TWAS hub - LACTB2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0700	0.0260	3.7e-08	0.090	0.078	0.079	0.078	0.082	4.7e-11	1.0e-09	6.4e-10	8.4e-10	3.7e-10
2	GTEx	Artery Tibial	0.1734	0.0552	6.7e-07	0.022	NA	0.064	NA	0.034	6.6e-03	NA	1.0e-05	NA	1.0e-03
3	GTEx	Cells Transformed fibroblasts	0.0510	0.0240	2.7e-03	0.004	NA	0.018	NA	0.018	1.6e-01	NA	1.6e-02	NA	1.6e-02
4	GTEx	Heart Atrial Appendage	0.1940	0.0750	1.9e-06	0.127	NA	0.157	NA	0.028	2.6e-06	NA	1.6e-07	NA	2.0e-02
5	GTEx	Heart Left Ventricle	0.0701	0.0342	1.2e-03	0.012	NA	0.007	NA	0.021	7.2e-02	NA	1.2e-01	NA	2.5e-02
6	GTEx	Lung	0.0469	0.0240	2.4e-03	0.026	NA	0.013	NA	0.018	3.9e-03	NA	3.5e-02	NA	1.4e-02
7	GTEx	Muscle Skeletal	0.0863	0.0283	7.5e-09	0.066	NA	0.091	NA	0.086	4.5e-07	NA	2.9e-09	NA	9.2e-09
8	GTEx	Nerve Tibial	0.0699	0.0323	2.0e-04	0.058	NA	0.035	NA	0.035	6.3e-05	NA	1.6e-03	NA	1.5e-03
9	GTEx	Pancreas	0.1350	0.0590	2.6e-04	0.109	NA	0.051	NA	0.013	2.5e-05	NA	3.3e-03	NA	9.3e-02
10	GTEx	Pituitary	0.2470	0.0800	1.2e-04	0.081	NA	0.127	NA	0.128	4.7e-03	NA	4.6e-04	NA	4.3e-04
11	GTEx	Skin Not Sun Exposed Suprapubic	0.0720	0.0310	3.9e-04	0.069	NA	0.058	NA	0.073	1.2e-04	NA	3.9e-04	NA	7.5e-05
12	GTEx	Skin Sun Exposed Lower leg	0.0470	0.0220	3.8e-04	0.030	NA	0.017	NA	0.037	1.4e-03	NA	1.4e-02	NA	4.6e-04
13	GTEx	Stomach	0.0990	0.0400	4.3e-05	0.079	NA	0.045	NA	0.042	1.3e-04	NA	3.4e-03	NA	4.5e-03
14	GTEx	Testis	0.0960	0.0430	2.1e-03	0.063	NA	0.076	NA	0.063	9.2e-04	NA	2.9e-04	NA	9.0e-04
15	GTEx	Whole Blood	0.0590	0.0300	2.4e-03	0.003	NA	0.023	NA	0.006	1.5e-01	NA	3.1e-03	NA	8.9e-02
16	NTR	Blood	0.0174	0.0080	1.5e-04	0.008	0.010	0.008	0.009	0.002	1.1e-03	2.0e-04	8.6e-04	4.5e-04	8.8e-02
17	ROSMAP	Brain Pre-frontal Cortex	0.0528	0.0180	1.5e-08	0.069	0.067	0.066	0.066	0.075	3.0e-09	5.8e-09	6.7e-09	6.5e-09	6.4e-10
18	YFS	Blood	0.1820	0.0327	0.0e+00	0.186	0.190	0.191	0.197	0.197	1.0e-58	5.8e-60	3.1e-60	2.6e-62	1.7e-62
19	TCGA	Bladder Urothelial Carcinoma	0.0340	0.0210	7.9e-03	0.020	0.015	0.015	NA	0.006	7.9e-03	1.6e-02	1.9e-02	NA	1.0e-01
20	TCGA	Head and Neck Squamous Cell Carcinoma	0.0337	0.0279	6.8e-03	0.034	0.020	0.030	NA	0.031	1.0e-04	2.0e-03	2.3e-04	NA	1.7e-04
21	TCGA	Brain Lower Grade Glioma	0.0284	0.0177	3.1e-03	0.015	0.010	0.017	NA	0.016	7.7e-03	2.5e-02	4.1e-03	NA	5.0e-03
22	TCGA	Pheochromocytoma and Paraganglioma	0.1170	0.0610	1.7e-04	0.088	0.062	0.102	NA	0.111	2.4e-04	1.8e-03	7.8e-05	NA	3.7e-05
23	TCGA	Prostate Adenocarcinoma	0.0296	0.0197	4.3e-03	0.022	0.009	0.011	NA	0.017	2.3e-03	3.4e-02	2.3e-02	NA	6.1e-03
24	TCGA	Thyroid Carcinoma	0.0260	0.0180	8.1e-03	0.006	0.006	0.007	NA	0.001	8.5e-02	7.1e-02	6.1e-02	NA	2.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Heel T-Score	21.6	172.1	243.4	-15.3	-5.7	-14.1	-14.7	-14.8	-15.4	-14.3	-14.7	-15.0	-10.7	-15.1	-15.6	-15.1	-9.6	-8.1	-11.4	-15.5	-0.4	-8.2	-14.4	-9.9	-14.9	-15.0	-13.6
Heel bone mineral density (BMD) T-score, automated (left)	9.8	22.2	34.5	-5.9	-3.4	-5.0	-5.6	-5.0	-5.0	-4.6	-5.5	-5.7	-5.4	-5.8	-5.4	-4.9	-4.5	-2.5	-3.2	-4.8	-0.3	-2.3	-4.0	-4.7	-4.7	-4.5	-5.8
Heel bone mineral density (BMD) T-score, automated (right)	6.8	15.5	24.9	-4.5	-3.0	-4.3	-4.7	-4.1	-4.2	-3.9	-4.9	-4.9	-3.9	-4.5	-4.4	-4.1	-3.3	-2.2	-3.0	-4.1	0.2	-1.8	-3.5	-4.0	-4.1	-3.9	-5.0
Medication for cholesterol, blood pressure or diabetes	4.2	6.9	15.8	3.8	3.1	3.1	2.5	3.0	2.9	2.4	2.8	3.0	3.8	4.0	3.3	2.3	1.8	0.6	1.1	2.5	1.3	-0.0	1.6	1.8	2.2	2.0	3.6
Waist Hip Ratio (WHR)	4.0	18.1	44.3	-5.8	-5.4	-5.7	-3.3	-5.0	-4.4	-3.8	-5.2	-5.6	-4.7	-6.1	-5.3	-3.7	-1.6	0.6	-2.1	-3.6	-0.8	1.1	-2.1	-3.9	-3.9	-3.0	-6.7
Verbal and Numeric Reasoning (VNR)	3.8	9.2	25.0	-2.9	-2.9	-3.7	-4.5	-3.3	-2.4	-3.0	-3.9	-3.9	-5.0	-3.0	-2.4	-2.8	-2.1	0.7	-2.9	-2.2	1.2	0.2	-1.6	-3.4	-2.9	-2.0	-4.6
Fed-up feelings	3.8	6.8	14.4	1.4	1.0	3.3	3.0	2.5	3.0	2.9	3.2	3.1	1.1	1.3	2.1	3.2	0.9	0.8	3.7	2.9	-2.7	1.9	3.2	2.1	3.8	3.4	2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.7	12.1	0.9	-1.6	2.4	3.0	2.5	2.6	2.8	2.4	2.2	2.1	0.9	1.1	2.8	0.1	0.3	3.5	2.6	-1.7	1.4	2.6	0.7	2.9	2.7	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.5	4.1	7.7	-2.7	-1.1	-2.8	-2.7	-2.5	-2.5	-2.4	-2.3	-2.2	-2.3	-2.6	-2.4	-2.0	-0.5	-1.1	-1.4	-2.1	-0.8	0.0	-1.5	-1.1	-2.1	-1.9	-2.4
Alzheimer’s Disease (in mother)	3.4	4.0	7.5	2.4	-0.9	2.2	2.1	2.7	2.6	2.3	1.7	1.5	1.5	2.4	2.6	2.2	0.6	1.7	1.6	2.5	1.5	1.1	2.6	0.0	2.3	2.5	1.5
Major Depression (MDD)	3.3	4.1	10.8	1.6	0.6	2.3	3.3	2.7	2.4	2.5	2.4	2.5	2.0	1.8	1.6	2.4	0.6	0.2	2.2	2.3	-1.2	0.8	1.8	1.6	2.2	2.2	1.9
Bipolar Disorder (2011)	3.3	3.2	6.1	1.4	0.1	1.5	1.7	1.9	2.1	2.1	1.8	1.8	1.0	1.4	1.9	2.3	1.7	1.9	1.9	2.4	-0.4	2.1	2.5	1.1	2.2	2.4	1.0
Lung FEV1/FVC ratio	3.3	16.8	30.7	-4.2	0.1	-3.5	-4.6	-4.5	-5.1	-4.8	-4.0	-4.4	-1.2	-4.0	-4.7	-5.2	-3.2	-2.4	-4.7	-5.5	0.6	-4.3	-5.2	-2.8	-4.7	-5.3	-2.8
Commuting to job workplace: Public transport	3.3	3.9	8.3	-2.0	1.1	-2.0	-2.9	-2.6	-2.4	-2.5	-1.7	-1.6	-2.3	-2.0	-1.9	-2.2	-1.2	-2.6	-1.5	-2.4	-1.1	-1.3	-2.3	-0.1	-2.1	-2.2	-0.9
Eye problems/disorders: Diabetes related eye disease	3.2	3.5	6.1	-2.5	-1.0	-2.0	-1.7	-2.4	-2.4	-2.2	-1.7	-1.9	-1.5	-2.3	-2.2	-2.2	-1.3	-1.0	-2.0	-2.4	-0.9	-0.7	-1.9	-0.9	-1.8	-2.0	-2.1
Medication: Gliclazide	3.2	3.6	8.4	-2.4	-1.9	-2.1	-1.4	-2.9	-2.5	-1.9	-1.8	-2.2	-2.2	-2.7	-2.4	-1.9	-1.1	-0.8	-1.4	-2.2	-0.9	-0.5	-1.6	-0.8	-1.7	-1.8	-2.0
Wears glasses or contact lenses	3.2	3.7	7.4	1.3	0.1	1.8	1.9	1.7	2.0	1.8	2.1	2.4	0.7	1.3	1.6	2.5	1.6	1.6	2.7	2.2	-1.7	2.1	2.3	2.1	2.3	2.4	1.5
Hair/balding pattern: Pattern 4	3.1	7.6	13.5	-2.9	-0.0	-3.2	-3.7	-2.8	-3.3	-3.0	-3.0	-3.0	-2.0	-2.8	-3.0	-3.3	-1.2	-2.2	-2.7	-3.4	0.3	-2.0	-3.2	-1.9	-3.3	-3.5	-2.5
Breast Cancer	3.0	7.3	12.4	3.1	3.0	2.9	2.8	2.7	2.7	2.8	3.5	3.5	2.2	3.0	3.2	2.8	1.9	1.6	1.9	2.6	-1.0	1.2	2.3	3.2	2.8	2.6	3.5
Commuting to job workplace: Car/motor vehicle	3.0	3.4	7.2	1.6	-1.8	0.9	2.6	1.5	1.5	2.3	2.0	1.8	0.8	1.5	1.6	2.0	2.4	2.7	1.5	1.9	-0.5	2.6	2.1	1.9	1.8	2.0	0.6
Ever had hysterectomy (womb removed)	2.8	3.1	6.1	1.9	0.9	1.8	0.8	1.9	2.4	2.2	1.9	1.8	0.6	1.8	2.3	2.3	0.6	-0.1	1.9	2.5	-0.3	0.8	2.5	0.6	2.2	2.3	2.0
Fluid intelligence score	2.8	5.8	17.8	-2.1	-2.2	-2.6	-3.6	-2.6	-1.9	-2.3	-3.0	-3.0	-4.2	-2.2	-2.1	-2.3	-2.1	-0.9	-2.2	-1.8	0.9	-0.3	-1.3	-2.8	-2.1	-1.6	-3.5
Medication: Cholesterol lowering	2.8	4.4	11.1	-3.1	-2.6	-2.2	-1.7	-2.4	-2.1	-2.0	-2.1	-2.3	-3.3	-3.3	-2.7	-1.7	-1.7	-1.3	-0.4	-1.8	-1.4	-0.1	-1.0	-1.7	-1.5	-1.4	-2.8
Medication: Metformin	2.7	3.8	8.8	-2.7	-2.0	-2.1	-1.6	-2.4	-2.2	-2.1	-2.0	-2.2	-3.0	-3.0	-2.6	-1.6	-1.3	-1.5	-0.5	-1.9	-1.6	0.0	-1.1	-1.1	-1.3	-1.4	-2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.8	10.2	-2.5	-1.1	-2.5	-3.2	-1.9	-2.4	-2.1	-3.0	-3.1	-2.3	-2.4	-2.3	-2.8	-1.9	-1.0	-2.6	-2.4	1.2	-1.6	-2.3	-3.0	-2.9	-2.6	-2.7
