Hub : Genes

CEP41

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.2440	0.0840	4.3e-03	0.126	NA	0.126	NA	0.123	1.5e-04	NA	1.5e-04	NA	1.7e-04
2	GTEx	Brain Frontal Cortex BA9	0.3681	0.1050	1.2e-03	-0.011	NA	0.068	NA	0.024	8.1e-01	NA	7.0e-03	NA	7.8e-02
3	GTEx	Cells EBV-transformed lymphocytes	0.2140	0.0880	3.4e-03	0.048	NA	0.004	NA	0.004	1.1e-02	NA	2.4e-01	NA	2.3e-01
4	GTEx	Esophagus Gastroesophageal Junction	0.4030	0.0970	9.4e-05	0.002	NA	0.022	NA	0.037	2.6e-01	NA	5.5e-02	NA	1.7e-02
5	GTEx	Prostate	0.2230	0.0970	7.2e-03	0.057	NA	0.011	NA	-0.006	1.5e-02	NA	1.7e-01	NA	5.0e-01
6	GTEx	Thyroid	0.1050	0.0430	2.1e-03	0.045	NA	0.046	NA	0.062	2.1e-04	NA	1.9e-04	NA	1.6e-05
7	METSIM	Adipose	0.0698	0.0264	4.2e-04	0.016	0.013	0.018	0.016	0.009	1.8e-03	0.004	8.4e-04	0.0013	1.6e-02
8	ROSMAP	Brain Pre-frontal Cortex	0.1032	0.0377	1.2e-04	0.064	0.020	0.059	0.008	0.007	1.1e-08	0.001	4.8e-08	0.0260	3.6e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.0	1.6	7.7	2.8	-0.6	-0.2	0.4	0.7	1.5	-1.1	-0.7
Bipolar Disorder or Schizophrenia	1.1	2.6	7.8	2.8	-0.9	0.0	0.7	1.6	1.4	-1.2	-2.3
Depressed Affect (Nagel 2018)	0.4	0.8	3.1	0.9	-1.3	0.3	1.8	-0.0	-0.3	-0.1	0.6
Depression (Nagel 2018)	0.5	0.7	2.4	1.5	-0.1	-0.4	0.2	0.9	-0.2	-0.3	-1.5
Intelligence (Savage-Jansen 2018)	0.1	0.4	2.2	0.5	1.5	0.2	-0.3	0.4	-0.2	-0.4	-0.6
Neuroticism (Nagel 2018)	0.4	1.0	2.1	0.3	-1.4	-1.4	0.9	-0.7	-1.1	-0.7	0.8
Schizophrenia (2018)	0.7	1.5	5.6	1.4	-0.8	0.2	0.4	1.5	0.7	-0.9	-2.4
Schizophrenia vs Biploar Disorder	0.6	0.8	2.0	0.2	-0.0	0.5	1.4	1.1	-0.2	-0.9	-1.4
Worry (Nagel 2018)	1.6	3.4	7.2	-1.4	-2.4	-2.2	-0.4	-1.3	-2.7	-2.1	1.0
Alzheimer’s Disease (in mother)	1.5	1.8	3.4	-1.5	1.6	0.3	-1.7	-0.8	-1.1	-1.1	1.8
Alzheimer’s Disease (in father)	0.9	1.0	3.5	1.4	0.1	-0.2	1.9	0.6	0.8	-1.1	-0.3
Alzheimer’s Disease (including proxy)	0.4	0.5	1.9	-0.6	1.4	0.3	-0.6	-0.1	-0.2	-0.9	0.9
Crohns Disease (2017)	0.2	0.4	1.5	0.7	0.4	-1.2	-0.6	-0.0	0.8	0.5	-0.2
Irritable Bowel Disease (IBD)	0.4	0.9	2.6	-0.9	0.2	-1.6	-1.0	-0.9	-0.3	-0.8	1.0
Ulcerative Colitis (UC)	0.7	1.4	2.7	-1.6	-0.5	-1.4	-0.7	-1.1	-0.9	-1.6	1.1
Major Depression (MDD)	0.7	0.9	2.5	0.9	-0.0	0.4	1.1	1.1	0.6	-1.1	-1.6
Reaction Time	0.7	1.3	4.0	-1.1	0.7	1.1	-1.4	0.3	-0.8	2.0	0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.2	-0.6	0.9	-1.1	-1.0	-0.5	-0.8	-0.6	0.3
Breast Cancer	0.4	1.0	2.9	-0.2	1.6	-0.7	0.0	-1.7	0.2	1.3	-0.5
Ovarian Cancer	0.3	0.4	1.4	-0.6	0.9	-0.2	-0.3	0.3	-0.4	0.7	1.2
Prostate Cancer	0.4	0.5	0.9	-0.9	1.0	0.0	0.2	1.0	-0.4	-0.7	-0.8
Age at First Birth	0.1	0.2	0.7	0.5	0.2	-0.3	0.1	0.1	-0.2	-0.8	0.7
Bipolar Disorder (2011)	0.4	0.4	2.1	0.0	0.0	-0.7	-0.5	-0.1	0.3	0.0	1.4
Body Mass Index (BMI) (2010)	1.1	1.5	3.0	1.3	-0.7	1.7	1.5	0.9	1.5	-0.1	-1.3
Coronary Artery Disease (CAD)	1.2	1.5	9.5	0.6	3.1	-0.1	-0.7	1.1	-0.1	0.0	0.5
Crohns Disease (2012)	0.7	1.1	3.9	-0.8	-0.6	-0.2	-1.3	-0.7	-2.0	-1.3	-0.1
Mean Putamen Volume	0.2	0.2	0.7	-0.8	-0.5	0.1	-0.2	-0.7	-0.6	-0.1	0.3
Fasting Glucose	1.2	1.4	7.8	0.9	0.6	2.8	1.2	-0.4	-0.4	-0.1	0.4
HbA1C	1.0	1.2	3.4	0.6	-1.7	0.8	0.6	-0.5	1.8	0.6	1.1
HDL Cholesterol	0.3	0.5	1.7	-1.3	-0.7	0.5	0.5	0.0	-0.0	0.1	1.0
LDL Cholesterol	0.7	1.2	2.6	1.0	1.3	0.4	0.9	0.3	1.6	1.3	-1.1
Lupus	0.7	1.0	2.3	1.2	-1.5	-0.8	0.8	1.0	1.1	0.9	-0.1
Neuroticism (2016)	1.7	2.5	6.5	-1.4	-1.0	-1.4	-1.0	-1.4	-2.5	-2.1	1.1
Primary Biliary Cirrhosis	1.9	2.7	6.1	-1.6	0.2	-0.4	-2.2	-2.5	-1.7	-0.5	2.2
Rheumatoid Arthritis	0.9	1.3	2.4	-0.6	-1.4	-0.9	0.3	-1.5	-1.1	-1.0	1.5
