Hub : Genes

ABCC5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0790 0.0280 5.4e-04 0.029 0.021 0.008 0.025 0.017 1.7e-04 1.2e-03 3.1e-02 4.6e-04 3.3e-03
2 GTEx Brain Cerebellum 0.1760 0.0770 8.6e-03 0.180 NA 0.073 NA 0.127 5.3e-06 NA 3.4e-03 NA 1.4e-04
3 GTEx Esophagus Gastroesophageal Junction 0.3560 0.1010 1.5e-04 -0.005 NA 0.012 NA 0.026 5.6e-01 NA 1.2e-01 NA 4.0e-02
4 GTEx Esophagus Mucosa 0.1340 0.0400 8.1e-06 0.104 NA 0.080 NA 0.088 1.9e-07 NA 4.8e-06 NA 1.8e-06
5 GTEx Esophagus Muscularis 0.1420 0.0480 5.2e-04 0.107 NA 0.115 NA 0.113 4.7e-07 NA 1.8e-07 NA 2.4e-07
6 GTEx Nerve Tibial 0.2401 0.0539 1.8e-08 0.113 NA 0.124 NA 0.114 2.1e-08 NA 4.8e-09 NA 1.9e-08
7 GTEx Skin Not Sun Exposed Suprapubic 0.1170 0.0570 6.7e-03 0.007 NA -0.004 NA 0.010 1.2e-01 NA 5.9e-01 NA 8.4e-02
8 GTEx Thyroid 0.1120 0.0360 1.1e-04 0.118 NA 0.092 NA 0.112 2.7e-09 NA 1.7e-07 NA 6.9e-09
9 GTEx Whole Blood 0.0990 0.0310 2.3e-05 0.081 NA 0.078 NA 0.079 7.0e-08 NA 1.2e-07 NA 9.9e-08
10 METSIM Adipose 0.0972 0.0298 1.8e-06 0.037 0.035 0.057 0.043 0.042 3.0e-06 4.5e-06 5.9e-09 4.1e-07 5.1e-07
11 NTR Blood 0.0765 0.0151 0.0e+00 0.111 0.090 0.108 0.103 0.108 6.2e-34 2.0e-27 6.8e-33 1.8e-31 7.4e-33
12 YFS Blood 0.2476 0.0279 0.0e+00 0.374 0.371 0.425 0.414 0.420 7.8e-131 2.2e-129 8.9e-154 6.9e-149 2.2e-151
13 TCGA Bladder Urothelial Carcinoma 0.0520 0.0290 1.1e-03 0.036 0.027 0.034 NA 0.030 5.1e-04 2.4e-03 7.0e-04 NA 1.3e-03
14 TCGA Prostate Adenocarcinoma 0.0435 0.0234 2.9e-04 0.028 0.025 0.028 NA 0.027 5.9e-04 9.8e-04 5.5e-04 NA 7.1e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.6 0.9 4.5 -2.1 -0.1 0.8 -1.1 0.5 0.8 -0.3 1.4 -0.4 0.1 -0.4 -0.1 -1.7 0.1
Bipolar Disorder or Schizophrenia 0.5 1.2 7.3 -2.7 -0.2 0.2 -0.9 -0.3 1.0 -1.4 0.5 -0.8 -0.6 -0.4 -0.4 -1.9 -0.1
Depressed Affect (Nagel 2018) 2.2 4.5 11.2 0.6 2.1 -0.2 -2.1 -1.2 -0.4 -0.3 -1.3 -2.8 -3.3 -3.1 -3.0 -2.2 -2.9
Depression (Nagel 2018) 0.3 0.5 1.8 -0.4 0.8 -0.2 -0.6 -0.6 -0.3 -0.2 -0.0 -0.5 -1.3 -0.7 -0.7 0.5 -1.3
Intelligence (Savage-Jansen 2018) 0.3 1.0 3.2 -1.8 -0.9 0.1 0.1 -1.4 -0.3 1.4 -1.1 -1.2 -0.1 -1.2 -1.0 -0.4 0.6
Neuroticism (Nagel 2018) 1.3 3.2 13.3 -0.1 0.5 -1.3 -0.5 -2.6 -1.3 -0.0 -2.7 -1.5 -3.6 -2.0 -1.8 -0.6 -1.8
Schizophrenia (2018) 0.3 0.7 3.1 -1.8 -0.3 -0.4 -0.3 -0.8 0.6 -1.5 -0.5 -0.7 -0.8 -0.2 -0.5 -1.1 -0.3
Schizophrenia vs Biploar Disorder 0.3 0.4 1.3 -0.1 -0.4 -0.3 0.9 -1.2 -0.2 -0.9 -0.7 0.8 0.3 0.7 0.4 1.0 -0.4
Worry (Nagel 2018) 1.2 2.6 11.7 0.4 1.1 -0.6 -0.7 -1.6 0.2 0.5 -1.8 -1.8 -3.4 -2.2 -2.1 -0.4 -2.0
Alzheimer’s Disease (in mother) 0.4 0.5 1.9 -1.4 -1.1 -0.1 0.4 -0.2 0.1 -0.9 -0.6 0.5 -0.5 0.6 0.6 -0.8 0.7
Alzheimer’s Disease (in father) 1.8 2.0 4.7 2.2 1.4 0.7 -1.9 1.5 2.1 -0.5 1.2 -1.4 -0.0 -1.3 -1.4 -1.5 -1.1
Alzheimer’s Disease (including proxy) 0.2 0.4 1.3 0.5 -0.5 -0.7 -0.0 0.7 0.6 -1.1 0.0 0.4 -0.1 0.6 0.4 -0.9 0.5
Crohns Disease (2017) 0.7 1.4 4.6 0.5 1.2 1.4 -1.7 0.3 -0.6 -0.1 0.0 -1.6 -1.2 -1.5 -1.2 -2.1 -0.7
Irritable Bowel Disease (IBD) 1.0 2.4 7.0 -0.7 1.5 -0.1 -1.8 -0.9 -1.3 -0.7 -1.0 -2.1 -1.9 -1.8 -1.7 -2.6 -1.4
Ulcerative Colitis (UC) 1.0 1.8 3.3 -0.9 1.3 -1.4 -1.2 -1.3 -1.3 -0.7 -1.3 -1.6 -1.7 -1.1 -1.3 -1.8 -1.4
Major Depression (MDD) 0.4 0.4 1.6 -1.0 -1.3 -0.0 0.5 -0.6 -0.2 0.5 -0.6 0.6 0.3 0.7 0.7 0.1 1.0
Reaction Time 1.0 2.0 7.6 -0.1 -1.5 0.1 0.8 0.6 0.5 -2.8 0.4 1.6 1.5 2.3 1.7 -0.2 1.8
Verbal and Numeric Reasoning (VNR) 0.3 0.8 2.5 -1.6 -0.2 -0.1 -0.6 -1.0 -0.2 0.5 -0.5 -1.3 -0.4 -1.5 -1.2 -0.9 0.0
Breast Cancer 0.1 0.3 1.4 0.4 0.9 -0.8 -0.4 0.3 0.1 -0.5 0.0 0.1 0.5 0.1 0.1 -0.2 -1.2
Ovarian Cancer 0.2 0.3 1.3 0.9 0.6 -0.3 -0.2 0.2 0.3 -1.1 -0.0 -0.6 0.3 -0.4 -0.3 -0.5 0.2
Prostate Cancer 1.8 2.5 6.2 -0.6 1.3 0.5 -1.5 -1.0 -0.9 1.1 -1.1 -2.3 -1.8 -2.5 -2.2 -1.9 -1.6
Age at First Birth 1.1 1.5 3.3 0.3 0.3 -1.1 -0.2 -1.4 -0.9 1.7 -1.5 -1.7 -0.5 -1.8 -1.6 0.9 -1.5
Bipolar Disorder (2011) 1.9 1.8 4.2 -1.0 1.5 0.2 -1.8 -0.6 0.7 0.6 0.7 -1.9 -0.7 -1.7 -1.7 -2.1 -1.9
Body Mass Index (BMI) (2010) 3.2 4.3 10.9 -0.1 -2.5 -2.5 2.6 -0.2 -1.4 -1.7 -0.1 2.5 1.4 2.5 2.7 2.0 3.3
Coronary Artery Disease (CAD) 1.3 1.6 5.6 2.1 2.4 1.1 -1.7 0.4 0.0 1.6 0.2 -0.9 -0.2 -0.5 -1.0 -0.8 -1.7
Crohns Disease (2012) 1.2 1.9 4.2 0.4 1.9 1.2 -2.1 0.1 -0.7 0.3 0.1 -1.8 -1.6 -1.4 -1.7 -2.0 -1.4
Mean Putamen Volume 4.6 5.3 10.9 0.8 3.0 1.8 -2.3 -0.0 1.9 2.3 -0.6 -2.7 -1.8 -3.1 -3.2 -2.2 -3.3
Fasting Glucose 1.3 1.5 5.1 1.2 -0.1 -1.4 -0.1 1.9 1.3 -1.0 2.2 1.1 0.8 1.1 1.2 1.1 1.0
HbA1C 0.4 0.4 1.3 1.1 0.2 0.6 -1.0 0.4 -0.6 0.7 0.1 -0.9 -0.0 -0.9 -0.8 -0.2 -0.2
HDL Cholesterol 1.7 2.9 8.2 1.1 2.5 0.6 -1.8 0.4 1.9 0.8 0.6 -1.9 0.1 -2.3 -2.1 -1.5 -2.9
LDL Cholesterol 0.3 0.5 2.0 -0.8 -0.4 1.4 -0.3 -0.2 0.5 0.6 -0.7 -0.4 -1.1 -0.4 -0.9 -0.2 -0.0
