	0.2	-1.3	1.2	-2.3	-0.4	1.0	1.1	0.5
Illnesses of father: None of the above (group 1)	0.6	0.7	3.2	-1.1	-1.3	-0.8	-1.8	-0.4	0.2	-1.1	-0.6	-0.2	-0.4	-0.8	-0.3	-1.5	0.5	-0.4	-0.4	-0.7
Ever taken oral contraceptive pill	0.6	0.6	3.0	-1.0	-1.3	-0.9	-1.0	-0.5	-0.0	-1.7	-1.1	-0.4	-0.8	-0.2	-0.6	-0.1	-0.7	-0.5	0.0	-0.6
Eye problems/disorders: Glaucoma	0.6	0.8	6.6	0.8	1.0	0.2	1.2	-0.1	0.4	-0.4	1.0	-0.2	-0.4	2.6	0.8	1.3	0.1	-0.2	-0.3	-0.1
Medication: Lisinopril	0.6	0.8	6.7	0.1	-0.9	-0.6	0.5	-0.4	0.9	-0.1	-0.2	-0.5	-0.7	2.6	-0.5	1.9	-0.5	-0.3	-0.5	-0.3
Basal metabolic rate	0.6	3.1	10.8	2.0	2.5	0.9	1.2	0.3	1.5	1.5	2.6	-0.6	2.4	2.8	0.6	3.3	2.5	0.6	-0.7	0.9
Irritability	0.6	1.0	3.9	1.9	1.6	0.3	0.8	-0.3	0.7	-0.1	1.1	-0.3	0.4	1.8	-0.3	2.0	0.4	-0.2	-0.8	-0.1
Vascular/heart problems diagnosed by doctor	0.6	1.6	7.0	-2.1	-2.1	-0.6	-1.6	-0.5	-0.3	-0.7	-1.2	-0.6	-0.5	-2.6	-1.2	-1.5	-1.4	-0.5	0.4	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	3.5	-1.5	-0.3	-0.9	-0.4	-0.5	0.1	-0.7	-1.5	0.0	-1.3	-0.6	-1.9	-1.2	-0.6	-0.5	-0.4	-0.7
Schizophrenia (2018)	0.5	1.0	4.9	-0.6	-2.0	-0.0	-1.0	0.7	-0.8	-1.5	-0.8	0.6	-0.0	-1.9	-0.0	-2.2	-0.1	0.5	0.7	0.3
Major Depression (MDD)	0.5	0.5	3.3	1.3	1.0	0.5	0.3	-0.0	0.3	0.4	0.9	-0.3	0.8	1.2	-0.3	1.8	-0.0	0.1	-0.2	0.2
Prostate Cancer	0.5	0.7	3.4	-0.7	-1.4	-0.3	-0.3	0.7	-0.7	0.2	-1.0	0.4	-0.1	-1.9	0.2	-1.7	-0.2	0.9	0.8	0.3
Sensitivity / hurt feelings	0.5	0.9	3.5	1.2	0.9	1.0	0.6	0.7	-0.6	-0.2	1.5	0.7	0.5	1.7	0.0	1.9	0.9	0.4	0.7	0.8
Leg fat-free mass (left)	0.5	2.6	6.3	1.7	2.5	1.1	1.8	0.7	0.8	1.9	2.2	0.1	2.3	2.2	0.8	2.3	2.5	1.0	-0.1	1.2
Fed-up feelings	0.5	0.8	1.7	1.3	0.5	0.8	0.8	1.0	-0.1	1.3	1.3	0.5	1.1	0.9	0.4	1.3	1.2	0.8	0.6	1.0
High blood pressure	0.5	1.4	4.6	2.1	1.9	0.8	1.4	0.7	-0.1	0.5	1.3	0.9	0.7	1.9	1.4	1.7	1.3	0.7	-0.0	0.7
Sitting height	0.5	3.5	12.8	1.8	3.4	1.0	3.6	0.2	1.7	3.1	2.4	-0.6	1.6	1.4	1.9	1.5	1.9	0.7	-0.6	1.0
High blood pressure (mother)	0.5	0.7	3.0	1.1	1.3	0.8	1.2	0.6	-0.5	0.3	0.7	0.7	0.5	0.6	1.7	0.9	0.2	0.6	0.4	0.6