Schizophrenia (2014)	0.7	1.5	5.1	2.0	0.5	0.2	0.4	0.8	0.9	-1.2	-2.2
Triglycerides	1.4	2.2	5.3	2.3	1.0	1.9	1.3	0.8	1.2	0.1	-2.1
Type 2 Diabetes (T2D) (2012)	2.0	2.3	8.0	2.8	1.3	-0.0	1.2	-0.3	2.4	0.8	-0.9
Ulcerative Colitis	0.6	0.9	2.9	-1.7	-0.5	0.1	-0.2	-0.7	-1.2	-0.9	1.2
Blood Eosinophil Count	0.2	1.4	5.5	-1.1	1.3	-1.3	-0.0	-2.3	-1.0	0.2	0.2
Blood Platelet Count	0.1	1.0	4.4	0.4	0.7	1.0	2.1	0.2	1.5	0.3	-0.2
Blood Red Count	0.4	4.2	13.0	0.5	2.5	3.6	-1.7	1.9	-1.3	2.0	-1.1
Blood White Count	0.2	1.5	6.9	0.5	2.6	1.7	0.4	1.2	-0.3	0.3	-0.3
Heel T-Score	0.6	5.1	11.9	-3.5	1.9	0.0	-2.6	-2.5	-2.7	-0.5	2.2
BMI	3.5	20.1	34.9	5.8	-0.1	3.2	5.9	4.2	5.0	4.0	-4.8
Height	0.2	3.5	14.3	-0.5	-0.5	-3.3	0.7	-3.8	-0.2	-0.4	1.2
Waist Hip Ratio (WHR)	3.1	13.8	25.7	-5.1	0.3	-5.0	-4.1	-3.8	-4.8	-1.7	1.8
Systolic Blood Pressure	1.0	4.8	11.3	3.2	3.4	2.3	-0.5	2.0	1.5	1.4	-1.9
Smoking Status	2.0	4.8	11.4	2.9	2.5	1.9	-0.0	3.4	1.7	1.2	-2.1
Allergy or Eczema	0.7	1.8	4.2	-1.3	-0.0	1.9	-1.1	-1.6	-0.5	0.9	2.0
Cardiovascular Disease	3.8	12.5	32.4	5.7	0.9	2.5	1.7	2.1	5.5	2.6	-4.0
Hypothyroidism (self reported)	0.1	0.3	1.0	0.3	1.0	-0.1	0.4	-0.5	-0.1	0.5	0.7
Respiratory disease	0.5	1.0	3.4	-0.8	-0.9	-0.5	0.1	-1.3	-1.8	-0.4	1.1
Type 2 Diabetes (T2D) (2018)	2.5	4.6	11.8	3.4	1.0	1.2	2.5	1.4	2.2	0.9	-3.0
Lung FEV1/FVC ratio	3.0	15.1	31.0	-5.6	-1.9	-3.6	-3.8	-5.0	-4.0	-1.5	4.0
Lung FVC	0.3	1.6	4.4	-1.7	-0.1	0.9	-2.1	-0.1	-0.4	0.9	1.9
Neuroticism	0.4	1.1	1.9	-0.2	-0.8	-1.3	1.1	-1.4	-1.1	-1.2	0.6
Chronotype (morning person)	0.2	0.6	2.0	0.9	0.1	-0.3	-0.0	1.4	0.9	-0.2	0.8
Hair Pigment	0.0	1.2	3.3	-0.8	0.9	0.1	-1.8	-1.2	-0.6	0.9	-1.6
Tanning	0.3	3.2	12.3	2.4	-0.1	-1.7	0.4	1.9	0.8	0.1	-3.5
Hand grip strength (left)	0.2	0.6	1.0	-0.5	-0.6	0.9	0.6	-1.0	-0.4	-0.9	0.9
Number of treatments/medications taken	0.7	1.3	4.8	2.2	1.4	-0.9	-0.6	0.4	1.0	1.3	-0.3
Average weekly spirits intake	2.3	2.9	10.7	1.2	3.3	1.2	-0.5	-0.0	0.0	2.8	-1.0
Sensitivity / hurt feelings	0.4	0.7	1.9	1.1	1.4	-0.2	1.1	-0.5	0.5	-0.3	0.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.2	0.9	-0.1	-0.7	1.1	0.0	-0.7	-0.6	0.0
Hearing difficulty/problems: Yes	0.3	0.5	2.4	-0.2	0.2	-0.9	0.2	0.5	0.1	1.5	0.4
Relative age of first facial hair	0.9	1.9	6.4	-1.9	0.5	-0.5	-1.1	-2.5	-1.5	-0.2	1.0
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	4.6	-0.1	2.1	-0.2	-0.2	-0.9	-1.3	-1.2	0.3
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.9	1.3	0.5	1.4	1.2	0.1	0.2	-0.2	-0.2
Ever had hysterectomy (womb removed)	0.3	0.4	1.3	-0.1	-1.0	1.2	0.2	-0.4	0.2	0.4	0.2
Systolic blood pressure, automated reading	2.0	5.9	12.3	3.5	2.4	2.1	0.6	3.1	2.6	2.0	-1.8
Eye problems/disorders: Diabetes related eye disease	3.5	3.8	8.8	3.0	0.1	1.1	2.4	2.4	2.0	0.4	-2.2
Angina	3.3	4.3	15.7	2.4	2.4	1.8	-0.5	0.9	0.8	4.0	-1.6
Medication for hormone replacement therapy	1.0	1.1	2.3	1.3	-0.1	-0.1	1.5	1.4	0.1	-0.6	-1.5
Vitamin and mineral supplements	1.8	2.5	6.8	1.6	-1.2	1.7	1.6	1.1	2.6	1.0	-1.3
Supplements: Zinc	1.4	1.5	3.5	-1.1	0.7	-1.6	-1.2	-1.9	-1.3	-0.9	0.4
Medication: Co-codamol	1.0	1.2	3.0	-1.1	-0.9	-0.7	-1.7	-0.8	-1.6	-0.5	0.5
Medication: Metformin	2.8	3.9	7.4	2.7	-0.3	1.8	2.2	2.0	1.9	1.9	-2.2
Diabetes (father)	1.3	1.6	5.3	1.9	-0.7	0.3	2.3	-0.4	0.3	-1.0	-1.5
Diabetes (mother)	1.7	2.1	6.3	2.5	1.0	-0.0	0.2	0.4	0.8	2.2	-2.0
Severe depression (siblings)	0.4	0.4	1.8	0.3	0.2	0.8	-0.2	1.3	-0.3	-0.3	0.6
Pack years adult smoking proportion	1.6	2.5	4.8	2.2	1.3	-1.2	1.1	1.7	1.8	2.0	-0.9