Lupus 0.4 0.6 3.3 1.8 1.0 -0.7 -0.7 1.2 0.4 0.7 0.7 -0.2 0.7 -0.0 0.1 0.1 -0.3
Neuroticism (2016) 1.4 2.0 7.1 -1.1 0.2 -0.4 0.2 -2.6 -0.9 0.1 -2.6 -1.1 -2.7 -1.1 -1.1 -0.2 -1.5
Primary Biliary Cirrhosis 0.6 0.8 2.0 0.3 1.4 0.9 -1.3 1.0 0.6 -0.3 0.9 -0.7 -0.7 -0.5 -1.1 -1.3 -0.6
Rheumatoid Arthritis 1.4 1.9 4.6 1.1 1.4 -0.7 -1.6 -0.3 -0.3 0.5 -0.3 -2.0 -1.4 -2.1 -1.7 -1.7 -1.7
Schizophrenia (2014) 0.3 0.6 5.1 -2.2 0.0 -0.0 -0.4 -0.9 -0.0 -1.2 0.1 -0.4 -0.1 -0.2 -0.2 -1.0 -0.3
Triglycerides 1.3 2.1 7.6 -1.8 -2.8 0.7 1.5 -0.3 -1.0 -1.0 -1.2 1.4 -0.2 1.6 1.4 0.8 2.2
Type 2 Diabetes (T2D) (2012) 1.6 1.9 6.2 -1.0 -0.1 1.3 0.6 -2.5 -2.0 1.7 -2.1 -0.7 -1.5 -0.8 -1.2 0.3 -0.9
Ulcerative Colitis 1.0 1.5 2.8 -1.2 1.3 -0.7 -1.4 -1.2 -1.1 -0.6 -0.9 -1.5 -1.5 -0.9 -1.5 -1.7 -1.0
Blood Eosinophil Count 2.8 21.7 57.1 3.2 5.3 0.7 -5.8 -0.1 1.0 -0.9 -0.6 -7.3 -2.5 -7.6 -7.2 -4.5 -6.3
Blood Platelet Count 7.9 91.2 225.0 1.8 11.9 4.7 -13.1 2.4 2.5 7.5 3.2 -14.7 -1.0 -15.0 -14.3 -7.6 -12.4
Blood Red Count 2.1 20.5 39.8 -2.6 -5.5 -4.1 6.2 -3.6 -4.6 -1.2 -3.2 5.1 2.9 5.8 5.0 6.3 4.2
Blood White Count 2.7 20.0 51.6 2.4 5.0 0.6 -5.5 -1.6 1.0 1.5 -1.0 -7.0 -2.8 -7.2 -6.8 -4.3 -6.2
Heel T-Score 0.8 6.0 17.7 0.9 -2.1 0.1 1.1 2.6 1.7 -2.5 2.7 2.7 4.2 3.3 3.1 -0.3 3.0
BMI 1.7 9.7 20.3 3.0 -3.2 -3.4 2.8 0.7 -0.8 -4.1 1.0 3.7 2.5 3.8 4.2 2.5 4.5
Height 0.5 10.2 51.8 2.8 3.4 0.5 -1.0 -1.8 -3.2 7.2 -2.7 -3.0 -1.1 -2.8 -3.8 1.0 -3.9
Waist Hip Ratio (WHR) 1.9 8.4 21.1 1.0 3.6 4.6 -3.8 2.8 2.7 3.6 3.4 -2.0 0.8 -2.1 -2.2 -2.8 -2.7
Systolic Blood Pressure 3.2 16.3 29.1 -2.9 -4.7 -3.6 4.7 -0.5 -0.9 -4.8 -0.6 5.4 3.3 5.0 5.3 4.9 4.6
Smoking Status 0.7 1.6 5.2 1.1 1.8 0.7 -1.6 0.7 -0.5 2.3 0.7 -1.1 0.2 -1.4 -1.3 0.6 -1.9
Allergy or Eczema 0.6 1.6 4.7 -2.2 0.7 0.5 -0.2 -1.5 -0.7 1.4 -1.7 -0.9 -1.0 -1.0 -1.3 -0.4 -2.0
Cardiovascular Disease 0.6 2.1 7.2 0.0 -0.8 -1.7 1.5 -0.3 -0.7 -2.7 -0.1 1.6 0.9 1.4 1.8 2.5 0.7
Hypothyroidism (self reported) 0.4 0.9 4.8 1.9 0.3 -2.2 0.5 -0.8 -0.3 -0.6 -1.0 0.0 -0.6 -0.1 -0.3 0.7 -0.5
Respiratory disease 0.3 0.6 1.6 -1.0 1.2 0.4 -0.6 -0.9 -1.3 0.4 -0.3 -0.3 -1.2 -0.1 -0.6 -0.3 -1.1
Type 2 Diabetes (T2D) (2018) 3.0 5.7 10.9 1.6 -2.5 -2.1 2.9 -0.6 -2.1 -2.5 -0.6 3.0 1.4 3.1 3.1 3.3 2.4
Lung FEV1/FVC ratio 0.5 2.6 10.7 1.8 -0.7 -3.3 1.2 -2.5 -1.6 -2.0 -2.3 -0.5 -0.5 -0.6 -0.1 1.0 0.2
Lung FVC 0.6 3.1 9.4 -1.5 -0.4 -3.0 1.3 -3.1 -2.6 -0.3 -2.7 0.4 -1.4 0.8 0.1 2.1 -0.3
Neuroticism 2.7 6.4 19.0 0.7 1.5 -1.6 -1.4 -2.6 -0.8 -0.0 -3.1 -3.2 -4.4 -3.7 -3.4 -1.8 -2.8
Chronotype (morning person) 0.9 2.0 11.0 3.3 1.1 -0.0 -1.3 0.2 -0.1 1.4 0.3 -1.8 0.9 -2.1 -1.4 -0.6 -1.0
Hair Pigment 0.2 5.9 14.7 -2.3 -2.7 -2.0 3.8 -2.7 -2.3 1.8 -1.9 2.3 -0.9 1.8 2.1 3.6 2.1
Tanning 0.1 0.7 2.2 0.7 -0.2 -1.3 -1.0 0.8 0.1 -1.2 0.6 -0.9 -0.2 -0.7 -0.9 -1.5 0.3
Hand grip strength (left) 0.9 2.3 6.9 0.4 1.2 0.5 -0.3 -1.4 -1.8 2.6 -1.9 -1.1 -2.6 -1.1 -1.3 0.4 -1.7
Number of treatments/medications taken 0.7 1.2 8.3 1.0 0.7 -2.1 -0.6 -0.0 -0.3 -2.9 -0.3 -0.8 -0.5 -0.8 -0.4 0.0 -0.5
Average weekly spirits intake 1.1 1.4 2.7 1.5 -0.4 -0.6 0.5 1.5 1.0 -1.6 1.5 1.3 0.7 1.4 1.5 0.7 1.0
Sensitivity / hurt feelings 1.0 1.8 6.1 -0.3 -0.9 -2.5 1.4 -1.9 -1.7 -1.1 -2.3 0.3 -1.2 0.3 0.5 -0.1 0.8
Frequency of depressed mood in last 2 weeks 1.2 1.6 4.0 -0.5 1.0 -0.4 -0.4 -2.0 -1.2 -0.0 -1.5 -1.3 -1.7 -1.4 -1.5 0.8 -2.0
Hearing difficulty/problems: Yes 0.9 1.4 4.0 1.3 0.1 0.4 0.5 1.5 1.5 0.2 2.0 1.3 1.3 1.1 1.4 1.0 0.9
Relative age of first facial hair 0.2 0.5 3.1 0.0 0.7 -0.1 -0.9 0.6 1.8 0.9 0.5 -0.1 0.1 -0.5 -0.2 -0.5 -0.4
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 2.5 1.6 0.3 -0.8 -0.3 0.1 -0.4 -0.3 -0.4 -0.8 -0.2 -0.9 -0.5 -0.6 -0.3
Ever used hormone-replacement therapy (HRT) 1.1 1.4 9.0 0.4 1.9 0.5 -0.5 -0.6 -0.0 3.0 -0.7 -1.0 0.6 -0.7 -1.0 0.4 -1.5
Ever had hysterectomy (womb removed) 1.3 1.4 4.9 1.7 0.5 0.5 -0.9 1.7 2.0 -2.2 1.6 -0.2 0.9 0.2 -0.1 -0.7 0.4
Systolic blood pressure, automated reading 4.0 11.6 21.9 -1.5 -4.1 -3.2 4.0 0.1 -1.1 -3.5 -0.5 4.5 2.9 4.1 4.7 3.9 4.5
Eye problems/disorders: Diabetes related eye disease 1.1 1.3 3.0 -0.8 -0.8 -1.5 1.0 -1.6 -1.7 -1.5 -1.3 0.6 -0.5 0.8 0.4 1.4 0.5
Angina 0.2 0.3 1.3 1.0 0.2 -1.0 -0.3 -0.0 -1.1 -0.4 0.3 -0.3 -0.8 -0.0 -0.1 0.1 -0.1
Medication for hormone replacement therapy 0.2 0.2 0.7 0.7 0.2 -0.9 0.2 -0.8 0.2 -0.2 -0.3 -0.1 0.2 0.2 0.0 0.2 0.2
Vitamin and mineral supplements 0.7 1.0 6.5 -0.3 -1.0 -1.4 0.7 0.3 -0.0 -2.5 0.4 0.9 -0.5 0.8 0.9 0.6 0.8
Supplements: Zinc 1.2 1.3 5.5 0.0 0.9 -0.3 -0.5 -1.1 -1.2 2.3 -1.3 -0.9 -0.8 -1.4 -1.0 -0.5 -1.5
Medication: Co-codamol 0.3 0.4 0.8 0.7 0.7 -0.6 -0.6 0.3 0.1 -0.4 0.4 -0.7 -0.9 -0.9 -0.5 -0.0 -0.6