Schizophrenia vs Biploar Disorder	2.6	3.5	9.1	-1.0	0.3	-0.9	-1.6	-1.5	-2.0	-2.1	-1.7	-1.8	-0.6	-0.9	-1.7	-2.6	-1.1	-1.3	-3.0	-2.6	1.8	-2.6	-2.9	-1.2	-2.2	-2.6	-0.5
Medication: Ibuprofen (e.g. Nurofen)	2.6	3.2	6.3	1.5	0.3	2.0	2.3	2.5	2.0	2.3	2.2	2.4	0.1	1.6	1.6	2.0	1.1	0.7	1.8	1.9	-1.2	1.7	1.9	1.8	2.2	2.1	1.3
Type 2 Diabetes (T2D) (2018)	2.4	4.5	9.0	-2.4	-1.7	-2.2	-2.5	-2.0	-2.2	-2.1	-2.5	-2.5	-3.0	-2.7	-2.5	-2.0	-1.9	-2.4	-0.9	-2.0	-0.6	-0.7	-1.6	-2.0	-1.8	-1.7	-2.6
Hypothyroidism/myxoedema (self-reported)	2.4	4.6	8.2	-2.0	-0.9	-2.8	-2.7	-2.4	-2.3	-2.4	-2.9	-2.8	-1.2	-1.9	-1.9	-2.5	-0.7	-0.0	-2.8	-2.2	1.2	-1.0	-2.1	-2.1	-2.8	-2.3	-2.2
Medication: Blood pressure	2.4	4.6	9.8	1.9	0.7	3.1	2.6	2.5	2.9	2.8	2.1	1.7	1.8	1.9	2.2	2.3	0.5	1.8	1.7	2.7	0.6	0.1	2.6	0.1	2.8	2.6	2.6
Intelligence (Savage-Jansen 2018)	2.3	6.9	22.8	-2.8	-2.7	-3.4	-4.0	-2.8	-2.1	-1.9	-3.3	-3.3	-4.8	-2.9	-2.4	-2.1	-1.6	0.2	-2.1	-1.6	0.4	0.7	-1.1	-2.8	-2.3	-1.4	-4.2
Type 2 Diabetes (T2D) (2012)	2.3	2.6	6.9	-2.6	-1.0	-0.9	-1.7	-2.6	-1.2	-2.3	-1.7	-1.7	-0.9	-2.5	-2.0	-1.2	-2.2	-0.5	-0.2	-0.8	-1.0	-1.1	-1.2	-2.1	-1.0	-1.1	-1.8
Length of working week for main job	2.3	2.5	8.1	1.9	0.1	1.9	2.2	2.9	2.1	1.5	1.4	1.3	2.1	1.8	1.4	1.7	0.4	0.6	1.4	1.9	0.9	0.5	1.8	-0.1	1.7	1.7	1.1
Chronic bronchitis/emphysema (father)	2.2	2.6	6.4	1.1	-0.9	0.7	1.9	1.0	1.6	1.2	1.5	1.7	-0.2	1.0	1.3	2.0	1.6	2.2	2.0	2.1	-1.3	2.5	2.3	1.4	1.7	2.2	0.8
Townsend deprivation index at recruitment	2.0	2.8	5.7	1.8	-0.1	2.1	2.1	2.2	2.4	2.1	1.4	1.3	1.1	1.7	1.9	1.8	0.8	1.4	1.4	2.1	0.4	0.8	2.0	0.2	2.1	2.1	1.4
Taking other prescription medications	2.0	3.0	6.1	-1.9	-0.9	-2.1	-2.5	-1.7	-1.8	-1.6	-2.1	-2.4	-1.2	-1.9	-1.9	-1.9	-0.9	-0.6	-1.8	-1.8	0.5	-0.6	-1.4	-2.0	-1.8	-1.8	-2.2
Osteoarthritis (self-reported)	2.0	2.6	8.2	0.6	0.2	1.8	1.5	1.0	1.8	1.2	1.6	1.9	0.5	0.5	1.0	2.2	0.0	0.0	2.9	2.0	-2.4	1.1	2.2	1.1	2.4	2.2	1.6
Multivitamins +/- minerals	1.9	2.5	6.7	2.6	0.7	1.6	1.1	1.9	1.9	1.7	1.5	1.7	1.0	2.5	2.2	1.5	1.4	1.0	0.5	1.8	1.4	0.5	1.2	1.0	1.2	1.4	2.1
Medication: Levothyroxine sodium	1.9	3.3	5.9	-1.8	-0.8	-2.4	-2.1	-2.2	-2.2	-2.3	-2.3	-2.2	-0.9	-1.7	-1.9	-2.1	-0.1	0.0	-2.3	-2.1	0.2	-0.5	-1.9	-1.2	-2.2	-2.0	-1.8
Financial difficulties in last 2 years	1.9	2.6	4.8	1.3	0.4	1.7	1.8	1.9	2.0	1.9	1.6	1.6	1.1	1.3	1.8	1.9	0.0	1.5	2.0	2.0	-0.8	1.0	2.2	0.7	2.0	2.2	1.4
Diabetes diagnosed by doctor	1.9	3.2	6.8	-2.2	-2.3	-2.0	-1.6	-2.2	-2.1	-1.9	-1.9	-2.1	-2.6	-2.5	-2.3	-1.6	-1.2	-1.1	-0.8	-1.8	-0.9	0.2	-1.0	-1.0	-1.3	-1.3	-2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	4.1	-1.3	-0.5	-1.6	-1.6	-1.5	-1.5	-1.5	-2.0	-1.9	-0.7	-1.4	-1.6	-1.6	-1.1	-0.1	-1.6	-1.4	0.8	-0.8	-1.4	-1.7	-1.8	-1.6	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	4.7	1.0	-0.3	1.1	2.2	1.6	1.1	1.5	1.7	1.7	1.3	1.0	1.3	1.7	1.6	1.3	2.1	1.3	-1.1	1.9	1.7	1.8	1.7	1.6	0.9
Medication: Ramipril	1.7	2.1	6.2	-2.5	-1.6	-1.1	-1.1	-1.7	-1.3	-1.4	-1.4	-1.6	-2.2	-2.4	-1.9	-1.1	-1.4	-0.8	-0.2	-1.2	-1.1	0.0	-0.5	-1.4	-0.6	-0.7	-2.2
Medication: Paracetamol	1.7	2.8	4.5	1.9	0.1	2.0	1.6	1.5	1.9	1.7	2.0	2.0	0.9	1.9	2.1	1.9	1.5	1.4	1.3	1.9	0.0	1.2	1.9	1.4	2.0	2.0	1.7
Heart disease (mother)	1.7	2.1	6.0	1.2	-1.7	0.3	2.1	1.1	1.4	1.4	1.2	1.4	-0.3	0.9	1.7	1.6	1.6	1.7	1.4	1.8	-0.5	2.5	1.9	1.1	1.4	1.8	-0.0
Hypothyroidism (self reported)	1.6	3.7	8.6	-1.0	-0.3	-2.3	-2.5	-1.7	-2.0	-2.2	-2.4	-2.4	0.1	-0.9	-1.4	-2.5	-0.2	0.3	-2.9	-2.1	2.2	-1.6	-2.3	-1.7	-2.7	-2.4	-1.3
Average weekly beer plus cider intake	1.6	2.3	6.9	1.2	-0.3	0.8	2.6	1.2	0.9	1.7	1.9	2.1	-0.0	1.1	1.4	1.6	1.8	-0.5	1.5	1.2	-2.1	1.9	1.1	2.5	1.4	1.3	1.0
Depressed Affect (Nagel 2018)	1.5	3.1	7.1	1.1	0.9	2.3	2.2	2.0	1.9	1.6	2.1	2.1	1.4	1.1	1.2	2.0	0.8	0.8	2.7	1.7	-1.8	1.2	1.9	1.3	2.4	2.1	1.5
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.0	-1.7	0.2	-1.6	-2.0	-1.5	-1.3	-1.6	-1.5	-1.3	-1.2	-1.6	-1.6	-1.4	-0.5	-0.9	-0.7	-1.3	-0.5	-0.7	-1.4	-0.7	-1.4	-1.3	-1.2
Illnesses of father: Heart disease	1.5	2.1	5.2	0.4	-0.8	1.2	0.9	1.8	1.7	1.7	1.5	1.8	-0.7	0.3	0.8	1.8	0.3	-1.0	2.3	1.8	-2.0	1.4	1.9	1.0	2.0	1.9	0.6
Mood swings	1.5	2.7	8.3	0.5	-0.5	2.0	2.1	1.6	1.9	1.6	1.6	1.6	1.0	0.5	1.1	2.0	0.2	-0.1	2.9	1.9	-1.9	1.1	2.2	0.7	2.5	2.3	1.1
Alcohol usually taken with meals	1.4	2.3	6.8	-0.0	2.4	-0.3	-2.1	-0.6	-0.8	-1.8	-1.5	-1.4	0.8	-0.1	-0.7	-1.7	-1.5	-0.5	-1.9	-1.4	2.6	-2.4	-1.7	-1.9	-1.4	-1.7	-0.3
Depression (self-reported)	1.4	1.7	5.1	0.7	-1.1	1.1	2.2	1.7	1.2	1.7	1.3	1.3	0.7	0.7	0.6	1.6	0.7	-0.2	2.0	1.4	-0.9	1.3	1.6	0.8	1.6	1.5	0.6
Pulse wave reflection index	1.4	1.7	4.6	-0.9	-0.7	-2.1	-2.2	-1.5	-1.8	-2.1	-1.4	-0.9	-0.6	-0.9	-1.3	-1.5	1.0	-0.2	-1.2	-1.5	0.1	0.3	-1.3	0.3	-1.7	-1.5	-1.2
Medication: Blood pressure	1.4	2.4	6.1	-2.2	-1.3	-1.6	-1.3	-1.9	-1.7	-1.4	-1.5	-1.9	-2.0	-2.5	-2.0	-1.5	-1.3	-1.0	-0.5	-1.7	-0.7	-0.5	-1.1	-1.1	-1.3	-1.4	-1.9
Suffer from ‘nerves’	1.4	2.1	6.2	0.6	0.0	2.0	1.8	1.3	1.5	1.4	1.6	1.5	1.4	0.6	0.5	1.8	-0.0	-1.5	2.5	1.5	-1.7	0.6	1.6	1.0	2.3	1.8	1.3
Leg pain on walking	1.4	1.8	13.9	-2.3	-1.8	-0.6	0.0	-1.1	-0.5	-0.8	-0.6	-0.3	-1.2	-2.4	-1.6	0.1	-1.2	-0.9	1.9	-0.2	-3.7	0.6	0.1	0.0	0.2	0.2	-1.0
Average weekly red wine intake	1.4	2.1	11.6	0.4	2.4	1.1	-1.4	-0.2	0.0	-1.5	-0.8	-0.7	1.1	0.5	-0.2	-1.2	-2.7	-1.8	-1.1	-0.9	1.7	-3.4	-1.6	-1.8	-0.6	-1.2	0.9
Alzheimer’s Disease (including proxy)	1.3	1.8	7.7	2.3	-0.6	1.1	0.5	2.3	1.6	1.3	0.0	0.0	1.3	2.3	2.1	0.7	0.0	1.3	0.2	1.4	2.8	-0.1	1.2	-1.1	0.6	0.9	1.0
Average weekly fortified wine intake	1.3	1.5	6.8	1.6	1.6	1.1	1.1	1.1	1.0	1.0	1.0	1.1	1.4	1.8	1.8	0.9	1.2	2.6	-0.2	0.9	0.8	0.7	0.8	0.9	0.8	0.9	1.0
Pain all over the body in last month	1.3	1.4	6.6	-1.3	-1.6	0.1	-0.8	-0.8	-0.7	-1.2	-1.4	-1.3	-0.5	-1.4	-1.4	-1.0	-2.6	-1.3	0.2	-0.9	0.1	-1.7	-0.9	-2.0	-0.5	-0.9	-1.0
Pulse wave Arterial Stiffness index	1.3	1.5	5.9	-1.6	-2.4	-1.3	-1.0	-1.2	-1.2	-1.8	-1.2	-0.9	-0.7	-1.6	-1.9	-1.2	-0.8	-0.5	-0.3	-1.2	-0.7	-0.3	-1.1	-0.4	-1.0	-1.0	-1.5
Pulse wave peak to peak time	1.3	1.5	5.7	1.7	2.4	1.3	1.2	1.2	1.2	1.8	1.3	1.0	0.7	1.7	2.0	1.1	0.8	0.4	0.2	1.1	0.8	0.2	0.9	0.6	1.0	0.9	1.6
Neck or shoulder pain in last month	1.3	1.9	7.8	-0.9	-1.6	-0.2	0.3	-0.5	0.5	0.5	0.7	0.6	-2.4	-0.9	0.4	1.6	0.8	0.7	1.8	1.2	-2.4	2.8	2.2	0.8	1.5	1.7	-1.1
Overall health rating	1.3	2.8	7.5	0.0	-1.7	1.3	1.9	1.0	1.7	1.7	1.5	1.3	0.1	-0.1	0.9	2.1	0.4	2.0	2.7	2.0	-2.3	2.2	2.7	0.4	2.3	2.3	0.1
Ever had prostate specific antigen (PSA) test	1.3	1.5	4.5	1.3	0.6	0.8	0.2	0.7	1.4	0.9	1.0	1.4	0.1	1.3	1.6	1.5	1.1	2.1	0.9	1.6	-0.0	1.6	1.7	1.1	1.3	1.5	0.6
Commuting to job workplace: Cycle	1.3	1.6	5.9	-1.0	1.5	-0.5	-1.4	-0.9	-1.4	-1.3	-1.2	-1.1	0.0	-0.9	-1.3	-1.3	-1.2	-2.4	-1.1	-1.6	0.6	-1.8	-1.7	-0.6	-1.2	-1.6	-0.4
Depression (Nagel 2018)	1.2	1.7	5.3	0.9	-0.6	0.7	1.4	1.0	0.6	1.1	1.3	1.4	0.9	0.9	0.9	1.5	2.0	2.1	1.5	0.9	-0.7	2.3	1.6	1.9	1.3	1.4	0.5
Primary Biliary Cirrhosis	1.2	1.7	3.1	-1.5	-0.9	-1.7	-1.4	-1.1	-1.8	-1.5	-1.4	-1.2	-1.4	-1.5	-1.5	-1.5	-0.1	-0.3	-1.0	-1.6	-0.3	-0.0	-1.5	-0.3	-1.6	-1.5	-1.7