Impedance of leg (right)	2.5	11.9	24.3	-4.4	-0.4	-1.3	-4.3	-4.0	-4.9	-3.3	2.4
Leg fat-free mass (left)	1.8	9.5	19.6	4.0	0.1	0.8	4.4	2.3	4.4	2.5	-3.0
Trunk fat percentage	1.0	4.0	9.6	2.2	-1.0	1.6	3.1	1.3	3.0	0.2	-2.0
Hand grip strength (right)	0.3	0.7	2.5	-0.8	-0.3	-0.3	0.9	-1.0	-0.7	-0.4	1.6
Townsend deprivation index at recruitment	0.3	0.5	1.4	0.8	-0.2	0.5	0.3	0.9	0.5	1.2	0.2
Current tobacco smoking	1.3	2.2	7.6	1.0	2.8	1.2	-1.1	1.2	0.6	1.3	-1.6
Average weekly fortified wine intake	0.2	0.3	0.6	-0.4	-0.6	-0.3	-0.2	-0.7	-0.8	-0.5	-0.4
Maternal smoking around birth	0.5	0.7	1.7	0.5	0.5	0.7	0.8	0.8	1.0	1.3	-1.0
Fed-up feelings	0.4	0.8	2.8	-0.2	-1.2	-0.4	1.7	-0.3	-1.1	-0.7	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	4.1	2.0	0.5	-0.2	0.8	0.7	0.0	-0.6	-1.1
Relative age voice broke	0.4	0.6	1.7	-0.2	1.0	1.3	-0.1	-0.4	1.0	0.9	0.2
Taking other prescription medications	0.4	0.7	2.5	1.6	0.4	-1.5	0.2	0.1	0.0	0.3	0.3
Age when periods started (menarche)	0.4	0.8	4.7	0.3	0.2	1.2	-0.0	2.2	0.0	0.6	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.4	-0.1	0.1	0.3	1.5	0.5	0.3	0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.3	-1.1	-0.4	0.7	-0.3	0.3	0.2	0.7	-0.6
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	5.6	0.0	-2.4	-0.2	1.0	0.9	0.7	-0.9	0.2
Qualifications: CSEs or equivalent	0.4	0.5	1.6	-0.3	-0.3	-1.1	0.1	-0.8	0.2	1.3	-0.8
Serious illness, injury or assault to yourself	0.2	0.2	0.8	0.1	-0.3	-0.9	0.2	0.3	0.4	0.6	0.5
High blood pressure	3.2	8.8	32.1	5.7	1.0	1.0	1.0	2.7	4.7	1.4	-2.0
Hayfever, allergic rhinitis or eczema	1.2	2.5	4.9	-1.8	0.5	0.9	-1.9	-2.0	-1.9	0.1	2.2
Multivitamins +/- minerals	1.0	1.3	3.7	-1.5	0.1	-0.6	-1.4	-0.9	-1.9	-0.7	1.0
Stomach or abdominal pain in last month	0.3	0.4	2.1	-0.4	-1.5	-0.1	-0.8	0.2	-0.1	0.1	0.6
Supplements: Glucosamine	1.4	1.8	4.9	-1.2	2.2	1.9	-0.9	0.1	-1.0	1.7	0.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	5.0	-0.7	1.3	-0.1	-1.2	-0.6	-2.2	-1.0	-0.4
Medication: Atenolol	2.0	2.5	8.7	3.0	1.6	-0.2	0.4	1.0	2.3	0.5	-1.5
Medication: Levothyroxine sodium	1.1	1.8	3.1	1.8	1.7	0.6	1.6	0.3	1.7	1.6	-0.1
Sitting height	0.1	1.0	3.4	1.4	0.7	-1.2	-0.4	-0.7	0.0	-0.3	-1.9
Chronic bronchitis/emphysema (father)	0.2	0.3	1.0	0.9	1.0	0.1	0.1	0.1	-0.2	0.6	-0.2
High blood pressure (mother)	0.5	0.8	2.0	0.5	0.2	0.9	-0.5	0.4	1.2	1.1	-1.4
Body mass index (BMI)	2.8	12.1	20.8	4.3	0.2	3.1	4.6	3.2	4.5	3.0	-2.8
Impedance of leg (left)	2.7	13.3	27.2	-4.6	-0.7	-1.6	-4.6	-3.9	-5.2	-3.4	2.5
Leg predicted mass (left)	1.7	9.1	18.8	3.9	0.2	0.8	4.3	2.2	4.3	2.4	-2.9
Trunk fat mass	1.4	6.0	14.7	2.8	-0.8	1.6	3.8	1.4	3.6	1.1	-2.4
Waist circumference	0.2	0.7	2.1	0.6	-0.5	-0.2	1.5	0.3	1.1	0.6	-1.2
Number of incorrect matches in round	0.8	1.3	3.2	1.4	-0.5	-0.6	0.3	1.6	1.8	1.2	-0.5
Past tobacco smoking	1.2	2.2	6.7	-2.6	-0.4	-1.2	-0.1	-2.5	-1.3	-0.9	0.6
Alcohol usually taken with meals	0.6	1.0	2.5	-1.1	0.5	0.4	0.3	-1.2	-1.6	0.6	1.4
Nervous feelings	1.3	2.5	6.8	-0.8	-2.6	-1.5	-0.5	-0.7	-2.6	-1.6	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.8	1.3	-0.8	-1.3	1.1	0.9	-0.0	0.3	-0.9
Hearing difficulty/problems with background noise	0.4	0.6	1.6	0.1	1.0	0.0	-0.4	-0.7	-0.6	1.3	1.0
Hair/balding pattern: Pattern 2	2.8	3.6	10.0	-1.7	-0.2	-2.1	-0.4	-3.2	-0.6	-2.2	2.4
Had menopause	0.9	1.1	3.2	-0.4	0.7	-0.2	-0.6	-1.8	-0.6	-1.1	1.8
Had other major operations	0.2	0.2	0.8	-0.1	-0.5	-0.9	-0.2	0.6	-0.1	0.1	0.6
