TWAS
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Genes
Traits
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Traits
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Lung FEV1/FVC ratio
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chr1:154,956,662-155,445,842
Best TWAS P=3.59e-16 · Best GWAS P=5.04e-20 conditioned to 1.37e-05
155M
155.1M
155.2M
155.3M
155.4M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Prostate Adenocarcinoma
GBA
0.05
0.01
lasso
2
0.01
0.023
-9.2
8.2
3.6e-16
-0.93
0
0.87
TRUE