Best TWAS P=3.5e-11 · Best GWAS P=1.16e-14 conditioned to 5.67e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | PPP1R3B | 0.03 | 0.02 | enet | 11 | 0.02 | 1.5e-07 | -6.2 | -5.6 | 2.3e-08 | 0.60 | 0.98 | 0.02 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PPP1R3B | 0.03 | 0.03 | enet | 8 | 0.03 | 1.8e-06 | -7.3 | 5.6 | 2.1e-08 | -0.78 | 0.04 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PPP1R3B | 0.06 | 0.01 | blup | 69 | 0.02 | 2.6e-03 | -0.5 | 6.6 | 3.5e-11 | -0.64 | 0.02 | 0.54 | TRUE |