[Hub]/) : Traits : Lung FEV1/FVC ratio : ← →

chr11:34,189,564-35,732,073

Best TWAS P=1.88e-15 · Best GWAS P=5.8e-13 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	APIP	0.46	0.30	enet	67	0.47	6.6e-43	-3.7	-6.4	1.2e-10	0.11	1.00	0.00	TRUE
2	GTEx	Adipose Visceral Omentum	APIP	0.43	0.15	enet	50	0.31	1.1e-16	-3.7	-5.8	6.3e-09	0.09	1.00	0.00	TRUE
3	GTEx	Artery Aorta	APIP	0.47	0.32	enet	31	0.45	1.6e-27	-3.9	-5.8	7.9e-09	0.08	1.00	0.00	TRUE
4	GTEx	Artery Coronary	APIP	0.51	0.34	enet	19	0.46	1.8e-17	-3.7	-5.9	2.9e-09	0.14	1.00	0.00	FALSE
5	GTEx	Artery Tibial	PDHX	0.13	0.08	lasso	11	0.09	1.9e-07	5.6	5.4	6.1e-08	0.01	0.99	0.01	FALSE
6	GTEx	Artery Tibial	APIP	0.46	0.29	enet	57	0.40	4.6e-33	-3.7	-5.5	5.0e-08	0.05	1.00	0.00	TRUE
7	GTEx	Brain Hypothalamus	APIP	0.55	0.47	enet	42	0.55	2.1e-15	-3.7	-5.4	6.2e-08	0.17	0.98	0.01	TRUE
8	GTEx	Brain Putamen basal ganglia	APIP	0.41	0.43	enet	19	0.43	1.4e-11	-3.9	-5.1	2.7e-07	0.06	0.94	0.05	FALSE
9	GTEx	Breast Mammary Tissue	APIP	0.49	0.32	lasso	8	0.47	3.7e-27	-3.9	-5.3	8.8e-08	0.03	1.00	0.00	FALSE
10	GTEx	Breast Mammary Tissue (Male)	APIP	0.49	0.12	lasso	8	0.21	1.4e-05	-3.7	-6.2	6.6e-10	0.09	0.37	0.34	FALSE
11	GTEx	Breast Mammary Tissue (Female)	APIP	0.36	0.20	enet	42	0.30	1.4e-09	5.6	-5.6	2.2e-08	0.02	0.91	0.03	TRUE
12	GTEx	Colon Transverse	APIP	0.21	0.09	lasso	16	0.08	1.7e-04	6.8	-7.6	3.2e-14	0.06	0.10	0.88	TRUE
13	GTEx	Esophagus Mucosa	APIP	0.50	0.36	lasso	18	0.45	4.9e-33	5.6	-5.2	1.6e-07	0.02	0.99	0.01	TRUE
14	GTEx	Esophagus Muscularis	PDHX	0.33	0.17	lasso	18	0.23	4.1e-14	5.6	6.7	1.7e-11	-0.03	0.20	0.80	FALSE
15	GTEx	Esophagus Muscularis	APIP	0.58	0.50	enet	54	0.56	1.9e-40	-3.7	-5.3	1.4e-07	0.12	1.00	0.00	FALSE
16	GTEx	Heart Atrial Appendage	APIP	0.49	0.30	lasso	12	0.35	2.2e-16	-3.7	-5.3	1.0e-07	0.07	1.00	0.00	FALSE
17	GTEx	Heart Left Ventricle	APIP	0.38	0.15	enet	32	0.31	9.5e-17	5.6	-5.6	2.2e-08	0.10	0.99	0.01	FALSE
18	GTEx	Liver	APIP	0.27	0.19	lasso	4	0.15	4.5e-05	5.6	-5.9	4.9e-09	0.01	0.45	0.09	TRUE
19	GTEx	Muscle Skeletal	APIP	0.27	0.16	lasso	10	0.20	6.0e-19	5.7	-5.9	4.8e-09	0.01	0.99	0.01	FALSE
20	GTEx	Pancreas	PDHX	0.28	0.06	lasso	17	0.07	8.4e-04	5.7	7.9	1.9e-15	-0.07	0.53	0.20	TRUE
21	GTEx	Pancreas	APIP	0.47	0.28	enet	37	0.45	3.9e-21	-3.9	-5.5	4.1e-08	0.05	1.00	0.00	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	APIP	0.52	0.26	lasso	17	0.51	1.2e-31	-3.7	-5.7	1.4e-08	0.03	1.00	0.00	FALSE
23	GTEx	Spleen	APIP	0.75	0.26	enet	48	0.55	7.6e-17	-3.9	-5.6	2.4e-08	0.02	0.94	0.02	FALSE
24	GTEx	Uterus	APIP	0.56	0.24	enet	47	0.26	3.7e-06	-3.9	-5.7	1.2e-08	0.00	0.33	0.10	FALSE
25	GTEx	Whole Blood	APIP	0.18	0.11	lasso	17	0.10	1.2e-09	5.6	-5.2	1.7e-07	-0.02	0.99	0.01	FALSE
26	METSIM	Adipose	APIP	0.25	0.20	lasso	12	0.31	1.6e-46	5.7	-5.6	2.3e-08	0.03	0.99	0.01	FALSE
27	YFS	Blood	APIP	0.29	0.30	lasso	9	0.38	2.8e-131	5.7	-6.0	1.8e-09	0.02	0.99	0.01	FALSE
28	YFS	Blood	PDHX	0.06	0.04	lasso	8	0.06	9.1e-18	6.5	-5.1	3.0e-07	0.07	0.33	0.67	FALSE
29	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PDHX	0.03	0.01	blup	112	0.02	8.3e-03	-2.9	6.3	4.0e-10	-0.05	0.04	0.75	FALSE
30	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	APIP	0.12	0.11	lasso	2	0.10	1.3e-05	5.6	-5.6	2.1e-08	0.00	0.76	0.05	FALSE
31	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PDHX	0.18	0.20	lasso	14	0.25	2.6e-14	6.8	6.4	1.8e-10	-0.07	0.02	0.98	FALSE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	APIP	0.24	0.05	blup	106	0.14	2.9e-06	-3.9	-5.4	7.7e-08	0.02	0.40	0.21	TRUE