Body mass index (BMI)	1.2	5.0	11.5	0.6	-1.4	2.3	2.6	2.2	2.6	2.7	2.2	2.1	-0.5	0.7	1.7	3.0	-0.2	2.1	3.1	3.0	-2.2	2.2	3.4	0.7	3.2	3.3	0.8
Arm fat percentage (right)	1.2	4.6	10.0	1.0	-1.2	2.4	2.5	2.3	2.7	2.7	2.3	2.1	0.1	1.1	1.8	2.8	0.0	2.1	2.5	2.9	-1.4	1.9	3.2	0.7	3.0	3.1	1.1
Medication: Lansoprazole	1.2	1.4	4.9	-1.7	-2.2	-1.3	-0.5	-1.3	-0.9	-0.0	-0.7	-1.0	-2.2	-2.0	-1.1	-0.4	0.2	-0.4	0.1	-0.5	-1.6	1.6	0.3	-0.2	-0.3	0.1	-1.9
Prospective memory result	1.2	1.5	7.5	0.1	-0.1	0.9	1.3	1.0	1.2	1.0	1.0	1.3	0.7	0.1	0.4	1.7	-0.0	0.6	2.7	1.5	-2.0	0.9	1.5	0.8	1.5	1.6	0.6
Illnesses of mother	1.2	1.5	2.8	-1.0	-0.1	-1.7	-1.7	-1.5	-1.4	-1.3	-1.7	-1.4	-1.0	-1.0	-1.2	-1.1	0.1	-1.6	-1.0	-1.1	0.7	-0.1	-1.2	-0.7	-1.5	-1.2	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	7.7	1.0	1.4	1.4	2.0	1.1	1.1	1.2	2.1	2.3	1.3	1.1	1.1	1.7	1.5	-1.1	2.3	1.1	-1.7	1.1	1.0	2.8	1.4	1.3	1.9
Arm fat percentage (left)	1.2	4.6	10.6	0.6	-1.5	2.2	2.6	2.1	2.5	2.7	2.2	2.0	-0.3	0.8	1.6	2.8	-0.0	1.8	2.8	2.9	-1.8	2.1	3.2	0.7	3.0	3.2	0.9
Commuting to job workplace: Walk	1.2	1.3	2.9	-0.9	0.2	-1.1	-1.1	-1.0	-1.4	-1.1	-1.2	-1.2	-1.3	-1.0	-1.0	-1.6	-0.8	-0.5	-1.7	-1.5	0.6	-1.3	-1.6	-0.6	-1.5	-1.5	-0.4
Arm fat mass (left)	1.2	4.9	9.9	1.0	-1.0	2.5	2.8	2.3	2.7	2.8	2.5	2.2	0.2	1.1	1.9	2.8	-0.1	2.0	2.7	2.9	-1.6	1.9	3.1	1.0	3.1	3.1	1.3
Ulcerative Colitis	1.1	1.5	8.8	-1.8	-3.0	-1.2	-1.0	-1.5	-0.8	-1.1	-1.3	-1.4	-1.5	-1.8	-1.4	-0.5	-0.8	0.6	0.0	-0.4	-0.6	0.4	0.0	-1.2	-0.5	-0.3	-1.8
Angina	1.1	1.5	8.1	-0.3	-1.3	1.1	1.7	0.6	0.8	0.6	1.1	0.9	-0.6	-0.5	-0.3	1.4	-0.9	-1.1	2.9	1.0	-2.4	0.8	1.4	0.4	1.6	1.3	0.2
Trunk fat mass	1.1	4.5	10.4	0.8	-1.5	2.2	2.7	2.0	2.5	2.5	2.2	2.0	0.1	0.8	1.7	2.8	0.0	1.7	2.8	2.8	-1.6	2.1	3.2	0.8	3.0	3.2	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.5	5.6	-2.2	-0.4	-1.2	-2.2	-1.4	-1.8	-1.6	-2.1	-2.3	-1.4	-1.9	-1.8	-2.1	-2.4	-1.7	-2.1	-1.9	0.7	-2.1	-2.0	-2.3	-1.9	-2.0	-1.6
Arm fat mass (right)	1.1	4.6	9.1	1.1	-0.9	2.6	2.7	2.3	2.7	2.7	2.4	2.2	0.3	1.2	1.9	2.7	-0.1	1.9	2.5	2.8	-1.3	1.7	3.0	0.8	3.0	3.0	1.3
Headache pain in last month	1.1	1.9	4.2	1.3	0.9	2.1	1.7	2.0	1.4	2.0	1.9	1.5	1.2	1.5	1.4	1.4	0.6	0.8	0.6	1.3	0.2	0.1	1.1	0.9	1.6	1.3	1.7
Medication: Ibuprofen	1.1	1.3	3.1	0.8	0.7	1.5	1.3	1.8	1.3	1.4	1.4	1.6	0.2	0.9	0.8	1.2	0.4	0.4	1.2	1.1	-1.1	0.8	1.1	1.1	1.5	1.3	1.0
Whole body fat mass	1.1	4.5	10.6	0.7	-1.6	2.3	2.6	2.0	2.5	2.5	2.1	2.0	-0.0	0.8	1.6	2.8	-0.2	1.7	2.9	2.8	-1.7	2.0	3.2	0.8	3.1	3.2	0.9
Leg fat mass (right)	1.1	4.2	9.5	0.4	-1.8	2.1	2.6	1.9	2.3	2.4	2.1	1.9	-0.2	0.5	1.3	2.7	-0.2	1.3	3.0	2.6	-2.0	2.0	3.1	0.8	2.9	3.0	0.8
Medication for cholesterol	1.1	1.7	3.7	-1.3	0.2	-1.9	-1.4	-1.6	-1.7	-1.9	-1.4	-1.2	-1.1	-1.2	-1.4	-1.4	-0.5	-0.7	-0.9	-1.5	-0.1	-0.4	-1.6	-0.5	-1.9	-1.7	-1.4
Medication: Bendroflumethiazide	1.1	1.7	3.9	0.9	-0.1	2.0	1.9	1.5	1.8	1.9	1.0	0.6	1.2	0.9	1.3	1.3	-0.7	0.8	0.9	1.6	0.5	-0.2	1.7	-0.6	1.8	1.6	1.1
Bipolar Disorder or Schizophrenia	1.0	2.4	5.8	1.4	-1.1	0.8	1.9	1.6	1.3	2.1	1.4	1.2	0.9	1.4	1.6	1.7	2.4	1.8	1.0	1.7	0.5	2.2	2.0	1.2	1.6	1.7	0.5
Prostate Cancer	1.0	1.4	5.5	-1.2	-1.7	-1.2	-0.4	-1.0	-0.6	-1.2	-1.6	-1.6	-0.6	-1.3	-1.0	-0.9	-1.1	2.3	-0.4	-0.6	0.9	0.3	-0.1	-1.8	-0.7	-0.4	-2.1
BMI	1.0	5.8	11.9	1.4	-0.4	2.9	2.4	2.9	3.2	3.1	2.3	2.4	0.0	1.6	2.3	3.2	-0.3	2.2	2.8	3.3	-1.5	1.7	3.3	0.6	3.4	3.4	1.5
Lung FVC	1.0	5.0	22.8	-3.0	-4.4	-2.4	-2.6	-1.8	-1.3	-0.8	-2.5	-2.5	-4.8	-2.8	-1.6	-0.9	-1.0	0.7	-0.8	-0.4	-0.8	1.7	0.5	-2.5	-0.9	-0.1	-3.7
Vitamin and mineral supplements	1.0	1.4	3.6	-1.9	-1.0	-1.6	-0.5	-1.4	-1.4	-1.3	-1.3	-1.5	-0.5	-1.8	-1.7	-1.3	-0.6	0.9	-0.5	-1.3	-0.4	0.0	-0.8	-0.9	-1.2	-0.9	-1.7
Medication: Co-codamol	1.0	1.1	3.7	-1.6	-0.5	-1.1	-1.5	-1.2	-1.2	-0.9	-0.8	-0.7	-1.9	-1.8	-1.2	-0.7	-0.3	-1.3	0.2	-0.9	-1.5	0.4	-0.4	-0.2	-0.6	-0.7	-1.2
Leg fat-free mass (left)	1.0	5.5	10.4	1.8	1.5	3.1	3.2	2.5	2.6	2.5	3.2	3.0	1.2	1.9	2.3	2.7	0.4	1.5	2.3	2.4	-1.5	1.0	2.4	2.3	2.9	2.6	2.8
Trunk fat percentage	1.0	3.9	9.6	0.5	-1.8	2.1	2.4	1.8	2.4	2.3	1.8	1.7	0.1	0.6	1.4	2.6	-0.3	1.4	2.8	2.7	-1.6	1.9	3.1	0.3	2.8	3.0	0.6
Relative age voice broke	1.0	1.6	7.0	0.3	1.3	-0.9	-1.7	-0.9	-1.1	-0.8	-0.8	-1.0	0.2	0.5	-0.4	-1.5	0.2	-0.3	-2.6	-1.4	1.8	-1.5	-1.9	-0.6	-1.9	-1.8	0.0
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.5	1.0	0.1	1.2	1.3	0.7	0.9	0.9	1.6	1.3	1.5	1.0	1.0	1.1	1.2	1.0	0.4	0.9	-0.5	0.7	1.2	1.6	1.3	1.2	1.5
Leg predicted mass (left)	1.0	5.5	10.9	1.8	1.4	3.1	3.3	2.5	2.6	2.5	3.1	3.0	1.2	1.8	2.3	2.7	0.4	1.5	2.3	2.4	-1.5	1.0	2.4	2.3	2.9	2.7	2.8
Hearing difficulty/problems with background noise	1.0	1.6	3.5	-1.6	1.8	-0.8	-1.1	-1.5	-1.6	-1.6	-0.6	-0.6	-1.5	-1.3	-1.4	-1.0	-0.9	-1.9	0.0	-1.6	-1.4	-1.2	-1.3	0.2	-1.0	-1.4	-0.0
Diabetes (self-reported)	1.0	1.5	6.6	-1.4	-2.1	-1.6	-1.1	-1.5	-1.3	-1.1	-1.1	-1.1	-2.6	-1.7	-1.3	-0.7	-0.2	-0.5	-0.3	-0.9	-1.0	1.1	-0.0	-0.1	-0.5	-0.3	-1.8
Exposure to tobacco smoke at home	1.0	1.1	6.2	-1.9	-0.9	-0.3	0.2	-0.5	-0.6	-0.4	-0.5	-0.4	-1.0	-1.9	-1.5	-0.2	-1.3	-1.4	1.2	-0.4	-2.5	0.1	-0.1	-0.6	0.1	-0.2	-1.2
Breastfed as a baby	1.0	1.3	3.6	1.8	-0.9	0.9	1.2	1.7	1.3	1.6	1.0	0.9	0.1	1.9	1.4	1.0	0.9	-0.1	0.1	1.2	1.5	0.4	1.0	0.6	0.9	1.1	1.1
Chronic bronchitis/emphysema (mother)	1.0	1.2	5.8	-0.3	1.2	1.3	0.7	0.4	0.3	-0.1	0.8	0.7	1.1	-0.3	-0.3	0.3	-1.9	-2.4	1.4	-0.0	-1.7	-1.9	-0.3	-0.0	0.6	-0.1	1.6
Shortness of breath walking on level ground	1.0	1.2	5.9	-0.5	-1.2	0.7	1.2	0.6	0.7	1.0	0.7	0.8	-0.6	-0.7	-0.3	1.3	-0.0	0.2	2.3	1.1	-2.4	1.3	1.3	1.0	1.3	1.4	0.3
Angina (self-reported)	1.0	1.3	7.0	-0.4	-1.5	0.9	1.7	0.4	0.7	0.6	0.9	0.7	-0.7	-0.7	-0.4	1.3	-0.9	-1.0	2.6	0.9	-2.3	0.9	1.4	0.3	1.5	1.2	-0.1
Had major operations	1.0	1.2	2.4	0.8	-1.3	0.6	1.1	0.7	1.2	1.0	1.1	1.2	-0.5	0.8	1.4	1.2	1.0	1.4	1.3	1.4	-0.6	1.6	1.4	0.7	1.1	1.4	0.3
Knee pain experienced in last month	1.0	1.5	5.4	-0.1	-0.2	0.6	1.2	-0.2	0.8	0.8	1.4	1.4	-0.2	-0.1	0.7	1.6	0.9	0.4	1.8	1.2	-2.3	1.8	1.8	1.8	1.7	1.7	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	4.2	-0.9	-1.6	-0.8	-0.7	-0.8	-0.6	-1.3	-1.7	-1.7	0.1	-0.9	-1.1	-1.1	-1.2	0.2	-0.8	-0.7	1.3	-0.8	-0.6	-2.0	-1.0	-0.8	-1.3
Illnesses of father: None of the above (group 1)	1.0	1.3	7.1	0.5	1.9	-0.3	-0.7	-0.4	-0.6	-0.6	-0.9	-1.0	1.5	0.6	0.1	-1.1	0.3	0.4	-1.8	-0.9	2.7	-1.3	-1.3	-0.9	-1.4	-1.3	0.1
Hearing aid user	1.0	1.1	2.9	0.6	-0.8	0.5	1.2	0.8	0.5	0.5	1.2	1.4	-0.4	0.5	0.8	1.1	1.7	1.1	1.4	0.8	-1.4	1.4	1.1	1.7	1.1	0.9	0.7
HDL Cholesterol	0.9	1.4	4.3	1.4	1.6	1.1	1.6	1.7	0.7	1.6	1.5	1.9	1.2	1.4	0.8	0.9	0.9	-0.2	0.5	0.5	-0.8	0.5	0.2	2.1	0.8	0.6	1.1
Supplements: Zinc	0.9	1.0	2.8	1.2	0.6	1.7	1.1	1.4	1.0	0.8	1.2	1.4	0.5	1.1	0.5	0.8	0.2	-1.2	0.8	0.6	-0.1	-0.5	0.3	1.0	1.1	0.6	1.6
Hayfever, allergic rhinitis or eczema	0.9	2.0	4.1	-1.2	0.8	-1.3	-2.0	-1.4	-1.7	-1.4	-1.4	-1.6	-1.2	-1.2	-1.4	-1.7	-0.9	-0.0	-1.7	-1.7	0.4	-1.2	-1.9	-0.7	-1.9	-1.8	-0.7