Medication: Metformin 3.2 4.5 10.5 -0.0 -2.4 -1.9 3.0 -1.7 -2.3 -1.2 -1.9 2.5 -0.4 2.3 2.5 3.2 1.8
Diabetes (father) 0.7 0.9 2.4 0.1 -1.3 -0.9 1.4 -0.8 -1.5 -0.6 -1.2 0.5 -0.3 0.4 0.7 0.9 1.0
Diabetes (mother) 2.1 2.7 6.0 0.2 -2.3 -0.6 2.4 -0.9 -1.5 0.8 -1.3 2.0 0.4 1.8 1.9 2.3 2.2
Severe depression (siblings) 0.3 0.4 1.6 0.2 0.8 -0.3 -0.8 -0.6 -1.3 -0.1 -0.1 -0.7 0.3 -0.6 -0.3 -0.7 -0.5
Pack years adult smoking proportion 1.5 2.3 5.5 2.4 -0.3 0.0 -1.4 2.4 1.4 -2.3 1.5 -1.1 -0.8 -1.6 -0.6 -2.2 0.7
Impedance of leg (right) 0.6 2.7 9.6 0.1 1.1 1.5 -1.7 0.7 3.1 0.9 1.3 -1.9 -0.7 -2.3 -2.2 -1.7 -1.5
Leg fat-free mass (left) 0.8 4.3 9.8 2.1 -1.0 -2.4 2.2 -0.6 -3.1 0.0 -0.6 2.2 2.4 2.7 2.5 2.6 1.6
Trunk fat percentage 1.3 5.4 19.7 4.4 -1.8 -2.7 2.0 1.0 0.7 -2.6 1.2 2.3 2.0 1.9 2.6 1.5 3.1
Hand grip strength (right) 1.0 2.7 9.1 -1.0 0.2 -0.4 0.8 -2.0 -3.0 3.0 -2.7 -0.2 -1.9 -0.1 -0.4 1.4 -0.9
Townsend deprivation index at recruitment 0.4 0.5 2.9 1.1 -0.0 -0.2 -0.5 1.7 0.5 -0.3 1.1 -0.1 1.0 -0.1 -0.2 0.0 -0.2
Current tobacco smoking 0.3 0.5 1.7 0.3 0.5 0.3 -1.3 0.8 1.1 -0.3 0.6 -0.9 -0.0 -0.8 -0.9 -0.1 -0.7
Average weekly fortified wine intake 0.1 0.1 1.2 -1.1 -0.3 -0.0 -0.1 -0.3 0.3 0.3 -0.3 -0.2 -0.1 -0.2 -0.0 -0.3 0.2
Maternal smoking around birth 2.8 4.0 12.5 3.5 2.4 1.5 -2.3 1.7 3.0 0.9 2.3 -1.6 0.0 -1.7 -1.4 -1.7 -1.6
Fed-up feelings 1.8 3.3 7.6 2.3 1.6 -1.2 -1.5 -1.0 -0.4 -0.1 -1.0 -2.3 -2.5 -2.8 -2.3 -1.5 -2.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 1.8 -0.1 0.5 -0.8 0.3 -1.3 -1.3 -0.5 -0.5 0.1 -1.0 -0.0 -0.2 1.3 -0.8
Relative age voice broke 0.8 1.3 5.4 0.7 1.3 -0.2 -1.2 -0.3 0.1 2.3 -0.3 -1.4 -0.7 -1.6 -1.4 -0.8 -1.1
Taking other prescription medications 2.8 4.2 11.6 2.5 2.0 -2.0 -2.1 -0.5 0.0 -1.1 -0.2 -3.1 -1.5 -3.4 -2.6 -2.0 -2.3
Age when periods started (menarche) 0.1 0.3 3.5 -1.9 -0.0 0.3 0.3 -0.2 -0.3 -0.1 0.0 0.3 0.2 0.3 0.3 -0.1 -0.2
Bilateral oophorectomy (both ovaries removed) 0.8 0.9 2.7 1.5 1.2 -0.6 -0.8 1.0 1.6 -1.4 0.9 -0.2 0.2 0.3 0.1 -1.1 -0.0
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.6 7.5 0.2 -2.7 -0.3 1.6 0.7 1.0 -1.2 0.5 2.1 1.7 1.8 2.5 0.6 2.4
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 3.1 0.3 -1.2 -0.4 0.8 1.2 0.4 -0.5 1.2 1.1 1.0 1.1 1.5 1.6 1.7
Qualifications: CSEs or equivalent 0.5 0.7 2.2 0.8 -0.5 -1.2 1.5 -0.6 -1.0 -0.8 -0.2 0.8 0.2 0.5 0.9 0.8 0.7
Serious illness, injury or assault to yourself 0.5 0.6 2.4 1.5 1.2 0.0 -0.5 0.5 0.4 -1.4 0.4 -0.4 -0.0 0.1 -0.4 0.1 -1.0
High blood pressure 1.1 3.1 10.0 -0.1 -1.4 -2.5 2.1 -0.2 -1.1 -3.2 -0.6 2.2 0.3 1.8 2.2 2.0 1.3
Hayfever, allergic rhinitis or eczema 0.7 1.5 5.4 -1.9 1.1 0.4 -0.2 -1.4 -0.1 1.7 -1.5 -0.8 -0.5 -1.1 -1.3 0.4 -2.3
Multivitamins +/- minerals 1.2 1.5 6.8 -0.3 1.2 2.0 -0.8 -0.1 -0.3 2.6 -0.7 -1.2 0.2 -1.4 -1.2 -1.2 -1.2
Stomach or abdominal pain in last month 2.8 3.5 8.2 -0.5 -1.9 -1.7 2.4 -1.6 -2.9 -1.2 -0.9 2.0 -0.8 2.2 1.9 2.8 1.8
Supplements: Glucosamine 0.8 1.0 3.8 -0.9 1.2 1.9 -1.2 0.7 0.7 1.2 0.7 -0.8 0.3 -0.9 -0.8 -1.2 -0.8
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.3 0.0 0.3 -0.6 -0.4 0.8 0.5 -1.2 1.1 0.3 0.5 0.3 0.5 -0.4 0.8
Medication: Atenolol 0.3 0.4 3.7 -0.0 0.1 -0.3 -0.1 -0.5 0.1 -0.7 -0.2 -0.1 -1.9 -0.3 -0.3 -0.2 -0.2
Medication: Levothyroxine sodium 0.1 0.2 1.2 1.1 -0.3 -0.5 0.6 -0.4 0.0 -0.5 -0.5 -0.0 0.2 -0.1 -0.0 -0.1 0.4
Sitting height 0.2 1.8 14.6 0.2 0.2 -0.2 0.6 -0.7 -2.4 3.8 -0.4 0.3 0.9 0.6 0.2 1.3 -0.1
Chronic bronchitis/emphysema (father) 0.6 0.7 2.0 0.7 -0.1 0.1 0.5 0.8 0.7 -1.3 0.9 0.9 1.4 0.9 1.0 0.0 0.9
High blood pressure (mother) 1.5 2.1 5.3 -1.7 -1.0 -1.9 1.5 -2.3 -2.3 -1.2 -2.3 0.4 -1.2 0.4 0.4 0.6 0.0
Body mass index (BMI) 2.1 9.0 18.7 2.9 -2.8 -3.0 2.9 0.9 -1.0 -3.6 1.0 3.7 2.8 3.7 4.2 2.5 4.3
Impedance of leg (left) 0.8 4.0 14.8 0.1 1.2 2.1 -2.2 1.4 3.9 0.8 1.7 -2.1 -0.7 -2.6 -2.5 -2.3 -1.7
Leg predicted mass (left) 0.8 4.1 9.4 2.2 -0.9 -2.4 2.2 -0.5 -3.1 0.0 -0.6 2.2 2.4 2.6 2.5 2.5 1.6
Trunk fat mass 1.2 5.3 20.3 4.5 -1.6 -2.6 2.0 1.0 -0.1 -2.0 1.1 2.3 2.4 2.2 2.7 1.7 2.9
Waist circumference 1.3 4.8 11.1 3.3 -1.4 -1.1 1.7 1.7 0.1 -1.4 1.9 2.6 2.8 2.4 3.0 1.6 3.1
Number of incorrect matches in round 0.6 1.0 2.9 -1.1 0.5 -0.5 -0.3 -1.7 -0.7 1.1 -1.3 -0.7 -0.8 -0.7 -1.0 -1.0 -1.4
Past tobacco smoking 2.6 4.7 15.0 -1.9 -3.3 -1.8 2.6 -1.7 -0.8 -3.9 -1.9 1.6 -0.3 1.7 1.9 0.7 3.2
Alcohol usually taken with meals 1.2 1.9 8.3 -1.3 0.9 -0.2 0.5 -2.9 -0.6 2.0 -2.6 -0.6 -1.2 -0.5 -0.9 0.1 -1.3
Nervous feelings 0.7 1.3 4.5 -0.1 0.3 -1.7 0.2 -2.1 -0.5 -1.5 -2.1 -0.6 -1.5 -0.7 -0.6 0.0 -0.7
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 2.7 -0.1 0.5 -0.1 0.0 -1.5 -0.5 0.6 -1.4 -0.8 -1.6 -0.9 -1.0 0.6 -1.4