Leg predicted mass (left)	0.5	2.6	6.7	1.7	2.5	1.1	1.8	0.7	0.8	1.9	2.2	0.1	2.3	2.0	0.8	2.2	2.6	1.0	-0.1	1.2
Nervous feelings	0.5	1.0	2.5	0.9	0.7	1.5	1.6	1.1	-1.3	0.2	1.2	1.2	0.6	0.3	0.9	-0.1	0.6	0.9	1.3	1.3
Hair/balding pattern: Pattern 2	0.5	0.6	3.1	-0.3	0.5	-0.5	-1.0	-0.6	0.7	-0.7	-0.2	-0.8	-0.4	1.4	-0.5	1.8	0.2	-0.7	-0.9	-0.6
Neuroticism score	0.5	1.1	3.0	1.7	0.9	1.1	1.1	0.8	-0.4	0.6	1.4	0.7	0.8	1.6	0.3	1.0	1.7	0.6	0.6	1.1
Worrier / anxious feelings	0.5	0.9	2.4	-1.0	-1.0	-1.4	-0.7	-0.9	1.5	-0.4	-0.3	-1.1	-0.9	-1.0	-1.4	-0.5	-0.3	-0.8	-1.1	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	4.2	0.0	-1.5	-0.8	-1.0	-1.0	0.9	-2.1	-0.4	-0.7	-0.9	-0.1	-0.9	0.3	-0.0	-0.8	-1.1	-1.0
Falls in the last year	0.5	0.6	2.7	1.3	0.0	-0.0	-1.0	0.4	0.3	-1.6	1.6	0.4	0.5	0.6	0.6	0.5	1.1	0.6	-0.1	0.3
Number of live births	0.5	0.7	2.6	0.1	0.4	-0.9	0.6	-0.7	1.6	-0.4	0.2	-1.1	-0.7	0.9	-0.9	1.1	-0.6	-0.9	-1.1	-0.7
Blood clot in the leg (DVT)	0.5	0.7	3.4	-1.4	-0.2	-0.8	-0.1	-0.4	-0.0	-0.9	-1.3	0.1	-1.2	-0.6	-1.9	-1.2	-0.3	-0.4	-0.3	-0.6
Gout (self-reported)	0.5	0.7	3.6	-1.7	-0.9	-0.7	-0.3	-0.6	0.6	-0.6	-0.5	-0.9	-1.2	0.4	-0.6	-0.6	-1.9	-0.4	-0.5	-0.7
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.9	-0.2	-1.4	-0.7	-0.5	-0.7	0.8	0.3	-0.6	-0.9	-0.0	0.0	-1.2	1.3	-0.9	-0.4	-0.5	-0.5
Arm fat-free mass (right)	0.5	2.6	13.3	1.6	2.2	0.2	0.5	-0.5	2.1	0.9	1.9	-1.3	1.8	2.4	-0.1	3.6	1.9	-0.2	-1.5	0.0
Pulse wave peak to peak time	0.5	0.6	1.5	-0.2	-1.1	0.8	0.7	0.9	-1.0	1.0	0.6	1.0	0.8	-0.5	0.3	-0.3	-0.2	1.1	1.2	1.1
Medication: Blood pressure	0.5	0.9	4.7	0.9	1.8	0.2	0.9	0.2	0.4	0.9	1.0	0.1	-0.3	2.2	1.5	1.6	0.5	0.3	-0.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	1.4	1.1	0.9	0.7	1.2	0.7	-0.7	1.0	0.4	0.2	0.3	0.4	0.5	1.0	-0.0	0.6	0.9	0.9
Comparative height size at age 10	0.5	2.9	11.2	-0.3	0.5	-1.5	-0.7	-2.3	3.4	1.6	-0.3	-3.4	-0.1	-1.3	0.1	1.0	-0.7	-1.9	-2.9	-1.9
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.7	1.5	0.5	0.3	0.1	-0.2	0.7	1.1	0.8	-0.6	0.9	0.8	0.6	1.6	0.7	0.1	-0.3	0.4