Forced vital capacity (FVC)	0.6	2.5	7.7	-2.8	-1.6	-1.2	-1.0	-2.0	-1.0	-0.2	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.6	-1.6	-0.7	0.9	-0.6	0.3	-0.3	0.0	0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.0	-0.3	1.0	-0.3	-0.5	-0.8	-0.2	0.4	0.1
Qualifications: None of the above	0.5	1.0	3.3	-1.8	-0.7	-0.9	-0.3	-0.2	-1.1	-0.3	1.4
Financial difficulties in last 2 years	0.9	1.3	3.0	0.6	-1.7	-1.4	-0.2	0.9	-0.0	1.7	-1.0
Mouth/teeth dental problems	0.5	0.8	1.7	-1.1	1.1	1.2	-0.7	-0.2	-1.3	0.6	-0.2
Heart attack	0.4	0.5	1.7	0.8	0.4	-1.3	-0.3	0.6	-0.4	1.0	0.2
Allergy	0.9	2.1	4.5	1.5	-0.1	1.1	1.7	1.7	2.1	0.5	-1.7
Pain all over the body in last month	1.7	1.8	6.0	1.2	-1.6	-1.2	0.7	2.5	0.9	0.1	-1.3
Diabetes (self-reported)	2.1	3.3	8.3	2.9	0.1	1.0	1.6	0.6	2.0	2.2	-2.4
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	5.1	-2.2	0.1	0.0	-2.2	-2.3	-1.8	0.3	2.2
Medication: Ramipril	1.6	2.1	3.7	1.4	1.4	1.9	-1.8	0.2	1.7	1.8	0.1
Medication: Simvastatin	1.9	2.8	6.1	2.4	2.3	0.6	0.7	0.9	1.9	2.5	-0.3
Fluid intelligence score	0.3	0.6	2.0	-0.8	0.6	-0.8	-0.2	0.3	-1.0	-1.4	0.4
Illnesses of siblings	0.5	0.7	3.0	-0.6	-1.7	0.1	1.2	-0.3	0.8	-0.0	-0.5
Neuroticism score	0.7	1.5	3.2	-0.5	-1.3	-1.3	0.8	-1.3	-1.8	-1.4	0.9
Weight	1.9	9.4	19.4	3.8	-0.5	1.7	4.4	2.2	4.3	2.6	-2.8
Impedance of arm (right)	2.4	11.2	20.6	-4.1	-0.8	-2.6	-3.6	-3.6	-3.0	-4.5	3.1
Arm fat percentage (right)	1.3	5.3	12.7	2.5	-0.1	2.2	3.4	1.6	3.6	1.4	-1.5
Trunk fat-free mass	0.7	3.9	8.4	2.3	0.5	0.4	2.8	0.8	2.2	2.9	-1.9
Hip circumference	1.0	4.4	12.4	2.3	-1.3	2.0	3.5	1.5	2.6	0.6	-1.6
Time employed in main current job	0.4	0.4	0.9	-0.7	0.7	0.6	-0.2	-0.7	-0.5	-1.0	0.7
Alcohol intake versus 10 years previously	0.6	0.8	2.4	1.1	-1.5	-1.4	0.2	-0.3	0.5	-0.2	-0.8
Father’s age at death	1.2	1.6	5.0	-2.2	-0.7	-0.6	-1.8	-1.1	-0.7	-1.0	1.1
Worrier / anxious feelings	2.2	4.1	10.2	-3.0	-1.5	-1.9	-1.0	-1.1	-3.2	-1.6	1.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.5	0.9	-0.4	-1.6	1.4	0.3	0.4	-0.3	-0.6
Falls in the last year	0.3	0.4	1.5	0.7	-0.4	-0.1	0.6	-0.1	1.2	0.6	-0.7
Hair/balding pattern: Pattern 3	1.1	1.6	6.3	0.3	-0.9	2.5	0.4	1.8	0.8	1.1	-0.7
Number of live births	0.4	0.6	2.4	0.1	0.0	0.6	1.5	1.0	0.9	-0.1	-0.6
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	13.0	-3.6	-2.2	-1.4	-1.4	-3.0	-1.2	-0.5	2.2
Pulse rate	0.8	1.4	3.5	1.7	1.4	0.7	-0.1	1.4	1.9	0.7	-0.2
Happiness	0.3	0.4	1.2	-1.0	-0.1	-1.1	-0.5	-0.3	-0.1	0.6	0.0
Noisy workplace	0.4	0.5	1.5	1.1	0.4	-0.2	-0.2	0.4	1.2	1.1	0.0
Qualifications: A levels/AS levels or equivalent	1.0	2.3	4.1	-1.1	1.4	-2.0	-1.6	-1.6	-1.0	-1.8	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.7	2.0	5.1	-2.2	-0.4	1.9	-2.3	-0.5	-1.1	0.5	0.6
Mouth/teeth dental problems: Dentures	0.5	0.8	2.5	0.7	-1.6	-0.9	-0.6	0.3	1.1	1.0	-0.1
Asthma	1.4	2.7	6.5	-1.4	-1.1	-1.7	-1.0	-1.9	-2.5	-1.0	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.7	-0.8	0.5	-0.3	-0.6	-0.7	-0.3	-0.8	-0.4
Medication: Cholesterol lowering	1.2	1.9	8.7	1.2	2.9	0.4	-0.7	0.0	0.6	1.7	-1.0
Depression (self-reported)	0.7	0.8	2.3	0.1	-1.2	0.3	-1.5	0.1	-1.2	0.1	-1.1
Medication: Lansoprazole	0.8	0.9	4.1	0.3	2.0	-0.1	-0.5	0.3	-1.1	1.3	0.3
Prospective memory result	0.4	0.5	2.0	0.2	-0.7	0.6	0.7	-0.9	1.4	-0.2	-0.2
Lung cancer (father)	0.5	0.6	2.1	0.0	0.7	1.5	0.4	0.9	0.7	0.5	-0.4
Illnesses of mother	0.9	1.1	3.0	0.1	-1.6	-1.6	0.2	0.1	0.3	-1.7	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	5.4	-2.3	-1.7	-0.0	-1.0	-1.7	-0.7	0.5	1.4