Hearing difficulty/problems with background noise 0.8 1.3 3.5 -0.2 -0.7 -0.3 1.2 0.3 0.8 -0.5 1.0 1.7 1.3 1.8 1.9 1.1 1.1
Hair/balding pattern: Pattern 2 0.8 1.0 2.3 -0.7 1.4 0.4 -1.5 -0.0 0.4 0.9 0.8 -1.1 -1.2 -0.7 -1.1 -1.1 -1.4
Had menopause 1.0 1.2 4.8 -0.1 0.5 -0.1 0.3 -2.2 -1.8 0.1 -1.8 -0.8 -1.2 -0.7 -0.9 1.4 -0.7
Had other major operations 3.4 4.1 8.7 1.1 2.0 0.5 -2.8 0.2 0.7 -0.9 -0.4 -2.9 -2.4 -2.8 -2.8 -2.7 -2.4
Forced vital capacity (FVC) 0.6 2.2 8.3 -0.8 0.3 -1.2 0.9 -2.9 -2.2 2.4 -2.2 0.0 -0.2 0.3 -0.4 1.7 -0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.7 3.6 0.8 -1.6 1.2 0.6 1.5 1.7 -0.5 1.2 1.4 1.6 1.1 1.7 0.2 1.9
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 2.2 0.7 0.4 0.5 -0.6 -0.8 -0.6 -0.7 -1.5 -1.3 -1.3 -1.2 -1.1 -0.8 -0.5
Qualifications: None of the above 0.7 1.6 7.2 1.5 -0.1 0.5 -0.6 2.7 1.5 -1.0 2.2 0.7 0.9 0.3 1.1 -0.6 1.0
Financial difficulties in last 2 years 0.3 0.4 1.2 0.8 1.1 0.8 -0.5 0.1 0.4 0.2 0.5 -0.1 0.7 0.3 -0.5 -0.3 -1.0
Mouth/teeth dental problems 0.5 0.8 5.4 -0.3 -1.0 0.5 1.0 0.4 0.2 -0.0 -0.2 1.0 2.3 0.9 0.8 0.3 1.1
Heart attack 0.3 0.4 1.7 1.3 0.2 -0.3 -0.1 0.8 0.4 -1.0 1.0 0.1 1.0 0.4 0.0 -0.3 0.6
Allergy 0.6 1.4 3.0 1.7 -0.9 -0.6 -0.1 1.7 1.1 -1.6 1.6 0.5 1.1 0.5 0.8 -0.6 1.7
Pain all over the body in last month 0.4 0.4 2.0 0.0 -0.3 -0.9 -0.1 0.0 0.2 -1.4 -0.6 -0.4 -1.3 -0.6 -0.2 -0.6 -0.2
Diabetes (self-reported) 1.3 1.9 7.0 1.6 -0.5 -2.0 1.4 -1.5 -2.6 -1.0 -1.1 0.8 -0.4 0.8 0.9 2.2 0.2
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.9 -1.1 0.3 1.7 -0.2 -1.3 0.5 1.1 -0.7 -0.8 0.3 -0.8 -1.1 -0.2 -1.0
Medication: Ramipril 1.5 1.9 4.5 0.9 -0.9 -0.5 1.0 1.1 -0.4 -1.5 1.4 1.9 0.5 2.1 2.1 1.3 1.7
Medication: Simvastatin 0.4 0.5 1.4 1.0 1.2 -0.1 -0.8 0.1 -0.9 -0.4 -0.6 -1.1 -0.1 -0.8 -0.7 -0.5 -0.8
Fluid intelligence score 0.4 0.8 2.4 -0.8 -0.4 0.0 -0.1 -1.5 -0.3 0.3 -0.9 -1.3 -0.8 -1.6 -1.2 -1.1 -0.0
Illnesses of siblings 0.8 1.1 6.9 0.4 0.6 -0.8 -1.0 -0.2 -0.5 2.6 -0.3 -1.3 -0.6 -1.3 -0.9 -0.9 -0.6
Neuroticism score 2.7 5.7 12.7 0.5 1.6 -1.6 -1.2 -2.8 -0.9 0.0 -2.9 -3.2 -3.4 -3.6 -3.3 -1.5 -2.9
Weight 1.3 6.2 10.8 3.3 -1.9 -2.5 2.6 0.4 -1.8 -1.3 0.4 3.0 3.0 3.1 3.3 2.7 3.0
Impedance of arm (right) 0.7 3.5 10.0 1.1 1.4 0.6 -1.6 -0.4 2.6 1.0 0.2 -2.5 -1.5 -3.2 -2.8 -1.9 -2.2
Arm fat percentage (right) 1.7 6.8 18.5 4.3 -2.1 -2.7 2.2 1.1 0.1 -3.2 1.2 2.8 2.8 2.5 3.3 1.2 3.6
Trunk fat-free mass 0.4 2.2 8.3 1.2 -0.0 -0.4 1.0 0.4 -2.9 1.2 -0.1 1.4 2.6 1.9 1.7 1.7 0.7
Hip circumference 1.6 7.0 15.1 2.9 -2.7 -2.9 2.9 0.4 -0.7 -2.2 0.5 3.1 2.9 3.1 3.5 2.4 3.9
Time employed in main current job 0.3 0.3 1.8 -0.2 -0.5 0.1 0.8 -0.6 -0.4 -0.8 -0.4 0.3 0.4 0.0 0.4 1.3 0.2
Alcohol intake versus 10 years previously 0.4 0.6 2.3 1.1 1.5 0.0 -0.5 -0.4 -0.6 0.1 0.3 -0.7 -0.1 -0.2 -0.9 -0.8 -1.2
Father’s age at death 0.4 0.5 2.7 -1.6 -1.0 0.9 0.5 -0.5 -0.1 0.1 -0.9 0.0 -0.7 0.2 0.3 -0.1 0.9
Worrier / anxious feelings 1.1 2.2 6.2 1.1 1.0 -0.8 -0.6 -0.9 -0.0 0.5 -1.8 -1.9 -2.5 -2.2 -2.0 -0.4 -2.0
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.7 4.0 0.6 0.7 -1.9 -0.2 -1.7 -2.0 -0.0 -1.7 -1.1 -2.0 -1.2 -1.0 0.1 -1.2
Falls in the last year 0.4 0.5 1.8 1.3 -0.5 -1.4 0.2 0.6 0.5 -1.1 0.4 -0.1 -0.2 -0.8 0.3 -0.6 0.5
Hair/balding pattern: Pattern 3 0.3 0.4 2.2 0.9 0.8 1.5 -0.1 -0.1 0.2 1.0 -0.4 -0.3 -0.9 -0.0 -0.5 -0.3 -0.4
Number of live births 2.1 2.9 8.0 0.3 -1.7 -0.3 1.5 1.4 0.0 -0.5 1.3 2.6 2.1 2.3 2.8 1.7 2.3
Forced expiratory volume in 1-second (FEV1) 0.8 2.5 10.3 -0.3 0.4 -1.7 0.9 -3.2 -2.4 2.0 -2.6 -0.4 -0.9 -0.1 -0.8 1.4 -1.1
Pulse rate 0.6 1.0 3.2 0.1 1.6 1.8 -1.0 1.0 1.0 1.2 1.0 0.0 0.3 0.7 -0.0 0.1 -1.3
Happiness 0.9 1.1 4.1 -0.9 -1.0 -0.3 0.7 -1.4 -2.0 -0.5 -1.7 -0.1 -1.4 0.0 0.2 0.9 0.2
Noisy workplace 0.3 0.3 1.3 0.5 0.9 -1.2 -0.1 -0.3 -0.5 -0.9 -0.2 0.1 -0.3 0.5 0.0 -0.6 -0.4
Qualifications: A levels/AS levels or equivalent 0.8 1.8 5.8 -2.4 -1.7 0.7 1.6 -0.6 -0.8 1.4 -0.9 1.4 0.1 1.6 1.4 1.2 1.2
Serious illness, injury or assault of a close relative in last 2 years 1.7 1.9 4.7 -0.5 -2.2 -1.6 1.7 -1.4 -1.2 -1.3 -1.4 1.2 0.6 1.4 1.5 0.3 1.9
Mouth/teeth dental problems: Dentures 1.3 2.2 5.4 1.1 1.2 0.8 -1.8 0.8 0.0 -0.5 0.6 -2.2 -1.9 -2.3 -1.9 -2.2 -0.7
Asthma 0.2 0.4 2.6 -1.6 0.4 0.6 -0.2 -0.8 -0.7 0.3 -0.1 0.1 -1.0 0.2 -0.0 -0.1 -0.6
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.8 -1.3 -0.3 0.0 0.6 -1.3 -0.7 -0.1 -1.3 0.1 -1.2 0.3 -0.4 0.9 -0.2
Medication: Cholesterol lowering 0.3 0.5 2.0 0.1 0.3 -0.7 -0.7 0.1 0.3 -0.6 -0.4 -1.0 0.3 -1.3 -0.5 -1.4 -0.7
Depression (self-reported) 0.6 0.8 2.1 0.1 0.5 0.6 -0.5 -0.8 -0.3 0.9 -0.7 -1.2 -1.4 -1.4 -1.1 -0.1 -0.7
Medication: Lansoprazole 0.7 0.8 2.4 1.4 -0.4 -1.5 0.6 0.6 -0.7 -0.5 0.9 0.8 0.6 0.6 1.1 1.3 0.9
