TWAS
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Traits
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Lung FEV1/FVC ratio
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chr7:120,294,932-121,729,795
Best TWAS P=2.18e-08 · Best GWAS P=1.83e-10 conditioned to 2.08e-05
120.4M
120.6M
120.8M
121M
121.2M
121.4M
121.6M
121.8M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Not Sun Exposed Suprapubic
FAM3C
0.15
0.09
lasso
7
0.1
6.2e-06
-5.2
5.6
2.2e-08
-0.47
0.15
0.82
TRUE