Hair/balding pattern: Pattern 2	0.9	1.1	4.8	-0.6	-1.5	-0.6	0.2	-0.5	-0.3	-0.6	-1.4	-1.7	0.6	-0.5	-0.8	-0.9	-1.2	1.1	-1.2	-0.3	1.8	-0.7	-0.5	-2.2	-0.9	-0.6	-1.2
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	5.1	0.3	0.3	-0.3	0.7	0.0	0.2	0.5	1.1	1.2	-0.5	0.2	0.4	1.0	2.2	0.3	1.2	0.6	-1.3	2.2	1.1	2.2	0.7	0.9	0.1
Qualifications: None of the above	0.9	1.9	5.0	0.5	-1.1	1.0	2.2	1.3	1.4	1.4	1.4	1.4	1.3	0.5	1.0	1.7	0.8	1.7	1.5	1.6	-1.4	1.3	1.8	0.9	1.8	1.7	0.9
Mouth/teeth dental problems	0.9	1.3	5.1	-1.2	1.0	-0.5	-1.4	-1.3	-1.2	-1.3	-1.1	-0.9	-2.2	-1.2	-1.0	-0.9	-0.9	-2.0	-0.7	-1.2	-0.1	-0.8	-1.2	-0.3	-0.9	-1.1	-0.8
Weight	0.9	4.6	8.8	1.3	-0.3	2.6	2.8	2.3	2.6	2.6	2.5	2.4	0.4	1.4	2.0	2.7	0.1	1.7	2.5	2.6	-1.3	1.6	2.9	1.3	3.0	3.0	1.7
Alcohol intake versus 10 years previously	0.9	1.3	5.1	0.3	-2.3	-0.2	1.6	-0.2	0.5	1.1	0.9	0.7	-0.3	0.2	0.8	1.1	2.1	1.4	0.6	1.0	-0.9	2.0	1.5	1.0	0.9	1.2	0.3
Blood clot in the leg (DVT)	0.9	1.1	5.2	-0.2	-1.5	0.6	0.6	0.6	1.1	0.9	0.3	0.4	-0.9	-0.3	0.2	1.5	-0.8	-0.7	2.3	1.5	-1.3	1.1	1.5	-0.5	1.3	1.6	-0.5
Body fat percentage	0.9	3.5	9.2	0.2	-2.1	1.8	2.1	1.6	2.2	2.1	1.6	1.5	-0.4	0.3	1.1	2.5	-0.4	1.3	2.8	2.5	-1.8	2.0	3.0	0.2	2.7	2.9	0.3
Leg fat-free mass (right)	0.9	4.7	9.1	1.8	1.5	3.0	3.0	2.4	2.5	2.4	2.9	2.7	1.2	1.8	2.2	2.4	0.2	1.3	2.0	2.2	-1.2	0.6	2.1	1.9	2.7	2.4	2.7
Ever had bowel cancer screening	0.9	1.1	4.0	-0.9	-1.4	-0.7	-2.0	-1.5	-1.0	-1.6	-1.4	-1.2	-0.6	-1.0	-1.0	-1.0	-0.6	-0.0	-0.7	-1.0	0.2	-0.3	-0.7	-1.0	-0.8	-0.8	-1.0
Leg predicted mass (right)	0.9	4.8	9.3	1.8	1.5	3.0	3.1	2.4	2.5	2.4	2.9	2.7	1.2	1.9	2.3	2.4	0.2	1.3	2.0	2.3	-1.2	0.7	2.2	1.9	2.7	2.4	2.7
High cholesterol (Self-reported)	0.9	1.6	6.4	-1.6	-2.5	-1.3	-0.8	-1.0	-0.3	-0.8	-1.7	-1.7	-1.5	-1.7	-1.3	-0.7	-1.3	-0.7	0.0	-0.2	0.2	0.1	0.2	-2.4	-0.7	-0.2	-2.0
Cholesterol lowering medication	0.9	1.3	3.0	1.1	-1.0	1.0	1.2	1.0	1.6	1.2	0.9	0.8	0.9	1.1	1.3	1.4	0.8	1.1	0.9	1.7	0.4	0.9	1.7	-0.0	1.4	1.6	0.8
Alcohol drinker status: Previous	0.9	1.0	4.3	-1.4	0.3	-0.9	-0.9	-1.0	-1.3	-0.8	-0.5	-0.3	-1.0	-1.5	-1.4	-0.7	-0.3	-2.1	0.1	-1.1	-1.6	-0.4	-1.0	0.6	-0.7	-0.9	-0.2
Pack years of smoking	0.9	1.3	4.7	-1.7	-2.2	-1.1	-0.7	-1.5	-0.6	-0.7	-0.8	-0.7	-1.8	-2.0	-1.3	-0.1	-0.8	-0.6	0.9	-0.2	-1.9	1.0	0.3	-0.3	-0.2	0.2	-1.4
Leg fat mass (left)	0.9	3.5	8.3	0.2	-1.9	1.9	2.4	1.7	2.1	2.2	1.8	1.6	-0.4	0.3	1.2	2.5	-0.3	1.2	2.8	2.4	-1.8	1.9	2.9	0.6	2.7	2.8	0.5
Schizophrenia (2018)	0.8	1.6	4.6	1.1	-0.6	0.9	2.1	1.2	1.0	1.8	1.5	1.2	0.2	1.1	1.3	1.3	1.9	0.6	0.8	1.1	0.0	1.5	1.5	1.3	1.4	1.4	0.9
HbA1C	0.8	0.9	2.2	0.2	-0.9	0.3	1.1	0.2	1.3	0.8	0.7	0.8	-0.6	0.2	0.7	1.1	0.7	0.2	1.2	1.3	-1.1	1.4	1.5	0.6	1.2	1.4	-0.0
Pulse rate	0.8	1.3	4.6	-1.9	-2.1	-1.2	-0.2	-1.0	-0.9	-0.4	-1.0	-1.2	-1.5	-1.8	-1.5	-0.8	-1.5	0.3	-0.3	-0.8	-0.9	-0.1	-0.6	-1.1	-0.7	-0.6	-1.9
Qualifications: A levels/AS levels or equivalent	0.8	1.7	7.1	-1.3	-0.6	-1.3	-2.4	-1.4	-1.1	-1.3	-1.6	-1.2	-2.7	-1.4	-1.2	-0.9	-1.0	-1.1	-0.6	-0.8	-0.5	-0.1	-0.9	-1.1	-1.0	-0.9	-1.9
Tense / ‘highly strung’	0.8	1.3	9.1	-1.8	-3.0	-1.1	-0.8	-1.1	-0.5	-0.2	-1.0	-1.3	-0.9	-1.8	-1.3	-0.0	-0.4	-0.8	0.5	-0.0	-0.6	0.9	0.7	-1.3	0.1	0.3	-1.8
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	5.6	-0.7	-0.6	-1.7	-1.0	-1.2	-1.8	-0.6	-0.6	-0.5	-2.4	-0.7	-0.9	-1.0	1.5	-0.2	-0.9	-1.4	-0.3	1.0	-1.1	1.1	-1.4	-1.2	-1.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.9	0.7	-0.3	0.6	2.0	1.0	0.8	1.1	1.3	1.1	1.0	0.7	0.6	1.2	0.9	0.9	1.3	1.0	-0.8	0.7	1.2	1.1	1.1	1.0	1.2
Medication: Aspirin	0.8	1.1	3.8	-1.7	-1.5	-0.8	-0.2	-1.2	-0.4	-0.9	-0.7	-0.8	-1.3	-2.0	-1.4	-0.4	-1.0	-0.4	0.8	-0.3	-1.9	0.5	0.3	-0.9	-0.0	0.0	-1.5
Illnesses of siblings: Diabetes	0.8	1.0	4.5	-1.4	-2.1	-0.8	-0.7	-0.4	-0.3	-0.5	-1.0	-1.0	-1.3	-1.4	-1.2	-0.3	-1.0	0.3	-0.0	-0.2	-0.9	0.4	0.2	-1.5	-0.0	-0.0	-1.9
Loneliness, isolation	0.8	1.1	2.6	0.9	0.2	1.1	1.6	1.4	1.1	1.2	1.2	1.0	1.1	1.0	1.1	1.1	0.6	1.2	0.9	1.1	0.0	0.8	1.2	0.5	1.2	1.1	0.6
Mother’s age at death	0.8	1.0	3.3	0.2	0.1	-0.4	-0.7	-0.2	-0.6	-0.9	-1.0	-1.2	1.2	0.1	-0.6	-1.2	-0.8	1.5	-1.4	-1.0	1.8	-1.4	-1.2	-1.3	-1.2	-1.1	-0.2
Bipolar Disorder (2018)	0.7	1.1	5.1	0.9	-1.0	0.2	0.4	1.1	0.8	1.1	0.4	0.5	1.2	0.9	0.9	1.1	1.5	2.3	0.7	1.3	0.8	1.6	1.4	0.2	0.8	1.0	-0.3
Age at First Birth	0.7	1.0	7.2	0.7	2.7	0.6	-0.3	0.2	-0.4	-0.5	0.5	0.2	1.8	0.7	0.1	-0.8	-0.1	-0.5	-0.7	-0.9	0.7	-1.7	-1.5	0.2	-0.6	-1.1	1.0
Lupus	0.7	1.1	4.6	0.6	-0.2	0.0	1.4	0.7	0.5	1.1	1.2	1.2	-0.4	0.8	0.7	0.9	2.1	0.1	0.8	0.7	-1.2	2.0	1.1	1.5	0.8	1.0	-0.1
Rheumatoid Arthritis	0.7	0.9	6.8	0.4	2.6	1.0	0.4	0.3	-0.2	0.2	1.0	0.9	0.5	0.5	-0.0	-0.3	-0.5	-2.0	0.0	-0.7	-0.2	-1.5	-0.9	1.1	-0.1	-0.6	1.5
Allergy or Eczema	0.7	1.9	4.5	-1.3	0.6	-1.8	-2.0	-1.2	-2.0	-1.1	-1.2	-1.3	-0.9	-1.3	-1.5	-1.7	0.1	0.5	-1.9	-1.8	-0.1	-0.6	-1.9	0.1	-2.1	-1.9	-0.6
Pack years adult smoking proportion	0.7	1.0	4.7	-1.4	-2.2	-0.7	-0.2	-1.1	-0.1	-0.3	-0.6	-0.5	-1.6	-1.7	-1.0	0.3	-0.8	-0.1	1.2	0.3	-1.9	1.2	0.7	-0.4	0.2	0.6	-1.3
Hand grip strength (right)	0.7	1.9	7.7	1.9	2.8	1.1	0.5	1.4	1.1	0.4	0.2	0.2	2.8	2.0	1.4	0.2	0.1	-1.1	-0.9	0.5	2.5	-1.6	-0.2	-0.7	0.1	0.0	1.8
Impedance of leg (left)	0.7	3.5	7.0	-1.3	-1.4	-2.4	-2.1	-1.9	-2.1	-2.0	-2.3	-2.2	-0.1	-1.3	-1.8	-2.1	-0.2	-2.6	-1.6	-2.1	1.7	-0.9	-2.0	-1.4	-2.4	-2.1	-2.1
Hip circumference	0.7	2.9	6.8	1.3	0.5	2.6	2.1	2.1	2.1	1.9	2.1	2.0	0.7	1.5	1.8	1.9	-0.3	0.9	1.7	1.9	-0.6	0.4	1.8	0.9	2.2	2.0	1.9
Time employed in main current job	0.7	0.8	2.8	-0.1	1.1	-0.3	-0.4	-0.5	-1.2	-0.7	-0.2	-0.5	0.5	-0.1	-0.8	-1.1	-0.4	-0.8	-1.7	-1.4	0.8	-1.3	-1.3	0.1	-0.8	-1.4	-0.2
Happiness	0.7	0.8	2.4	-0.2	-0.4	-1.5	0.0	-0.9	-1.0	-0.1	-0.2	-0.4	-1.4	-0.1	0.1	-0.7	1.3	0.7	-1.5	-0.8	0.6	1.2	-0.6	0.6	-1.2	-0.8	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.5	0.2	-1.2	1.3	1.1	1.4	1.2	1.0	0.7	0.6	1.4	0.1	-0.0	0.9	-1.2	-1.3	1.9	0.9	-0.8	-0.2	1.0	-0.8	1.3	1.0	0.1
Leg fat percentage (right)	0.7	2.4	6.8	-0.6	-2.5	1.1	1.5	1.0	1.4	1.5	1.1	1.0	-1.0	-0.5	0.4	2.0	-0.3	0.7	2.6	1.8	-2.1	2.0	2.5	0.1	2.2	2.3	-0.3
Number of children fathered	0.7	0.8	1.9	0.6	-0.5	0.2	1.4	0.4	0.8	1.0	1.2	1.1	0.2	0.5	1.0	1.0	1.0	0.9	0.9	0.8	-1.0	1.3	1.2	0.9	0.9	1.1	0.5
Supplements: Vitamin C	0.7	0.8	2.4	0.3	-1.5	0.1	0.9	0.5	0.5	1.2	0.9	0.8	-1.0	0.2	0.7	1.1	0.6	-0.6	1.2	0.9	-1.0	1.5	1.2	1.0	0.9	1.0	-0.3
Osteoporosis (self-reported)	0.7	0.9	4.1	-1.4	0.2	-0.8	-0.8	-1.4	-1.3	-0.7	-0.2	-0.5	-0.2	-1.3	-1.1	-0.7	-0.5	-2.0	-0.1	-1.2	-1.0	-0.7	-0.9	0.4	-0.7	-0.9	-0.0
Guilty feelings	0.7	1.1	2.3	1.0	0.6	1.5	0.9	1.2	1.3	0.9	1.2	1.3	0.6	1.2	1.5	1.1	0.1	0.1	0.9	1.2	-0.7	0.3	1.1	0.6	1.5	1.2	1.1
Eye problems/disorders: Glaucoma	0.7	0.8	2.2	1.1	0.9	1.0	0.4	0.6	1.2	0.4	0.8	1.0	0.6	1.2	1.5	0.9	0.3	1.2	0.6	1.1	0.4	0.2	1.0	0.2	1.1	1.0	0.9
Medication: Paracetamol	0.7	1.1	1.9	1.2	0.7	1.1	0.4	0.7	1.3	1.0	1.0	1.2	0.5	1.2	1.4	1.2	1.3	0.8	0.6	1.3	0.1	0.7	1.3	0.8	1.3	1.3	1.3