Prospective memory result 0.6 0.8 2.9 -0.8 0.2 -0.9 0.3 -1.3 -0.8 1.5 -1.7 -0.1 -0.6 0.1 -0.3 0.8 -0.8
Lung cancer (father) 1.1 1.3 4.9 1.8 1.6 -0.0 -0.6 -0.2 -0.5 1.5 -0.0 -1.0 -0.4 -1.3 -1.4 -0.0 -2.2
Illnesses of mother 3.2 3.9 6.9 1.9 2.6 2.1 -2.6 1.0 1.6 1.9 0.5 -2.3 -0.0 -2.4 -2.4 -1.8 -2.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.8 7.8 0.3 -0.3 -2.7 1.7 -2.8 -2.5 1.8 -2.6 0.3 -0.4 0.3 0.0 2.2 -0.2
Pulse wave Arterial Stiffness index 0.2 0.2 1.5 -0.2 -0.2 -0.5 0.3 -0.3 -0.1 0.2 -0.5 0.0 0.8 -0.1 -0.2 1.2 -0.6
Impedance of arm (left) 1.1 5.1 13.2 1.4 1.6 0.7 -2.2 -0.3 3.2 1.0 0.2 -3.0 -2.3 -3.6 -3.4 -2.4 -2.4
Arm fat mass (right) 1.6 6.6 14.8 3.9 -2.0 -2.4 2.3 1.1 -0.7 -2.4 1.1 3.0 3.0 2.9 3.4 1.9 3.4
Trunk predicted mass 0.4 2.2 8.2 1.3 -0.0 -0.3 1.0 0.4 -2.9 1.3 -0.1 1.4 2.7 1.9 1.7 1.6 0.7
Standing height 0.3 2.8 20.7 0.9 1.5 0.8 -0.3 -0.9 -1.7 4.5 -1.0 -1.0 0.8 -0.7 -1.4 0.8 -2.3
Length of working week for main job 2.0 2.2 5.6 -0.7 -1.6 -0.7 1.3 0.3 -0.6 -2.1 0.2 2.2 1.0 2.1 2.4 1.0 1.9
Exposure to tobacco smoke at home 0.9 1.0 2.5 1.1 -1.1 -0.2 1.1 0.6 0.2 -0.6 0.5 1.2 0.9 0.9 1.4 1.4 1.6
Breastfed as a baby 0.7 0.8 3.4 -1.4 -0.3 -0.8 0.8 -0.9 -1.1 1.8 -0.9 0.4 -1.2 0.3 0.2 0.0 0.4
Tense / ‘highly strung’ 1.8 2.9 10.0 -2.7 -0.2 -0.7 0.3 -3.2 -0.9 -0.3 -2.7 -1.2 -2.8 -1.4 -1.5 0.0 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.9 2.9 12.7 -1.6 -0.7 -1.6 0.7 -3.3 -2.4 0.2 -3.6 -1.0 -1.5 -1.1 -0.6 -0.1 -0.4
Hair/balding pattern: Pattern 4 1.5 3.8 7.6 -0.0 -2.3 -2.5 2.1 0.3 -1.6 -2.8 0.1 2.3 1.1 2.0 2.5 2.4 2.0
Birth weight of first child 0.3 0.5 2.1 0.5 -0.8 0.1 0.9 0.7 -0.4 0.9 0.4 0.7 -0.4 0.4 0.5 1.4 0.8
Peak expiratory flow (PEF) 0.9 2.2 5.7 1.2 1.2 -1.1 0.0 -2.4 -2.2 1.3 -2.0 -1.2 -1.7 -1.2 -1.4 0.1 -1.3
Pulse wave reflection index 0.8 1.0 2.3 -0.6 -1.2 -1.5 1.1 -0.3 -1.4 -0.8 -0.9 1.0 1.1 0.8 0.9 1.4 0.4
Ever highly irritable/argumentative for 2 days 1.9 2.2 5.7 1.6 2.4 0.5 -2.0 0.1 -0.2 -0.7 0.2 -1.8 -1.8 -1.6 -1.9 -1.0 -2.2
Loud music exposure frequency 1.0 1.1 3.9 1.4 2.0 1.5 -0.8 0.3 0.7 1.2 0.9 -0.8 -0.9 -0.6 -1.3 -0.5 -0.6
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 4.0 -1.0 -1.4 -0.6 1.7 -0.4 -1.7 1.6 -0.7 1.6 0.3 2.0 1.8 1.6 1.4
Mouth/teeth dental problems: Bleeding gums 0.4 0.6 2.1 -1.2 0.7 -0.7 -0.6 -1.0 -0.2 0.7 -0.5 -0.4 -0.9 -0.3 -0.5 0.4 -1.4
Blood clot in the leg (DVT) 0.3 0.4 4.0 -0.3 0.3 2.0 0.1 -0.3 0.1 0.8 -0.1 -0.3 -0.3 -0.2 -0.3 0.4 -0.1
Medication: Paracetamol 0.1 0.2 0.8 0.5 0.1 -0.8 0.2 0.2 -0.5 -0.8 -0.1 -0.1 -0.6 -0.2 -0.0 0.9 -0.3
Headache pain in last month 1.6 2.8 8.1 -1.2 -1.0 -2.0 1.5 -2.9 -2.8 0.1 -2.7 -0.1 -1.3 -0.5 -0.2 2.0 -1.0
Medication for cholesterol, blood pressure or diabetes 0.3 0.6 1.6 -0.5 -0.5 0.5 0.9 -0.6 -1.1 1.3 -0.4 0.9 -0.2 1.1 0.5 0.7 0.6
Glaucoma (self-reported) 0.5 0.6 3.3 -1.8 -0.9 -1.1 0.1 -0.1 -0.5 -0.9 -0.6 -0.2 -0.9 -0.3 0.1 -0.3 0.6
Gout (self-reported) 0.9 1.2 2.4 -1.4 -0.6 -1.3 1.1 -1.1 -1.0 -1.6 -1.4 1.0 0.2 1.4 1.2 0.1 0.8
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 2.1 1.4 0.1 -1.0 0.3 -0.2 -0.0 -0.5 -0.4 -0.0 -0.2 -0.1 -0.1 -0.2 -0.0
Medication: Amlodipine 0.7 1.0 2.5 -0.5 -1.6 -0.4 0.9 0.9 0.4 -0.7 0.4 1.5 0.8 1.0 1.5 0.6 1.6
Medication: Ventolin 100micrograms inhaler 0.3 0.3 1.4 -0.3 1.2 -0.7 -0.8 0.2 -0.0 -0.1 0.9 -0.3 -0.1 -0.7 -0.5 -0.1 -0.7
Birth weight 0.4 0.9 3.6 0.8 -0.8 -1.9 1.3 -1.4 -1.2 1.1 -0.6 0.3 0.8 0.0 0.4 0.5 0.6
Chronic bronchitis/emphysema (mother) 0.1 0.1 1.0 -0.4 0.1 -0.3 -0.0 0.1 -0.3 0.4 0.6 -0.1 -1.0 0.0 -0.2 -0.1 -0.0
High blood pressure (siblings) 0.3 0.4 2.7 -0.1 -0.4 -0.1 0.8 -0.4 0.2 -1.6 -0.5 0.6 0.1 0.3 0.3 0.7 0.1
Forced vital capacity (FVC), Best measure 0.8 3.0 7.7 -0.5 -0.4 -2.3 2.0 -2.6 -2.3 2.2 -2.2 1.0 0.6 1.1 0.6 2.8 0.0
Body fat percentage 1.5 5.9 19.4 4.4 -1.9 -2.5 1.9 1.3 0.8 -3.0 1.5 2.4 2.5 2.1 2.8 1.3 3.3
Leg fat percentage (right) 1.8 6.6 14.3 3.4 -2.3 -2.4 2.1 1.5 0.7 -3.0 1.6 2.9 3.0 2.7 3.3 1.5 3.8
Arm fat-free mass (right) 0.8 4.0 8.4 1.7 -1.0 -1.3 1.9 0.5 -2.7 0.2 0.1 2.3 2.9 2.9 2.5 2.6 1.9
Exposure to tobacco smoke outside home 0.6 0.8 2.8 0.8 0.4 0.6 0.2 1.3 0.6 1.3 1.7 0.9 -0.1 1.0 1.2 0.5 0.6
Comparative body size at age 10 0.3 0.8 3.0 0.6 -1.0 -1.5 0.8 -0.9 -1.7 1.2 -1.2 -0.1 -0.0 0.0 0.0 0.3 0.9
Number of full brothers 1.6 2.0 5.7 -1.7 -1.5 -0.3 1.4 -0.3 -0.6 -0.9 -0.0 2.2 1.3 2.4 2.0 0.3 1.8
Worry too long after embarrassment 1.0 1.6 4.9 0.1 -0.2 -1.4 0.8 -2.1 -0.9 1.1 -2.2 -0.9 -1.8 -1.6 -1.0 0.7 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 2.0 0.1 0.5 0.7 -0.7 -0.6 -0.3 -0.0 -1.3 -1.4 -0.5 -1.0 -1.3 -0.7 -0.3
Wheeze or whistling in the chest in last year 0.6 1.1 4.0 0.8 -0.7 -1.0 0.0 1.5 0.3 -2.0 1.4 0.9 0.5 0.4 1.2 0.5 1.2