Hypertension (Self-reported)	0.5	1.3	5.0	2.2	1.8	0.8	1.4	0.5	-0.0	0.2	1.3	0.7	0.4	2.2	1.2	1.8	1.0	0.5	-0.2	0.5
Whole body fat-free mass	0.5	2.6	10.1	1.7	2.5	0.9	1.1	0.3	1.3	1.4	2.4	-0.6	2.3	2.3	0.4	3.2	2.1	0.5	-0.6	0.8
Leg fat-free mass (right)	0.5	2.6	6.3	1.7	2.5	1.0	1.7	0.7	0.7	1.8	2.1	0.0	2.2	2.5	0.9	2.5	2.3	1.0	-0.1	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	7.1	-1.1	0.1	-0.7	-0.9	-1.2	0.7	-1.0	-0.7	-1.2	-0.8	0.9	-0.7	0.1	-2.7	-1.4	-0.6	-0.9
Whole body water mass	0.5	2.7	10.6	1.7	2.5	0.8	1.1	0.2	1.5	1.4	2.4	-0.7	2.2	2.4	0.5	3.3	2.2	0.5	-0.8	0.8
Leg predicted mass (right)	0.5	2.7	6.7	1.7	2.5	1.0	1.7	0.7	0.8	1.7	2.2	-0.0	2.2	2.5	0.8	2.6	2.3	1.0	-0.1	1.2
Average weekly champagne plus white wine intake	0.5	0.7	2.4	0.6	-0.4	0.8	-0.1	0.8	-0.9	0.1	0.7	0.5	1.0	-0.9	0.6	-1.5	-0.9	0.9	1.2	0.9
Medication: Paracetamol	0.5	0.8	7.5	-0.6	0.2	-0.0	0.2	0.9	-0.2	0.8	-0.7	0.6	0.1	-2.7	0.6	-1.6	0.2	0.7	0.4	0.4
Heart disease (siblings)	0.5	0.6	2.2	0.2	0.0	0.7	0.4	1.1	-1.3	0.6	0.2	1.5	0.0	-0.4	0.8	-1.0	0.3	1.2	1.0	0.7
Alzheimer’s Disease (including proxy)	0.4	0.6	8.4	-0.1	0.6	-0.0	0.2	0.2	0.1	0.4	0.0	0.3	-0.1	0.1	1.0	-1.1	2.9	-0.1	-0.4	-0.0
Number of treatments/medications taken	0.4	0.8	2.5	0.8	0.5	0.7	1.0	1.2	-0.7	0.6	0.7	1.1	0.6	0.6	1.2	-0.4	1.6	1.1	0.7	1.0
Medication for hormone replacement therapy	0.4	0.4	1.8	0.5	-1.2	-0.5	0.1	-0.4	0.7	-1.0	-0.0	-0.4	-0.3	0.2	-0.1	0.9	1.4	-0.2	-0.7	-0.3
Severe depression (siblings)	0.4	0.5	1.2	0.5	0.2	0.9	0.5	0.9	-1.0	0.3	0.5	1.0	0.9	-1.1	0.3	-0.2	-0.2	0.7	0.9	0.7
Serious illness, injury or assault to yourself	0.4	0.4	1.5	0.0	0.0	0.4	0.4	1.0	-0.7	1.2	0.2	1.2	0.3	-0.7	0.1	-0.6	-0.5	1.1	0.7	0.6
Forced vital capacity (FVC)	0.4	1.7	4.4	-1.7	-0.1	-1.2	-1.6	-1.6	1.3	-1.1	-1.2	-1.7	-0.7	-0.5	-1.0	1.0	-2.1	-1.6	-1.2	-1.3
Trunk fat-free mass	0.4	2.3	9.5	1.5	2.4	0.7	0.6	0.0	1.4	1.2	2.2	-0.8	2.3	2.0	0.4	3.1	1.9	0.3	-0.8	0.6
Prospective memory result	0.4	0.4	1.9	-0.7	-1.4	-0.6	-0.9	-0.6	0.3	-0.2	-1.1	-0.7	-0.3	0.8	-0.7	-0.0	-0.2	-0.9	-0.3	-0.6
