Best TWAS P=3.7e-11 · Best GWAS P=4.18e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MTMR11 | 0.08 | 0.04 | lasso | 4 | 0.05 | 3.5e-05 | 6.6 | 6.5 | 6.8e-11 | 0.94 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | HIST2H2AA3 | 0.22 | 0.02 | enet | 20 | 0.12 | 1.8e-09 | -4.6 | -5.7 | 1.1e-08 | -0.55 | 0.04 | 0.94 | FALSE |
| 3 | GTEx | Lung | MTMR11 | 0.08 | 0.04 | lasso | 8 | 0.03 | 3.0e-03 | 6.6 | 6.6 | 4.4e-11 | 0.97 | 0.00 | 0.98 | FALSE |
| 4 | GTEx | Thyroid | MTMR11 | 0.09 | 0.05 | enet | 9 | 0.06 | 1.5e-05 | 5.4 | 5.5 | 3.1e-08 | 0.54 | 0.06 | 0.86 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | C1orf54 | 0.04 | 0.02 | blup | 17 | 0.02 | 1.4e-03 | -4.9 | 5.4 | 7.2e-08 | 0.11 | 0.00 | 0.92 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MTMR11 | 0.02 | 0.02 | lasso | 3 | 0.02 | 3.7e-03 | 6.6 | 6.6 | 3.7e-11 | 1.00 | 0.00 | 0.91 | TRUE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SF3B4 | 0.03 | 0.02 | blup | 10 | 0.01 | 1.4e-02 | 6.6 | 6.2 | 4.0e-10 | 0.95 | 0.00 | 0.94 | FALSE |