Number of children fathered 0.3 0.3 0.7 0.9 0.6 -0.5 -0.5 0.3 -0.7 0.6 -0.1 -0.5 -0.3 -0.5 -0.6 0.2 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.4 0.4 1.4 0.2 -0.9 -0.2 -0.7 1.6 -0.3 -1.1 0.0 -0.5 -1.1 -1.0 -1.1
Age at first live birth 1.6 2.8 11.8 -0.5 1.9 2.5 -1.2 -0.0 0.5 3.4 -0.2 -1.3 -0.7 -1.3 -1.9 -1.4 -2.5
Pulse wave peak to peak time 0.2 0.2 1.5 0.2 0.0 0.5 -0.2 0.3 0.0 -0.1 0.5 -0.1 -0.6 -0.1 0.1 -1.2 0.6
Health satisfaction 0.6 0.7 4.0 1.6 0.3 -1.7 -0.4 -0.0 -0.3 -2.0 -0.1 -0.1 0.4 0.2 0.4 0.0 -0.1
Shortness of breath walking on level ground 0.5 0.6 2.0 1.4 1.0 0.2 -0.6 -0.1 0.5 -1.0 -0.6 -0.6 -0.0 -0.4 -0.6 -0.6 -1.2
Qualifications: College or University degree 0.6 2.0 8.0 -1.9 -0.6 -0.1 0.3 -1.5 -1.4 2.8 -2.4 -1.1 -0.8 -1.4 -1.3 0.3 -0.7
Eye problems/disorders: None of the above 1.6 1.8 8.4 2.9 1.2 0.5 -0.9 1.5 0.8 1.6 1.4 -0.6 2.0 -0.5 -0.6 -1.3 -0.6
Mouth/teeth dental problems: Loose teeth 1.5 1.7 7.5 1.1 2.2 -0.4 -0.3 -1.0 -0.2 2.3 -0.4 -0.8 -0.5 -1.1 -1.3 0.5 -2.7
Emphysema/chronic bronchitis 0.5 0.6 2.4 0.3 -0.6 -0.8 0.7 -0.3 -1.0 -1.1 -0.1 0.7 1.5 0.6 0.8 0.3 0.8
Medication for pain relief, constipation, heartburn 0.2 0.4 1.2 -0.7 -0.9 0.8 0.1 -0.1 0.4 0.3 0.2 0.4 0.4 0.6 0.5 -0.8 1.1
Neck or shoulder pain in last month 0.6 0.8 5.1 0.1 -0.3 -2.2 0.2 -1.3 -0.1 -0.6 -0.9 -0.4 -1.1 -0.9 -0.6 0.3 -0.7
Medication: Blood pressure 0.2 0.4 4.2 0.5 -0.2 -0.4 -0.1 0.5 0.6 -2.0 0.1 0.1 -0.1 -0.0 0.2 -0.1 -0.0
Angina (self-reported) 0.3 0.3 1.7 1.3 0.5 -0.5 -0.7 0.4 -0.6 -0.4 0.7 -0.4 -0.6 -0.1 -0.3 -0.2 -0.3
Migraine (self-reported) 1.6 1.9 7.8 -1.9 0.5 -0.6 -0.0 -2.0 -0.7 1.3 -1.9 -1.1 -1.2 -1.0 -1.4 0.1 -2.8
Medication: Ibuprofen 0.4 0.5 1.0 -0.9 -0.1 0.0 0.7 -1.0 -1.0 0.1 -0.8 0.4 -0.9 0.5 -0.0 0.9 0.1
Medication: Allopurinol 0.4 0.5 2.3 -0.5 -0.1 -1.5 0.2 -0.5 -0.8 -1.5 -0.8 -0.0 0.1 0.2 0.3 -1.0 0.1
Medication: Omeprazole 2.4 2.9 8.1 2.8 2.3 -1.1 -1.8 0.1 0.6 -0.9 -0.2 -2.3 -1.1 -2.4 -2.0 -1.5 -1.6
Medication: Seretide 50 evohaler 0.6 0.7 2.0 1.3 1.3 0.2 -0.9 0.7 0.0 1.4 0.5 -0.5 -0.8 -0.4 -0.5 -1.0 -0.4
Mean time to correctly identify matches 1.2 2.2 7.0 -1.3 -1.7 0.1 1.3 0.2 -0.4 -2.2 -0.1 1.8 1.3 2.6 1.9 0.9 1.9
Heart disease (mother) 4.0 4.9 11.2 -1.5 -2.5 -3.3 2.9 -1.5 -2.4 -0.7 -1.1 2.4 0.3 2.4 2.5 2.7 2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.0 2.9 0.0 1.0 1.7 -0.3 1.6 1.0 0.6 1.5 0.7 1.5 0.8 1.0 0.0 -0.0
Whole body fat mass 1.4 5.8 17.7 4.2 -1.8 -2.6 2.2 0.8 -0.4 -2.3 0.9 2.6 2.6 2.6 3.0 1.9 3.0
Leg fat mass (right) 1.7 6.7 16.0 4.0 -2.0 -2.5 2.1 1.2 -0.1 -2.9 1.3 2.8 3.0 2.9 3.2 1.9 3.4
Arm predicted mass (right) 0.7 3.4 9.1 1.1 -0.9 -1.4 1.8 -0.1 -3.0 0.7 -0.3 2.1 2.5 2.6 2.3 2.5 1.5
Pulse rate, automated reading 2.6 8.4 26.7 1.7 2.9 3.3 -3.7 3.3 5.2 0.5 3.6 -2.6 0.3 -2.7 -2.5 -2.7 -1.8
Alcohol intake frequency. 1.2 2.9 6.4 0.1 -1.7 -1.9 2.1 -1.4 -2.5 -1.6 -1.3 1.4 0.7 1.8 2.0 1.3 2.2
Comparative height size at age 10 0.5 2.6 12.7 1.2 -0.0 -1.3 1.7 -0.8 -3.6 3.2 -1.0 1.0 0.5 1.1 0.8 1.3 -0.3
Number of full sisters 2.8 3.4 8.5 0.1 2.0 1.0 -2.9 1.6 1.4 -0.5 2.4 -2.0 -0.4 -1.9 -2.2 -2.5 -2.1
Suffer from ‘nerves’ 0.4 0.6 1.4 0.6 0.3 -1.1 0.1 -0.9 0.3 0.5 -1.2 -0.6 -1.1 -1.0 -0.9 0.6 -0.5
Overall health rating 0.9 1.9 8.0 2.2 -1.0 -1.5 0.6 0.5 0.1 -2.8 0.8 1.1 -0.0 1.2 1.4 0.7 2.0
Chest pain or discomfort 2.3 3.3 9.1 -0.7 -1.8 -1.6 1.8 -1.9 -2.4 -3.0 -1.9 1.5 -1.3 2.0 1.3 2.0 0.9
Had major operations 0.8 1.0 1.9 1.1 1.0 0.8 -1.3 1.4 1.3 0.1 1.1 -0.9 -0.7 -1.2 -0.8 -0.3 -0.8
Age at last live birth 1.3 1.9 11.9 -0.8 1.4 2.3 -0.5 0.2 -0.0 3.5 0.0 -0.2 0.6 0.1 -0.8 -0.1 -2.2
Family relationship satisfaction 0.5 0.6 4.0 0.9 2.0 0.4 -0.5 0.5 -0.7 0.8 0.1 -0.3 -0.7 0.2 -0.3 0.4 -1.1
Leg pain on walking 0.3 0.4 2.0 0.9 1.4 -0.7 -0.7 -0.3 -0.4 -0.3 0.1 -0.6 -0.1 0.0 -0.5 -0.3 -0.9
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.4 1.0 0.8 -0.9 -0.1 0.1 0.3 -1.2 0.3 -0.3 -1.2 -0.1 -0.2 0.1 -0.1
Commuting to job workplace: Car/motor vehicle 0.6 0.7 4.7 0.0 -0.4 -1.0 0.3 -0.2 -2.2 -1.1 -0.4 0.5 -0.4 0.7 0.9 0.7 0.3
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 3.3 -0.5 -0.4 -0.4 -0.5 -0.4 -1.1 1.1 -1.1 -1.3 -0.6 -1.8 -1.0 -0.9 -0.1
Medication: Aspirin 1.2 1.6 6.7 1.8 1.2 0.3 -1.3 2.3 1.3 -0.7 2.6 -0.1 1.0 -0.2 -0.1 -0.2 -0.4
Supplements: Vitamin C 0.4 0.5 4.4 0.8 1.0 -0.1 -0.3 0.1 -0.4 2.1 0.4 0.3 0.3 0.6 0.3 -0.6 0.2
Knee pain experienced in last month 0.3 0.4 0.9 1.0 -0.4 -0.5 0.5 0.6 0.4 -0.8 0.8 0.5 0.3 0.4 0.6 0.7 0.9
Hypertension (Self-reported) 1.0 2.8 10.8 0.0 -1.3 -2.6 1.9 -0.2 -1.3 -3.3 -0.6 1.8 -0.1 1.5 1.9 1.9 1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.5 5.2 13.5 3.1 3.7 0.1 -2.6 0.7 0.9 0.2 1.1 -2.8 -1.5 -2.7 -2.9 -1.5 -3.5