Trunk predicted mass	0.4	2.2	10.0	1.4	2.2	0.5	0.5	-0.2	1.6	1.0	2.1	-1.0	2.1	2.1	0.3	3.2	1.7	0.2	-1.1	0.4
Standing height	0.4	3.8	16.6	-0.4	0.9	-1.7	-1.1	-2.6	4.1	0.0	-0.2	-3.6	0.0	-0.6	0.1	2.3	-0.5	-2.2	-3.5	-2.1
High blood pressure (siblings)	0.4	0.6	1.8	0.6	1.2	0.8	0.6	0.6	-0.3	0.3	1.4	0.6	0.9	0.8	0.9	1.1	0.3	0.8	0.2	0.6
Exposure to tobacco smoke outside home	0.4	0.5	1.7	-0.3	-1.0	-0.7	-1.1	-0.5	0.6	-1.3	-0.4	-0.4	-0.4	-0.2	-1.0	-0.9	-0.1	-0.5	-0.8	-0.7
Heart disease (mother)	0.4	0.5	1.9	0.2	-0.1	-0.4	0.3	-0.4	0.7	-0.6	0.5	-0.0	-1.2	0.7	0.4	1.4	1.4	-0.2	-1.2	-0.5
Family relationship satisfaction	0.4	0.5	2.8	0.1	-0.0	-0.3	-1.7	-0.7	0.4	-0.5	0.1	-0.6	0.1	-0.3	-0.2	0.8	-1.5	-0.9	-0.7	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.6	-0.6	-0.9	0.2	-0.4	0.4	-0.6	0.1	-0.6	0.1	0.3	-1.6	-0.2	-0.7	-1.1	0.4	0.5	0.2
Back pain experienced in last month	0.4	0.6	1.6	-0.4	-1.2	-0.8	-0.9	-0.5	1.3	-1.3	0.0	-0.9	-0.7	0.0	-0.4	0.4	0.8	-0.6	-0.8	-0.5
Guilty feelings	0.4	0.6	1.6	0.3	-0.6	0.4	-0.9	1.1	-1.1	0.3	-0.4	0.8	0.5	0.1	1.0	-1.3	0.4	0.8	1.1	0.8
Unable to work because of sickness or disability	0.4	0.6	6.2	0.7	0.2	-0.1	0.3	0.1	0.3	0.2	0.6	0.5	-0.1	1.6	0.2	0.2	2.5	0.0	-0.2	0.2
Worry (Nagel 2018)	0.3	0.6	1.9	1.0	0.6	0.8	1.1	0.7	-0.5	0.2	1.4	1.0	0.7	0.2	0.5	0.5	1.1	0.6	0.7	0.9
Alzheimer’s Disease (in mother)	0.3	0.4	4.2	0.4	0.8	0.0	-0.4	0.3	-0.2	0.5	-0.2	0.4	0.2	-0.1	0.8	-0.8	2.1	0.1	-0.3	0.0
Mean Putamen Volume	0.3	0.3	1.0	0.1	-0.0	-0.3	-0.4	-0.5	0.7	0.3	-0.3	-0.6	0.4	-1.0	-0.7	-0.4	-0.4	-1.0	-0.7	-0.6
Rheumatoid Arthritis	0.3	0.4	1.2	-0.2	-0.3	-0.7	0.1	-1.1	0.8	-1.1	-0.7	-0.4	-0.9	-0.4	-0.7	-0.0	-0.1	-1.0	-0.9	-0.7
Height	0.3	6.7	28.1	-0.4	1.9	-2.0	-1.2	-3.4	5.3	2.3	-0.3	-4.5	0.7	-2.2	0.2	2.5	-0.7	-2.5	-4.5	-2.7
Lung FVC	0.3	1.3	3.7	-1.7	0.1	-1.0	-0.7	-1.1	0.1	-0.7	-1.9	-0.9	-1.7	-0.1	-1.4	-1.0	-1.7	-1.4	-0.5	-1.2
Relative age of first facial hair	0.3	0.5	1.9	1.0	-0.5	1.0	-0.2	0.6	-1.4	-0.6	0.2	1.0	0.6	-1.0	0.2	-0.1	-0.5	0.7	1.0	0.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.5	0.4	-0.6	-0.6	-0.0	-0.2	0.5	-1.0	-0.2	-0.4	-0.8	-0.7	-0.5	0.8	1.2	-0.4	-0.5	-0.5