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	-0.2	0.6	0.4	-0.8	0.8	0.0	1.1	-1.2
Impedance of arm (left)	2.1	9.7	24.9	-3.4	-0.7	-3.0	-3.1	-3.3	-2.7	-5.0	2.0
Arm fat mass (right)	2.3	9.5	20.2	3.7	-0.1	2.3	4.5	2.4	4.3	2.5	-2.5
Trunk predicted mass	0.7	3.9	8.6	2.2	0.5	0.5	2.8	0.8	2.2	2.9	-1.9
Standing height	0.2	1.6	6.6	-0.4	-1.3	-2.6	0.3	-1.9	0.2	-0.6	-0.5
Length of working week for main job	0.5	0.6	2.6	-0.6	-0.3	0.7	0.3	0.1	0.2	1.1	-1.6
Exposure to tobacco smoke at home	0.3	0.3	0.9	-0.7	-0.2	0.0	-0.4	-0.6	-0.3	-0.9	0.4
Breastfed as a baby	1.2	1.5	3.9	-1.2	-0.2	-0.9	-1.0	-2.0	-1.5	-0.5	1.5
Tense / ‘highly strung’	1.0	1.6	4.1	-0.1	-1.6	-2.0	-0.2	-0.9	-1.6	-1.8	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	1.2	0.1	-0.3	-0.3	-0.2	-0.3	-0.5	1.1	0.4
Hair/balding pattern: Pattern 4	0.2	0.6	2.9	-0.8	-0.2	-0.3	-1.7	-0.8	-0.5	-0.3	0.0
Birth weight of first child	0.5	0.8	2.4	0.1	1.6	-0.6	-1.0	-0.1	0.5	1.0	-1.2
Peak expiratory flow (PEF)	0.9	2.1	5.8	-2.4	-2.2	-0.3	-0.6	-1.9	-0.9	1.1	0.8
Pulse wave reflection index	1.1	1.3	5.4	0.2	0.9	0.9	0.9	1.3	0.2	2.3	-1.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	0.4	0.6	0.1	0.4	-0.1	0.5	0.3	-0.4
Loud music exposure frequency	0.1	0.1	0.3	0.1	-0.5	0.4	-0.5	0.0	0.1	0.4	-0.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.3	1.5	0.7	1.1	0.7	1.0	1.1	0.1	-0.7
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	2.1	1.5	-0.8	-1.2	1.4	1.0	1.3	-1.4	-1.0
Blood clot in the leg (DVT)	0.4	0.6	1.3	-1.1	-1.0	-1.0	-0.9	-0.2	-0.0	-0.3	0.7
Medication: Paracetamol	0.2	0.3	1.9	-0.1	-0.1	0.4	-0.1	-0.1	0.3	1.4	0.7
Headache pain in last month	0.4	0.7	3.7	-0.9	-0.5	0.8	0.5	-0.3	-0.0	1.9	0.1
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	10.7	-3.3	-2.0	0.3	-0.1	-0.7	-2.0	-1.8	1.8
Glaucoma (self-reported)	0.8	0.9	2.5	1.4	-0.4	-1.6	1.5	-0.1	0.7	-0.0	-0.1
Gout (self-reported)	0.6	0.9	3.9	0.7	-0.6	-2.0	-0.2	-0.5	-0.3	-0.2	1.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.0	0.7	1.0	0.5	0.3	-0.1	0.8	0.9	0.5
Medication: Amlodipine	0.6	0.9	4.2	1.1	-0.1	0.2	-0.2	1.0	2.0	0.7	-0.3
Medication: Ventolin 100micrograms inhaler	2.9	3.7	6.5	-1.3	-2.3	-2.0	-1.5	-1.3	-2.4	-2.6	1.2
Birth weight	2.1	4.5	11.9	-2.6	-1.1	-2.1	-2.2	-1.7	-3.5	0.8	1.8
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.6	1.9	0.8	-1.1	0.1	0.4	0.4	0.6	-1.9
High blood pressure (siblings)	0.3	0.5	2.0	0.9	1.4	0.4	-0.6	-0.0	0.5	0.5	-0.3
Forced vital capacity (FVC), Best measure	0.2	0.8	2.7	-1.5	-1.6	-0.1	-0.4	-0.9	-0.2	0.3	0.5
Body fat percentage	1.2	4.6	11.4	2.4	-0.8	2.0	3.4	1.5	3.0	0.6	-2.0
Leg fat percentage (right)	1.3	4.7	10.8	2.4	-0.2	2.8	3.3	1.6	2.5	1.5	-1.4
Arm fat-free mass (right)	1.6	8.3	15.0	3.7	-0.1	1.0	3.9	1.8	3.5	3.4	-3.1
Exposure to tobacco smoke outside home	1.3	1.7	3.0	1.7	-1.1	1.7	0.4	1.7	1.2	1.2	-0.9
Comparative body size at age 10	0.5	1.4	4.7	1.1	-0.5	0.4	1.5	0.2	2.2	1.5	0.3
Number of full brothers	0.8	1.0	4.2	0.9	0.5	2.1	0.7	-0.5	0.4	0.8	-1.2
Worry too long after embarrassment	0.4	0.6	3.1	-0.3	-0.6	-0.7	-0.1	0.4	-1.7	-0.7	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	1.0	-0.2	-0.8	1.1	0.2	-0.3	0.1	0.2
Wheeze or whistling in the chest in last year	0.9	1.7	3.9	2.0	0.1	-1.8	1.1	1.3	1.4	0.7	-0.9
Number of children fathered	0.7	0.8	4.1	-0.6	0.3	0.0	-0.5	-0.7	-1.0	-0.3	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	6.3	0.6	0.7	2.5	1.3	1.0	1.0	0.1	-0.6
Age at first live birth	0.5	0.9	2.0	-0.8	1.2	-1.4	-0.9	-0.4	-0.8	-0.8	1.1
