Best TWAS P=8.25e-09 · Best GWAS P=2.41e-06 conditioned to 3.34e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | FCGR2C | 0.17 | 0.03 | enet | 30 | 0.06 | 2.5e-05 | -4.4 | 5.2 | 1.9e-07 | -0.22 | 0.02 | 0.89 | FALSE |
2 | GTEx | Whole Blood | FCGR2B | 0.26 | 0.10 | enet | 35 | 0.14 | 9.4e-13 | -4.4 | -5.1 | 3.0e-07 | 0.13 | 0.02 | 0.92 | FALSE |
3 | NTR | Blood | FCGR2B | 0.25 | 0.06 | enet | 88 | 0.18 | 7.9e-57 | -2.7 | -5.3 | 1.1e-07 | 0.17 | 0.13 | 0.51 | FALSE |
4 | YFS | Blood | FCGR2B | 0.54 | 0.21 | enet | 101 | 0.38 | 9.1e-133 | -4.4 | -5.8 | 8.2e-09 | 0.10 | 0.02 | 0.92 | TRUE |