Age when periods started (menarche)	0.3	0.8	2.3	0.4	0.9	1.3	0.0	1.0	-1.3	-0.1	0.2	1.2	1.5	-1.2	-0.1	-0.3	-0.4	1.0	1.0	1.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.4	0.5	0.7	0.2	0.8	0.4	-0.5	0.2	0.1	0.3	-0.4	1.2	0.9	-0.1	0.9	0.4	0.7	0.5
Hearing difficulty/problems with background noise	0.3	0.4	2.7	1.5	0.5	0.1	0.9	0.1	0.2	-0.1	0.7	0.2	-0.2	1.6	0.1	1.1	0.2	0.0	-0.2	0.1
Illnesses of siblings	0.3	0.4	1.4	-0.9	-0.8	-0.5	-0.4	-0.5	0.3	0.1	-1.2	-0.7	-0.3	-0.5	-0.7	-1.1	-0.4	-0.7	-0.2	-0.4
Father’s age at death	0.3	0.4	2.0	-1.1	0.4	-0.3	-0.6	0.1	-0.4	-1.1	-0.1	0.4	-0.6	0.4	0.6	0.0	-1.4	0.1	0.4	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.4	1.2	0.1	0.4	-0.3	-0.1	-0.2	-0.9	0.5	0.5	0.4	-0.8	-0.5	0.6	1.1	-0.2	-0.0	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	4.5	-0.1	0.1	0.0	-0.4	0.4	0.2	-0.4	0.8	-0.2	0.1	-0.1	-0.4	2.1	0.0	0.3	-0.1	0.0
Lung cancer (father)	0.3	0.4	2.7	0.8	-0.5	0.3	1.0	-0.0	-0.2	0.5	-0.3	0.1	0.1	0.5	-1.2	-0.3	1.6	0.1	-0.0	0.3
Length of working week for main job	0.3	0.4	2.9	0.4	0.8	-0.3	-0.1	-0.6	0.6	-0.1	-0.1	-0.5	-0.3	1.7	0.2	0.7	0.7	-0.5	-0.5	-0.3
Exposure to tobacco smoke at home	0.3	0.4	0.9	0.9	0.6	0.4	0.3	0.7	-0.4	0.5	0.2	0.2	1.0	-0.4	0.9	-0.8	0.8	0.7	0.6	0.7
Peak expiratory flow (PEF)	0.3	0.7	3.6	-0.4	-0.4	0.6	-0.2	0.8	-1.2	-0.0	-0.5	0.8	0.2	-1.9	0.5	-1.3	-0.8	0.6	1.1	0.6
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	4.2	0.8	-0.6	-0.3	-0.8	-0.2	0.1	-2.0	0.4	0.2	-0.2	0.7	-0.7	0.0	0.1	-0.3	-0.4	-0.5
Glaucoma (self-reported)	0.3	0.4	2.0	0.5	0.6	-0.1	1.3	0.1	0.1	-0.5	0.5	0.2	-0.7	1.4	0.8	0.3	0.9	0.2	-0.0	-0.0
Number of full brothers	0.3	0.3	1.7	0.3	-0.5	-0.4	-0.0	-0.6	0.7	-0.3	-0.0	-0.5	-0.4	1.3	-0.7	0.9	0.6	-0.5	-0.7	-0.4
Age at first live birth	0.3	0.5	2.9	-0.5	0.3	-0.1	-0.6	-0.7	0.4	0.4	-0.4	-1.0	0.0	-1.7	0.6	0.7	-1.4	-0.8	-0.6	-0.7
Age at last live birth	0.3	0.5	3.9	-0.0	0.4	0.8	0.9	0.1	-0.3	1.0	0.3	0.1	0.3	-2.0	0.9	0.2	-0.9	-0.2	0.2	0.2