Pulse wave peak to peak time	0.6	0.7	1.6	0.0	-0.9	-0.7	0.7	-0.9	-0.1	-1.0	1.2
Health satisfaction	0.4	0.5	1.8	0.6	0.3	0.1	-0.4	-0.5	0.4	0.9	-1.3
Shortness of breath walking on level ground	2.0	2.4	9.6	3.1	0.7	-0.5	0.9	1.2	1.7	1.4	-1.4
Qualifications: College or University degree	0.7	2.1	4.7	-0.8	1.7	-1.4	-2.2	-1.6	-1.4	-0.9	1.1
Eye problems/disorders: None of the above	0.8	1.0	3.5	-1.9	1.3	-0.1	-0.8	-0.3	-0.8	0.1	1.1
Mouth/teeth dental problems: Loose teeth	1.2	1.5	4.0	1.9	0.7	0.1	1.0	1.4	2.0	-0.4	-0.9
Emphysema/chronic bronchitis	1.7	1.9	4.0	1.5	-0.2	1.5	0.6	2.0	1.3	1.6	-1.5
Medication for pain relief, constipation, heartburn	0.4	0.7	2.5	-0.4	-1.6	0.3	0.3	1.1	-0.2	-1.1	-0.3
Neck or shoulder pain in last month	0.5	0.7	1.6	-1.0	-0.4	0.9	-0.9	0.7	-1.3	0.4	0.8
Medication: Blood pressure	3.0	5.2	22.3	4.7	1.3	-0.3	0.7	1.5	2.9	1.0	-2.4
Angina (self-reported)	2.9	3.8	13.5	2.1	2.5	1.7	-0.8	0.5	0.5	3.7	-1.5
Migraine (self-reported)	0.6	0.8	2.4	-0.9	-0.1	-0.9	0.1	-1.4	-0.2	-0.0	1.5
Medication: Ibuprofen	0.3	0.3	1.0	-0.5	1.0	0.3	-0.9	-0.4	-0.3	-0.3	-0.3
Medication: Allopurinol	1.1	1.4	2.8	-0.3	0.3	-1.6	-0.8	-1.2	-1.3	-1.5	1.7
Medication: Omeprazole	0.9	1.1	2.3	1.1	0.4	-1.0	0.1	1.5	1.1	1.5	-0.9
Medication: Seretide 50 evohaler	1.0	1.1	2.6	1.6	0.3	0.1	1.5	-1.1	0.9	-0.4	1.3
Mean time to correctly identify matches	1.0	1.8	6.3	-1.9	0.0	0.1	-2.5	-0.4	-1.1	1.4	1.2
Heart disease (mother)	0.3	0.4	1.7	0.2	-0.2	-1.3	-0.5	-0.3	0.1	-0.7	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.3	1.1	1.4	1.1	-0.0	1.5	1.4	0.8	-0.4
Whole body fat mass	1.8	7.5	17.3	3.3	-0.5	2.0	4.2	1.8	3.9	1.7	-2.5
Leg fat mass (right)	2.1	8.3	17.0	3.5	-0.1	2.4	4.1	2.1	3.7	2.6	-2.5
Arm predicted mass (right)	1.4	7.0	13.8	3.1	-0.2	1.1	3.7	1.5	3.0	3.4	-3.0
Pulse rate, automated reading	1.3	4.3	8.9	2.4	0.8	2.2	-0.1	2.5	3.0	2.4	-1.5
Alcohol intake frequency.	0.7	1.7	6.2	-1.6	-1.1	-1.2	-0.5	-2.5	-1.5	-0.1	0.5
Comparative height size at age 10	0.3	1.8	6.6	-1.1	-0.9	-2.6	-1.3	-0.8	0.1	-0.5	1.8
Number of full sisters	2.1	2.5	5.3	1.2	-0.9	0.9	1.8	2.3	1.0	1.6	-2.2
Suffer from ‘nerves’	1.4	2.1	7.1	-0.9	-2.7	0.1	-1.1	0.3	-2.3	-1.5	0.8
Overall health rating	1.1	2.4	5.4	2.2	-0.3	-1.0	1.1	1.6	2.0	2.3	-0.5
Chest pain or discomfort	0.8	1.1	4.2	0.3	0.7	-2.1	-0.7	0.1	1.0	1.5	0.4
Had major operations	0.6	0.7	1.5	-0.9	0.3	0.9	-0.8	-1.2	-0.8	0.8	-0.8
Age at last live birth	0.3	0.4	0.9	0.5	-0.3	-1.0	-0.0	0.6	0.9	0.4	-0.7
Family relationship satisfaction	1.1	1.4	3.0	-1.5	-1.7	-0.5	-1.4	-1.0	-1.2	1.1	-0.1
Leg pain on walking	1.2	1.5	5.6	1.4	-0.4	1.4	-0.1	0.7	0.7	2.4	-1.4
Qualifications: NVQ or HND or HNC or equivalent	2.0	2.4	7.0	2.6	-0.6	1.1	1.7	0.5	1.3	1.6	-1.9
Commuting to job workplace: Car/motor vehicle	3.1	3.6	9.5	2.2	-1.7	0.4	3.1	1.6	2.1	0.6	-2.0
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.9	0.6	1.4	-1.7	0.7	-0.9	-0.5	-1.2	1.4
Medication: Aspirin	0.9	1.2	3.7	1.9	1.7	-0.4	0.7	-0.5	1.1	0.7	0.5
Supplements: Vitamin C	1.9	2.3	4.3	-1.5	0.6	-1.4	-1.7	-2.0	-1.5	-0.1	2.1
Knee pain experienced in last month	0.7	1.2	3.1	-0.2	1.3	0.9	-1.2	0.6	0.0	1.3	-1.8
Hypertension (Self-reported)	3.4	9.5	33.0	5.7	0.9	1.1	1.1	2.6	5.0	1.9	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	4.0	-2.0	1.1	-0.6	0.2	-0.1	-0.4	1.2	1.1
Illnesses of father: Heart disease	0.4	0.6	1.5	1.2	0.3	0.4	-0.4	0.7	0.5	-1.2	-0.6
Illnesses of siblings: Diabetes	0.8	1.0	2.5	1.6	1.2	-1.3	1.2	0.7	-0.4	-0.2	0.0