Irritability	0.7	1.2	3.8	-1.9	-1.2	-0.8	-0.7	-1.1	-0.7	-1.1	-0.9	-0.8	-1.7	-1.8	-1.5	-0.4	-0.6	-1.1	1.3	-0.5	-1.9	0.6	-0.1	-0.6	-0.2	-0.2	-1.2
Unable to work because of sickness or disability	0.7	1.0	5.1	-0.8	-1.6	-0.9	1.0	-0.5	-0.5	0.6	0.3	0.2	-1.1	-0.9	-0.2	0.3	1.5	1.3	0.7	0.2	-1.6	2.3	0.7	1.0	0.1	0.5	-1.1
Myopia	0.7	1.0	3.6	0.4	-0.2	1.4	1.4	1.9	0.6	0.7	1.2	1.5	0.8	0.5	-0.2	0.8	0.3	0.2	1.4	0.4	-1.7	0.2	0.3	1.2	1.2	0.6	0.8
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	4.2	-0.4	-1.3	0.5	0.5	0.4	1.0	0.6	0.0	0.2	-0.9	-0.4	-0.1	1.2	-1.1	-0.8	2.1	1.3	-1.4	0.7	1.1	-0.7	1.0	1.3	-0.5
Schizophrenia (2014)	0.6	1.3	2.7	0.6	-1.3	1.1	1.4	1.0	1.1	1.4	1.1	1.1	0.2	0.6	0.8	1.4	1.1	-0.0	1.4	1.2	-0.4	1.3	1.6	0.8	1.6	1.5	0.7
Hand grip strength (left)	0.6	1.5	7.7	1.7	2.3	1.1	0.5	1.2	0.9	0.6	0.5	0.3	2.8	1.6	1.3	0.2	-0.0	-1.0	-0.9	0.4	2.0	-1.4	-0.1	-0.4	0.3	0.0	1.7
Sensitivity / hurt feelings	0.6	1.1	5.3	-1.5	-0.9	0.2	-0.8	-0.3	-0.2	-0.5	-0.7	-0.9	-0.9	-1.3	-1.3	-0.6	-2.3	-2.0	0.2	-0.6	-0.5	-1.2	-0.4	-1.6	-0.0	-0.4	-1.0
Frequency of depressed mood in last 2 weeks	0.6	0.8	3.4	-1.0	-0.7	-0.8	-0.0	-1.0	-1.2	-0.4	0.2	0.2	-0.7	-0.9	-0.8	0.0	1.4	0.9	0.4	-0.7	-1.9	1.8	0.2	1.5	0.0	-0.1	-0.8
Stomach or abdominal pain in last month	0.6	0.7	1.5	0.8	0.1	1.1	0.5	0.4	1.1	0.7	0.8	0.6	0.8	0.7	1.1	1.2	-0.1	-0.6	1.1	1.0	0.0	0.1	1.1	0.1	1.2	1.2	1.0
High blood pressure (mother)	0.6	0.9	3.6	0.9	0.9	1.5	1.1	0.8	0.7	0.9	1.5	1.2	1.3	1.0	0.9	0.5	-0.0	-0.4	0.4	0.4	-0.2	-0.9	0.2	1.0	0.8	0.4	1.9
Number of incorrect matches in round	0.6	0.9	2.8	0.9	1.6	1.7	1.0	1.2	1.1	0.8	1.0	1.0	1.2	1.1	0.9	0.9	0.1	0.1	0.9	0.7	-0.0	-0.2	0.7	0.4	1.3	0.9	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.1	-1.5	-0.7	-0.8	-0.2	-1.1	-1.3	-0.1	0.1	-0.4	-1.3	-1.5	-1.2	-0.1	0.5	-0.2	0.6	-1.0	-1.8	1.2	-0.0	0.8	-0.0	-0.4	-1.3
Allergy	0.6	1.3	2.8	1.4	-0.3	1.2	1.7	1.2	1.4	0.9	1.3	1.4	1.2	1.5	1.5	1.2	0.9	0.5	0.8	1.2	0.3	0.6	1.3	0.7	1.4	1.3	0.9
Glaucoma (self-reported)	0.6	0.7	1.9	1.3	0.8	1.1	0.6	1.0	0.9	0.5	0.8	0.8	1.1	1.4	1.3	0.6	-0.2	1.2	0.1	0.7	1.0	-0.3	0.6	0.1	0.8	0.6	0.8
Medication: Amlodipine	0.6	0.8	2.3	-1.4	-0.4	-0.9	-0.7	-1.1	-1.3	-0.8	-0.8	-0.9	-1.5	-1.5	-1.2	-0.9	-0.2	-0.1	-0.7	-1.2	-0.4	-0.1	-0.8	0.0	-0.9	-0.9	-0.7
Number of full brothers	0.6	0.7	3.9	-1.3	-0.7	-0.5	0.0	-0.3	-1.0	-0.6	-0.0	0.0	-1.4	-1.4	-1.4	-0.5	-0.3	0.7	0.3	-0.9	-2.0	0.6	-0.4	0.8	-0.2	-0.4	-1.0
Medication for pain relief, constipation, heartburn	0.6	1.0	3.0	0.2	1.7	-0.5	-0.9	-0.7	-1.0	-0.8	-0.7	-0.7	1.0	0.2	-0.0	-1.1	-0.3	-0.5	-1.7	-1.1	1.5	-1.6	-1.5	-0.2	-1.3	-1.4	0.5
Number of full sisters	0.6	0.7	2.4	-1.0	-1.5	0.3	-0.6	-0.1	0.2	-0.6	-0.9	-0.8	0.1	-1.2	-1.1	-0.1	-1.5	-1.3	1.1	0.0	-0.4	-0.6	0.1	-1.6	0.3	0.1	-0.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.0	1.4	0.9	0.6	0.7	0.4	0.5	0.2	0.4	0.5	1.7	1.4	1.3	0.2	0.9	0.7	-0.7	0.4	1.5	-0.2	-0.2	0.5	-0.0	0.0	1.0
Friendships satisfaction	0.6	0.7	3.3	-1.3	-1.4	-0.9	-0.2	-0.6	-0.6	-0.6	-0.9	-0.8	-1.8	-1.1	-0.7	-0.4	-0.4	0.6	-0.1	-0.3	-0.2	0.5	-0.1	-0.9	-0.5	-0.2	-1.6
Basal metabolic rate	0.6	3.5	6.6	1.5	1.0	2.5	2.6	2.0	2.1	2.2	2.5	2.3	0.7	1.5	2.0	2.1	0.4	1.3	1.6	1.9	-0.9	1.0	2.0	1.7	2.4	2.2	2.1
Neuroticism (Nagel 2018)	0.5	1.1	3.4	0.4	-0.2	1.3	1.2	0.9	1.3	0.9	1.1	1.2	0.4	0.5	0.6	1.3	0.4	-0.2	1.8	1.2	-1.5	0.9	1.4	0.5	1.7	1.5	0.6
Triglycerides	0.5	0.8	3.2	-1.0	-0.9	-1.3	-0.9	-1.8	-0.9	-1.3	-0.9	-1.2	-0.4	-1.1	-0.7	-0.8	0.7	-0.2	-0.8	-0.8	0.6	0.3	-0.3	-0.5	-0.8	-0.5	-0.8
Average weekly spirits intake	0.5	0.7	3.4	-1.0	-1.0	-0.5	-0.8	-0.1	-0.3	-0.4	-1.0	-0.9	-0.6	-1.1	-1.1	-0.6	-1.9	-0.3	0.2	-0.4	-0.6	-0.5	-0.4	-1.4	-0.4	-0.4	-1.1
Hearing difficulty/problems: Yes	0.5	0.7	6.4	-1.2	-0.2	0.1	0.0	-0.1	-0.8	-0.6	0.3	0.4	-1.1	-1.2	-1.2	-0.3	-0.8	-0.8	1.0	-0.9	-2.5	-0.3	-0.6	0.8	-0.0	-0.6	0.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	3.2	0.1	0.1	-0.6	-0.7	-0.9	-0.4	-0.7	-0.7	-0.8	-0.3	0.2	-0.1	-0.7	-0.0	-1.3	-1.2	-0.6	1.8	-0.8	-0.5	-0.9	-0.8	-0.7	-0.3
Current tobacco smoking	0.5	0.8	4.0	0.1	-1.2	-0.3	0.2	-0.4	0.7	0.3	0.3	0.4	-0.5	-0.1	0.8	0.9	1.4	1.5	0.8	1.0	-0.6	2.0	1.6	0.4	0.8	1.3	-0.5
Age when periods started (menarche)	0.5	1.1	4.0	-0.7	-2.0	-0.8	1.2	-0.7	-0.4	0.7	0.6	0.5	-1.5	-0.9	-0.4	0.7	1.4	-0.6	1.2	0.3	-1.9	1.9	0.8	1.7	0.3	0.7	-0.2
Serious illness, injury or assault to yourself	0.5	0.6	2.8	-0.8	-1.0	-0.8	-0.0	-0.6	-0.8	-0.4	-0.5	-0.5	-1.7	-0.8	-1.0	-0.6	-0.4	-0.3	-0.2	-0.7	0.1	0.2	-0.4	-0.5	-0.6	-0.6	-1.5
Had other major operations	0.5	0.6	1.7	-0.8	-0.3	-1.3	-1.3	-1.2	-1.0	-0.3	-0.6	-0.8	-1.3	-0.8	-0.5	-0.4	0.1	-0.1	-0.9	-0.5	-0.3	0.5	-0.2	-0.1	-0.6	-0.4	-1.0
Heart attack	0.5	0.7	4.0	-0.8	-1.0	-0.8	-0.0	-0.7	-0.3	-0.1	-0.2	-0.1	-2.0	-1.0	-0.5	0.4	0.2	-0.7	0.9	0.1	-1.6	1.3	0.5	0.3	0.2	0.3	-1.1
Number of live births	0.5	0.7	5.5	-0.5	-0.2	0.3	0.8	-0.1	0.1	0.3	0.9	0.8	0.6	-0.5	-0.0	0.7	0.9	0.2	1.0	0.3	-2.3	1.0	0.6	1.3	0.9	0.7	0.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	4.7	-1.2	-0.3	-0.6	-1.2	-0.6	-0.9	-1.0	-1.5	-1.7	-0.5	-1.0	-1.3	-1.4	-2.1	-1.4	-1.4	-1.1	1.2	-2.1	-1.4	-2.2	-1.3	-1.4	-0.8
Lung cancer (father)	0.5	0.6	2.6	1.1	0.5	-0.4	0.1	0.5	0.1	0.6	0.4	0.5	0.3	1.1	1.1	0.4	1.6	1.3	-0.5	0.3	0.8	1.5	0.4	0.9	-0.0	0.3	-0.4
Worry too long after embarrassment	0.5	0.8	2.4	-1.5	-0.9	-0.3	-1.5	-1.3	-0.3	-0.9	-0.8	-0.8	-1.6	-1.4	-0.8	-0.4	-0.9	-0.5	-0.2	-0.4	-0.9	0.1	0.1	-1.1	0.1	-0.1	-1.3
Qualifications: College or University degree	0.5	1.6	4.8	-0.8	-0.2	-1.9	-2.2	-1.5	-1.4	-1.2	-1.4	-1.3	-1.9	-0.7	-0.7	-1.4	-0.2	-0.5	-1.5	-1.3	0.9	-0.2	-1.3	-0.7	-1.7	-1.3	-1.5
Medication: Omeprazole	0.5	0.6	1.8	-0.7	-0.9	-1.3	-1.0	-0.5	-0.7	-0.4	-1.1	-1.0	-0.5	-0.7	-0.8	-0.3	0.4	0.6	-0.4	-0.3	0.5	0.7	0.2	-0.9	-0.7	-0.3	-1.3
Medication: Seretide 50 evohaler	0.5	0.6	2.5	-0.6	1.0	-0.6	-0.5	-0.7	-0.8	-0.3	0.2	0.4	-0.4	-0.6	-0.8	-0.1	1.6	-0.1	0.3	-0.6	-1.4	1.1	-0.4	1.6	-0.2	-0.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.4	0.7	0.5	1.9	1.1	1.0	0.6	-0.0	0.9	1.1	0.5	0.7	0.2	0.4	-0.7	-0.4	0.9	0.2	-0.7	-1.0	-0.1	0.5	0.9	0.3	1.3
Whole body fat-free mass	0.5	3.0	5.8	1.6	1.4	2.3	2.4	1.8	1.8	1.9	2.4	2.2	0.9	1.6	1.9	1.8	0.6	1.3	1.2	1.6	-0.6	0.7	1.7	1.8	2.0	1.8	2.1
Breast cancer (self-reported)	0.5	0.6	4.6	-0.1	2.1	-0.0	-1.3	-0.1	-0.2	-0.3	-0.3	-0.4	1.5	-0.1	-0.4	-0.3	-0.8	-0.7	-0.0	-0.4	0.5	-1.3	-0.4	-0.8	-0.2	-0.5	0.2
Medication: Aspirin	0.5	0.6	2.0	-1.3	-0.9	-0.3	-0.0	-0.8	-0.1	-0.7	-0.6	-0.7	-0.6	-1.4	-1.1	-0.3	-1.1	-0.6	0.7	-0.2	-1.4	0.1	0.2	-1.1	0.1	0.0	-1.1
Whole body water mass	0.5	3.1	6.1	1.6	1.4	2.3	2.4	1.8	1.9	1.9	2.5	2.2	1.0	1.6	2.0	1.9	0.6	1.3	1.2	1.6	-0.6	0.7	1.7	1.9	2.1	1.8	2.3
Miserableness	0.5	0.9	2.4	0.3	0.8	1.6	0.9	1.1	1.0	0.7	1.1	0.9	0.8	0.2	0.5	0.8	-0.1	-1.1	1.6	0.7	-1.3	-0.0	0.7	0.3	1.3	1.0	1.0
Leg fat percentage (left)	0.5	1.9	6.6	-0.9	-2.6	0.8	1.1	0.7	1.1	1.1	0.6	0.5	-1.3	-0.7	0.1	1.6	-0.7	0.4	2.3	1.5	-1.9	1.8	2.2	-0.3	1.8	1.9	-0.7