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.5	1.2	0.5	0.5	0.1	0.6	-0.0	-0.2	0.9	0.3	0.7	0.5	0.0	1.1	0.8	0.7	0.2	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	0.6	0.8	0.7	0.8	0.6	-0.4	0.5	0.9	0.2	0.9	0.7	1.0	0.1	0.1	0.5	0.6	0.7
Osteoarthritis (self-reported)	0.3	0.4	1.0	-0.9	-0.5	-0.9	-0.7	-0.6	0.7	0.4	-0.8	-0.2	-0.4	-0.2	-1.0	-0.1	0.7	-0.4	-1.0	-0.7
Smoking status: Current	0.3	0.4	2.9	-0.4	-0.6	-0.4	-0.2	-0.4	0.1	0.4	-0.7	-0.7	-0.4	-1.2	-0.3	-0.6	-1.7	-0.1	-0.2	-0.5
Illnesses of father: High blood pressure	0.3	0.4	2.2	0.1	0.7	-0.3	-0.2	-0.6	0.5	-0.0	-0.2	-0.7	0.1	0.2	-0.9	1.5	-1.4	-0.5	-0.5	-0.5
Number of operations (self-reported)	0.3	0.5	3.5	-0.5	-1.0	-0.5	-0.4	0.5	-0.4	-0.8	-1.0	0.5	-0.4	-0.4	0.1	-1.9	0.7	0.8	0.5	0.1
Average weekly beer plus cider intake	0.3	0.5	2.2	0.6	-1.5	-0.1	-0.6	-0.2	0.0	-1.1	-0.7	0.1	-0.9	1.1	-0.5	0.8	0.8	-0.4	-0.3	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	3.8	-0.3	0.6	0.5	0.4	0.1	-0.5	-0.1	0.1	0.3	0.2	0.6	0.7	-1.9	-0.1	0.3	0.4	0.5
Age started oral contraceptive pill	0.3	0.4	2.3	0.1	1.5	0.0	1.0	0.4	-0.1	1.0	0.2	0.7	0.5	0.4	0.4	-0.3	1.0	0.2	0.2	0.3
Diastolic blood pressure, automated reading	0.3	1.0	3.0	-0.2	0.3	-0.7	-0.4	-1.2	1.6	-0.2	-0.3	-1.7	-0.4	1.3	-0.8	1.3	-0.8	-1.2	-1.7	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	3.2	-0.5	0.1	-0.3	-0.1	0.4	-0.1	-0.5	-0.2	0.4	0.3	-1.0	0.2	-1.8	1.4	0.5	0.3	0.2
Depression (Nagel 2018)	0.2	0.3	1.3	1.1	0.1	0.5	-0.5	0.7	-0.4	-0.1	0.4	0.7	1.1	0.1	0.3	0.1	0.2	0.5	0.4	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	4.2	-0.6	-0.9	0.3	-0.5	0.8	-1.3	-0.7	-0.7	1.0	-0.5	-0.1	0.7	-2.0	-0.5	0.3	0.7	0.1
Neuroticism (Nagel 2018)	0.2	0.6	2.0	1.4	0.0	0.4	0.7	0.3	0.1	-0.6	1.2	0.6	0.4	1.4	0.2	1.2	1.2	0.3	0.1	0.5
Alzheimer’s Disease (in father)	0.2	0.2	1.0	-0.4	0.3	0.1	0.4	-0.4	0.4	0.0	0.3	-0.5	-0.0	1.0	0.8	-0.3	0.2	-0.3	-0.4	-0.1
LDL Cholesterol	0.2	0.3	2.7	-0.7	-0.5	-0.5	-0.5	0.0	0.1	0.0	-0.7	-0.2	0.1	-1.6	-0.4	-0.8	-0.4	0.2	-0.0	-0.3