Smoking status: Previous	1.4	2.1	7.1	2.7	-0.3	0.8	0.9	2.1	1.8	0.9	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.6	9.1	0.5	-2.5	0.4	0.3	0.8	1.6	1.3	-3.0
Whole body fat-free mass	1.0	5.9	12.7	2.9	0.2	0.7	3.6	1.4	3.2	2.9	-2.4
Leg fat-free mass (right)	1.6	8.4	17.8	3.7	-0.2	0.6	4.1	2.3	4.2	2.3	-2.8
Arm fat percentage (left)	1.6	6.6	14.6	3.1	-0.0	2.0	3.8	2.0	3.8	1.2	-2.1
Average weekly red wine intake	4.0	5.8	13.3	3.4	3.6	-0.9	1.5	3.1	2.7	0.0	-1.2
Handedness (chirality/laterality): Left-handed	3.4	4.1	8.6	-2.9	-1.6	-2.2	-1.3	-2.1	-1.9	-1.9	2.0
Mood swings	0.4	0.7	3.1	0.6	-1.0	-0.3	1.8	-0.2	-0.0	-0.2	1.2
Loneliness, isolation	0.5	0.6	2.5	-0.8	-0.8	-0.2	-0.2	-0.7	-1.6	-0.6	-0.6
Long-standing illness, disability or infirmity	0.1	0.2	0.6	0.6	0.4	0.1	0.7	-0.1	-0.1	0.4	-0.8
Ever had bowel cancer screening	5.2	6.0	20.9	-3.0	0.1	-1.8	-2.3	-2.2	-2.0	0.9	4.6
Diabetes diagnosed by doctor	2.6	4.3	10.6	3.3	0.6	1.4	1.8	1.0	2.3	2.6	-2.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.2	-0.2	0.8	-1.1	-0.6	-0.6	-0.5	-0.9	0.6
Friendships satisfaction	0.2	0.3	0.8	0.4	0.6	-0.1	-0.8	-0.4	-0.4	0.4	-0.9
Qualifications: nursing, teaching	0.5	0.8	2.3	-1.5	-0.3	-0.9	-0.8	-0.9	-0.7	0.5	1.0
Commuting to job workplace: Walk	0.3	0.4	1.7	-0.6	-1.3	0.0	0.0	-0.0	0.4	-0.2	-0.8
Eye problems/disorders: Cataract	0.5	0.6	1.9	0.2	-0.3	-0.3	-0.8	-1.4	-0.3	-0.5	1.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.1	0.3	-0.2	-0.8	0.6	-0.2	-1.1	-0.6	0.4
Medication for cholesterol	3.8	5.7	16.0	-4.0	-1.4	-2.4	-1.7	-1.9	-3.1	-2.0	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.2	0.2	-1.1	-0.4	-1.0	-1.5	-0.4	-0.3	0.5
Back pain experienced in last month	0.3	0.5	1.2	-0.7	0.8	0.2	-0.6	0.7	-0.7	1.1	0.1
Mineral and other dietary supplements	1.4	1.8	3.8	1.5	-0.1	1.2	1.0	1.5	1.9	0.6	-1.9
Breast cancer (self-reported)	1.9	2.3	5.4	-2.3	-2.3	0.1	-1.7	-0.3	-1.9	-0.2	0.7
Asthma (self-reported)	1.5	2.9	6.1	-1.6	-1.3	-1.9	-1.0	-2.0	-2.5	-1.3	1.7
Osteoporosis (self-reported)	0.7	0.9	2.7	-0.7	-0.3	-0.4	-1.1	1.6	0.3	1.5	0.5
Osteoarthritis (self-reported)	0.4	0.5	1.1	0.4	-0.9	-1.0	1.0	-0.1	0.1	0.4	-1.1
Medication: Aspirin	0.9	1.2	4.5	2.1	1.4	-0.4	0.5	-0.3	1.3	0.7	-0.0
Medication: Gliclazide	0.5	0.6	1.5	1.0	1.1	0.2	1.2	-0.7	0.3	-0.3	0.5
Illnesses of father: None of the above (group 1)	0.6	0.8	3.4	-1.8	-0.3	-0.7	-0.9	-0.7	-0.4	-0.8	0.1
Smoking status: Current	1.3	2.1	8.5	0.9	2.9	0.8	-1.2	1.2	0.3	1.1	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.4	-2.1	-0.3	0.3	-1.4	-1.7	-0.8	0.9	0.9
Whole body water mass	1.1	6.4	13.3	3.0	0.1	0.7	3.6	1.6	3.3	2.9	-2.4
Leg predicted mass (right)	1.6	8.4	17.9	3.7	-0.2	0.6	4.1	2.2	4.2	2.2	-2.8
Arm fat mass (left)	2.2	9.1	19.4	3.7	-0.1	2.1	4.4	2.4	4.3	2.3	-2.6
Number of self-reported non-cancer illnesses	0.6	1.1	2.7	0.7	0.8	-1.6	-1.3	-0.8	0.5	1.2	0.8
Average weekly champagne plus white wine intake	1.3	1.8	4.4	-0.8	-0.4	2.1	-0.4	-1.4	-1.4	-1.5	1.7
Miserableness	0.7	1.1	3.5	1.5	-0.5	1.3	1.9	1.2	0.5	0.1	0.1
Guilty feelings	1.0	1.5	4.8	-0.1	-0.1	-2.2	1.4	-0.4	0.3	0.1	2.2
Wears glasses or contact lenses	0.6	0.7	2.0	-0.6	0.5	0.7	-0.7	-0.5	-1.4	0.3	1.3
Ever taken oral contraceptive pill	1.1	1.2	2.4	-0.2	1.0	-1.5	-0.9	-1.4	-0.2	-1.6	-1.2
Hearing aid user	0.8	0.9	1.8	1.3	-0.5	-0.9	1.3	0.6	0.6	0.4	-1.2
Mother’s age at death	0.8	1.0	2.4	-0.9	-0.8	-0.4	-1.1	-1.5	-1.4	-0.6	0.2
Financial situation satisfaction	0.4	0.4	1.1	-0.6	-1.1	-0.9	0.2	-0.8	-0.2	0.2	-0.6