Fractured/broken bones in last 5 years	0.5	0.7	4.1	-0.1	1.0	0.7	-0.8	0.4	-0.0	-0.5	-0.5	-0.6	0.5	0.0	-0.5	-0.5	-1.4	-1.2	-0.7	-0.3	0.5	-2.0	-0.7	-1.3	-0.2	-0.7	0.8
Heart disease (siblings)	0.5	0.6	2.2	-1.1	-1.5	-0.4	-0.4	-0.9	-0.5	-0.6	-0.7	-0.5	-1.5	-1.3	-1.0	-0.1	-0.0	0.2	0.6	-0.2	-1.4	0.5	0.2	-0.1	-0.0	0.1	-0.3
Crohns Disease (2017)	0.4	1.0	2.9	0.8	0.5	1.2	0.6	0.6	1.4	0.5	0.3	0.6	0.1	0.7	1.1	1.2	0.0	1.7	1.2	1.5	1.2	0.7	1.5	-0.3	1.2	1.4	0.1
Ovarian Cancer	0.4	0.5	1.3	0.8	-0.5	0.7	0.9	0.8	1.1	0.6	0.2	0.3	0.5	0.9	0.8	0.8	-0.3	0.2	0.6	1.1	0.6	0.2	0.8	-0.5	0.7	0.8	0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.1	-0.3	-0.8	0.3	-0.1	-0.3	0.6	0.1	0.5	0.4	-0.1	-0.6	-0.3	0.7	-0.4	0.8	1.4	0.6	-1.4	0.7	1.0	0.3	0.9	1.1	0.1
Impedance of leg (right)	0.4	1.8	5.2	-0.9	-1.1	-1.9	-1.4	-1.4	-1.7	-1.5	-1.5	-1.4	0.3	-0.9	-1.3	-1.5	0.5	-2.3	-1.0	-1.6	1.2	-0.4	-1.4	-0.6	-1.7	-1.6	-1.4
Maternal smoking around birth	0.4	0.5	1.9	0.4	-0.8	0.0	1.2	0.8	0.3	0.6	0.9	0.8	0.4	0.1	0.4	0.6	0.6	-0.3	1.4	0.4	-1.2	1.2	0.7	0.9	0.5	0.4	-0.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	0.2	-0.1	1.0	0.4	0.5	0.9	0.6	0.7	0.5	-0.1	0.0	0.5	0.8	-0.3	-0.1	1.2	0.9	-1.0	0.3	1.1	-0.2	1.2	1.0	0.4
Qualifications: CSEs or equivalent	0.4	0.6	2.2	-1.2	0.7	-0.2	-0.1	-0.3	-0.9	0.1	-0.1	-0.3	-0.5	-1.2	-1.2	-0.6	-1.2	-1.3	-0.0	-0.9	-1.5	-0.6	-0.7	-0.1	-0.3	-0.7	-0.4
Waist circumference	0.4	1.6	8.2	-1.6	-2.9	-0.2	0.2	-0.4	0.3	0.3	-0.3	-0.5	-2.0	-1.6	-0.6	0.7	-0.9	1.6	1.1	0.7	-1.6	1.7	1.5	-0.9	0.8	1.1	-1.7
Medication: Simvastatin	0.4	0.5	2.8	-1.0	-1.7	-0.4	-0.2	-0.4	-0.1	-0.3	-0.7	-0.8	-1.0	-1.1	-0.8	-0.3	-1.0	-0.2	0.1	-0.0	-0.6	-0.2	0.2	-1.3	0.1	0.0	-0.8
Hair/balding pattern: Pattern 3	0.4	0.6	3.9	0.1	0.4	1.1	-0.3	0.6	0.7	-0.0	-0.1	-0.1	0.2	0.1	0.2	0.1	-2.0	-1.7	0.3	0.4	0.5	-1.5	-0.0	-1.1	0.5	0.2	0.5
Mouth/teeth dental problems: Dentures	0.4	0.7	4.6	1.2	-0.2	0.5	0.6	0.7	0.7	0.3	-0.1	-0.2	1.9	1.1	0.8	-0.3	-0.3	0.5	-0.6	0.3	2.1	-1.0	-0.1	-1.0	-0.2	-0.0	0.5
Ever highly irritable/argumentative for 2 days	0.4	0.5	4.9	-0.6	-2.2	0.1	0.7	0.2	0.3	0.5	0.0	-0.2	-0.3	-0.6	-0.2	0.3	-0.7	-0.2	0.6	0.3	-1.0	0.6	0.6	-0.8	0.5	0.5	-0.8
Loud music exposure frequency	0.4	0.5	1.8	0.6	1.3	-0.8	-0.4	-0.4	-0.8	-0.1	0.1	-0.0	-0.2	0.7	0.3	-0.4	1.3	-1.0	-1.1	-0.5	0.6	0.1	-0.7	0.9	-0.7	-0.8	0.1
Medication: Ventolin 100micrograms inhaler	0.4	0.5	3.8	0.3	1.5	-0.2	-0.5	0.1	-0.4	0.3	0.7	0.6	-0.1	0.4	0.1	-0.0	1.9	-0.7	-0.6	-0.4	-0.2	0.6	-0.1	1.4	-0.1	-0.3	0.7
High blood pressure (siblings)	0.4	0.6	2.4	-0.8	-0.3	-0.2	-1.0	-1.3	-0.5	-1.3	-0.5	-0.6	-0.4	-0.8	-0.9	-0.7	-0.5	-1.6	-0.2	-0.7	0.1	-1.0	-0.6	-0.7	-0.4	-0.7	0.0
Arm fat-free mass (right)	0.4	1.8	4.1	0.8	0.4	1.6	2.0	1.1	1.3	1.7	1.9	1.6	0.2	0.8	1.3	1.6	0.5	1.0	1.3	1.3	-0.8	1.1	1.7	1.5	1.8	1.6	1.3
Age at first live birth	0.4	0.7	6.1	1.0	2.5	0.7	-0.2	0.3	0.3	-0.6	0.4	0.8	0.9	1.0	0.7	-0.1	0.2	0.3	-0.6	-0.1	1.0	-1.0	-0.7	0.6	-0.0	-0.3	1.1
Health satisfaction	0.4	0.6	3.5	-0.4	-0.2	0.4	1.0	-0.1	0.1	0.3	1.0	1.1	-0.9	-0.2	0.0	0.6	0.8	0.3	1.0	0.2	-1.9	1.1	0.4	1.4	0.6	0.5	0.1
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.4	-0.8	-1.0	-0.5	-0.5	-1.0	-0.2	-0.9	-0.5	-0.2	-0.4	-0.9	-0.6	-0.2	0.2	1.5	-0.2	-0.2	-0.9	0.9	0.0	-0.2	-0.1	0.1	-1.3
Emphysema/chronic bronchitis	0.4	0.4	1.0	0.5	-0.7	0.5	1.0	0.7	0.8	0.8	0.3	0.3	0.7	0.5	0.8	0.7	-0.0	0.3	0.6	0.8	0.2	0.7	0.9	-0.4	0.7	0.7	-0.2
Migraine (self-reported)	0.4	0.5	2.9	-0.3	0.2	0.1	0.9	0.1	-0.3	0.6	0.8	0.8	-0.5	-0.4	-0.4	0.5	1.0	0.2	0.7	-0.0	-1.4	0.9	0.3	1.7	0.4	0.4	0.3
Arm predicted mass (right)	0.4	1.8	3.6	0.9	0.6	1.7	1.9	1.3	1.4	1.6	1.8	1.6	0.2	0.9	1.4	1.7	0.3	0.8	1.4	1.3	-0.9	1.0	1.7	1.4	1.9	1.7	1.3
Pulse rate, automated reading	0.4	1.4	9.5	-1.3	-3.1	-1.4	0.8	-0.4	-0.2	0.6	-0.7	-0.9	-1.7	-1.4	-0.9	0.1	-0.2	1.5	0.3	0.3	-0.5	1.7	0.7	-1.0	-0.1	0.5	-2.4
Smoking status: Previous	0.4	0.6	2.3	0.8	1.5	0.8	-0.1	1.0	0.5	0.7	1.0	1.0	0.9	1.0	0.5	0.3	0.4	-0.8	-0.1	0.3	-0.1	-0.4	0.1	0.9	0.3	0.1	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.8	0.7	0.8	0.8	0.8	0.5	0.6	0.8	0.5	0.5	-0.4	0.7	0.9	0.7	0.5	-0.6	-0.1	0.7	0.5	0.3	0.8	0.1	0.7	0.7	0.7
Qualifications: nursing, teaching	0.4	0.7	3.5	-0.7	0.9	-1.0	-1.1	-1.7	-0.9	-0.7	-0.3	-0.3	-1.9	-0.7	-0.2	-0.4	0.3	0.6	-0.7	-0.7	-0.7	0.6	-0.4	0.6	-0.6	-0.5	-0.8
Number of self-reported non-cancer illnesses	0.4	0.6	2.9	-0.8	-1.7	-0.7	-0.8	-0.4	0.1	-0.1	-0.6	-0.7	-0.7	-0.8	-0.2	0.2	-0.2	1.2	0.1	0.4	-0.3	1.2	1.0	-1.1	0.3	0.5	-1.5
Illnesses of father: High blood pressure	0.4	0.6	4.4	-0.5	0.5	0.3	-0.3	0.0	-0.4	-0.4	-0.2	-0.2	0.2	-0.4	-0.8	-0.7	-1.2	-2.1	-0.2	-0.7	-0.6	-1.5	-1.0	-0.3	-0.3	-0.7	0.6
Ever smoked	0.4	0.7	2.8	0.1	0.7	-0.8	-1.4	-0.4	-0.6	-1.0	-0.7	-0.6	0.1	0.3	-0.2	-1.1	-0.1	-0.7	-1.7	-0.8	1.1	-0.8	-1.0	-0.5	-1.2	-1.1	-0.1
Arm fat-free mass (left)	0.4	1.9	3.7	1.2	0.8	1.8	1.9	1.4	1.5	1.6	1.9	1.7	0.5	1.2	1.6	1.6	0.3	1.4	1.0	1.3	-0.5	0.8	1.5	1.4	1.7	1.5	1.5
Age started oral contraceptive pill	0.4	0.5	2.2	0.2	0.5	-0.6	-1.2	-0.5	-0.5	-0.9	-0.6	-0.4	0.2	0.3	-0.3	-0.6	0.0	0.1	-0.8	-0.5	1.5	-0.9	-0.9	-0.1	-0.9	-0.8	-0.0
Diastolic blood pressure, automated reading	0.4	1.2	2.7	0.5	-0.6	1.0	1.2	0.6	1.3	1.2	1.2	1.1	1.3	0.6	1.1	1.6	0.2	1.3	1.2	1.6	-0.5	0.7	1.5	0.6	1.4	1.5	0.8
Ever depressed for a whole week	0.4	0.5	3.4	0.3	-0.2	-0.8	-0.0	0.3	-0.5	0.3	0.3	0.3	-0.4	0.2	0.1	-0.0	1.8	1.3	-0.5	-0.3	0.4	1.6	0.2	1.2	-0.2	-0.1	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.5	-0.8	-1.1	-1.1	-0.6	-0.3	-0.6	-0.2	-0.9	-0.9	-0.9	-0.7	-1.0	-0.3	0.3	0.1	0.0	-0.4	-0.0	0.7	0.1	-0.6	-0.6	-0.3	-1.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.3	-0.7	-0.8	-0.6	-0.1	-0.5	-0.1	-0.0	-0.1	-0.1	-1.8	-0.9	-0.4	0.5	0.1	-1.1	1.0	0.3	-1.3	1.1	0.6	0.1	0.3	0.4	-0.9
Alzheimer’s Disease (in father)	0.3	0.4	1.4	1.2	0.1	0.4	-0.2	0.8	0.4	0.3	0.1	0.3	0.4	1.2	0.8	0.4	0.3	0.7	0.2	0.5	1.0	-0.1	0.4	0.5	0.2	0.3	1.0
Ulcerative Colitis (UC)	0.3	0.6	2.8	-1.2	-1.4	-0.4	-0.0	-0.7	-0.3	-0.1	-0.2	-0.2	-1.7	-1.3	-0.9	0.2	-0.4	0.5	0.6	0.1	-1.3	0.6	0.4	0.1	0.3	0.2	-0.8
Body Mass Index (BMI) (2010)	0.3	0.5	2.5	-0.2	1.4	1.0	-0.5	-0.2	-0.2	-0.4	0.0	-0.4	-0.0	-0.1	-0.1	-0.5	-1.2	-0.3	-0.6	-0.8	0.6	-1.6	-0.4	-1.0	0.2	-0.5	0.5
Crohns Disease (2012)	0.3	0.5	1.7	-0.3	-1.1	0.2	-0.3	-0.1	0.7	-0.1	-0.5	-0.5	-0.5	-0.5	0.1	0.4	-0.8	1.3	0.7	0.8	0.6	0.5	0.9	-1.2	0.5	0.8	-0.8
Systolic Blood Pressure	0.3	1.4	4.7	-1.7	-0.3	-0.1	-0.5	-1.4	-0.9	-1.4	-1.0	-1.1	1.2	-1.7	-1.5	-1.0	-1.8	-1.4	-0.5	-1.1	-0.6	-2.2	-1.4	-1.1	-0.7	-1.2	0.0
Respiratory disease	0.3	0.6	2.2	0.6	1.3	0.3	0.1	0.4	0.3	0.3	0.8	1.0	1.5	0.4	0.3	0.7	1.4	-0.7	0.9	0.4	-0.6	0.5	0.4	1.3	0.4	0.3	1.0
Severe depression (siblings)	0.3	0.3	3.6	-0.1	-0.1	0.7	0.5	0.1	0.4	0.3	0.5	0.4	0.0	0.1	0.0	0.7	0.0	1.9	0.2	0.6	-0.5	0.3	0.6	0.3	0.8	0.7	0.4