Schizophrenia (2014)	0.2	0.4	1.8	-0.3	-1.3	-0.1	-0.7	0.4	-0.4	-1.3	-0.7	0.2	0.1	-1.3	-0.2	-0.8	-0.1	0.3	0.0	0.1
Respiratory disease	0.2	0.4	1.2	0.1	-0.8	0.2	-0.7	0.4	-0.9	0.0	-0.7	0.8	-0.0	0.4	1.0	-1.1	1.0	0.6	0.4	0.3
Systolic blood pressure, automated reading	0.2	0.5	2.2	0.3	0.3	-0.3	-0.6	-0.7	0.9	-0.7	-0.0	-0.5	-0.2	1.5	-0.3	0.8	-0.3	-0.8	-1.5	-0.9
Medication: Co-codamol	0.2	0.2	0.8	-0.1	0.1	-0.5	0.4	-0.2	0.9	-0.2	0.2	-0.4	-0.8	0.9	-0.0	0.6	0.9	0.1	-0.5	-0.1
Current tobacco smoking	0.2	0.3	2.1	0.1	-0.3	-0.3	0.1	-0.4	0.4	0.6	-0.3	-0.8	-0.2	-1.0	-0.2	0.1	-1.4	-0.2	-0.3	-0.4
Taking other prescription medications	0.2	0.3	2.1	-0.1	-0.4	-0.5	0.4	0.1	0.4	0.5	-0.4	-0.0	-0.8	1.4	1.0	-0.1	0.4	0.1	-0.2	-0.1
Chronic bronchitis/emphysema (father)	0.2	0.3	0.7	-0.5	-0.4	-0.7	0.3	-0.4	0.7	-0.1	-0.5	-0.1	-0.7	0.5	-0.6	0.7	0.7	-0.1	-0.8	-0.6
Medication: Ramipril	0.2	0.3	2.7	0.4	-0.1	0.3	0.2	0.2	-0.3	-0.4	0.5	0.3	-0.4	1.7	-0.2	1.0	0.4	0.3	-0.1	0.2
Time employed in main current job	0.2	0.3	1.1	0.2	-0.9	0.5	0.3	0.3	-0.8	0.8	-0.3	0.3	0.4	-0.7	0.2	-1.0	0.1	0.5	0.5	0.3
Noisy workplace	0.2	0.2	0.8	-0.9	-0.1	-0.1	-0.6	-0.0	-0.4	0.4	-0.9	0.1	-0.0	0.2	0.5	-0.6	-0.8	0.0	0.2	-0.0
Tense / ‘highly strung’	0.2	0.3	1.9	0.4	0.5	0.0	0.1	-0.3	0.2	-0.5	0.1	-0.2	-0.2	0.9	-0.7	1.4	-0.2	-0.4	-0.5	-0.3
Loud music exposure frequency	0.2	0.2	1.3	-0.6	-0.7	-0.2	-0.3	-0.2	-0.1	-0.4	0.1	-0.2	-0.9	0.5	-0.1	1.1	-0.6	-0.2	0.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.6	-0.7	-1.3	0.0	-1.0	0.2	-0.7	-0.5	-0.5	0.2	-0.2	0.4	0.3	-0.5	-0.6	0.3	0.3	-0.0
Shortness of breath walking on level ground	0.2	0.3	1.9	-0.4	-0.3	-0.3	0.7	0.4	0.2	0.7	0.3	0.4	-0.1	0.7	-0.2	-0.5	1.4	0.5	-0.0	0.2
Emphysema/chronic bronchitis	0.2	0.2	0.8	0.9	0.2	0.5	0.6	0.3	0.0	0.5	0.9	0.2	0.4	0.2	0.4	0.0	0.3	0.6	-0.1	0.3
Supplements: Vitamin C	0.2	0.2	1.2	-0.4	-1.1	-0.3	-0.7	0.0	0.1	-0.6	-0.6	-0.4	0.2	-0.5	-0.3	0.2	-0.2	0.0	0.2	0.1
Illnesses of siblings: Diabetes	0.2	0.2	1.1	0.7	0.2	-0.1	0.5	-0.1	0.4	0.3	-0.1	-0.2	-0.6	1.1	-0.1	0.3	0.9	-0.0	-0.4	-0.0