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.2	0.7	-1.0	0.1	-0.1	0.4	0.1	1.1	-0.9
Commuting to job workplace: Public transport	1.3	1.6	6.2	-1.0	2.5	-0.3	-1.4	-0.6	-1.2	-1.2	0.8
Eye problems/disorders: Glaucoma	0.9	1.1	2.2	1.4	-1.3	-1.5	1.5	-0.4	0.3	0.2	-0.5
Medication: Blood pressure	2.5	4.7	14.2	3.8	1.7	2.1	0.5	0.9	3.6	1.5	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.6	-0.3	0.8	-0.1	-1.2	-1.2	-0.3	1.0	-0.3
Supplements: Fish oil (including cod liver oil)	2.3	3.1	6.3	-1.9	-1.0	-1.9	-0.9	-1.7	-2.0	-1.5	2.5
High cholesterol (Self-reported)	2.5	4.4	13.3	2.5	1.4	1.0	0.7	0.6	3.6	3.4	0.3
Medication: Bendroflumethiazide	1.0	1.6	6.4	2.5	0.5	1.0	-0.0	0.4	1.7	-1.3	-0.5
Medication: Paracetamol	0.6	0.9	3.4	1.1	0.4	0.9	0.3	0.5	1.1	1.8	-0.3
Medication: Lisinopril	0.6	0.8	1.7	1.0	0.3	0.9	-1.3	1.3	0.4	0.8	0.6
Medication: Atorvastatin	2.2	2.7	7.5	2.0	2.7	0.8	-1.1	-0.1	1.0	2.6	-0.7
Illnesses of father: High blood pressure	2.5	3.1	6.3	2.5	1.4	0.1	1.6	2.1	2.3	2.0	-0.3
Alcohol drinker status: Never	0.6	0.7	1.7	-0.6	0.7	-1.0	-0.7	-1.3	-1.2	-0.3	-0.3
Ever smoked	0.7	1.2	3.9	2.0	0.9	1.3	-0.5	1.6	0.5	0.6	-0.1
Basal metabolic rate	1.3	7.2	15.4	3.3	-0.1	1.0	3.9	1.7	3.6	2.8	-2.6
Leg fat percentage (left)	1.4	5.0	11.1	2.5	-0.3	2.7	3.3	2.0	2.7	1.5	-1.6
Arm fat-free mass (left)	1.2	6.3	13.6	2.7	-0.4	1.3	3.3	1.7	2.9	3.7	-2.4
Number of operations (self-reported)	0.8	1.2	4.1	-2.0	-0.0	-0.1	-0.7	-1.2	-0.8	1.5	0.9
Average weekly beer plus cider intake	0.2	0.2	1.0	0.0	0.6	-0.6	-0.2	-0.4	-0.2	-1.0	-0.2
Irritability	0.5	0.8	4.1	0.7	-0.1	-0.8	2.0	-0.6	-0.1	0.6	0.6
Risk taking	0.3	0.4	1.8	0.7	0.1	-1.4	-0.5	-0.6	0.4	0.0	-0.0
Ever had prostate specific antigen (PSA) test	2.6	2.9	7.2	-2.0	0.1	0.7	-2.7	-2.4	-1.8	0.9	1.5
Fractured/broken bones in last 5 years	0.6	0.8	2.6	0.4	-1.6	-1.3	-0.3	-0.6	1.0	0.8	-0.2
Age started oral contraceptive pill	0.5	0.7	1.4	-0.6	0.2	0.9	-1.2	0.8	0.1	1.1	-0.9
Diastolic blood pressure, automated reading	2.5	7.7	17.3	4.2	2.9	1.8	1.1	3.2	3.6	1.8	-2.2
Ever depressed for a whole week	0.7	0.8	2.7	-0.4	1.2	-0.4	-0.9	-1.7	-0.7	-0.8	0.5
Unable to work because of sickness or disability	1.0	1.3	4.8	1.5	0.0	-0.8	-1.0	0.3	-0.3	1.1	-2.2
Commuting to job workplace: Cycle	2.4	3.0	10.4	-2.5	-1.0	-0.7	-1.2	-1.0	-3.2	-0.9	1.5
Myopia	0.5	0.7	1.9	-1.4	-1.2	0.3	-0.3	-0.7	-0.2	-0.6	1.0
Vascular/heart problems diagnosed by doctor	3.8	10.3	34.6	-5.9	-1.8	-1.2	-0.8	-3.0	-4.6	-2.6	2.3
Cholesterol lowering medication	3.9	5.7	11.8	3.3	2.4	1.8	1.5	1.0	3.3	3.4	0.8
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	5.1	1.1	1.0	-0.7	-0.9	2.2	1.2	2.2	-1.2
Pain experienced in last month	0.7	1.2	3.6	1.6	0.2	0.4	1.1	-0.3	1.2	-1.9	0.8
Supplements: Calcium	4.5	4.9	11.7	-3.0	0.9	-1.9	-2.8	-2.0	-3.4	-0.7	1.5
Basal cell carcinoma (self-reported)	2.3	2.8	10.5	0.1	3.2	0.9	-0.4	-0.6	-1.5	1.6	-2.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.4	1.0	0.4	-1.1	-0.4	0.6	-0.2	1.2	0.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.3	-0.9	-0.9	-1.1	-0.8	-0.2	0.1	-0.6	0.7
Heart disease (siblings)	1.1	1.4	4.1	-0.2	2.0	-0.4	-1.1	0.1	-1.1	-0.6	1.9
Alcohol drinker status: Previous	1.2	1.4	3.6	-1.5	-1.1	-0.6	-1.9	-0.7	-1.5	0.7	0.5
Pack years of smoking	1.4	2.1	4.3	1.6	1.2	-1.2	1.0	1.5	1.5	2.1	-0.9
Impedance of whole body	2.6	13.3	21.9	-4.5	-1.1	-2.4	-4.2	-3.9	-4.2	-4.7	2.5
Leg fat mass (left)	2.1	8.1	16.8	3.6	-0.0	2.3	4.1	2.1	3.7	2.4	-2.5
Arm predicted mass (left)	1.3	6.8	13.0	3.0	-0.1	1.3	3.6	1.7	2.9	3.5	-2.6