Illnesses of father: Heart disease 0.5 0.6 2.1 1.2 0.5 -0.1 -0.4 -0.2 0.2 -1.4 0.5 -0.8 1.4 -0.6 -0.4 -1.3 0.3
Illnesses of siblings: Diabetes 0.7 0.8 2.3 -0.5 -1.5 0.4 1.2 -0.9 -0.3 -1.4 -0.7 0.6 -0.8 0.6 0.7 0.3 1.2
Smoking status: Previous 2.0 3.1 13.1 1.5 2.7 0.9 -1.7 0.4 -0.5 3.6 0.8 -1.3 -0.2 -1.6 -1.7 -0.1 -2.9
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.1 6.0 1.6 1.9 1.6 -1.6 0.6 0.6 2.4 0.8 -1.5 0.6 -1.4 -1.5 -1.1 -1.8
Whole body fat-free mass 0.6 3.3 9.7 1.6 -0.6 -1.3 1.6 0.1 -3.1 0.8 -0.3 2.0 2.7 2.5 2.2 2.2 1.2
Leg fat-free mass (right) 0.7 3.7 9.7 1.9 -0.9 -2.0 2.0 -0.4 -3.1 0.2 -0.7 2.1 2.3 2.5 2.3 2.4 1.4
Arm fat percentage (left) 1.6 6.4 20.6 4.5 -2.1 -2.7 1.9 1.3 0.5 -3.1 1.4 2.6 2.5 2.3 3.0 1.0 3.5
Average weekly red wine intake 0.5 0.8 3.1 -0.9 0.3 -0.1 0.5 -1.7 0.7 1.8 -1.0 -0.3 -0.7 -0.7 -0.7 0.3 -0.5
Handedness (chirality/laterality): Left-handed 0.4 0.4 2.1 0.6 -0.0 1.5 0.4 0.5 0.7 -1.0 0.2 0.4 0.3 0.8 0.1 0.6 0.8
Mood swings 1.9 3.4 7.7 1.3 1.2 -1.3 -1.4 -1.4 -0.7 -1.1 -1.5 -2.7 -2.6 -2.8 -2.6 -1.5 -2.0
Loneliness, isolation 1.6 2.2 5.2 1.0 1.6 0.2 -1.5 -0.5 0.1 0.3 -0.7 -2.0 -2.2 -2.1 -2.3 -1.2 -2.0
Long-standing illness, disability or infirmity 0.6 1.0 5.2 1.8 0.4 -1.1 -0.8 0.6 0.5 -2.3 0.6 -0.7 0.0 -0.7 -0.5 -0.8 0.2
Ever had bowel cancer screening 3.7 4.3 11.8 -0.3 1.6 -2.8 -0.1 -3.4 -2.0 0.5 -2.9 -1.9 -2.5 -2.2 -2.1 -0.2 -2.4
Diabetes diagnosed by doctor 2.1 3.5 8.3 1.5 -1.3 -2.6 2.3 -1.6 -2.6 -1.1 -1.2 1.8 0.2 1.9 2.0 2.9 1.3
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.9 -0.6 -0.7 -0.1 0.2 0.5 -0.2 -0.9 0.3 0.5 -0.2 0.2 0.4 -0.2 0.5
Friendships satisfaction 1.0 1.3 6.1 -2.5 -0.6 -0.5 0.3 -1.4 -2.0 0.3 -1.7 -0.2 -1.3 -0.3 -0.2 0.3 -0.4
Qualifications: nursing, teaching 1.3 2.0 6.9 -2.1 -0.8 -1.9 1.2 -2.1 -2.6 0.4 -2.0 0.5 -0.1 0.3 0.9 0.7 0.3
Commuting to job workplace: Walk 0.5 0.6 2.2 0.8 -0.0 1.2 -0.5 1.1 1.5 0.7 1.1 0.1 0.5 0.2 0.3 -0.4 0.0
Eye problems/disorders: Cataract 0.8 1.0 2.9 -1.6 0.1 1.2 0.1 -1.3 -1.3 0.6 -1.4 -0.2 -1.7 -0.4 -0.3 0.5 -0.6
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 4.1 0.1 -0.1 -0.3 0.4 -0.9 -0.7 -0.4 -1.1 0.3 -2.0 0.1 0.1 1.0 -0.3
Medication for cholesterol 1.3 2.0 5.0 -1.2 0.4 1.0 -0.8 -0.8 -0.4 2.2 -0.9 -1.7 -2.1 -2.1 -1.9 -1.4 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 2.9 1.4 1.4 1.0 -1.0 0.5 0.8 1.7 0.5 -1.0 -0.7 -1.0 -1.3 -1.0 -1.4
Back pain experienced in last month 0.2 0.2 1.5 1.2 -0.0 -0.0 0.5 0.1 0.2 0.8 0.1 0.3 0.2 0.0 0.1 0.9 0.1
Mineral and other dietary supplements 0.6 0.9 3.8 -0.3 -0.7 -1.9 0.8 -1.4 -0.8 -0.4 -1.4 -0.2 -1.1 -0.2 -0.2 0.6 -0.5
Breast cancer (self-reported) 2.0 2.4 6.6 2.6 1.5 2.0 -1.6 1.9 2.1 -1.1 2.0 -1.1 -0.5 -1.0 -0.7 -1.4 0.2
Asthma (self-reported) 0.2 0.5 2.4 -1.6 0.5 0.5 -0.4 -0.8 -0.9 0.4 -0.2 -0.1 -1.0 -0.1 -0.3 -0.4 -0.7
Osteoporosis (self-reported) 0.4 0.5 1.8 0.4 1.1 0.6 -0.6 0.2 1.0 -0.0 0.1 -0.7 -0.2 -0.4 -0.4 -1.3 -1.0
Osteoarthritis (self-reported) 0.4 0.5 3.3 1.2 0.2 -0.3 0.3 0.1 0.4 -1.8 0.3 -0.3 0.6 0.0 -0.3 0.9 0.6
Medication: Aspirin 1.1 1.4 6.3 1.8 0.6 -0.1 -0.8 2.2 0.9 -1.4 2.5 0.3 1.2 0.2 0.3 0.1 0.2
Medication: Gliclazide 0.9 1.0 3.3 0.0 -0.9 -1.1 1.2 -0.0 -1.2 -0.2 0.1 1.6 -0.0 1.6 1.8 0.4 1.0
Illnesses of father: None of the above (group 1) 1.3 1.6 6.8 -1.2 -0.5 -0.3 1.5 -0.7 -1.5 2.6 -0.3 1.4 -1.0 1.1 1.2 1.8 0.3
Smoking status: Current 0.4 0.7 2.1 0.4 0.7 0.6 -1.4 1.0 1.4 -0.2 0.9 -0.8 0.0 -0.8 -0.8 0.0 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.7 4.6 -0.1 0.2 -1.9 1.0 -2.1 -1.9 -1.2 -1.9 -0.1 -1.4 0.1 -0.2 1.8 -0.4
Whole body water mass 0.6 3.3 9.4 1.6 -0.6 -1.2 1.6 0.1 -3.1 0.7 -0.3 2.0 2.8 2.5 2.2 2.2 1.2
Leg predicted mass (right) 0.7 3.5 9.2 1.9 -0.9 -1.9 1.9 -0.4 -3.0 0.2 -0.7 2.0 2.2 2.5 2.2 2.3 1.4
Arm fat mass (left) 1.6 6.6 16.2 4.0 -2.1 -2.6 2.2 1.1 -0.6 -2.6 1.1 2.9 2.8 2.8 3.3 1.9 3.5
Number of self-reported non-cancer illnesses 0.5 0.9 3.3 1.0 1.8 -0.7 -0.8 -0.2 -0.9 -1.2 0.0 -1.0 0.0 -1.0 -0.9 0.1 -1.6
Average weekly champagne plus white wine intake 1.9 2.7 6.0 0.8 1.2 0.6 -1.5 -1.2 0.2 2.4 -1.5 -2.3 -2.0 -2.0 -2.3 -1.3 -1.7
Miserableness 3.4 5.9 12.5 -0.8 2.1 -1.2 -1.6 -3.1 -1.9 0.0 -2.6 -3.4 -2.6 -3.3 -3.5 -1.5 -3.2
Guilty feelings 2.6 3.9 13.0 -0.7 0.2 -1.2 0.7 -2.8 -3.3 1.1 -3.2 -1.2 -3.6 -1.6 -1.3 0.6 -1.6
Wears glasses or contact lenses 0.7 0.8 2.6 1.6 1.0 -0.8 -0.3 -0.3 0.2 0.9 -0.7 -0.9 -0.9 -1.2 -0.9 -1.0 -0.3
Ever taken oral contraceptive pill 1.3 1.5 2.6 0.5 1.0 1.5 -1.6 1.4 1.4 0.7 0.7 -1.3 0.8 -1.6 -1.3 -1.4 -1.1
Hearing aid user 0.3 0.3 1.0 0.6 0.6 0.6 -0.3 0.3 0.5 -0.2 0.2 -0.7 -1.0 -0.7 -0.4 0.7 -0.3
Mother’s age at death 0.8 1.0 3.1 -0.2 1.0 1.2 -1.4 0.6 0.9 0.6 -0.4 -1.2 -0.6 -0.6 -1.5 -0.4 -1.8