Qualifications: nursing, teaching	0.2	0.3	1.3	0.5	-0.1	0.6	-0.0	0.7	-0.9	-0.0	0.2	1.2	-0.0	0.8	0.6	-0.9	-0.3	0.6	0.6	0.5
Commuting to job workplace: Walk	0.2	0.2	1.7	-0.2	-0.2	0.2	-0.2	0.1	-0.4	-0.7	0.4	0.5	-0.0	-1.3	0.4	-0.6	0.0	-0.3	0.3	0.0
Number of self-reported non-cancer illnesses	0.2	0.4	1.8	0.9	0.0	0.5	0.7	0.6	-0.6	-0.2	0.3	0.9	-0.2	0.8	1.1	-0.1	1.3	0.7	0.2	0.5
Fractured/broken bones in last 5 years	0.2	0.3	0.8	0.1	-0.9	0.3	0.1	0.7	-0.6	-0.7	0.3	0.6	0.4	0.1	0.6	-0.8	-0.1	0.9	0.4	0.4
Blood Red Count	0.1	1.4	7.1	0.2	1.8	-0.3	1.0	-0.7	1.4	2.7	0.9	-1.5	0.1	1.1	1.2	1.4	1.7	-0.3	-1.2	-0.4
Hair Pigment	0.1	2.0	14.7	-0.6	0.1	0.9	-0.1	1.2	-1.3	1.4	-0.8	1.1	1.5	-3.8	0.8	-2.2	1.0	1.1	1.3	1.2
Tanning	0.1	1.0	5.7	-0.9	-1.3	-0.9	-0.2	-0.8	0.9	-2.4	0.1	-0.7	-1.2	1.7	-1.0	0.9	-0.9	-0.6	-0.5	-0.6
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.0	0.5	-0.5	-0.2	-0.1	-0.3	0.5	-0.3	0.0	-0.3	-0.0	0.3	-1.0	0.2	-0.3	-0.5	-0.4	-0.3
Townsend deprivation index at recruitment	0.1	0.1	0.5	0.4	-0.2	0.2	0.7	-0.0	0.0	0.0	0.6	0.1	-0.3	0.4	-0.4	-0.2	-0.4	0.2	0.0	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.8	-0.6	0.2	-0.1	0.5	0.0	0.3	0.9	-0.2	-0.3	0.3	0.1	0.4	-0.4	-0.6	0.1	-0.0	0.1
Financial difficulties in last 2 years	0.1	0.1	0.5	-0.3	-0.3	-0.3	-0.3	-0.0	0.5	0.6	-0.2	-0.3	0.0	-0.6	0.1	-0.6	-0.7	-0.1	-0.3	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.1	0.9	-0.6	-0.5	-0.4	-0.4	-0.1	0.1	-0.2	-0.9	-0.1	0.0	-0.2	0.3	-0.8	0.2	0.1	-0.1	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	1.4	-0.3	0.4	-0.1	-0.3	0.2	-0.1	0.3	-0.5	0.6	-0.2	0.2	0.4	-0.1	1.2	0.2	-0.0	0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	1.6	0.4	0.0	0.6	-0.8	-0.5	-0.7	-0.3	0.0	0.1	0.5	0.1	-0.0	-0.2	-1.3	-0.4	0.3	-0.1
Migraine (self-reported)	0.1	0.2	1.2	0.4	-0.2	0.4	0.7	0.4	-0.3	-0.3	-0.0	0.5	0.1	-0.0	-0.1	1.1	0.1	0.3	0.3	0.4
Ever had bowel cancer screening	0.1	0.1	0.8	0.0	-0.1	-0.1	0.3	0.2	0.0	-0.9	0.3	0.7	-0.7	-0.1	0.4	-0.2	0.5	0.2	0.0	-0.0

Hub : Genes

NBEAL2

Models

Trait associations