Supplements: Glucosamine	0.3	0.3	2.3	-0.4	0.4	-0.6	-0.8	-1.0	-0.2	-0.7	-0.2	0.3	-1.5	-0.3	-0.2	0.0	0.4	-0.0	0.2	-0.0	-1.3	0.6	-0.0	0.7	-0.1	0.1	-0.1
Medication: Atenolol	0.3	0.4	3.3	0.6	-0.3	0.5	0.7	1.8	0.5	1.3	0.2	0.2	-0.3	0.7	0.4	0.3	0.1	0.8	-0.1	0.6	1.0	0.1	0.4	-0.2	0.3	0.3	0.3
Neuroticism score	0.3	0.7	4.2	-1.1	-0.4	0.8	0.6	-0.0	0.5	0.1	0.4	0.3	-0.4	-0.9	-0.4	0.7	-0.8	-0.8	1.8	0.5	-2.0	0.4	0.9	-0.2	1.2	0.9	-0.2
Trunk fat-free mass	0.3	1.9	4.1	1.4	1.4	1.8	1.9	1.4	1.3	1.6	2.0	1.8	0.7	1.4	1.8	1.3	0.7	1.2	0.6	1.0	-0.1	0.5	1.2	1.7	1.5	1.3	1.8
Father’s age at death	0.3	0.4	1.8	0.6	-1.3	-0.5	0.6	0.6	-0.4	0.8	0.0	-0.1	0.3	0.6	0.2	-0.1	1.3	0.8	-0.9	-0.1	1.1	0.5	-0.2	0.4	-0.5	-0.2	-0.1
Asthma	0.3	0.6	5.9	-0.1	2.4	0.0	-1.3	-0.2	-0.4	-0.4	0.0	0.1	0.8	-0.2	-0.4	-0.1	0.4	-1.6	-0.2	-0.3	-0.3	-0.6	-0.5	0.6	-0.2	-0.4	0.9
Trunk predicted mass	0.3	2.0	4.2	1.5	1.4	1.8	1.9	1.4	1.3	1.6	2.0	1.8	0.7	1.5	1.8	1.3	0.8	1.2	0.6	1.0	-0.1	0.5	1.2	1.7	1.5	1.2	1.9
Gout (self-reported)	0.3	0.4	2.0	0.4	0.0	0.7	0.9	0.7	0.9	0.4	0.8	0.6	0.4	0.1	0.2	0.6	-0.5	-0.3	1.4	0.6	-0.3	0.2	0.6	0.2	0.7	0.7	0.4
Comparative body size at age 10	0.3	0.7	2.8	0.4	0.3	1.7	1.0	0.7	1.0	0.2	0.7	0.7	0.7	0.4	0.9	0.7	-1.2	-0.7	1.1	0.7	-0.5	-0.9	0.6	-0.2	1.2	0.7	1.1
Wheeze or whistling in the chest in last year	0.3	0.6	1.8	0.7	0.8	0.7	0.8	1.0	0.7	0.4	0.8	0.9	1.3	0.7	0.5	0.7	0.9	0.6	0.6	0.7	0.2	0.5	0.8	0.7	0.7	0.7	0.7
Medication: Allopurinol	0.3	0.4	2.2	-0.8	-1.0	0.2	0.2	-0.2	0.5	-0.6	-0.4	-0.3	-0.5	-1.0	-0.5	0.0	-1.5	-0.5	1.4	0.3	-0.9	-0.2	0.2	-0.9	0.3	0.4	-0.4
Chest pain or discomfort	0.3	0.4	2.3	-0.5	-1.5	-0.2	0.3	-0.1	-0.1	0.5	0.1	-0.2	0.0	-0.4	-0.2	0.6	0.6	1.1	0.6	0.4	-0.5	1.2	0.7	0.1	0.3	0.4	-0.8
Age at last live birth	0.3	0.4	3.3	0.7	1.8	0.6	0.7	-0.0	0.2	-0.3	0.9	1.0	0.3	0.8	0.9	0.2	0.7	0.0	-0.2	0.0	0.4	-0.2	-0.2	1.0	0.2	-0.1	0.8
Handedness (chirality/laterality): Left-handed	0.3	0.3	3.2	-0.0	0.4	0.5	0.1	0.4	0.5	0.3	-0.1	-0.1	0.3	0.1	0.0	-0.0	-1.8	-1.0	0.0	0.3	0.1	-1.2	-0.3	-0.9	0.1	-0.0	0.3
Eye problems/disorders: Cataract	0.3	0.3	1.3	-0.6	-0.2	-1.0	0.3	-0.4	-0.6	-0.1	0.1	0.1	-0.7	-0.5	-0.1	0.0	1.1	1.2	0.0	-0.2	-0.8	0.9	0.3	0.8	-0.1	0.1	-0.0
Smoking status: Current	0.3	0.5	2.3	-0.2	-0.9	-0.3	-0.1	-0.7	0.3	-0.1	0.2	0.3	-0.7	-0.4	0.5	0.6	0.9	0.9	0.7	0.6	-1.0	1.5	1.1	0.3	0.6	0.9	-0.5
Ever taken oral contraceptive pill	0.3	0.3	0.8	0.9	-0.1	0.5	0.6	0.6	0.5	0.8	0.7	0.8	-0.0	0.8	0.6	0.5	0.7	-0.3	0.3	0.6	-0.1	0.2	0.1	0.8	0.3	0.4	0.8
Financial situation satisfaction	0.3	0.4	2.7	-0.8	-0.3	-0.4	0.1	-1.1	-0.2	-0.6	-0.1	0.1	-1.6	-0.8	0.1	-0.0	-0.1	0.8	0.5	0.0	-1.2	0.9	0.3	0.2	0.0	0.2	-0.9
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.0	-0.2	0.6	-0.6	-0.3	-0.2	-0.4	-0.3	-0.6	-0.6	0.3	-0.1	-0.3	-0.6	0.2	0.7	-1.0	-0.5	0.6	-0.4	-0.7	-0.5	-0.8	-0.7	-0.4
Medication: Lisinopril	0.3	0.4	2.2	-0.9	-0.4	-0.4	-0.9	-1.2	-0.4	-0.8	-0.3	-0.5	-0.8	-0.9	-0.5	-0.3	-0.5	-1.5	0.2	-0.4	-0.3	-0.5	-0.1	-0.3	-0.1	-0.3	-0.2
Number of operations (self-reported)	0.3	0.5	4.1	-0.7	-0.6	-0.3	-0.5	-1.0	0.1	-0.2	-0.3	-0.3	-2.0	-0.7	0.0	0.3	-0.2	-1.0	0.6	0.3	-0.7	0.7	0.6	-0.6	0.3	0.4	-0.7
Risk taking	0.3	0.5	2.5	-0.2	-0.9	-0.8	-0.6	0.0	-0.4	-0.2	-0.7	-0.7	-1.5	-0.1	0.1	-0.4	-0.1	0.5	-0.7	-0.2	1.1	0.7	0.1	-0.8	-0.4	-0.2	-1.6
Pain experienced in last month	0.3	0.5	1.9	0.4	0.8	-0.5	-0.7	0.3	-0.3	-0.5	-0.8	-0.4	0.4	0.4	-0.2	-0.7	0.4	0.9	-0.8	-0.5	1.4	-0.4	-1.2	-0.2	-1.1	-0.9	-0.4
Supplements: Calcium	0.3	0.3	2.2	-0.4	0.4	-0.2	-1.5	-0.9	-0.4	-0.8	-0.2	-0.4	0.0	-0.5	-0.6	-0.6	-0.0	0.1	-0.8	-0.7	-0.1	-0.5	-0.6	-0.1	-0.3	-0.6	-0.2
Arm predicted mass (left)	0.3	1.6	3.4	1.0	0.4	1.7	1.8	1.3	1.4	1.5	1.7	1.5	0.4	1.0	1.4	1.5	0.2	1.2	1.0	1.3	-0.5	0.8	1.5	1.1	1.6	1.5	1.2
Worry (Nagel 2018)	0.2	0.4	2.1	-0.4	-1.4	0.2	0.9	0.1	0.6	0.1	-0.2	-0.3	0.5	-0.3	-0.3	0.5	-0.5	-0.7	1.2	0.6	-0.3	0.3	0.7	-0.8	0.7	0.8	-0.4
Irritable Bowel Disease (IBD)	0.2	0.4	1.6	-0.2	-0.3	0.5	0.3	-0.1	0.8	0.2	0.0	0.2	-0.9	-0.3	0.2	0.8	-0.3	1.3	1.0	1.0	0.0	0.6	1.1	-0.2	0.9	0.9	-0.4
Reaction Time	0.2	0.4	1.6	0.4	-0.1	0.0	0.6	0.8	0.5	1.2	0.7	0.4	0.3	0.5	0.5	0.7	1.3	0.5	0.2	0.7	0.2	1.0	0.9	0.4	0.5	0.7	0.1
Mean Putamen Volume	0.2	0.2	2.6	0.7	-0.6	-0.5	-0.2	-0.3	0.1	-0.1	-0.1	-0.3	0.1	0.6	0.4	-0.1	0.5	0.4	-0.5	0.1	1.6	-0.0	0.2	-0.3	-0.2	-0.1	-0.2
Fasting Glucose	0.2	0.3	0.7	0.6	-0.6	0.5	0.5	0.4	0.4	0.6	0.6	0.4	0.4	0.6	0.6	0.5	0.5	-0.8	0.4	0.4	0.0	0.3	0.6	0.5	0.6	0.6	0.6
LDL Cholesterol	0.2	0.4	2.6	-0.1	0.1	-0.6	0.5	-0.6	0.0	0.1	0.0	0.2	-0.1	-0.3	0.5	0.6	1.6	-0.5	0.6	0.2	-0.4	1.5	0.6	0.8	0.2	0.7	0.1
Blood Platelet Count	0.2	2.5	13.2	0.3	2.2	2.2	-0.2	0.9	1.8	-0.5	-0.9	-0.5	1.5	0.7	0.9	0.2	-3.6	0.1	0.4	1.0	1.5	-3.4	0.1	-3.3	0.7	0.4	1.3
Blood Red Count	0.2	1.5	7.7	-1.5	-2.8	-1.2	-0.2	-0.6	-0.4	-0.8	-1.4	-1.2	-1.5	-1.7	-1.5	-0.3	-1.6	0.8	0.4	-0.0	-0.5	0.3	-0.1	-1.8	-0.6	-0.3	-2.4
Blood White Count	0.2	1.4	5.7	-0.5	-0.5	1.3	1.1	1.2	1.5	1.2	0.7	0.8	0.1	-0.3	0.3	1.5	-0.9	-0.4	2.4	1.5	-2.2	0.6	1.6	-0.3	1.8	1.6	0.3
Smoking Status	0.2	0.5	2.9	0.2	-0.6	-0.2	-0.1	0.4	0.5	0.8	0.5	0.5	-1.0	0.1	0.5	0.7	1.3	0.3	0.6	0.8	-0.7	1.7	1.3	0.5	0.6	0.9	-0.2
Cardiovascular Disease	0.2	0.7	3.6	-1.2	-1.6	0.1	-0.4	-0.4	0.2	-0.1	-0.8	-1.1	-0.1	-1.3	-0.9	-0.5	-1.6	-0.2	0.2	-0.1	-0.3	-0.9	0.2	-1.9	0.1	0.0	-0.4
Neuroticism	0.2	0.5	2.4	-0.3	0.5	0.9	0.8	0.5	0.6	0.4	0.7	0.6	0.1	-0.2	0.1	0.9	0.0	-0.2	1.6	0.6	-1.3	0.5	1.0	0.3	1.2	0.9	0.3
Tanning	0.2	2.6	6.1	1.5	-1.0	0.8	1.9	1.0	1.4	1.2	1.3	1.8	0.4	1.4	1.6	2.0	2.1	2.2	1.3	2.0	-0.5	2.5	2.1	1.8	1.7	2.1	0.5
Number of treatments/medications taken	0.2	0.3	1.1	-0.6	-0.8	-0.7	-0.9	-0.4	-0.1	0.1	-0.4	-0.6	-0.9	-0.7	-0.3	-0.2	0.3	0.1	-0.4	-0.1	-0.7	1.1	0.5	-0.4	0.0	0.3	-1.0
Systolic blood pressure, automated reading	0.2	0.7	2.5	-1.4	-0.8	-0.4	-0.8	-1.6	-0.7	-1.3	-0.7	-0.7	0.5	-1.3	-0.9	-0.3	-1.0	-0.7	-0.1	-0.5	-0.7	-1.0	-0.5	-0.4	-0.3	-0.5	-0.0
Medication for hormone replacement therapy	0.2	0.2	0.8	0.4	-0.4	0.7	0.0	0.2	0.5	0.4	0.7	0.5	-0.4	0.2	0.6	0.5	-0.2	-0.0	0.4	0.4	-0.3	0.5	0.8	0.5	0.9	0.7	0.2
Diabetes (father)	0.2	0.3	1.4	0.0	-0.1	0.0	-0.1	0.2	-0.2	-0.3	-0.2	-0.3	-0.1	0.0	-0.1	-0.5	-1.2	-1.1	-0.2	-0.6	0.7	-1.2	-0.7	-0.6	-0.4	-0.6	-0.1
Diabetes (mother)	0.2	0.3	2.2	-0.5	-0.4	-0.0	0.6	-0.2	0.2	0.2	0.2	0.4	-0.8	-0.5	-0.1	0.2	-0.1	0.4	0.7	0.2	-1.5	1.0	0.5	0.4	0.4	0.6	-0.6
Had menopause	0.2	0.3	2.2	-0.2	0.2	-0.7	-0.7	-0.6	-0.6	-0.2	-0.3	-0.6	0.4	-0.3	-0.2	-0.2	0.2	1.5	-0.6	-0.3	0.9	0.0	-0.2	-0.2	-0.5	-0.4	-0.5
Forced vital capacity (FVC)	0.2	0.7	3.3	-0.7	-0.5	-0.3	-0.8	-0.1	-0.1	-0.2	-1.0	-1.1	-0.8	-0.4	-0.5	-0.6	-1.4	-1.4	-0.7	-0.2	1.0	-1.1	-0.4	-1.8	-0.6	-0.5	-0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.3	-0.1	0.9	0.3	-1.2	-0.2	0.1	-0.4	-0.2	-0.4	0.4	-0.1	0.2	-0.2	-0.4	1.1	-0.5	-0.1	0.5	-0.5	-0.2	-0.8	-0.0	-0.2	-0.1
Illnesses of siblings	0.2	0.3	1.8	0.6	0.8	-0.4	0.3	0.3	-0.0	0.4	0.1	0.3	0.3	0.7	0.7	-0.0	0.9	1.3	-0.8	0.1	0.7	0.6	-0.3	0.6	-0.5	-0.1	-0.2
