TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Lung FEV1/FVC ratio
:
←
→
chr8:8,295,058-9,692,925
Best TWAS P=3.5e-11 · Best GWAS P=1.16e-14 conditioned to 5.67e-06
8.4M
8.6M
8.8M
9M
9.2M
9.4M
9.6M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
PPP1R3B
0.06
0.01
blup
69
0.02
2.6e-03
-0.5
6.6
3.5e-11
-0.64
0.02
0.54
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
PPP1R3B
0.03
0.03
enet
8
0.03
1.8e-06
-7.3
5.6
2.1e-08
-0.78
0.04
0.96
FALSE
1
NTR
Blood
PPP1R3B
0.03
0.02
enet
11
0.02
1.5e-07
-6.2
-5.6
2.3e-08
0.60
0.98
0.02
FALSE