Financial situation satisfaction 0.5 0.6 2.6 0.7 1.2 1.6 -0.8 0.5 0.1 -0.6 0.3 -0.5 -0.1 -0.0 -0.7 0.6 -0.8
Tinnitus: Yes, now most or all of the time 0.6 0.6 4.5 -0.7 0.7 0.4 -0.3 -0.9 0.8 0.9 -0.1 -0.3 -2.1 -0.5 -0.5 0.1 -0.7
Commuting to job workplace: Public transport 0.6 0.7 2.0 -0.6 -0.2 0.7 -0.1 -0.5 0.1 1.2 -1.2 -0.8 -1.4 -0.8 -0.8 -1.0 -0.4
Eye problems/disorders: Glaucoma 0.7 0.8 6.2 -2.5 -1.3 -0.7 0.3 -0.4 0.0 -0.9 -0.7 0.1 -0.8 -0.1 0.3 -0.2 0.8
Medication: Blood pressure 1.7 3.3 10.2 0.6 -1.7 -2.1 1.6 1.2 0.1 -3.2 0.7 2.5 1.3 2.1 2.5 1.5 1.8
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.2 0.5 0.4 -0.8 -0.9 -0.8 -0.2 -0.4 -0.4 -1.3 -1.1 -1.5 -1.3 -1.2 -1.2
Supplements: Fish oil (including cod liver oil) 0.5 0.6 2.2 -0.1 -0.4 1.5 0.1 1.1 0.5 -0.3 0.7 0.7 0.6 0.9 0.7 0.3 1.3
High cholesterol (Self-reported) 0.5 0.9 3.2 1.4 0.6 -0.3 -0.8 1.2 1.8 -1.2 1.1 -0.3 1.3 -0.4 0.1 -0.8 -0.2
Medication: Bendroflumethiazide 1.5 2.3 6.1 0.2 -0.9 -2.5 1.5 0.6 -1.0 -1.7 0.1 2.1 1.6 1.8 2.1 1.7 0.9
Medication: Paracetamol 0.2 0.4 1.6 0.5 0.1 -0.4 0.5 0.0 -0.9 -1.0 -0.0 0.5 -0.8 0.5 0.4 1.3 0.0
Medication: Lisinopril 0.5 0.7 3.0 0.7 -0.6 0.7 -0.5 0.9 1.3 -1.7 0.0 -0.5 -0.2 -0.2 -0.4 -1.4 0.1
Medication: Atorvastatin 1.1 1.3 5.0 0.5 -1.0 0.1 -0.0 1.5 2.2 -1.6 1.4 0.6 1.9 0.2 0.6 -0.5 0.9
Illnesses of father: High blood pressure 0.9 1.1 8.5 -0.2 -1.2 -1.0 0.8 -1.1 0.1 -2.9 -1.5 0.3 -0.1 0.4 0.3 -0.0 0.0
Alcohol drinker status: Never 0.3 0.3 2.2 -0.1 -0.2 -0.5 0.6 -0.4 -0.1 -1.0 -0.3 0.2 -0.4 0.3 0.3 1.5 0.2
Ever smoked 2.9 5.1 16.5 1.2 3.2 2.1 -2.9 1.6 1.1 4.1 1.7 -1.9 0.2 -1.8 -2.3 -1.4 -3.1
Basal metabolic rate 0.8 4.2 8.5 2.0 -0.9 -1.7 2.0 0.2 -2.9 0.3 -0.1 2.4 2.9 2.8 2.6 2.5 1.7
Leg fat percentage (left) 1.8 6.6 14.1 3.5 -2.3 -2.1 1.9 1.9 1.0 -3.0 1.8 2.9 2.9 2.6 3.2 1.2 3.8
Arm fat-free mass (left) 0.9 4.3 10.9 1.4 -0.8 -1.2 2.0 0.2 -2.9 0.5 -0.1 2.5 3.3 3.0 2.7 2.7 1.5
Number of operations (self-reported) 1.6 2.4 7.3 2.7 1.5 -0.1 -1.7 0.8 1.3 -0.2 -0.1 -1.9 -1.7 -2.0 -1.8 -1.9 -1.4
Average weekly beer plus cider intake 2.6 3.8 12.0 1.7 -0.2 0.9 -0.7 3.3 3.1 -1.9 3.5 1.1 2.9 0.7 1.1 -0.8 0.8
Irritability 0.5 0.9 2.3 0.7 -0.5 -1.5 0.4 -1.5 -0.3 -0.6 -1.4 -0.8 -1.1 -1.3 -0.8 -1.0 0.0
Risk taking 0.5 0.8 2.3 0.2 0.3 0.4 -1.3 1.3 0.8 0.7 0.9 -0.7 1.0 -0.7 -0.7 -1.5 -0.4
Ever had prostate specific antigen (PSA) test 2.1 2.4 5.0 1.4 1.4 1.8 -1.8 1.3 1.5 1.2 0.1 -1.6 -1.2 -2.0 -1.7 -2.2 -1.5
Fractured/broken bones in last 5 years 0.7 0.9 2.9 0.8 0.5 0.4 0.8 1.0 -0.3 0.7 0.7 1.4 0.9 1.3 0.9 1.7 0.1
Age started oral contraceptive pill 0.8 1.0 2.7 -1.6 -1.2 -0.6 1.3 -0.7 -1.2 -1.0 -1.0 0.7 -0.5 0.7 0.7 1.1 1.2
Diastolic blood pressure, automated reading 2.6 8.2 17.7 -1.1 -3.4 -2.4 2.9 0.5 -0.5 -3.7 0.6 3.5 3.5 3.1 3.9 2.5 4.2
Ever depressed for a whole week 0.7 0.9 2.1 1.2 0.8 1.0 -1.0 0.7 0.1 -0.8 -0.4 -1.5 -1.1 -1.4 -1.1 -0.6 -0.3
Unable to work because of sickness or disability 0.3 0.3 1.2 -0.2 0.2 -1.1 0.3 -0.6 -0.1 -1.0 -0.6 0.3 -0.8 0.5 0.5 0.4 -0.4
Commuting to job workplace: Cycle 1.6 1.9 4.2 -0.5 1.2 0.9 -1.4 0.4 1.6 2.1 1.3 -1.4 -0.2 -2.0 -1.8 -1.1 -1.8
Myopia 0.7 1.1 3.3 1.8 1.3 0.8 -0.7 1.6 1.0 -0.1 1.3 -0.0 1.7 -0.1 0.1 -0.6 -0.5
Vascular/heart problems diagnosed by doctor 0.5 1.3 5.3 -0.2 0.6 1.7 -1.1 -0.5 0.4 2.3 -0.2 -1.5 -0.5 -1.2 -1.5 -1.2 -0.7
Cholesterol lowering medication 1.4 2.1 5.4 2.2 0.5 0.5 -0.5 2.1 1.4 -2.3 2.3 0.8 1.5 1.1 0.9 0.4 1.0
Medication: Omeprazole (e.g. Zanprol) 2.2 2.7 8.6 2.9 2.5 -1.5 -1.5 -0.4 -0.4 0.3 -0.5 -2.2 -0.5 -2.4 -1.7 -1.0 -1.9
Pain experienced in last month 0.2 0.3 2.0 -1.4 -0.1 0.9 -0.4 -0.0 -0.0 -0.2 -0.6 -0.3 0.3 -0.1 -0.2 -0.7 0.3
Supplements: Calcium 4.1 4.5 8.2 0.1 2.3 1.0 -1.5 -1.2 -0.2 2.8 -1.2 -2.7 -2.9 -2.8 -2.9 -2.0 -2.8
Basal cell carcinoma (self-reported) 0.6 0.7 3.6 0.0 -0.1 -1.3 0.8 -1.5 -0.6 -0.8 -1.9 -0.2 -0.3 -0.4 -0.3 0.9 -0.3
Heart attack/myocardial infarction (self-reported) 0.4 0.5 2.4 1.6 0.7 0.0 -0.5 0.8 0.5 -0.7 0.9 -0.4 0.8 -0.1 -0.5 -0.6 0.2
Deep venous thrombosis (DVT) (self-reported) 0.3 0.5 4.4 -0.2 0.5 2.1 -0.2 -0.2 0.2 0.7 0.0 -0.5 -0.2 -0.5 -0.5 0.3 -0.2
Heart disease (siblings) 0.6 0.7 3.0 0.1 -0.4 -0.2 0.4 1.1 0.1 -1.7 1.0 1.2 0.6 1.1 1.0 0.7 0.5
Alcohol drinker status: Previous 0.6 0.7 1.7 -0.1 -1.3 -1.1 0.8 -0.4 -1.1 0.8 -0.8 0.6 0.3 0.7 0.8 0.6 1.2
Pack years of smoking 1.1 1.7 4.7 2.2 -0.4 -0.0 -1.0 2.1 1.1 -1.8 1.2 -0.8 -0.9 -1.3 -0.4 -1.8 0.9
Impedance of whole body 0.8 3.9 11.3 0.3 1.3 1.2 -1.8 -0.1 3.4 0.9 0.6 -2.5 -1.9 -3.0 -2.9 -2.0 -2.1
Leg fat mass (left) 1.6 6.4 15.9 4.0 -2.0 -2.4 2.1 1.4 -0.0 -2.7 1.3 2.8 2.9 2.8 3.1 1.8 3.3
Arm predicted mass (left) 1.0 4.9 11.0 1.4 -1.2 -1.6 2.3 0.2 -2.8 -0.2 -0.1 2.7 3.3 3.2 3.0 2.8 2.0