Best TWAS P=2.6e-08 · Best GWAS P=1.71e-08 conditioned to 0.0344
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MEST | 0.10 | 0.02 | lasso | 4 | 0.01 | 0.02030 | 4.8 | 5.5 | 4.8e-08 | -0.59 | 0.02 | 0.91 | FALSE |
| 2 | GTEx | Brain Cerebellum | CEP41 | 0.24 | 0.13 | enet | 20 | 0.13 | 0.00015 | -5.6 | -5.6 | 2.6e-08 | 0.77 | 0.01 | 0.96 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | MEST | 0.14 | 0.01 | enet | 56 | 0.04 | 0.00039 | 4.2 | 5.4 | 8.2e-08 | -0.26 | 0.37 | 0.32 | FALSE |