Best TWAS P=2.95e-08 · Best GWAS P=1.61e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | LACTB2 | 0.05 | 0.03 | lasso | 6 | 0.02 | 1.4e-02 | -5.5 | -5.1 | 3.0e-07 | 0.89 | 0.05 | 0.91 | FALSE |
| 2 | GTEx | Stomach | LACTB2 | 0.10 | 0.08 | enet | 21 | 0.04 | 3.4e-03 | -5.6 | -5.2 | 2.5e-07 | 0.96 | 0.04 | 0.96 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | LACTB2 | 0.05 | 0.07 | lasso | 3 | 0.08 | 6.3e-10 | -5.6 | -5.5 | 2.9e-08 | 0.96 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LACTB2 | 0.03 | 0.03 | lasso | 1 | 0.03 | 1.7e-04 | -5.2 | -5.2 | 1.9e-07 | 0.99 | 0.01 | 0.89 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LACTB2 | 0.03 | 0.02 | lasso | 3 | 0.02 | 6.1e-03 | -5.5 | -5.3 | 1.1e-07 | 0.99 | 0.01 | 0.92 | FALSE |