Impedance of arm (right)	0.2	0.9	4.3	1.4	1.5	0.4	-0.1	0.6	0.2	-0.1	0.3	0.4	2.1	1.5	0.5	-0.4	0.4	-1.0	-0.8	-0.2	1.8	-1.4	-0.9	0.2	-0.5	-0.6	1.2
Worrier / anxious feelings	0.2	0.4	1.8	-1.0	-0.2	-0.1	-0.1	-0.8	-0.5	-1.0	-0.3	-0.4	0.4	-0.8	-0.7	-0.4	-1.4	-0.3	0.1	-0.6	-0.2	-0.5	-0.3	-0.5	-0.0	-0.4	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.3	-0.5	-0.3	0.1	0.2	0.9	-0.4	0.6	0.2	0.1	-0.8	-0.4	-0.4	0.2	0.7	-1.1	0.8	-0.3	-0.7	0.8	0.3	0.3	0.4	0.0	-0.6
Noisy workplace	0.2	0.3	2.1	0.0	0.4	0.1	0.7	-0.2	-0.2	-1.0	0.3	0.6	1.5	0.2	-0.2	-0.2	-0.2	-0.1	0.3	-0.3	-0.7	-0.6	-0.6	0.5	-0.2	-0.5	0.4
Standing height	0.2	2.1	6.5	2.1	2.4	1.3	1.5	1.3	0.6	0.7	1.6	1.4	2.6	2.2	1.5	0.3	1.0	-0.5	-0.5	0.1	1.7	-0.9	-0.3	1.7	0.3	0.0	2.5
Birth weight of first child	0.2	0.4	1.9	0.0	0.7	0.3	-0.0	-0.4	-0.2	-0.8	-0.4	-0.5	0.4	0.3	0.1	-0.5	-1.2	0.6	-1.3	-0.5	0.5	-1.4	-0.9	-1.0	-0.5	-0.8	0.1
Peak expiratory flow (PEF)	0.2	0.5	2.5	-0.5	0.3	-0.2	-0.9	-0.2	-0.4	-0.5	-0.6	-0.7	-0.0	-0.3	-0.5	-0.6	-1.0	-1.6	-0.8	-0.4	1.0	-1.4	-0.6	-1.1	-0.7	-0.7	-0.0
Exposure to tobacco smoke outside home	0.2	0.3	1.3	0.3	-1.2	0.6	0.7	-0.0	0.6	-0.1	-0.0	-0.1	-0.1	0.2	0.9	0.6	-0.2	-0.4	0.5	0.6	0.5	0.1	0.7	-0.6	0.6	0.6	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.1	0.3	0.0	-0.6	-0.3	-0.3	-0.7	0.3	0.2	-0.0	-0.3	0.3	-0.3	-0.4	1.0	0.2	-1.0	-0.6	0.5	0.4	-0.6	0.8	-0.6	-0.6	-0.2
Eye problems/disorders: None of the above	0.2	0.2	0.6	-0.4	-0.7	-0.2	-0.1	-0.5	-0.3	-0.2	-0.4	-0.4	0.1	-0.4	-0.5	-0.4	-0.6	-0.4	-0.1	-0.4	-0.0	-0.1	-0.6	-0.4	-0.5	-0.5	-0.8
Mean time to correctly identify matches	0.2	0.4	2.0	0.1	-1.0	-0.4	0.0	0.5	0.4	1.0	0.3	-0.0	0.1	0.2	0.2	0.4	1.0	1.4	-0.0	0.6	0.4	1.1	0.9	-0.1	0.3	0.6	-0.4
Alcohol intake frequency.	0.2	0.5	1.7	-0.9	-1.3	-1.0	0.5	-0.5	-0.8	0.1	0.1	-0.0	-0.7	-0.9	-0.5	-0.0	1.0	0.4	0.2	-0.3	-1.1	1.1	0.0	0.9	-0.2	-0.1	-0.6
Family relationship satisfaction	0.2	0.3	1.6	-0.7	-0.9	-0.5	0.2	-0.6	-0.2	-0.3	-0.1	-0.2	-1.2	-0.8	-0.2	-0.1	-0.0	0.4	-0.1	-0.2	-0.6	0.7	-0.0	-0.1	-0.1	0.0	-1.1
Hypertension (Self-reported)	0.2	0.5	2.7	-0.9	-1.6	0.0	-0.4	-0.4	0.0	-0.3	-0.7	-1.1	-0.1	-0.9	-0.6	-0.4	-1.1	0.7	-0.4	-0.1	0.6	-0.8	0.3	-1.6	0.0	-0.0	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	2.0	-0.0	-1.3	-0.6	-0.5	-0.0	-0.3	0.3	0.1	0.1	0.1	-0.1	-0.3	0.1	0.6	1.4	-0.0	-0.0	-0.8	1.2	0.3	0.6	-0.0	0.2	-0.6
Mineral and other dietary supplements	0.2	0.2	1.2	-0.7	-0.4	-0.7	-0.1	0.1	-0.6	-0.2	-0.6	-0.5	-0.6	-0.6	-0.5	-0.4	0.1	0.6	-0.1	-0.4	0.2	0.4	-0.3	-0.2	-0.6	-0.4	-1.1
Asthma (self-reported)	0.2	0.4	4.2	-0.3	2.0	-0.1	-1.2	-0.2	-0.4	-0.4	-0.1	-0.0	0.7	-0.4	-0.5	-0.1	0.1	-1.4	-0.3	-0.4	-0.3	-0.6	-0.5	0.4	-0.2	-0.4	0.6
Average weekly champagne plus white wine intake	0.2	0.3	0.8	0.5	0.2	0.3	-0.4	0.2	0.8	0.6	0.5	0.6	-0.6	0.4	0.8	0.7	0.5	0.2	0.2	0.9	-0.5	0.7	0.8	0.1	0.8	0.9	0.2
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.0	-0.6	0.2	-0.1	0.1	-0.7	-0.8	-0.6	-0.2	-0.3	1.0	-0.6	-0.5	-0.4	-0.2	-0.2	-0.2	-0.7	-0.4	-0.6	-0.6	0.3	-0.3	-0.6	0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.8	0.3	-0.7	0.6	0.8	-0.1	0.5	0.8	0.7	0.4	0.1	0.1	0.2	0.6	-0.2	-0.5	0.6	0.6	-0.9	0.3	0.7	0.2	0.8	0.7	0.6
Medication: Atorvastatin	0.2	0.2	1.5	-0.5	-1.2	0.0	0.3	-0.1	0.0	0.1	-0.2	-0.4	-0.5	-0.7	-0.3	0.2	-0.4	-1.0	0.7	0.1	-0.1	0.3	0.6	-0.4	0.2	0.3	-0.5
Basal cell carcinoma (self-reported)	0.2	0.2	1.5	-0.1	-0.5	0.2	0.4	-0.2	0.5	0.8	0.4	0.2	0.4	-0.1	0.3	0.5	-0.1	1.2	0.2	0.7	-0.6	0.5	0.5	0.1	0.5	0.7	-0.0
Impedance of whole body	0.2	0.8	3.9	-0.1	-0.3	-1.0	-0.8	-0.6	-1.0	-0.9	-0.8	-0.7	0.7	-0.0	-0.7	-1.0	0.3	-2.0	-0.8	-1.0	1.3	-0.7	-1.2	-0.3	-1.2	-1.1	-0.5
Coronary Artery Disease (CAD)	0.1	0.1	1.5	-0.2	-0.0	-0.1	-0.2	-0.3	-0.0	-0.4	-0.2	-0.1	0.2	-0.1	-0.4	0.2	-0.7	1.2	-0.0	0.4	0.3	0.0	-0.3	-0.4	-0.3	-0.0	-0.4
Neuroticism (2016)	0.1	0.2	0.7	0.2	-0.7	0.4	0.8	0.7	0.1	0.2	-0.2	-0.4	0.6	0.3	0.1	-0.4	-0.1	-0.4	-0.4	-0.2	0.6	-0.2	-0.5	-0.1	-0.2	-0.1	-0.0
Height	0.1	1.2	6.9	1.6	1.2	0.3	1.4	0.7	0.2	0.1	0.8	0.5	2.6	1.7	0.8	-0.0	0.7	-1.0	-0.5	-0.2	2.3	-0.7	-0.4	0.7	-0.4	-0.3	1.1
Chronotype (morning person)	0.1	0.2	1.5	-0.1	-0.0	-0.0	1.2	-0.6	-0.2	-0.3	0.1	-0.1	0.7	-0.1	-0.2	-0.2	-0.6	1.0	0.2	-0.2	0.1	-0.6	-0.3	-0.1	-0.3	-0.2	0.3
Hair Pigment	0.1	4.0	8.2	-2.7	-1.6	-1.8	-1.9	-2.8	-2.3	-2.5	-1.9	-2.1	-1.8	-2.9	-2.4	-2.1	-1.6	-0.3	-1.1	-2.3	-0.9	-0.8	-1.9	-1.4	-1.7	-1.9	-2.5
Relative age of first facial hair	0.1	0.3	1.0	0.0	0.3	-0.7	-0.4	-0.6	-0.7	-0.2	0.1	0.1	-0.8	0.2	-0.2	-0.5	0.8	0.6	-1.0	-0.5	0.2	0.3	-0.7	0.7	-0.8	-0.6	-0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.1	0.3	0.1	0.5	0.1	-0.1	0.1	0.3	0.2	0.5	0.2	0.1	-0.1	0.0	0.5	-0.3	-0.2	0.1	-0.4	-0.3	0.3	-0.2	-0.3	0.4
High blood pressure	0.1	0.3	1.9	-0.9	-1.4	0.2	-0.2	-0.4	0.0	-0.2	-0.4	-0.7	-0.2	-1.0	-0.6	-0.2	-1.0	0.4	-0.0	-0.0	0.0	-0.7	0.3	-1.1	0.2	0.1	0.0
Sitting height	0.1	0.6	2.7	0.5	0.3	-0.2	0.0	-0.7	-0.8	-1.0	0.4	0.3	1.0	0.6	0.1	-0.8	0.3	0.9	-1.6	-0.9	0.6	-0.4	-1.1	1.4	-0.8	-0.8	0.5
Past tobacco smoking	0.1	0.2	1.2	-0.4	-1.1	-0.1	0.6	-0.3	-0.1	-0.0	-0.5	-0.6	-0.1	-0.4	-0.2	0.0	-0.4	1.1	0.3	0.0	0.2	0.1	0.0	-0.6	0.0	0.1	-0.6
Nervous feelings	0.1	0.2	1.0	0.0	-0.4	0.1	0.8	0.1	0.4	0.3	0.1	-0.2	0.8	0.3	0.2	0.3	-0.1	-1.0	0.2	0.4	0.3	-0.2	0.4	-0.5	0.3	0.4	0.2
Falls in the last year	0.1	0.1	1.2	-0.1	-0.4	0.3	0.5	0.0	-0.5	-0.1	0.5	0.4	-0.0	-0.1	-0.3	-0.0	-0.3	0.1	0.4	-0.3	-0.3	-0.3	-0.2	1.1	0.1	-0.1	0.7
Impedance of arm (left)	0.1	0.4	1.7	0.8	0.8	0.1	-0.0	0.3	-0.0	-0.1	0.2	0.3	1.3	0.9	0.1	-0.3	0.4	-1.3	-0.3	-0.2	1.0	-0.8	-0.7	0.3	-0.5	-0.4	0.7
Birth weight	0.1	0.3	1.6	0.4	1.3	0.1	-0.2	-0.1	-0.5	0.1	-0.0	-0.3	0.3	0.2	0.0	-0.6	-0.2	-0.4	-1.1	-0.7	0.4	-1.1	-0.8	0.1	-0.5	-0.7	0.6
Forced vital capacity (FVC), Best measure	0.1	0.5	2.2	-1.0	-0.1	-0.4	-0.9	-0.3	-0.4	-0.0	-0.7	-0.9	-1.4	-0.8	-0.3	-0.5	-0.9	-1.5	-0.7	-0.3	0.1	-0.5	-0.3	-1.2	-0.5	-0.4	-0.6
Comparative height size at age 10	0.1	0.8	5.2	0.8	1.4	1.2	0.9	0.3	0.7	-0.1	0.6	0.5	2.3	0.8	0.6	0.4	-0.5	0.1	0.3	0.4	1.2	-1.0	0.3	0.2	0.5	0.4	1.4
Back pain experienced in last month	0.1	0.1	0.6	-0.1	0.7	0.5	0.2	-0.0	0.1	-0.2	0.0	-0.1	0.1	-0.0	-0.0	0.1	-0.7	-0.4	-0.1	-0.0	-0.2	-0.6	0.1	-0.4	0.3	0.1	0.4
Alcohol drinker status: Never	0.1	0.1	0.6	-0.1	0.1	-0.2	-0.4	-0.0	-0.3	0.1	0.5	0.1	-0.8	-0.1	0.1	-0.3	-0.0	-0.2	-0.3	-0.4	-0.7	0.1	-0.3	0.4	-0.1	-0.4	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.4	2.2	0.9	1.5	-0.4	-0.2	0.2	-0.4	-0.1	0.0	0.3	0.4	1.0	0.6	-0.3	0.8	-0.4	-0.9	-0.4	0.8	0.3	-0.8	0.8	-0.7	-0.5	-0.1
Blood Eosinophil Count	0.0	0.3	2.2	0.5	0.2	0.7	0.9	1.5	0.6	0.6	0.6	0.7	0.9	0.5	0.5	0.2	0.4	-0.1	0.1	0.1	-0.7	0.4	-0.0	0.5	0.5	0.3	0.1
Long-standing illness, disability or infirmity	0.0	0.1	0.2	-0.3	-0.5	-0.1	0.1	-0.4	0.1	-0.2	-0.2	-0.2	-0.1	-0.4	-0.1	0.2	-0.5	0.3	0.3	0.2	-0.2	0.2	0.3	-0.3	0.1	0.2	-0.4

Hub : Genes

LACTB2

Models

Trait associations